KEGG   Lipotes vexillifer (Yangtze River dolphin): 103086280
Entry
103086280         CDS       T03090                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00562  Inositol phosphate metabolism
lve01100  Metabolic pathways
lve04015  Rap1 signaling pathway
lve04020  Calcium signaling pathway
lve04022  cGMP-PKG signaling pathway
lve04062  Chemokine signaling pathway
lve04070  Phosphatidylinositol signaling system
lve04071  Sphingolipid signaling pathway
lve04072  Phospholipase D signaling pathway
lve04081  Hormone signaling
lve04082  Neuroactive ligand signaling
lve04261  Adrenergic signaling in cardiomyocytes
lve04270  Vascular smooth muscle contraction
lve04310  Wnt signaling pathway
lve04371  Apelin signaling pathway
lve04540  Gap junction
lve04611  Platelet activation
lve04613  Neutrophil extracellular trap formation
lve04621  NOD-like receptor signaling pathway
lve04713  Circadian entrainment
lve04720  Long-term potentiation
lve04723  Retrograde endocannabinoid signaling
lve04724  Glutamatergic synapse
lve04725  Cholinergic synapse
lve04726  Serotonergic synapse
lve04728  Dopaminergic synapse
lve04730  Long-term depression
lve04742  Taste transduction
lve04750  Inflammatory mediator regulation of TRP channels
lve04911  Insulin secretion
lve04912  GnRH signaling pathway
lve04915  Estrogen signaling pathway
lve04916  Melanogenesis
lve04918  Thyroid hormone synthesis
lve04919  Thyroid hormone signaling pathway
lve04921  Oxytocin signaling pathway
lve04922  Glucagon signaling pathway
lve04924  Renin secretion
lve04925  Aldosterone synthesis and secretion
lve04926  Relaxin signaling pathway
lve04927  Cortisol synthesis and secretion
lve04928  Parathyroid hormone synthesis, secretion and action
lve04929  GnRH secretion
lve04933  AGE-RAGE signaling pathway in diabetic complications
lve04934  Cushing syndrome
lve04935  Growth hormone synthesis, secretion and action
lve04961  Endocrine and other factor-regulated calcium reabsorption
lve04970  Salivary secretion
lve04971  Gastric acid secretion
lve04972  Pancreatic secretion
lve04973  Carbohydrate digestion and absorption
lve05010  Alzheimer disease
lve05016  Huntington disease
lve05017  Spinocerebellar ataxia
lve05022  Pathways of neurodegeneration - multiple diseases
lve05142  Chagas disease
lve05143  African trypanosomiasis
lve05146  Amoebiasis
lve05163  Human cytomegalovirus infection
lve05200  Pathways in cancer
lve05415  Diabetic cardiomyopathy
lve05417  Lipid and atherosclerosis
Module
lve_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:lve00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103086280 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    103086280 (PLCB2)
   04310 Wnt signaling pathway
    103086280 (PLCB2)
   04371 Apelin signaling pathway
    103086280 (PLCB2)
   04020 Calcium signaling pathway
    103086280 (PLCB2)
   04070 Phosphatidylinositol signaling system
    103086280 (PLCB2)
   04072 Phospholipase D signaling pathway
    103086280 (PLCB2)
   04071 Sphingolipid signaling pathway
    103086280 (PLCB2)
   04022 cGMP-PKG signaling pathway
    103086280 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    103086280 (PLCB2)
   04081 Hormone signaling
    103086280 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103086280 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103086280 (PLCB2)
   04613 Neutrophil extracellular trap formation
    103086280 (PLCB2)
   04621 NOD-like receptor signaling pathway
    103086280 (PLCB2)
   04062 Chemokine signaling pathway
    103086280 (PLCB2)
  09152 Endocrine system
   04911 Insulin secretion
    103086280 (PLCB2)
   04922 Glucagon signaling pathway
    103086280 (PLCB2)
   04929 GnRH secretion
    103086280 (PLCB2)
   04912 GnRH signaling pathway
    103086280 (PLCB2)
   04915 Estrogen signaling pathway
    103086280 (PLCB2)
   04921 Oxytocin signaling pathway
    103086280 (PLCB2)
   04926 Relaxin signaling pathway
    103086280 (PLCB2)
   04935 Growth hormone synthesis, secretion and action
    103086280 (PLCB2)
   04918 Thyroid hormone synthesis
    103086280 (PLCB2)
   04919 Thyroid hormone signaling pathway
    103086280 (PLCB2)
   04928 Parathyroid hormone synthesis, secretion and action
    103086280 (PLCB2)
   04916 Melanogenesis
    103086280 (PLCB2)
   04924 Renin secretion
    103086280 (PLCB2)
   04925 Aldosterone synthesis and secretion
    103086280 (PLCB2)
   04927 Cortisol synthesis and secretion
    103086280 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103086280 (PLCB2)
   04270 Vascular smooth muscle contraction
    103086280 (PLCB2)
  09154 Digestive system
   04970 Salivary secretion
    103086280 (PLCB2)
   04971 Gastric acid secretion
    103086280 (PLCB2)
   04972 Pancreatic secretion
    103086280 (PLCB2)
   04973 Carbohydrate digestion and absorption
    103086280 (PLCB2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    103086280 (PLCB2)
  09156 Nervous system
   04724 Glutamatergic synapse
    103086280 (PLCB2)
   04725 Cholinergic synapse
    103086280 (PLCB2)
   04728 Dopaminergic synapse
    103086280 (PLCB2)
   04726 Serotonergic synapse
    103086280 (PLCB2)
   04720 Long-term potentiation
    103086280 (PLCB2)
   04730 Long-term depression
    103086280 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    103086280 (PLCB2)
  09157 Sensory system
   04742 Taste transduction
    103086280 (PLCB2)
   04750 Inflammatory mediator regulation of TRP channels
    103086280 (PLCB2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103086280 (PLCB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103086280 (PLCB2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    103086280 (PLCB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103086280 (PLCB2)
   05142 Chagas disease
    103086280 (PLCB2)
   05143 African trypanosomiasis
    103086280 (PLCB2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103086280 (PLCB2)
   05016 Huntington disease
    103086280 (PLCB2)
   05017 Spinocerebellar ataxia
    103086280 (PLCB2)
   05022 Pathways of neurodegeneration - multiple diseases
    103086280 (PLCB2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103086280 (PLCB2)
   05415 Diabetic cardiomyopathy
    103086280 (PLCB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103086280 (PLCB2)
   04934 Cushing syndrome
    103086280 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lve04131]
    103086280 (PLCB2)
Enzymes [BR:lve01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     103086280 (PLCB2)
Membrane trafficking [BR:lve04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    103086280 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    103086280 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh C2 EF-hand_like Caskin-Pro-rich
Other DBs
NCBI-GeneID: 103086280
NCBI-ProteinID: XP_007460267
UniProt: A0A340XJH6
Position
Unknown
AA seq 1420 aa
MSLLNPVLQPPGVKAYLSQGERFIRWDDETIASPVILRVDPKGYYLYWTYQNKEMEFLDI
TSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNNFLLKTLTVVSGPDMVDLTFHNFVSYKEN
VGKDWAEDVLALAKHPLMANASRSTFLDKSLVKLKMQLNPEGKIPVKNFFQMFPADRKRV
EAALSACHLPKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHL
AKFINQKQRDSRLNSLLFPLARPDQVQGLIDKYEPRGINVQRGQLSPEGMVWFLCGPENS
VLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDCW
KGKPPDEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKMA
EYCRTIFGDMLLTEPLEKFPLKPGIPLPSPEDLRGKILIKNKKKQFSGPPAPSQEPGGEA
EGSGPPNVPVGEDTVWAGEEGAELEEEEVEEEEEESGSLDEEGMKEMQSDEGTAGLEVTA
YKEMSSLVNYVQPTKFISFESSAQKNRSYVISSFTELKAYDLLSKSSVQFVDYNKRQMSR
IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMR
RLDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDSKRRYRTKL
SPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEDGNKFLGHRIIPINALNSGYHHLCL
HSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFSAHDKKSVKLKEAMGGLPE
NPFPLGSPVACQVNAASAPTSNGSAAAGAKAREEATKEAAEPRTASVEELRELKGVVKLQ
RRHEKELRELERRGARRWEELLQRGAAQRAELRPPGAGGGGDVRGRKLGPGKGSRKKRTP
PGEDPAGAVPAEGPEGAGARLRELRDRLELELLQQGEEQCECVLRCRAQQVAEQMTKMME
LAREKQAAELKILKETLETDTKEVKKKLEAKRLDRIQAMMKVTTDKMAQERLKREINNSH
IQEVVQVIKQMTENLENHQEKLEEKQAACLEQIREMEKQFQQEALAQYEAKMKGLEVEVK
ESVRTYLRACLPSVEEDKPERPCRVSRELCEQDALTEKTDAQESLLRCPHALGMFCKDIH
PSLGPLWISQPRATRPNPAELVQRDRRGGGAEELLTGLQYSRILRRPLQSPRLRTASFSA
AGSWQAGALSRMETSEIRARTPPPPPPRRISVCGRNNCVCVRDSLHFQWRFPARLRAPNP
AQRSCTDGGSPRLFRRAQGPASFYGAPGTDSGGGGGWGEKTVTLGLARSGACGPLRAAPA
PSPLPQPQGSAEEKLLPDVVAHREVGEGQGRSPPPRQFRP
NT seq 4263 nt   +upstreamnt  +downstreamnt
atgtctctgcttaaccctgtcctgcaaccccccggggtgaaggcctatctgagccaaggg
gagcgcttcatcagatgggatgatgaaacaatagcctccccggttatcctccgtgtggat
cccaagggctactacttgtactggacatatcagaataaggagatggagtttctggatatc
accagcatccgggacacacgctttgggaagtttgccaagatgcccaagagccagaagctc
cgggatgtctttaacatggactttcctgacaacaacttcctgctgaagacgctcaccgtg
gtgtctggccccgacatggtggacctcaccttccataacttcgtctcctacaaagagaac
gtgggcaaggactgggctgaagatgtcctggctctggccaagcacccgctgatggccaat
gcctcccgcagcaccttcctggacaagagcctggtgaaactcaagatgcagctcaacccc
gaaggaaagattcctgtgaagaattttttccagatgtttcctgctgaccgcaagcgggtg
gaagctgccctcagcgcctgccacctcccaaaaggcaagaatgatgccatcaatcccgag
gacttcccagaatccgtctacaagagtttcctcatgagcctttgtcctcggccagaaata
gatgagatcttcacttcctaccatgccaaggccaaaccctacatgactaaggagcacctg
gccaaattcatcaaccagaaacagcgcgactccaggctcaactccctgctgttcccgctt
gcgcggcctgaccaggtgcagggcctcatcgacaagtacgagcccagaggcatcaacgtg
cagaggggccagctgtcccccgagggcatggtatggttcctctgcggaccagagaacagc
gtgctggcccaggacaagctgctgctgcaccacgacatgacgcagccgctcaaccattac
ttcatcaactcctcccacaacacctacctgacagccggccagttctcaggcctttcctct
gccgagatgtaccgccaggtgctgctggcgggctgccgctgcgtggagctggactgctgg
aaggggaagccccctgacgaggagcccatcatcacccacggcttcaccatgaccacagac
atctatttcaaggaagcaattgaagctattgcagaaagtgcctttaagacctccccttat
ccggtcatcctgtcgtttgaaaaccacgtggactcaccccgccaacaggctaagatggcc
gagtactgccgaacgatatttggggatatgctgctcacagagccactggaaaagtttcca
ctgaaaccaggcatccccctgcccagccctgaggatctccgaggcaagatcctcatcaag
aacaagaagaagcagttttctggtcccccagcccccagccaggagccgggtggggaggct
gaggggagcggcccacccaatgtccctgtgggtgaggacacagtgtgggctggtgaggaa
ggggccgagctggaggaggaggaggtggaagaggaagaggaggagtcgggaagcctggat
gaagaagggatgaaggagatgcagtcagatgagggcacagcgggcctggaggtgacggct
tacaaggagatgtccagcctagtcaactacgtccaacccaccaagttcatctccttcgag
tcctctgcccagaagaaccgaagttatgtcatttcctccttcacggagctcaaggcttac
gacctgctctccaagtcctcagtgcagtttgtggactacaacaagcgccagatgagccgc
atctaccccaagggcacccgcatggactcctccaactacatgccccagatgttctggaat
gctggttgccagatggttgccctcaacttccagacgatggacctgcccatgcagcagaac
atggcgctctttgagttcaatgggcagagtggctacctcctcaagcacgagttcatgcgt
cggttagacaagcagttcaaccccttctcggtggaccgcatcgacgtggtggtagccacc
accctttccattacggtgatctctgggcagttcctgtcagaacgcagcgtgcgcacctat
gtggaagtggagctgtttggccttcctggggactccaagaggcgctatcgcaccaagctg
tcacccagtaccaattccatcaatcctgtctggaaggaggagccctttgtctttgaaaag
atcttgatgcctgagctggcctccctcagggtggctgtgatggaggacggcaacaagttt
cttggacaccgcataatccccatcaatgccctgaattctggataccaccatctgtgcctg
cacagcgagagcaacatgccgctcaccatgcctgcactctttgtcttcctggagatgaag
gactatgtacctgacacctgggcagatctcacggtggccctcgccaatcccatcaagttc
ttcagtgcccatgataagaagtctgtgaagctcaaggaagccatgggaggcctgcctgag
aatcccttccctctcgggagtccagttgcctgccaggtcaatgcggcatcagctccaacg
agcaacgggtcagcagcagccggggccaaggccagggaggaggccacgaaagaagctgcg
gagccgcggaccgccagcgtggaggagctgcgggagctgaagggcgtcgtgaagctgcag
cggcggcacgagaaggagctgcgggagctggagcggcgcggcgcgcggcgctgggaggag
ctgctgcagaggggcgcagcgcagcgggccgagctccggccgccgggcgctgggggcggc
ggcgacgtccggggccgcaagctcggcccggggaaaggctcccgcaaaaagaggaccccg
ccgggcgaggaccccgccggggcggtgccggccgaaggccccgagggcgcgggcgcgcgt
ctgcgagagctgagggacaggctggagctggagctgctgcagcagggcgaggagcagtgc
gagtgtgtcctgaggtgcagggcgcagcaagtggccgagcaaatgaccaagatgatggag
ctggccagagagaaacaggctgcagagctgaagatcctcaaggagactttggagactgac
accaaggaggtgaagaaaaagctggaggccaagaggctggatcggatccaggccatgatg
aaggtcaccacagacaagatggctcaggagaggttgaagagagagattaacaactcccat
atccaggaggtggtgcaggtcatcaagcagatgacggagaacctggagaatcaccaggag
aagctggaagagaagcaggcagcctgcctggaacagatccgggagatggaaaagcagttc
cagcaggaggcgctggcacagtacgaggccaagatgaagggcctggaggtggaagtgaag
gagtcggtgaggacctacctcagggcctgcttgccctctgtggaggaggacaagcctgag
aggccctgcagggtctccagagagctgtgtgagcaggatgcactcacagagaagacagat
gcccaggagagcctcctccgatgcccccatgcccttgggatgttctgcaaagacattcac
ccttctctgggacctctctggatctcccagccacgtgccaccaggcccaaccctgctgag
ctggtgcaacgtgacaggcggggaggcggcgccgaggagttgctaacggggctgcagtac
tcccggatcttaaggcgcccgctccagtcgccgcgtctccgcaccgccagcttctcagcc
gccgggagctggcaggcgggcgcgttgtctcggatggagacgtccgagatacgagcgcgc
actcccccaccgccacccccgcgccgaatcagcgtgtgcgggaggaacaattgtgtgtgc
gtgcgtgattcgctacacttccagtggcggttcccagccagactgagagcccccaacccc
gcgcagcgtagctgcaccgatgggggcagccctcgtctttttcgacgggctcagggtccc
gccagtttctatggagccccgggcaccgactccggtgggggcggagggtggggagagaag
actgtgactttgggattggcccggtcgggtgcatgtggccccctgcgagcagcccccgcc
ccgtccccgctgccgcagccccagggaagcgcggaggagaagctgctccccgacgtcgtg
gcccaccgagaggtgggtgaaggtcaggggcggtctccgccgccccgtcagtttcggccc
tga

  All links  
Gene (52)   
   RefGene (49)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (63)   

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