KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103739660
Entry
103739660         CDS       T03372                                 
Symbol
Mapk14
Name
(RefSeq) mitogen-activated protein kinase 14
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01522  Endocrine resistance
ngi04010  MAPK signaling pathway
ngi04015  Rap1 signaling pathway
ngi04068  FoxO signaling pathway
ngi04071  Sphingolipid signaling pathway
ngi04114  Oocyte meiosis
ngi04148  Efferocytosis
ngi04218  Cellular senescence
ngi04261  Adrenergic signaling in cardiomyocytes
ngi04370  VEGF signaling pathway
ngi04380  Osteoclast differentiation
ngi04517  IgSF CAM signaling
ngi04519  Cadherin signaling
ngi04550  Signaling pathways regulating pluripotency of stem cells
ngi04611  Platelet activation
ngi04613  Neutrophil extracellular trap formation
ngi04620  Toll-like receptor signaling pathway
ngi04621  NOD-like receptor signaling pathway
ngi04622  RIG-I-like receptor signaling pathway
ngi04625  C-type lectin receptor signaling pathway
ngi04657  IL-17 signaling pathway
ngi04658  Th1 and Th2 cell differentiation
ngi04659  Th17 cell differentiation
ngi04660  T cell receptor signaling pathway
ngi04664  Fc epsilon RI signaling pathway
ngi04668  TNF signaling pathway
ngi04670  Leukocyte transendothelial migration
ngi04714  Thermogenesis
ngi04722  Neurotrophin signaling pathway
ngi04723  Retrograde endocannabinoid signaling
ngi04728  Dopaminergic synapse
ngi04750  Inflammatory mediator regulation of TRP channels
ngi04912  GnRH signaling pathway
ngi04914  Progesterone-mediated oocyte maturation
ngi04917  Prolactin signaling pathway
ngi04926  Relaxin signaling pathway
ngi04932  Non-alcoholic fatty liver disease
ngi04933  AGE-RAGE signaling pathway in diabetic complications
ngi04935  Growth hormone synthesis, secretion and action
ngi04936  Alcoholic liver disease
ngi05014  Amyotrophic lateral sclerosis
ngi05020  Prion disease
ngi05022  Pathways of neurodegeneration - multiple diseases
ngi05132  Salmonella infection
ngi05133  Pertussis
ngi05135  Yersinia infection
ngi05140  Leishmaniasis
ngi05142  Chagas disease
ngi05145  Toxoplasmosis
ngi05152  Tuberculosis
ngi05161  Hepatitis B
ngi05163  Human cytomegalovirus infection
ngi05167  Kaposi sarcoma-associated herpesvirus infection
ngi05169  Epstein-Barr virus infection
ngi05170  Human immunodeficiency virus 1 infection
ngi05171  Coronavirus disease
ngi05205  Proteoglycans in cancer
ngi05208  Chemical carcinogenesis - reactive oxygen species
ngi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ngi05415  Diabetic cardiomyopathy
ngi05417  Lipid and atherosclerosis
ngi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103739660 (Mapk14)
   04015 Rap1 signaling pathway
    103739660 (Mapk14)
   04370 VEGF signaling pathway
    103739660 (Mapk14)
   04668 TNF signaling pathway
    103739660 (Mapk14)
   04068 FoxO signaling pathway
    103739660 (Mapk14)
   04071 Sphingolipid signaling pathway
    103739660 (Mapk14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    103739660 (Mapk14)
   04519 Cadherin signaling
    103739660 (Mapk14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103739660 (Mapk14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103739660 (Mapk14)
   04218 Cellular senescence
    103739660 (Mapk14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103739660 (Mapk14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103739660 (Mapk14)
   04613 Neutrophil extracellular trap formation
    103739660 (Mapk14)
   04620 Toll-like receptor signaling pathway
    103739660 (Mapk14)
   04621 NOD-like receptor signaling pathway
    103739660 (Mapk14)
   04622 RIG-I-like receptor signaling pathway
    103739660 (Mapk14)
   04625 C-type lectin receptor signaling pathway
    103739660 (Mapk14)
   04660 T cell receptor signaling pathway
    103739660 (Mapk14)
   04658 Th1 and Th2 cell differentiation
    103739660 (Mapk14)
   04659 Th17 cell differentiation
    103739660 (Mapk14)
   04657 IL-17 signaling pathway
    103739660 (Mapk14)
   04664 Fc epsilon RI signaling pathway
    103739660 (Mapk14)
   04670 Leukocyte transendothelial migration
    103739660 (Mapk14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103739660 (Mapk14)
   04914 Progesterone-mediated oocyte maturation
    103739660 (Mapk14)
   04917 Prolactin signaling pathway
    103739660 (Mapk14)
   04926 Relaxin signaling pathway
    103739660 (Mapk14)
   04935 Growth hormone synthesis, secretion and action
    103739660 (Mapk14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103739660 (Mapk14)
  09156 Nervous system
   04728 Dopaminergic synapse
    103739660 (Mapk14)
   04723 Retrograde endocannabinoid signaling
    103739660 (Mapk14)
   04722 Neurotrophin signaling pathway
    103739660 (Mapk14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103739660 (Mapk14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103739660 (Mapk14)
  09159 Environmental adaptation
   04714 Thermogenesis
    103739660 (Mapk14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103739660 (Mapk14)
   05208 Chemical carcinogenesis - reactive oxygen species
    103739660 (Mapk14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103739660 (Mapk14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103739660 (Mapk14)
   05161 Hepatitis B
    103739660 (Mapk14)
   05171 Coronavirus disease
    103739660 (Mapk14)
   05163 Human cytomegalovirus infection
    103739660 (Mapk14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103739660 (Mapk14)
   05169 Epstein-Barr virus infection
    103739660 (Mapk14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103739660 (Mapk14)
   05135 Yersinia infection
    103739660 (Mapk14)
   05133 Pertussis
    103739660 (Mapk14)
   05152 Tuberculosis
    103739660 (Mapk14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103739660 (Mapk14)
   05140 Leishmaniasis
    103739660 (Mapk14)
   05142 Chagas disease
    103739660 (Mapk14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103739660 (Mapk14)
   05020 Prion disease
    103739660 (Mapk14)
   05022 Pathways of neurodegeneration - multiple diseases
    103739660 (Mapk14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103739660 (Mapk14)
   05418 Fluid shear stress and atherosclerosis
    103739660 (Mapk14)
   05415 Diabetic cardiomyopathy
    103739660 (Mapk14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103739660 (Mapk14)
   04932 Non-alcoholic fatty liver disease
    103739660 (Mapk14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103739660 (Mapk14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103739660 (Mapk14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ngi01001]
    103739660 (Mapk14)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103739660 (Mapk14)
Protein kinases [BR:ngi01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103739660 (Mapk14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 103739660
NCBI-ProteinID: XP_008838308
UniProt: A0A8C6QP58
Position
Un
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtcccaggagaggcccacgttctaccggcaggagctgaacaagaccatctgggaggtg
ccggagcgctatcagaacctgtccccggtgggctcgggcgcctatggctcggtgtgcgct
gcttttgatacaaaaacgggcctgcgtgtggcggtgaagaagctgtcccggccatttcag
tccatcattcacgccaaacggacctaccgggagctgcggctgctgaaacacatgaaacat
gagaacgtgattggtctactggatgtttttacacctgcaaggtccctggaggagttcaat
gacgtgtacctggtgacccatctcatgggggcagatctgaacaacatcgtgaagtgtcag
aagctcactgatgaccacgtacagttcctcatttaccagatcctccgaggcctaaagtac
atacactcagctgacataatccacagggacctaaagcccagtaacctcgccgtgaacgaa
gactgtgagctgaagattctggactttggactggctcggcacactgatgacgagatgact
ggctacgtggccaccaggtggtacagagctcctgagatcatgctgaactggatgcattac
aaccagacagtggatatctggtccgtggggtgcatcatggctgagctgttgaccggaaga
acactattccctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactatatccag
tctttggcccagatgcctaagatgaactttgcaaacgtatttattggtgccaatcccctg
gctgtcgaccttctggagaagatgcttgtattggactcagataagaggatcacagcagcc
caagcccttgctcatgcctactttgctcaataccacgaccctgatgatgagcctgtggcc
gacccttatgaccagtcctttgaaagcagggacctccttatagacgagtggaaaagcctg
acctatgatgaagtcatcagctttgtgccaccgccccttgaccaagaagagatggagtct
tga

  All links  
Gene (5)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (7)   
   RefSeq(nuc) (3)   
   GenBank (2)   
   EMBL (2)   
Protein domain (6)   
   Pfam (6)   
All databases (22)   

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