KEGG   Macaca fascicularis (crab-eating macaque): 102118497
Entry
102118497         CDS       T02918                                 

Gene name
MAPK9
Definition
(RefSeq) mitogen-activated protein kinase 9
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01522  Endocrine resistance
mcf04010  MAPK signaling pathway
mcf04012  ErbB signaling pathway
mcf04014  Ras signaling pathway
mcf04024  cAMP signaling pathway
mcf04068  FoxO signaling pathway
mcf04071  Sphingolipid signaling pathway
mcf04137  Mitophagy - animal
mcf04140  Autophagy - animal
mcf04141  Protein processing in endoplasmic reticulum
mcf04210  Apoptosis
mcf04215  Apoptosis - multiple species
mcf04217  Necroptosis
mcf04310  Wnt signaling pathway
mcf04380  Osteoclast differentiation
mcf04510  Focal adhesion
mcf04530  Tight junction
mcf04620  Toll-like receptor signaling pathway
mcf04621  NOD-like receptor signaling pathway
mcf04622  RIG-I-like receptor signaling pathway
mcf04625  C-type lectin receptor signaling pathway
mcf04657  IL-17 signaling pathway
mcf04658  Th1 and Th2 cell differentiation
mcf04659  Th17 cell differentiation
mcf04660  T cell receptor signaling pathway
mcf04664  Fc epsilon RI signaling pathway
mcf04668  TNF signaling pathway
mcf04722  Neurotrophin signaling pathway
mcf04723  Retrograde endocannabinoid signaling
mcf04728  Dopaminergic synapse
mcf04750  Inflammatory mediator regulation of TRP channels
mcf04910  Insulin signaling pathway
mcf04912  GnRH signaling pathway
mcf04914  Progesterone-mediated oocyte maturation
mcf04917  Prolactin signaling pathway
mcf04920  Adipocytokine signaling pathway
mcf04926  Relaxin signaling pathway
mcf04930  Type II diabetes mellitus
mcf04931  Insulin resistance
mcf04932  Non-alcoholic fatty liver disease
mcf04933  AGE-RAGE signaling pathway in diabetic complications
mcf04935  Growth hormone synthesis, secretion and action
mcf05010  Alzheimer disease
mcf05012  Parkinson disease
mcf05016  Huntington disease
mcf05017  Spinocerebellar ataxia
mcf05020  Prion disease
mcf05022  Pathways of neurodegeneration - multiple diseases
mcf05132  Salmonella infection
mcf05133  Pertussis
mcf05135  Yersinia infection
mcf05142  Chagas disease
mcf05145  Toxoplasmosis
mcf05152  Tuberculosis
mcf05161  Hepatitis B
mcf05162  Measles
mcf05166  Human T-cell leukemia virus 1 infection
mcf05167  Kaposi sarcoma-associated herpesvirus infection
mcf05169  Epstein-Barr virus infection
mcf05170  Human immunodeficiency virus 1 infection
mcf05171  Coronavirus disease - COVID-19
mcf05200  Pathways in cancer
mcf05210  Colorectal cancer
mcf05212  Pancreatic cancer
mcf05231  Choline metabolism in cancer
mcf05415  Diabetic cardiomyopathy
mcf05417  Lipid and atherosclerosis
mcf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102118497 (MAPK9)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102118497 (MAPK9)
   04012 ErbB signaling pathway
    102118497 (MAPK9)
   04014 Ras signaling pathway
    102118497 (MAPK9)
   04310 Wnt signaling pathway
    102118497 (MAPK9)
   04668 TNF signaling pathway
    102118497 (MAPK9)
   04068 FoxO signaling pathway
    102118497 (MAPK9)
   04071 Sphingolipid signaling pathway
    102118497 (MAPK9)
   04024 cAMP signaling pathway
    102118497 (MAPK9)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102118497 (MAPK9)
   04137 Mitophagy - animal
    102118497 (MAPK9)
  09143 Cell growth and death
   04210 Apoptosis
    102118497 (MAPK9)
   04215 Apoptosis - multiple species
    102118497 (MAPK9)
   04217 Necroptosis
    102118497 (MAPK9)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102118497 (MAPK9)
   04530 Tight junction
    102118497 (MAPK9)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102118497 (MAPK9)
   04621 NOD-like receptor signaling pathway
    102118497 (MAPK9)
   04622 RIG-I-like receptor signaling pathway
    102118497 (MAPK9)
   04625 C-type lectin receptor signaling pathway
    102118497 (MAPK9)
   04660 T cell receptor signaling pathway
    102118497 (MAPK9)
   04658 Th1 and Th2 cell differentiation
    102118497 (MAPK9)
   04659 Th17 cell differentiation
    102118497 (MAPK9)
   04657 IL-17 signaling pathway
    102118497 (MAPK9)
   04664 Fc epsilon RI signaling pathway
    102118497 (MAPK9)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102118497 (MAPK9)
   04920 Adipocytokine signaling pathway
    102118497 (MAPK9)
   04912 GnRH signaling pathway
    102118497 (MAPK9)
   04914 Progesterone-mediated oocyte maturation
    102118497 (MAPK9)
   04917 Prolactin signaling pathway
    102118497 (MAPK9)
   04926 Relaxin signaling pathway
    102118497 (MAPK9)
   04935 Growth hormone synthesis, secretion and action
    102118497 (MAPK9)
  09156 Nervous system
   04728 Dopaminergic synapse
    102118497 (MAPK9)
   04723 Retrograde endocannabinoid signaling
    102118497 (MAPK9)
   04722 Neurotrophin signaling pathway
    102118497 (MAPK9)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102118497 (MAPK9)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102118497 (MAPK9)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102118497 (MAPK9)
   05231 Choline metabolism in cancer
    102118497 (MAPK9)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102118497 (MAPK9)
   05212 Pancreatic cancer
    102118497 (MAPK9)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102118497 (MAPK9)
   05170 Human immunodeficiency virus 1 infection
    102118497 (MAPK9)
   05161 Hepatitis B
    102118497 (MAPK9)
   05171 Coronavirus disease - COVID-19
    102118497 (MAPK9)
   05162 Measles
    102118497 (MAPK9)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102118497 (MAPK9)
   05169 Epstein-Barr virus infection
    102118497 (MAPK9)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102118497 (MAPK9)
   05135 Yersinia infection
    102118497 (MAPK9)
   05133 Pertussis
    102118497 (MAPK9)
   05152 Tuberculosis
    102118497 (MAPK9)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102118497 (MAPK9)
   05142 Chagas disease
    102118497 (MAPK9)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102118497 (MAPK9)
   05012 Parkinson disease
    102118497 (MAPK9)
   05016 Huntington disease
    102118497 (MAPK9)
   05017 Spinocerebellar ataxia
    102118497 (MAPK9)
   05020 Prion disease
    102118497 (MAPK9)
   05022 Pathways of neurodegeneration - multiple diseases
    102118497 (MAPK9)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102118497 (MAPK9)
   05418 Fluid shear stress and atherosclerosis
    102118497 (MAPK9)
   05415 Diabetic cardiomyopathy
    102118497 (MAPK9)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102118497 (MAPK9)
   04932 Non-alcoholic fatty liver disease
    102118497 (MAPK9)
   04931 Insulin resistance
    102118497 (MAPK9)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102118497 (MAPK9)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102118497 (MAPK9)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    102118497 (MAPK9)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102118497 (MAPK9)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102118497 (MAPK9)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo Kinase-like RIO1 APH FTA2
Other DBs
NCBI-GeneID: 102118497
NCBI-ProteinID: XP_005558857
UniProt: G7P735
Position
6
AA seq 424 aa
MSDGKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMAEMVLHKVLFPGRDYIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR
NT seq 1275 nt   +upstreamnt  +downstreamnt
atgagcgacggtaaatgtgacagtcagttttacagtgtgcaagtggcagactcaaccttc
actgtcctaaaacgttaccagcagctgaaaccaattggctctggggcccaagggattgtt
tgtgctgcatttgatacagttcttgggataaatgttgcagtcaagaaactaagccgtcct
tttcagaaccaaactcatgcaaagagagcttatcgtgaactcgtcctcttaaaatgtgtc
aatcataaaaatattattagtttgttaaatgtgtttacaccacaaaaaactctagaagaa
tttcaagatgtgtatctggttatggagttaatggatgctaacttatgtcaggttattcac
atggagctggatcatgaaagaatgtcctaccttctttaccagatgctttgtggtattaaa
catctgcattcagctggtataattcatagagatttgaagcctagcaacatcgttgtgaaa
tcagactgcaccctgaagatccttgactttggcctggcccggacggcctgcaccaacttc
atgatgaccccttacgtggtgacccggtactaccgggcacccgaagtcatcctgggtatg
ggctacaaagagaacgtggacatctggtctgtcgggtgcatcatggcagaaatggtcctc
cataaagtcctgttcccaggaagagactatattgatcagtggaataaagttattgagcag
cttggaacaccatcagcagagttcatgaagaaactgcagccgactgtgaggaattatgta
gaaaacagaccaaagtatcctggaatcaaattcgaagaactctttccagactggatattc
ccatcagagtctgagcgagacaaaataaaaaccagtcaagccagagatctgttatcgaaa
atgctagtgattgatcctgacaagcggatctctgtagacgaagctctgcgtcacccgtac
atcactgtctggtatgacccggccgaagcagaggcaccaccacctcagatttatgatgcc
cagttggaagaaagagaacatgcaattgaagaatggaaagagctaatttacaaagaagtc
atggattgggaagaaagaagcaagaatggtgttgtaaaagatcagccttcagatgcagca
gtaagtagcaacgccactccttctcagtcttcatctatcaatgacatttcatccatgtcc
actgagcagacactggcctcagacacagacagcagtcttgatgcctcgacgggacccctt
gaaggttgtcgatga

KEGG   Macaca fascicularis (crab-eating macaque): 102121272
Entry
102121272         CDS       T02918                                 

Gene name
MAPK10
Definition
(RefSeq) mitogen-activated protein kinase 10
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01522  Endocrine resistance
mcf04010  MAPK signaling pathway
mcf04012  ErbB signaling pathway
mcf04014  Ras signaling pathway
mcf04024  cAMP signaling pathway
mcf04068  FoxO signaling pathway
mcf04071  Sphingolipid signaling pathway
mcf04137  Mitophagy - animal
mcf04140  Autophagy - animal
mcf04141  Protein processing in endoplasmic reticulum
mcf04210  Apoptosis
mcf04215  Apoptosis - multiple species
mcf04217  Necroptosis
mcf04310  Wnt signaling pathway
mcf04380  Osteoclast differentiation
mcf04510  Focal adhesion
mcf04530  Tight junction
mcf04620  Toll-like receptor signaling pathway
mcf04621  NOD-like receptor signaling pathway
mcf04622  RIG-I-like receptor signaling pathway
mcf04625  C-type lectin receptor signaling pathway
mcf04657  IL-17 signaling pathway
mcf04658  Th1 and Th2 cell differentiation
mcf04659  Th17 cell differentiation
mcf04660  T cell receptor signaling pathway
mcf04664  Fc epsilon RI signaling pathway
mcf04668  TNF signaling pathway
mcf04722  Neurotrophin signaling pathway
mcf04723  Retrograde endocannabinoid signaling
mcf04728  Dopaminergic synapse
mcf04750  Inflammatory mediator regulation of TRP channels
mcf04910  Insulin signaling pathway
mcf04912  GnRH signaling pathway
mcf04914  Progesterone-mediated oocyte maturation
mcf04917  Prolactin signaling pathway
mcf04920  Adipocytokine signaling pathway
mcf04926  Relaxin signaling pathway
mcf04930  Type II diabetes mellitus
mcf04931  Insulin resistance
mcf04932  Non-alcoholic fatty liver disease
mcf04933  AGE-RAGE signaling pathway in diabetic complications
mcf04935  Growth hormone synthesis, secretion and action
mcf05010  Alzheimer disease
mcf05012  Parkinson disease
mcf05016  Huntington disease
mcf05017  Spinocerebellar ataxia
mcf05020  Prion disease
mcf05022  Pathways of neurodegeneration - multiple diseases
mcf05132  Salmonella infection
mcf05133  Pertussis
mcf05135  Yersinia infection
mcf05142  Chagas disease
mcf05145  Toxoplasmosis
mcf05152  Tuberculosis
mcf05161  Hepatitis B
mcf05162  Measles
mcf05166  Human T-cell leukemia virus 1 infection
mcf05167  Kaposi sarcoma-associated herpesvirus infection
mcf05169  Epstein-Barr virus infection
mcf05170  Human immunodeficiency virus 1 infection
mcf05171  Coronavirus disease - COVID-19
mcf05200  Pathways in cancer
mcf05210  Colorectal cancer
mcf05212  Pancreatic cancer
mcf05231  Choline metabolism in cancer
mcf05415  Diabetic cardiomyopathy
mcf05417  Lipid and atherosclerosis
mcf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102121272 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102121272 (MAPK10)
   04012 ErbB signaling pathway
    102121272 (MAPK10)
   04014 Ras signaling pathway
    102121272 (MAPK10)
   04310 Wnt signaling pathway
    102121272 (MAPK10)
   04668 TNF signaling pathway
    102121272 (MAPK10)
   04068 FoxO signaling pathway
    102121272 (MAPK10)
   04071 Sphingolipid signaling pathway
    102121272 (MAPK10)
   04024 cAMP signaling pathway
    102121272 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102121272 (MAPK10)
   04137 Mitophagy - animal
    102121272 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    102121272 (MAPK10)
   04215 Apoptosis - multiple species
    102121272 (MAPK10)
   04217 Necroptosis
    102121272 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102121272 (MAPK10)
   04530 Tight junction
    102121272 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102121272 (MAPK10)
   04621 NOD-like receptor signaling pathway
    102121272 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    102121272 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    102121272 (MAPK10)
   04660 T cell receptor signaling pathway
    102121272 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    102121272 (MAPK10)
   04659 Th17 cell differentiation
    102121272 (MAPK10)
   04657 IL-17 signaling pathway
    102121272 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    102121272 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102121272 (MAPK10)
   04920 Adipocytokine signaling pathway
    102121272 (MAPK10)
   04912 GnRH signaling pathway
    102121272 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    102121272 (MAPK10)
   04917 Prolactin signaling pathway
    102121272 (MAPK10)
   04926 Relaxin signaling pathway
    102121272 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    102121272 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    102121272 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    102121272 (MAPK10)
   04722 Neurotrophin signaling pathway
    102121272 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102121272 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102121272 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102121272 (MAPK10)
   05231 Choline metabolism in cancer
    102121272 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102121272 (MAPK10)
   05212 Pancreatic cancer
    102121272 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102121272 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    102121272 (MAPK10)
   05161 Hepatitis B
    102121272 (MAPK10)
   05171 Coronavirus disease - COVID-19
    102121272 (MAPK10)
   05162 Measles
    102121272 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102121272 (MAPK10)
   05169 Epstein-Barr virus infection
    102121272 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102121272 (MAPK10)
   05135 Yersinia infection
    102121272 (MAPK10)
   05133 Pertussis
    102121272 (MAPK10)
   05152 Tuberculosis
    102121272 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102121272 (MAPK10)
   05142 Chagas disease
    102121272 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102121272 (MAPK10)
   05012 Parkinson disease
    102121272 (MAPK10)
   05016 Huntington disease
    102121272 (MAPK10)
   05017 Spinocerebellar ataxia
    102121272 (MAPK10)
   05020 Prion disease
    102121272 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    102121272 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102121272 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    102121272 (MAPK10)
   05415 Diabetic cardiomyopathy
    102121272 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102121272 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    102121272 (MAPK10)
   04931 Insulin resistance
    102121272 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102121272 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102121272 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    102121272 (MAPK10)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102121272 (MAPK10)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102121272 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 Kinase-like RIO1 APH FTA2 TCAD9
Other DBs
NCBI-GeneID: 102121272
NCBI-ProteinID: XP_005555397
Position
5
AA seq 494 aa
MSRCCHEERERERERERLSLCYQCLNLEVFMSLHFLYYCSEPTLDVKIAFCQGFDKQVDV
SYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNV
AIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMD
ANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGL
ARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYID
QWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKAS
QARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEW
KELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTD
SSLEASAGPLGCCR
NT seq 1485 nt   +upstreamnt  +downstreamnt
atgtcaagatgctgtcatgaagagagagagagagagagagagagagagagactcagtctt
tgctatcagtgtctgaacttagaggtatttatgagcctccatttcttatactactgcagt
gaaccaacattggatgtgaaaattgccttttgtcagggattcgataaacaagtggatgtg
tcatatattgccaaacattacaacatgagcaaaagcaaagttgacaaccaattctacagt
gtggaagtgggagactcaaccttcacagttctcaagcgctaccagaatctaaagcctatt
ggctctggggctcagggcatagtttgtgccgcgtatgatgctgtccttgacagaaatgtg
gccattaagaagctcagcagaccctttcagaaccaaacccatgccaagagagcgtaccgg
gagctggtcctcatgaagtgtgtgaaccataaaaacattattagtttattaaatgtcttc
acaccccagaaaacgctggaggagttccaagatgtttacttagtaatggaactgatggat
gccaacttatgtcaagtgattcagatggaattagaccacgagcgaatgtcttacctgctg
taccaaatgctgtgtggcattaagcacctccactctgctggaattattcacagggattta
aaaccaagtaacattgtagtcaagtctgattgcacattgaaaatcctggactttggactg
gccaggacagcaggcacaagcttcatgatgactccatatgtggtgacacgttattacaga
gccccggaggtcatcctggggatgggctacaaggagaacgtggatatatggtctgtggga
tgcattatgggagaaatggttcgccacaaaatcctctttccaggaagggactatattgac
cagtggaataaggtaattgaacaactaggaacaccatgtccagaattcatgaagaaattg
caacccacagtaagaaactatgtggagaatcgacccaagtatgcgggactcaccttcccc
aagctcttcccagattccctcttcccagcggactccgagcacaataaactcaaagccagc
caagccagggacttgttgtcaaagatgctagtgattgacccagcaaaaagaatatcagtg
gacgacgccttacagcatccctacatcaacgtctggtatgacccagctgaagtggaggcg
cctccacctcagatatatgacaagcagttggatgaaagagaacacacaattgaagaatgg
aaagaacttatctacaaggaagtaatgaactcagaagagaagactaaaaatggcgtagta
aaaggacagccttctccttcaggtgcagcagtgaacagcagtgagagtctccctccatcc
tcgtctgtcaatgacatctcctccatgtccaccgaccagaccctggcatctgacactgac
agcagcctggaagcttcggcaggacccctgggttgttgcaggtga

KEGG   Macaca fascicularis (crab-eating macaque): 102126339
Entry
102126339         CDS       T02918                                 

Gene name
MAPK8
Definition
(RefSeq) mitogen-activated protein kinase 8
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01522  Endocrine resistance
mcf04010  MAPK signaling pathway
mcf04012  ErbB signaling pathway
mcf04014  Ras signaling pathway
mcf04024  cAMP signaling pathway
mcf04068  FoxO signaling pathway
mcf04071  Sphingolipid signaling pathway
mcf04137  Mitophagy - animal
mcf04140  Autophagy - animal
mcf04141  Protein processing in endoplasmic reticulum
mcf04210  Apoptosis
mcf04215  Apoptosis - multiple species
mcf04217  Necroptosis
mcf04310  Wnt signaling pathway
mcf04380  Osteoclast differentiation
mcf04510  Focal adhesion
mcf04530  Tight junction
mcf04620  Toll-like receptor signaling pathway
mcf04621  NOD-like receptor signaling pathway
mcf04622  RIG-I-like receptor signaling pathway
mcf04625  C-type lectin receptor signaling pathway
mcf04657  IL-17 signaling pathway
mcf04658  Th1 and Th2 cell differentiation
mcf04659  Th17 cell differentiation
mcf04660  T cell receptor signaling pathway
mcf04664  Fc epsilon RI signaling pathway
mcf04668  TNF signaling pathway
mcf04722  Neurotrophin signaling pathway
mcf04723  Retrograde endocannabinoid signaling
mcf04728  Dopaminergic synapse
mcf04750  Inflammatory mediator regulation of TRP channels
mcf04910  Insulin signaling pathway
mcf04912  GnRH signaling pathway
mcf04914  Progesterone-mediated oocyte maturation
mcf04917  Prolactin signaling pathway
mcf04920  Adipocytokine signaling pathway
mcf04926  Relaxin signaling pathway
mcf04930  Type II diabetes mellitus
mcf04931  Insulin resistance
mcf04932  Non-alcoholic fatty liver disease
mcf04933  AGE-RAGE signaling pathway in diabetic complications
mcf04935  Growth hormone synthesis, secretion and action
mcf05010  Alzheimer disease
mcf05012  Parkinson disease
mcf05016  Huntington disease
mcf05017  Spinocerebellar ataxia
mcf05020  Prion disease
mcf05022  Pathways of neurodegeneration - multiple diseases
mcf05132  Salmonella infection
mcf05133  Pertussis
mcf05135  Yersinia infection
mcf05142  Chagas disease
mcf05145  Toxoplasmosis
mcf05152  Tuberculosis
mcf05161  Hepatitis B
mcf05162  Measles
mcf05166  Human T-cell leukemia virus 1 infection
mcf05167  Kaposi sarcoma-associated herpesvirus infection
mcf05169  Epstein-Barr virus infection
mcf05170  Human immunodeficiency virus 1 infection
mcf05171  Coronavirus disease - COVID-19
mcf05200  Pathways in cancer
mcf05210  Colorectal cancer
mcf05212  Pancreatic cancer
mcf05231  Choline metabolism in cancer
mcf05415  Diabetic cardiomyopathy
mcf05417  Lipid and atherosclerosis
mcf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102126339 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102126339 (MAPK8)
   04012 ErbB signaling pathway
    102126339 (MAPK8)
   04014 Ras signaling pathway
    102126339 (MAPK8)
   04310 Wnt signaling pathway
    102126339 (MAPK8)
   04668 TNF signaling pathway
    102126339 (MAPK8)
   04068 FoxO signaling pathway
    102126339 (MAPK8)
   04071 Sphingolipid signaling pathway
    102126339 (MAPK8)
   04024 cAMP signaling pathway
    102126339 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102126339 (MAPK8)
   04137 Mitophagy - animal
    102126339 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    102126339 (MAPK8)
   04215 Apoptosis - multiple species
    102126339 (MAPK8)
   04217 Necroptosis
    102126339 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102126339 (MAPK8)
   04530 Tight junction
    102126339 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102126339 (MAPK8)
   04621 NOD-like receptor signaling pathway
    102126339 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    102126339 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    102126339 (MAPK8)
   04660 T cell receptor signaling pathway
    102126339 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    102126339 (MAPK8)
   04659 Th17 cell differentiation
    102126339 (MAPK8)
   04657 IL-17 signaling pathway
    102126339 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    102126339 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102126339 (MAPK8)
   04920 Adipocytokine signaling pathway
    102126339 (MAPK8)
   04912 GnRH signaling pathway
    102126339 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    102126339 (MAPK8)
   04917 Prolactin signaling pathway
    102126339 (MAPK8)
   04926 Relaxin signaling pathway
    102126339 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    102126339 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    102126339 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    102126339 (MAPK8)
   04722 Neurotrophin signaling pathway
    102126339 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102126339 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102126339 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102126339 (MAPK8)
   05231 Choline metabolism in cancer
    102126339 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102126339 (MAPK8)
   05212 Pancreatic cancer
    102126339 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102126339 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    102126339 (MAPK8)
   05161 Hepatitis B
    102126339 (MAPK8)
   05171 Coronavirus disease - COVID-19
    102126339 (MAPK8)
   05162 Measles
    102126339 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102126339 (MAPK8)
   05169 Epstein-Barr virus infection
    102126339 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102126339 (MAPK8)
   05135 Yersinia infection
    102126339 (MAPK8)
   05133 Pertussis
    102126339 (MAPK8)
   05152 Tuberculosis
    102126339 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102126339 (MAPK8)
   05142 Chagas disease
    102126339 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102126339 (MAPK8)
   05012 Parkinson disease
    102126339 (MAPK8)
   05016 Huntington disease
    102126339 (MAPK8)
   05017 Spinocerebellar ataxia
    102126339 (MAPK8)
   05020 Prion disease
    102126339 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    102126339 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102126339 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    102126339 (MAPK8)
   05415 Diabetic cardiomyopathy
    102126339 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102126339 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    102126339 (MAPK8)
   04931 Insulin resistance
    102126339 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102126339 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102126339 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    102126339 (MAPK8)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     102126339 (MAPK8)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   102126339 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 Kinase-like RIO1 APH FTA2 DUF530 TCAD9
Other DBs
NCBI-GeneID: 102126339
NCBI-ProteinID: XP_005565231
UniProt: A0A2K5WLG9 G7PEU4
Position
9
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggctcaggagcgcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccgacca
tttcagaatcagactcatgccaagcgggcctacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tctgactgcactttgaagattcttgacttcggtctggccaggactgcaggaacgagtttt
atgatgacgccttacgtagtgactcgctactacagagcacccgaggtcatccttggcatg
ggctacaaggaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgtcctgaattcatgaagaaactgcaaccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagcttcgagaaactcttccctgatgtacttttc
ccagctgactcggaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaatagatgcatctaaaaggatctctgtagatgaagctctccaacacccgtac
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatccctgacaag
cagttagatgaaagggaacacacaatagaagagtggaaagaattgatatataaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcgtcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
gggcctctgggctgctgtagatga

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