KEGG   Myotis brandtii (Brandt's bat): 102240650
Entry
102240650         CDS       T02920                                 
Symbol
PLCB1
Name
(RefSeq) phospholipase C beta 1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
myb00562  Inositol phosphate metabolism
myb01100  Metabolic pathways
myb04015  Rap1 signaling pathway
myb04020  Calcium signaling pathway
myb04022  cGMP-PKG signaling pathway
myb04062  Chemokine signaling pathway
myb04070  Phosphatidylinositol signaling system
myb04071  Sphingolipid signaling pathway
myb04072  Phospholipase D signaling pathway
myb04081  Hormone signaling
myb04082  Neuroactive ligand signaling
myb04261  Adrenergic signaling in cardiomyocytes
myb04270  Vascular smooth muscle contraction
myb04310  Wnt signaling pathway
myb04371  Apelin signaling pathway
myb04540  Gap junction
myb04611  Platelet activation
myb04613  Neutrophil extracellular trap formation
myb04621  NOD-like receptor signaling pathway
myb04713  Circadian entrainment
myb04720  Long-term potentiation
myb04723  Retrograde endocannabinoid signaling
myb04724  Glutamatergic synapse
myb04725  Cholinergic synapse
myb04726  Serotonergic synapse
myb04728  Dopaminergic synapse
myb04730  Long-term depression
myb04742  Taste transduction
myb04750  Inflammatory mediator regulation of TRP channels
myb04911  Insulin secretion
myb04912  GnRH signaling pathway
myb04915  Estrogen signaling pathway
myb04916  Melanogenesis
myb04918  Thyroid hormone synthesis
myb04919  Thyroid hormone signaling pathway
myb04921  Oxytocin signaling pathway
myb04922  Glucagon signaling pathway
myb04924  Renin secretion
myb04925  Aldosterone synthesis and secretion
myb04926  Relaxin signaling pathway
myb04927  Cortisol synthesis and secretion
myb04928  Parathyroid hormone synthesis, secretion and action
myb04929  GnRH secretion
myb04933  AGE-RAGE signaling pathway in diabetic complications
myb04934  Cushing syndrome
myb04935  Growth hormone synthesis, secretion and action
myb04961  Endocrine and other factor-regulated calcium reabsorption
myb04970  Salivary secretion
myb04971  Gastric acid secretion
myb04972  Pancreatic secretion
myb04973  Carbohydrate digestion and absorption
myb05010  Alzheimer disease
myb05016  Huntington disease
myb05017  Spinocerebellar ataxia
myb05022  Pathways of neurodegeneration - multiple diseases
myb05142  Chagas disease
myb05143  African trypanosomiasis
myb05146  Amoebiasis
myb05163  Human cytomegalovirus infection
myb05200  Pathways in cancer
myb05415  Diabetic cardiomyopathy
myb05417  Lipid and atherosclerosis
Module
myb_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:myb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102240650 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102240650 (PLCB1)
   04310 Wnt signaling pathway
    102240650 (PLCB1)
   04371 Apelin signaling pathway
    102240650 (PLCB1)
   04020 Calcium signaling pathway
    102240650 (PLCB1)
   04070 Phosphatidylinositol signaling system
    102240650 (PLCB1)
   04072 Phospholipase D signaling pathway
    102240650 (PLCB1)
   04071 Sphingolipid signaling pathway
    102240650 (PLCB1)
   04022 cGMP-PKG signaling pathway
    102240650 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    102240650 (PLCB1)
   04081 Hormone signaling
    102240650 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102240650 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102240650 (PLCB1)
   04613 Neutrophil extracellular trap formation
    102240650 (PLCB1)
   04621 NOD-like receptor signaling pathway
    102240650 (PLCB1)
   04062 Chemokine signaling pathway
    102240650 (PLCB1)
  09152 Endocrine system
   04911 Insulin secretion
    102240650 (PLCB1)
   04922 Glucagon signaling pathway
    102240650 (PLCB1)
   04929 GnRH secretion
    102240650 (PLCB1)
   04912 GnRH signaling pathway
    102240650 (PLCB1)
   04915 Estrogen signaling pathway
    102240650 (PLCB1)
   04921 Oxytocin signaling pathway
    102240650 (PLCB1)
   04926 Relaxin signaling pathway
    102240650 (PLCB1)
   04935 Growth hormone synthesis, secretion and action
    102240650 (PLCB1)
   04918 Thyroid hormone synthesis
    102240650 (PLCB1)
   04919 Thyroid hormone signaling pathway
    102240650 (PLCB1)
   04928 Parathyroid hormone synthesis, secretion and action
    102240650 (PLCB1)
   04916 Melanogenesis
    102240650 (PLCB1)
   04924 Renin secretion
    102240650 (PLCB1)
   04925 Aldosterone synthesis and secretion
    102240650 (PLCB1)
   04927 Cortisol synthesis and secretion
    102240650 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102240650 (PLCB1)
   04270 Vascular smooth muscle contraction
    102240650 (PLCB1)
  09154 Digestive system
   04970 Salivary secretion
    102240650 (PLCB1)
   04971 Gastric acid secretion
    102240650 (PLCB1)
   04972 Pancreatic secretion
    102240650 (PLCB1)
   04973 Carbohydrate digestion and absorption
    102240650 (PLCB1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    102240650 (PLCB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    102240650 (PLCB1)
   04725 Cholinergic synapse
    102240650 (PLCB1)
   04728 Dopaminergic synapse
    102240650 (PLCB1)
   04726 Serotonergic synapse
    102240650 (PLCB1)
   04720 Long-term potentiation
    102240650 (PLCB1)
   04730 Long-term depression
    102240650 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    102240650 (PLCB1)
  09157 Sensory system
   04742 Taste transduction
    102240650 (PLCB1)
   04750 Inflammatory mediator regulation of TRP channels
    102240650 (PLCB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102240650 (PLCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102240650 (PLCB1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    102240650 (PLCB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102240650 (PLCB1)
   05142 Chagas disease
    102240650 (PLCB1)
   05143 African trypanosomiasis
    102240650 (PLCB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102240650 (PLCB1)
   05016 Huntington disease
    102240650 (PLCB1)
   05017 Spinocerebellar ataxia
    102240650 (PLCB1)
   05022 Pathways of neurodegeneration - multiple diseases
    102240650 (PLCB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102240650 (PLCB1)
   05415 Diabetic cardiomyopathy
    102240650 (PLCB1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102240650 (PLCB1)
   04934 Cushing syndrome
    102240650 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:myb04131]
    102240650 (PLCB1)
Enzymes [BR:myb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     102240650 (PLCB1)
Membrane trafficking [BR:myb04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102240650 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    102240650 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PH_14 PLCB1-4-like_EFh EF-hand_like
Other DBs
NCBI-GeneID: 102240650
NCBI-ProteinID: XP_005874802
Position
Un
AA seq 1215 aa
MHYWTFPLHDSTAVTPIILRSDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDP
KLRELLDVGNIGRLEHRMITVVYGPDLVNISYLNLVAFQEEVAKEWTNEVFNLATNLLAQ
NMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQ
EDFTPEVYRVFLNHLCPRPEIDNIFSEFGAKSRPYLTVDQMMDFINIKQRDPRLNEILYP
PLKQEQVQVLIEKYEPNTSLATKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSH
YFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTT
EISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKY
PLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSSKKKLSEQVSNTCSDSSSVFEPSSPGA
GEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNRS
FEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVAL
NFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIIS
GQFLSDKKVGTFVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLAC
LRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYA
DVIEALSNPIRYVNLMEQRAKQLAALTLEDEEDVKKEVLQGVSSPLRRTFQDTSLFSVCS
AAFGIVTWLMLCKESVGSMFQLAPVTAGGTCWVLIAIKARIILLGPGKAPAKTEDLIHSV
LTEVEAQTIEELKQQKSFVKLQKKHYKEMKELVKRHHKKTTDLIKEHTTKYNEIQNDYLR
RRAALEKTARKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQ
EQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKIT
EAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPK
LQVELEQEYQDKFKRLPLEILEFVQDAMKGKISEDSNHSSAPSSLASDAGKLNHRPPSSE
ELEGERPGKEFDTPL
NT seq 3648 nt   +upstreamnt  +downstreamnt
atgcattactggacttttcctttacacgactccactgctgtcactccaattattttgagg
tctgaccctcagggatttttcttttactggacagatcaaaacaaggagacggagctgtta
gatctcagccttgtcaaggatgccagatgtgggaaacacgccaaagctcccaaggacccc
aaattacgggaacttttggatgtggggaacatcggacgtctggaacatcgcatgataaca
gtggtgtatgggcctgacttagtgaacatctcctatttgaacctcgtggctttccaagaa
gaagtggccaaggaatggacaaatgaggttttcaatttggcaacaaacctgctggcccaa
aacatgtccagggacgcatttctggaaaaagcctatactaaacttaagctgcaagtcact
ccagaagggcgcattcctctcaaaaacatataccgcttgttttcagcagaccggaaacga
gttgaaactgctttagaggcttgtagtcttccatcatcaaggaatgattcaatacctcaa
gaagatttcactccagaagtgtacagagttttcctgaaccatctttgccctcgacctgaa
attgataacatcttttccgaatttggtgccaaaagcagaccataccttactgttgatcag
atgatggattttatcaacattaagcagcgagatcccaggctaaatgaaatactttaccca
cctttaaagcaagagcaagtccaagtattgattgagaaatatgaacccaacactagcctc
gccacaaaaggacagatctcagtggacgggtttatgcgctacctgagtggagaagaaaac
ggagtcgtttcacctgagaaactggatttgaatgaagatatgtctcagcccctttctcac
tatttcattaattcctcgcacaacacctacctcacagctggccagctggctggaaactcc
tccgtcgagatgtaccgtcaagtgctcctgtctggttgtcgctgtgtggagttggactgc
tggaaaggacggactgcagaggaggaaccagtcatcacccatgggttcaccatgacgacc
gaaatatccttcaaggaagtgatagaagcaatcgctgagtgtgcatttaagacttcacct
tttccaattctcctttcatttgagaatcatgtggactccccgaagcagcaggccaagatg
gcagagtattgtcggctgatctttggggatgcccttctcatggagcccctggaaaaatac
ccactggaatctggagttcctcttccaagccctatggacttaatgtacaaaattttggtg
aaaaataagaagaaatcacacaagtcgtcggaaggaagcagcaaaaagaaactctcagaa
caagtctcaaacacgtgcagtgactcctccagcgtgttcgagccctcgtctcccggagcc
ggggaagctgatacggagagtgacgatgacgacgatgatgatgactgtaaaaagtcttca
atggatgaggggactgctgggagcgaggccatggccacagaagagatgtctaacctggtg
aactatattcagccagtcaagtttgagtcatttgaaatttcaaaaaaaagaaacagaagt
tttgaaatgtcttccttcgtggaaaccaaaggacttgagcagctgacgaagtctccggtg
gaatttgtagaatataacaaaatgcagcttagcaggatatatccgaaaggaacacgtgta
gattcatccaactatatgcctcagctcttctggaatgcaggctgtcaaatggttgccctt
aatttccaaacagtggatctggctatgcagatcaatatggggatgtatgaatacaatggg
aagagtggctacagattaaagccagagtttatgaggcgacctgacaagcattttgatcca
ttcactgaaggcatcgtagatgggatagtggccaacactttgtctgttaagatcatttca
ggtcagtttctttctgataagaaagtcgggacttttgtggaagtggatatgtttggtttg
cctgtggacacgaggaggaaagcatttaagaccaagacatcccaaggaaatgctgtaaat
cccgtctgggaggaagaacccattgtgttcaaaaaggtagttcttccttcactcgcctgt
ctgaggatagcagcttatgaagaaggaggaaaatttattggtcatcggatcttgccagta
caagcaattcggccaggctatcactacatctgtctgaggaatgagaggaaccagcctctg
atgctgccagctgtctttgtctacatagaggtgaaagactatgttccagacacctatgca
gatgtgattgaagctttgtcaaatccaattcgatatgtgaatctgatggagcagagagct
aagcaactggctgctttgacactggaagatgaagaagacgtaaagaaagaggttctccaa
ggagtaagctctcccttgaggagaacttttcaagacaccagcctcttcagcgtatgtagt
gcagcatttgggattgtgacatggctcatgctgtgtaaagaatcagttggctccatgttc
caattggctccagttactgctggaggaacatgctgggtactaattgcaataaaagccaga
atcattttacttggccctggaaaggcacctgcaaaaacagaagatcttattcatagtgtt
ttaacagaagtggaagcgcagactattgaagagctaaagcaacagaagtcgtttgtaaaa
cttcaaaagaagcactacaaagaaatgaaagagctggttaagagacaccacaagaaaacc
acggaccttatcaaggagcacactacaaagtataatgaaattcagaatgactacctaaga
aggagagcggctttggaaaagacagccagaaaggatagtaagaaaaaatcggaacccagc
agccctgaccacggctcatcaaccattgagcaagatctggctgccctggatgccgaaatg
acccagaagttaatagacttgaaggacaagcaacaacagcaactgcttaatcttcgacaa
gaacagtattatagtgaaaaataccagaagcgagaacatattaaactgcttatccaaaaa
ttgacggatgttgctgaagaatgtcagaacaatcagttaaagaagctcaaagaaatctgt
gagaaagagaagaaggaattaaagaagaaaatggataaaaagagacaagagaagatcaca
gaagctaaatccaaagacaaaagccagatggaagaggaaaagacagagatgatccggtca
tacatccaggaggtggtgcagtacatcaagaggttagaagaggcacaaagtaaacggcaa
gaaaaactcgtagagaaacacaaggagatacgtcagcagatcctggacgaaaagcccaag
ctgcaggtggagctggagcaagagtaccaagacaagttcaaaagactgcccctggaaatt
ctggagtttgtacaggacgccatgaaagggaagatcagtgaggacagcaatcacagctct
gccccttcctccctggcctccgacgctggaaaactgaaccacaggcctccctccagtgag
gagctggaaggagagcgcccgggaaaagagtttgacactcctctgtga

  All links  
Gene (15)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (23)   

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