KEGG   Nyctereutes procyonoides (raccoon dog): 129511620
Entry
129511620         CDS       T09008                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
npo  Nyctereutes procyonoides (raccoon dog)
Pathway
npo01522  Endocrine resistance
npo04010  MAPK signaling pathway
npo04015  Rap1 signaling pathway
npo04068  FoxO signaling pathway
npo04071  Sphingolipid signaling pathway
npo04114  Oocyte meiosis
npo04148  Efferocytosis
npo04218  Cellular senescence
npo04261  Adrenergic signaling in cardiomyocytes
npo04370  VEGF signaling pathway
npo04380  Osteoclast differentiation
npo04517  IgSF CAM signaling
npo04519  Cadherin signaling
npo04550  Signaling pathways regulating pluripotency of stem cells
npo04611  Platelet activation
npo04613  Neutrophil extracellular trap formation
npo04620  Toll-like receptor signaling pathway
npo04621  NOD-like receptor signaling pathway
npo04622  RIG-I-like receptor signaling pathway
npo04625  C-type lectin receptor signaling pathway
npo04657  IL-17 signaling pathway
npo04658  Th1 and Th2 cell differentiation
npo04659  Th17 cell differentiation
npo04660  T cell receptor signaling pathway
npo04664  Fc epsilon RI signaling pathway
npo04668  TNF signaling pathway
npo04670  Leukocyte transendothelial migration
npo04714  Thermogenesis
npo04722  Neurotrophin signaling pathway
npo04723  Retrograde endocannabinoid signaling
npo04728  Dopaminergic synapse
npo04750  Inflammatory mediator regulation of TRP channels
npo04912  GnRH signaling pathway
npo04914  Progesterone-mediated oocyte maturation
npo04917  Prolactin signaling pathway
npo04926  Relaxin signaling pathway
npo04932  Non-alcoholic fatty liver disease
npo04933  AGE-RAGE signaling pathway in diabetic complications
npo04935  Growth hormone synthesis, secretion and action
npo04936  Alcoholic liver disease
npo05014  Amyotrophic lateral sclerosis
npo05020  Prion disease
npo05022  Pathways of neurodegeneration - multiple diseases
npo05132  Salmonella infection
npo05133  Pertussis
npo05135  Yersinia infection
npo05140  Leishmaniasis
npo05142  Chagas disease
npo05145  Toxoplasmosis
npo05152  Tuberculosis
npo05161  Hepatitis B
npo05163  Human cytomegalovirus infection
npo05167  Kaposi sarcoma-associated herpesvirus infection
npo05169  Epstein-Barr virus infection
npo05170  Human immunodeficiency virus 1 infection
npo05171  Coronavirus disease
npo05205  Proteoglycans in cancer
npo05208  Chemical carcinogenesis - reactive oxygen species
npo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
npo05415  Diabetic cardiomyopathy
npo05417  Lipid and atherosclerosis
npo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:npo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129511620 (MAPK12)
   04015 Rap1 signaling pathway
    129511620 (MAPK12)
   04370 VEGF signaling pathway
    129511620 (MAPK12)
   04668 TNF signaling pathway
    129511620 (MAPK12)
   04068 FoxO signaling pathway
    129511620 (MAPK12)
   04071 Sphingolipid signaling pathway
    129511620 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    129511620 (MAPK12)
   04519 Cadherin signaling
    129511620 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    129511620 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    129511620 (MAPK12)
   04218 Cellular senescence
    129511620 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    129511620 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129511620 (MAPK12)
   04613 Neutrophil extracellular trap formation
    129511620 (MAPK12)
   04620 Toll-like receptor signaling pathway
    129511620 (MAPK12)
   04621 NOD-like receptor signaling pathway
    129511620 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    129511620 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    129511620 (MAPK12)
   04660 T cell receptor signaling pathway
    129511620 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    129511620 (MAPK12)
   04659 Th17 cell differentiation
    129511620 (MAPK12)
   04657 IL-17 signaling pathway
    129511620 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    129511620 (MAPK12)
   04670 Leukocyte transendothelial migration
    129511620 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    129511620 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    129511620 (MAPK12)
   04917 Prolactin signaling pathway
    129511620 (MAPK12)
   04926 Relaxin signaling pathway
    129511620 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    129511620 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    129511620 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    129511620 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    129511620 (MAPK12)
   04722 Neurotrophin signaling pathway
    129511620 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    129511620 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129511620 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    129511620 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    129511620 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    129511620 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    129511620 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    129511620 (MAPK12)
   05161 Hepatitis B
    129511620 (MAPK12)
   05171 Coronavirus disease
    129511620 (MAPK12)
   05163 Human cytomegalovirus infection
    129511620 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129511620 (MAPK12)
   05169 Epstein-Barr virus infection
    129511620 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    129511620 (MAPK12)
   05135 Yersinia infection
    129511620 (MAPK12)
   05133 Pertussis
    129511620 (MAPK12)
   05152 Tuberculosis
    129511620 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    129511620 (MAPK12)
   05140 Leishmaniasis
    129511620 (MAPK12)
   05142 Chagas disease
    129511620 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    129511620 (MAPK12)
   05020 Prion disease
    129511620 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    129511620 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    129511620 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    129511620 (MAPK12)
   05415 Diabetic cardiomyopathy
    129511620 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    129511620 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    129511620 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    129511620 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129511620 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:npo01001]
    129511620 (MAPK12)
Enzymes [BR:npo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     129511620 (MAPK12)
Protein kinases [BR:npo01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   129511620 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH RIO1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 129511620
NCBI-ProteinID: XP_055184441
Position
Unknown
AA seq 379 aa
MSSPPPARRGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRSGARVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENAPTPPGTPASPQVIGLLDVFTPDETLDDFTDFYLV
MPFMGTDLGKLMKHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELK
ILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKG
SDHLDQLKEIMKVTGTPPAEFVQRLQSAEAKNYMKGLPELQKKDFASILTNASPLAVNLL
EKMLVLDAEQRVTAAEALTHPYFESLQDTEEEPKAQKYDESFDDVDRTLDEWKRVTYKEV
LSFKPPRQLGTKVSKETAL
NT seq 1140 nt   +upstreamnt  +downstreamnt
atgagctccccgccgcccgcccgcaggggcttctaccgccaagaggtgaccaagacggcg
tgggaggtgcgcgcagtgtaccaggacctgcagcccgtgggctcgggcgcctacggggcc
gtgtgctcggctgtggacagccgcagcggcgcccgggtggccatcaagaagctgtaccgg
cccttccagtccgagctgtttgccaagcgcgcctaccgcgagctgcgcctcctcaagcac
atgcgccacgagaacgcccccactccaccaggtactccggcctccccccaggtcattggg
ctgctggacgtgttcactcctgatgaaaccctggatgatttcacagacttttacctggtg
atgccattcatgggaactgacctgggcaagctcatgaagcacgagaagctgagtgaggat
agaatccagttccttgtgtaccagatgctgaaggggctaaagtacatccacgctgctggc
atcatccacagggacctgaagcccggcaatctggcagtgaatgaggactgtgagctgaag
atcctggacttcggcctggccaggcaggcagacagcgagatgactggctacgtggtgacc
cggtggtaccgggcgcctgaggtcatcttgaactggatgcgctacacgcagacagtggac
atctggtccgtgggctgcatcatggcagagatgatcacggggaagacactgttcaagggc
agtgaccacctggaccagctgaaggagatcatgaaggtgacagggacgcctcccgccgag
ttcgtgcagaggctgcagagtgccgaggcgaagaactacatgaagggcctccctgagttg
cagaagaaggattttgcctccatcctgactaatgcaagccccctggccgtgaacctcctg
gagaagatgctggtgctggacgcagagcaacgggtgacggcggccgaggcgctgacccac
ccatacttcgagtccctgcaggacacggaggaggagcccaaggcccagaagtacgacgag
tcctttgatgatgtggaccgcacgctggatgagtggaagcgtgtcacatataaagaagtg
ctcagcttcaagcctccccggcagctggggaccaaggtctccaaggagacagccctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (7)   
   Pfam (7)   
All databases (17)   

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