KEGG   Macaca nemestrina (pig-tailed macaque): 105486099
Entry
105486099         CDS       T08765                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
mni  Macaca nemestrina (pig-tailed macaque)
Pathway
mni04310  Wnt signaling pathway
mni04390  Hippo signaling pathway
mni04519  Cadherin signaling
mni04550  Signaling pathways regulating pluripotency of stem cells
mni04810  Regulation of actin cytoskeleton
mni04934  Cushing syndrome
mni05010  Alzheimer disease
mni05022  Pathways of neurodegeneration - multiple diseases
mni05165  Human papillomavirus infection
mni05200  Pathways in cancer
mni05206  MicroRNAs in cancer
mni05210  Colorectal cancer
mni05213  Endometrial cancer
mni05217  Basal cell carcinoma
mni05224  Breast cancer
mni05225  Hepatocellular carcinoma
mni05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mni00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    105486099 (APC2)
   04390 Hippo signaling pathway
    105486099 (APC2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    105486099 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    105486099 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105486099 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105486099 (APC2)
   05206 MicroRNAs in cancer
    105486099 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105486099 (APC2)
   05225 Hepatocellular carcinoma
    105486099 (APC2)
   05226 Gastric cancer
    105486099 (APC2)
   05217 Basal cell carcinoma
    105486099 (APC2)
   05213 Endometrial cancer
    105486099 (APC2)
   05224 Breast cancer
    105486099 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    105486099 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105486099 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    105486099 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105486099 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mni01009]
    105486099 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mni03036]
    105486099 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:mni04812]
    105486099 (APC2)
Protein phosphatases and associated proteins [BR:mni01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     105486099 (APC2)
Chromosome and associated proteins [BR:mni03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    105486099 (APC2)
Cytoskeleton proteins [BR:mni04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     105486099 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC APC_r Arm Arm_APC_u3 Suppressor_APC SAMP ARM_ARMC5 ZER1-like_2nd SSNA1 PEA2_C Sec7-like_HUS Par-4_C PDC10_C HALZ CCDC138_cc
Other DBs
NCBI-GeneID: 105486099
NCBI-ProteinID: XP_011747092
Ensembl: ENSMNEG00000032973
Position
Unknown
AA seq 2441 aa
MTGEYMCVARWRREGRNRQAGQGRCEEGAQAGRGRWQRDGLPLVRLRQRRREEASAVGKG
TKREGGREEGLRQEGRAEGGGTGQLDRGRRPGWSQKTARGTKKLAALAEPRDGAGAAGAS
REQLKAAQGVRATQTLQELKMASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLE
TETSGMKEVLKHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPALGPEP
ASQTPEGSPVHGSGPSKDSFGELSRATIRLLEELDRERCLLLNEIEKEEKEKLWYYSQLQ
GLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLE
QIDKELLEAQDRVQQTEPQALLAVKSVPVDEDPETEVPTHPEDGTPQPGNSKVEVVFWLL
SMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAAAGGRAGAPGAPGA
KDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGAPEGGGA
SGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHKMTRDPLNL
ALRRYAGMTLTNLTFGDVANKATLCARRGCMEAIVAQLASDSEELHQVVSSILRNLSWRA
DINSKKVLREAGSVTALVQCVLRATKESTLKSVLSALWNLSAHSTENKAAICQVDGALGF
LVSTLTYKCQSNSLAIIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSHSLT
IVSNACGTLWNLSARSARDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPA
KHQAAATAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKHRPPAAEATSKKPLPP
LRHLDGLAQDYASDSGCFDDDDAPSSLAAAAATGEPASPAALSLFLGSPFLQGQALARTP
PTRRGGKEAEKDASGEAAVAAKAKAKLALAVARIDQLVEDISALHTSSDDSFSLSSGDPG
QEAPREGRAQSCSPCRGPEGGRREAGSRAHPLLRLKAAHASLSNDSLNSGSASDGYCPRE
HMLPCPLAALALRREDPRCGQPRPSRLDLDLPGSQAEPPAREATSADARVRTIKLSPTYQ
HVPLLEGASRAGAEPLAGPGTSPGARKQAWLPADHLSKVPEKLAAAPLSVASKALQKLVA
QEGPLSLSRCSSLSSLSSAGRPGPSEGGDLDDTDSSLEGLEEAGPGEAELDSVWRAPGAT
SLPVAIPAPRRNRGRGLGVEDATPSSSSENYVQETPLVLSRCSSVSSLGSFESPSIASSI
PSDPCSGQGSGTISPSELPDSPGQTMPPSRSKTPPLAPAPQGPPEASQFSLQWESYVKRF
LDIADCRERCRLPSELDAGSVRFTVEKPDENFSCASSLSALALHEHYVQQDVELRLLPSA
CPERGGGTGGAGLHFAGHRRREEGPAPTGSRPRGAADQELELLRECLGAAVPARLRKVAS
ALVPGRRALPVPVYMLVPAPARAQEDDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPG
GPEGRQRPTGRPTSARQAVGHRHKAGGAGRSVEQARGTGKNRAGLELPLGRPPSAPADKD
DSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAAAPTPTHRRTSAIPRALTRE
RLQGRKEAPAPSKAAPSAPPPTRAQPSLIADETPPCYSLSSSASSLSEPEPPEPPSVSPR
GQEPAVTKDPGPRGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDER
PAEGSREHGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSF
VSGLSVGSTLQPPKHRKGRQAGGEMGSARRPEKRGTASAKTSGSPRSPAGPEKPRGTQKT
TPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQSAAPAKVPSPGQQRS
RSLHRPGKTSELGTLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPL
PGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGRAGTE
AGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASA
PQGTSPRRGRPALPAVFLCSSRCEELRAAPRQAPARQRPPAARPGPGERPARRTSSESPS
RLPVRAPAARPETVKRYASLPHISVARRPDGAVPAAPAPADAARRSSDGEPRSLPRVAAP
GTTWRRIRDEDVPHILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTN
SSTSPSLESREPPGAPASGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHG
SPSRSARVPPFNYVPSPMVVAATTDSAAEKAPATSSATLLE
NT seq 7326 nt   +upstreamnt  +downstreamnt
atgacaggtgaatatatgtgtgttgccaggtggaggagggaggggagaaacaggcaggcc
ggacagggccgctgtgaggagggggctcaggctggcagggggaggtggcagagggatggg
ctgccattggtacgtctgagacaaaggcggagggaggaggcgagcgctgttgggaaagga
acaaagagggaaggggggcgtgaggaggggctccggcaggagggccgagccgagggagga
ggcaccggccagctggacagagggaggaggccaggctggagccagaagacggccagaggc
acaaagaagctagcggcactggcagaaccaagggatggggcaggggctgccggggccagc
agggagcagctgaaggctgcgcagggggtgcgggccacacagacgctgcaggagctgaag
atggcgagctccgtggcaccctacgagcagctggtgcggcaggtggaggccttgaaggct
gagaacagtcacctgaggcaggagctacgggacaactccagccacctgtccaagctggag
acagagacgtcaggcatgaaggaggtcctgaagcacctacagggaaaactggagcaggag
gcccgcgtgctggtgtcctcggggcagacggaggtgctggagcagttgaaggccctgcag
atggacatcaccagcctgtacaacctcaagttccagccgcccgccctgggcccggaacct
gcctcccagacccccgagggcagcccggtacacggctccgggccttccaaggacagcttt
ggggagctgagccgggccaccatccggctgctggaggaactggaccgggaacggtgtttg
ctgctgaatgagattgagaaggaggagaaggagaagctttggtactactctcagctgcag
ggcctgtccaagcgcctggacgagctgccgcacgtggagacgcagttctcgatgcagatg
gacttgatccggcagcaacttgagttcgaggcccagcacatccgctcgctgatggaggag
cgcttcggcacctcggacgagatggtgcagcgggcacagatccgcgcctcgcgcctggag
cagattgacaaggagctgctggaggcgcaggaccgagtgcagcagacagagccccaggcc
ttgctggcggtgaagtctgtgccggtggacgaggacccggagacagaggtccccacacac
cctgaggatggcacccctcaaccgggcaacagcaaggtggaggtggtcttctggctgttg
tccatgttggcgacgcgcgaccaggaggatacagcgcgcacgctactggccatgtcaagc
tcgcccgagagctgcgtggccatgcgccgctcgggctgtctgccactgctgctgcaaatc
ctccacggcactgaggccgcggccgggggtcgcgccggggccccaggagcaccgggcgcc
aaagacgcacgcatgcgcgccaacgcggcgctgcacaacatcgtcttctcgcagccggac
cagggcctggcacgcaaggagatgcgcgtcctgcacgtgctggagcagatccgtgcctac
tgcgagacctgctgggactggctgcaggcccgagacggcgcgcccgagggaggcggcgcc
agcggcgccccggtccccatcgagccgcagatctgccaggccacctgtgcggttatgaag
ctgtcctttgacgaggagtaccgccgtgccatgaacgagctgggtgggctgcaggccgtg
gcagagctgctgcaggttgactatgagatgcacaagatgacccgggacccgctgaacctg
gcgctgcgccgctacgcgggcatgaccctcaccaacctcacctttggggatgttgccaac
aaggccaccctgtgtgcgcgccggggctgcatggaggccatcgtggcccagctggcctcg
gacagtgaggagctccaccaggtggtgtccagcatccttcggaacttgtcctggagggcc
gacatcaacagcaagaaggtgctgagggaggcgggcagcgtgacagccctggtgcagtgt
gtcctgcgggccaccaaggagtccaccctgaagagtgtgctgagtgccctgtggaatctg
tctgcacacagcacggagaacaaggcggccatctgccaggtggacggcgccctgggcttc
ctggtgagcaccctgacctacaagtgccagagcaactcgctggccatcatcgagagcggc
ggcggcatcctccgcaacgtgtccagcctcatcgccacccgtgaggactacaggcaggtg
ctccgggatcacaactgcctgcagacgctgttgcagcatctgacctcgcacagcctgacc
atcgtgagcaacgcatgtggcacactctggaacctatcagcccgcagcgcgcgagaccag
gagctgctgtgggacctgggcgctgtgggcatgctgcgcaatctggtgcactccaaacac
aagatgatcgccatgggcagcgccgccgccctgcgcaacctgctcgcccatcgacctgcc
aagcaccaggcggccgccaccgccgtgtccccaggcagctgcgtgcccagcctgtacgtg
cgcaagcagcgggcgctggaggccgagctggacgcacggcacctggcgcaggcgctggag
cacctggagaagcaccgcccgccggcagccgaggccaccagcaagaagccgctgccgccc
ctgcgacacctggacggcctggcccaagactatgcttccgattctggctgctttgacgac
gacgatgcaccgtcatccctggccgcggccgcggccaccggggagccagccagccctgcc
gcgttgtccctcttcctgggcagccccttcctgcaggggcaggcgctggcccgcaccccg
cccacccgccgaggcggcaaggaggcagagaaggacgccagtggggaggcggccgtggcg
gccaaggccaaggccaagctggcgcttgcagtggcgcgcatcgaccagctggtggaggac
atctccgccctgcatacctcgtccgacgatagcttcagcctcagctctggagacccgggg
caggaggcgccacgggagggccgcgcccagtcctgctccccatgccgcggcccggagggt
gggcggcgagaggcaggaagccgggcgcacccgctgctgcggctcaaggcggcccacgcc
agcctctccaacgacagcctcaacagtggcagtgccagcgacgggtactgcccacgcgaa
cacatgctgccttgcccgctggccgcactggctttgcgccgcgaggaccccaggtgtggg
cagcctcggcccagccggcttgaccttgacctgccgggcagccaggccgagccgcctgcc
cgtgaagccacatccgccgacgcccgcgtgcgtaccatcaagctgtcacctacctaccag
cacgtgccactgctcgagggtgcctcaagggcgggtgcggagcccctcgcggggcctgga
acctctccaggggcccggaagcaggcctggctgccggcagaccacctgagcaaagttcct
gagaagctagcagccgccccgctgtccgtggccagcaaggcactgcagaagctggtggca
caggagggtccgctctcgttgtcccgatgcagctccctttcctcactgtcctctgccggc
cgcccaggccccagcgagggcggtgacctggatgacactgactcctctctggaggggctg
gaggaggcgggccccggcgaggctgagctggacagcgtgtggcgggcacccggggccacc
tcgctgcccgtagccattccggctccccggcgcaaccgaggccggggcctgggggtggag
gacgccacgccgtccagctcctcagagaactacgtgcaggagacaccgctggtgctgagc
cgctgcagctctgtgagctcgctgggtagctttgagagcccgtccattgccagctccatc
cccagtgacccttgcagcgggcagggcagcggcaccatcagccctagcgaactgcccgac
agccccgggcagaccatgcctcccagccggagcaagacgccgccactagcgcctgcgccg
cagggtccccccgaggccagccagttcagcctgcagtgggagagctacgtgaagcgcttc
ctggacatcgccgactgccgagagcgctgccggctgccgtctgagctggacgcaggcagc
gtgcgcttcaccgtggagaagccggatgagaacttctcgtgcgcctcgagcctcagcgcg
ctggccttgcacgagcactacgtgcagcaggacgtggagctgcggctgctgccctcggcc
tgcccagagcgcggcgggggcacagggggcgccggcctccactttgcagggcaccgacga
cgggaggaggggccagcgcccacgggttctcgcccccgcggtgccgcggaccaggagttg
gagctgctgcgggagtgcctgggggccgccgtgcctgccaggctgcgcaaggtggcctcg
gcgctggtgccaggtcgccgcgcgctccccgtgcccgtctacatgttggtgcccgcccct
gcccgggcccaggaggacgactcctgcactgactccgcggagggcacgccagtcaacttc
tccagcgccgcctccctcagcgacgagacactgcagggaccccccagggaccagcccggg
ggaccagagggcaggcaaagacccaccggccgccccacctctgccaggcaggccgtgggg
caccggcacaaggcgggaggcgccggccgcagcgtggagcaggctcggggcaccggcaag
aaccgagcagggctggagctgcccctgggccggcccccgagcgcccccgcagacaaggac
gactcgaagcccggccggacccgtggggacggggcacttcagtcgctgtgcctcacaacg
cccaccgaggaggccgtgtactgcttctatggcaacgactcggacgaggagcccccggca
gctgcgcccacgcccacccaccggcgcacatcggccatcccccgcgctcttacccgcgag
cgcctgcagggccggaaggaggcccctgccccgtccaaggccgcaccatccgccccgccg
cccacccgggcccagcccagcctcattgctgacgagaccccgccgtgctactccctgagc
tcctccgccagctccctcagcgagcccgagcccccggagccgccctccgtcagtccacga
ggccaggagcccgcggtcaccaaggacccgggcccgagaggcggacgcgacagctcgccc
agcccgcgggccgcggaggagcttctgcagcggtgcatcagctcggccctgcccaggcgc
cggccccccgtgtccggcctgcggcgccgcaagccccgagccacccggctggatgagcgg
cctgcggaggggtcccgggaacacggcgaggaggcagcgggctcggaccgggcctctgac
ctggacagcgtggagtggcgcgccatccaggagggcgccaactccatcgtcacgtggctg
caccaggcagcagctgccacgcgcgaggcctcgtccgagtccgactccatcctgtccttt
gtatccgggctgtcagtggggtctaccctacagccccccaaacacaggaagggacgacag
gcggggggcgaaatgggcagtgcccggcggccagagaaacggggcacagcctcagccaag
accagcgggagcccccgttcccctgcaggcccagagaagccacgtggcacacagaagacc
acgcccggggtgccagctgtgctccggggacgaacagtgatctatgtgcccagtccggca
cctcgtgcccagcccaaagggacccccggcccccgcgccacaccgcggaaggtggcgccc
ccttgcctggcacagtccgcagctccagccaaagtccccagccccggacagcagcggtcg
cggagcctacaccggcctggcaagacctcggagctggggacgctgagccagccccccagg
agcgctacaccgcccgcccgcctcgccaagaccccctcctccagctcctcccagacctcg
cccgcctcccagcccctgcccagaaagcgccccctggtcactcaggctgcagggcccctg
cccggccccggggcctccccagtgcccaagacgccggcgcgcactcttctggcgaagcag
cacaagacgcagaggtcgcccgtgcgtatcccgttcatgcagaagccggcccggcggggg
ccgcccccgctggctcgggcagtcccggagccgggccccaggggccgggcggggaccgag
gctggcccgggggcccgcggtggccgcctgggcctggtgcgcgtggcctcggccctctcc
agcggcagcgagtcctccgaccgctcaggcttccggcgacagctgaccttcatcaaggag
tcaccgggcttgcggcgccgccgctccgagctatcctcggccgagtctgcggcctctgcc
ccccagggcacctcgccccgccgcggccggcccgcgctgcccgccgtcttcctctgctcc
tcgcgctgcgaagagctccgagcggcaccccggcaggccccggcccggcagcggccccct
gcggcccgacccggccccggcgagcgccctgcccggcgcaccagctccgagagcccgtcc
cgcctgcccgtgcgcgcgcctgccgcccggcccgagacggtgaagcgctacgcgtcgctg
ccgcacatcagcgtggcccgcagacccgacggcgccgtcccggctgccccagccccagcc
gacgccgcgcgccgcagcagcgacggagagccccggtcgctccccagggtggctgcgccg
ggcacgacgtggcggcgcatccgggacgaggacgtgccccacatcctgcgcagcacgctg
cccgccacggccctgccactgcggggctccacgcccgaggacgccccggccgggcccccg
ccgcgcaagaccagcgacgccgtggtccagactgaggaggtcgccgcccccaagaccaac
tccagcacgtccccgagcctggagagcagggagccccccggggcccccgctagcggccag
ctctccctccttggcagcgacgtggacgggcccagcctcgccaaggctcccatctccgca
cccttcgtgcacgagggcctgggggtcgccgtggggggcttccccgccagccggcacggc
tcccccagccgctcggcccgagtaccccccttcaactatgtgcccagccccatggtggtc
gcagccaccaccgactcggccgcggagaaagccccggccacctcctccgccaccctcctg
gaatag

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein domain (17)   
   Pfam (17)   
All databases (20)   

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