KEGG   Pseudorca crassidens (false killer whale): 137232059
Entry
137232059         CDS       T12027                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pcrs  Pseudorca crassidens (false killer whale)
Pathway
pcrs01522  Endocrine resistance
pcrs04010  MAPK signaling pathway
pcrs04015  Rap1 signaling pathway
pcrs04068  FoxO signaling pathway
pcrs04071  Sphingolipid signaling pathway
pcrs04114  Oocyte meiosis
pcrs04148  Efferocytosis
pcrs04218  Cellular senescence
pcrs04261  Adrenergic signaling in cardiomyocytes
pcrs04370  VEGF signaling pathway
pcrs04380  Osteoclast differentiation
pcrs04517  IgSF CAM signaling
pcrs04519  Cadherin signaling
pcrs04550  Signaling pathways regulating pluripotency of stem cells
pcrs04611  Platelet activation
pcrs04613  Neutrophil extracellular trap formation
pcrs04620  Toll-like receptor signaling pathway
pcrs04621  NOD-like receptor signaling pathway
pcrs04622  RIG-I-like receptor signaling pathway
pcrs04625  C-type lectin receptor signaling pathway
pcrs04657  IL-17 signaling pathway
pcrs04658  Th1 and Th2 cell differentiation
pcrs04659  Th17 cell differentiation
pcrs04660  T cell receptor signaling pathway
pcrs04664  Fc epsilon RI signaling pathway
pcrs04668  TNF signaling pathway
pcrs04670  Leukocyte transendothelial migration
pcrs04714  Thermogenesis
pcrs04722  Neurotrophin signaling pathway
pcrs04723  Retrograde endocannabinoid signaling
pcrs04728  Dopaminergic synapse
pcrs04750  Inflammatory mediator regulation of TRP channels
pcrs04912  GnRH signaling pathway
pcrs04914  Progesterone-mediated oocyte maturation
pcrs04917  Prolactin signaling pathway
pcrs04926  Relaxin signaling pathway
pcrs04932  Non-alcoholic fatty liver disease
pcrs04933  AGE-RAGE signaling pathway in diabetic complications
pcrs04935  Growth hormone synthesis, secretion and action
pcrs04936  Alcoholic liver disease
pcrs05014  Amyotrophic lateral sclerosis
pcrs05020  Prion disease
pcrs05022  Pathways of neurodegeneration - multiple diseases
pcrs05132  Salmonella infection
pcrs05133  Pertussis
pcrs05135  Yersinia infection
pcrs05140  Leishmaniasis
pcrs05142  Chagas disease
pcrs05145  Toxoplasmosis
pcrs05152  Tuberculosis
pcrs05161  Hepatitis B
pcrs05163  Human cytomegalovirus infection
pcrs05167  Kaposi sarcoma-associated herpesvirus infection
pcrs05169  Epstein-Barr virus infection
pcrs05170  Human immunodeficiency virus 1 infection
pcrs05171  Coronavirus disease
pcrs05205  Proteoglycans in cancer
pcrs05208  Chemical carcinogenesis - reactive oxygen species
pcrs05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcrs05415  Diabetic cardiomyopathy
pcrs05417  Lipid and atherosclerosis
pcrs05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcrs00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    137232059 (MAPK13)
   04015 Rap1 signaling pathway
    137232059 (MAPK13)
   04370 VEGF signaling pathway
    137232059 (MAPK13)
   04668 TNF signaling pathway
    137232059 (MAPK13)
   04068 FoxO signaling pathway
    137232059 (MAPK13)
   04071 Sphingolipid signaling pathway
    137232059 (MAPK13)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    137232059 (MAPK13)
   04519 Cadherin signaling
    137232059 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    137232059 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    137232059 (MAPK13)
   04218 Cellular senescence
    137232059 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    137232059 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    137232059 (MAPK13)
   04613 Neutrophil extracellular trap formation
    137232059 (MAPK13)
   04620 Toll-like receptor signaling pathway
    137232059 (MAPK13)
   04621 NOD-like receptor signaling pathway
    137232059 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    137232059 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    137232059 (MAPK13)
   04660 T cell receptor signaling pathway
    137232059 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    137232059 (MAPK13)
   04659 Th17 cell differentiation
    137232059 (MAPK13)
   04657 IL-17 signaling pathway
    137232059 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    137232059 (MAPK13)
   04670 Leukocyte transendothelial migration
    137232059 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    137232059 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    137232059 (MAPK13)
   04917 Prolactin signaling pathway
    137232059 (MAPK13)
   04926 Relaxin signaling pathway
    137232059 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    137232059 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    137232059 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    137232059 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    137232059 (MAPK13)
   04722 Neurotrophin signaling pathway
    137232059 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    137232059 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    137232059 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    137232059 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    137232059 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    137232059 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    137232059 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    137232059 (MAPK13)
   05161 Hepatitis B
    137232059 (MAPK13)
   05171 Coronavirus disease
    137232059 (MAPK13)
   05163 Human cytomegalovirus infection
    137232059 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    137232059 (MAPK13)
   05169 Epstein-Barr virus infection
    137232059 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    137232059 (MAPK13)
   05135 Yersinia infection
    137232059 (MAPK13)
   05133 Pertussis
    137232059 (MAPK13)
   05152 Tuberculosis
    137232059 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    137232059 (MAPK13)
   05140 Leishmaniasis
    137232059 (MAPK13)
   05142 Chagas disease
    137232059 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    137232059 (MAPK13)
   05020 Prion disease
    137232059 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    137232059 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    137232059 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    137232059 (MAPK13)
   05415 Diabetic cardiomyopathy
    137232059 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    137232059 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    137232059 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    137232059 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    137232059 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcrs01001]
    137232059 (MAPK13)
Enzymes [BR:pcrs01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     137232059 (MAPK13)
Protein kinases [BR:pcrs01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   137232059 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 APH Kinase-like GVIN1_N
Other DBs
NCBI-GeneID: 137232059
NCBI-ProteinID: XP_067609275
Position
10:complement(38669263..38681685)
AA seq 448 aa
MNFTWKKGFYKQDVNKTAWELPKTYVSLTHVGSGAYGAVCSAIEKQSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFFTTKETSLPVPTGFAST
YLTISWGRSYLVMPFMQMDLQKIMGMEFGEDKIQYLVYQMLKGLKYIHSAGVIHRDLKPG
NLAVNEDCELKILDFGLARQADAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMA
EMLTGKTLFKGKDYLDQLTQILKVTGVPDAEFVQKLNDKAAKSYIQSLPQTPKKDFSQLF
QHASPQAADLLEKMLELDMDKRLTASQALTHPFFESCRDPEEETEAQQPFDDFLEQEKLT
VDEWKRKGSGPRAASSLCLQHPSPLPASFSCLPSAGPNPLLETITSFSLSEYRLLCALLS
PCAELTFCSTLCLLGEGGSLLPSAPRTP
NT seq 1347 nt   +upstreamnt  +downstreamnt
atgaacttcacctggaaaaagggcttctacaagcaggacgtcaacaagaccgcctgggag
ctgcccaagacctacgtgtccctgacgcacgtaggcagcggggcctacggcgccgtgtgc
tcagccatcgagaagcagtcaggggagaaggtggccatcaagaaactgagccggcccttc
cagtctgagatctttgccaagcgggcctatcgcgagctgctgctgctgaagcacatgcag
catgagaacgtcatcggactcctggatgtcttcaccccagcctcttccctgcgcaacttt
catgatttctttaccaccaaagagacatcgttgccagtccccacagggtttgcatcaacc
tacctcaccatttcctggggacgcagctacctggtgatgcccttcatgcaaatggacctg
cagaagatcatgggaatggagttcggtgaggacaagatccagtacctggtgtatcagatg
ctcaaaggtcttaagtacatccactcagctggggtcatccacagggacctgaagccaggc
aaccttgctgtcaatgaggattgtgagctgaagattttggattttgggttggcacggcaa
gcagatgcagagatgaccggctatgtggtgacccgctggtaccgggcccctgaggtgatc
ctcagctggatgcactacaaccagactgtggacatctggtctgtgggctgtatcatggcg
gagatgctgacggggaaaactctgttcaaggggaaagattacctggaccagctgacgcag
atcctgaaagtgacgggggtgccggacgctgagtttgtgcagaagttgaatgacaaagcg
gccaaatcctacatccagtccctgccacaaacccccaagaaggatttctctcagctcttc
cagcatgccagcccccaggctgcagacctgctggagaagatgctggagctggacatggac
aagcgcctgaccgcctctcaggccctcacgcaccccttctttgaatcctgccgggaccct
gaggaggaaacagaggcccagcagccatttgatgatttcttagaacaggagaaactcaca
gtggatgaatggaagcgtaagggctcggggcctcgggctgcttcctctctctgcctgcag
cacccctctcctctgcctgcttcgttttcctgcctgccctcagccggtcccaaccccctc
ctggagactatcacctctttctctctgagcgaatatcgtctcctgtgtgcacttctttct
ccctgcgctgagctgactttctgctccacactatgtctgttgggagaggggggctctctc
ttgccctcagcaccccgtaccccttga

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