KEGG   Muscardinus avellanarius (hazel dormouse): 308277588
Entry
308277588         CDS       T11987                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform 1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mave  Muscardinus avellanarius (hazel dormouse)
Pathway
mave00562  Inositol phosphate metabolism
mave01100  Metabolic pathways
mave04015  Rap1 signaling pathway
mave04020  Calcium signaling pathway
mave04022  cGMP-PKG signaling pathway
mave04062  Chemokine signaling pathway
mave04070  Phosphatidylinositol signaling system
mave04071  Sphingolipid signaling pathway
mave04072  Phospholipase D signaling pathway
mave04081  Hormone signaling
mave04082  Neuroactive ligand signaling
mave04261  Adrenergic signaling in cardiomyocytes
mave04270  Vascular smooth muscle contraction
mave04310  Wnt signaling pathway
mave04371  Apelin signaling pathway
mave04540  Gap junction
mave04611  Platelet activation
mave04613  Neutrophil extracellular trap formation
mave04621  NOD-like receptor signaling pathway
mave04713  Circadian entrainment
mave04720  Long-term potentiation
mave04723  Retrograde endocannabinoid signaling
mave04724  Glutamatergic synapse
mave04725  Cholinergic synapse
mave04726  Serotonergic synapse
mave04728  Dopaminergic synapse
mave04730  Long-term depression
mave04742  Taste transduction
mave04750  Inflammatory mediator regulation of TRP channels
mave04911  Insulin secretion
mave04912  GnRH signaling pathway
mave04915  Estrogen signaling pathway
mave04916  Melanogenesis
mave04918  Thyroid hormone synthesis
mave04919  Thyroid hormone signaling pathway
mave04921  Oxytocin signaling pathway
mave04922  Glucagon signaling pathway
mave04924  Renin secretion
mave04925  Aldosterone synthesis and secretion
mave04926  Relaxin signaling pathway
mave04927  Cortisol synthesis and secretion
mave04928  Parathyroid hormone synthesis, secretion and action
mave04929  GnRH secretion
mave04933  AGE-RAGE signaling pathway in diabetic complications
mave04934  Cushing syndrome
mave04935  Growth hormone synthesis, secretion and action
mave04961  Endocrine and other factor-regulated calcium reabsorption
mave04970  Salivary secretion
mave04971  Gastric acid secretion
mave04972  Pancreatic secretion
mave04973  Carbohydrate digestion and absorption
mave05010  Alzheimer disease
mave05016  Huntington disease
mave05017  Spinocerebellar ataxia
mave05022  Pathways of neurodegeneration - multiple diseases
mave05142  Chagas disease
mave05143  African trypanosomiasis
mave05146  Amoebiasis
mave05163  Human cytomegalovirus infection
mave05200  Pathways in cancer
mave05415  Diabetic cardiomyopathy
mave05417  Lipid and atherosclerosis
Module
mave_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mave00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    308277588 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    308277588 (PLCB1)
   04310 Wnt signaling pathway
    308277588 (PLCB1)
   04371 Apelin signaling pathway
    308277588 (PLCB1)
   04020 Calcium signaling pathway
    308277588 (PLCB1)
   04070 Phosphatidylinositol signaling system
    308277588 (PLCB1)
   04072 Phospholipase D signaling pathway
    308277588 (PLCB1)
   04071 Sphingolipid signaling pathway
    308277588 (PLCB1)
   04022 cGMP-PKG signaling pathway
    308277588 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    308277588 (PLCB1)
   04081 Hormone signaling
    308277588 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    308277588 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    308277588 (PLCB1)
   04613 Neutrophil extracellular trap formation
    308277588 (PLCB1)
   04621 NOD-like receptor signaling pathway
    308277588 (PLCB1)
   04062 Chemokine signaling pathway
    308277588 (PLCB1)
  09152 Endocrine system
   04911 Insulin secretion
    308277588 (PLCB1)
   04922 Glucagon signaling pathway
    308277588 (PLCB1)
   04929 GnRH secretion
    308277588 (PLCB1)
   04912 GnRH signaling pathway
    308277588 (PLCB1)
   04915 Estrogen signaling pathway
    308277588 (PLCB1)
   04921 Oxytocin signaling pathway
    308277588 (PLCB1)
   04926 Relaxin signaling pathway
    308277588 (PLCB1)
   04935 Growth hormone synthesis, secretion and action
    308277588 (PLCB1)
   04918 Thyroid hormone synthesis
    308277588 (PLCB1)
   04919 Thyroid hormone signaling pathway
    308277588 (PLCB1)
   04928 Parathyroid hormone synthesis, secretion and action
    308277588 (PLCB1)
   04916 Melanogenesis
    308277588 (PLCB1)
   04924 Renin secretion
    308277588 (PLCB1)
   04925 Aldosterone synthesis and secretion
    308277588 (PLCB1)
   04927 Cortisol synthesis and secretion
    308277588 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    308277588 (PLCB1)
   04270 Vascular smooth muscle contraction
    308277588 (PLCB1)
  09154 Digestive system
   04970 Salivary secretion
    308277588 (PLCB1)
   04971 Gastric acid secretion
    308277588 (PLCB1)
   04972 Pancreatic secretion
    308277588 (PLCB1)
   04973 Carbohydrate digestion and absorption
    308277588 (PLCB1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    308277588 (PLCB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    308277588 (PLCB1)
   04725 Cholinergic synapse
    308277588 (PLCB1)
   04728 Dopaminergic synapse
    308277588 (PLCB1)
   04726 Serotonergic synapse
    308277588 (PLCB1)
   04720 Long-term potentiation
    308277588 (PLCB1)
   04730 Long-term depression
    308277588 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    308277588 (PLCB1)
  09157 Sensory system
   04742 Taste transduction
    308277588 (PLCB1)
   04750 Inflammatory mediator regulation of TRP channels
    308277588 (PLCB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    308277588 (PLCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    308277588 (PLCB1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    308277588 (PLCB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    308277588 (PLCB1)
   05142 Chagas disease
    308277588 (PLCB1)
   05143 African trypanosomiasis
    308277588 (PLCB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    308277588 (PLCB1)
   05016 Huntington disease
    308277588 (PLCB1)
   05017 Spinocerebellar ataxia
    308277588 (PLCB1)
   05022 Pathways of neurodegeneration - multiple diseases
    308277588 (PLCB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    308277588 (PLCB1)
   05415 Diabetic cardiomyopathy
    308277588 (PLCB1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    308277588 (PLCB1)
   04934 Cushing syndrome
    308277588 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mave04131]
    308277588 (PLCB1)
Enzymes [BR:mave01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     308277588 (PLCB1)
Membrane trafficking [BR:mave04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    308277588 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    308277588 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 308277588
NCBI-ProteinID: XP_080572962
Position
19:complement(<9334782..>10090809)
AA seq 1216 aa
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFYFYWTDQNKE
TELLDLSLVKDARCGKHARAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISYLNLV
AFQEEVAKEWTSEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLAKKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTCSDSSSVFEPSSPGAGEADTESDEDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYVSLRNER
NQPLVLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
EAEPGETPSETPSETRTTPAENGVNHTASLAPKPPPQALHSQPAPGSVKAPAKTEDLIQS
VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
RRRAALEKTAKKDSKKKSEPSSPDHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKQKEIRQQILDEKP
KLQTELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPPSLAPDPGKVNHKPSPS
EEGEGENPGKELDTPL
NT seq 3651 nt   +upstreamnt  +downstreamnt
atggctggggctcagcccggggtgcacgccttgcaactcaagccggtgtgcgtgtccgac
agtctcaagaagggcaccaaattcgtcaagtgggatgatgactctactattgttactcca
attattttgaggactgaccctcagggattttacttttactggacagatcaaaataaggag
acggagctgttagatctcagccttgtcaaggatgccaggtgtgggaagcatgccagagct
cccaaggaccccaagttgcgcgaacttctggatgtggggaatatcgggcgcctggagcat
cgcatgataaccgtggtgtacgggcctgacctcgtgaacatctcctatttgaatctcgtg
gctttccaagaagaagtggccaaggaatggacaagcgaggttttcagtttggcaacaaac
ctgctggcccaaaacatgtccagggacgcgtttctggaaaaagcctacacaaaactgaag
ctgcaagtcactccagaaggtcggattcctctcaaaaacatctaccgcttgttttcagca
gaccggaagcgagtggaaaccgcattagaggcttgcagccttccatcttcaaggaacgat
tcaatacctcaggaggacttcactccagacgtgtacagagttttcctgaacaatctttgc
cctcggcctgaaattgataacatcttttctgagttcggtgccaaaagcaaaccatatctt
actgtcgaccagatgatggattttatcaaccttaagcagagagatccccggctaaatgaa
atcctttacccacctctgaaacaagagcaagtccaagtattgattgagaagtatgaaccc
aacaacagcctcgccaaaaaaggacagatatccgtggatggattcatgcgttatctgagt
ggagaagaaaacggagtcgtttcccccgagaaactggatttgaacgaagacatgtctcag
cccctgtctcactatttcatcaattcctcacacaacacctacctcacagctgggcagctg
gctggaaactcctccgtggagatgtatcgccaggtgcttctgtctggctgtcgctgtgtg
gagctggactgctggaaggggaggaccgctgaagaggaacctgtcatcacccatggattc
accatgacaaccgaaatatccttcaaggaagtgatcgaagccatcgcagagtgcgccttc
aagacttcccccttcccaatcctcctgtcattcgagaaccacgtggactccccaaagcag
caagccaagatggcggagtattgccgactgatctttggggacgccctactcatggagcca
ctggaaaaatacccactggaatctggagttcctcttccgagccctatggatttaatgtat
aaaatcttggtgaagaacaagaagaaatcacacaagtcatcagaaggaagcggcaaaaag
aagctgtcagaacaagcctccaacacctgcagcgactcctccagcgtgtttgagccctcc
tccccgggagcgggggaggctgataccgaaagtgatgaggacgacgacgatgacgactgt
aaaaaatcttcaatggatgaggggactgctgggagcgaggccatggccacagaagagatg
tctaacctggtgaactatatccagccggtcaagttcgagtcatttgaaatttcaaaaaaa
agaaataaaagctttgaaatgtcttccttcgtggaaaccaaaggacttgagcaacttacg
aagtctccagtggaatttgtagaatataacaaaatgcagctgagcaggatctacccaaaa
gggacccgcgtggactcctccaactatatgcctcagctcttctggaacgcaggctgccag
atggtcgcgctcaacttccagacagtggacctggcgatgcagataaacatgggcatgtat
gaatacaatgggaagagtggctacaggttgaagccagaattcatgaggaggcccgacaag
cattttgatccattcaccgaaggcatcgtagacgggatagtggccaacactctatctgtc
aagattatttcaggtcagtttctttctgataagaaagttggaacttatgtagaagtggat
atgtttggtttgcctgtggacacaaggaggaaggcatttaagaccaagacatcccaagga
aacgctgtcaatcctgtctgggaagaagaaccaattgtgttcaaaaaggtggttcttcct
tccttggcttgtttaaggatagcagtttatgaagaaggaggtaaatttatcggccatcgg
atcttaccagtacaagccatccggccaggctatcactatgtctccctgaggaatgaaagg
aaccagccactggtactgccagctgtcttcgtctacatagaagtgaaagactatgtgcca
gatacatatgcagatgtgattgaagctttgtcaaacccaatccgatatgtaaatctgatg
gagcaaagagctaaacaactggctgctttgacattggaggatgaagaagaagtaaagaaa
gaggctgaacctggggaaacaccatcagagactccaagtgaaaccaggacaaccccagca
gaaaatggggtgaatcacactgcatccctggcaccaaaaccaccaccccaggctctgcac
agccagcccgccccaggttctgtgaaggcacctgccaaaacagaagatcttattcagagt
gtcttaacagaagtggaagcgcagaccattgaagagctaaagcagcagaagtcatttgta
aaacttcaaaagaagcactacaaagaaatgaaagacctggttaagaggcaccacaagaaa
actactgacctgatcaaagaacacactacaaaatataatgagattcagaatgactacttg
agaaggagggcagctctggagaagaccgccaagaaggacagcaagaaaaagtcagagccc
agcagccctgaccacggctcgtcagcaatcgagcaagacctggctgccctggatgctgaa
atgacccagaagctaatagacttgaaggacaaacaacagcagcagctgcttaatcttcgg
caagaacaatattacagtgaaaaataccagaagcgagaacacattaaactgctcattcaa
aagttgacagatgttgctgaagagtgtcagaacaaccaattaaagaagctcaaagaaatc
tgtgagaaagagaagaaggagttaaagaagaagatggataagaagaggcaagagaagata
acagaagctaaatccaaagacaaaagccagatggaagaggagaagacagagatgatccga
tcctacattcaggaggtggttcaatacatcaagaggttagaagaggcacaaagtaaacga
caagaaaagctcgtggagaaacagaaggagatccgccagcagatcctggatgagaagccc
aagctgcagacggagctggagcaagaataccaagacaagttcaaaagactgcccctggag
attttggaattcgtgcaggaagccatgaaaggaaagatcagtgaagacagcaatcatggc
tctgccccaccctccctggccccagaccctggaaaagtgaaccacaagccttcgcccagt
gaggagggggaaggagagaacccaggaaaagagttggatacccctctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (12)   

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