KEGG   Mirounga angustirostris (Northern elephant seal): 123843366
Entry
123843366         CDS       T11530                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X3
  KO
K05459  insulin-like growth factor 1
Organism
mano  Mirounga angustirostris (Northern elephant seal)
Pathway
mano01521  EGFR tyrosine kinase inhibitor resistance
mano01522  Endocrine resistance
mano04010  MAPK signaling pathway
mano04014  Ras signaling pathway
mano04015  Rap1 signaling pathway
mano04066  HIF-1 signaling pathway
mano04068  FoxO signaling pathway
mano04081  Hormone signaling
mano04114  Oocyte meiosis
mano04115  p53 signaling pathway
mano04150  mTOR signaling pathway
mano04151  PI3K-Akt signaling pathway
mano04152  AMPK signaling pathway
mano04211  Longevity regulating pathway
mano04213  Longevity regulating pathway - multiple species
mano04510  Focal adhesion
mano04518  Integrin signaling
mano04550  Signaling pathways regulating pluripotency of stem cells
mano04730  Long-term depression
mano04750  Inflammatory mediator regulation of TRP channels
mano04913  Ovarian steroidogenesis
mano04914  Progesterone-mediated oocyte maturation
mano04935  Growth hormone synthesis, secretion and action
mano04960  Aldosterone-regulated sodium reabsorption
mano05200  Pathways in cancer
mano05202  Transcriptional misregulation in cancer
mano05205  Proteoglycans in cancer
mano05214  Glioma
mano05215  Prostate cancer
mano05218  Melanoma
mano05224  Breast cancer
mano05410  Hypertrophic cardiomyopathy
mano05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mano00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123843366 (IGF1)
   04014 Ras signaling pathway
    123843366 (IGF1)
   04015 Rap1 signaling pathway
    123843366 (IGF1)
   04066 HIF-1 signaling pathway
    123843366 (IGF1)
   04068 FoxO signaling pathway
    123843366 (IGF1)
   04151 PI3K-Akt signaling pathway
    123843366 (IGF1)
   04152 AMPK signaling pathway
    123843366 (IGF1)
   04150 mTOR signaling pathway
    123843366 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    123843366 (IGF1)
   04518 Integrin signaling
    123843366 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123843366 (IGF1)
   04115 p53 signaling pathway
    123843366 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123843366 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    123843366 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    123843366 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    123843366 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    123843366 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123843366 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    123843366 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123843366 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    123843366 (IGF1)
   04213 Longevity regulating pathway - multiple species
    123843366 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123843366 (IGF1)
   05202 Transcriptional misregulation in cancer
    123843366 (IGF1)
   05205 Proteoglycans in cancer
    123843366 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    123843366 (IGF1)
   05218 Melanoma
    123843366 (IGF1)
   05215 Prostate cancer
    123843366 (IGF1)
   05224 Breast cancer
    123843366 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    123843366 (IGF1)
   05414 Dilated cardiomyopathy
    123843366 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123843366 (IGF1)
   01522 Endocrine resistance
    123843366 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:mano04052]
    123843366 (IGF1)
Cytokines and neuropeptides [BR:mano04052]
 Cytokines
  Growth factors (RTK binding)
   123843366 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 123843366
NCBI-ProteinID: XP_045728686
Position
Unknown
AA seq 159 aa
MGKISSLPTQLFKCCFCDFLKVKMHIMSSSQLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYHPPSTTKKMKSQRRRKGSTFEERK
NT seq 480 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacattatgtcctcctctcagctcttctacctggccctgtgcttgctc
accttcaccagctccgccacggctggaccagagacgctctgtggggctgagctggtggac
gctcttcagttcgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcacctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatttgaggaggctagagatgtactgtgcacccctcaagcctgccaagtctgcccgctca
gtccgtgcccagcgccacaccgacatgcccaaggctcagaagtatcatcccccatctacc
accaagaaaatgaagtctcagaggagaaggaaaggaagtacatttgaagaacgcaagtag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (2)   
   Pfam (2)   
All databases (14)   

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