KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110593901
Entry
110593901         CDS       T08474                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04310  Wnt signaling pathway
nsu04390  Hippo signaling pathway
nsu04519  Cadherin signaling
nsu04550  Signaling pathways regulating pluripotency of stem cells
nsu04810  Regulation of actin cytoskeleton
nsu04934  Cushing syndrome
nsu05010  Alzheimer disease
nsu05022  Pathways of neurodegeneration - multiple diseases
nsu05165  Human papillomavirus infection
nsu05200  Pathways in cancer
nsu05206  MicroRNAs in cancer
nsu05210  Colorectal cancer
nsu05213  Endometrial cancer
nsu05217  Basal cell carcinoma
nsu05224  Breast cancer
nsu05225  Hepatocellular carcinoma
nsu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    110593901 (APC2)
   04390 Hippo signaling pathway
    110593901 (APC2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    110593901 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    110593901 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110593901 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110593901 (APC2)
   05206 MicroRNAs in cancer
    110593901 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    110593901 (APC2)
   05225 Hepatocellular carcinoma
    110593901 (APC2)
   05226 Gastric cancer
    110593901 (APC2)
   05217 Basal cell carcinoma
    110593901 (APC2)
   05213 Endometrial cancer
    110593901 (APC2)
   05224 Breast cancer
    110593901 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    110593901 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110593901 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    110593901 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    110593901 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nsu01009]
    110593901 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:nsu03036]
    110593901 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:nsu04812]
    110593901 (APC2)
Protein phosphatases and associated proteins [BR:nsu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     110593901 (APC2)
Chromosome and associated proteins [BR:nsu03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    110593901 (APC2)
Cytoskeleton proteins [BR:nsu04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     110593901 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Arm Suppressor_APC APC_r Arm_APC_u3 SAMP ARM_PUB ZER1-like_2nd SSNA1 PEA2_C bZIP_1 Par-4_C HALZ Sec7-like_HUS Wtap CCDC138_cc
Other DBs
NCBI-GeneID: 110593901
NCBI-ProteinID: XP_021561017
UniProt: A0A2Y9IAM2
Position
1:complement(213763631..213777924)
AA seq 2265 aa
MASSVAPYEQLVRQVEALKAENSHLRQELQDNSSHLSKLETETSGMKEVLKHLQGKLEQE
AGVLVSLGQTEVLEQLKALQMDMTSLYKLKSQPPALGPEPTARTPEESPVHGSGPSKDSS
GELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQM
DLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDQELLSAQDRVQQTEPQA
LLAVKSVPVDEDPEPEVPTHPEDGVPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSS
SPESCVAMRRSGCLPLLLQILHGAEAGAGGRNGSPGAPGAKDARMRANAALHNIVFSQPD
QGLARKEMRVLHVLEQIRAYCETCWDWLQARDGAEGGNGGAPVPIEPQICQATCAVMKLS
FDEEYRRAMNELGGLQAVADLLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVANKA
TLCARRGCMEAIVAQLASESEELHQVVSSILRNLSWRADINSKKVLREVGSMTALMQCVL
RASKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESGGG
ILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSPRDQEL
LWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKYQSTAAAVSPGACAPSLYVRK
QRALEAELDTRHLAQALDHLEKQGLPEAEADAASKKPLPSLRHLDGLARDYASDSGCFDD
DEAPSLAAAAATAEPASPAVLSLFLGSPFLQGQALARAPPARRSGPEAEKEAGGEVAVAA
RAKAKLALAVARIDRLVEDISALHTSSDDSFSLSSGDPGQEVPREGRAQSCSPCRRPEGR
RPEPGSRAHPLLRLKAAHTSLSNDSLNSGSTGDGRCPREHTRPCPLAVLAEHREGPPCNQ
VRPSRLDLHLPGSQEPASRDSSAADARVHTIKLSPTYQHVPLFEGHPRAGMGPLAPGARK
QAWLPTDGLSKVPEKLVADTGPLCLSRCSSLSSLSSAGHPGPSEAGDLDSDSSLEGLEEA
GPGKADLDGAWLGPGAASLPVAIPAPQRGRGLGVEDTTPSSSSENCVQETPLVLSRCSSV
SSLSSFESPSIASSVPSDPCSGLGSGTVSPSELPDSPGQTMPPSRSKTPPLVPVPPGERE
STQFSLQWESYVKRFLDIADRRERCRLPSELDAGSVRFTVEKPDENFSCASSLSALALHE
HYVQKDVELRLLPPACPERGGGGGGPGLHFAGHRRRDEAGGCLEGPAAADQELELLRECL
GAAVPARLRKVASALVPGRRALPVPVYMLVPAPARVEDSCTDSAEGTPVTFSSATSLSDE
TLQGPPRDPPGGPSDRQKPSGREAPAGQATGHRHRARGAGRSTEQARGAGGSRVGLELPL
RGPSSACTDRASPRPIPARGDGAPQSLCLTTPTEEAVYCFYDNDSDEEPSEAQVNPRRAS
AIPRAVRREHQAGRKEVQALPKVTPKATPGARAQPSLIADETPPCYSLSSSASSLSEPEP
PAPPASRPHAPQPAANKVPGTGGARNGPPSPRAETGLLRRCVGSAVPRRRLQASGPRRRK
PQAAQPDKRPAETLRERGDEAASSDHASDLDSVEWRAIQEGANSIVTWLHQAAAAATHEA
SSGSDSILSGSGLSGSSTLQPPLHRKGRRLQAGGQAGSTARPEKRDSALAQHSTRGPEKL
RGAQKTACRVPAVLRGRTVIYVPSPAPRAPPRGHAGTCMAPRKMAPPSPAQPAAPAKTPS
PGQQRSRSLHRPGKISELAALSPPQRSATPPARLAKAPSSGSSPASPASQPPTRRPPPGA
QAAGPLPGPRASLVPQTPTRALLSKQHKTQKSPVRIPFMQRPARRGPPPLARAAPEPGPR
GRAAAEGSPGARGGRLGLVRVASARSSGSESSDRSGFRRQLTFIKESPGLLRRRRSELSA
PEAAPPASQGGSPRRSRPALPAVFLCSSRCDELRATPRQVPVPQRAPVARPSPSERLARR
PSSESPSRLPVRTPAARPETVKRYASLPHISVARRPDAAAPGPTTDAARRSSDGEARPLP
RVAAPGTTWRRIRDEDVPHILRSTLPATALPLMGAPSEEGPSGPPQRKTSDAVVQTEDFA
AAKTNSSTSPSLESRAPPQAPVSGPTALLGSDVDGPGPTKAPTSAPFVHEGLGVAAGGFP
ASRHGSPSRSARVSPFNYVPSPMVAATTDLAAEKAPTAAPASLLE
NT seq 6798 nt   +upstreamnt  +downstreamnt
atggcgagctccgtggcaccctacgagcagctggtgcggcaggtggaggccctgaaggcc
gagaacagtcacctgaggcaggagctgcaagacaattccagccacctgtccaagctagag
acggagacatccggcatgaaggaggtcctgaagcacttacagggcaagctggaacaggag
gccggagtgctggtgtccttggggcagaccgaggtcctggagcagctgaaagccctgcag
atggacatgaccagcctgtacaaactcaagtcccagcccccagccctaggacccgagccc
actgcgcggacccccgaagaaagtcccgtccacggctctgggccctctaaggacagctct
ggggagctgagccgagctaccatccggctgctggaggaactggaccgggaacggtgcttc
ctgttgaacgagatcgagaaggaggagaaggagaagctctggtattactcacagctgcag
ggcctgtccaagcgcctggacgagctcccgcacgtggagacgcagttctcgatgcagatg
gacctgatccggcagcagctggagttcgaggcccagcacatccgctcgctgatggaggag
cgcttcggcacctcggacgagatggtgcagcgggcgcagatccgtgcttcgcgtctggag
caaatcgatcaggaactgctgtccgcgcaggaccgcgtgcaacagaccgagccccaggcc
ctgctggcggtgaagtcagtgccggtagatgaggacccagagcctgaggtccccacgcac
cctgaggatggtgtccctcagccgggcaacagcaaggtggaggtggtcttctggttgctg
tccatgctggcgacgcgcgaccaggaggacacggcccgcaccctgctggcgatgtccagc
tcgccggagagctgcgtggctatgcgccgctcggggtgcctgccgctgctgctgcagatc
ctgcacggcgccgaggctggcgcggggggtcggaacgggagccccggggcgccgggagcc
aaggatgcgcgcatgcgcgccaacgcggcgctgcacaacattgtcttctcgcagccggac
cagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcagatccgggcctac
tgtgagacgtgctgggactggctgcaggccagggacggcgccgaaggcggcaacggcggc
gccccggtgcccattgagcctcagatctgccaggccacctgtgccgtgatgaagctgtcc
tttgatgaggaataccgccgtgccatgaacgagctgggtgggctgcaggccgtagcggac
ttgctgcaggttgactacgagatgcacaagatgacgcgggacccgctcaacctcgcccta
cgccgatacgctggcatgaccctcaccaacctcacctttggggatgtcgccaacaaggcc
acgctgtgtgcccgccggggctgcatggaggccattgtggcccagctggcttccgagagc
gaagagctccaccaggtggtgtccagcatcctgcgcaacctgtcctggcgggccgacatc
aacagcaagaaggtgctgagggaggtcggcagcatgactgctctgatgcagtgtgttctg
agagcctccaaggagtccaccctgaagagcgtgctcagcgccctgtggaacctgtcagca
cacagcactgagaacaaggcggccatctgtcaggtggacggcgcgctgggcttcctggtg
agcacgctgacttacaagtgccagagcaactccctggccatcatcgagagcggtggtggc
atcctgcgcaatgtgtccagcctcatcgccacccgcgaggactacagacaggtgctgcgg
gaccacaactgcctgcagacgctgctccagcacctgacgtcccacagcctgaccatcgtg
agcaacgcctgcggcacgctctggaacctgtccgcccgcagcccgcgcgaccaggagctg
ctgtgggacctgggggccgtgggcatgctgcgcaacctggtgcactccaagcacaagatg
atcgccatgggcagcgccgccgccctgcgcaacctgctggcgcaccggcctgccaaatac
cagagcacggccgcggccgtgtcccccggcgcgtgcgcgcccagcctgtacgtgcggaag
cagcgggcgctggaggccgagctggacacgcggcacctggcgcaggcgctcgaccacctg
gagaagcagggcctgcccgaggccgaggccgacgccgcctccaagaagccgctgccgtcc
ctgcggcacctggacgggctggcccgggactatgcctcggactcgggctgctttgacgac
gacgaggcgccctccctggctgcggcagccgccaccgcggagcctgccagcccggccgtg
ctgtcgctcttcctggggagccccttcctgcaggggcaggcgctggcccgcgccccgcct
gcccgccgcagcggaccggaggcagagaaggaggccggcggggaggtggccgtggcggcc
agggccaaggccaagttggcgctggcagtggcgcggatcgaccggctggtggaggacatc
tccgccctacacacctcgtctgacgacagcttcagcctcagctctggggaccccgggcag
gaggtgccgcgcgaaggccgggcccagtcctgctccccttgccggcggcccgagggcagg
cggccggagcctggcagccgtgcccacccactactgcggctcaaggctgcccacaccagc
ctctccaacgacagtctcaacagcggcagcaccggtgatgggcgctgtccccgcgagcac
acacggccctgcccgctggccgtgctggccgagcaccgcgaggggcccccctgcaaccag
gtgcggcccagccggctggacctccatctgccggggagccaggagccggcatcccgggac
agctctgccgccgacgcccgcgtgcacaccatcaagctgtcgcccacctaccagcacgtg
ccgctcttcgagggccaccccagggcgggcatggggcccctggcccccggagcccggaag
caggcctggctgcccacggacggcctgagcaaggtgccggagaagctggtagcagacaca
gggccgctttgcctgtcccgctgcagctccctgtcctcgctgtcctcggctggccaccca
ggccccagtgaggccggggacctggacagtgactcgtccctcgaggggctggaggaggca
ggacctggcaaggcagacctggacggggcctggctcgggcccggggccgcctccctgccc
gtggccatcccggcaccccagaggggccggggcctgggggtcgaggacaccacgccgtcc
agctcctcggagaactgcgtgcaggagacgccgctggtgctgagccgctgcagctcggtg
agctccttgagcagtttcgagagcccgtccatcgccagctctgtccccagtgacccgtgc
agtgggctgggcagcggcacggtcagccccagcgagctgcccgacagccctgggcagacc
atgccacccagccgcagcaagacgcccccgctggtccccgtgccccccggcgagcgcgag
agcacccagttcagcttgcagtgggagagctacgtgaagcgcttcctggacatcgcggac
cgccgcgagcgctgccggcttccgtccgagctggacgcgggcagcgtgcgcttcactgtg
gagaagcccgacgagaacttctcgtgtgcttccagcctcagcgcgctggccctgcacgag
cactacgtgcagaaggacgtggagctgcggctgctgcccccggcctgccccgagcgtggt
ggcggcggtggcgggcctggcctgcactttgctgggcaccgccggcgggacgaggctggg
ggctgccttgaggggccggccgccgccgaccaggagctggagctgctgcgtgagtgcctg
ggggcggcggtgcccgcccggctccgcaaggtggcctcggccctggtgcccggccgccgt
gcactgcctgtgcccgtctacatgctggtgcctgcccccgcccgggtggaagactcctgc
accgactccgccgagggcacacctgtcaccttctccagtgccacctcactcagtgacgag
acactgcagggacctcccagggacccgcctggcgggccttcggacaggcagaagccctca
ggtcgtgaggccccggccgggcaggccacgggccataggcacagggcacggggtgcaggc
cggagcacagagcaggcccggggggcaggcgggagccgggtggggctggagctgcccctc
cgcgggccctcaagcgcctgcacggaccgggccagcccccgccccatccctgcgcgcggg
gacggggcaccgcagtcactgtgcctcacgacgcccaccgaggaggccgtgtactgcttc
tacgacaacgactccgatgaggagccctccgaggcgcaggtgaacccgcggcgggcgtca
gccatcccccgtgcagtaaggagagagcaccaggccggcaggaaggaggtgcaggccttg
cccaaggtcacgcccaaggccacgccaggcgcccgcgcccagcccagcctcatcgccgac
gagacgccaccatgctactccctgagctcctccgccagctccctcagcgagcctgagccc
ccggcgcccccggccagccggccccatgctccccagccagcggccaacaaggtaccaggc
actgggggtgcgcgtaacggccccccgagcccgcgggcggagacgggcctgctccggcgc
tgcgttggctccgcggtgcccaggcgcaggctgcaggcatcgggcccacggcgccgcaag
ccccaggctgcccagccagacaagcggccagcagagacgctccgggagcgcggggacgag
gcggcgagctcagaccatgcctcagaccttgacagcgtcgagtggcgtgccatccaggag
ggcgccaactccattgtcacgtggctgcaccaggcagcggcggcggccacccacgaggcc
tcgtctgggtctgactcgatcctgtccgggtctgggctgtccgggagctccaccctgcag
ccccccctgcacaggaagggacggcggctgcaggcggggggccaggcgggcagcaccgcg
aggccggagaaacgggactcggccctggcccagcacagcaccaggggccccgagaagctg
cgcggtgctcagaagaccgcgtgcagggtgccggccgtgctccggggacggaccgtgatc
tatgtgcccagcccggccccccgggccccgcccagaggccacgctggcacctgcatggca
ccaaggaagatggcacccccgagtcctgcgcagccagcagcccccgccaaaacccccagc
cccgggcagcagcggtctcgaagcctgcaccggccaggcaagatctcggagctggcggcg
ctgagccctccccagaggagcgccacaccgcccgcccgcctggccaaggccccctcatcc
ggctcctccccagcctctccagcctcccagccccctacgaggaggccgcccccaggcgcc
caggccgcagggcccctccccggccccagggcatctctggtgccccaaacacccacacgg
gctttgctgtccaagcagcacaagacacagaagtcacctgtgcggatccccttcatgcag
aggccagccaggcgggggccgccacccctggccagggcagccccagagccaggcccccgg
ggtcgggcagcagctgaaggaagccctggcgcccgagggggccgcctgggcctggtgcgc
gtggcctctgcccgctccagcggcagcgagtcctccgaccgctcgggtttccggcggcag
ctgacctttatcaaggagtccccgggcctgctgcgccgccgccgatcggaactgtccgcc
cctgaggctgcgccccccgcctcccagggtggctcaccccgccgcagtcgacctgcgctg
cctgctgtcttcctgtgctcctcacgctgcgacgagctgcgggcaaccccccggcaggtt
ccggtcccccagcgagcccccgtggccaggcccagtcccagcgagcggctggcccggcgc
cccagctccgagagtccgtcccgcctgcctgtccgcaccccggccgcacggcccgagacg
gtcaagcgctacgcctccctgccgcacatcagcgtggcccgcaggcccgacgcggctgcc
cccgggcccaccactgacgctgcccgacgcagcagcgatggggaggcccggccgctgcca
agggtggcggcaccgggcaccacgtggcgtcgcatccgggacgaggacgttccacacatc
ctgcggagcacgctgcccgccactgccctgccactgatgggcgccccgtctgaggagggc
cccagcggccccccacagcgcaagaccagcgatgccgtggtccagacggaggactttgct
gccgctaagaccaactccagcacatctccgagcctggaaagcagggcccccccccaggcc
ccggtcagcggccccactgccctccttggcagcgatgtggacgggcccggtcccaccaag
gcgcccacctctgctccctttgtccacgagggcctgggggtggctgcagggggctttcct
gccagccggcatggctcccccagccgctcagcccgtgtctcccccttcaactatgtgccc
agccccatggtggcagccaccactgacttggctgcagagaaagcccccaccgctgccccc
gccagcctcctggaatag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (18)   
   Pfam (18)   
All databases (25)   

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