KEGG   Myotis yumanensis (Yuma myotis): 139007681
Entry
139007681         CDS       T10762                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
myum  Myotis yumanensis (Yuma myotis)
Pathway
myum01522  Endocrine resistance
myum04010  MAPK signaling pathway
myum04015  Rap1 signaling pathway
myum04068  FoxO signaling pathway
myum04071  Sphingolipid signaling pathway
myum04114  Oocyte meiosis
myum04148  Efferocytosis
myum04218  Cellular senescence
myum04261  Adrenergic signaling in cardiomyocytes
myum04370  VEGF signaling pathway
myum04380  Osteoclast differentiation
myum04517  IgSF CAM signaling
myum04519  Cadherin signaling
myum04550  Signaling pathways regulating pluripotency of stem cells
myum04611  Platelet activation
myum04613  Neutrophil extracellular trap formation
myum04620  Toll-like receptor signaling pathway
myum04621  NOD-like receptor signaling pathway
myum04622  RIG-I-like receptor signaling pathway
myum04625  C-type lectin receptor signaling pathway
myum04657  IL-17 signaling pathway
myum04658  Th1 and Th2 cell differentiation
myum04659  Th17 cell differentiation
myum04660  T cell receptor signaling pathway
myum04664  Fc epsilon RI signaling pathway
myum04668  TNF signaling pathway
myum04670  Leukocyte transendothelial migration
myum04714  Thermogenesis
myum04722  Neurotrophin signaling pathway
myum04723  Retrograde endocannabinoid signaling
myum04728  Dopaminergic synapse
myum04750  Inflammatory mediator regulation of TRP channels
myum04912  GnRH signaling pathway
myum04914  Progesterone-mediated oocyte maturation
myum04917  Prolactin signaling pathway
myum04926  Relaxin signaling pathway
myum04932  Non-alcoholic fatty liver disease
myum04933  AGE-RAGE signaling pathway in diabetic complications
myum04935  Growth hormone synthesis, secretion and action
myum04936  Alcoholic liver disease
myum05014  Amyotrophic lateral sclerosis
myum05020  Prion disease
myum05022  Pathways of neurodegeneration - multiple diseases
myum05132  Salmonella infection
myum05133  Pertussis
myum05135  Yersinia infection
myum05140  Leishmaniasis
myum05142  Chagas disease
myum05145  Toxoplasmosis
myum05152  Tuberculosis
myum05161  Hepatitis B
myum05163  Human cytomegalovirus infection
myum05167  Kaposi sarcoma-associated herpesvirus infection
myum05169  Epstein-Barr virus infection
myum05170  Human immunodeficiency virus 1 infection
myum05171  Coronavirus disease
myum05205  Proteoglycans in cancer
myum05208  Chemical carcinogenesis - reactive oxygen species
myum05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
myum05415  Diabetic cardiomyopathy
myum05417  Lipid and atherosclerosis
myum05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:myum00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    139007681 (MAPK12)
   04015 Rap1 signaling pathway
    139007681 (MAPK12)
   04370 VEGF signaling pathway
    139007681 (MAPK12)
   04668 TNF signaling pathway
    139007681 (MAPK12)
   04068 FoxO signaling pathway
    139007681 (MAPK12)
   04071 Sphingolipid signaling pathway
    139007681 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    139007681 (MAPK12)
   04519 Cadherin signaling
    139007681 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    139007681 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    139007681 (MAPK12)
   04218 Cellular senescence
    139007681 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    139007681 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    139007681 (MAPK12)
   04613 Neutrophil extracellular trap formation
    139007681 (MAPK12)
   04620 Toll-like receptor signaling pathway
    139007681 (MAPK12)
   04621 NOD-like receptor signaling pathway
    139007681 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    139007681 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    139007681 (MAPK12)
   04660 T cell receptor signaling pathway
    139007681 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    139007681 (MAPK12)
   04659 Th17 cell differentiation
    139007681 (MAPK12)
   04657 IL-17 signaling pathway
    139007681 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    139007681 (MAPK12)
   04670 Leukocyte transendothelial migration
    139007681 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    139007681 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    139007681 (MAPK12)
   04917 Prolactin signaling pathway
    139007681 (MAPK12)
   04926 Relaxin signaling pathway
    139007681 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    139007681 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    139007681 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    139007681 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    139007681 (MAPK12)
   04722 Neurotrophin signaling pathway
    139007681 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    139007681 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    139007681 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    139007681 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    139007681 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    139007681 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    139007681 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    139007681 (MAPK12)
   05161 Hepatitis B
    139007681 (MAPK12)
   05171 Coronavirus disease
    139007681 (MAPK12)
   05163 Human cytomegalovirus infection
    139007681 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    139007681 (MAPK12)
   05169 Epstein-Barr virus infection
    139007681 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    139007681 (MAPK12)
   05135 Yersinia infection
    139007681 (MAPK12)
   05133 Pertussis
    139007681 (MAPK12)
   05152 Tuberculosis
    139007681 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    139007681 (MAPK12)
   05140 Leishmaniasis
    139007681 (MAPK12)
   05142 Chagas disease
    139007681 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    139007681 (MAPK12)
   05020 Prion disease
    139007681 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    139007681 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    139007681 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    139007681 (MAPK12)
   05415 Diabetic cardiomyopathy
    139007681 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    139007681 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    139007681 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    139007681 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    139007681 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:myum01001]
    139007681 (MAPK12)
Enzymes [BR:myum01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     139007681 (MAPK12)
Protein kinases [BR:myum01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   139007681 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 139007681
NCBI-ProteinID: XP_070267441
Position
Unknown
AA seq 376 aa
MSSPPPARRGYYRQEVTKTAWEVRVVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELYAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHETLSEDRVQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEILK
VTGTPPDEFVQRLQSTDAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAAEALTHPYFESLHDAEDEPQAQKYDESFDDVDRTLDEWKLQGTRPPGEAGGGTPSPLS
LQRLSVSRRDPEQLLA
NT seq 1131 nt   +upstreamnt  +downstreamnt
atgagctccccgccgcccgcccgcaggggctactaccgccaggaggtgaccaagaccgcc
tgggaggtgcgcgtcgtgtaccaggacctgcagcccgtgggctcgggcgcctatggcgcg
gtctgctcggccgtggacagccgcacgggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtcggagctgtacgccaagcgcgcctaccgcgagctgcgcctcctcaagcac
atgcgccacgagaacgtgatcgggctgctggacgtgttcactccagatgagaccctggat
gacttcacagacttttacctggtcatgccgttcatgggcacggacctgggcaagctcatg
aagcacgagacgctgagcgaggaccgcgtccagttcctcgtctaccagatgctgaagggg
ctgaagtacatccacgcggccggtgtcattcacagggacctgaagcccggcaacctggca
gtgaacgaggactgtgagctgaagatcctggactttggcctggccaggcaggccgacagc
gagatgactggatacgtagtgacgcggtggtaccgggcgcctgaggtcatcttgaactgg
atgcactacacacagacagtggacatctggtccgtgggctgcatcatggcggagatgatc
acagggaagacgctgttcaagggcaacgaccacctggaccagctgaaggagatcttgaag
gtgacgggcacgccacccgacgagtttgtccagaggctgcagagcacggatgcgaagaac
tacatgaagggcctccccgagttggagaagaaggattttgcctccattctgaccaatgca
agccctctggcggtgaacctcctggagaaaatgctggtgctggacgcagagcagcgggtg
acggcggccgaggccctgacccacccgtacttcgagtcgctgcacgacgcggaggatgag
ccccaggcccagaagtacgacgagtcctttgacgacgtggaccgcaccctggacgagtgg
aagcttcaggggacacggccacctggtgaggctggtggagggactccatctcctttaagc
ctccagagactcagcgtgtctcggcgggaccctgagcagctgctcgcctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (7)   
   Pfam (7)   
All databases (15)   

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