KEGG   Monodelphis domestica (gray short-tailed opossum): 100010279
Entry
100010279         CDS       T01031                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo01522  Endocrine resistance
mdo04010  MAPK signaling pathway
mdo04015  Rap1 signaling pathway
mdo04068  FoxO signaling pathway
mdo04071  Sphingolipid signaling pathway
mdo04114  Oocyte meiosis
mdo04148  Efferocytosis
mdo04218  Cellular senescence
mdo04261  Adrenergic signaling in cardiomyocytes
mdo04370  VEGF signaling pathway
mdo04380  Osteoclast differentiation
mdo04517  IgSF CAM signaling
mdo04519  Cadherin signaling
mdo04550  Signaling pathways regulating pluripotency of stem cells
mdo04611  Platelet activation
mdo04613  Neutrophil extracellular trap formation
mdo04620  Toll-like receptor signaling pathway
mdo04621  NOD-like receptor signaling pathway
mdo04622  RIG-I-like receptor signaling pathway
mdo04625  C-type lectin receptor signaling pathway
mdo04657  IL-17 signaling pathway
mdo04658  Th1 and Th2 cell differentiation
mdo04659  Th17 cell differentiation
mdo04660  T cell receptor signaling pathway
mdo04664  Fc epsilon RI signaling pathway
mdo04668  TNF signaling pathway
mdo04670  Leukocyte transendothelial migration
mdo04714  Thermogenesis
mdo04722  Neurotrophin signaling pathway
mdo04723  Retrograde endocannabinoid signaling
mdo04728  Dopaminergic synapse
mdo04750  Inflammatory mediator regulation of TRP channels
mdo04912  GnRH signaling pathway
mdo04914  Progesterone-mediated oocyte maturation
mdo04917  Prolactin signaling pathway
mdo04926  Relaxin signaling pathway
mdo04932  Non-alcoholic fatty liver disease
mdo04933  AGE-RAGE signaling pathway in diabetic complications
mdo04935  Growth hormone synthesis, secretion and action
mdo04936  Alcoholic liver disease
mdo05014  Amyotrophic lateral sclerosis
mdo05020  Prion disease
mdo05022  Pathways of neurodegeneration - multiple diseases
mdo05132  Salmonella infection
mdo05133  Pertussis
mdo05135  Yersinia infection
mdo05140  Leishmaniasis
mdo05142  Chagas disease
mdo05145  Toxoplasmosis
mdo05152  Tuberculosis
mdo05161  Hepatitis B
mdo05163  Human cytomegalovirus infection
mdo05167  Kaposi sarcoma-associated herpesvirus infection
mdo05169  Epstein-Barr virus infection
mdo05170  Human immunodeficiency virus 1 infection
mdo05171  Coronavirus disease
mdo05205  Proteoglycans in cancer
mdo05208  Chemical carcinogenesis - reactive oxygen species
mdo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mdo05415  Diabetic cardiomyopathy
mdo05417  Lipid and atherosclerosis
mdo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100010279 (MAPK12)
   04015 Rap1 signaling pathway
    100010279 (MAPK12)
   04370 VEGF signaling pathway
    100010279 (MAPK12)
   04668 TNF signaling pathway
    100010279 (MAPK12)
   04068 FoxO signaling pathway
    100010279 (MAPK12)
   04071 Sphingolipid signaling pathway
    100010279 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    100010279 (MAPK12)
   04519 Cadherin signaling
    100010279 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100010279 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100010279 (MAPK12)
   04218 Cellular senescence
    100010279 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100010279 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100010279 (MAPK12)
   04613 Neutrophil extracellular trap formation
    100010279 (MAPK12)
   04620 Toll-like receptor signaling pathway
    100010279 (MAPK12)
   04621 NOD-like receptor signaling pathway
    100010279 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    100010279 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    100010279 (MAPK12)
   04660 T cell receptor signaling pathway
    100010279 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    100010279 (MAPK12)
   04659 Th17 cell differentiation
    100010279 (MAPK12)
   04657 IL-17 signaling pathway
    100010279 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    100010279 (MAPK12)
   04670 Leukocyte transendothelial migration
    100010279 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100010279 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    100010279 (MAPK12)
   04917 Prolactin signaling pathway
    100010279 (MAPK12)
   04926 Relaxin signaling pathway
    100010279 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    100010279 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100010279 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    100010279 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    100010279 (MAPK12)
   04722 Neurotrophin signaling pathway
    100010279 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100010279 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100010279 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    100010279 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100010279 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    100010279 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100010279 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100010279 (MAPK12)
   05161 Hepatitis B
    100010279 (MAPK12)
   05171 Coronavirus disease
    100010279 (MAPK12)
   05163 Human cytomegalovirus infection
    100010279 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100010279 (MAPK12)
   05169 Epstein-Barr virus infection
    100010279 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100010279 (MAPK12)
   05135 Yersinia infection
    100010279 (MAPK12)
   05133 Pertussis
    100010279 (MAPK12)
   05152 Tuberculosis
    100010279 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100010279 (MAPK12)
   05140 Leishmaniasis
    100010279 (MAPK12)
   05142 Chagas disease
    100010279 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100010279 (MAPK12)
   05020 Prion disease
    100010279 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    100010279 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100010279 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    100010279 (MAPK12)
   05415 Diabetic cardiomyopathy
    100010279 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100010279 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    100010279 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100010279 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100010279 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mdo01001]
    100010279 (MAPK12)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100010279 (MAPK12)
Protein kinases [BR:mdo01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100010279 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH Kdo Kinase-like Haspin_kinase DUF3381 FTA2
Other DBs
NCBI-GeneID: 100010279
NCBI-ProteinID: XP_001362221
UniProt: A0A5F8H2N4
Position
8:complement(14931718..14949866)
AA seq 364 aa
MSSPPPPRKGFYRQEVTKTAWEVRELYRDLQPVGSGAYGAVCSAIDSRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDDTLDDFTDFYLVMPFMGTDLSKLM
KHEQLSDDRIQFLVYQILRGLKYIHAAGIVHRDLKPGNLAVNEDCELKILDFGLARQTDS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGSDHLDQLMEIMK
VTGTPPPEFVQRLQSQDAKNYMENLPELEKKDFASILKNATPLAVNLLEKMLVLDAEKRV
TAAEALTHPYFETVHESEEEPQAQLYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRLLDAK
ETSL
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgagttcccctccgcccccccggaagggcttttaccggcaggaggtcactaagacagct
tgggaggtgcgggaactctaccgcgacctgcagcccgtgggctctggggcttacggggcc
gtgtgctcggccattgacagcaggaccggcaccaaggtggccatcaagaaactgtaccgt
cccttccagtcggagctgttcgccaagcgcgcctaccgggagctgcggctactcaaacac
atgcgccatgagaatgtgattggcttactggatgtcttcaccccggatgacacgctggat
gacttcacagacttttacctggtcatgccattcatgggcacggatctcagcaagctgatg
aaacatgagcagctcagcgacgaccggatccagttcttggtttaccagattcttcggggg
ctcaagtacatccatgctgctggcatcgtccacagggatctcaagcctggtaacctggca
gtgaatgaggactgtgagctgaagattctggactttggcctggccagacagacagacagt
gagatgactggctacgtggtgaccagatggtaccgggcacctgaggtcatcctcaactgg
atgcgttacacccagacagtggatatctggtctgtgggctgcatcatggcagagatgatc
accgggaagatccttttcaaagggagtgaccacctggaccagctgatggagatcatgaag
gtgaccgggacacctccccctgagttcgtgcagcgccttcagagtcaggatgccaagaac
tacatggagaatctcccggagctggagaagaaggactttgcctccatcctgaagaacgcg
acccccctggctgtgaacctgctcgagaagatgttggtactggatgccgagaagcgagtg
acagccgcagaggcgctgactcacccatactttgagaccgtgcatgaatctgaggaggag
ccccaggcccagctctatgatgactcctttgatgacgttgaccggacattggaggagtgg
aaacgagtcacatacaaagaagtcctcagctttaagccccctcggcttctggatgcaaag
gaaacatctctgtga

  All links  
Gene (13)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (26)   

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