KEGG   Marmota marmota marmota (Alpine marmot): 107141811
Entry
107141811         CDS       T09644                                 
Symbol
Pik3r3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma01521  EGFR tyrosine kinase inhibitor resistance
mmma01522  Endocrine resistance
mmma01524  Platinum drug resistance
mmma04012  ErbB signaling pathway
mmma04014  Ras signaling pathway
mmma04015  Rap1 signaling pathway
mmma04024  cAMP signaling pathway
mmma04062  Chemokine signaling pathway
mmma04066  HIF-1 signaling pathway
mmma04068  FoxO signaling pathway
mmma04070  Phosphatidylinositol signaling system
mmma04071  Sphingolipid signaling pathway
mmma04072  Phospholipase D signaling pathway
mmma04081  Hormone signaling
mmma04140  Autophagy - animal
mmma04145  Phagocytosis
mmma04150  mTOR signaling pathway
mmma04151  PI3K-Akt signaling pathway
mmma04152  AMPK signaling pathway
mmma04210  Apoptosis
mmma04211  Longevity regulating pathway
mmma04213  Longevity regulating pathway - multiple species
mmma04218  Cellular senescence
mmma04360  Axon guidance
mmma04370  VEGF signaling pathway
mmma04380  Osteoclast differentiation
mmma04510  Focal adhesion
mmma04517  IgSF CAM signaling
mmma04518  Integrin signaling
mmma04550  Signaling pathways regulating pluripotency of stem cells
mmma04611  Platelet activation
mmma04613  Neutrophil extracellular trap formation
mmma04620  Toll-like receptor signaling pathway
mmma04625  C-type lectin receptor signaling pathway
mmma04630  JAK-STAT signaling pathway
mmma04650  Natural killer cell mediated cytotoxicity
mmma04660  T cell receptor signaling pathway
mmma04662  B cell receptor signaling pathway
mmma04664  Fc epsilon RI signaling pathway
mmma04666  Fc gamma R-mediated phagosome formation
mmma04668  TNF signaling pathway
mmma04670  Leukocyte transendothelial migration
mmma04722  Neurotrophin signaling pathway
mmma04725  Cholinergic synapse
mmma04750  Inflammatory mediator regulation of TRP channels
mmma04810  Regulation of actin cytoskeleton
mmma04910  Insulin signaling pathway
mmma04914  Progesterone-mediated oocyte maturation
mmma04915  Estrogen signaling pathway
mmma04917  Prolactin signaling pathway
mmma04919  Thyroid hormone signaling pathway
mmma04923  Regulation of lipolysis in adipocytes
mmma04926  Relaxin signaling pathway
mmma04929  GnRH secretion
mmma04930  Type II diabetes mellitus
mmma04931  Insulin resistance
mmma04932  Non-alcoholic fatty liver disease
mmma04933  AGE-RAGE signaling pathway in diabetic complications
mmma04935  Growth hormone synthesis, secretion and action
mmma04960  Aldosterone-regulated sodium reabsorption
mmma04973  Carbohydrate digestion and absorption
mmma05010  Alzheimer disease
mmma05017  Spinocerebellar ataxia
mmma05020  Prion disease
mmma05100  Bacterial invasion of epithelial cells
mmma05135  Yersinia infection
mmma05142  Chagas disease
mmma05146  Amoebiasis
mmma05160  Hepatitis C
mmma05161  Hepatitis B
mmma05162  Measles
mmma05163  Human cytomegalovirus infection
mmma05164  Influenza A
mmma05165  Human papillomavirus infection
mmma05166  Human T-cell leukemia virus 1 infection
mmma05167  Kaposi sarcoma-associated herpesvirus infection
mmma05168  Herpes simplex virus 1 infection
mmma05169  Epstein-Barr virus infection
mmma05170  Human immunodeficiency virus 1 infection
mmma05171  Coronavirus disease
mmma05200  Pathways in cancer
mmma05203  Viral carcinogenesis
mmma05205  Proteoglycans in cancer
mmma05206  MicroRNAs in cancer
mmma05207  Chemical carcinogenesis - receptor activation
mmma05208  Chemical carcinogenesis - reactive oxygen species
mmma05210  Colorectal cancer
mmma05211  Renal cell carcinoma
mmma05212  Pancreatic cancer
mmma05213  Endometrial cancer
mmma05214  Glioma
mmma05215  Prostate cancer
mmma05218  Melanoma
mmma05220  Chronic myeloid leukemia
mmma05221  Acute myeloid leukemia
mmma05222  Small cell lung cancer
mmma05223  Non-small cell lung cancer
mmma05224  Breast cancer
mmma05225  Hepatocellular carcinoma
mmma05226  Gastric cancer
mmma05230  Central carbon metabolism in cancer
mmma05231  Choline metabolism in cancer
mmma05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mmma05415  Diabetic cardiomyopathy
mmma05417  Lipid and atherosclerosis
mmma05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    107141811 (Pik3r3)
   04014 Ras signaling pathway
    107141811 (Pik3r3)
   04015 Rap1 signaling pathway
    107141811 (Pik3r3)
   04370 VEGF signaling pathway
    107141811 (Pik3r3)
   04630 JAK-STAT signaling pathway
    107141811 (Pik3r3)
   04668 TNF signaling pathway
    107141811 (Pik3r3)
   04066 HIF-1 signaling pathway
    107141811 (Pik3r3)
   04068 FoxO signaling pathway
    107141811 (Pik3r3)
   04070 Phosphatidylinositol signaling system
    107141811 (Pik3r3)
   04072 Phospholipase D signaling pathway
    107141811 (Pik3r3)
   04071 Sphingolipid signaling pathway
    107141811 (Pik3r3)
   04024 cAMP signaling pathway
    107141811 (Pik3r3)
   04151 PI3K-Akt signaling pathway
    107141811 (Pik3r3)
   04152 AMPK signaling pathway
    107141811 (Pik3r3)
   04150 mTOR signaling pathway
    107141811 (Pik3r3)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    107141811 (Pik3r3)
   04517 IgSF CAM signaling
    107141811 (Pik3r3)
   04518 Integrin signaling
    107141811 (Pik3r3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    107141811 (Pik3r3)
   04140 Autophagy - animal
    107141811 (Pik3r3)
  09143 Cell growth and death
   04210 Apoptosis
    107141811 (Pik3r3)
   04218 Cellular senescence
    107141811 (Pik3r3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107141811 (Pik3r3)
   04550 Signaling pathways regulating pluripotency of stem cells
    107141811 (Pik3r3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107141811 (Pik3r3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107141811 (Pik3r3)
   04613 Neutrophil extracellular trap formation
    107141811 (Pik3r3)
   04620 Toll-like receptor signaling pathway
    107141811 (Pik3r3)
   04625 C-type lectin receptor signaling pathway
    107141811 (Pik3r3)
   04650 Natural killer cell mediated cytotoxicity
    107141811 (Pik3r3)
   04660 T cell receptor signaling pathway
    107141811 (Pik3r3)
   04662 B cell receptor signaling pathway
    107141811 (Pik3r3)
   04664 Fc epsilon RI signaling pathway
    107141811 (Pik3r3)
   04666 Fc gamma R-mediated phagosome formation
    107141811 (Pik3r3)
   04670 Leukocyte transendothelial migration
    107141811 (Pik3r3)
   04062 Chemokine signaling pathway
    107141811 (Pik3r3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    107141811 (Pik3r3)
   04923 Regulation of lipolysis in adipocytes
    107141811 (Pik3r3)
   04929 GnRH secretion
    107141811 (Pik3r3)
   04915 Estrogen signaling pathway
    107141811 (Pik3r3)
   04914 Progesterone-mediated oocyte maturation
    107141811 (Pik3r3)
   04917 Prolactin signaling pathway
    107141811 (Pik3r3)
   04926 Relaxin signaling pathway
    107141811 (Pik3r3)
   04935 Growth hormone synthesis, secretion and action
    107141811 (Pik3r3)
   04919 Thyroid hormone signaling pathway
    107141811 (Pik3r3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    107141811 (Pik3r3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    107141811 (Pik3r3)
  09156 Nervous system
   04725 Cholinergic synapse
    107141811 (Pik3r3)
   04722 Neurotrophin signaling pathway
    107141811 (Pik3r3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    107141811 (Pik3r3)
  09158 Development and regeneration
   04360 Axon guidance
    107141811 (Pik3r3)
   04380 Osteoclast differentiation
    107141811 (Pik3r3)
  09149 Aging
   04211 Longevity regulating pathway
    107141811 (Pik3r3)
   04213 Longevity regulating pathway - multiple species
    107141811 (Pik3r3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107141811 (Pik3r3)
   05206 MicroRNAs in cancer
    107141811 (Pik3r3)
   05205 Proteoglycans in cancer
    107141811 (Pik3r3)
   05207 Chemical carcinogenesis - receptor activation
    107141811 (Pik3r3)
   05208 Chemical carcinogenesis - reactive oxygen species
    107141811 (Pik3r3)
   05203 Viral carcinogenesis
    107141811 (Pik3r3)
   05230 Central carbon metabolism in cancer
    107141811 (Pik3r3)
   05231 Choline metabolism in cancer
    107141811 (Pik3r3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    107141811 (Pik3r3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    107141811 (Pik3r3)
   05212 Pancreatic cancer
    107141811 (Pik3r3)
   05225 Hepatocellular carcinoma
    107141811 (Pik3r3)
   05226 Gastric cancer
    107141811 (Pik3r3)
   05214 Glioma
    107141811 (Pik3r3)
   05221 Acute myeloid leukemia
    107141811 (Pik3r3)
   05220 Chronic myeloid leukemia
    107141811 (Pik3r3)
   05218 Melanoma
    107141811 (Pik3r3)
   05211 Renal cell carcinoma
    107141811 (Pik3r3)
   05215 Prostate cancer
    107141811 (Pik3r3)
   05213 Endometrial cancer
    107141811 (Pik3r3)
   05224 Breast cancer
    107141811 (Pik3r3)
   05222 Small cell lung cancer
    107141811 (Pik3r3)
   05223 Non-small cell lung cancer
    107141811 (Pik3r3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107141811 (Pik3r3)
   05170 Human immunodeficiency virus 1 infection
    107141811 (Pik3r3)
   05161 Hepatitis B
    107141811 (Pik3r3)
   05160 Hepatitis C
    107141811 (Pik3r3)
   05171 Coronavirus disease
    107141811 (Pik3r3)
   05164 Influenza A
    107141811 (Pik3r3)
   05162 Measles
    107141811 (Pik3r3)
   05168 Herpes simplex virus 1 infection
    107141811 (Pik3r3)
   05163 Human cytomegalovirus infection
    107141811 (Pik3r3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    107141811 (Pik3r3)
   05169 Epstein-Barr virus infection
    107141811 (Pik3r3)
   05165 Human papillomavirus infection
    107141811 (Pik3r3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    107141811 (Pik3r3)
   05100 Bacterial invasion of epithelial cells
    107141811 (Pik3r3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    107141811 (Pik3r3)
   05142 Chagas disease
    107141811 (Pik3r3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107141811 (Pik3r3)
   05017 Spinocerebellar ataxia
    107141811 (Pik3r3)
   05020 Prion disease
    107141811 (Pik3r3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    107141811 (Pik3r3)
   05418 Fluid shear stress and atherosclerosis
    107141811 (Pik3r3)
   05415 Diabetic cardiomyopathy
    107141811 (Pik3r3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107141811 (Pik3r3)
   04932 Non-alcoholic fatty liver disease
    107141811 (Pik3r3)
   04931 Insulin resistance
    107141811 (Pik3r3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    107141811 (Pik3r3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    107141811 (Pik3r3)
   01524 Platinum drug resistance
    107141811 (Pik3r3)
   01522 Endocrine resistance
    107141811 (Pik3r3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmma04131]
    107141811 (Pik3r3)
Membrane trafficking [BR:mmma04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    107141811 (Pik3r3)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 SH2_1 DicA_C ODF2_C Exonuc_VII_L
Other DBs
NCBI-GeneID: 107141811
NCBI-ProteinID: XP_015340540
Ensembl: ENSMMMG00000018977
UniProt: A0A8C5ZXE6
Position
Unknown
AA seq 461 aa
MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVTNGMKDSSISL
QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSKYQQDQLVKEDNIDAVGKK
LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEKDLKKQALDNREIDKKMNSIKP
DLIQLRKIRDQHLVWLNHKGVRQKRLNAWLGIKNEDADETYFINEEDENLPHYDEKTWFV
EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
LYSSLKELVLHYQQTSLIQHNDSLNVRLAYPVHAQMPSLCR
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgtacaatacggtgtggagtatggaccgcgatgacgcagactggagggaggtgatgatg
ccctattcgacagaactgatattttatattgaaatggatcctccagctcttccaccaaag
ccacctaagccaatgacttcagcagttacaaatggaatgaaggacagttccatttctctt
caggatgcagaatggtactggggagatatttccagggaggaggtaaatgacaaattacgg
gatatgccagatggtaccttcttggtccgagatgcctcaacaaaaatgcagggagattat
actttgactttgaggaagggaggcaataataagttaataaagatctatcatcgggatggt
aaatatggcttttctgatcctctgacatttaattctgtggtggagctcattaaccactat
catcatgaatctcttgctcagtacaatcccaaactcgatgtgaagcttatgtacccagtt
tccaaataccaacaggatcagttggtaaaagaagataacattgatgcagtaggtaaaaaa
ctgcaagagtaccactctcagtatcaggaaaagagtaaagagtatgataggctatatgaa
gaatataccagaacatcccaggaaatacagatgaagaggactgcaattgaagcttttaat
gaaactattaaaatatttgaagagcaatgtcacacacaagaacaacacagcaaagaatat
attgagcgatttcgcagagagggaaatgaaaaggagattgaacgaattatgatgaattat
gataaattgaaatcacgtcttggtgagattcatgacagcaaaatgcgtctagagaaggat
ttgaagaaacaagctttggacaaccgggaaatagataaaaaaatgaatagtatcaaacct
gacctgatacagctgcgcaagatccgagatcagcatcttgtatggctcaatcacaaagga
gtgagacagaagcgcctgaatgcctggctgggaatcaagaatgaggatgctgatgagacc
tattttatcaatgaggaagatgaaaacttgccacattatgatgagaaaacctggtttgtt
gaagatatcaatcgtgtacaagcagaggacttgctttatgggaaacctgatggtgcattc
ttaattcgtgaaagtagcaagaaaggatgctatgcctgctctgtggttgccgatggggaa
gtgaaacactgtgtgatctacagcactgctcggggatatggctttgcagagccctacaac
ctgtacagctcactgaaggagctggtgctccattaccagcagacatccctgattcagcac
aatgactccctcaacgttaggcttgcctatcctgttcatgcacagatgccttcactctgc
agataa

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (14)   

Download RDF
DBGET integrated database retrieval system