KEGG   Alexandromys fortis (reed vole): 126494829
Entry
126494829         CDS       T08493                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mfot  Alexandromys fortis (reed vole)
Pathway
mfot00562  Inositol phosphate metabolism
mfot01100  Metabolic pathways
mfot04015  Rap1 signaling pathway
mfot04020  Calcium signaling pathway
mfot04022  cGMP-PKG signaling pathway
mfot04062  Chemokine signaling pathway
mfot04070  Phosphatidylinositol signaling system
mfot04071  Sphingolipid signaling pathway
mfot04072  Phospholipase D signaling pathway
mfot04081  Hormone signaling
mfot04082  Neuroactive ligand signaling
mfot04261  Adrenergic signaling in cardiomyocytes
mfot04270  Vascular smooth muscle contraction
mfot04310  Wnt signaling pathway
mfot04371  Apelin signaling pathway
mfot04540  Gap junction
mfot04611  Platelet activation
mfot04613  Neutrophil extracellular trap formation
mfot04621  NOD-like receptor signaling pathway
mfot04713  Circadian entrainment
mfot04720  Long-term potentiation
mfot04723  Retrograde endocannabinoid signaling
mfot04724  Glutamatergic synapse
mfot04725  Cholinergic synapse
mfot04726  Serotonergic synapse
mfot04728  Dopaminergic synapse
mfot04730  Long-term depression
mfot04742  Taste transduction
mfot04750  Inflammatory mediator regulation of TRP channels
mfot04911  Insulin secretion
mfot04912  GnRH signaling pathway
mfot04915  Estrogen signaling pathway
mfot04916  Melanogenesis
mfot04918  Thyroid hormone synthesis
mfot04919  Thyroid hormone signaling pathway
mfot04921  Oxytocin signaling pathway
mfot04922  Glucagon signaling pathway
mfot04924  Renin secretion
mfot04925  Aldosterone synthesis and secretion
mfot04926  Relaxin signaling pathway
mfot04927  Cortisol synthesis and secretion
mfot04928  Parathyroid hormone synthesis, secretion and action
mfot04929  GnRH secretion
mfot04933  AGE-RAGE signaling pathway in diabetic complications
mfot04934  Cushing syndrome
mfot04935  Growth hormone synthesis, secretion and action
mfot04961  Endocrine and other factor-regulated calcium reabsorption
mfot04970  Salivary secretion
mfot04971  Gastric acid secretion
mfot04972  Pancreatic secretion
mfot04973  Carbohydrate digestion and absorption
mfot05010  Alzheimer disease
mfot05016  Huntington disease
mfot05017  Spinocerebellar ataxia
mfot05022  Pathways of neurodegeneration - multiple diseases
mfot05142  Chagas disease
mfot05143  African trypanosomiasis
mfot05146  Amoebiasis
mfot05163  Human cytomegalovirus infection
mfot05200  Pathways in cancer
mfot05415  Diabetic cardiomyopathy
mfot05417  Lipid and atherosclerosis
Module
mfot_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mfot00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    126494829
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    126494829
   04310 Wnt signaling pathway
    126494829
   04371 Apelin signaling pathway
    126494829
   04020 Calcium signaling pathway
    126494829
   04070 Phosphatidylinositol signaling system
    126494829
   04072 Phospholipase D signaling pathway
    126494829
   04071 Sphingolipid signaling pathway
    126494829
   04022 cGMP-PKG signaling pathway
    126494829
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    126494829
   04081 Hormone signaling
    126494829
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    126494829
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    126494829
   04613 Neutrophil extracellular trap formation
    126494829
   04621 NOD-like receptor signaling pathway
    126494829
   04062 Chemokine signaling pathway
    126494829
  09152 Endocrine system
   04911 Insulin secretion
    126494829
   04922 Glucagon signaling pathway
    126494829
   04929 GnRH secretion
    126494829
   04912 GnRH signaling pathway
    126494829
   04915 Estrogen signaling pathway
    126494829
   04921 Oxytocin signaling pathway
    126494829
   04926 Relaxin signaling pathway
    126494829
   04935 Growth hormone synthesis, secretion and action
    126494829
   04918 Thyroid hormone synthesis
    126494829
   04919 Thyroid hormone signaling pathway
    126494829
   04928 Parathyroid hormone synthesis, secretion and action
    126494829
   04916 Melanogenesis
    126494829
   04924 Renin secretion
    126494829
   04925 Aldosterone synthesis and secretion
    126494829
   04927 Cortisol synthesis and secretion
    126494829
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    126494829
   04270 Vascular smooth muscle contraction
    126494829
  09154 Digestive system
   04970 Salivary secretion
    126494829
   04971 Gastric acid secretion
    126494829
   04972 Pancreatic secretion
    126494829
   04973 Carbohydrate digestion and absorption
    126494829
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    126494829
  09156 Nervous system
   04724 Glutamatergic synapse
    126494829
   04725 Cholinergic synapse
    126494829
   04728 Dopaminergic synapse
    126494829
   04726 Serotonergic synapse
    126494829
   04720 Long-term potentiation
    126494829
   04730 Long-term depression
    126494829
   04723 Retrograde endocannabinoid signaling
    126494829
  09157 Sensory system
   04742 Taste transduction
    126494829
   04750 Inflammatory mediator regulation of TRP channels
    126494829
  09159 Environmental adaptation
   04713 Circadian entrainment
    126494829
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    126494829
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    126494829
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    126494829
   05142 Chagas disease
    126494829
   05143 African trypanosomiasis
    126494829
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    126494829
   05016 Huntington disease
    126494829
   05017 Spinocerebellar ataxia
    126494829
   05022 Pathways of neurodegeneration - multiple diseases
    126494829
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126494829
   05415 Diabetic cardiomyopathy
    126494829
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    126494829
   04934 Cushing syndrome
    126494829
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mfot04131]
    126494829
Enzymes [BR:mfot01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     126494829
Membrane trafficking [BR:mfot04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    126494829
 Endocytosis
  Macropinocytosis
   Phospholipase C
    126494829
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 126494829
NCBI-ProteinID: XP_049988212
Position
Unknown
AA seq 1216 aa
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVSPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMITVVYGPDLVNISHLNLV
AFQEEVAKEWTSEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVEQMMDFINFKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYVSLRNER
NQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
EAEPGETSSEAPSEARTTPAENGVNHTTSLAPKPPSQAPHSQPAPGSVKAPAKTEDLVQS
VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTAELLKEHTTKYNEIQNDYL
RRRAALEKSAKKDSKKKSEPSSPDHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILEEKP
KLQMELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPPSLASDPGKVNHRSPSS
EEVEVENPGKEFDTPL
NT seq 3651 nt   +upstreamnt  +downstreamnt
atggctggggcacagcccggagtgcacgccttgcaactcaagccagtgtgcgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgactccactattgtttctcca
attattttgaggactgatcctcagggatttttcttttactggacagatcaaaacaaggag
acggagctgttagacctcagccttgtcaaggatgccaggtgtgggaaacatgccaaagct
cccaaggaccccaagttacgtgaactcctggatgttgggaacattgggcacctggagcaa
cgcatgataacggtggtgtatgggcctgacctggtgaacatctctcacttgaatctcgtg
gctttccaagaggaggtggccaaggaatggacaagtgaagttttcagcttggcaacaaac
ctactggctcagaacatgtccagagacgcatttctggagaaagcatatactaagctcaag
cttcaggtcactccagaagggcgcattcctctcaaaaacatctaccgattgttttcagca
gaccggaaacgagttgaaactgcactagaggcttgtagtcttccatcttcaaggaatgat
tccatacctcaagaggatttcactccagatgtatacagagttttcctgaacaacctttgt
ccccgacctgaaattgataacatcttttctgaatttggtgccaaaagcaaaccgtacctt
accgtcgagcagatgatggacttcatcaactttaaacagagagatccccggctcaatgaa
atactttacccacctctgaagcaagagcaggtccaagtgttgattgagaagtatgagccc
aacagcagcctcgccaaaaaagggcagatgtcagtggatggattcatgcgctacctgagc
ggagaagaaaatggagtcgtttcacctgagaaactggatttgaacgaagacatgtctcag
cccctgtctcactatttcatcaattcctcacacaacacctacctcacagctggccagttg
gctgggaactcctctgtagagatgtatcgccaggtgcttctgtctggatgtcgctgcgtg
gagctggactgctggaagggaaggaccgcagaggaagagcccgtcatcacccatggattc
accatgacaacagaaatatccttcaaggaagtcatagaagccatcgcagagtgtgcgttc
aagacgtcacctttccccatcctcctgtcctttgagaaccacgtggattccccaaagcag
caagccaagatggccgagtattgccgattaatctttggtgatgccctccttatggagcca
ctggaaaaatacccactggaatctggggtacctcttccgagccctatggatttaatgtat
aaaatcttggtgaaaaacaagaagaaatcgcacaaatcgtcggagggaagtggtaaaaag
aagctctctgagcaagcctccaacacgtacagcgactcctccagcgtctttgagccctcg
tctccaggagctggggaagcggatacggaaagcgacgatgacgacgacgatgatgactgt
aaaaagtcttccatggatgaggggactgccggcagcgaggccatggccacagaagagatg
tctaacctcgtgaactatattcaacctgtcaagtttgagtcctttgaaatttcaaaaaag
agaaataaaagctttgaaatgtcttccttcgtggaaaccaaaggacttgagcaacttaca
aagtctccagtggaatttgtagaatacaacaagatgcaacttagcaggatctatcccaaa
ggaacacgcgtggactcctccaactacatgccccagctcttctggaatgccggctgccag
atggtggcactcaacttccagaccgtggacctagctatgcagatcaacatgggcatgtat
gagtacaatgggaagagcggctacaggctaaagccagagttcatgaggaggccggacaag
cattttgatccatttactgaaggaatcgtagatgggatagtggccaacactctatccgtt
aagattatttcaggccagtttctctccgataagaaggttgggacttacgtggaggtggat
atgtttggtttgcctgtggacacaaggagaaaggcttttaaaaccaagacatcccaggga
aatgctgtgaatcctgtgtgggaggaagaacccattgtgtttaaaaaggtagttctgcct
tctctggcctgtttgaggatagcagcatatgaagaaggaggtaaatttattggccaccga
atcttgcctgtgcaggctattcggccaggctatcactatgtctccctgcggaatgagagg
aaccagcccctgatgctgccagctgtctttgtctacatagaagtcaaagactatgtgcca
gacacatatgcagatgtgatcgaagctctgtcaaacccaatccggtatgtcaacctgatg
gagcagagagcgaagcagctggccgcattgacgctggaggatgaagaggaagtaaagaaa
gaggctgagcctggggaaacgtcatcagaggcgccgagtgaagccaggacaacgcccgca
gaaaatggggtgaatcacacaacatccctggcccccaaaccaccttcccaggctccacac
agccagccagctccaggttctgttaaggcgcccgccaaaacagaagacctggtccagagt
gtcttaacagaagtagaggcgcagaccatcgaagagctcaagcaacagaaatcgttcgtg
aaacttcaaaagaagcactacaaagaaatgaaagacctggtcaagagacaccacaagaaa
accgccgagctcctcaaggagcacaccaccaagtacaatgagattcagaatgactacctg
aggaggagagcagccttggaaaagtccgccaagaaggacagcaagaaaaaatctgaaccc
agcagccctgaccatggctcgtcggccattgagcaagacctcgctgccctggatgcagaa
atgacccagaagttaatagacttgaaggacaagcagcaacagcagctgctcaacctccgg
caagaacagtattacagcgagaagtaccagaagcgagagcatattaagctgcttattcag
aagttgacagatgttgccgaggagtgtcagaacaaccagctcaagaagctcaaggagatc
tgcgagaaagagaagaaggaattaaagaagaaaatggataaaaagaggcaggagaagata
acagaagccaagtccaaagacaaaagccagatggaagaggagaagacagagatgatccgg
tcgtacatccaggaggtggtgcagtacatcaagaggttagaggaagcacaaagtaaaaga
caagaaaagcttgtggagaaacacaaggagatccgccagcagatcctagaggagaagccc
aagctgcagatggagctggagcaagaataccaagacaagttcaaaagactgcccctggag
attctggagttcgtacaggaggccatgaaagggaagatcagtgaagacagcaatcacggt
tccgcccctccctctctggcctcagaccctggaaaggtgaaccacaggtctccctccagt
gaggaagtggaggttgagaatccgggaaaagagtttgatactcctctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (6)   
   Pfam (6)   
All databases (14)   

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