KEGG   Myotis davidii (David's myotis): 102751685
Entry
102751685         CDS       T02992                                 
Symbol
PLCB1
Name
(RefSeq) phospholipase C beta 1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
myd  Myotis davidii (David's myotis)
Pathway
myd00562  Inositol phosphate metabolism
myd01100  Metabolic pathways
myd04015  Rap1 signaling pathway
myd04020  Calcium signaling pathway
myd04022  cGMP-PKG signaling pathway
myd04062  Chemokine signaling pathway
myd04070  Phosphatidylinositol signaling system
myd04071  Sphingolipid signaling pathway
myd04072  Phospholipase D signaling pathway
myd04081  Hormone signaling
myd04082  Neuroactive ligand signaling
myd04261  Adrenergic signaling in cardiomyocytes
myd04270  Vascular smooth muscle contraction
myd04310  Wnt signaling pathway
myd04371  Apelin signaling pathway
myd04540  Gap junction
myd04611  Platelet activation
myd04613  Neutrophil extracellular trap formation
myd04621  NOD-like receptor signaling pathway
myd04713  Circadian entrainment
myd04720  Long-term potentiation
myd04723  Retrograde endocannabinoid signaling
myd04724  Glutamatergic synapse
myd04725  Cholinergic synapse
myd04726  Serotonergic synapse
myd04728  Dopaminergic synapse
myd04730  Long-term depression
myd04742  Taste transduction
myd04750  Inflammatory mediator regulation of TRP channels
myd04911  Insulin secretion
myd04912  GnRH signaling pathway
myd04915  Estrogen signaling pathway
myd04916  Melanogenesis
myd04918  Thyroid hormone synthesis
myd04919  Thyroid hormone signaling pathway
myd04921  Oxytocin signaling pathway
myd04922  Glucagon signaling pathway
myd04924  Renin secretion
myd04925  Aldosterone synthesis and secretion
myd04926  Relaxin signaling pathway
myd04927  Cortisol synthesis and secretion
myd04928  Parathyroid hormone synthesis, secretion and action
myd04929  GnRH secretion
myd04933  AGE-RAGE signaling pathway in diabetic complications
myd04934  Cushing syndrome
myd04935  Growth hormone synthesis, secretion and action
myd04961  Endocrine and other factor-regulated calcium reabsorption
myd04970  Salivary secretion
myd04971  Gastric acid secretion
myd04972  Pancreatic secretion
myd04973  Carbohydrate digestion and absorption
myd05010  Alzheimer disease
myd05016  Huntington disease
myd05017  Spinocerebellar ataxia
myd05022  Pathways of neurodegeneration - multiple diseases
myd05142  Chagas disease
myd05143  African trypanosomiasis
myd05146  Amoebiasis
myd05163  Human cytomegalovirus infection
myd05200  Pathways in cancer
myd05415  Diabetic cardiomyopathy
myd05417  Lipid and atherosclerosis
Module
myd_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:myd00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102751685 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102751685 (PLCB1)
   04310 Wnt signaling pathway
    102751685 (PLCB1)
   04371 Apelin signaling pathway
    102751685 (PLCB1)
   04020 Calcium signaling pathway
    102751685 (PLCB1)
   04070 Phosphatidylinositol signaling system
    102751685 (PLCB1)
   04072 Phospholipase D signaling pathway
    102751685 (PLCB1)
   04071 Sphingolipid signaling pathway
    102751685 (PLCB1)
   04022 cGMP-PKG signaling pathway
    102751685 (PLCB1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    102751685 (PLCB1)
   04081 Hormone signaling
    102751685 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102751685 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102751685 (PLCB1)
   04613 Neutrophil extracellular trap formation
    102751685 (PLCB1)
   04621 NOD-like receptor signaling pathway
    102751685 (PLCB1)
   04062 Chemokine signaling pathway
    102751685 (PLCB1)
  09152 Endocrine system
   04911 Insulin secretion
    102751685 (PLCB1)
   04922 Glucagon signaling pathway
    102751685 (PLCB1)
   04929 GnRH secretion
    102751685 (PLCB1)
   04912 GnRH signaling pathway
    102751685 (PLCB1)
   04915 Estrogen signaling pathway
    102751685 (PLCB1)
   04921 Oxytocin signaling pathway
    102751685 (PLCB1)
   04926 Relaxin signaling pathway
    102751685 (PLCB1)
   04935 Growth hormone synthesis, secretion and action
    102751685 (PLCB1)
   04918 Thyroid hormone synthesis
    102751685 (PLCB1)
   04919 Thyroid hormone signaling pathway
    102751685 (PLCB1)
   04928 Parathyroid hormone synthesis, secretion and action
    102751685 (PLCB1)
   04916 Melanogenesis
    102751685 (PLCB1)
   04924 Renin secretion
    102751685 (PLCB1)
   04925 Aldosterone synthesis and secretion
    102751685 (PLCB1)
   04927 Cortisol synthesis and secretion
    102751685 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102751685 (PLCB1)
   04270 Vascular smooth muscle contraction
    102751685 (PLCB1)
  09154 Digestive system
   04970 Salivary secretion
    102751685 (PLCB1)
   04971 Gastric acid secretion
    102751685 (PLCB1)
   04972 Pancreatic secretion
    102751685 (PLCB1)
   04973 Carbohydrate digestion and absorption
    102751685 (PLCB1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    102751685 (PLCB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    102751685 (PLCB1)
   04725 Cholinergic synapse
    102751685 (PLCB1)
   04728 Dopaminergic synapse
    102751685 (PLCB1)
   04726 Serotonergic synapse
    102751685 (PLCB1)
   04720 Long-term potentiation
    102751685 (PLCB1)
   04730 Long-term depression
    102751685 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    102751685 (PLCB1)
  09157 Sensory system
   04742 Taste transduction
    102751685 (PLCB1)
   04750 Inflammatory mediator regulation of TRP channels
    102751685 (PLCB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102751685 (PLCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102751685 (PLCB1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    102751685 (PLCB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102751685 (PLCB1)
   05142 Chagas disease
    102751685 (PLCB1)
   05143 African trypanosomiasis
    102751685 (PLCB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102751685 (PLCB1)
   05016 Huntington disease
    102751685 (PLCB1)
   05017 Spinocerebellar ataxia
    102751685 (PLCB1)
   05022 Pathways of neurodegeneration - multiple diseases
    102751685 (PLCB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102751685 (PLCB1)
   05415 Diabetic cardiomyopathy
    102751685 (PLCB1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102751685 (PLCB1)
   04934 Cushing syndrome
    102751685 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:myd04131]
    102751685 (PLCB1)
Enzymes [BR:myd01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     102751685 (PLCB1)
Membrane trafficking [BR:myd04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    102751685 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    102751685 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PLC-beta_C PI-PLC-Y PLCB1-4-like_EFh PH_14 EF-hand_like GP24_25
Other DBs
NCBI-GeneID: 102751685
NCBI-ProteinID: XP_006758144
Position
Un
AA seq 1082 aa
MITVVYGTDLVNISYLNLVAFQEEVAKEWTNEVFNLATNLLAQNMSRDAFLEKAYTKLKL
QVTPEGRIPLKNVYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNHLCP
RPEIDNIFSEFGAKSRPYLTVDQMMDFINIKQRDPRLNEILYPPLKQEQVQVLIEKYEPN
TSLATKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLA
GNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFK
TSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYK
ILVKNKKKSHKSSEGSSKKKLSEQVSNTCSDSSSVFEPSSPGAGEGLGAQGLAGEADTES
DDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNRSFEMSSFV
ETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDL
AMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDK
KVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYE
EGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYADVIEALS
NPIRYVNLMEQRAKQLAALTLEDEEEVKKEPDPGETPSEAPSEAGTTPAENGVNHTTSLA
PKPPSQALHSQPAPGSVKAPAKTEDLIHSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMK
ELVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKTAKKDSKKKSEPSSPDHGSSTIE
QDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQN
NQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIK
RLEEAQSKRQEKLVEKHKEIRQQILDEKPKGDGSSSFLSETCHEDPSVSPNFTPPNPQAL
KW
NT seq 3249 nt   +upstreamnt  +downstreamnt
atgataacagtggtgtatgggactgacttagtgaacatctcctatttgaacctcgtggct
ttccaagaagaagtggccaaggaatggacaaatgaggttttcaatttggcaacaaacctg
ctggcccaaaacatgtccagggacgcatttctggaaaaagcctatactaaacttaagctt
caagtcactccagaagggcgcattcctctcaaaaacgtataccgcttgttttcagcagac
cggaaacgagtcgaaactgctttagaggcttgtagtcttccatcatcaaggaatgattca
atacctcaagaagatttcactccagaagtatacagagttttcctgaaccatctttgccct
cgacctgaaattgataacatcttttctgaatttggtgccaaaagcagaccataccttact
gttgatcagatgatggatttcatcaacattaagcagcgagatccccggctaaatgaaata
ctttacccacctttaaagcaagagcaagtccaagtattgattgagaaatatgaacccaac
actagcctcgccacaaaaggacagatctcagtggacgggtttatgcgctacctgagtgga
gaagaaaatggagtcgtttcacctgagaaactggatttgaatgaagatatgtctcagccc
ctttctcactatttcattaattcctcgcacaacacctacctcacagctggccagctggct
ggaaactcctccgtcgagatgtaccgtcaagtgctcctgtctggttgtcgctgtgtggag
ttggactgctggaaaggacggactgcagaggaggaaccagtcatcacccatgggttcacc
atgacgaccgaaatatccttcaaggaagtgatagaagcaatcgctgagtgtgcgtttaag
acttcaccttttccaatcctgctttcatttgagaatcatgtggactccccaaagcagcag
gccaagatggcagagtattgtcggctgatcttcggggatgcccttctcatggagcccctg
gaaaaatacccactggaatctggagttcctcttccaagccctatggatttaatgtacaaa
attttggttaaaaataagaagaaatcacacaagtcgtcggaaggaagcagcaaaaagaag
ctctcagaacaagtctcaaacacgtgcagtgactcctccagcgtgttcgagccctcgtct
cccggagccggtgaggggctgggggcccaggggctggcaggggaagctgatacggagagt
gacgatgacgacgatgatgatgactgtaaaaagtcttcaatggatgaggggactgctggg
agcgaggccatggctacagaagagatgtctaacctggtgaactacattcagccagtcaag
tttgagtcatttgaaatttcaaaaaaaagaaacagaagttttgaaatgtcttccttcgtg
gaaaccaaaggacttgagcagctgacgaagtctccggtggaatttgtagaatataacaaa
atgcagcttagtagaatatatccaaaaggaacacgtgtagattcatccaactatatgcct
cagctcttctggaatgcaggctgtcaaatggttgcccttaatttccaaacagtggacctg
gctatgcagatcaatatggggatgtatgaatacaatgggaagagtggctacagattaaag
ccagagtttatgaggcgacctgacaagcattttgatccattcaccgaaggcattgtagat
gggatagtggccaacactttgtctgttaagatcatttcgggtcagtttctttctgataag
aaagttgggacttatgtggaagtggatatgttcggtttgcctgtggacacaaggaggaaa
gcatttaagaccaagacatcccaagggaatgctgtaaatcccgtctgggaggaagaaccc
attgtgttcaaaaaggtggttcttccttcactcgcctgtctgaggatagcagcttatgaa
gaaggaggaaaatttattggtcaccggatcttgccagtacaagcaattcggccaggctat
cactacatctgtctgcggaatgagaggaaccagcctctgatgctgccagctgtctttgtc
tacatagaggtgaaagactatgttccagacacctatgcagatgtgattgaagctttgtca
aatccaattcgatatgtgaatctgatggagcagagagctaagcaactggctgctttgaca
ctggaagatgaagaagaagtaaagaaagagcctgatcctggggaaacaccgtcagaagct
ccgagtgaagccgggacgactccagcagaaaatggagtaaatcacactacatccctggcg
cccaaacctccctcccaggccctccacagccaacctgctccaggttctgtaaaggcacct
gccaaaacagaagatcttattcatagtgttttaacagaagtggaagcgcagactattgaa
gagctaaagcaacagaagtcgtttgtaaaacttcaaaagaagcactacaaagaaatgaaa
gagctggttaagagacaccacaagaaaaccacggaccttatcaaggagcacactacaaag
tataatgaaattcagaatgactacctaagaaggagagcggctttggaaaagacagccaaa
aaggatagtaagaaaaaatcggaacccagcagccctgaccacggctcatcaaccattgag
caagatctggctgccctggatgccgaaatgacccagaagttaatagacttgaaggacaag
caacaacagcaactgcttaatcttcggcaagaacagtattatagtgaaaaataccagaag
cgagaacacattaaactgcttatccaaaaattgacagatgttgctgaagaatgtcagaac
aatcagttaaagaagctcaaagaaatctgtgagaaagagaagaaggaattaaagaagaaa
atggataaaaagagacaggagaagatcacagaagctaaatccaaagacaaaagccagatg
gaagaggaaaagacagagatgatccggtcatacatccaggaggtggtgcagtacatcaag
aggttggaagaggcacaaagtaaaaggcaagaaaaactcgtagagaaacacaaggagata
cgtcagcagatcctggacgaaaagcccaagggggacggttcctcctcattcttgtcggaa
acttgccatgaggatccctctgtttcccccaactttactccccccaaccctcaagctctc
aagtggtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (14)   

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