KEGG   Ovis aries (sheep): 101104664
Entry
101104664         CDS       T03117                                 
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X3
  KO
K02085  adenomatosis polyposis coli protein
Organism
oas  Ovis aries (sheep)
Pathway
oas04310  Wnt signaling pathway
oas04390  Hippo signaling pathway
oas04550  Signaling pathways regulating pluripotency of stem cells
oas04810  Regulation of actin cytoskeleton
oas04934  Cushing syndrome
oas05010  Alzheimer disease
oas05022  Pathways of neurodegeneration - multiple diseases
oas05165  Human papillomavirus infection
oas05200  Pathways in cancer
oas05206  MicroRNAs in cancer
oas05210  Colorectal cancer
oas05213  Endometrial cancer
oas05217  Basal cell carcinoma
oas05224  Breast cancer
oas05225  Hepatocellular carcinoma
oas05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101104664 (APC)
   04390 Hippo signaling pathway
    101104664 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101104664 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101104664 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101104664 (APC)
   05206 MicroRNAs in cancer
    101104664 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101104664 (APC)
   05225 Hepatocellular carcinoma
    101104664 (APC)
   05226 Gastric cancer
    101104664 (APC)
   05217 Basal cell carcinoma
    101104664 (APC)
   05213 Endometrial cancer
    101104664 (APC)
   05224 Breast cancer
    101104664 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101104664 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101104664 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    101104664 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101104664 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:oas01009]
    101104664 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:oas03036]
    101104664 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:oas04812]
    101104664 (APC)
Protein phosphatases and associated proteins [BR:oas01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101104664 (APC)
Chromosome and associated proteins [BR:oas03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    101104664 (APC)
Cytoskeleton proteins [BR:oas04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     101104664 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u15 APC_u9 SAMP Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS
Other DBs
NCBI-GeneID: 101104664
NCBI-ProteinID: XP_027827242
Position
7:complement(1102838..1237286)
AA seq 2862 aa
MCTPLCSSALAASPASVPPCAVGSRSCGGGRGCVRQERKRPRCARASVRGASVWQEVLKQ
LQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGEC
SPVPMGSFPRRGFVNGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRID
SLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRITRIQQIEKDILR
IRQLLQSQATEAERSSQSKHEAGSREAERQNEGQGAAETSMAASGSGQGSTTRIDHETAS
VLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQS
GCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHSIVHSQPDDKRGRREIRVLHLL
EQIRAYCEACWEWQEAHEQGLDQDRNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELG
GLQAIAELLRVDCEMHGLTKDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALV
AQLQSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLS
ALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNE
DHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNL
IHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLS
ETFDNIDNLSPKASHRSKQRHKQNLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTV
LPSSSSSRGSLDSSRSEKDRSLERERGISLGNYHPATENPGTSSKRGLQIPTTAAQIAKV
MEEVSAIHTSQEDRSSGSTTELHCGTDERNALRRSSTTHTHANTYNFTKSENSNRTCPIP
YAKVEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHS
ANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHILEDEIKPNEQRQSRS
QSTAYPVYPESSDDKHLKFQPHFGQQECVSPYRSRAANGSETNRVGSNHGISQNVTQSLC
QEDDYEDDKPTNYSERYSEEGQHEEEERPTNYSIKYSEEKHHVDQPIDYSLKYTTDIPSS
QKPAFSFSKNSSGQSTKTEHISSSSENTSTTSSNAKRQNQLHPSSAQSRSGQTPKATSSS
CKVPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEVGCDQTTQEAESANTLQIAEIK
DNSGPRSNEDSVSKVPTVSQHIRTKSSRLQASGLSSESARHKAVEFSSGAKSPSKSGAQT
PKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPG
QTMPPSRSKTPPPPPPPPPPQTVQTKQEVPKNKAPSAEKRESGPKQAAVNAAVQRVQVLP
DADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPE
ESNENQEKEAEKPTDSEKDLLDESDDDDIEILEECIISAMPTKSSRKAKKPAQTTSKLPP
PVARKPSQLPVYKLLPSQNRLQAQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIE
SPPNELAAGEGVRAGAQSSEFEKRDTIPTEGRSTDEAQRGNASSVTVPELDDNKTEEGDI
LAECINSAMPKGKSHKPFRVKKIMDQVQQASMSSSGTNKNQLDGKTKKPTSPVKPIPQST
EYRTRVRKNTDSKNNLNAERNFSENKDSKKQHLKNNSKDLNDKLPNNEDGVRGSFTFDSP
HHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKENKESEAKVTNHTELTSN
QQSASKTPAVTKQPINRGQSKPVLQKQSTFPQSSKDMPDRGAATDEKLQNFAIENTPVCF
SRNSSLSSLSDIDQENNNNKENEPIKETEPPASQGEPGKPQASGYAPKSFHVEDTPVCFS
RNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKPDNEKHSPRNMSGILAEDLTLDLKD
IQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGI
SLGSPFHLTPDQEEKPFMNNKGPRILKPGEKSTLETKKIESENKGIKGGKKVYKSLITGK
VRSNSEISSQMKQPLPTNMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPS
EGQPATTSPRGTKPSVKSELSPVTRQASQTAASNKGPSRSGSRDSTPSRPAQQPLSRPMQ
SPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQT
GLSKNGSGIPRSESASKGLNQMSSNNGANKKVELFRMSSTKSSGSESDRSERPVLVRQST
FIKEAPSPTLRRKLEESASFESLSPSSRPDSPTRSQAHTPVLSPSLPDMSLPTHSSVQSG
GWRKLPPNLSPTIEYNDGRPVKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVS
TWRRTGSSSSILSASSESSEKAKSEDEKQVNSISGSKQTKENQVSTKGTWRKIKESEISP
TNSTSQTTSSGAANGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNSPPV
IDTVSEKGSPNPKDSKDNQGKQNVSNGSAPTRTVGLENRLNSFIQVDPPDQKGTETKPGQ
SNNPVPTSETNESSIAERTPFSSSSSSKHSSPSGTVAARVSPFNYNPSPRKSSTDGTSAR
PSQIPTPVSNNTKKRDSKPDSTEPSGTQSPKRHSGSYLVTSV
NT seq 8589 nt   +upstreamnt  +downstreamnt
atgtgcacccccctctgctcgagtgcgctcgccgcttcgcctgcttcggtgccgccctgt
gccgtcgggtcccggagctgcggcggcggcaggggctgtgtccggcaggagaggaagcgc
ccgcgctgcgcccgtgcttctgtccgcggggcgagcgtctggcaggaagtacttaaacaa
ctacaaggaagtattgaagatgaagctatggcttcttctggacagattgatttattagag
cgtcttaaagaacttaacttagatagcagtaatttccctggagtgaaactacgatccaaa
atgtccctccgttcttacggaagccgagaaggatctgtatctagtcgctcaggagagtgc
agtcccgttcctatgggttcatttccaagaagagggtttgtaaatggaagcagagaaaat
accggttatttagaagaacttgaaaaagagagatcattgcttcttgctgaccttgacaaa
gaagaaaaggaaaaagactggtattatgctcaacttcagaatctcactaaaagaatagac
agccttcctttaactgaaaatttttccttacaaacagatatgaccagaaggcagttggaa
tatgaggcaaggcaaatcagagttgcaatggaagaacagctaggtacttgccaggatatg
gaaaaacgagcacagcgaagaataaccagaattcaacaaatagaaaaggacatacttcgt
atacgacagcttttacagtcccaagcaacagaagcagagaggtcgtctcagagcaagcat
gaagcgggctcccgtgaagctgagcggcagaatgaaggtcaaggagcggcagaaaccagc
atggcagcctcgggaagcggccagggttcaacgacacgaatagaccatgaaacagccagt
gttttgagttctagtagcacacactctgctcctcgaaggctgacgagtcatctgggaacc
aaggtggaaatggtgtattcattgttgtcaatgcttggtactcatgataaggatgatatg
tcgcgaactttgctagctatgtctagctcccaggacagctgtatatccatgcgacagtct
ggatgtcttcctctcctcatccagcttttacatggcaatgacaaggactctgtgctgctg
ggaaattcccggggcagtaaggaggctcgggccagggccagcgcagcgctccacagcatc
gtccactcacagcccgatgacaagaggggcaggcgtgagatccgagtcctccatcttttg
gagcagatacgcgcgtactgcgaagcctgctgggagtggcaggaagcccacgagcaaggc
ctggaccaggacagaaatccaatgccagctcctgttgaacatcagatctgtcctgctgtg
tgtgttctaatgaaactttcgtttgatgaagagcatagacacgcaatgaatgaacttggg
ggactacaggccattgcagagttattgcgagtggactgtgaaatgcatgggcttactaag
gaccactacagtattactttaagacgatacgcaggaatggctttgacaaacttgactttc
ggagatgtagctaacaaggctactctctgctctatgaaaggctgcatgagagcgctcgtg
gctcagctccagtccgagagtgaggacttgcagcaggttattgcgagtgttttgaggaat
ctgtcttggagagcagatgtaaatagtaaaaagactttgcgtgaagttggaagtgtgaaa
gcactgatggaatgtgctttggaagtgaaaaaggagtcaaccctcaagagtgttttgagt
gccttatggaacctgtcggcacactgcactgagaataaagccgacatatgtgctgtagac
ggcgcacttgcgtttctggttggcactctcacttatcgcagccagaccaacactttagcc
atcattgaaagtggaggtggcatcttacggaacgtatccagcttgatagctacaaatgag
gaccacaggcaaatcctaagagagaataattgcttacagaccttattacaacacttgaaa
tctcacagtttgacaatagtcagtaatgcatgcggaaccttgtggaatctctcagcgaga
aaccctaaagaccaggaagcattgtgggacatgggagcggtcagcatgctcaagaacctc
attcattcaaagcacaagatgattgctatgggaagtgctgcagctttaaggaatctcatg
gcaaatagacctgcaaagtataaagatgccaatatcatgtctcctggttccagtctgcct
tctcttcatgtcaggaaacaaaaggccctggaagcagaattagatgctcagcatttatca
gaaacttttgacaatattgacaatttaagtcccaaagcatctcatcgtagtaagcagaga
cacaagcaaaatctctatggtgactatgtttttgacaccaatcgacatgatgataacagg
tcagacaattttaatactggaaacatgactgtcctatcaccatacttaaataccacagta
ttgcccagctcttcttcatcaaggggaagtttagatagctctcgttctgagaaagatcga
agtttggagagagaacgaggtattagcctaggcaactatcacccagcaacagaaaatcca
ggaacctcttcaaagcgaggtttgcagattcctaccactgcagcccagattgccaaagtc
atggaagaagtatcagctattcatacgtcccaggaagacagaagttctgggtctaccaca
gaactacactgtgggacagatgagaggaatgcactcagaagaagctctaccacccacaca
catgcaaacacttacaactttaccaagtcagaaaactcaaacagaacatgtccaatacca
tatgccaaagtggaatataagagatcttcaaatgatagtttaaacagtgtcagcagtagt
gacggttatggtaaaagaggtcagatgaaaccttcaattgaatcctattctgaagatgat
gaaagtaaattttgcagctatggtcagtatccagctgacttagcccataaaatacatagt
gcaaatcatatggatgataatgatggagagctagatacaccgattaattatagtcttaaa
tattccgatgaacagttgaactctgggaggcagagcccttcacagaatgaaagatgggca
agacccaaacatatcctagaagatgaaataaaaccgaatgagcagagacaatcaaggagt
caaagcacagcttatcctgtatatcctgagagcagcgatgataaacatctcaagttccaa
ccacactttgggcagcaggaatgtgtttccccatacaggtcaagagcagccaatggatct
gaaacaaatcgagtaggctctaaccatggaattagtcaaaatgtgacccagtctttgtgt
caagaagatgactatgaagatgataaaccaaccaactatagtgaacgttactctgaggaa
gggcagcatgaggaagaagagagaccaaccaattatagcataaaatacagtgaagaaaaa
catcacgtggatcagcctattgattatagtttaaaatacaccacagacattccttcttca
cagaaaccagcattttcattctcaaagaattcatctggacagagcacaaaaactgaacac
atctcttcaagcagcgagaatacgtccacaacttcatctaatgccaagaggcagaatcag
ctgcatccaagctcagcacaaagcagaagtgggcagaccccaaaagccacctcttcctct
tgcaaagtcccctctatcaaccaagaaacaatacagacttactgtgtagaagatacccca
atatgcttttcaagatgcagttcattatcatctttgtcatctgctgaagatgaagtaggg
tgtgatcagacaacgcaggaagcagagtccgctaacactctgcagatagccgaaatcaag
gacaacagcggacctaggtcaaatgaagattctgtgagtaaagttccaacagtgtcgcag
cacattagaaccaaatccagcagactccaggcttctggtctgtcttcagagtcagccagg
cacaaagctgttgaattttcttcaggggccaaatctccttccaagagtggtgctcagaca
cccaaaagtccgccagagcactacgttcaggagaccccactcatgttcagcagatgtact
tcggtcagttcacttgatagttttgagagtcgctcgattgccagctctgttcagagtgaa
ccctgcagtggaatggtaagtggcattataagccccagtgacctcccagatagccctgga
caaaccatgccaccaagcagaagtaaaacccctcctcctcctccacctcctcctcctcct
cagacagttcaaacgaagcaggaagtacctaaaaataaagcacctagtgctgaaaagaga
gaaagtggacctaagcaagccgcggtaaatgctgcagtacaaagggtccaggttcttcca
gatgctgatactctgttacattttgccacagagagtactcctgatggattttcttgttcg
tctagcctgagtgcactgagccttgatgagccatttattcagaaagatgtggaactaaga
ataatgcctccagttcaggaaaatgacaacgggaatgaaacagaaagtgagcagcctgaa
gaatcaaatgaaaaccaagaaaaagaggcagaaaaacccactgattctgaaaaagatctt
ttagatgagtcagatgatgatgatattgaaatactagaagagtgtataatttctgccatg
ccaacaaaatcttcacgcaaagccaaaaaaccagcccagactacttcgaaattacctcca
cctgtggcaaggaaaccaagtcagctccctgtatacaaacttctgccatcacagaacagg
ttacaggcacaaaagcatgttagttttacaccaggagatgatatgccacgggtgtattgt
gtagaagggacacctataaacttttccacagctacatctctgagtgatctaacgatagaa
tcccctccaaatgagttagctgctggagaaggggttagagcaggggcacagtcaagtgaa
tttgaaaaacgagataccattcctaccgaaggcagaagtacagatgaggctcaaagaggg
aacgcctcgtctgtcactgtacctgaactggatgacaataaaacagaagaaggtgatatt
cttgcagaatgcattaattctgctatgcccaaaggaaaaagtcacaagcctttccgtgtg
aaaaagattatggaccaggtccaacaagcatctatgtcttcatctggaactaacaaaaac
caattagatggtaagacaaagaaaccgacttcaccagtaaaacctataccacaaagtact
gaatacaggacacgtgtaagaaaaaatacagactcaaaaaataatttaaatgccgaaaga
aatttctcagaaaacaaagactcaaagaaacagcacttgaaaaataactccaaggacctc
aatgataaactgccaaataatgaagacggagtcagaggaagttttacttttgattcacct
catcactacacgcccattgaaggcactccatactgtttttcacgaaatgactctttgagt
tctctagattttgacgatgatgatgttgacctttccagggaaaaggctgaattaagaaag
gggaaggaaaataaagaatcagaagctaaagtgaccaaccacacagaactaacctcaaac
caacaatcagctagtaagacaccagctgttacaaagcagccaataaacagaggtcagtct
aaacccgtgctgcagaagcagtccacttttccccagtcttccaaagatatgccagacaga
ggggcagcaacagatgagaaattacagaatttcgctattgaaaatactccagtttgcttt
tctcgaaattcctctctaagctctcttagtgacattgatcaagaaaacaacaacaacaag
gaaaatgaacctatcaaagagacagagccccctgcctcacagggagaaccaggtaaaccc
caggcctcaggttatgctcctaaatcatttcacgtggaagacacccctgtttgtttctca
agaaacagttctctcagttctctcagcattgattctgaagatgacctgttgcaggaatgt
ataagttctgcaatgccgaaaaagaaaaagccttcaaggctcaagcctgataatgaaaag
catagtcctagaaatatgagtggcatattagcggaagatttgacactcgatttgaaagat
atacagagaccagattcagaacatggtttatccccagattcagaaaattttgattggaaa
gctattcaggaaggtgcaaattccatagtaagtagtttacatcaagctgctgctgctgca
tgtttatctcgacaagcttcatctgattcagattccatcctttcactgaaatcgggcatc
tctctgggatcaccatttcatcttacacctgatcaagaagaaaaaccctttatgaataat
aaaggcccacgaattctaaaacctggggagaaaagtacattggaaactaaaaaaatagaa
tctgaaaataaaggaataaaaggaggcaaaaaggtttataaaagtttgattactggaaaa
gttcgatctaattcggaaatttcgagccaaatgaaacaaccccttccaacaaacatgcct
tcaatctctcgaggtaggacaatgattcatattccaggagttcggaatagctcttcaagt
acaagcccagtttctaaaaaaggcccacccctcaagactccagcctccaaaagccctagt
gaaggtcagccagctaccacctctcccagaggaaccaagccatcagtgaagtcagaatta
agccctgttacaaggcaggcatcccagacagcggcatcaaacaaaggaccttctagatca
ggatctagagattccactccttcaagacccgcccagcaaccattaagtagaccaatgcag
tctccagggcgaaactcaatctctcctggtagaaatggaataagtccccctaacaaatta
tctcaactaccaaggacgtcatcccctagtactgcttcaactaagtcctcaggttctggg
aaaatgtcttacacatctcctggcagacagatgagccagcagaacctcaccaaacaaacg
ggcttatccaagaatggcagtggtatcccaaggagtgaatctgcctccaaagggctaaat
caaatgagtagtaataatggagccaataaaaaagtagaacttttcagaatgtcttcaaca
aagtcaagtggaagtgaatccgataggtcagagagacctgtattagtacgccaatcaact
ttcatcaaagaagctccaagcccaaccctaaggagaaaactggaggaatctgcttcattt
gagtctctttctccatcttctagacccgattctcccacacggtcccaggcacacactcca
gttttaagtccttcccttcctgatatgtctctacctacacattcgtctgttcagtctggt
ggatggcgaaaactcccacctaacctcagtcccaccatagagtacaacgatggaagacca
gtaaagcgccatgatatagcgcgctctcattccgaaagtccttccagacttcccatcaat
aggtcagggacctggaaacgtgagcacagcaaacactcatcatcacttcctcgagtaagc
acttggagaagaactggaagttcatcctcaattctttctgcttcatcagaatctagtgaa
aaggcaaaaagcgaggatgaaaaacaagtgaactctatttcaggaagcaaacaaactaaa
gaaaaccaggtatccacaaaaggaacatggagaaaaataaaagaaagtgaaatttctccc
acaaatagtacgtctcagaccacttcttcaggtgctgcaaatggtgctgaatcaaaaact
ctgatttatcaaatggcacctgctgtttctaaaacagaggatgtttgggtgagaattgag
gattgccccattaacaaccctagatctggaagatctccaacaggaaattctccccccgtg
attgacactgtttcagaaaagggaagcccgaaccctaaagattcaaaagataatcaggga
aaacaaaatgtgagcaatggtagtgcccctacacgcaccgtgggtctggaaaaccgcctg
aattcctttattcaggtagatcccccagaccaaaaaggaactgagacaaaaccgggacaa
agtaataaccctgtccctacatccgagactaatgaaagttctatagctgagcgtaccccg
tttagttctagcagctcaagcaagcacagttcaccaagtgggactgtcgccgccagggtg
agtccttttaattacaacccaagcccaaggaaaagcagcacagatggcacttccgcccga
ccgtctcagatcccgacgccagtgagtaacaacacaaagaaacgcgactcaaaacccgac
agcacggaacccagtgggactcaaagtccgaaacgccattccgggtcttaccttgtgaca
tctgtgtga

  All links  
Gene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (21)   
   RefSeq(pep) (21)   
DNA sequence (21)   
   RefSeq(nuc) (21)   
Protein domain (17)   
   Pfam (17)   
All databases (62)   

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