KEGG   Miniopterus natalensis (Natal long-fingered bat): 107542967
Entry
107542967         CDS       T05883                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mna  Miniopterus natalensis (Natal long-fingered bat)
Pathway
mna00562  Inositol phosphate metabolism
mna01100  Metabolic pathways
mna04015  Rap1 signaling pathway
mna04020  Calcium signaling pathway
mna04022  cGMP-PKG signaling pathway
mna04062  Chemokine signaling pathway
mna04070  Phosphatidylinositol signaling system
mna04071  Sphingolipid signaling pathway
mna04072  Phospholipase D signaling pathway
mna04081  Hormone signaling
mna04082  Neuroactive ligand signaling
mna04261  Adrenergic signaling in cardiomyocytes
mna04270  Vascular smooth muscle contraction
mna04310  Wnt signaling pathway
mna04371  Apelin signaling pathway
mna04540  Gap junction
mna04611  Platelet activation
mna04613  Neutrophil extracellular trap formation
mna04621  NOD-like receptor signaling pathway
mna04713  Circadian entrainment
mna04720  Long-term potentiation
mna04723  Retrograde endocannabinoid signaling
mna04724  Glutamatergic synapse
mna04725  Cholinergic synapse
mna04726  Serotonergic synapse
mna04728  Dopaminergic synapse
mna04730  Long-term depression
mna04742  Taste transduction
mna04750  Inflammatory mediator regulation of TRP channels
mna04911  Insulin secretion
mna04912  GnRH signaling pathway
mna04915  Estrogen signaling pathway
mna04916  Melanogenesis
mna04918  Thyroid hormone synthesis
mna04919  Thyroid hormone signaling pathway
mna04921  Oxytocin signaling pathway
mna04922  Glucagon signaling pathway
mna04924  Renin secretion
mna04925  Aldosterone synthesis and secretion
mna04926  Relaxin signaling pathway
mna04927  Cortisol synthesis and secretion
mna04928  Parathyroid hormone synthesis, secretion and action
mna04929  GnRH secretion
mna04933  AGE-RAGE signaling pathway in diabetic complications
mna04934  Cushing syndrome
mna04935  Growth hormone synthesis, secretion and action
mna04961  Endocrine and other factor-regulated calcium reabsorption
mna04970  Salivary secretion
mna04971  Gastric acid secretion
mna04972  Pancreatic secretion
mna04973  Carbohydrate digestion and absorption
mna05010  Alzheimer disease
mna05016  Huntington disease
mna05017  Spinocerebellar ataxia
mna05022  Pathways of neurodegeneration - multiple diseases
mna05142  Chagas disease
mna05143  African trypanosomiasis
mna05146  Amoebiasis
mna05163  Human cytomegalovirus infection
mna05200  Pathways in cancer
mna05415  Diabetic cardiomyopathy
mna05417  Lipid and atherosclerosis
Module
mna_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mna00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    107542967 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    107542967 (PLCB2)
   04310 Wnt signaling pathway
    107542967 (PLCB2)
   04371 Apelin signaling pathway
    107542967 (PLCB2)
   04020 Calcium signaling pathway
    107542967 (PLCB2)
   04070 Phosphatidylinositol signaling system
    107542967 (PLCB2)
   04072 Phospholipase D signaling pathway
    107542967 (PLCB2)
   04071 Sphingolipid signaling pathway
    107542967 (PLCB2)
   04022 cGMP-PKG signaling pathway
    107542967 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    107542967 (PLCB2)
   04081 Hormone signaling
    107542967 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107542967 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107542967 (PLCB2)
   04613 Neutrophil extracellular trap formation
    107542967 (PLCB2)
   04621 NOD-like receptor signaling pathway
    107542967 (PLCB2)
   04062 Chemokine signaling pathway
    107542967 (PLCB2)
  09152 Endocrine system
   04911 Insulin secretion
    107542967 (PLCB2)
   04922 Glucagon signaling pathway
    107542967 (PLCB2)
   04929 GnRH secretion
    107542967 (PLCB2)
   04912 GnRH signaling pathway
    107542967 (PLCB2)
   04915 Estrogen signaling pathway
    107542967 (PLCB2)
   04921 Oxytocin signaling pathway
    107542967 (PLCB2)
   04926 Relaxin signaling pathway
    107542967 (PLCB2)
   04935 Growth hormone synthesis, secretion and action
    107542967 (PLCB2)
   04918 Thyroid hormone synthesis
    107542967 (PLCB2)
   04919 Thyroid hormone signaling pathway
    107542967 (PLCB2)
   04928 Parathyroid hormone synthesis, secretion and action
    107542967 (PLCB2)
   04916 Melanogenesis
    107542967 (PLCB2)
   04924 Renin secretion
    107542967 (PLCB2)
   04925 Aldosterone synthesis and secretion
    107542967 (PLCB2)
   04927 Cortisol synthesis and secretion
    107542967 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107542967 (PLCB2)
   04270 Vascular smooth muscle contraction
    107542967 (PLCB2)
  09154 Digestive system
   04970 Salivary secretion
    107542967 (PLCB2)
   04971 Gastric acid secretion
    107542967 (PLCB2)
   04972 Pancreatic secretion
    107542967 (PLCB2)
   04973 Carbohydrate digestion and absorption
    107542967 (PLCB2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    107542967 (PLCB2)
  09156 Nervous system
   04724 Glutamatergic synapse
    107542967 (PLCB2)
   04725 Cholinergic synapse
    107542967 (PLCB2)
   04728 Dopaminergic synapse
    107542967 (PLCB2)
   04726 Serotonergic synapse
    107542967 (PLCB2)
   04720 Long-term potentiation
    107542967 (PLCB2)
   04730 Long-term depression
    107542967 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    107542967 (PLCB2)
  09157 Sensory system
   04742 Taste transduction
    107542967 (PLCB2)
   04750 Inflammatory mediator regulation of TRP channels
    107542967 (PLCB2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    107542967 (PLCB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107542967 (PLCB2)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    107542967 (PLCB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    107542967 (PLCB2)
   05142 Chagas disease
    107542967 (PLCB2)
   05143 African trypanosomiasis
    107542967 (PLCB2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    107542967 (PLCB2)
   05016 Huntington disease
    107542967 (PLCB2)
   05017 Spinocerebellar ataxia
    107542967 (PLCB2)
   05022 Pathways of neurodegeneration - multiple diseases
    107542967 (PLCB2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    107542967 (PLCB2)
   05415 Diabetic cardiomyopathy
    107542967 (PLCB2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    107542967 (PLCB2)
   04934 Cushing syndrome
    107542967 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mna04131]
    107542967 (PLCB2)
Enzymes [BR:mna01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     107542967 (PLCB2)
Membrane trafficking [BR:mna04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    107542967 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    107542967 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh C2 EF-hand_like AAA_13 MMACHC
Other DBs
NCBI-GeneID: 107542967
NCBI-ProteinID: XP_016075872
Position
Unknown
AA seq 1166 aa
MSVLNPVLLPPKVKAYLISGEHFIKWDDETTVASPVMLSVDPKGYYLYWTYQSKEKEFLD
ITSIRDTRFGKFAKIPKSQKLRDVFNLDFPDNTFLLKAFTVVSGPDMVDLTFHNFVSCKE
NVGKDWAEDILALVKHPLSANAPRATFLDKILVKLKMQLNPEGKIPVKNLFQMFPADRKR
VEAALSACHLPKGKNDAINPEDFPQSVYKSFLLNLCPRPEIDEIFTSHHAKAKPYMTKEH
LTKFINQKQRDPRLNSLLFPPARPDQVQGLIDKYEPSGINVQRGQLSPQGMVWFLCGPEN
SVLAQDKLLVHQDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLAGCRCVELDC
WKGKLPEEEPIITHGFTMTTDIYFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKM
AEYCRTMFGDMLLTEPLEKFPLKPGSPLPSPEDLRGKILIKNKKNQFLGPAAPSKELGGE
AEGSCPPSAPVAEDTVLAAEEGAELEEQVEEEESELGNLDEEEMRKMQSDEGTAGLEVTA
YEEMSSLVNYIQPTKFISFEFSAQKNQSYVISSFTELKAYDLLSKAAVQFVDYNKRQMSR
IYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMR
RPDKQFNPFSVDGIDVVVATTLSIKVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKL
SPSANSINPVWNEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINILNSGYHHLCL
RSESNMPLTMPALFVLLEMKDYVPDTWADLTVALANPIKFFSAHDKKSVKLKEAMGGLPE
KPFFSGSPVASQVNGAPASNGSAEPRTASLEELRELKGVVKLQRRQEKELRELERRGARR
WEELLQRGAAQLXXXXXXXXGGLGGCRLGPGKGSRKKRTQPREEVAGSRLGEGPEGADPR
AHELRDRLELELQQQGKEHYECVLKLKEQHLAEKIAKMMELAREKQAAELKTLKETSEND
TKEMKKKLEAKRLERIQAMMKSTTDKMAQERLKKEINNSHIQEVVQVINRMTESLERHQE
KLEEKQAACLEQIREMEKQFQQEALAEYEAKMKGLEAEVKESVRTCLRACFPSEAEDKLE
RPCGASRELCEQEPLTVNTDTQESCL
NT seq 3501 nt   +upstreamnt  +downstreamnt
atgtctgtgctcaaccctgtcctgctgccccccaaagtgaaggcctacctgatctccggg
gagcatttcatcaaatgggacgatgaaacaacagtagcctccccggttatgctctctgtg
gatcccaagggctattacttatactggacatatcagagcaaggaaaaggagtttctggat
atcaccagcatccgggacacccgctttgggaagtttgccaagattcccaagagccagaag
ctccgggatgtcttcaacctggattttcctgacaacaccttcctgctgaaggcattcact
gtggtgtctggccctgacatggtggacctcaccttccacaactttgtctcctgcaaagag
aatgtgggcaaggactgggctgaagatatactggctctggtcaaacacccgctgtcagcc
aacgccccccgcgccaccttcctggacaagattctggtgaagctcaagatgcagctcaat
cctgaagggaagattcctgtgaagaatttattccagatgtttcctgctgaccgcaagcgt
gtagaagctgccctcagtgcctgccacctccccaaaggcaaaaatgatgccatcaatcct
gaggacttcccacaatctgtctacaagagtttcctcttgaacctctgcccccggccagaa
atagatgagatcttcacttcccaccatgccaaggccaaaccctacatgaccaaggagcac
ttgaccaaatttatcaaccagaaacagagggatcctcgcctcaactccttattgttccca
ccagcgcggcctgaccaggtgcagggcctcattgacaaatatgagcccagtggcatcaac
gtgcagaggggccagctgtcaccccagggcatggtgtggtttctctgtgggccggagaac
agcgtgctggcccaagacaagctgctggttcaccaggacatgacgcagccgctcaatcat
tacttcatcaactcctcgcacaacacctacctgacagccggccagttctcaggcctctcc
tctgctgagatgtaccgccaggtgctgctggctggctgtcgctgcgtggagctggactgc
tggaaggggaagctccccgaagaggagcctattatcacccacggctttaccatgaccaca
gacatctacttcaaggaagcaattgaggcgattgcagaaagtgcctttaagacctccccc
tatcctgtcatcctgtcgtttgaaaaccacgtggactcaccccgccaacaggccaagatg
gctgagtactgccggaccatgtttggtgatatgctgctcacggagcccctggaaaagttt
ccactgaaaccaggcagccccctgcccagccccgaggatctccgtggcaagatcctcatc
aaaaacaagaagaaccagtttttgggcccagcagcccccagcaaggagctgggcggggag
gctgagggcagctgcccacccagtgcccctgtggcggaggacaccgtgttggctgctgag
gaaggggctgagctggaggagcaggtggaggaggaggagtcggagttgggaaacctggat
gaagaagagatgaggaagatgcagtcagatgagggcacagcgggcctggaggtgacggcc
tatgaggagatgtccagcctggttaactacatccagcccaccaagttcatctcctttgag
ttctctgcccagaagaaccaaagttatgtcatctcttcctttacggagctcaaggcttat
gacctgctctccaaggctgcagtgcagtttgttgactacaacaagcgccagatgagccgc
atttacccaaagggcacccgcatggactcctccaattacatgccccagatgttctggaat
gctggttgccagatggtcgccctcaacttccagacaatggacctgcccatgcaacagaac
atggcgctatttgagttcaatgggcagagtggctaccttctcaagcatgagttcatgcgc
cggccagacaagcagttcaaccccttctcggtggatggcatcgacgtggtggtagccacc
accctttccattaaggtaatctctgggcagttcctgtcagaacgcagcgtgcgcacctat
gtggaagtggagctgtttggcctacctggggaccccaagaggcgctatcgcaccaagctg
tcacccagtgccaactccatcaatcctgtctggaatgaggagccctttgtctttgagaag
atcttgatgcctgagctggcctccctcagggtggctgtgatggaggaaggcaacaagttt
cttggacaccgcatcatccccatcaatattctgaattctggataccaccatctgtgcctg
cgcagtgagagcaacatgcccctcaccatgcctgcgctctttgttctcctggagatgaag
gactatgtacctgacacctgggcagatctcaccgtggccctcgccaatcccatcaagttc
ttcagcgcccatgataagaagtctgtgaagctcaaggaagccatgggaggtctgcctgag
aagcccttcttttccgggagtccagttgccagccaggtcaacggggccccggccagcaat
gggtcagcagagccgcggaccgccagcctggaggagctgcgggagctgaagggcgtcgtg
aagctgcagcggcggcaggagaaggagctgcgggagctggagcggcgcggcgcgcggcgc
tgggaggagctgctgcagcggggcgcggcgcagctnnnnnnnnnnnnnnnnnnnnnnngg
ggcggcctcgggggctgcaggctcggcccgggcaagggctcccgcaagaagaggacccag
cccagggaggaggtcgccgggtccaggctgggcgagggccccgagggcgcggacccgcgc
gcgcatgagctgagggacaggctggagctggagctgcagcagcagggcaaggagcactac
gagtgtgtcctgaagctcaaggagcagcacctggccgagaaaattgccaagatgatggag
ctggccagagagaaacaggctgcagagcttaagaccctcaaggagacctcagagaatgac
accaaagagatgaagaagaagctggaggccaagaggctggagcggatccaggccatgatg
aagtctaccactgacaagatggcccaggagaggttgaagaaagagattaacaactcccac
atccaggaggtggttcaggtcatcaaccggatgacagagagcctggagaggcaccaggag
aagctggaggagaagcaggcagcctgcctggaacagatccgggagatggagaagcagttc
cagcaggaggcgctggcagagtatgaggccaagatgaagggcctggaggctgaggtgaag
gagtcggtgaggacctgcctcagggcctgcttcccctctgaggctgaggacaagcttgag
aggccctgtggggcctccagggagctgtgtgagcaggaaccacttacagtcaacacagac
acccaggagagctgcctctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (13)   

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