KEGG   Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise): 112402798
Entry
112402798         CDS       T08872                                 
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
nasi  Neophocaena asiaeorientalis asiaeorientalis (Yangtze finless porpoise)
Pathway
nasi00562  Inositol phosphate metabolism
nasi01100  Metabolic pathways
nasi01521  EGFR tyrosine kinase inhibitor resistance
nasi01522  Endocrine resistance
nasi01524  Platinum drug resistance
nasi04012  ErbB signaling pathway
nasi04014  Ras signaling pathway
nasi04015  Rap1 signaling pathway
nasi04024  cAMP signaling pathway
nasi04062  Chemokine signaling pathway
nasi04066  HIF-1 signaling pathway
nasi04068  FoxO signaling pathway
nasi04070  Phosphatidylinositol signaling system
nasi04071  Sphingolipid signaling pathway
nasi04072  Phospholipase D signaling pathway
nasi04081  Hormone signaling
nasi04140  Autophagy - animal
nasi04145  Phagocytosis
nasi04150  mTOR signaling pathway
nasi04151  PI3K-Akt signaling pathway
nasi04152  AMPK signaling pathway
nasi04210  Apoptosis
nasi04211  Longevity regulating pathway
nasi04213  Longevity regulating pathway - multiple species
nasi04218  Cellular senescence
nasi04360  Axon guidance
nasi04370  VEGF signaling pathway
nasi04380  Osteoclast differentiation
nasi04510  Focal adhesion
nasi04517  IgSF CAM signaling
nasi04518  Integrin signaling
nasi04550  Signaling pathways regulating pluripotency of stem cells
nasi04611  Platelet activation
nasi04613  Neutrophil extracellular trap formation
nasi04620  Toll-like receptor signaling pathway
nasi04625  C-type lectin receptor signaling pathway
nasi04630  JAK-STAT signaling pathway
nasi04650  Natural killer cell mediated cytotoxicity
nasi04660  T cell receptor signaling pathway
nasi04662  B cell receptor signaling pathway
nasi04664  Fc epsilon RI signaling pathway
nasi04666  Fc gamma R-mediated phagosome formation
nasi04668  TNF signaling pathway
nasi04670  Leukocyte transendothelial migration
nasi04722  Neurotrophin signaling pathway
nasi04725  Cholinergic synapse
nasi04750  Inflammatory mediator regulation of TRP channels
nasi04810  Regulation of actin cytoskeleton
nasi04910  Insulin signaling pathway
nasi04914  Progesterone-mediated oocyte maturation
nasi04915  Estrogen signaling pathway
nasi04917  Prolactin signaling pathway
nasi04919  Thyroid hormone signaling pathway
nasi04923  Regulation of lipolysis in adipocytes
nasi04926  Relaxin signaling pathway
nasi04929  GnRH secretion
nasi04930  Type II diabetes mellitus
nasi04931  Insulin resistance
nasi04932  Non-alcoholic fatty liver disease
nasi04933  AGE-RAGE signaling pathway in diabetic complications
nasi04935  Growth hormone synthesis, secretion and action
nasi04960  Aldosterone-regulated sodium reabsorption
nasi04973  Carbohydrate digestion and absorption
nasi05010  Alzheimer disease
nasi05017  Spinocerebellar ataxia
nasi05020  Prion disease
nasi05100  Bacterial invasion of epithelial cells
nasi05132  Salmonella infection
nasi05135  Yersinia infection
nasi05142  Chagas disease
nasi05146  Amoebiasis
nasi05160  Hepatitis C
nasi05161  Hepatitis B
nasi05162  Measles
nasi05163  Human cytomegalovirus infection
nasi05164  Influenza A
nasi05165  Human papillomavirus infection
nasi05166  Human T-cell leukemia virus 1 infection
nasi05167  Kaposi sarcoma-associated herpesvirus infection
nasi05168  Herpes simplex virus 1 infection
nasi05169  Epstein-Barr virus infection
nasi05170  Human immunodeficiency virus 1 infection
nasi05171  Coronavirus disease
nasi05200  Pathways in cancer
nasi05203  Viral carcinogenesis
nasi05205  Proteoglycans in cancer
nasi05206  MicroRNAs in cancer
nasi05207  Chemical carcinogenesis - receptor activation
nasi05208  Chemical carcinogenesis - reactive oxygen species
nasi05210  Colorectal cancer
nasi05211  Renal cell carcinoma
nasi05212  Pancreatic cancer
nasi05213  Endometrial cancer
nasi05214  Glioma
nasi05215  Prostate cancer
nasi05218  Melanoma
nasi05220  Chronic myeloid leukemia
nasi05221  Acute myeloid leukemia
nasi05222  Small cell lung cancer
nasi05223  Non-small cell lung cancer
nasi05224  Breast cancer
nasi05225  Hepatocellular carcinoma
nasi05226  Gastric cancer
nasi05230  Central carbon metabolism in cancer
nasi05231  Choline metabolism in cancer
nasi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
nasi05415  Diabetic cardiomyopathy
nasi05417  Lipid and atherosclerosis
nasi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nasi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    112402798 (PIK3CD)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    112402798 (PIK3CD)
   04014 Ras signaling pathway
    112402798 (PIK3CD)
   04015 Rap1 signaling pathway
    112402798 (PIK3CD)
   04370 VEGF signaling pathway
    112402798 (PIK3CD)
   04630 JAK-STAT signaling pathway
    112402798 (PIK3CD)
   04668 TNF signaling pathway
    112402798 (PIK3CD)
   04066 HIF-1 signaling pathway
    112402798 (PIK3CD)
   04068 FoxO signaling pathway
    112402798 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    112402798 (PIK3CD)
   04072 Phospholipase D signaling pathway
    112402798 (PIK3CD)
   04071 Sphingolipid signaling pathway
    112402798 (PIK3CD)
   04024 cAMP signaling pathway
    112402798 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    112402798 (PIK3CD)
   04152 AMPK signaling pathway
    112402798 (PIK3CD)
   04150 mTOR signaling pathway
    112402798 (PIK3CD)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    112402798 (PIK3CD)
   04517 IgSF CAM signaling
    112402798 (PIK3CD)
   04518 Integrin signaling
    112402798 (PIK3CD)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    112402798 (PIK3CD)
   04140 Autophagy - animal
    112402798 (PIK3CD)
  09143 Cell growth and death
   04210 Apoptosis
    112402798 (PIK3CD)
   04218 Cellular senescence
    112402798 (PIK3CD)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112402798 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    112402798 (PIK3CD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112402798 (PIK3CD)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112402798 (PIK3CD)
   04613 Neutrophil extracellular trap formation
    112402798 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    112402798 (PIK3CD)
   04625 C-type lectin receptor signaling pathway
    112402798 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    112402798 (PIK3CD)
   04660 T cell receptor signaling pathway
    112402798 (PIK3CD)
   04662 B cell receptor signaling pathway
    112402798 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    112402798 (PIK3CD)
   04666 Fc gamma R-mediated phagosome formation
    112402798 (PIK3CD)
   04670 Leukocyte transendothelial migration
    112402798 (PIK3CD)
   04062 Chemokine signaling pathway
    112402798 (PIK3CD)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112402798 (PIK3CD)
   04923 Regulation of lipolysis in adipocytes
    112402798 (PIK3CD)
   04929 GnRH secretion
    112402798 (PIK3CD)
   04915 Estrogen signaling pathway
    112402798 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    112402798 (PIK3CD)
   04917 Prolactin signaling pathway
    112402798 (PIK3CD)
   04926 Relaxin signaling pathway
    112402798 (PIK3CD)
   04935 Growth hormone synthesis, secretion and action
    112402798 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    112402798 (PIK3CD)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    112402798 (PIK3CD)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    112402798 (PIK3CD)
  09156 Nervous system
   04725 Cholinergic synapse
    112402798 (PIK3CD)
   04722 Neurotrophin signaling pathway
    112402798 (PIK3CD)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112402798 (PIK3CD)
  09158 Development and regeneration
   04360 Axon guidance
    112402798 (PIK3CD)
   04380 Osteoclast differentiation
    112402798 (PIK3CD)
  09149 Aging
   04211 Longevity regulating pathway
    112402798 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    112402798 (PIK3CD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112402798 (PIK3CD)
   05206 MicroRNAs in cancer
    112402798 (PIK3CD)
   05205 Proteoglycans in cancer
    112402798 (PIK3CD)
   05207 Chemical carcinogenesis - receptor activation
    112402798 (PIK3CD)
   05208 Chemical carcinogenesis - reactive oxygen species
    112402798 (PIK3CD)
   05203 Viral carcinogenesis
    112402798 (PIK3CD)
   05230 Central carbon metabolism in cancer
    112402798 (PIK3CD)
   05231 Choline metabolism in cancer
    112402798 (PIK3CD)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112402798 (PIK3CD)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112402798 (PIK3CD)
   05212 Pancreatic cancer
    112402798 (PIK3CD)
   05225 Hepatocellular carcinoma
    112402798 (PIK3CD)
   05226 Gastric cancer
    112402798 (PIK3CD)
   05214 Glioma
    112402798 (PIK3CD)
   05221 Acute myeloid leukemia
    112402798 (PIK3CD)
   05220 Chronic myeloid leukemia
    112402798 (PIK3CD)
   05218 Melanoma
    112402798 (PIK3CD)
   05211 Renal cell carcinoma
    112402798 (PIK3CD)
   05215 Prostate cancer
    112402798 (PIK3CD)
   05213 Endometrial cancer
    112402798 (PIK3CD)
   05224 Breast cancer
    112402798 (PIK3CD)
   05222 Small cell lung cancer
    112402798 (PIK3CD)
   05223 Non-small cell lung cancer
    112402798 (PIK3CD)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112402798 (PIK3CD)
   05170 Human immunodeficiency virus 1 infection
    112402798 (PIK3CD)
   05161 Hepatitis B
    112402798 (PIK3CD)
   05160 Hepatitis C
    112402798 (PIK3CD)
   05171 Coronavirus disease
    112402798 (PIK3CD)
   05164 Influenza A
    112402798 (PIK3CD)
   05162 Measles
    112402798 (PIK3CD)
   05168 Herpes simplex virus 1 infection
    112402798 (PIK3CD)
   05163 Human cytomegalovirus infection
    112402798 (PIK3CD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112402798 (PIK3CD)
   05169 Epstein-Barr virus infection
    112402798 (PIK3CD)
   05165 Human papillomavirus infection
    112402798 (PIK3CD)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112402798 (PIK3CD)
   05135 Yersinia infection
    112402798 (PIK3CD)
   05100 Bacterial invasion of epithelial cells
    112402798 (PIK3CD)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    112402798 (PIK3CD)
   05142 Chagas disease
    112402798 (PIK3CD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112402798 (PIK3CD)
   05017 Spinocerebellar ataxia
    112402798 (PIK3CD)
   05020 Prion disease
    112402798 (PIK3CD)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112402798 (PIK3CD)
   05418 Fluid shear stress and atherosclerosis
    112402798 (PIK3CD)
   05415 Diabetic cardiomyopathy
    112402798 (PIK3CD)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112402798 (PIK3CD)
   04932 Non-alcoholic fatty liver disease
    112402798 (PIK3CD)
   04931 Insulin resistance
    112402798 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    112402798 (PIK3CD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112402798 (PIK3CD)
   01524 Platinum drug resistance
    112402798 (PIK3CD)
   01522 Endocrine resistance
    112402798 (PIK3CD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:nasi04131]
    112402798 (PIK3CD)
Enzymes [BR:nasi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     112402798 (PIK3CD)
Membrane trafficking [BR:nasi04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    112402798 (PIK3CD)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2 CCDC17_C
Other DBs
NCBI-GeneID: 112402798
NCBI-ProteinID: XP_024605737
UniProt: A0A341BU53
Position
Unknown
AA seq 1078 aa
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEVAAHRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSHPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSDPAPQVQKPR
AKPPPIPLKKPASVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKNQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPALDKILELGRHGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMQLCLR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDHTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKLPVEKAKPPAFGAKTSGLKLA
SYFEDGAGRGPPWLGSERRALPGEVLGRCPPGSLGAVLLGGSVTCPERVEVQGDGAPC
NT seq 3237 nt   +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagagcgtg
gccgttgatttcttgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcaccatcaagaaggtgttgtggcaccgagcccagtatgagccgctgttccac
atgctcagtgaccccgaggcctacgtgttcacctgcgtcaaccagaccgcggagcagcag
gagctggaggacgagcagcggcggctatgcgacatccagcccttcctgcccgtcctgcgc
ctggtggcccgcgagggtgaccgggtgaagaagctcatcaactcgcagatcagcttgctc
atcggcaaaggcctccacgagtttgactccttgcaagacccagaggtgaatgacttccga
gccaagatgcgccagttctgcgaggaggtggccgcgcaccggcagcagctgggctgggag
gcctggctgcagtacagcttccccctgcagctggagccctcggcgcggagctgggggccg
ggcaccctgcgcgtccccaaccgggccctgctcgtcaacgtcaagttcgagggcagcgag
gagagcttcaccttccaggtgtccaccaaggatgtgcccctggcactgatggcctgcgcg
ctccggaagaaggccacggtgttccggcagccgctggtagagcagcccgaggactacaca
ctgcaggtgaacgggaagcacgagtacctgtacggcagccaccccctctgccagttccag
tacatctgcagctgcctgcacagcgggctgaccccccacctgaccatggtgcactcctct
tccatcctcgccatgcgggacgagcagagcgaccccgccccccaagtccaaaagccacgc
gccaaaccgccccccattcctctgaagaagcccgcctcggtgtccctgtggtccctggaa
cagcctttctgcatcgagctgatccagggcagcaaagtgaatgccgatgagcggatgaag
ctggtggtgcaggccggcctcttccacggcaacgagacgctgtgcaagacggtgtccagc
tcggaggtgagcgtgtgctcagagcctgtgtggaagcagcggctggagttcgacatcaac
atctgcgatctaccgcgcatggcccgcctctgctttgcgctctacgcggtgatcgagaag
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccatcgcctgg
gccaacctcatgctgtttgattacaagaaccagctcaagaccggcgagcgctgcctctac
atgtggccctccgtcccagacgagaaaggggagctactgaacccctgtgggaccgtgcgg
agtaaccccaacactgagagcgcagccgccctggtcatctttctccctgaggtggccccc
caccctgtatactaccctgccctggacaagatcctagagctggggcggcatggggagcac
gggcgcttcacggaggaggagcagctgcagctgcgggagatcctggagcgccgggggtcc
ggggagctatacgagcacgagaaggacctggtgtggaagatgcggcacgagatccaggag
cacttccccgaggcgctggcccggttgctgctggtcaccaagtggaacaagcacgaggac
gtggcccagatgctctacctgctgtgctcctggcccgagctgcccgtcctgagcgccctg
gagctgctggacttcagcttccctgaccgccatgtgggctcctttgccatcaagtccctg
cggaaactgacggacgacgagcttttccagtacctgctgcagctggtgcaggtgctcaag
tacgagtcctacctcgactgcgagctgaccaaattcctgctggaccgggccctggccaat
cgcaagatcggccacttcctcttctggcacctgcgctccgagatgcacgtgccctcggtg
gccctgcgcttcggcctcatcatggaggcctactgcaggggcagcacccatcacatgaag
gtgctgatgaaacagggggaagcgctgagcaagctgaaagccctgaacgacgtcgtcaaa
gtgagctcccagaagaccaccaagccccagaccaaggagctgatgcagctgtgcctgcgc
caggagacctacctggaggccctctcccacctgcagtccccgctcgaccccagcaccctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
gtcatgtacagcaatgaggaggcgggcagcgatggcaccgtgggcatcatctttaagaat
ggggatgacctccgccaggacatgctgaccctgcagatgatccagctgatggacgttctg
tggaagcaggagggcttggacctgaggatgaccccttacggctgcctctccaccggggac
cacacaggcctcatcgaggtggtgcttcactcagacaccatcgccaacatccagctgaac
aagagcaacatggcggccacggctgccttcaacaaggatgctctgctcaactggctcaag
tccaagaaccctggggaggccctggatcgagccattgaggagttcaccctctcctgcgct
ggctactgcgtggccacatacgtgctgggcatcggcgatcggcacagcgacaacatcatg
atccgggagaacgggcagctgttccacattgatttcggccactttctggggaatttcaag
accaagtttggaatcaaccgtgagcgagtcccgttcatcctcacctatgactttgtgcac
gtgatccagcaggggaagacgaataatagtgagaaatttgaaaggttccggggctactgt
gaaagggcctacaccatcctgcggcgccacgggctgctctttctccacctctttgctctc
atgcgggcggcaggcctgcccgagctcagctgctccaaagacatccagtacctcaagctt
ccagtggagaaggccaagccgcctgccttcggggccaagacctccgggctcaagttggca
tcttattttgaggatggggcggggcgggggccgccttggttggggtcggaacgaagagct
cttccgggggaggtgctgggtaggtgccctcctggctcccttggtgcagttctcttagga
gggagcgttacctgcccagagagggtggaggtgcagggagacggggctccctgctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (8)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (6)   
   Pfam (6)   
All databases (25)   

Download RDF
DBGET integrated database retrieval system