KEGG   Numida meleagris (helmeted guineafowl): 110401183
Entry
110401183         CDS       T06015                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
nmel  Numida meleagris (helmeted guineafowl)
Pathway
nmel00562  Inositol phosphate metabolism
nmel01100  Metabolic pathways
nmel04020  Calcium signaling pathway
nmel04070  Phosphatidylinositol signaling system
nmel04081  Hormone signaling
nmel04082  Neuroactive ligand signaling
nmel04261  Adrenergic signaling in cardiomyocytes
nmel04270  Vascular smooth muscle contraction
nmel04310  Wnt signaling pathway
nmel04371  Apelin signaling pathway
nmel04540  Gap junction
nmel04621  NOD-like receptor signaling pathway
nmel04912  GnRH signaling pathway
nmel04916  Melanogenesis
Module
nmel_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:nmel00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    110401183 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    110401183 (PLCB2)
   04371 Apelin signaling pathway
    110401183 (PLCB2)
   04020 Calcium signaling pathway
    110401183 (PLCB2)
   04070 Phosphatidylinositol signaling system
    110401183 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    110401183 (PLCB2)
   04081 Hormone signaling
    110401183 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    110401183 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    110401183 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    110401183 (PLCB2)
   04916 Melanogenesis
    110401183 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110401183 (PLCB2)
   04270 Vascular smooth muscle contraction
    110401183 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:nmel04131]
    110401183 (PLCB2)
Enzymes [BR:nmel01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     110401183 (PLCB2)
Membrane trafficking [BR:nmel04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    110401183 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    110401183 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh C2 EF-hand_like M157_N_1 NAD_binding_4
Other DBs
NCBI-GeneID: 110401183
NCBI-ProteinID: XP_021257662
Position
6:complement(2098341..2150370)
AA seq 1211 aa
MSMLTPVLQPPEVKEYLSKGERFIKWDDETASASPVILRVDPKGFYLYWTYQNKEMEILD
ITSIRDTRVGRFAKIPKCQKLREVFNLDYPHSTFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGKSWAEDIMAIVQNPLTYNASRYTFLEKILVKLKMQLNAEGKIPVRNIFQMFPADRKR
VEAALSACHLPKGKNDAINPEDFPETVYKTFLMNLCPRPEIDEIFTSHHFKAKPYMTKEH
LAKFINKKQRDSRLNDILFPPAKPEQVQSLIEKYEPSVINIQRGQLSPEGMVWFLCGPEN
NVIALDKLLLYQDMTQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSLYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTEPLEKYPLKPGVPLPSPKDLLGKILIKNKKKQFVSEKRQNSMKKGK
NVEPEITEQPALTDAEDTVWAGDVAEEEPEEEDDQLGNLDEEEIKKMQSDEGTAGLEVTA
YEEMSSLVNYIQPIKFDSFEVSAQKNRSYVISSFTELKAYDLLTKFPMQFVEYNKRQMSR
IYPKGTRMDSSNYMPQMFWNVGCQMVALNFQTMDVPMQQNMALFEFNGQCGYLLKHEFMR
RPDKQFDPFSVDRIDVVVASTLSVTILSGQFLSDRSVKTYVEVELFGLPRDTKRKYRTKL
TSTANSINPVWKEEPFVFEKIMMPELASLKIAAFEEGGKFIGHRVIPITAVHSGYHHVCL
RSESNMPLTMPSLFVYLEVKDYVPDAWADLTIALSNPIKFFNLQEKRSVNLKDGSEVERP
DMQRNFSFSENNGIAESSRKFSTPFANGPAGAAALVKDGNVKEVTQLAEPQTASLAELQQ
MKLFLKLLKKQEKELKELERKGSKRREELLQKYSVLFLEPVCPGGKKRSMHSRKTQKKRS
LTAGDAGTCVHPVEMAESLDSRVVELKERLEMELVRLGEEYHDGIRRRKEQHATEQTAKI
TELAREKQTAELKALKESSESNIKDIKKKLEAKRVDRIQVMMRSTSDKAAQERLKKEINN
SHIQEVVQTIKLLTEKTARYQQKLEEKQAENLRAIQEKESQLQQEAAAEYEEKLKSLSVE
VQETVKNYMREVFPEGPEIQKEAVLSRPVEEQGSTKQLEEKSPAAEVSRLTAATAEPPGA
KTDINFEESIL
NT seq 3636 nt   +upstreamnt  +downstreamnt
atgtcaatgcttacccctgtcctgcagcccccagaggtgaaggagtatctgtccaagggc
gaacgcttcatcaaatgggacgatgaaactgcgagtgcttctcctgtgattcttcgggtg
gatccaaagggcttttatttatactggacgtatcagaacaaggaaatggaaattctggat
ataaccagcatccgagacacccgagtagggcgatttgccaaaatccccaagtgccagaag
ctccgtgaggtttttaacttggattaccctcacagcacctttctgctgaaaactctgacc
gttgtatccggccctgacatggtggacctcactttccataacttcgtgtcctacaaggag
aatgttggcaagagctgggctgaggatattatggccattgttcagaatccccttacatac
aacgcttctcggtacaccttcctagagaaaatcctggtgaagctgaagatgcagctgaat
gcagagggaaagattcctgtcaggaatatttttcagatgtttcccgcagataggaagagg
gtggaagcagcattaagtgcttgtcatcttccaaaaggcaagaatgatgccatcaaccca
gaggacttccctgagaccgtgtataaaactttcctcatgaatctgtgtccacggcctgag
attgatgagatatttacttcacaccatttcaaagcaaagccctacatgaccaaagaacac
ttggcaaagtttatcaacaagaagcagcgagactctcgcctcaatgacatcctcttcccg
ccagcaaaacctgagcaggtgcagagcctgatagagaaatatgagcccagcgtcattaac
atccagagagggcagttgtctccagagggaatggtctggtttctctgcggccctgagaac
aacgtgatagcactggacaaattgctgctgtatcaggacatgacacagccgctctcacac
tacttcatcaattcatcacacaacacttatttaacagccggccagttttctggtatctca
tctcccgaaatgtatcgtcagacgctgctggccgggtgtcgctgtgtggagctggattgc
tggaagggccgtcccccagacgaggagcccatcatcactcacggcttcaccatgacaacg
gaaatcctcttcaaggatgccattgaggccattgcagaaagtgctttcaaaacatctctt
taccctgtcatcctctcctttgagaaccacgtggactcgcccaagcagcaggcaaagatg
gctgagtactgccgaaccatatttggagatatgctgctgacagagcctctggagaaatac
ccgctgaagccaggagttcctctgccaagtcctaaggatctcttagggaaaatcttaata
aagaacaaaaagaaacagtttgtatctgagaagaggcagaattctatgaagaaggggaag
aatgtggaaccagaaatcactgagcagccagcacttacggatgccgaagatactgtctgg
gcaggcgatgtggctgaagaggaaccagaggaagaggatgatcagctgggaaacctggat
gaagaggaaatcaaaaagatgcaatcagatgagggcactgctggtttggaagtgacagcg
tacgaggaaatgtccagcctcgttaattacatacagcccatcaaatttgactcctttgaa
gtctctgcccagaagaaccggagttatgtcatctcttccttcacggagctgaaggcttat
gatctgctgaccaagttccctatgcagtttgtggaatacaacaagcgccagatgagccgg
atttaccccaaaggcacccggatggactcctccaattacatgccccagatgttctggaat
gttggctgtcagatggtggcactgaacttccagaccatggacgtccccatgcagcagaac
atggctctgtttgagttcaacggccagtgtggctatctgctcaagcacgaattcatgcgg
cgtccagacaagcagtttgaccctttctcagtggaccgcattgatgtggtggtggcaagc
accctgtctgtcacgatactttctggtcagttcctctcagaccgcagcgtgaagacgtat
gtggaagtggagctgtttgggttgccaagggacacgaagcgcaaatacagaaccaaactg
acctccaccgccaattccatcaatcccgtttggaaagaagaaccttttgtttttgaaaag
atcatgatgcctgagctggcgtcactgaaaattgcagcttttgaggaaggagggaagttc
attggtcatcgtgtcattcccattactgcagtgcactcgggctatcaccacgtttgtctc
cgcagtgaaagtaacatgccgctcaccatgccctctctatttgtgtacctggaagtcaag
gattacgtccctgatgcttgggcagatctgactattgctctctccaatccaattaagttc
ttcaatctgcaagaaaagagatcagttaatctgaaagatggctcggaggtggagaggcct
gacatgcagaggaacttctcattctctgaaaataatgggatagcagagtcctccaggaaa
ttcagcaccccttttgcaaacgggcctgcaggagcagcagctctggtcaaggatggaaac
gtgaaggaagtgacacagcttgcagagcctcagacagccagcctcgcagagctgcagcag
atgaagctcttcctgaagctgctgaagaagcaggagaaagagctgaaggagctggagcgg
aaaggaagtaaacggagagaagagttgctgcagaaatattctgttctctttttggagcct
gtctgccctggaggcaagaaaaggtcgatgcactccaggaaaacccagaagaagaggagc
ttgacagcaggtgatgctggtacctgcgtgcatcctgtagaaatggcagaaagccttgat
agccgagttgtggaactgaaagagaggctggagatggagcttgtccgcctgggggaagaa
taccatgatgggattcgaaggaggaaagagcagcacgccacagagcaaacggccaagata
acagagctagccagagagaagcagacagctgagctgaaagcactgaaggagtcatcagaa
agcaacattaaagacattaagaagaagctggaggcgaagcgagtggaccgaatccaagtc
atgatgaggagtactagcgacaaggctgctcaggagaggttgaagaaagaaattaataac
tctcacatccaggaagtggtccaaacaatcaaactgctgacagaaaagacagccaggtat
cagcagaagctggaagagaagcaggcagagaatctgagggcaatccaagagaaagaaagc
cagctccagcaggaggcagcggcagaatacgaggagaaattgaaaagtctgagtgtggag
gtgcaggagacagtgaagaactacatgagagaggtctttcctgaggggccagagattcag
aaggaagcagttctgagcaggcccgtggaagaacaaggctctaccaagcaactagaagag
aagagcccagcagcagaggtgtcaaggctgacagcagctacggctgagcctccaggagcc
aaaacagacatcaattttgaggaaagcatactgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (6)   
   RefSeq(nuc) (4)   
   GenBank (1)   
   EMBL (1)   
Protein domain (9)   
   Pfam (9)   
All databases (20)   

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