KEGG   Miniopterus natalensis (Natal long-fingered bat): 107536369
Entry
107536369         CDS       T05883                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mna  Miniopterus natalensis (Natal long-fingered bat)
Pathway
mna00562  Inositol phosphate metabolism
mna01100  Metabolic pathways
mna04015  Rap1 signaling pathway
mna04020  Calcium signaling pathway
mna04022  cGMP-PKG signaling pathway
mna04062  Chemokine signaling pathway
mna04070  Phosphatidylinositol signaling system
mna04071  Sphingolipid signaling pathway
mna04072  Phospholipase D signaling pathway
mna04081  Hormone signaling
mna04082  Neuroactive ligand signaling
mna04261  Adrenergic signaling in cardiomyocytes
mna04270  Vascular smooth muscle contraction
mna04310  Wnt signaling pathway
mna04371  Apelin signaling pathway
mna04540  Gap junction
mna04611  Platelet activation
mna04613  Neutrophil extracellular trap formation
mna04621  NOD-like receptor signaling pathway
mna04713  Circadian entrainment
mna04720  Long-term potentiation
mna04723  Retrograde endocannabinoid signaling
mna04724  Glutamatergic synapse
mna04725  Cholinergic synapse
mna04726  Serotonergic synapse
mna04728  Dopaminergic synapse
mna04730  Long-term depression
mna04742  Taste transduction
mna04750  Inflammatory mediator regulation of TRP channels
mna04911  Insulin secretion
mna04912  GnRH signaling pathway
mna04915  Estrogen signaling pathway
mna04916  Melanogenesis
mna04918  Thyroid hormone synthesis
mna04919  Thyroid hormone signaling pathway
mna04921  Oxytocin signaling pathway
mna04922  Glucagon signaling pathway
mna04924  Renin secretion
mna04925  Aldosterone synthesis and secretion
mna04926  Relaxin signaling pathway
mna04927  Cortisol synthesis and secretion
mna04928  Parathyroid hormone synthesis, secretion and action
mna04929  GnRH secretion
mna04933  AGE-RAGE signaling pathway in diabetic complications
mna04934  Cushing syndrome
mna04935  Growth hormone synthesis, secretion and action
mna04961  Endocrine and other factor-regulated calcium reabsorption
mna04970  Salivary secretion
mna04971  Gastric acid secretion
mna04972  Pancreatic secretion
mna04973  Carbohydrate digestion and absorption
mna05010  Alzheimer disease
mna05016  Huntington disease
mna05017  Spinocerebellar ataxia
mna05022  Pathways of neurodegeneration - multiple diseases
mna05142  Chagas disease
mna05143  African trypanosomiasis
mna05146  Amoebiasis
mna05163  Human cytomegalovirus infection
mna05200  Pathways in cancer
mna05415  Diabetic cardiomyopathy
mna05417  Lipid and atherosclerosis
Module
mna_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mna00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    107536369 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    107536369 (PLCB1)
   04310 Wnt signaling pathway
    107536369 (PLCB1)
   04371 Apelin signaling pathway
    107536369 (PLCB1)
   04020 Calcium signaling pathway
    107536369 (PLCB1)
   04070 Phosphatidylinositol signaling system
    107536369 (PLCB1)
   04072 Phospholipase D signaling pathway
    107536369 (PLCB1)
   04071 Sphingolipid signaling pathway
    107536369 (PLCB1)
   04022 cGMP-PKG signaling pathway
    107536369 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    107536369 (PLCB1)
   04081 Hormone signaling
    107536369 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107536369 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107536369 (PLCB1)
   04613 Neutrophil extracellular trap formation
    107536369 (PLCB1)
   04621 NOD-like receptor signaling pathway
    107536369 (PLCB1)
   04062 Chemokine signaling pathway
    107536369 (PLCB1)
  09152 Endocrine system
   04911 Insulin secretion
    107536369 (PLCB1)
   04922 Glucagon signaling pathway
    107536369 (PLCB1)
   04929 GnRH secretion
    107536369 (PLCB1)
   04912 GnRH signaling pathway
    107536369 (PLCB1)
   04915 Estrogen signaling pathway
    107536369 (PLCB1)
   04921 Oxytocin signaling pathway
    107536369 (PLCB1)
   04926 Relaxin signaling pathway
    107536369 (PLCB1)
   04935 Growth hormone synthesis, secretion and action
    107536369 (PLCB1)
   04918 Thyroid hormone synthesis
    107536369 (PLCB1)
   04919 Thyroid hormone signaling pathway
    107536369 (PLCB1)
   04928 Parathyroid hormone synthesis, secretion and action
    107536369 (PLCB1)
   04916 Melanogenesis
    107536369 (PLCB1)
   04924 Renin secretion
    107536369 (PLCB1)
   04925 Aldosterone synthesis and secretion
    107536369 (PLCB1)
   04927 Cortisol synthesis and secretion
    107536369 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107536369 (PLCB1)
   04270 Vascular smooth muscle contraction
    107536369 (PLCB1)
  09154 Digestive system
   04970 Salivary secretion
    107536369 (PLCB1)
   04971 Gastric acid secretion
    107536369 (PLCB1)
   04972 Pancreatic secretion
    107536369 (PLCB1)
   04973 Carbohydrate digestion and absorption
    107536369 (PLCB1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    107536369 (PLCB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    107536369 (PLCB1)
   04725 Cholinergic synapse
    107536369 (PLCB1)
   04728 Dopaminergic synapse
    107536369 (PLCB1)
   04726 Serotonergic synapse
    107536369 (PLCB1)
   04720 Long-term potentiation
    107536369 (PLCB1)
   04730 Long-term depression
    107536369 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    107536369 (PLCB1)
  09157 Sensory system
   04742 Taste transduction
    107536369 (PLCB1)
   04750 Inflammatory mediator regulation of TRP channels
    107536369 (PLCB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    107536369 (PLCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107536369 (PLCB1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    107536369 (PLCB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    107536369 (PLCB1)
   05142 Chagas disease
    107536369 (PLCB1)
   05143 African trypanosomiasis
    107536369 (PLCB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107536369 (PLCB1)
   05016 Huntington disease
    107536369 (PLCB1)
   05017 Spinocerebellar ataxia
    107536369 (PLCB1)
   05022 Pathways of neurodegeneration - multiple diseases
    107536369 (PLCB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    107536369 (PLCB1)
   05415 Diabetic cardiomyopathy
    107536369 (PLCB1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    107536369 (PLCB1)
   04934 Cushing syndrome
    107536369 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mna04131]
    107536369 (PLCB1)
Enzymes [BR:mna01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     107536369 (PLCB1)
Membrane trafficking [BR:mna04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    107536369 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    107536369 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 107536369
NCBI-ProteinID: XP_016067519
Position
Unknown
AA seq 1216 aa
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRSDPQGFFFYWTDQNKE
TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEHRMITVVYGPDLVNISYLNLV
AFQEEVAKEWTNEVFSLATNLLAHNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNTSLAKKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTCSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNRSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGSKFIGHRILPVQAVRPGYHYISLRNER
NQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLDDEEEARR
EADPGETPSEAPSEARTTPAENGVNHTTSLAPKPPSQALHSQPAPGSVKAPAKTEDLIQS
VLTEVEAQTIEELKQQKAFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
RRRVALEKTAKKDSKKRSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQSSQLKKLKELCEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSAPSSLASDPGKLNHRPPSS
EELEGDHPGKEFDTPL
NT seq 3651 nt   +upstreamnt  +downstreamnt
atggccggggctcagcccggagtgcacgctctgcaactcaagccggtgtgtgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgactccactatcgtcactcca
attattttgaggtctgaccctcagggatttttcttttactggacagatcaaaacaaggag
acggagctgctagatctcagcctcgtcaaggatgccagatgtgggagacatgcaaaggct
cccaaggaccccaaactacgtgaacttctggatgtggggaacatcggacgtctggaacat
cgcatgataacggtggtgtatgggcccgacttagttaacatctcctatttgaacctcgtg
gctttccaagaagaagtggccaaggaatggacaaatgaggttttcagtttggcaacaaac
ctgctggcccataacatgtccagggacgcatttctggaaaaagcctatactaaacttaag
ctgcaagtcactccagaagggcgtattcctctcaaaaacatctaccgcttgttttcagct
gaccggaaacgagttgaaaccgctttagaggcttgtagtcttccatcttcaaggaatgat
tcgatacctcaagaagatttcactccagaagtgtaccgagttttcctgaacaacctttgc
cctcggcctgaaattgataacatcttttctgaatttggtgccaaaagcaagccatatctt
accgttgatcagatgatggatttcatcaacctcaagcagcgagatccccggctaaatgaa
atactttaccctcctttaaagcaagagcaagtccaagtattgattgagaagtatgaaccc
aacactagcctcgccaagaaaggacagatatccgtggacggctttatgcgctacctgagt
ggggaagaaaacggagtggtgtcacccgagaagctggatctgaatgaagatatgtcgcag
cccctttctcactatttcatcaattcctcgcacaacacctacctcacagctggacagctg
gctggaaactcctccgtcgagatgtatcgtcaagtgcttctttctggttgtcgctgtgtg
gagttggactgctggaaaggacggaccgcagaggaggaaccagtcatcactcatgggttc
accatgacgaccgaaatatccttcaaggaagtgatagaagcaatcgctgagtgtgcattt
aagacttcacctttcccaatcctcctttcatttgagaatcacgtggattccccgaagcag
caggctaagatggccgagtattgccgactgatctttggggacgcccttctcatggagcca
ctggagaaatacccactggaatctggagttcctcttccaagccctatggatttaatgtac
aaaattttggtgaaaaataagaagaaatcgcacaagtcgtcagaaggaagtggcaaaaag
aagctctcagaacaagcctccaacacgtgcagcgactcctccagcgtgttcgagccctcg
tctcccggagccggggaggctgatacggagagcgacgatgacgatgatgatgatgactgt
aaaaagtcttcaatggatgagggtactgctgggagtgaggccatggccacagaagagatg
tctaacctggtgaactatattcagcccgtcaagtttgagtcatttgaaatttccaaaaaa
agaaatagaagttttgaaatgtcttccttcgtggaaaccaaaggacttgagcaactgacg
aagtctccggtggaattcgtagaatataacaaaatgcagcttagcaggatatatccgaaa
ggaacacgtgtagattcgtccaactatatgcctcagctcttctggaatgcaggctgtcag
atggttgcccttaatttccaaaccgtggacctggctatgcagatcaatatggggatgtat
gagtacaatgggaagagcggctacaggctgaagccagagtttatgcggaggcctgacaag
cactttgacccgttcactgagggcatcgtggatgggatcgtggccaacacgttatccgtt
aagattatttcgggccagttcctttctgataagaaagtcgggacgtatgtggaagtggat
atgtttggcttgcctgtggacacaaggaggaaagcgtttaagaccaagacatcccaggga
aatgctgtaaaccccgtctgggaggaagagcccattgtgttcaaaaaggtggttcttccg
tcgctggcctgcctgaggatcgccgcttacgaagaggggagcaagtttatcggccaccgg
atcttgccggtgcaagcagttcggccaggctatcactacatctctctgaggaatgagagg
aaccagcccctgatgctcccggctgtcttcgtctacatagaggtgaaagactatgtccca
gatacctatgcagatgtgattgaagctctgtccaacccgatccgctacgtgaatctgatg
gagcagagagctaagcagctggccgctttgacgctggacgatgaagaggaggcaaggaga
gaggctgatcctggagaaacaccgtcagaggctccgagtgaagccaggacgaccccagca
gaaaatggagtgaatcacactacatccctggcacccaaacctccctctcaggctctccac
agccaacccgcgccaggctctgtgaaggcacctgccaaaacagaagatcttatacagagc
gttttaacagaagtggaagcgcagactattgaagagctaaagcaacagaaggcgtttgta
aaacttcaaaagaagcactacaaagaaatgaaagacctggtgaagagacaccacaagaaa
accacggaccttatcaaggaacacactaccaagtacaatgagattcagaatgactaccta
agaaggagggtggctttggaaaagacagccaagaaggacagtaagaaaagatcggaaccc
agcagccctgaccacggctcatccaccattgagcaagatcttgctgccctggatgccgaa
atgacccaaaagttaatagacttgaaggacaaacaacaacagcaactgctcaatcttcga
caagagcagtactacagtgaaaaataccagaagcgagaacatattaaactgcttatccag
aagctgacggacgtcgccgaggaatgccagagcagccagctgaagaagctcaaagagctg
tgtgagaaagagaagaaggagttaaagaagaaaatggataaaaagaggcaggagaagata
acagaagcgaagtccaaagacaaaagccagatggaagaggagaagacagagatgatccgg
tcctacatccaggaggtggtgcagtacatcaagaggttagaagaggcacaaagtaaacgg
caagaaaaactggtagagaaacacaaggagatacgtcagcagatcctggatgaaaagccc
aagctgcaggtggaactggagcaagagtaccaagacaagttcaaaagactgcccctggag
attctggagttcgtacaggaagccatgaaagggaagatcagtgaggacagcaatcacagt
tctgccccttcctccctggcctcagaccctggaaaactgaaccacaggcctccctccagt
gaggagctggaaggagatcacccaggaaaagagttcgatactcctctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (10)   

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