KEGG   Prionailurus bengalensis (leopard cat): 122491978
Entry
122491978         CDS       T07574                                 
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg04310  Wnt signaling pathway
pbg04390  Hippo signaling pathway
pbg04519  Cadherin signaling
pbg04550  Signaling pathways regulating pluripotency of stem cells
pbg04810  Regulation of actin cytoskeleton
pbg04934  Cushing syndrome
pbg05010  Alzheimer disease
pbg05022  Pathways of neurodegeneration - multiple diseases
pbg05165  Human papillomavirus infection
pbg05200  Pathways in cancer
pbg05206  MicroRNAs in cancer
pbg05210  Colorectal cancer
pbg05213  Endometrial cancer
pbg05217  Basal cell carcinoma
pbg05224  Breast cancer
pbg05225  Hepatocellular carcinoma
pbg05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    122491978 (APC)
   04390 Hippo signaling pathway
    122491978 (APC)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    122491978 (APC)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    122491978 (APC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122491978 (APC)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122491978 (APC)
   05206 MicroRNAs in cancer
    122491978 (APC)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122491978 (APC)
   05225 Hepatocellular carcinoma
    122491978 (APC)
   05226 Gastric cancer
    122491978 (APC)
   05217 Basal cell carcinoma
    122491978 (APC)
   05213 Endometrial cancer
    122491978 (APC)
   05224 Breast cancer
    122491978 (APC)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    122491978 (APC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122491978 (APC)
   05022 Pathways of neurodegeneration - multiple diseases
    122491978 (APC)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    122491978 (APC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pbg01009]
    122491978 (APC)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pbg03036]
    122491978 (APC)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:pbg04812]
    122491978 (APC)
Protein phosphatases and associated proteins [BR:pbg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     122491978 (APC)
Chromosome and associated proteins [BR:pbg03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    122491978 (APC)
Cytoskeleton proteins [BR:pbg04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     122491978 (APC)
SSDB
Motif
Pfam: Arm_APC_u3 APC_basic EB1_binding APC_r APC_u5 APC_u14 APC_rep APC_u15 APC_u9 SAMP Arm APC_u13 APC_15aa Suppressor_APC ARM_ARMC5 ZER1-like_2nd Sec7-like_HUS
Other DBs
NCBI-GeneID: 122491978
NCBI-ProteinID: XP_043451322
Position
A1:173088487..173238006
AA seq 2877 aa
MYACLGSGPVAVLPASAPPSTLGSWSSGGGGGGGGGRVPQERKRPGGVRTSGRGADVWQE
VLKQLQGSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSR
SGECSPVPMGSFPKRGFVNGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLT
KRIDSLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRVTRIQQIEK
DILRIRQLLQSQATEAERSSQSKHEASSHEAERQNEGQGVAEINMATPGSGQGSAARMDH
ETASVLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCIS
MRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRV
LHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAM
NELGRKATRGISSQELGQGLAGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNL
TFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGS
VKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNT
LAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLS
ARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSS
LPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKPNLYGDYVFDTNRHDD
NRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGISLGNYHPATE
NPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTGELHCGTDERNALRRSSTA
HTHANTYNFTKSENSNRTCPMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSE
DDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNER
WARPKHIIEDEIKQSEQRQSRSQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGAN
GSETNRVSSNHGINQNVNQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNE
EKHHVDQPIDYSLKYATDIPASQKPPFSFSKSSSGQSTKTEHISSSSENTSTPSSNAKRQ
NQHHPSSTQSRNGQTPKATSCKVPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIG
CDQTTQETDSANTLQIAEIKENSGTRSTEESVSEVPTVSQHIRTKSSRLQASGLSAESTR
HKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSE
PCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPPQTVQSKREVPKNKAPTAEKRESGP
KQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPP
VQENDNGNETESEQPEEANESQVKEAEKPTDSEKDLLDDSDDDDIEILEECIISAMPTKS
SRKAKKPAQTAPKLPPPVARKPSQLPVYKLLPSQNRLQAQKHVSFTPGDDMPRVYCVEGT
PINFSTATSLSDLTIESPPNELAAGEGVRAGAQSGEFEKRDTIPTEGRSTDEAQRVKTSS
ATISELDDNKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASMSSSGANKNQLDG
KKKKPTSPVKPIPQNTEYRTRVRKNTDSKNNLNAERTFSDNKDSKKQNLKNNSKDFNDKL
PNNEDRVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKEN
KESEAKVTSHTELTSSQQSANKTQAVTKHPINRGQSKPMLQKQSTFPQSSKDIPDRGAAT
DEKLQNFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKETEPPDSQGEPSKPQASG
YAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPR
NMSGILAEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSR
QASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESENK
GIKGGKKVYRSLITGKVRSNSEISSQMKQPLQTNMPSISRGRTMIHIPGVRNSSSSTSPV
SKKGPPLKTPASKSPSEGQPATTSPRGTKPSVKSELSPVTRQTSQPAGANKGSSRSGSRD
STPSRPAQQPLSRPMQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSY
TSPGRQMSQQNLTKQTGLSKNGSSIPRSESASKGLNQMNNGNGSNKKVELSRMSSTKSSG
SESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPDSPTRSQAQTPVLSP
SLPDMSLSTHSSVQSGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGT
WKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQTKENQV
STKGTWRKIKENEISPTNSTSQTTSSGAVNGAESKTLIYQMAPAVSKTEDVWVRIEDCPI
NNPRSGRSPTGNTPPVIDTVSEKGNPNAKDSKDNQGKQNVGNGSAPIRTMGLENRLNSFI
QVDVPDQKGTEAKPGQSNPVPVSETNESSIAERTPFSSSSSSKHSSPSGTVAARVTPFNY
NPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV
NT seq 8634 nt   +upstreamnt  +downstreamnt
atgtacgcctgtctgggctcgggtccggtcgccgttttgcctgcttctgcaccaccctct
actctcgggtcctggagctccggcggcggcggcggcggcggcggcggccgtgtcccgcag
gagaggaagcgcccaggcggcgtccgtacttctggccgcggggcggacgtctggcaggaa
gtacttaaacagctacaaggaagtattgaagatgaagctatggcttcttctggacagatt
gatttattagagcgtctcaaagaacttaatttagatagcagtaatttccctggagtgaaa
ctacgctcaaaaatgtccctccgttcttatggaagccgcgaaggatctgtatctagtcgt
tcaggagagtgcagtcctgttcctatgggttcgtttccaaaaagagggtttgtaaatgga
agcagagaaaatactggttatttagaagaacttgagaaagaaagatcattacttcttgct
gatcttgacaaagaagaaaaggaaaaagactggtattatgctcaacttcagaatctcact
aaaagaatagatagtcttcctttaactgaaaatttttccttacaaacagatatgaccaga
agacaattggaatatgaagcaaggcaaatcagagttgcaatggaagaacaactaggtact
tgccaggatatggagaaaagagcacagcgaagagtaaccagaattcaacaaatagagaag
gacatacttcgtatacgacagcttttacagtcccaagccacagaagcagagaggtcatct
cagagcaagcatgaagccagctcacatgaagctgagcggcagaatgaaggtcaaggagtg
gcagaaatcaacatggcaactcctggtagtggtcagggttcagctgcgcgaatggatcat
gaaacagccagtgttttgagttctagtagcacacactctgctcctcgaaggctgacaagt
catctgggaaccaaggtggaaatggtgtattcattgttatcaatgcttggtactcatgat
aaggatgatatgtcgcgaactttgctagctatgtctagctcccaagacagctgtatatcc
atgcgacagtctggatgtcttcctctcctcatccagcttttacatggcaatgacaaagac
tctgtgttgttgggaaattcccggggcagtaaagaggctcgggccagggccagtgcagca
cttcacaacatcattcactcacagcctgatgacaagagaggcaggcgtgaaatccgagtc
cttcatcttttggaacagatacgagcttactgtgaaacctgttgggagtggcaggaagcc
catgaacaaggcatggaccaggacaaaaatccaatgccagctcctgttgaacatcagatc
tgtcctgctgtgtgtgttctaatgaaactttcatttgatgaagaacatagacatgcaatg
aatgaacttggtaggaaggctacccggggcatttcatcacaggagctagggcaggggctt
gcagggggactacaggccattgcagaattattgcaggtggactgtgaaatgtatgggcta
actaatgaccactacagtattacattaagacgatatgctggaatggctttgacaaacttg
acttttggagatgtagccaacaaggctacactctgctctatgaaaggctgcatgagagca
cttgtggcccaactaaaatctgaaagtgaagacttacagcaggttattgcaagtgttttg
aggaatttgtcttggcgagcagatgtaaatagtaaaaagacattgcgcgaagttggaagt
gtgaaagcattaatggaatgtgctttggaagttaaaaaggaatcaactctcaaaagcgta
ttgagtgccttatggaatttgtcagcacattgcactgagaataaagctgatatatgtgct
gtagatggtgcgcttgcatttctggttggcactctcacttaccgaagccagacaaatact
ttagccattattgaaagtggaggtggaatattacggaacgtgtccagcttgatagctaca
aacgaggaccacaggcaaatcctaagagagaacaactgcctgcaaaccttattacaacac
ttgaaatctcacagtttgacaatagtcagtaatgcatgtggaaccttgtggaatctctca
gcaagaaatcctaaagaccaggaagcattatgggacatgggggcagtcagcatgctcaag
aacctcattcattcaaagcacaaaatgattgctatgggaagcgctgcagctttaaggaat
ctcatggcaaatagacctgcaaagtataaggatgccaatataatgtctcctggttcaagc
ttgccatctcttcatgtcaggaaacaaaaagccctagaagcagaattagatgctcagcat
ttatcagaaacttttgacaatattgacaatttaagtcccaaggcatctcatcgtagtaag
caacgacacaagccaaatctttatggtgactatgtttttgacaccaatcgacatgatgat
aatagatcagacaattttaatactggaaacatgactgtcctttcaccatatttaaatact
acagtgttgcccagctcctcttcatcaagaggaagtttagacagttctcgttctgaaaaa
gatagaagtttggagagagaacgaggaattagcctaggcaactaccacccagcaacagaa
aatccaggcacttcttcaaaacgaggtttgcagatttccaccactgcagcccagattgcc
aaagtcatggaagaagtatcagccattcacacctcccaggaagacagaagttctgggtct
accggcgagttacattgtgggacagatgagaggaatgcactaagaagaagctccactgcc
cacacacatgcaaacacttacaacttcactaagtcagaaaattcaaataggacatgtcct
atgccttatgccaaattggaatataagagatcttcaaatgatagtttaaatagtgtcagt
agtagtgatggttatggtaaaagaggtcagatgaagccttccattgaatcctattctgaa
gatgatgaaagtaaattttgcagctatggtcagtatccagctgacctagcccataaaata
cacagcgcaaatcatatggatgataatgatggagaactagatacaccaataaattatagt
cttaaatattcagatgagcagttgaactccggaaggcaaagcccttcacagaatgaaaga
tgggcaagacccaaacatataatagaagatgaaataaaacagagtgagcaaagacaatca
agaagtcaaagcacaacttaccccgtatatactgagagcactgatgataaacatctcaag
tttcagccacattttggacagcaggaatgtgtttccccatataggtcaagaggagccaat
ggttcagaaacaaatcgagtaagttccaatcatggaattaatcaaaatgtaaaccagtct
ttgtgtcaggaagatgactatgaagatgataagccaaccaactatagtgaacgttactcc
gaggaagagcagcatgaagaagaagagagaccaacaaattatagcataaagtataatgaa
gagaaacatcatgtggatcaacctatcgattatagtttaaaatatgccacagacattcct
gcctcacagaaaccaccattttcattctcaaagagttcatctggacaaagcactaaaact
gaacatatctcttcaagcagtgagaatacatccacaccttcatctaatgccaagaggcag
aatcagcaccatccaagttccacacaaagcagaaatggtcagaccccaaaagccacctcc
tgcaaagttccctctatcaaccaagaaacaatacagacttactgtgtagaggatacccca
atatgtttctcacgttgcagttcactatcatctttgtcatcggccgaagatgaaatagga
tgtgatcagacaacacaggaaacagattctgctaatactctacaaatagcagaaataaaa
gaaaacagtgggactagatcaacagaagagtctgtgagtgaagttccaacagtgtcacag
cacattagaaccaaatccagcagacttcaggcttctggtttatctgcagaatcgaccagg
cataaagctgttgaattttcttcaggggctaaatctccatcaaaaagtggtgctcagaca
cctaaaagtccaccagaacactacgttcaggagactccactcatgtttagcagatgcact
tctgtcagttcacttgatagttttgagagtcgttcgattgccagctccgttcagagtgaa
ccctgcagtggaatggtaagtggcattataagccccagtgaccttccagatagccctgga
caaaccatgccaccaagcagaagtaaaacccctcctcctcctcctcctcagacagttcag
agtaagcgagaggtacctaaaaacaaagcccctactgcggaaaagagagagagtggaccg
aagcaagctgctgtaaatgctgcagtacagagagtccaggtgcttccggatgctgatact
ctcttacattttgccacagaaagtactccagatggattttcttgttcatctagcctgagt
gctctgagcctcgatgagccatttatacagaaagatgtggaattaagaataatgcctcca
gttcaggaaaatgacaatgggaatgaaaccgaatctgagcagcctgaagaagcaaatgaa
agccaggtaaaagaagcagaaaaacctactgattctgaaaaagatctgttagatgactca
gatgatgatgatattgaaatattagaagaatgtattatttctgccatgccaacaaaatct
tcacgtaaagccaaaaaaccagcccagactgctccaaaattacctccacctgtggcaagg
aaaccaagtcaactccctgtgtataaacttcttccatcacaaaacaggttacaggcacaa
aaacatgttagttttacaccaggagatgatatgccacgggtgtattgtgtagaagggaca
cctataaacttttccacagctacatctttaagtgatctaacaatagaatctcctccaaat
gagttagctgctggagaaggggttagagcaggagcacagtccggtgaatttgaaaaacga
gataccattcctacagaaggcagaagtacagatgaggctcaaagagtaaaaacctcatct
gcaactatatctgaactggatgacaataaaacagaagaaggtgatattcttgcagaatgc
attaactctgctatgcccaaaggaaaaagtcacaagcctttccgtgtgaagaagataatg
gaccaggtccaacaagcatctatgtcttcatctggagctaacaaaaatcagttagatggt
aagaaaaagaaacctacttcaccagtaaaacctataccacaaaatactgaatataggaca
cgtgtaagaaaaaacacagactcaaaaaataatttaaatgctgaaagaactttctcagac
aacaaagattcaaagaaacagaacttgaaaaataattccaaggacttcaatgataagcta
ccaaataatgaagatcgagtcagaggaagttttacttttgattcacctcatcattacact
cccattgaaggaactccatactgtttttcacgaaatgattctttgagttctctagatttt
gatgatgatgatgttgacctttctagagaaaaggctgaattaagaaaggggaaagaaaat
aaagaatcagaagctaaagttaccagccacacagaactaacctctagccaacaatcagct
aataagacacaagctgttacaaaacatccaataaatcgaggtcagtctaaacccatgctg
cagaagcaatccacttttccacagtcatccaaagacataccagacaggggagcagcaact
gatgagaaattacaaaattttgctattgaaaatactccggtgtgcttttctcgaaattcc
tctttaagttctcttagtgacattgatcaagaaaacaacaataacaaagaaggtgaacct
gtcaaagagacagagccccctgactcacagggagaacccagtaaacctcaggcatcaggt
tatgctcctaaatcatttcatgttgaagatacccctgtttgtttctcacgaaatagttct
ctcagttctcttagtattgattctgaagatgacctgttgcaggaatgtataagttctgca
atgccaaaaaagaaaaagccttcaagactcaagggtgataatgaaaagcatagtcccaga
aatatgagtggcatattggcagaagatttgacacttgatttgaaagatatacagagacca
gattcagaacatggtttatccccggattcagaaaattttgattggaaagctattcaggaa
ggtgcaaattccatagtaagtagtttacatcaagctgctgctgctgcatgtttatctaga
caggcatcatctgactcagactccatcctttcactgaaatcagggatctccctaggatca
ccatttcatcttacacctgatcaagaggaaaaaccctttacaagtaataagggcccacga
attctaaaacctggggagaagagtacattggaaactaaaaagatagaatctgaaaataaa
ggaatcaaaggaggaaaaaaagtttatagaagtttaattaccggaaaagttcgttctaat
tcagaaatttcaagccaaatgaaacagcctcttcaaacaaacatgccttcaatctctcgg
ggcaggacaatgattcatattccaggagttcgaaatagctcttcaagtacaagtccagtt
tctaaaaaaggcccaccccttaagactccagcctccaaaagccctagtgaaggtcagcca
gccaccacttctcctagaggaaccaagccatctgtgaagtcagaattaagccctgttacc
aggcagacatcccaaccagctggagcaaataaagggtcttctagatcaggatctagagat
tccactccttcaagacctgcccaacaaccattaagtagacctatgcagtctccggggcgg
aactcaatttctcctggtcgaaatggaataagccctcctaataaattatcccagttgcca
aggacttcatcccctagtactgcttcaactaagtcctcaggttctgggaagatgtcatac
acatctccaggcagacagatgagccagcagaaccttaccaagcaaacgggtttatccaag
aatggcagcagtatcccaagaagtgagtctgcctccaaaggactaaatcagatgaataat
gggaatggatccaataaaaaggtagaactttctagaatgtcctcaactaaatcaagtgga
agtgaatctgataggtcagagagacccgtattagtacgccagtcaactttcatcaaagaa
gctccaagcccaaccctaaggagaaaattggaggaatctgcttcatttgaatctctttct
ccatcttctagaccagattctcccactaggtcccaggcacagactccagttttaagtcct
tcccttcctgatatgtctctgtccacacattcatctgttcagtctggtggatggcgaaaa
ctcccacctaatctcagtcccaccatagagtataatgatggaagaccagcaaagcgccat
gatatagcacgctcccattctgaaagtccttctagacttccaattaataggtcaggaacc
tggaaacgtgagcacagcaaacattcatcatcccttccacgagtaagcacttggagaaga
actggaagttcatcctcaattctttctgcttcatcagaatccagtgaaaaagcaaaaagt
gaagatgaaaaacatgtgaactctatttcaggaaccaaacaaactaaagaaaaccaagta
tccacaaaaggaacatggagaaaaataaaagaaaatgagatttctcccacaaatagtacc
tctcagaccacttcctcaggtgctgtaaatggtgctgaatcaaagactctgatttatcaa
atggcacctgctgtttctaaaacagaggatgtttgggtgagaattgaggactgtcccatc
aacaaccctagatccggaagatccccaacaggaaatactccccccgtgattgacactgtt
tcagaaaagggaaatccaaatgctaaagattcaaaagataatcagggaaaacaaaatgtg
ggtaatggcagtgctcccatacgcaccatgggtttggaaaaccgcctgaactcctttatt
caggtagatgtcccagaccagaaaggaactgaggctaaaccgggacaaagtaaccctgtc
cctgtgtcagagactaatgaaagttccatagctgagcgtactcctttcagttctagcagt
tcaagcaagcacagttcacctagcgggactgttgctgccagagtgactccgtttaactac
aatccaagccctaggaaaagcagcgcagatagcacttcagctcggccatctcagatcccg
acaccagtgaacaacaacacgaagaaacgagattcaaaaactgacagcacagaatccagt
ggaactcaaagtcctaagcgccattctgggtcttaccttgtaacatctgtttaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (13)   
   RefSeq(pep) (13)   
DNA sequence (13)   
   RefSeq(nuc) (13)   
Protein domain (17)   
   Pfam (17)   
All databases (45)   

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