KEGG   Microtus oregoni (creeping vole): 121454560
Entry
121454560         CDS       T08307                                 
Symbol
Plcb3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg00562  Inositol phosphate metabolism
morg01100  Metabolic pathways
morg04015  Rap1 signaling pathway
morg04020  Calcium signaling pathway
morg04022  cGMP-PKG signaling pathway
morg04062  Chemokine signaling pathway
morg04070  Phosphatidylinositol signaling system
morg04071  Sphingolipid signaling pathway
morg04072  Phospholipase D signaling pathway
morg04081  Hormone signaling
morg04082  Neuroactive ligand signaling
morg04261  Adrenergic signaling in cardiomyocytes
morg04270  Vascular smooth muscle contraction
morg04310  Wnt signaling pathway
morg04371  Apelin signaling pathway
morg04540  Gap junction
morg04611  Platelet activation
morg04613  Neutrophil extracellular trap formation
morg04621  NOD-like receptor signaling pathway
morg04713  Circadian entrainment
morg04720  Long-term potentiation
morg04723  Retrograde endocannabinoid signaling
morg04724  Glutamatergic synapse
morg04725  Cholinergic synapse
morg04726  Serotonergic synapse
morg04728  Dopaminergic synapse
morg04730  Long-term depression
morg04742  Taste transduction
morg04750  Inflammatory mediator regulation of TRP channels
morg04911  Insulin secretion
morg04912  GnRH signaling pathway
morg04915  Estrogen signaling pathway
morg04916  Melanogenesis
morg04918  Thyroid hormone synthesis
morg04919  Thyroid hormone signaling pathway
morg04921  Oxytocin signaling pathway
morg04922  Glucagon signaling pathway
morg04924  Renin secretion
morg04925  Aldosterone synthesis and secretion
morg04926  Relaxin signaling pathway
morg04927  Cortisol synthesis and secretion
morg04928  Parathyroid hormone synthesis, secretion and action
morg04929  GnRH secretion
morg04933  AGE-RAGE signaling pathway in diabetic complications
morg04934  Cushing syndrome
morg04935  Growth hormone synthesis, secretion and action
morg04961  Endocrine and other factor-regulated calcium reabsorption
morg04970  Salivary secretion
morg04971  Gastric acid secretion
morg04972  Pancreatic secretion
morg04973  Carbohydrate digestion and absorption
morg05010  Alzheimer disease
morg05016  Huntington disease
morg05017  Spinocerebellar ataxia
morg05022  Pathways of neurodegeneration - multiple diseases
morg05142  Chagas disease
morg05143  African trypanosomiasis
morg05146  Amoebiasis
morg05163  Human cytomegalovirus infection
morg05200  Pathways in cancer
morg05415  Diabetic cardiomyopathy
morg05417  Lipid and atherosclerosis
Module
morg_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:morg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    121454560 (Plcb3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    121454560 (Plcb3)
   04310 Wnt signaling pathway
    121454560 (Plcb3)
   04371 Apelin signaling pathway
    121454560 (Plcb3)
   04020 Calcium signaling pathway
    121454560 (Plcb3)
   04070 Phosphatidylinositol signaling system
    121454560 (Plcb3)
   04072 Phospholipase D signaling pathway
    121454560 (Plcb3)
   04071 Sphingolipid signaling pathway
    121454560 (Plcb3)
   04022 cGMP-PKG signaling pathway
    121454560 (Plcb3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    121454560 (Plcb3)
   04081 Hormone signaling
    121454560 (Plcb3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    121454560 (Plcb3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121454560 (Plcb3)
   04613 Neutrophil extracellular trap formation
    121454560 (Plcb3)
   04621 NOD-like receptor signaling pathway
    121454560 (Plcb3)
   04062 Chemokine signaling pathway
    121454560 (Plcb3)
  09152 Endocrine system
   04911 Insulin secretion
    121454560 (Plcb3)
   04922 Glucagon signaling pathway
    121454560 (Plcb3)
   04929 GnRH secretion
    121454560 (Plcb3)
   04912 GnRH signaling pathway
    121454560 (Plcb3)
   04915 Estrogen signaling pathway
    121454560 (Plcb3)
   04921 Oxytocin signaling pathway
    121454560 (Plcb3)
   04926 Relaxin signaling pathway
    121454560 (Plcb3)
   04935 Growth hormone synthesis, secretion and action
    121454560 (Plcb3)
   04918 Thyroid hormone synthesis
    121454560 (Plcb3)
   04919 Thyroid hormone signaling pathway
    121454560 (Plcb3)
   04928 Parathyroid hormone synthesis, secretion and action
    121454560 (Plcb3)
   04916 Melanogenesis
    121454560 (Plcb3)
   04924 Renin secretion
    121454560 (Plcb3)
   04925 Aldosterone synthesis and secretion
    121454560 (Plcb3)
   04927 Cortisol synthesis and secretion
    121454560 (Plcb3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121454560 (Plcb3)
   04270 Vascular smooth muscle contraction
    121454560 (Plcb3)
  09154 Digestive system
   04970 Salivary secretion
    121454560 (Plcb3)
   04971 Gastric acid secretion
    121454560 (Plcb3)
   04972 Pancreatic secretion
    121454560 (Plcb3)
   04973 Carbohydrate digestion and absorption
    121454560 (Plcb3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    121454560 (Plcb3)
  09156 Nervous system
   04724 Glutamatergic synapse
    121454560 (Plcb3)
   04725 Cholinergic synapse
    121454560 (Plcb3)
   04728 Dopaminergic synapse
    121454560 (Plcb3)
   04726 Serotonergic synapse
    121454560 (Plcb3)
   04720 Long-term potentiation
    121454560 (Plcb3)
   04730 Long-term depression
    121454560 (Plcb3)
   04723 Retrograde endocannabinoid signaling
    121454560 (Plcb3)
  09157 Sensory system
   04742 Taste transduction
    121454560 (Plcb3)
   04750 Inflammatory mediator regulation of TRP channels
    121454560 (Plcb3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    121454560 (Plcb3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121454560 (Plcb3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    121454560 (Plcb3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    121454560 (Plcb3)
   05142 Chagas disease
    121454560 (Plcb3)
   05143 African trypanosomiasis
    121454560 (Plcb3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121454560 (Plcb3)
   05016 Huntington disease
    121454560 (Plcb3)
   05017 Spinocerebellar ataxia
    121454560 (Plcb3)
   05022 Pathways of neurodegeneration - multiple diseases
    121454560 (Plcb3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121454560 (Plcb3)
   05415 Diabetic cardiomyopathy
    121454560 (Plcb3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    121454560 (Plcb3)
   04934 Cushing syndrome
    121454560 (Plcb3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:morg04131]
    121454560 (Plcb3)
Enzymes [BR:morg01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     121454560 (Plcb3)
Membrane trafficking [BR:morg04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    121454560 (Plcb3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    121454560 (Plcb3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 121454560
NCBI-ProteinID: XP_041517897
Position
Unknown
AA seq 1225 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLSPGVPLPSPQDLMGRILVKNKKRHRPSTGVPDS
SVRKRPLEQSNSALSESSATTEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGE
EGLSRGPNVLIPADREDEEEDEEEEETSDPKKPTTDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDMPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEP
FDFPKVVLPTLASLRIAAFEEGGRFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTETYQETQSQQP
GSQFLPNPTPNPLDASPRWPPGPTTSPTSTSLSSPGQRDDLIASILSEVTPTSLEELRNH
KAMVKLQSRQDRDLRELQKKHQRKTVALTRRLLDGLAQARAEGRCRPSPGAPVSKPEDIK
EYREFQNQKVQILLELREAQADAETERRLEHLRQAQQRLREVVLDAHTTQFKRLKELNER
EKKELQKILDRKRNNSISEAKTREKHKKEVELTEINRRHITESVNSIRRLEEAQKQRHER
LLAGQQQVLQQLVEEEPKLLAQLTQECREQRERLPQDTRRCLLGETSEGLGDGPQVACAS
NGHAPASGGHLSGADSESQEENTQL
NT seq 3678 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtggtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg
gtgaccctgcgtgtggatcccaatggtttcttcttgtactggacgggacccaatatggag
gtggacacgctggacatcagctccatcagggacacacggacaggtcgttatgcccgcctg
cccaaggatcccaagattcgagaagtactgggctttgggggccctgacgcccggctcgaa
gagaagctgatgacagtggtggctgggccagacccagtgaacaccacattcttgaacttc
atggccgtgcaggatgacacagtcaaggtctggtcggaggagttgttcaaactggctatg
aacatattggctcagaatgcctcccggaacaccttcctgcggaaagcatacacaaagctg
aagctgcaggtgaaccaggatggacggattccggtcaagaacattctgaagatgttctca
gcagacaagaagcgggtggagactgcgctggagtcctgtggcctcaacttcaaccggagt
gagtccatccggcctgatgagttttccctggaaatctttgagcggttcttgaacaagctg
tgtctgcgaccggatattgacaagatcctgctcgagataggtgccaagggcaagccgtac
ctcactctggagcagctcatggactttatcaaccagaagcaaagagaccccagactcaat
gaagtgctgtacccgccactgcggccctcacaggctcggttgctcattgagaagtatgag
cctaaccagcagttcctggagcgagaccaaatgtctatggagggcttcagccgctaccta
ggaggggaggagaatggcatcctgccgctggaggccctggatctgagcatggacatgacg
cagcctctgagcgcgtacttcatcaattcctcacacaatacctatctcactgcgggccag
ctggctggaacatcgtcagtggagatgtaccgccaggcgttgctgtggggctgccgctgt
gtggagctggatgtatggaagggacggccaccggaggaagagcccttcattacccatggt
tttaccatgaccactgaggtgccattgcgtgatgtgcttgaggccatcgctgagacagcc
ttcaagacctctccctaccctgtcatcctctccttcgagaaccatgtggactcggcaaaa
cagcaggccaagatggctgagtactgccgctctatctttggggatgcgctgctcattgac
cccctggataagtacccgctctctcccggagtccctctgcctagtccacaagatctgatg
ggccggatcctggtgaagaataagaagcgacatcggcccagcacaggcgtccccgacagc
tcagttcgcaagaggccgctggagcagagcaactcagccctgagcgagagctcagccact
acagagccttcctcaccccagcttgggtcacctagctcagacagctgccctggcctaagc
aatggggaggaggtgggacttgagaagaccagcctggaaccccagaagtctctaggcgag
gagggcctcagccggggacctaatgttctcatacctgctgaccgagaggatgaagaagag
gatgaagaagaggaggaaacatcggatccgaagaaacccaccacggatgagggcacagcc
agcagtgaagtcaatgccaccgaggagatgtcgacactcgtcaactacattgagcccgtc
aagttcaagtcttttgaggctgctcgaaaaaggaacaagtgcttcgagatgtcatccttt
gtggagaccaaagccatggagcaactaaccaagagtcccatggagttcgtggaatacaac
aaacagcagcttagccgcatttaccccaagggcacccgtgtggactcctccaactacatg
ccccagctcttctggaatgtgggttgccagcttgtggctctcaacttccagaccttggac
atgccaatgcagctcaacgcaggtgtcttcgaatataatgggcgcagtgggtacttgctc
aagcctgagttcatgcggcggccagacaagtcctttgaccccttcactgaggtcattgtg
gatggcatagtggccaacgccttgcgggtcaaggtgatttcggggcagttcctgtctgac
agaaaggtgggcatctacgtcgaagtggacatgtttggtctcccagttgacacaaggcgc
aaatatcgcacaaggacatcccaggggaattcattcaaccctgtgtgggatgaagagcct
tttgacttccccaaggttgtgctgcccacgctggcctcacttcgcattgcagcttttgag
gagggtggcagatttgttgggcaccgcatcctgcctgtctctgccatccgctctggatac
cactatgtctgcctgcgaaatgaggctaaccagcccctgtgtctgcctgccctgcttatc
tacactgaagcttctgactacatcccagatgaccaccaggactatgcagaggccctgatt
aaccccatcaagcatgtcagcctaatggaccagcgggccaagcagctggctgctctcatt
ggggagagcgaggctcaggccagtacagagacatatcaggagacgcagtctcaacaacca
gggtcacagttcttgcccaaccccacacctaacccactggatgcctcacctcgctggccc
ccaggtcctactacctcccccactagcacctccctcagtagcccagggcagcgagatgat
ttgattgccagcatcctctctgaggtgacccctacctctctagaggagctccgaaaccac
aaggctatggtaaagctccagagccgacaggatcgagacctgagggagctgcagaaaaag
caccagcgcaagactgtggccctcacccgccgccttctggatggtttggcgcaggccagg
gctgagggcagatgccggccctcccccggtgccccagtcagcaaacctgaagacattaag
gagtatcgagagttccagaaccaaaaggtacagatcctgctggagctgagggaggcccag
gccgatgcagaaaccgaacgaaggctggagcacctcagacaggctcagcagcggctcagg
gaggttgtcctggatgcacacacaacccagttcaagagactgaaggagctgaatgaaagg
gagaagaaggagcttcagaagatcctggacagaaaacgcaacaacagtatctcagaggcc
aagacgagagagaagcataagaaggaggtggaactgacagagattaatcggcggcatatc
actgagtcagtcaactctatcagacggctggaagaggcccagaagcagcgccatgagcgc
ctcctagcagggcagcagcaagtcctccagcagctagtggaagaggagcccaagctgctg
gcccagctgacccaggagtgtcgggagcagcgtgagaggttgccccaggacacccgtcga
tgcctgctaggcgagacatcagaggggctgggggatggcccccaggtggcttgtgccagc
aatggtcatgcacctgcgagtggtgggcacctgtccggcgctgactcggagagccaggag
gagaacacccaactctaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (11)   

Download RDF
DBGET integrated database retrieval system