KEGG   Sciurus carolinensis (gray squirrel): 124979014
Entry
124979014         CDS       T08117                                 
Name
(RefSeq) protein kinase C alpha type isoform X1
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
ncar  Sciurus carolinensis (gray squirrel)
Pathway
ncar01521  EGFR tyrosine kinase inhibitor resistance
ncar04010  MAPK signaling pathway
ncar04012  ErbB signaling pathway
ncar04014  Ras signaling pathway
ncar04015  Rap1 signaling pathway
ncar04020  Calcium signaling pathway
ncar04066  HIF-1 signaling pathway
ncar04070  Phosphatidylinositol signaling system
ncar04071  Sphingolipid signaling pathway
ncar04072  Phospholipase D signaling pathway
ncar04082  Neuroactive ligand signaling
ncar04150  mTOR signaling pathway
ncar04151  PI3K-Akt signaling pathway
ncar04261  Adrenergic signaling in cardiomyocytes
ncar04270  Vascular smooth muscle contraction
ncar04310  Wnt signaling pathway
ncar04360  Axon guidance
ncar04370  VEGF signaling pathway
ncar04510  Focal adhesion
ncar04517  IgSF CAM signaling
ncar04540  Gap junction
ncar04613  Neutrophil extracellular trap formation
ncar04650  Natural killer cell mediated cytotoxicity
ncar04664  Fc epsilon RI signaling pathway
ncar04666  Fc gamma R-mediated phagosome formation
ncar04670  Leukocyte transendothelial migration
ncar04713  Circadian entrainment
ncar04720  Long-term potentiation
ncar04723  Retrograde endocannabinoid signaling
ncar04724  Glutamatergic synapse
ncar04725  Cholinergic synapse
ncar04726  Serotonergic synapse
ncar04727  GABAergic synapse
ncar04728  Dopaminergic synapse
ncar04730  Long-term depression
ncar04750  Inflammatory mediator regulation of TRP channels
ncar04911  Insulin secretion
ncar04912  GnRH signaling pathway
ncar04916  Melanogenesis
ncar04918  Thyroid hormone synthesis
ncar04919  Thyroid hormone signaling pathway
ncar04921  Oxytocin signaling pathway
ncar04925  Aldosterone synthesis and secretion
ncar04926  Relaxin signaling pathway
ncar04928  Parathyroid hormone synthesis, secretion and action
ncar04929  GnRH secretion
ncar04933  AGE-RAGE signaling pathway in diabetic complications
ncar04935  Growth hormone synthesis, secretion and action
ncar04960  Aldosterone-regulated sodium reabsorption
ncar04961  Endocrine and other factor-regulated calcium reabsorption
ncar04970  Salivary secretion
ncar04971  Gastric acid secretion
ncar04972  Pancreatic secretion
ncar05017  Spinocerebellar ataxia
ncar05022  Pathways of neurodegeneration - multiple diseases
ncar05031  Amphetamine addiction
ncar05032  Morphine addiction
ncar05143  African trypanosomiasis
ncar05146  Amoebiasis
ncar05161  Hepatitis B
ncar05163  Human cytomegalovirus infection
ncar05164  Influenza A
ncar05170  Human immunodeficiency virus 1 infection
ncar05171  Coronavirus disease
ncar05200  Pathways in cancer
ncar05205  Proteoglycans in cancer
ncar05206  MicroRNAs in cancer
ncar05207  Chemical carcinogenesis - receptor activation
ncar05214  Glioma
ncar05223  Non-small cell lung cancer
ncar05225  Hepatocellular carcinoma
ncar05231  Choline metabolism in cancer
ncar05415  Diabetic cardiomyopathy
ncar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ncar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    124979014
   04012 ErbB signaling pathway
    124979014
   04014 Ras signaling pathway
    124979014
   04015 Rap1 signaling pathway
    124979014
   04310 Wnt signaling pathway
    124979014
   04370 VEGF signaling pathway
    124979014
   04066 HIF-1 signaling pathway
    124979014
   04020 Calcium signaling pathway
    124979014
   04070 Phosphatidylinositol signaling system
    124979014
   04072 Phospholipase D signaling pathway
    124979014
   04071 Sphingolipid signaling pathway
    124979014
   04151 PI3K-Akt signaling pathway
    124979014
   04150 mTOR signaling pathway
    124979014
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    124979014
   04517 IgSF CAM signaling
    124979014
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    124979014
   04540 Gap junction
    124979014
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    124979014
   04650 Natural killer cell mediated cytotoxicity
    124979014
   04664 Fc epsilon RI signaling pathway
    124979014
   04666 Fc gamma R-mediated phagosome formation
    124979014
   04670 Leukocyte transendothelial migration
    124979014
  09152 Endocrine system
   04911 Insulin secretion
    124979014
   04929 GnRH secretion
    124979014
   04912 GnRH signaling pathway
    124979014
   04921 Oxytocin signaling pathway
    124979014
   04926 Relaxin signaling pathway
    124979014
   04935 Growth hormone synthesis, secretion and action
    124979014
   04918 Thyroid hormone synthesis
    124979014
   04919 Thyroid hormone signaling pathway
    124979014
   04928 Parathyroid hormone synthesis, secretion and action
    124979014
   04916 Melanogenesis
    124979014
   04925 Aldosterone synthesis and secretion
    124979014
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    124979014
   04270 Vascular smooth muscle contraction
    124979014
  09154 Digestive system
   04970 Salivary secretion
    124979014
   04971 Gastric acid secretion
    124979014
   04972 Pancreatic secretion
    124979014
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    124979014
   04961 Endocrine and other factor-regulated calcium reabsorption
    124979014
  09156 Nervous system
   04724 Glutamatergic synapse
    124979014
   04727 GABAergic synapse
    124979014
   04725 Cholinergic synapse
    124979014
   04728 Dopaminergic synapse
    124979014
   04726 Serotonergic synapse
    124979014
   04720 Long-term potentiation
    124979014
   04730 Long-term depression
    124979014
   04723 Retrograde endocannabinoid signaling
    124979014
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    124979014
  09158 Development and regeneration
   04360 Axon guidance
    124979014
  09159 Environmental adaptation
   04713 Circadian entrainment
    124979014
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    124979014
   05206 MicroRNAs in cancer
    124979014
   05205 Proteoglycans in cancer
    124979014
   05207 Chemical carcinogenesis - receptor activation
    124979014
   05231 Choline metabolism in cancer
    124979014
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    124979014
   05214 Glioma
    124979014
   05223 Non-small cell lung cancer
    124979014
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    124979014
   05161 Hepatitis B
    124979014
   05171 Coronavirus disease
    124979014
   05164 Influenza A
    124979014
   05163 Human cytomegalovirus infection
    124979014
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    124979014
   05143 African trypanosomiasis
    124979014
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    124979014
   05022 Pathways of neurodegeneration - multiple diseases
    124979014
  09165 Substance dependence
   05031 Amphetamine addiction
    124979014
   05032 Morphine addiction
    124979014
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    124979014
   05415 Diabetic cardiomyopathy
    124979014
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    124979014
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    124979014
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ncar01001]
    124979014
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ncar04131]
    124979014
Enzymes [BR:ncar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     124979014
Protein kinases [BR:ncar01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   124979014
Membrane trafficking [BR:ncar04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    124979014
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2
Other DBs
NCBI-GeneID: 124979014
NCBI-ProteinID: XP_047399026
Position
3:12579716..12983224
AA seq 688 aa
MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI
DWEKLENREIQPPFKPKVTFCTKMHWLQWASRPSCGKGAENFDKFFTRGQPVLTPPDQLV
IANIDQSDFEGFSYVNPQFVHPILQSAV
NT seq 2067 nt   +upstreamnt  +downstreamnt
atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgagacagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggattccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa
tttgttactttctcatgcccgggtgcagacaagggacccgacactgatgaccccaggagc
aagcacaagttcaaaatccacacttatgggagcccgaccttctgtgatcactgtgggtcc
ctgctgtacggacttatccaccaagggatgaaatgtgacacctgcgacatgaatgttcac
aagcagtgtgtgatcaacgtccccagcctctgcggaatggatcacacagagaagagaggg
cggatttacctgaaggcagaggtcaccgatgaaaagctccatgtcacagtacgagatgca
aaaaatctcatccctatggatcccaatgggctttccgatccttatgtgaagctgaaactt
attcctgaccccaagaatgaaagcaaacagaaaaccaaaaccatccgttccacactgaac
ccccagtggaatgagtccttcaccttcaaactaaaaccttcagacaaagaccgacggctg
tctgtagaaatctgggactgggatcggacaacaaggaatgacttcatgggatccctttcc
ttcggagtctcggagctaatgaagatgccggccagtggatggtacaagttgctgaaccag
gaagaaggcgagtactacaacgtgcccattccagaaggggacgaggaagggaacgtggag
ctcaggcagaaattcgagaaagccaagctcggccctgcgggtaacaaggtgatcagtcct
tctgaagaccggaaacaaccttccaacaaccttgacagagtgaaactcaccgacttcaat
ttcctcatggtgctggggaaggggagttttgggaaggtgatgcttgctgacaggaaggga
acagaagaactgtacgccatcaaaatcctgaagaaggacgtggtgattcaggacgacgat
gtggagtgcaccatggtggagaagcgggtcctggccctgcttgacaagcccccgttcctg
acgcagctgcactcctgcttccagaccgtggatcggctgtactttgtcatggagtatgtc
aacggcggggacctcatgtaccacattcagcaagtaggaaagtttaaggagccacaagca
gtattctatgcagcagagatttccattggattgttctttcttcataaaagaggaatcatt
tatagggacctgaagttagataatgtcatgctggactcagaaggacacatcaaaatcgct
gactttgggatgtgcaaagaacacatgatggacggagtcacgaccaggaccttctgtggg
actccagattacatcgcccctgagattatcgcttaccagccgtatggaaagtcggtggac
tggtgggcctatggtgtgctgctgtacgaaatgctagctggccagcctccatttgacggt
gaggatgaagatgagctgttccagtctataatggagcacaacgtctcctatcccaagtcc
ttgtccaaagaggccgtctctatctgcaaagggctgatgaccaagcacccagccaagcgg
ctgggctgtgggcccgagggagagagggacgtgagagaacacgccttcttccggaggatc
gactgggaaaagctggagaacagggagatccagccgcccttcaagcccaaagtgactttc
tgtaccaaaatgcactggcttcagtgggcatccaggccttcgtgtggcaaaggagcagaa
aactttgacaagttcttcacacgagggcaacctgtcttaacaccaccagatcagttggtc
atcgctaacatagaccagtctgattttgaagggttctcatacgtcaacccccagtttgtg
cacccaatcttgcagagtgcggtatga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (13)   

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