KEGG   Mus musculus (mouse): 20416
Entry
20416             CDS       T01002                                 

Gene name
Shc1, Sh, Shc, ShcA, p6, p66, p66s, p66shc
Definition
(RefSeq) src homology 2 domain-containing transforming protein C1
  KO
K06279  SHC-transforming protein 1
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu01522  Endocrine resistance
mmu04012  ErbB signaling pathway
mmu04014  Ras signaling pathway
mmu04062  Chemokine signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04510  Focal adhesion
mmu04650  Natural killer cell mediated cytotoxicity
mmu04722  Neurotrophin signaling pathway
mmu04910  Insulin signaling pathway
mmu04915  Estrogen signaling pathway
mmu04917  Prolactin signaling pathway
mmu04926  Relaxin signaling pathway
mmu04935  Growth hormone synthesis, secretion and action
mmu05034  Alcoholism
mmu05100  Bacterial invasion of epithelial cells
mmu05206  MicroRNAs in cancer
mmu05214  Glioma
mmu05220  Chronic myeloid leukemia
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    20416 (Shc1)
   04014 Ras signaling pathway
    20416 (Shc1)
   04072 Phospholipase D signaling pathway
    20416 (Shc1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    20416 (Shc1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    20416 (Shc1)
   04062 Chemokine signaling pathway
    20416 (Shc1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    20416 (Shc1)
   04915 Estrogen signaling pathway
    20416 (Shc1)
   04917 Prolactin signaling pathway
    20416 (Shc1)
   04926 Relaxin signaling pathway
    20416 (Shc1)
   04935 Growth hormone synthesis, secretion and action
    20416 (Shc1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    20416 (Shc1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    20416 (Shc1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    20416 (Shc1)
   05226 Gastric cancer
    20416 (Shc1)
   05214 Glioma
    20416 (Shc1)
   05220 Chronic myeloid leukemia
    20416 (Shc1)
   05224 Breast cancer
    20416 (Shc1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    20416 (Shc1)
  09165 Substance dependence
   05034 Alcoholism
    20416 (Shc1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    20416 (Shc1)
   01522 Endocrine resistance
    20416 (Shc1)
SSDB
Motif
Pfam: PID SH2 Delta_lysin
Other DBs
NCBI-GeneID: 20416
NCBI-ProteinID: NP_001106802
MGI: 98296
Ensembl: ENSMUSG00000042626
Vega: OTTMUSG00000022071
UniProt: P98083
Position
3 F1; 3 39.11 cM
AA seq 579 aa
MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS
FFPRMSNLKLANPAGGRLGPKGEPGKAAEDGEGSAGAALRDSGLLPLLQDMNKLSGGGGR
RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD
FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS
LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV
ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL
GGVVDMRLREGAARPTLPSAQMSSHLGATLPIGQHAAGDHEVRKQMLPPPPCPGRELFDD
PSYVNIQNLDKARQAGGGAGPPNPSLNGSAPRDLFDMKPFEDALRVPPPPQSMSMAEQLQ
GEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRT
KDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVDRKV
NT seq 1740 nt   +upstreamnt  +downstreamnt
atggatcttctaccccccaagccgaagtacaacccacttcggaatgagtctctgtcatcg
ctggaggagggggcttcggggtctacccctccggaggagctaccttccccatcagcttca
tccctgggacccattctgcctcctctgccgggggacgatagtccgactaccctgtgttcc
ttctttccccggatgagcaacctgaagctggccaatcctgctggggggcgcctggggcct
aaaggggagccaggaaaggctgctgaagatggggaagggagtgcaggggcagcccttcgg
gactcaggcctcttgcccctcctccaggacatgaacaagctgagtggaggcggcgggcgc
aggactcgggtagaagggggccagctggggggcgaggagtggaccagacacgggagcttt
gtcaataagcccacacgaggctggctgcatcccaacgacaaagtcatgggacctggggtt
tcctacttggttcggtacatgggctgtgtggaggtcttacagtcaatgcgagcccttgac
ttcaatacccggactcaggtcaccagggaggccatcagtttggtgtgtgaagctgtgcct
ggtgccaaaggggcgacaaggaggagaaagccttgtagccgcccactcagctccatcctg
gggaggagtaacctgaagtttgctggaatgccaatcactctcactgtgtctaccagcagc
cttaacctcatggcagccgactgcaaacagatcattgccaaccatcacatgcaatctatc
tctttcgcgtccggtggggatccggacacagctgagtatgttgcctatgttgccaaagac
cctgtgaatcagagagcctgccatatcctggagtgtcctgaagggcttgctcaggatgtc
atcagcaccatcgggcaggcctttgagttgcgcttcaaacagtatctcaggaatccaccg
aagctggtcaccccccatgacaggatggctggctttgatggctcagcttgggatgaggag
gaagaagagccccctgaccatcagtactacaatgactttccagggaaggaaccccctctt
ggtggggtggtagatatgaggcttcgggaaggggctgctcgacccactctgcctagtgcc
cagatgtccagccacttgggagctacactgcctatagggcagcatgctgcaggagaccat
gaagtccgtaaacagatgttgcctccgccgccttgcccaggcagagaactcttcgatgac
ccctcctatgtcaacatccagaatctagacaaggcccggcaggctgggggtggggctggg
cccccaaatccttctcttaatggcagtgcaccccgagacctttttgacatgaagcccttt
gaagatgcacttcgggtgccacccccaccgcagtccatgtccatggctgagcagctgcaa
ggggagccctggttccacgggaagctgagccggagggaggccgaggcgctgctgcagctc
aatggtgacttcttggtgcgagagagcacgaccacgcctggccagtatgtgctcactggc
ctgcagagtgggcagcccaagcacttgctgctggtggaccctgaaggtgtggttcggaca
aaggatcaccgctttgagagtgtcagtcacctgatcagctaccacatggacaatcacttg
cccatcatctctgcgggcagcgaactgtgcctacagcaacccgtggatcggaaagtgtga

KEGG   Mus musculus (mouse): 20418
Entry
20418             CDS       T01002                                 

Gene name
Shc3, N-S, N-Shc, Rai, Shc, ShcC
Definition
(RefSeq) src homology 2 domain-containing transforming protein C3
  KO
K17448  SHC-transforming protein 3
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu01522  Endocrine resistance
mmu04012  ErbB signaling pathway
mmu04014  Ras signaling pathway
mmu04062  Chemokine signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04510  Focal adhesion
mmu04650  Natural killer cell mediated cytotoxicity
mmu04722  Neurotrophin signaling pathway
mmu04910  Insulin signaling pathway
mmu04915  Estrogen signaling pathway
mmu04917  Prolactin signaling pathway
mmu04926  Relaxin signaling pathway
mmu04935  Growth hormone synthesis, secretion and action
mmu05034  Alcoholism
mmu05100  Bacterial invasion of epithelial cells
mmu05214  Glioma
mmu05220  Chronic myeloid leukemia
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    20418 (Shc3)
   04014 Ras signaling pathway
    20418 (Shc3)
   04072 Phospholipase D signaling pathway
    20418 (Shc3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    20418 (Shc3)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    20418 (Shc3)
   04062 Chemokine signaling pathway
    20418 (Shc3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    20418 (Shc3)
   04915 Estrogen signaling pathway
    20418 (Shc3)
   04917 Prolactin signaling pathway
    20418 (Shc3)
   04926 Relaxin signaling pathway
    20418 (Shc3)
   04935 Growth hormone synthesis, secretion and action
    20418 (Shc3)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    20418 (Shc3)
 09160 Human Diseases
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    20418 (Shc3)
   05226 Gastric cancer
    20418 (Shc3)
   05214 Glioma
    20418 (Shc3)
   05220 Chronic myeloid leukemia
    20418 (Shc3)
   05224 Breast cancer
    20418 (Shc3)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    20418 (Shc3)
  09165 Substance dependence
   05034 Alcoholism
    20418 (Shc3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    20418 (Shc3)
   01522 Endocrine resistance
    20418 (Shc3)
SSDB
Motif
Pfam: PID SH2
Other DBs
NCBI-GeneID: 20418
NCBI-ProteinID: NP_033193
MGI: 106179
Ensembl: ENSMUSG00000021448
UniProt: Q61120
Position
13 A5; 13 26.12 cM
AA seq 594 aa
MLPRTKYNRFRNDSVTSVDDLLHSLSVSGSGGKVSAEPAASPYLVSGEALRKAPDDGPGS
LGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGGSATPGSRAPAAS
MSATRKSRAGDEPLPRPPRGAPHTSDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQV
TREAISRVCEAVPGAKGALKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD
SKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQA
FELRFKQYLQCPSKVPALQDRMQSLDEPWTEEEGDGPDHPYYNSVPTKMPPPGGFLDARL
KGRPHAPEAAQFAGKEQTYYQGRHLGDTFGEDWQRAPTRQGSLDIYSTAEGKTHMVPVGE
TPTYVNTQPVPPQVWPAATSSTESSPRKDLFDMKPFEDALRNQPLGPMLSKAASVECISP
VTPRAPDARMLEELNAEPWYQGEMSRKEAEALLREDGDFLVRKSTTNPGSFVLTGMHNGQ
AKHLLLVDPEGTIRTKDRVFDSISHLINYHLESSLPIVSAGSELCLQQPVERKP
NT seq 1785 nt   +upstreamnt  +downstreamnt
atgcttccacgcaccaagtacaaccgcttcaggaatgactcggtgacatcggtcgatgac
cttctccacagcctgtcggtgagcggcagcggcggcaaggtctcggcggagcccgcggcg
agcccctacctggtgtcgggcgaggcgctgcgcaaggcgccggacgatgggcccggcagc
ctgggccacctgctccacaaggtgtcccacttgaaactctccagctccggcctgcgtggc
ctgtcgtcggccgcccgggagcgggcaggagcgcggctctcgggcagctgcagcgcgccc
agcctggcggccccggacggcggcagcgcgacccccgggtcccgcgccccggccgccagc
atgagtgccaccaggaagagccgggccggcgacgagccactgcccaggccccctcggggc
gcgccgcacaccagcgatcaggtgctggggccgggagtcacctatgtggtcaagtacttg
ggctgcatcgaagttctgcgctcaatgaggtctcttgacttcagtacaagaactcaggtt
accagggaagccatcagccgtgtctgcgaagctgtgccaggtgccaaaggagccctcaag
aagagaaagccgccgagtaagatgctgtccagcatcctggggaagagcaacctccagttc
gcagggatgagcatctccctgaccatctccaccgccagcctgaatctgcgcactcctgac
tccaaacagatcatagcgaaccatcatatgcggtctatctcttttgcctcagggggagac
ccggacacaacggactatgttgcctatgtcgctaaggaccctgtcaatcgcagagcttgc
cacattctggaatgctgtgacgggctagcccaagatgtcattggctccatcggacaagcc
tttgaactccggttcaaacagtatttgcagtgcccttccaaggttcctgccctccaggac
cgaatgcagagtctggatgagccatggactgaagaagagggagatggccctgatcaccca
tactacaacagcgttcccaccaagatgcctcccccaggggggtttctggatgctcgattg
aaaggcagaccccacgctcctgaggcagcccagtttgcaggaaaagagcaaacttattac
cagggaagacacttaggagatacatttggtgaagactggcagcgagcacccaccaggcaa
ggctccttggacatctatagcacagcagaagggaaaactcacatggttcctgtaggagaa
acaccaacctatgtcaacacccagccagtcccaccacaggtgtggccagcagcaaccagc
agcactgagagcagcccacggaaggacctctttgacatgaagccctttgaagatgccctg
agaaaccagcccctgggccccatgttgagcaaagccgcgtctgtggagtgcatcagcccg
gtcacacccagagccccggatgccaggatgctggaggagcttaacgctgagccctggtac
caaggagagatgagcaggaaggaggcagaggccctgctacgggaagatggagacttccta
gtgaggaagagtaccaccaaccccggctcctttgtcctcacaggcatgcacaatgggcag
gccaagcacctgctgctggtggacccggaaggcacgatccggacgaaggacagggtcttt
gacagcatcagccacctcatcaattaccacctcgagagcagcctgcccattgtctctgcc
gggagtgagctttgtctccagcaaccagtggagaggaaaccctga

KEGG   Mus musculus (mouse): 216148
Entry
216148            CDS       T01002                                 

Gene name
Shc2, 6720466E06, SCK, Shc, ShcB, Sli
Definition
(RefSeq) SHC (Src homology 2 domain containing) transforming protein 2
  KO
K17447  SHC-transforming protein 2
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu01522  Endocrine resistance
mmu04012  ErbB signaling pathway
mmu04014  Ras signaling pathway
mmu04062  Chemokine signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04370  VEGF signaling pathway
mmu04510  Focal adhesion
mmu04650  Natural killer cell mediated cytotoxicity
mmu04722  Neurotrophin signaling pathway
mmu04910  Insulin signaling pathway
mmu04915  Estrogen signaling pathway
mmu04917  Prolactin signaling pathway
mmu04926  Relaxin signaling pathway
mmu04935  Growth hormone synthesis, secretion and action
mmu05034  Alcoholism
mmu05100  Bacterial invasion of epithelial cells
mmu05214  Glioma
mmu05220  Chronic myeloid leukemia
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    216148 (Shc2)
   04014 Ras signaling pathway
    216148 (Shc2)
   04370 VEGF signaling pathway
    216148 (Shc2)
   04072 Phospholipase D signaling pathway
    216148 (Shc2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    216148 (Shc2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    216148 (Shc2)
   04062 Chemokine signaling pathway
    216148 (Shc2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    216148 (Shc2)
   04915 Estrogen signaling pathway
    216148 (Shc2)
   04917 Prolactin signaling pathway
    216148 (Shc2)
   04926 Relaxin signaling pathway
    216148 (Shc2)
   04935 Growth hormone synthesis, secretion and action
    216148 (Shc2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    216148 (Shc2)
 09160 Human Diseases
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    216148 (Shc2)
   05226 Gastric cancer
    216148 (Shc2)
   05214 Glioma
    216148 (Shc2)
   05220 Chronic myeloid leukemia
    216148 (Shc2)
   05224 Breast cancer
    216148 (Shc2)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    216148 (Shc2)
  09165 Substance dependence
   05034 Alcoholism
    216148 (Shc2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    216148 (Shc2)
   01522 Endocrine resistance
    216148 (Shc2)
SSDB
Motif
Pfam: PID SH2
Other DBs
NCBI-GeneID: 216148
NCBI-ProteinID: NP_001019710
MGI: 106180
Ensembl: ENSMUSG00000020312
UniProt: Q8BMC3
Position
10 C1; 10 39.72 cM
AA seq 573 aa
MTQGPGGRAAPEPEAPTTFCALLPRMPQWKFAAPGSFLGRGPAATRVAGVAEAQPEPGVP
ALAAVLGACEPRCAAPCPLPALGRCRGSGTRGARVTPDVADEWVRKGGFIHKPAHGWLHP
DARVLGPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRGSWKKKAP
NKALASILGKSNLRFAGMSISVNISVDGLNLSVPATRQIIANHHMQSISFASGGDTDMTD
YVAYVAKDPINQRACHILECCEGLAQSVISTVGQAFELRFKQYLHSPPKAVVPPERLTGL
EELAWGDDDAAADHNYYNSIPGKEPPLGGLVDSRLAVTQPCALATLGGLGQGMTPVWRDA
RGLPWDMGPSGAAPPGDGYVQADARGPHDYEEHLYVNTQGLDAVELEDTAEAPLQFEDSP
KKDLFDMRPFEDALKLHACSVAAGITAASPPLEDQWPSPPTRRAPIAPTEEQLRQEPWYH
GRMSRRAAEKLLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFE
SISHLIDYHLKNGLPIVAAESELHLRGVVSREP
NT seq 1722 nt   +upstreamnt  +downstreamnt
atgacgcagggtccgggtggccgcgcggcccccgagcccgaggcgcccaccaccttctgc
gcactgctgccgcggatgccgcagtggaagttcgcagcgccgggtagcttcctgggccgc
ggtcccgcggcgacgcgcgtggcgggggtggcagaggcgcagccggagcccggggtcccc
gcgctggccgctgtgttgggcgcttgcgaaccgcgctgcgccgcgccctgtccgctgccc
gcgctcggccgctgccggggctcggggacgcggggcgcgcgggtgactccggatgtcgct
gacgagtgggtgcgcaagggcggcttcattcacaagccggcgcacggctggttgcatccc
gatgccagggtcctggggcccggggtctcttacatcgttcggtacatgggctgcattgag
gtgcttcgatccatgcgctccctggatttcaacacccgaacacaggtgacgagggaagcc
atcaatcggctccatgaggctgtgcccggtgtccggggctcctggaagaagaaggccccc
aacaaggctctggcctccatcttggggaaaagcaacctgcgcttcgccggcatgagcatc
tcagtcaacatctccgtggacggccttaacttgtctgttcccgccacccgccagatcatc
gccaaccatcatatgcagtctatttccttcgcctcgggtggtgacacggacatgactgat
tacgtggcctatgtggccaaggaccccatcaaccagagagcctgccacatcttggaatgc
tgtgaaggtcttgcccagagcgtcatcagcaccgtagggcaagcctttgagctgcgcttc
aagcaatacctgcacagtccgcccaaggcggtagtgccccctgaaaggctgactgggctg
gaggagttggcctggggagatgatgacgctgctgcagaccacaattactacaacagcatt
ccgggaaaggagccacccctgggcgggctggtggactccagactggctgtcacacagccc
tgtgcgctggcgacactcgggggccttggacagggaatgacaccagtatggagagatgcc
cgtggcttgccttgggacatgggcccctctggagcagccccaccgggggatggctacgtg
caggcagatgcccgagggccacatgactacgaggagcacctgtatgtcaatacccagggc
ctggatgctgtggagcttgaggacaccgccgaggcacctctgcagtttgaggacagcccc
aagaaggacctgtttgacatgcgaccctttgaagatgccctgaagttgcacgcgtgctca
gtggcagccggcatcactgcagcctcaccccctctggaagaccagtggcccagtccccct
acccgcagggcccccattgcacccacagaggagcaattgaggcaggagccctggtaccac
ggacgaatgagccgtcgggctgcagagaagctgcttcgggccgatggggacttccttgtg
agagacagcgtcaccaacccggggcagtatgtcctcacgggcatgcatgcggggcagccc
aagcacctgctgctggtggaccccgagggtgtggtgcggacgaaagatgtgttgtttgag
agcatcagccacctcatagactatcacctgaagaatgggctgcctatcgtggctgctgag
agcgagctgcatctgcggggagtggtctctcgggagccatga

KEGG   Mus musculus (mouse): 271849
Entry
271849            CDS       T01002                                 

Gene name
Shc4, 6230417E10Rik, 9930029B02Rik, Gm685, RaLP
Definition
(RefSeq) SHC (Src homology 2 domain containing) family, member 4
  KO
K17449  SHC-transforming protein 4
Organism
mmu  Mus musculus (mouse)
Pathway
mmu01521  EGFR tyrosine kinase inhibitor resistance
mmu01522  Endocrine resistance
mmu04012  ErbB signaling pathway
mmu04014  Ras signaling pathway
mmu04062  Chemokine signaling pathway
mmu04072  Phospholipase D signaling pathway
mmu04510  Focal adhesion
mmu04650  Natural killer cell mediated cytotoxicity
mmu04722  Neurotrophin signaling pathway
mmu04910  Insulin signaling pathway
mmu04915  Estrogen signaling pathway
mmu04917  Prolactin signaling pathway
mmu04926  Relaxin signaling pathway
mmu04935  Growth hormone synthesis, secretion and action
mmu05034  Alcoholism
mmu05100  Bacterial invasion of epithelial cells
mmu05206  MicroRNAs in cancer
mmu05214  Glioma
mmu05220  Chronic myeloid leukemia
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    271849 (Shc4)
   04014 Ras signaling pathway
    271849 (Shc4)
   04072 Phospholipase D signaling pathway
    271849 (Shc4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    271849 (Shc4)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    271849 (Shc4)
   04062 Chemokine signaling pathway
    271849 (Shc4)
  09152 Endocrine system
   04910 Insulin signaling pathway
    271849 (Shc4)
   04915 Estrogen signaling pathway
    271849 (Shc4)
   04917 Prolactin signaling pathway
    271849 (Shc4)
   04926 Relaxin signaling pathway
    271849 (Shc4)
   04935 Growth hormone synthesis, secretion and action
    271849 (Shc4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    271849 (Shc4)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    271849 (Shc4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    271849 (Shc4)
   05226 Gastric cancer
    271849 (Shc4)
   05214 Glioma
    271849 (Shc4)
   05220 Chronic myeloid leukemia
    271849 (Shc4)
   05224 Breast cancer
    271849 (Shc4)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    271849 (Shc4)
  09165 Substance dependence
   05034 Alcoholism
    271849 (Shc4)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    271849 (Shc4)
   01522 Endocrine resistance
    271849 (Shc4)
SSDB
Motif
Pfam: PID SH2 Delta_lysin
Other DBs
NCBI-GeneID: 271849
NCBI-ProteinID: NP_950187
MGI: 2655364
Ensembl: ENSMUSG00000035109
Vega: OTTMUSG00000015349
UniProt: Q6S5L9 Q8CB26
Position
2; 2 F1
AA seq 626 aa
MRERSQDSQAGLTLYVGLFGHLGMLHRTKYSRFRNESITSLDEGSPGGSVGNKGSSPPPY
PALAPHLPTEDATVSSQESPTALCTLIPRMASMKLANPITFLGLKTFCLGTKQVSRLKLQ
ENQDQTPSRPASPESNLNRTGPAPAPDPDQVGRRPTSLRPDTCPLPGPGEPSPRSKQDGP
PLQHLLGNGLNYCVRYMGCIEVLQSMRSLDFGMRTQVTREAISRLCEAVPGAHGAIKKRK
APVKFLTTVLGKSNLQFSGMNIKLTVSTSSLTLMNLDNQQIIANHQMQSISFASGGDPDT
TDYVAYVAKDPVNQRACHILECRSGMAQDVISTIGQAFELRFKQYLKNPSLNTWEREEVL
VDGAPEDRDHDYYNSIPGKQPPEGGISDVRIQAQATDQMAYCPIRCEKLCYLPGNSTCSG
VYKNCMGRSRPIGIPHERAGQGDTPSLRHFWRVDLFDDPCYVNTQALQSMHSYAGNQSSA
LPQGSPWHLGKAPETVQPGATAKPGSALALPHIRQQLWDEECFHGKLSRGAAEKLLVKDG
DFLVRESVTSPGQFVLSGLQGGQAKHLLLVDPEGKVRTKDHVFDNVGHLIKYHMDNNLPI
ISSGSEVRLKQPIRKYDNTGLLPPKK
NT seq 1881 nt   +upstreamnt  +downstreamnt
atgcgagaacgcagccaggacagccaggcaggactcacgctgtatgtaggactctttggg
cacctggggatgcttcacaggaccaagtacagccgctttcggaacgagtccatcacgtct
ttggacgaagggagccccggaggctccgttggaaacaagggctcgtcgccgcctccctac
ccagccctggcccctcacctgccgactgaggatgccactgtgtccagccaggagagcccc
acggcgctgtgcaccttgattccccgtatggcaagcatgaagctggccaaccccatcact
tttctgggtctgaaaaccttctgcttgggtacgaaacaggtgagccggttgaagctccaa
gagaaccaggatcagactccaagccgtccagcgtccccagaatccaatctaaacaggact
ggacctgcacctgcaccggatccggaccaggtgggacgcaggcccacctctttgcgtcct
gatacttgcccactgcctggccctggagaaccaagccccaggagcaagcaggacgggccc
cctctgcagcacctgttggggaacggtctgaactactgtgtgcggtacatgggctgcatt
gaagtgctgcaatcaatgaggtcactggattttggaatgagaacccaagttacaagggaa
gcaataagtcgcctgtgtgaagctgtccccggggcccatggagccattaaaaaacgaaag
gctcccgttaagttcctgacaacggttcttggcaaaagcaatcttcagttttcaggaatg
aatataaaactgactgtttcaacaagcagcctcacactgatgaaccttgacaaccaacag
attattgcaaatcaccaaatgcaatcgatttcatttgcctctggaggggaccctgatacc
acagactatgttgcctatgtagctaaagatccagtcaaccaacgagcgtgccacatactg
gagtgtcgcagtggaatggcccaagacgtcataagcaccatagggcaggcctttgaactc
cggttcaaacagtacttgaaaaatccttccttgaacacttgggaaagggaggaggtactt
gttgatggtgcccctgaagacagagaccatgactattacaactccatcccggggaagcag
ccacctgaaggcggcatttcagatgtgcgcatccaggctcaagctacagaccaaatggca
tactgccctatccggtgtgaaaagttgtgctatttgcctgggaactccacgtgcagcggt
gtgtataagaactgtatgggacggagcaggccaataggtatcccgcacgagagagcgggg
cagggtgacacaccatcgctgaggcacttctggagagtggatctctttgacgacccctgc
tatgtcaatacacaggctcttcagagtatgcacagctatgctggaaatcaaagctcagct
ctgccacaggggagcccctggcacctcggaaaggcaccagaaactgtgcagcctggagcc
acggccaagcctgggagcgcactcgctttgccacacattaggcagcagctgtgggacgag
gagtgcttccatggcaagctgagcagaggggcagcggagaaacttttggtgaaggatggg
gactttttggttcgagagagtgtgacatctcccggccagtttgtactgagtggactgcaa
ggtggccaggccaagcatcttctcttggtggatccagaaggcaaggtgaggaccaaggac
catgtgtttgataatgttggccaccttatcaaataccatatggataataatttgccaatc
atctcttctggaagtgaagtacgccttaaacaaccaataagaaaatatgataacacagga
cttttgccccccaagaaatga

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