KEGG   Prionailurus bengalensis (leopard cat): 122488602
Entry
122488602         CDS       T07574                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg04310  Wnt signaling pathway
pbg04390  Hippo signaling pathway
pbg04519  Cadherin signaling
pbg04550  Signaling pathways regulating pluripotency of stem cells
pbg04810  Regulation of actin cytoskeleton
pbg04934  Cushing syndrome
pbg05010  Alzheimer disease
pbg05022  Pathways of neurodegeneration - multiple diseases
pbg05165  Human papillomavirus infection
pbg05200  Pathways in cancer
pbg05206  MicroRNAs in cancer
pbg05210  Colorectal cancer
pbg05213  Endometrial cancer
pbg05217  Basal cell carcinoma
pbg05224  Breast cancer
pbg05225  Hepatocellular carcinoma
pbg05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    122488602 (APC2)
   04390 Hippo signaling pathway
    122488602 (APC2)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    122488602 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    122488602 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122488602 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122488602 (APC2)
   05206 MicroRNAs in cancer
    122488602 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122488602 (APC2)
   05225 Hepatocellular carcinoma
    122488602 (APC2)
   05226 Gastric cancer
    122488602 (APC2)
   05217 Basal cell carcinoma
    122488602 (APC2)
   05213 Endometrial cancer
    122488602 (APC2)
   05224 Breast cancer
    122488602 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    122488602 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122488602 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    122488602 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    122488602 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pbg01009]
    122488602 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pbg03036]
    122488602 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:pbg04812]
    122488602 (APC2)
Protein phosphatases and associated proteins [BR:pbg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     122488602 (APC2)
Chromosome and associated proteins [BR:pbg03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    122488602 (APC2)
Cytoskeleton proteins [BR:pbg04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     122488602 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Arm Suppressor_APC Arm_APC_u3 APC_r SAMP ARM_PUB ZER1-like_2nd SSNA1 Wtap PEA2_C bZIP_1 MPS2 PDC10_C Par-4_C HALZ Sec7-like_HUS CCDC138_cc
Other DBs
NCBI-GeneID: 122488602
NCBI-ProteinID: XP_043446077
Position
A2:826246..849721
AA seq 2282 aa
MGLLGLLSLLHSAFFGDQALQELKMTSSVAPYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKHLQGKLEQEAGVLVSLGQTEVLEQLKALQMDITSLYNLKFQPPAL
GPEPTGRTPEGSPVHGSGPSKDSFGELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDQELLSAQDRVQQTEPQALLAVKSVPVDEDPETEVPTHPEDGVPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGTEAGAGGRDGSPG
ATGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGAEG
GGASGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHRMTRDP
LNLALRRYAGMTLTNLTFGDVANKAALCARRGCMEAIVAQLASESEELHQVVSSILRNLS
WRADIHSKKVLREVGSMTALMRCVLRASKESTLKSVLSALWNLSAHSTENKAAICQVDGA
LGFLVRTLTYKCQSNSLAVIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTSH
SLTIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAH
RPAKYQATATAVSPGACAPSLYVRKQRALEAELDTRHLAQALDHLEKQGLPEAEAEAASK
KPLPPLRHLDGLARDYASDSGCFDDDEAPSLAAAASTAEPASPAVLSLFLGSPFLQGQAL
ARAPPARRSGPEVEKEAGGEAAVAARAKAKLALAVARIDRLVEDISALHTSSDDSFSLSS
GDPGQEAPREGRAQSCSPCRRPEGRRREAGGRAHPLLRLQAAHASLSNDSLNSGSSAGDG
RCPREHTRPCPLAVLAEHHEGAPCSQARPSRLDLSLPGGREPAGRDGPAADACVRTIKLS
PTYQHVPLFEGHPRAGAGAGPPAAGARKQAWLPTEGLSQLPEKPAAEPAPLRLSRCSSLS
SLSSAGRPGPSEAGDLDSDSSLEALEEAGPGKADLDGAWLGPGAASLPVAIPAPHRGCGL
GAEDTTPSSSSENCVQETPLVLSRCSSVSSLSSFESPSIASSVPSDPCSGLGSGTVSPSE
LPDSPGQTMPPSRSKTPPLAPAPPGERESTQFSLQWESYVKRFLDIADRRERCRLPSELD
AGSVRFTVEKPDENFSCASSLSALALHEHYVQKDVELRLLPPAGPDRGGGPHLAGHRRRD
EAAGCLEGPAAADQELRLLRECLGAAVPARLRKVASALVPGRRALPVPVYMLVPAPARGD
DSCTDSAEGTPVTFSSATSLSDETLQGPPRDPPAGQAAGRKSVGREAAARQATGHRHGAW
GGGRSAEQARGAGTSRAGLELPLRQPSSACTDGDGPRPGQARGDGAPQSLCLTTPTEEAV
YCFYDNDSDEEPSEAVAPPRRASAIPRAVKREHPAGRKDAQATPKAAAKALPAARAQPSL
IADETPPCYSLSSSASSLSEPEPPERPAGRPRAPEPAVAKVVGPGGGCNGAPSPRAGTGP
GPLRRCVGSAVPGRRLQASGPRRRKPQAARPDKRPAERPQERGDEAAGSDQASDLDSVEW
RAIQEGANSIVTWLHQAAAAATHEASSGSDSILSESGLSGSTLQPPVHRKGQRLQAGGAA
RPRPEKRDSTLAQHGPSGPEKLRGAQKTACRVPAVLRGRTVIYVPSPAPRAQPRGNPGTR
VAPRKVGAPAQPAAPAKAPSPGQQQQQQQQQQQQRSRSLHRPGKISELAALSPPQRSATP
PARLAKAPSSGSSPASPASQPPPRRPPSGPQAAGPLPGPGASLAPQTPARALLSKQHKTQ
KSPVRIPFMQRPARRGPPALARAAPEPGPRGRAGAEGSPGARGGRLGLVRVASARSSGSE
SSDRSGFRRQLTFVKESAGLPRRRRSEVAAPEAAPSASQGGSPRRGRPALPAVFLCSSRC
DELRAAPRRPPAARPSPGERPARRPSSESPSRLPVRTPVARPEAVKRYASLPHISALPGP
AADAARRSSDGEARPLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLVGASPEEGPGG
PPQRKTSDAVVQTEDFVAAKTNSSTSPSLESRGPPQALGGGPASFPGSDVDGPCPPKAPT
SASFVHEGLGVAVGGFPTSRHGSPSRAARVPPFNYVPSPMVAAAADLAAEKAPTAAPDSL
LE
NT seq 6849 nt   +upstreamnt  +downstreamnt
atggggctcttggggctgctgagcctgctgcactcagccttcttcggggaccaggcgctg
caggagctgaagatgacgagctccgtggcgccctacgagcagctggtgcggcaggtggag
gccttgaaggccgagaacagtcacctgaggcaggagctgcgagacaactcgagccacctg
tccaagctagagacggagacgtccggcatgaaggaggtcctgaagcacttacaaggcaag
ctggagcaggaggccggagtgctggtgtccttggggcagacggaggtgctggaacagctg
aaagccctgcagatggacatcaccagcctgtacaacctcaagttccagcccccagcccta
ggtcctgagcccactggccggacccccgaaggaagtccagtacacggctccgggccttcc
aaggacagctttggggagctgagccgggcgaccatccggctgctggaggaactggaccgg
gagaggtgcttcctgttgaacgagatcgagaaggaggagaaggagaagctctggtattac
tcacagctgcagggcctgtccaagcgcctggacgagctcccgcacgtggagacgcagttc
tcgatgcagatggacctgatccggcagcagctggagttcgaggcccagcacatccgctcg
ctgatggaagaacgcttcggcacctcggacgagatggtgcagcgcgcgcagatccgcgct
tctcgcttggagcaaatcgatcaggagctgctgtccgcacaggaccgggtgcaacagaca
gagccccaggccctgctggcggtgaagtcggtgccggtggacgaggatccagagactgaa
gtccccacacacccggaggatggtgtccctcagcccggcaacagcaaggtggaggtggtc
ttctggctgctgtccatgctggcaacgcgtgaccaggaggacacggcgcgcaccctgctg
gccatgtccagctcgccggagagctgcgtggccatgcgccgctcggggtgcctgccgctg
ctgctgcagatcctgcacggcaccgaggccggcgctgggggtcgcgacggaagccccggg
gcgacgggcgccaaggacgcacgcatgcgcgccaacgcggcgctgcacaacatcgtcttc
tcgcaacctgaccagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcag
atccgggcctattgtgagacctgctgggactggctgcaggccagggacggcgccgaggga
ggcggcgccagcggcgctcccgtccccatcgagccccagatctgccaggccacctgtgcc
gtgatgaagctgtcttttgacgaggaataccgccgagccatgaacgagctgggtgggctg
caggccgtggcagagttactgcaagttgactacgagatgcacagaatgacccgggacccg
ctgaacctcgccctccgtcgatacgccggcatgaccctcaccaacctcacctttggagac
gtggccaacaaggccgcactgtgtgcccgccggggctgcatggaggccatcgtggcccag
ctggcttctgagagcgaggagctgcaccaggttgtgtccagcatcctgcgcaacctgtcc
tggcgggccgacatccacagcaagaaggtgctgcgggaggtgggcagcatgaccgccctg
atgcggtgcgtccttcgagcctccaaggagtccaccctgaagagtgtgctcagcgccctg
tggaacctgtcggcgcacagcacggagaacaaggcggccatctgccaggtggacggcgcc
ctgggcttcctggtgaggacactgacctacaagtgccagagcaactcgctggccgtcatc
gagagtggcggcggcatcctgcgcaacgtgtccagcctcatcgccacgcgggaggactac
aggcaggtgctgcgggaccacaactgtctgcagacgctgctgcagcacctgacgtcccac
agcctgaccatcgtgagcaacgcgtgcggcacgctctggaacctgtcggcccgcagcccg
cgcgaccaggagctgctgtgggacctgggggccgtgggcatgctgcggaacctggtgcac
tccaagcacaagatgatcgccatgggcagcgccgcggccctgcgcaacctgctggcccac
cggcccgccaagtaccaggcgacggccaccgccgtgtcccccggcgcgtgcgcacccagt
ctgtacgtgaggaagcagcgggcgctggaggccgagctggacacgcgacatctggcccag
gcgctcgaccacctggagaagcagggcctgcccgaggccgaggccgaggccgcctccaag
aagccactgccgcccctgcggcacctggacgggctggcccgggactacgcctccgactcc
ggctgcttcgacgacgacgaggcgccctccctggccgccgccgcctcgaccgccgagccc
gccagccccgccgtgctgtccctcttcctgggcagccccttcctgcagggacaggctctg
gcccgcgccccgcccgcccgccgcagcggcccggaggtggagaaggaggccggcggcgag
gcggccgtggcggccagggccaaggccaagctggcgctggcggtggcgcggatcgaccgg
ctggtggaggacatctcagccctgcacacctcgtccgacgacagcttcagcctcagctcc
ggggaccccgggcaggaggccccgcgggagggccgcgcccagtcctgctccccttgccgg
cggccggagggcaggcggcgggaggccggcggccgggcccacccgctgctgcggctccag
gccgcccacgccagcctgtccaacgacagcctcaacagcggcagcagcgccggcgacggg
cgctgcccccgcgagcacacgaggccctgcccgctggccgtgctggccgagcaccacgag
ggggccccgtgcagccaggcgcggcccagccggctggacctcagcctgccgggcggccgg
gagccggccgggagggacggccccgcggccgacgcctgcgtgcgcaccatcaagctctcg
cccacctaccagcacgtgccgctcttcgagggccaccccagggcgggggcgggcgcgggg
cccccggccgccggggcccggaagcaggcctggctgcccacggagggcctgagccagctg
cccgagaagccggcggcagagccggcgcccctccgcctgtcccgctgcagctctctgtcc
tcgctgtcctcggccggccgccccggccccagtgaggccggggacctggacagcgactcg
tccctggaggcgctggaggaggcggggcccggcaaggcggacctggacggagcctggctc
gggcccggggccgcctccctgcccgtggccatcccggcgccgcaccggggctgcggcctg
ggggcggaggacaccacgccgtccagctcctccgagaactgcgtgcaggagacgccgctg
gtgctgagccgctgcagctccgtgagctccctgagcagtttcgagagcccgtccatcgcc
agctccgtccccagcgacccgtgcagcgggctgggcagcggcacggtcagccccagcgag
ctgcccgacagccccgggcagaccatgccgcccagccgcagcaagacgcccccgctggcc
cctgcgccccccggcgagcgcgagagcacccagttcagcttgcagtgggagagctacgtg
aagcgattcctggacatcgccgaccgccgggagcgctgccggctgccgtcggagctcgac
gccggcagcgtccgcttcacggtggagaagccggatgagaacttctcgtgcgcctcgagc
ctcagcgcgctggccctgcacgagcactacgtgcagaaggatgtggagctgcggctgctg
ccccccgccggcccggatcgcggcggcggcccgcacctcgcggggcaccgccggcgggac
gaggccgctgggtgcctggaggggccggcagccgccgaccaggagctgcggctgctgcgc
gagtgcctgggggcagccgtgcccgcccggctccgcaaggtggcctcggccctggtgccc
ggccgccgcgcgctgcccgtgcccgtgtacatgctggtgcccgcccccgcccggggggac
gactcatgcaccgactcagccgagggcacgccggtcaccttctccagtgccacctcgctc
agcgacgagacgctgcagggacctcccagggacccacccgccgggcaggcggccggccgg
aagtctgtgggtcgggaggccgccgccaggcaggccaccgggcaccgccacggggcgtgg
ggcgggggccggagcgcagagcaggcccggggggcgggcacgagccgggcggggctggag
ctgcccctccgccagccctcgagcgcctgcacggacggggacggcccccgcccgggccag
gcacgtggggacggggcaccgcagtcgctgtgcctcacgacgcccaccgaagaggccgtg
tactgcttctatgacaacgactccgatgaagagccgtccgaggcggtggcgcccccgcgg
cgggcgtccgccatcccccgtgccgtgaagagagagcacccggccggcaggaaggacgca
caggccacacccaaggccgcggccaaggccctgcccgctgcccgcgcccagcccagcctc
atcgccgacgagaccccgccatgctattccctgagctcctccgccagctccctcagcgag
cctgagccccctgagcggccggccggccggccccgcgctcccgagccggccgtcgccaaa
gtcgtgggcccggggggcgggtgcaatggcgcccccagcccgcgggcggggacggggccg
gggccgctccggcgctgtgtcgggtcagccgtgcccgggcgccggctccaggcgtcaggc
ccgcggcgccgcaagccccaggctgcccggccagacaagcggccagcggagcggccccag
gagcgcggtgacgaggcggcgggctcagaccaggcctccgacctggacagcgtcgagtgg
cgcgccatccaagagggcgccaactccatcgtcacgtggctgcaccaggcggcggccgcg
gccacccacgaggcctcatctggctctgactccatcctgtcggaatccgggctgtcgggc
tccaccctgcagccgccggtgcacaggaagggacagcggctgcaggcgggcggtgccgcg
aggccgaggccggagaagcgggactcaaccctggcccagcacggccccagtggccccgag
aagctgcgcggtgctcagaagacggcgtgcagggtgccggccgtgctccggggacggacc
gtgatctatgtgcccagcccggccccccgggcacagcccagaggcaaccccggcacccgt
gtggcaccgaggaaggtgggagcccctgcgcagcccgcagccccggccaaagcccccagc
cccgggcagcagcagcagcagcagcaacagcagcagcagcagcggtctcgaagcctacac
cggccgggcaagatctccgagctggcggcactgagccccccccagcggagcgccacgccg
cccgcccgcctggcgaaggccccctcgtccggctcctccccggcctccccggcctcccag
cccccgcccaggaggccgccctcgggcccccaggctgcggggcccctacctggtcccggg
gcgtctctggcgccccagacgcccgcgcgggccctactgtccaagcagcacaagacgcag
aagtcacccgtgcggatccccttcatgcagaggcccgccaggcgggggccgccagccctg
gcccgggcagccccggagccgggccccaggggccgggcaggagccgagggaagcccgggc
gcccgagggggccgcctgggcctggtgcgcgtggcctctgcccgctccagtggcagcgag
tcctccgaccgctcgggtttccggcggcagctgaccttcgtcaaggagtccgcgggcctg
ccgcgccgccgccgctcagaggtggccgcgcccgaggccgcgccctccgcctcccagggc
ggctccccccggcgcggtcggcccgccctgcccgcggtcttcctgtgctcctcgcgctgc
gacgagctgcgggcggccccccgacggccccctgcagccaggcccagccccggcgagcgg
ccggcgcggcgccccagctccgaaagcccgtcccgcctgcccgtccgcacgccggttgcc
cggcccgaggccgtcaagcgctacgcctccctgcctcacatcagcgcgctgccggggccc
gcggccgacgccgcccgccgcagcagcgacggggaggcccggccgctcccgagggtggcg
gccccgggcaccacgtggcgtcgcatccgggacgaggacgttccgcacatccttcggagc
acgctacccgccaccgccctgcccctggtgggcgcctcccccgaggagggccccggcggg
cccccgcagcgcaagaccagcgacgccgtggtccagaccgaggacttcgttgccgccaag
accaactccagcacgtctccgagcctggagagcagggggcccccccaggccctgggcggc
ggccccgcatccttccctggcagcgatgtggatgggccctgcccccccaaggcgcccacc
tctgcctccttcgtccatgagggcctgggggtggccgtgggaggctttcccaccagccgg
cacggctcccccagccgcgcggcccgcgtgcctcccttcaactatgtgcccagccccatg
gtggcagccgccgccgacttggccgcagagaaagcccccaccgctgcccccgacagcctt
ctggaatag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (20)   
   Pfam (20)   
All databases (28)   

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