KEGG   Muntiacus reevesi (Reeves' muntjac): 136175484
Entry
136175484         CDS       T10466                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01522  Endocrine resistance
mree04010  MAPK signaling pathway
mree04015  Rap1 signaling pathway
mree04068  FoxO signaling pathway
mree04071  Sphingolipid signaling pathway
mree04114  Oocyte meiosis
mree04148  Efferocytosis
mree04218  Cellular senescence
mree04261  Adrenergic signaling in cardiomyocytes
mree04370  VEGF signaling pathway
mree04380  Osteoclast differentiation
mree04517  IgSF CAM signaling
mree04519  Cadherin signaling
mree04550  Signaling pathways regulating pluripotency of stem cells
mree04611  Platelet activation
mree04613  Neutrophil extracellular trap formation
mree04620  Toll-like receptor signaling pathway
mree04621  NOD-like receptor signaling pathway
mree04622  RIG-I-like receptor signaling pathway
mree04625  C-type lectin receptor signaling pathway
mree04657  IL-17 signaling pathway
mree04658  Th1 and Th2 cell differentiation
mree04659  Th17 cell differentiation
mree04660  T cell receptor signaling pathway
mree04664  Fc epsilon RI signaling pathway
mree04668  TNF signaling pathway
mree04670  Leukocyte transendothelial migration
mree04714  Thermogenesis
mree04722  Neurotrophin signaling pathway
mree04723  Retrograde endocannabinoid signaling
mree04728  Dopaminergic synapse
mree04750  Inflammatory mediator regulation of TRP channels
mree04912  GnRH signaling pathway
mree04914  Progesterone-mediated oocyte maturation
mree04917  Prolactin signaling pathway
mree04926  Relaxin signaling pathway
mree04932  Non-alcoholic fatty liver disease
mree04933  AGE-RAGE signaling pathway in diabetic complications
mree04935  Growth hormone synthesis, secretion and action
mree04936  Alcoholic liver disease
mree05014  Amyotrophic lateral sclerosis
mree05020  Prion disease
mree05022  Pathways of neurodegeneration - multiple diseases
mree05132  Salmonella infection
mree05133  Pertussis
mree05135  Yersinia infection
mree05140  Leishmaniasis
mree05142  Chagas disease
mree05145  Toxoplasmosis
mree05152  Tuberculosis
mree05161  Hepatitis B
mree05163  Human cytomegalovirus infection
mree05167  Kaposi sarcoma-associated herpesvirus infection
mree05169  Epstein-Barr virus infection
mree05170  Human immunodeficiency virus 1 infection
mree05171  Coronavirus disease
mree05205  Proteoglycans in cancer
mree05208  Chemical carcinogenesis - reactive oxygen species
mree05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mree05415  Diabetic cardiomyopathy
mree05417  Lipid and atherosclerosis
mree05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136175484 (MAPK12)
   04015 Rap1 signaling pathway
    136175484 (MAPK12)
   04370 VEGF signaling pathway
    136175484 (MAPK12)
   04668 TNF signaling pathway
    136175484 (MAPK12)
   04068 FoxO signaling pathway
    136175484 (MAPK12)
   04071 Sphingolipid signaling pathway
    136175484 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    136175484 (MAPK12)
   04519 Cadherin signaling
    136175484 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    136175484 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    136175484 (MAPK12)
   04218 Cellular senescence
    136175484 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    136175484 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    136175484 (MAPK12)
   04613 Neutrophil extracellular trap formation
    136175484 (MAPK12)
   04620 Toll-like receptor signaling pathway
    136175484 (MAPK12)
   04621 NOD-like receptor signaling pathway
    136175484 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    136175484 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    136175484 (MAPK12)
   04660 T cell receptor signaling pathway
    136175484 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    136175484 (MAPK12)
   04659 Th17 cell differentiation
    136175484 (MAPK12)
   04657 IL-17 signaling pathway
    136175484 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    136175484 (MAPK12)
   04670 Leukocyte transendothelial migration
    136175484 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    136175484 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    136175484 (MAPK12)
   04917 Prolactin signaling pathway
    136175484 (MAPK12)
   04926 Relaxin signaling pathway
    136175484 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    136175484 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    136175484 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    136175484 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    136175484 (MAPK12)
   04722 Neurotrophin signaling pathway
    136175484 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136175484 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    136175484 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    136175484 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    136175484 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    136175484 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136175484 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    136175484 (MAPK12)
   05161 Hepatitis B
    136175484 (MAPK12)
   05171 Coronavirus disease
    136175484 (MAPK12)
   05163 Human cytomegalovirus infection
    136175484 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136175484 (MAPK12)
   05169 Epstein-Barr virus infection
    136175484 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136175484 (MAPK12)
   05135 Yersinia infection
    136175484 (MAPK12)
   05133 Pertussis
    136175484 (MAPK12)
   05152 Tuberculosis
    136175484 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    136175484 (MAPK12)
   05140 Leishmaniasis
    136175484 (MAPK12)
   05142 Chagas disease
    136175484 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    136175484 (MAPK12)
   05020 Prion disease
    136175484 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    136175484 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136175484 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    136175484 (MAPK12)
   05415 Diabetic cardiomyopathy
    136175484 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    136175484 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    136175484 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    136175484 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    136175484 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mree01001]
    136175484 (MAPK12)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     136175484 (MAPK12)
Protein kinases [BR:mree01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   136175484 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 136175484
NCBI-ProteinID: XP_065801841
Position
1:complement(62991522..62999660)
AA seq 367 aa
MSSPSPARKGFYRQEVTKTAWEVRVVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRVQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASVLTNASPLAVSLLEKMLVLDAEQRV
TAAEALAHPYFESLQDTEDEPQAQKYDESFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAK
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgtcgcccgcccgcaagggcttttatcgccaggaggtgaccaagacggcc
tgggaggtgcgcgtcgtgtaccaggatctgcaacccgtgggctcgggcgcctacggcgcc
gtgtgctcggcggtggacagccgcacgggcgccaaggttgccatcaagaagctgtaccgg
ccctttcagtccgagctgttcgccaagcgcgcctaccgcgagcttcgcctgctgaagcac
atgcgccacgagaacgtgattgggctgctggacgtgttcacgcccgacgagacgctggat
gacttcacggacttttacttggtgatgccgttcatgggcaccgacctgggaaagctcatg
aagcatgagaagctgagtgaggaccgagtgcagttccttgtctaccagatgctcaagggg
ctgaagtacatccacgctgctggcgtcatccacagggacctgaagcccggcaacctggcg
gtgaacgaggactgtgaactgaagatcctggacttcggcctggcccggcaggcagacagc
gagatgaccgggtacgtggtgacccggtggtaccgggcgcccgaggtcatcttgaactgg
atgcactacacgcagacggtggacatctggtccgtgggctgcatcatggccgagatgatc
acggggaagacgctcttcaaaggcaacgaccacctggaccagctgaaggagatcatgaag
gtgacggggacgcctcccgcggagtttgtgcagaggctgcaaagtgacgaggccaagaac
tacatgaagggcctccctgaactggagaagaaggattttgcctccgtcctgaccaacgcg
agccccctggccgtgagcctcctggagaagatgctggtgctggacgcggagcagcgggtg
acggcggccgaggcgctggcccacccctacttcgagtcgctgcaggacacggaggacgag
ccccaggcccagaaatacgatgagtccttcgatgacgtggaccgcacgctggacgagtgg
aagcgtgtcacatataaagaggtgctcagcttcaagcctccccggcagctgggggccaag
gtctccaaggagacagccttgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (11)   

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