KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110572939
Entry
110572939         CDS       T08474                                 
Symbol
AP2A1
Name
(RefSeq) AP-2 complex subunit alpha-1 isoform X2
  KO
K11824  AP-2 complex subunit alpha
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04142  Lysosome biogenesis
nsu04144  Endocytosis
nsu04721  Synaptic vesicle cycle
nsu04961  Endocrine and other factor-regulated calcium reabsorption
nsu05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    110572939 (AP2A1)
   04142 Lysosome biogenesis
    110572939 (AP2A1)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    110572939 (AP2A1)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    110572939 (AP2A1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    110572939 (AP2A1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:nsu04131]
    110572939 (AP2A1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:nsu04147]
    110572939 (AP2A1)
Membrane trafficking [BR:nsu04131]
 Endocytosis
  Clathrin-mediated endocytosis
   AP-2 complex
    110572939 (AP2A1)
Exosome [BR:nsu04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   110572939 (AP2A1)
SSDB
Motif
Pfam: Adaptin_N Alpha_adaptin_C Alpha_adaptinC2 Cnd1 HEAT_GCN1 HEAT_2 RIX1 HEAT_MROH2B_1st TOR1L1_N DUF4003
Other DBs
NCBI-GeneID: 110572939
NCBI-ProteinID: XP_021537047
UniProt: A0A2Y9GDF7
Position
16:complement(6651998..6683599)
AA seq 956 aa
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASP
DLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSA
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKV
QHSNAKNAILFETISLIIHYDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSE
FSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCDRSNAKQIVSEMLRYLETADYAI
REEIVLKVAILAEKYAVDYSWYVDTILNLIRIAGDYVSEEVWYRVLQIVTNRDDVQGYAA
KTVFEALQAPACHENMVKVGGYILGEFGNLIAGDPRSSPPVQFSLLHSKFHLCSVATRAL
LLSTYIKFINLFPETKATIQGVLRAGSQLRNADVELQQRAVEYLTLSSVASTDVLATVLE
EMPPFPERESSILAKLKRKKGPGAGSALDDGRRDPSSNDINGGVEPTPSTVSTPSPSADL
LGLRAAPPPAAPPATSGAGNLLVDVFSDGPAAQPSLGPAPEEAFLSPGPEDIGPPIPEAD
ELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQFQNFLPTVVHPGDL
QTQLAVQTKRVAAQVDGGAQVQQVLNIECLRDFLTPPLLSVRFRYGGAPQSLTLKLPVTI
NKFFQPTEMAAQDFFQRWKQLSLPQQEAQKIFKANHPMDAEVTKAKLLGFGSALLDNVDP
NPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLRTSKEPVSRHLCELLAQQF
NT seq 2871 nt   +upstreamnt  +downstreamnt
atgccggccgtctccaagggcgatgggatgcgggggctcgcggtgttcatctccgacatc
cggaactgtaagagcaaagaggcagagattaagagaatcaacaaggaactggccaatatc
cgctctaagttcaaaggggacaaagccttggatggctacagtaagaaaaaatatgtgtgt
aaactgctgttcatcttcctgcttggccacgacattgactttgggcacatggaggccgtg
aacctgctcagctccaacaagtacacggagaagcagataggttacctcttcatctcggtt
ctggtgaactcaaactccgagctgatccggctcatcaacaacgccatcaagaacgacctg
gccagccgcaacccgaccttcatgtgcctggcccttcactgcatcgccaacgtgggcagc
cgtgagatgggcgaggcctttgccgctgacatcccacgcatcctggtggctggggacagc
atggacagcgtgaaacagagcgcagccctgtgcctactacggctgtacaaggcctcaccc
gacttagtgcccatgggcgagtggacggcccgggtggtgcacctgctcaacgaccagcac
atgggtgtggtcacggcggctgtcagtctcatcacctgtctctgcaagaagaacccggac
gacttcaagacgtgcatctccctggctgtgtctcgcctgagccggattgtctcgtcggcc
tccaccgacctccaggactacacctactacttcgtcccggcgccctggctgtcggtgaaa
ctcctgcgactgttacagtgctacccaccaccagaggatgctgccgtgaaggggcggctg
gtggagtgtctggagaccgtgctcaacaaggcccaggagccccccaagtccaagaaggtc
cagcactccaacgccaagaatgccatcctcttcgagaccatcagcctcatcatccactac
gacagtgagcccaacctcctggtgcgggcctgtaaccagctgggccagttcctgcagcac
cgggagaccaacctgcgctacctggccctggagagtatgtgcacgctggccagctccgag
ttctcccatgaggcggtcaagacccacatcgacaccgtcatcaacgctctcaagacggag
cgggacgtcagtgtgcgacagcgggccgctgacctcctctatgccatgtgtgaccggagc
aacgccaagcagatcgtgtcagaaatgctgcggtacctggagacggcggactatgccatc
cgtgaagagattgtgctgaaggtggccatcctggccgagaagtacgcagtagactatagt
tggtacgtggacaccatcctcaacctcatccgcattgcgggcgactacgtgagtgaggag
gtgtggtaccgtgtgctgcagatcgtcaccaaccgtgacgacgtccagggctacgctgcc
aagaccgtctttgaggcgctccaggcccccgcctgccatgagaacatggtgaaggtcggc
ggctacatcctcggggagtttgggaatctgattgctggggacccccgctccagcccccca
gtgcagttctctctgctgcactccaagttccacctctgcagcgtggccacccgggccctg
ctgctgtccacctacatcaagttcatcaacctcttcccggagaccaaggccaccatccag
ggcgtgctgcgggctggctcccagctgcgcaacgctgacgtggagctgcagcagcgcgcc
gtcgagtacctcacgctcagctcggtggccagcacggatgtcctggccacggtgctggag
gagatgccgcccttcccggagcgggagtcgtccatcctggccaagctgaaacgcaagaag
gggcctggggctggcagcgccctggatgatggccggagggaccccagcagcaatgacatc
aatgggggcgtggagcccacccctagcactgtgtcgacgccctcaccctctgccgacctc
ctggggctgcgggcagcccctcccccagccgcacccccagcgacctcgggtgcagggaac
ctcctggtggacgtcttctccgacggcccggctgcccagcccagcctggggcccgccccc
gaggaggccttcctcagcccaggtcctgaggacatcgggccgcccatcccagaagccgat
gagctgctgaataagttcgtgtgcaagaataatggggtcctgtttgagaaccagctgttg
cagattggagtcaagtcggagttccggcagaacttgggccgtatgtatctcttctatggc
aacaagacgtccgtgcagttccagaacttcttgcccactgtcgtccaccctggagacctc
cagactcagctggcagtgcagaccaagcgcgtggccgcgcaggtggacggtggggcgcag
gtgcagcaggtgctcaacatcgagtgtctgcgggacttcctgacgcccccgctcctgtcc
gtgcgcttccggtacgggggcgccccccagtccctcaccctgaagctcccggtgaccatc
aacaagttcttccagcccacggagatggcggcccaggatttcttccagcgctggaagcag
ctgagccttccccaacaggaggcgcagaaaatcttcaaagccaaccaccccatggatgca
gaagtcactaaggcaaaactcctggggtttggctctgctctcctggacaatgtggacccc
aaccctgagaacttcgtgggggctggaatcatccagactaaagccctgcaggtgggctgt
ctgctccggctggagcccaatgcccaggctcagatgtaccggctgaccctgcgcaccagc
aaggaacctgtctcccgtcacctgtgtgagctgctggcccagcagttctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (10)   
   Pfam (10)   
All databases (19)   

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