KEGG   Alexandromys fortis (reed vole): 126491593
Entry
126491593         CDS       T08493                                 
Name
(RefSeq) insulin receptor isoform X1
  KO
K04527  insulin receptor [EC:2.7.10.1]
Organism
mfot  Alexandromys fortis (reed vole)
Pathway
mfot04010  MAPK signaling pathway
mfot04014  Ras signaling pathway
mfot04015  Rap1 signaling pathway
mfot04022  cGMP-PKG signaling pathway
mfot04066  HIF-1 signaling pathway
mfot04068  FoxO signaling pathway
mfot04072  Phospholipase D signaling pathway
mfot04081  Hormone signaling
mfot04150  mTOR signaling pathway
mfot04151  PI3K-Akt signaling pathway
mfot04152  AMPK signaling pathway
mfot04211  Longevity regulating pathway
mfot04213  Longevity regulating pathway - multiple species
mfot04520  Adherens junction
mfot04910  Insulin signaling pathway
mfot04913  Ovarian steroidogenesis
mfot04923  Regulation of lipolysis in adipocytes
mfot04930  Type II diabetes mellitus
mfot04931  Insulin resistance
mfot04932  Non-alcoholic fatty liver disease
mfot04960  Aldosterone-regulated sodium reabsorption
mfot05010  Alzheimer disease
mfot05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mfot00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    126491593
   04014 Ras signaling pathway
    126491593
   04015 Rap1 signaling pathway
    126491593
   04066 HIF-1 signaling pathway
    126491593
   04068 FoxO signaling pathway
    126491593
   04072 Phospholipase D signaling pathway
    126491593
   04022 cGMP-PKG signaling pathway
    126491593
   04151 PI3K-Akt signaling pathway
    126491593
   04152 AMPK signaling pathway
    126491593
   04150 mTOR signaling pathway
    126491593
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    126491593
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    126491593
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    126491593
   04923 Regulation of lipolysis in adipocytes
    126491593
   04913 Ovarian steroidogenesis
    126491593
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    126491593
  09149 Aging
   04211 Longevity regulating pathway
    126491593
   04213 Longevity regulating pathway - multiple species
    126491593
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    126491593
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    126491593
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    126491593
   04932 Non-alcoholic fatty liver disease
    126491593
   04931 Insulin resistance
    126491593
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mfot01001]
    126491593
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:mfot04090]
    126491593
Enzymes [BR:mfot01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     126491593
Protein kinases [BR:mfot01001]
 Receptor tyrosine kinases (RTK)
  INSR family [OT]
   126491593
CD molecules [BR:mfot04090]
 Proteins
  126491593
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like DUF4476
Other DBs
NCBI-GeneID: 126491593
NCBI-ProteinID: XP_049983298
Position
Unknown
AA seq 1382 aa
MGSGKRRETLPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQI
LLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVI
FEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEEC
GDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECLGN
CSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPGCH
QYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGCTV
INGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETLEI
GNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEISGTKGRQERN
DIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNV
TEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWE
RQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRKPSAGSGAEDTRPSRKRRSLEEVGNVTATMPTLPDF
PNTSSTIAPTSQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV
SRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMT
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDN
CPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELEME
FEDMENVPLDRSSHCHREEAGGREGGSTLSIKRTYDEHIPYTHMNGGKKNGRVLTLPRSN
PS
NT seq 4149 nt   +upstreamnt  +downstreamnt
atgggctccgggaaacgacgtgagaccttgccgttgctggtggccgtggccgcgttgctg
gtgggcgcagccggccacctgtaccccggcgaggtgtgccctggcatggacatcaggaac
aacctgaccaggctgcatgagctggagaactgctcagtcatcgagggccatctgcagatc
ctcttgatgttcaaaaccagacccgaagatttccgagacctcagtttccccaaactcatc
atgatcacagactacctgcttcttttccgtgtctatggcctggagagtttgaaagacctc
ttccccaaccttacagtcatccgaggctcccgcctcttcttcaactatgccctggtcatc
tttgagatggtccacttgaaggagctggggctctacaacctcatgaacatcacccggggc
tctgtccgcattgagaagaataatgagctctgttacctggccaccattgactggtctcgg
atcttggattctgtggaggacaactacatcgtgctgaacaaagatgacaatgaggagtgt
ggggatgtctgtccaggcactgccaagggcaagaccaactgccctgccaccgtcatcaat
gggcagtttgtggaacggtgctggacacacagtcattgtcagaaagtttgtccgaccatc
tgtaagtcacatggctgcacagctgaaggcctgtgctgccacaaggagtgcctaggcaac
tgttcggaacccgatgaccccaccaagtgtgtggcctgtcgcaacttctacctggatggt
cgctgtgtggagacctgcccgcccccttactaccacttccaggattggcgctgtgtgaac
ttcagcttctgccaagaccttcactacaaatgcagaaactctaggaagcccggctgtcac
caatacgtcattcacaacaacaagtgcatcccggagtgtccttctggctatacaatgaat
tccagcaacttaatgtgcaccccgtgtctgggaccctgccctaaggtctgccaaatcctc
gacggcgagaagaccattgactctgtgacatctgcccaggagctccgaggctgcactgtg
atcaatggcagcctgatcatcaacattcgaggaggcaacaatctggcagctgagctggag
gctaaccttggcctcattgaagaaatctcagggttcctaaagatccggcgctcctatgct
ctagtatcgctttctttcttccggaagctacatctgattcgaggagagaccttggaaatc
gggaactactctttctatgccttggacaaccagaacctcaggcagctctgggactggagc
aagcacaacctcaccatcactcagggcaagctcttcttccactacaaccccaaactctgc
ttgtcagaaatccataagatggaagagatttctggaactaagggccgccaggagaggaac
gacattgccctgaagaccaatggggaccaggcatcctgtgaaaatgagttacttaaattt
tctttcattcggacatcttttgacaagatcttgctgaggtgggagccctactggccccct
gacttccgagacctcttgggattcatgcttttctacaaagaggccccttatcagaatgtg
acggagtttgatggtcaggatgcttgtggctccaacagctggactgtggtagatattgac
ccaccccagaggtccaacgaccccaagtctcaaaccccaagccaccctgggtggctaatg
cggggtctcaagccctggacccaatatgccatctttgtcaagaccttggttaccttctca
gatgaacgccggacctacggagccaaaagtgacatcatctatgtgcagacagatgccacc
aatccttctgtccccctggaccccatatcggtttctaattcctcatctcagattatctta
aagtggaagcccccctctgaccccaacggcaacatcacacactacttggtctactgggag
aggcaggcagaggacagcgagctgtttgagttggattattgtctcaaagggctgaagctc
ccctcacggacctggtccccaccttttgagtctgatgattctcagaagcacaatcagagc
gagtatgacgattcagccagcgaatgctgttcctgccccaagaccgactctcagatcctg
aaggagctggaagagtcttcgtttaggaagacctttgaggattacctgcataatgtggtt
tttgtccccagaaaaccctctgcaggcagtggtgccgaggacactaggccatctcgaaag
cgaagatcccttgaagaggtggggaatgtgacagccaccatgcctacacttccagatttt
cctaacacctcctccaccattgcacctacgagtcaggaggaacacaggccatttgagaaa
gtggtgaacaaggagtcacttgtcatctctggcctgagacacttcactggctatcgcatt
gagctgcaggcatgcaaccaagactccccagaagagaggtgcagtgtggctgcctacgtc
agtgcccggaccatgcctgaagctaaggcagatgacattgttggccctgtgacccacgaa
atctttgagaacaatgttgtacacttaatgtggcaagaaccaaaggaacccaatggtctg
attgtgctgtatgaagtgagctatcggcgatatggcgatgaggagctgcacctctgtgtc
tccaggaagcattttgccctggagcggggctgcaggcttagagggctctccccagggaac
tacagtgttcgagtccgggctacctccctggcaggcaatggctcctggacagaacccacc
tatttttacgtgactgattatttagatgtcccatcaaatattgccaaaattatcatcggg
cccctcatctttgtcttcctcttcagtgttgtgattggaagtatttatctattcctgaga
aagaggcagccagatgggccgatgggaccattgtatgcatcttcaaaccctgaatacctc
agtgccagtgatgtgtttccttcttctgtgtacgtgccggatgagtgggaggtgcctcga
gagaagatcacccttctacgagagctggggcagggatcctttggtatggtgtatgagggc
aatgccaaggatatcatcaagggtgaggcagagacccgtgttgcagtgaagactgtcaat
gagtcagccagtctccgagaacggatcgagttcctcaacgaggcatcggtcatgaaggga
ttcacctgccatcatgtggttcgcctccttggggtggtatccaaaggccagccaacactg
gtagtgatggaattgatggctcatggagacctgaagagtcacctccgttccctgcgcccg
gatgctgaaaataacccaggccgtcctccccctaccttgcaagagatgattcagatgaca
gcagaaattgctgatggcatggcatacttgaatgccaagaagtttgtgcaccgggacctg
gcagctcgaaactgcatggttgctcatgattttaccgtcaaaattggagactttgggatg
acgagagacatctatgagacagattactatcggaaagggggcaagggcttgctgcctgta
cggtggatgtcacctgagtccttgaaggacggagtctttactgcttcttctgatatgtgg
tcctttggggtggtcctttgggaaatcactagcctggctgagcaaccataccaaggcctg
tctaacgaacaggtgttgaaatttgtcatggatggaggctatctggatccacctgataat
tgtcctgagagactcactgacctgatgcgcatgtgctggcagttcaaccccaagatgagg
ccaaccttcctggaaattgtcaacctgctgaaggatgacctccaccccagctttccagag
gtttccttcttctacagcgaagagaacaaggctcccgagagtgaggagctggagatggag
ttcgaggacatggagaatgtccccttggatcggtcctctcactgtcacagggaagaagct
gggggccgggagggagggtccactctgagcatcaaacggacctatgatgaacacatccca
tacacccacatgaacgggggcaagaagaatgggcgtgtgctcaccctgcccaggtcaaac
ccttcctaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (9)   
   Pfam (9)   
All databases (17)   

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