KEGG   Naegleria gruberi: NAEGRDRAFT_81057
Entry
NAEGRDRAFT_81057  CDS       T01241                                 
Name
(RefSeq) hypothetical protein
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
ngr  Naegleria gruberi
Pathway
ngr00562  Inositol phosphate metabolism
ngr01100  Metabolic pathways
ngr04070  Phosphatidylinositol signaling system
ngr04081  Hormone signaling
ngr04145  Phagocytosis
ngr04517  IgSF CAM signaling
ngr04518  Integrin signaling
ngr04620  Toll-like receptor signaling pathway
ngr05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:ngr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    NAEGRDRAFT_81057
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    NAEGRDRAFT_81057
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    NAEGRDRAFT_81057
   04517 IgSF CAM signaling
    NAEGRDRAFT_81057
   04518 Integrin signaling
    NAEGRDRAFT_81057
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    NAEGRDRAFT_81057
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    NAEGRDRAFT_81057
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    NAEGRDRAFT_81057
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ngr04131]
    NAEGRDRAFT_81057
Enzymes [BR:ngr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     NAEGRDRAFT_81057
Membrane trafficking [BR:ngr04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    NAEGRDRAFT_81057
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_C2 PI3K_rbd
Other DBs
NCBI-GeneID: 8854754
NCBI-ProteinID: XP_002673067
JGI: Naegr1_81057
UniProt: D2VSC9
AA seq 1299 aa
MRFFNRGGKKDDKNKNNGSTTTTPDNSSGTTTTNGGRSGSTTQTPPISTGIQDSTVSGSP
TSMTPTSTVGSGSSSSNGGENSPATVAVVEGSGVNVKSLITKTLTSLQEIWDIHGEFLTV
TADEEDTKQKLSKLTKSEIRKHIDLLIGKREEWSSESDEAFAYRYNIRKAHVMSENKSIE
RGDLLPPVYLTSDTTFDPSIKFFCKVNLVGDNFQRMVDCEPYSSADDFAELFINKINKSH
LLNRRKEDWIFKATGTSEYIYGNQRMIDFEVIRRCLKRGINRVQLNLMDKETVLKELDPY
DMNLRTTEYDFDFKRTPRYSMDDHERFKKIQKDIRGNKKHIFLHYNRFKGVQTYSSYTED
EFSKNSSSTILDDDEWISKIDQTDNNHNLTQANLTMRDSLFRTEELIRDKKAFTLWDIHR
PFRLKIVGLDNIPLSEDRAIYITAQVFLGGMPLTNCRITKCVIQNRNPRFNQYITFPELY
ISELPREAKICITAFSKPYVQNDPHLIVSNRSPTIQDMTKLASSTIKKGVITGNETLQIN
TANTQLQLGTSPSMISNPTEIIDIDQSSAASSSFLNGDEEDILEHEQEQGEGGKKSKKDK
TNVPVAGMNFQLFNFCGTLKQGVYCLKVEPNREAKPIMTSGESKDSKISMTFSLDEYLLP
IVYPDDEDSFSSIVTTDQTNTSFSDTLNSLKQTKDQLTRSLSTTEGGMSFNPLTQPRKTQ
IQNTGEQSKPVAPNRFKKHLPEIFIKRFEEYVAKKNSESLPPGIAEKKLEKVLNYDPLKT
LNSEERWLCFLNRDKLIAKPKALSKFLLSVPWKFPEARLIAKEYLAKWNAIEPIDALELL
DHNFGASFIREYSIGRLNQLSDQQLCNYLLQLVQTLKYESYHDSSLARFLLQRGLRSPNI
IGHILFWHLKAEMYVPSIRERHGLILEEYLRNCGSHRIALLQQTGVLHQLNVIAEGVKII
DKEECKEYVKTCLAELKHPPKFKLPLSPRMEVKGIEVDRCRVMSSKKKPLWLVFQNADAT
GDPIQVMFKAGDDLRQDLLTLQILSIMDQLWKKKGLDLHMNPYGCICTGDQQGFIEIVVD
SDTVANITAGDTGGISGGIKAFTSAPLEIWLLKNNGGVITSPDYEKAVQNFALSCAGYCA
ATYVLGIGDRHNDNIMLTRKGDLFHIDFGHFLGNFKSYKGIYKRETTPFVFTPMYAQVMK
SFDSENKGKCYYSTFEEKVIAAYQILRENGHLIMNLFLLMLATGIPELTSVSDIKWLRDC
LVLDKSPEEAEQHFRDKITKALANTKSQFNDFVHIVKHK
NT seq 3900 nt   +upstreamnt  +downstreamnt
atgaggttctttaatcgtggtggaaagaaggacgataaaaacaagaacaacggttctaca
accacaacaccagataatagcagtggtaccactactacaaatggaggtcgttctggttct
accactcaaacacctccaatttcaactggaatacaagattcaacagtgagtggtagtcct
acttcaatgactccaacctccactgttggttctggttcttcttcttcaaatggtggagaa
aattcaccagctacagtagcagtagtagaaggctctggtgtcaatgtaaaatcactcatc
accaagaccttgacctctctacaggaaatttgggatattcacggagagtttttgactgta
acagcagatgaagaagatactaaacaaaaactttcaaaattgacaaaatcagaaattaga
aaacacattgatttattaattggtaagagagaagagtggagttctgagagtgatgaagct
tttgcctatcgatacaatattagaaaggctcacgttatgagtgaaaacaaatctatagaa
agaggtgatttacttccacctgtttatttaacctctgatactacttttgatccgagtatt
aaattcttttgtaaagtaaatttagttggagacaatttccaaagaatggttgattgtgaa
ccatattcctctgctgacgattttgccgagttgtttattaacaagattaacaagtcacat
ctcttgaatagaagaaaggaagactggatttttaaagctactggtacatctgaatatatt
tatggtaatcaaagaatgattgattttgaagtgattagaagatgtttgaaacgtggtatt
aatcgtgtccaactaaacctcatggacaaggaaactgtcttgaaagaattggatccatat
gatatgaatttgaggacaactgaatatgattttgattttaagagaactccaagatattcc
atggatgatcatgaaagattcaaaaagattcaaaaagatattagaggaaacaagaagcac
atctttttgcattacaatagattcaaaggagtgcaaacatatagtagttatacagaagat
gaattttctaaaaacagctcttcaacaattttggatgacgatgaatggattagtaagatt
gatcaaactgataataatcacaatttgacacaagcaaatctcacaatgagagattcttta
ttcaggactgaagaattaattagagataagaaggcattcacattgtgggatattcatcgt
ccattccgtcttaaaattgttggacttgataatattccactctcagaagatagagctatt
tacattactgctcaagtttttttaggtggaatgccgttgacaaattgtcgtattacaaag
tgtgtaatccaaaatagaaatccacgctttaatcaatatattaccttccctgaattgtac
atttctgaactccctcgagaagctaaaatttgcattacagcttttagcaaaccatacgtc
caaaatgatccacacttaattgtatcaaatagatcaccaaccattcaagatatgacaaaa
cttgctagtagtaccatcaagaagggtgttattactggtaatgaaacactccaaattaat
acagcaaatactcaacttcaactaggaacatctccatcaatgatttcaaatccaactgaa
attattgatattgatcaatcttcagctgcttcttccagtttcttgaacggagatgaagaa
gatattctcgaacatgaacaagaacaaggagaaggtggtaaaaaatccaagaaggataag
acaaatgttcctgtagctggtatgaatttccaattattcaacttttgtggaactctcaaa
caaggtgtttattgtctcaaagtggaaccaaatagagaagccaaaccaatcatgacaagt
ggtgaatctaaggatagcaagatttcaatgactttcagtttggacgaatatctgttacct
attgtttatcctgatgatgaagatagtttctcttctatagtcactacagatcaaactaat
acttctttctctgacactctcaacagtcttaaacaaacaaaggaccaattgacaagatca
ctttcaacaactgaaggtggaatgtcattcaatcctcttactcaaccaagaaaaactcaa
attcaaaacacaggagaacaatcaaaaccagttgctccaaatagattcaagaagcattta
ccagaaatatttatcaagagatttgaagaatatgttgccaagaagaatagtgaaagttta
cctccaggtattgctgaaaagaaattagaaaaagttttgaattatgatccactcaagaca
ctcaactctgaagaacgttggttgtgtttcctcaatagagacaaacttattgccaaacca
aaggctctctccaagttcttgctttctgtaccttggaagttccctgaagcaagattgatt
gccaaggaatatttggccaagtggaatgctattgaaccaatagatgcattggaattgttg
gatcacaactttggagccagttttattagagaatattcgataggacgacttaaccaactc
tcagatcaacaactttgtaactatcttcttcaattggttcaaaccttgaaatatgaaagt
tatcatgactcttcacttgctagattcttactccaacgtggtttgagatcaccaaatatt
attggtcacattctcttttggcatttgaaggcagaaatgtatgtaccatctattagagaa
agacacggtttgattttggaagaatatttgagaaattgtggctctcaccgtatcgccctg
ttgcaacaaacaggtgtacttcatcaattgaatgtaattgctgagggtgttaaaataata
gataaggaagaatgtaaagaatatgttaagacatgtttagcagaacttaaacatccacca
aaattcaaattgccactctcacctcgtatggaagttaagggaattgaagttgatagatgt
cgtgtcatgagcagtaagaagaaacctctttggttggtattccaaaatgcagatgcaact
ggtgacccaattcaagtcatgttcaaggcaggtgacgatctgagacaggatttgctgaca
cttcaaattctttctattatggatcaattgtggaagaagaaaggtctggatcttcacatg
aacccatatggttgtatttgtacaggagatcaacaaggttttattgaaattgtcgttgac
agtgacactgttgctaatattactgctggtgatacaggaggtatttcaggaggtattaag
gcttttacaagtgcacctcttgaaatttggttgttaaagaataatggtggagttattact
tcaccagattatgagaaagctgtacaaaactttgcattatcatgtgctggatactgtgct
gccacatatgttttaggtattggtgatagacacaatgataatattatgttaactagaaaa
ggtgatttattccacattgactttggtcacttccttggtaactttaaatcctataagggt
atttataagagagaaactacaccattcgtttttactccaatgtatgcccaagttatgaaa
tcttttgattctgaaaataagggaaaatgttattattccacttttgaagagaaggttata
gctgcttatcaaattttgagagaaaatggacatctgataatgaatcttttccttctcatg
ttggctactggtattccagaattaacttcagtttctgatatcaaatggctgcgtgattgt
ttggttcttgataagtcaccagaagaggctgaacaacactttagagataagattacaaag
gctcttgcaaacacaaaatcccaattcaacgactttgtccacattgtaaaacataaataa

  All links  
Gene (79)   
   RefGene (75)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   JGI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (86)   

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