KEGG   Oryzias latipes (Japanese medaka): 100049465
Entry
100049465         CDS       T02443                                 
Symbol
plcb2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ola  Oryzias latipes (Japanese medaka)
Pathway
ola00562  Inositol phosphate metabolism
ola01100  Metabolic pathways
ola04020  Calcium signaling pathway
ola04070  Phosphatidylinositol signaling system
ola04081  Hormone signaling
ola04082  Neuroactive ligand signaling
ola04261  Adrenergic signaling in cardiomyocytes
ola04270  Vascular smooth muscle contraction
ola04310  Wnt signaling pathway
ola04371  Apelin signaling pathway
ola04540  Gap junction
ola04621  NOD-like receptor signaling pathway
ola04912  GnRH signaling pathway
ola04916  Melanogenesis
Module
ola_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ola00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100049465 (plcb2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    100049465 (plcb2)
   04371 Apelin signaling pathway
    100049465 (plcb2)
   04020 Calcium signaling pathway
    100049465 (plcb2)
   04070 Phosphatidylinositol signaling system
    100049465 (plcb2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100049465 (plcb2)
   04081 Hormone signaling
    100049465 (plcb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    100049465 (plcb2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    100049465 (plcb2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100049465 (plcb2)
   04916 Melanogenesis
    100049465 (plcb2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100049465 (plcb2)
   04270 Vascular smooth muscle contraction
    100049465 (plcb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ola04131]
    100049465 (plcb2)
Enzymes [BR:ola01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100049465 (plcb2)
Membrane trafficking [BR:ola04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100049465 (plcb2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100049465 (plcb2)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLC-beta_C PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 100049465
NCBI-ProteinID: NP_001265769
UniProt: Q08JX0
Position
22:complement(14871981..14887128)
AA seq 1248 aa
MNKKRYFLDPPEVKDYLVKGERFTKWSEDSTKTVPVTMKMDPKGFYVYWMNQSKETTFLD
VNTIRDTRTGKYAKLPKHPKVRNVFNLDFPDSNHLAKTLTIVSGPDMVNLTYHNFFASKD
KVTQNWANDILAISYNAARNNACRQVYLEKIYVRISLQTNKDGKIPVKNIYKMFPADKKR
VESALAAAHLPKGKYDSMKADVFTEAAFRTFMMNLCPRPEIYEIFTSYSTKPTMSKENFT
KFLYEKQRDSRLNEELFPRLRQDQIKALIDKYEPISTNSNRGFISPEGLLFFLMGPETSV
VMQDKLAKSQDMTQPLPHYFIKSSHNTYLTAGQFSGVSSPEMYRQCLLSGCRCLELDCWK
GKPPDEEPIITHGFTMTTEILFKDVIEAIAESAFKTSKYPVILSFENHVDSVKQQEKMAN
YCKTLFGDALLTEPLDKYPLKPGQQIPSPSELMGKILIKNKKGSHEKPAQAKKSSTAATD
QAAAATPQDPNCPSQDETNPTSPSQENQADGEGTVEENEEQEDTEEQDEEKMKTSDEGTA
GQEVTAYEAMSSIVNYIQPNKFISFDNARKKNKSYVISSFVETKGEAMISKTAVEFVEYN
KRQMSRIYPKGTRMDSSNYSPQPFWNVGCQMVALNYQTMDFPMQLNMALFEFNGRTGYLL
KHDVLRRGDKKFDPFCDRIDTVVASTLTIKIYSGQFLSDKNVKTGVEVEVIGLPGDPKKK
YRTKWSTTPNAINPVWNEEPFVFEKILLPELASLRIVVHEENGKFLGHRIIPVDAIQSGF
HHICLRSESNMPLTLPALFVYIEVKDYIPAAFADFTDALFNPTKGTEKTTKTPKESSTDY
ISPYELPLVVQPPTDKVKESAAPAAEKLTSEKTPSTDAADQSAQAAHESCPGAADPPQPD
PPSTPTEDAGGPSSEVPSEDASSPKKAVEEKEAAQKPVAVLDAQDQPDTQSEPVVEQVVS
DSCRRSEEPASAEPKSEETTPPAEAAGAGDNSQTEPSTVTTEHLTQHKNYLKVIKRQERE
MKEFEKKYQKKEEELMQKYSDVFKAVKKKVSLKKKEGDDDTSDSSVKASRVQEQREKMQA
ELQVLWTEQCDQLKKKKEQCATERLAKLMEMAMEKHTSELKALESETKEKKKTVSKCSST
EKPKLKKAMSTEVLDDTSQSEGVQSSESFPQQEALMRKQEATLEEIKTLTNQLNQEAVKE
HTQKLRSLPAEVKEAVNSCMGAHFPELVDKPGEKRVGEMGFYGDVFLG
NT seq 3747 nt   +upstreamnt  +downstreamnt
atgaataagaaaaggtactttctggaccctccagaggtcaaagactatttggtcaaagga
gaaagatttaccaagtggtcagaggattcgacaaagactgttccggtgacgatgaagatg
gatccaaaagggttctatgtgtactggatgaaccaaagcaaggagacaacattcctggac
gttaacacaatcagagataccagaacaggaaaatatgccaaacttcccaagcatccaaaa
gtccgtaatgtgttcaacctggattttcctgacagcaaccaccttgccaaaaccttgacc
atcgtttcaggtccagacatggtgaatctgacatatcacaacttctttgcctcaaaagac
aaagtgacacagaactgggcgaacgatattcttgcgatttcttataatgctgcaagaaac
aatgcatgcagacaagtctatttggagaaaatatacgtccgcatttccctccaaaccaac
aaggatggcaagattccagtgaagaacatttacaagatgtttcctgccgacaagaaaagg
gtggaaagtgccttagctgcagcacacctcccaaagggaaagtatgactctatgaaagcg
gatgtgttcactgaagcagccttcaggaccttcatgatgaatctgtgtcctcggcctgaa
atctatgagattttcacttcttactccaccaaacccacaatgagcaaggagaacttcacc
aagttcctctatgagaagcagagggactcccggctcaatgaggagctgtttccacgtctg
cgacaagaccagatcaaggctttgattgacaagtatgagcccatctctacgaattcaaac
agaggctttatttctccagaaggtcttttgttcttcctgatgggtcctgagacatcagtc
gtcatgcaagacaagctagcaaagagtcaggatatgacccaacccctaccccattacttc
atcaagtcttcccataacacttatctaacagctggtcagttttcaggcgtgtcctctcct
gagatgtaccgtcagtgtcttctgtctggatgtcggtgtctggagctggactgctggaag
ggaaaacctccagatgaagagcccatcatcacccatggcttcaccatgaccactgagatt
ctcttcaaggacgtgattgaagctattgcagagagtgccttcaagacctccaaatacccg
gtcatcctctcgtttgagaaccacgtggactcggttaaacagcaagaaaagatggccaac
tactgcaaaaccctatttggagatgccttgctcacagagcctttggacaaatatcctctg
aagccaggccagcagatccccagcccctctgagctcatggggaagatcctcattaagaac
aagaagggttctcatgaaaaaccagcccaggcgaagaaaagcagcacagcagccaccgat
caggcagcagctgcaaccccccaagatccaaactgtccctcccaggatgaaactaaccca
acatctcccagtcaggagaaccaagctgatggagaaggaactgtggaggaaaatgaggag
caagaagatacagaagaacaagatgaagagaagatgaagacatctgatgagggcacagca
ggacaagaagttacagcttacgaggcaatgtcatccatcgtcaactacattcagccaaac
aaattcatctctttcgacaatgccagaaagaaaaataagagttacgtcatctcatccttt
gtggaaaccaaaggggaagcaatgatttccaagactgcagttgaatttgtcgaatacaat
aagaggcagatgagcaggatttatcccaaaggaaccagaatggactcatccaactactcc
cctcaacctttttggaacgttggctgccagatggtggcactcaactaccaaaccatggat
ttccccatgcagctgaacatggctctgtttgaattcaacggcaggacgggttacctgctc
aagcacgacgtcctgcgtcgtggagacaagaagtttgaccctttttgcgacaggattgac
acagtcgtggccagcaccctcaccatcaagatatactcaggacagtttctgtcagataag
aatgtgaaaactggagtggaagtggaagttatcggactccccggtgaccccaagaaaaag
tatcgcaccaagtggtccaccacacccaacgccattaaccctgtctggaatgaggagcct
tttgtttttgagaagattttgcttccagaattggcctctttaagaattgtggtccatgaa
gaaaatgggaagtttctgggacacagaattattcccgtcgatgccatccagtcaggtttc
catcacatctgtctgcgcagcgagagcaacatgcctctcactctgcctgctctttttgtg
tacattgaggttaaggactacatccctgctgcctttgcagatttcacagatgccttattt
aatccaacaaaaggcacagagaagaccacaaagacccccaaagagtcatctactgactac
atttctccgtatgagttgcctcttgtcgtccaacctcccacagataaagtcaaggaaagt
gcagcccctgcagcagaaaagctcacatctgaaaagacgccgtctactgatgctgctgac
cagtcagcccaggcggcccatgaatcctgtccaggggcagcagatcctccacaacctgat
cctccttcaactcctactgaggatgcaggaggcccctcatctgaagtcccttcagaggat
gcttcttccccgaagaaggcagtcgaggagaaagaagctgcccaaaagcctgtggcagtt
cttgatgcacaagaccagcccgatacacaatcagaacctgttgtagagcaggtggtatcg
gactcctgcaggcgttctgaagaacctgcctctgctgagcccaaatctgaagaaacaacc
cccccagctgaggcagcgggagcaggggacaactctcagacagagccttcaactgtgact
actgagcacctgacacagcacaaaaactatctgaaggtcatcaagcgtcaggagcgggag
atgaaagagtttgaaaagaagtatcagaaaaaagaagaggagctgatgcagaaatactca
gacgtcttcaaggctgtcaaaaagaaagtttctttaaagaaaaaagaaggagacgacgac
acctctgacagcagcgtgaaggcgtcacgggtgcaggagcagagggaaaagatgcaggcc
gagctgcaggttctgtggacagagcagtgtgatcagctgaagaagaagaaggagcagtgt
gccacagagagacttgctaaactgatggagatggccatggagaagcacaccagtgagctg
aaggctttggaaagtgaaaccaaagagaaaaagaaaacggtctccaagtgttcatccaca
gaaaaaccaaagctgaaaaaagcgatgagcactgaggtactagacgacaccagtcaatcg
gaaggagtacagtcttcagagtcctttccacaacaagaagctctgatgaggaaacaagag
gccacactggaagaaatcaagaccttgacgaatcagctcaatcaagaggcggtaaaggag
catactcaaaagctgaggtctttgccagcagaggttaaagaggcagtaaacagctgcatg
ggggcgcacttccctgaacttgtggacaagcctggagagaagagagttggagaaatgggc
ttttatggagatgttttcttgggttaa

  All links  
Gene (29)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (7)   
   Pfam (7)   
All databases (45)   

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