KEGG   Ovis canadensis (bighorn sheep): 138436199
Entry
138436199         CDS       T11679                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ocan  Ovis canadensis (bighorn sheep)
Pathway
ocan01522  Endocrine resistance
ocan04010  MAPK signaling pathway
ocan04015  Rap1 signaling pathway
ocan04068  FoxO signaling pathway
ocan04071  Sphingolipid signaling pathway
ocan04114  Oocyte meiosis
ocan04148  Efferocytosis
ocan04218  Cellular senescence
ocan04261  Adrenergic signaling in cardiomyocytes
ocan04370  VEGF signaling pathway
ocan04380  Osteoclast differentiation
ocan04517  IgSF CAM signaling
ocan04519  Cadherin signaling
ocan04550  Signaling pathways regulating pluripotency of stem cells
ocan04611  Platelet activation
ocan04613  Neutrophil extracellular trap formation
ocan04620  Toll-like receptor signaling pathway
ocan04621  NOD-like receptor signaling pathway
ocan04622  RIG-I-like receptor signaling pathway
ocan04625  C-type lectin receptor signaling pathway
ocan04657  IL-17 signaling pathway
ocan04658  Th1 and Th2 cell differentiation
ocan04659  Th17 cell differentiation
ocan04660  T cell receptor signaling pathway
ocan04664  Fc epsilon RI signaling pathway
ocan04668  TNF signaling pathway
ocan04670  Leukocyte transendothelial migration
ocan04714  Thermogenesis
ocan04722  Neurotrophin signaling pathway
ocan04723  Retrograde endocannabinoid signaling
ocan04728  Dopaminergic synapse
ocan04750  Inflammatory mediator regulation of TRP channels
ocan04912  GnRH signaling pathway
ocan04914  Progesterone-mediated oocyte maturation
ocan04917  Prolactin signaling pathway
ocan04926  Relaxin signaling pathway
ocan04932  Non-alcoholic fatty liver disease
ocan04933  AGE-RAGE signaling pathway in diabetic complications
ocan04935  Growth hormone synthesis, secretion and action
ocan04936  Alcoholic liver disease
ocan05014  Amyotrophic lateral sclerosis
ocan05020  Prion disease
ocan05022  Pathways of neurodegeneration - multiple diseases
ocan05132  Salmonella infection
ocan05133  Pertussis
ocan05135  Yersinia infection
ocan05140  Leishmaniasis
ocan05142  Chagas disease
ocan05145  Toxoplasmosis
ocan05152  Tuberculosis
ocan05161  Hepatitis B
ocan05163  Human cytomegalovirus infection
ocan05167  Kaposi sarcoma-associated herpesvirus infection
ocan05169  Epstein-Barr virus infection
ocan05170  Human immunodeficiency virus 1 infection
ocan05171  Coronavirus disease
ocan05205  Proteoglycans in cancer
ocan05208  Chemical carcinogenesis - reactive oxygen species
ocan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ocan05415  Diabetic cardiomyopathy
ocan05417  Lipid and atherosclerosis
ocan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    138436199 (MAPK11)
   04015 Rap1 signaling pathway
    138436199 (MAPK11)
   04370 VEGF signaling pathway
    138436199 (MAPK11)
   04668 TNF signaling pathway
    138436199 (MAPK11)
   04068 FoxO signaling pathway
    138436199 (MAPK11)
   04071 Sphingolipid signaling pathway
    138436199 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    138436199 (MAPK11)
   04519 Cadherin signaling
    138436199 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    138436199 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    138436199 (MAPK11)
   04218 Cellular senescence
    138436199 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    138436199 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    138436199 (MAPK11)
   04613 Neutrophil extracellular trap formation
    138436199 (MAPK11)
   04620 Toll-like receptor signaling pathway
    138436199 (MAPK11)
   04621 NOD-like receptor signaling pathway
    138436199 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    138436199 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    138436199 (MAPK11)
   04660 T cell receptor signaling pathway
    138436199 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    138436199 (MAPK11)
   04659 Th17 cell differentiation
    138436199 (MAPK11)
   04657 IL-17 signaling pathway
    138436199 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    138436199 (MAPK11)
   04670 Leukocyte transendothelial migration
    138436199 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    138436199 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    138436199 (MAPK11)
   04917 Prolactin signaling pathway
    138436199 (MAPK11)
   04926 Relaxin signaling pathway
    138436199 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    138436199 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    138436199 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    138436199 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    138436199 (MAPK11)
   04722 Neurotrophin signaling pathway
    138436199 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    138436199 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    138436199 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    138436199 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    138436199 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    138436199 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    138436199 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    138436199 (MAPK11)
   05161 Hepatitis B
    138436199 (MAPK11)
   05171 Coronavirus disease
    138436199 (MAPK11)
   05163 Human cytomegalovirus infection
    138436199 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    138436199 (MAPK11)
   05169 Epstein-Barr virus infection
    138436199 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    138436199 (MAPK11)
   05135 Yersinia infection
    138436199 (MAPK11)
   05133 Pertussis
    138436199 (MAPK11)
   05152 Tuberculosis
    138436199 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    138436199 (MAPK11)
   05140 Leishmaniasis
    138436199 (MAPK11)
   05142 Chagas disease
    138436199 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    138436199 (MAPK11)
   05020 Prion disease
    138436199 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    138436199 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    138436199 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    138436199 (MAPK11)
   05415 Diabetic cardiomyopathy
    138436199 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    138436199 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    138436199 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    138436199 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    138436199 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocan01001]
    138436199 (MAPK11)
Enzymes [BR:ocan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     138436199 (MAPK11)
Protein kinases [BR:ocan01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   138436199 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 138436199
NCBI-ProteinID: XP_069437931
Position
3:complement(231376137..231384359)
AA seq 393 aa
MRGGQSSSPGQGTRPHMPQLGPSTAKQIFKKKKTPGGRGEPGSEWGLMPVLVAFWPVTEA
GPDARSCSSAYDTRLRQRVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFT
PATSLEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDL
KPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYSQTVDIWSVGC
IMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLR
SIFRGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKE
RTVEEWKELTYQEVVSFKPPEPPQPLGSLDVEQ
NT seq 1182 nt   +upstreamnt  +downstreamnt
atgcggggaggccagagttcaagccctggtcaggggactagaccccacatgcctcaacta
ggacctagcacagccaaacaaatatttaaaaaaaagaagaccccaggagggaggggagag
cctgggagcgagtggggtctcatgcctgtgctggtggccttctggccagtgaccgaggca
gggcctgacgcgcggtcttgcagctcagcctacgacacacggctgcgccagagggtggcg
gtgaagaagctgtcgcggcccttccagtctctgatccacgcgcggaggacctaccgggag
ctgcggctgctcaaacacctgaagcacgagaacgtcatcgggctgctggacgtgttcacg
ccggccacctccctcgaggatttcagcgaagtgtacctggtgaccacgctgatgggcgcc
gacctgaacaacatcgtcaagtgccaggcgctgagtgacgagcacgtccagttcctcgtg
taccagctgctgcgcgggctaaagtacatccactcggccgggatcatccaccgggacctg
aagcccagcaacgtggccgtgaacgaggactgcgagctgcggatcctggacttcggactg
gcgcgccaggcagacgaggagatgactggctacgtggccacgcggtggtacagggccccc
gagatcatgctaaactggatgcactacagccagacagtggacatctggtccgtgggctgc
atcatggctgagctgctccagggaaaggctctcttccccggaagtgactacatcgaccag
ctgaagcgtatcatggaggtggtgggcacacccagccctgaggttctagcaaagatatcc
tcagaacatgcccggacctacatccagtccctgccccccatgccccagaaggacctcagg
agcatcttccgcggagccaaccccctggctgtggacctcctgggcaggatgctggtgctg
gacagtgaccagagggtcagcgcggccgaggccctggcacatgcttacttcagccagtac
cacgacccggaggacgagccagaggcggagccctatgacgagagcgtggaggccaaggag
cgcacggtggaggagtggaaggagctcacctaccaggaagtcgtcagcttcaagcccccg
gagcccccgcagccactgggcagcctggacgtcgagcagtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (7)   
   Pfam (7)   
All databases (17)   

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