KEGG   Macaca fascicularis (crab-eating macaque): 102137242
Entry
102137242         CDS       T02918                                 

Gene name
KIT
Definition
(RefSeq) KIT proto-oncogene receptor tyrosine kinase
  KO
K05091  proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf04010  MAPK signaling pathway
mcf04014  Ras signaling pathway
mcf04015  Rap1 signaling pathway
mcf04072  Phospholipase D signaling pathway
mcf04151  PI3K-Akt signaling pathway
mcf04640  Hematopoietic cell lineage
mcf04916  Melanogenesis
mcf05200  Pathways in cancer
mcf05221  Acute myeloid leukemia
mcf05224  Breast cancer
mcf05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102137242 (KIT)
   04014 Ras signaling pathway
    102137242 (KIT)
   04015 Rap1 signaling pathway
    102137242 (KIT)
   04072 Phospholipase D signaling pathway
    102137242 (KIT)
   04151 PI3K-Akt signaling pathway
    102137242 (KIT)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    102137242 (KIT)
  09152 Endocrine system
   04916 Melanogenesis
    102137242 (KIT)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102137242 (KIT)
   05230 Central carbon metabolism in cancer
    102137242 (KIT)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    102137242 (KIT)
   05224 Breast cancer
    102137242 (KIT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    102137242 (KIT)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mcf04090]
    102137242 (KIT)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102137242 (KIT)
Protein kinases [BR:mcf01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   102137242 (KIT)
CD molecules [BR:mcf04090]
 Proteins
  102137242 (KIT)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 CshA_NR2 Ig_4 V-set Ig_6 Pkinase_fungal APH C1-set
Other DBs
NCBI-GeneID: 102137242
NCBI-ProteinID: XP_005555329
Position
5
AA seq 977 aa
MRGARGAWDFLCVLLFLLHVQTGSSQPSVSPGEPSPPSIHPAKSELIVRVGNEIRLLCID
PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSSSIYVFVRDPAKLFLV
DRSLYGKEDNDTLVRCPLTDPEVTSYSLKGCQGKPLPKDLRFVPDPKAGITIKSVKRAYH
RLCLHCSADQEGKSVLSDKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
SVYSTWKRENSQQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNASIAFNVYVNTKPEILTYD
RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNASGPPFGKLVVQSSID
SSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCII
VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
CTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAESALYKNLLHSKESSCSDSTN
EYMDMKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKG
MAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPE
SIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEM
YDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINS
VGSTASSSQPLLVHDDV
NT seq 2934 nt   +upstreamnt  +downstreamnt
atgagaggcgctcgcggcgcctgggattttctctgcgttctgctcttcctgctccacgtc
cagacaggctcttctcaaccatctgtgagtccaggggaaccgtctccaccatccatccat
ccagcaaaatcagagttaatagtccgcgtgggcaacgagattaggctgttgtgcattgat
ccaggctttgtcaaatggacttttgagatcctggatgaaacgaatgagaataagcagaat
gaatggatcacagaaaaggcagaggccaccaacaccggcaaatacacgtgcaccaacaaa
cacggcttaagcagttccatttatgtgtttgttagagatcctgccaagcttttccttgtt
gaccgctccttgtatgggaaagaagacaatgacacactggtccgctgtcctctcacagac
ccagaagtgaccagttattccctcaaggggtgccaggggaagcctcttcccaaggacttg
aggtttgttcctgaccccaaggctggcatcacgatcaaaagcgtgaaacgcgcctaccat
cggctctgtctgcattgttccgcggaccaggagggcaagtcagtgctgtcggacaagttc
atcctgaaagtgaggccagccttcaaagctgtgcctgttgtgtctgtttccaaagcaagc
tatcttcttagggaaggggaagaattcacagtgacatgcacaataaaagatgtgtctagt
tctgtgtactcaacgtggaaaagagaaaacagtcagcagactaaactacaggagaaatat
aatagctggcatcacggtgacttcaattatgaacgtcaggcaacgttgactatcagttca
gcgagagttaatgattctggagtgttcatgtgttatgccaataatacttttggatcagca
aatgtcacaacaaccttggaagtagtagataaaggattcattaatatcttccccatgata
aacactacagtatttgtaaacgatggagaaaatgtagatttgattgttgaatatgaggca
ttccccaaacctgaacaccagcagtggatctatatgaacagaaccttcactgataaatgg
gaagattatcccaagtctgagaatgaaagtaatatcagatacgtaagtgaacttcatcta
accagattaaaaggcactgaaggaggcacttacacattcctagtgtccaattctgacgtc
aatgcttccatagcatttaatgtttatgtgaatacaaaaccagaaatcctgacttacgac
aggctcgtgaatggcatgctccaatgtgtggcagcaggattcccagaacccacaatagat
tggtatttttgtccgggaactgagcagagatgctctgcttctgtactgccagtggatgtg
cagacactaaacgcatctgggccaccgtttggaaaactagtggttcagagttccatagat
tctagtgcattcaagcacaatggcacggttgaatgtaaggcttacaacgatgtgggcaag
acttctgcctattttaactttgcatttaaaggtaacaacaaagagcaaatccatccccac
accctgttcactcctttgctgattggttttgtaatcgtagctggcatgatgtgcattatt
gtgatgattctcacctacaaatatttacagaaacccatgtatgaagtacagtggaaggtt
gttgaggagataaatggaaacaattacgtttacatagacccaacacaacttccttatgat
cacaaatgggagtttcccagaaacaggctgagttttgggaaaaccctgggtgctggcgct
tttgggaaggttgttgaggcaactgcttatggcttaattaagtcggacgcggccatgact
gtcgctgtaaagatgctcaaaccaagtgcccatttaacagaacgagaagccctcatgtct
gaactcaaagtcctgagttaccttggtaatcatatgaatattgtgaatcttcttggagcc
tgcaccattggagggcccaccctggtcattacagaatattgttgctatggtgatcttttg
aattttttgagaagaaaacgtgattcttttatttgttcaaagcaggaagatcatgcagaa
tctgcactttataagaatcttctgcattcaaaggagtcttcctgcagcgatagtactaat
gagtacatggacatgaaacctggagtttcttatgttgtcccaaccaaggctgacaaaagg
agatctgcgagaataggctcatatatagaaagagatgtgacacccgccatcatggaggat
gacgagttggctttagacttagaagacttgctgagcttttcttaccaggtggcaaagggc
atggctttccttgcctccaagaattgtattcacagagacttggcagccagaaatatcctc
cttactcatggtcggatcacaaagatttgtgattttggcctagccagagacatcaagaat
gattctaattatgtggttaaaggaaacgctcgactacctgtgaagtggatggcacctgaa
agcattttcaactgtgtgtacacatttgaaagtgacgtctggtcctatgggatttttctt
tgggagctattctctttaggaagcagcccctatcctggaatgccagtcgattctaaattc
tacaagatgatcaaggaaggcttccggatgctcagccctgaacatgcacctgctgaaatg
tatgacataatgaagacttgctgggatgcggatcccctaaaaagaccaacattcaagcaa
attgttcagctaattgagaagcagatttcagagagcaccaatcatatttactccaactta
gcaaactgcagccccaaccgacagaagcctgtagtggaccattccgtgcggatcaattct
gtcggcagcaccgcttcctcctcccaacctctgcttgtgcacgacgacgtctga

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