GenomeNet

Database: PDB
Entry: 5VFR
LinkDB: 5VFR
Original site: 5VFR 
HEADER    HYDROLASE                               09-APR-17   5VFR              
TITLE     NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL IN
TITLE    2 THE ACTIVATED HUMAN 26S PROTEASOME                                   
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1;            
COMPND   3 CHAIN: U;                                                            
COMPND   4 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN2,26S PROTEASOME       
COMPND   5 REGULATORY SUBUNIT S1,26S PROTEASOME SUBUNIT P112;                   
COMPND   6 ENGINEERED: YES;                                                     
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3;            
COMPND   9 CHAIN: V;                                                            
COMPND  10 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN3,26S PROTEASOME       
COMPND  11 REGULATORY SUBUNIT S3,PROTEASOME SUBUNIT P58;                        
COMPND  12 ENGINEERED: YES;                                                     
COMPND  13 MOL_ID: 3;                                                           
COMPND  14 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12;           
COMPND  15 CHAIN: W;                                                            
COMPND  16 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN5,26S PROTEASOME       
COMPND  17 REGULATORY SUBUNIT P55;                                              
COMPND  18 ENGINEERED: YES;                                                     
COMPND  19 MOL_ID: 4;                                                           
COMPND  20 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11;           
COMPND  21 CHAIN: X;                                                            
COMPND  22 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN6,26S PROTEASOME       
COMPND  23 REGULATORY SUBUNIT S9,26S PROTEASOME REGULATORY SUBUNIT P44.5;       
COMPND  24 ENGINEERED: YES;                                                     
COMPND  25 MOL_ID: 5;                                                           
COMPND  26 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6;            
COMPND  27 CHAIN: Y;                                                            
COMPND  28 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN7,26S PROTEASOME       
COMPND  29 REGULATORY SUBUNIT S10,BREAST CANCER-ASSOCIATED PROTEIN SGA-113M,    
COMPND  30 PHOSPHONOFORMATE IMMUNO-ASSOCIATED PROTEIN 4,PROTEASOME REGULATORY   
COMPND  31 PARTICLE SUBUNIT P44S10,P42A;                                        
COMPND  32 ENGINEERED: YES;                                                     
COMPND  33 MOL_ID: 6;                                                           
COMPND  34 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7;            
COMPND  35 CHAIN: Z;                                                            
COMPND  36 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN8,26S PROTEASOME       
COMPND  37 REGULATORY SUBUNIT S12,MOV34 PROTEIN HOMOLOG,PROTEASOME SUBUNIT P40; 
COMPND  38 ENGINEERED: YES;                                                     
COMPND  39 MOL_ID: 7;                                                           
COMPND  40 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13;           
COMPND  41 CHAIN: a;                                                            
COMPND  42 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN9,26S PROTEASOME       
COMPND  43 REGULATORY SUBUNIT S11,26S PROTEASOME REGULATORY SUBUNIT P40.5;      
COMPND  44 ENGINEERED: YES;                                                     
COMPND  45 MOL_ID: 8;                                                           
COMPND  46 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4;            
COMPND  47 CHAIN: b;                                                            
COMPND  48 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN10,26S PROTEASOME      
COMPND  49 REGULATORY SUBUNIT S5A,ANTISECRETORY FACTOR 1,ASF,MULTIUBIQUITIN     
COMPND  50 CHAIN-BINDING PROTEIN;                                               
COMPND  51 ENGINEERED: YES;                                                     
COMPND  52 MOL_ID: 9;                                                           
COMPND  53 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14;           
COMPND  54 CHAIN: c;                                                            
COMPND  55 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN11,26S PROTEASOME-     
COMPND  56 ASSOCIATED PAD1 HOMOLOG 1;                                           
COMPND  57 EC: 3.4.19.-;                                                        
COMPND  58 ENGINEERED: YES;                                                     
COMPND  59 MOL_ID: 10;                                                          
COMPND  60 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8;            
COMPND  61 CHAIN: d;                                                            
COMPND  62 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN12,26S PROTEASOME      
COMPND  63 REGULATORY SUBUNIT S14,P31;                                          
COMPND  64 ENGINEERED: YES;                                                     
COMPND  65 MOL_ID: 11;                                                          
COMPND  66 MOLECULE: SEM1;                                                      
COMPND  67 CHAIN: e;                                                            
COMPND  68 ENGINEERED: YES;                                                     
COMPND  69 MOL_ID: 12;                                                          
COMPND  70 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-6;                           
COMPND  71 CHAIN: G, g;                                                         
COMPND  72 SYNONYM: 27 KDA PROSOMAL PROTEIN,P27K,MACROPAIN IOTA CHAIN,          
COMPND  73 MULTICATALYTIC ENDOPEPTIDASE COMPLEX IOTA CHAIN,PROTEASOME IOTA      
COMPND  74 CHAIN;                                                               
COMPND  75 EC: 3.4.25.1;                                                        
COMPND  76 ENGINEERED: YES;                                                     
COMPND  77 MOL_ID: 13;                                                          
COMPND  78 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-2;                           
COMPND  79 CHAIN: H, h;                                                         
COMPND  80 SYNONYM: MACROPAIN SUBUNIT C3,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND  81 SUBUNIT C3,PROTEASOME COMPONENT C3;                                  
COMPND  82 EC: 3.4.25.1;                                                        
COMPND  83 ENGINEERED: YES;                                                     
COMPND  84 MOL_ID: 14;                                                          
COMPND  85 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-4;                           
COMPND  86 CHAIN: I, i;                                                         
COMPND  87 SYNONYM: MACROPAIN SUBUNIT C9,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND  88 SUBUNIT C9,PROTEASOME COMPONENT C9,PROTEASOME SUBUNIT L;             
COMPND  89 EC: 3.4.25.1;                                                        
COMPND  90 ENGINEERED: YES;                                                     
COMPND  91 MOL_ID: 15;                                                          
COMPND  92 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-7;                           
COMPND  93 CHAIN: J, j;                                                         
COMPND  94 SYNONYM: PROTEASOME SUBUNIT RC6-1,PROTEASOME SUBUNIT XAPC7;          
COMPND  95 EC: 3.4.25.1;                                                        
COMPND  96 ENGINEERED: YES;                                                     
COMPND  97 MOL_ID: 16;                                                          
COMPND  98 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-5;                           
COMPND  99 CHAIN: K, k;                                                         
COMPND 100 SYNONYM: MACROPAIN ZETA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 101 ZETA CHAIN,PROTEASOME ZETA CHAIN;                                    
COMPND 102 EC: 3.4.25.1;                                                        
COMPND 103 ENGINEERED: YES;                                                     
COMPND 104 MOL_ID: 17;                                                          
COMPND 105 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-1;                           
COMPND 106 CHAIN: L, l;                                                         
COMPND 107 SYNONYM: 30 KDA PROSOMAL PROTEIN,PROS-30,MACROPAIN SUBUNIT C2,       
COMPND 108 MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C2,PROTEASOME COMPONENT 
COMPND 109 C2,PROTEASOME NU CHAIN;                                              
COMPND 110 EC: 3.4.25.1;                                                        
COMPND 111 ENGINEERED: YES;                                                     
COMPND 112 MOL_ID: 18;                                                          
COMPND 113 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-3;                           
COMPND 114 CHAIN: M, m;                                                         
COMPND 115 SYNONYM: MACROPAIN SUBUNIT C8,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 116 SUBUNIT C8,PROTEASOME COMPONENT C8;                                  
COMPND 117 EC: 3.4.25.1;                                                        
COMPND 118 ENGINEERED: YES;                                                     
COMPND 119 MOL_ID: 19;                                                          
COMPND 120 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-6;                            
COMPND 121 CHAIN: N, n;                                                         
COMPND 122 SYNONYM: MACROPAIN DELTA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX  
COMPND 123 DELTA CHAIN,PROTEASOME DELTA CHAIN,PROTEASOME SUBUNIT Y;             
COMPND 124 EC: 3.4.25.1;                                                        
COMPND 125 ENGINEERED: YES;                                                     
COMPND 126 MOL_ID: 20;                                                          
COMPND 127 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-7;                            
COMPND 128 CHAIN: O, o;                                                         
COMPND 129 SYNONYM: MACROPAIN CHAIN Z,MULTICATALYTIC ENDOPEPTIDASE COMPLEX CHAIN
COMPND 130 Z,PROTEASOME SUBUNIT Z;                                              
COMPND 131 EC: 3.4.25.1;                                                        
COMPND 132 ENGINEERED: YES;                                                     
COMPND 133 MOL_ID: 21;                                                          
COMPND 134 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-3;                            
COMPND 135 CHAIN: P, p;                                                         
COMPND 136 SYNONYM: PROTEASOME CHAIN 13,PROTEASOME COMPONENT C10-II,PROTEASOME  
COMPND 137 THETA CHAIN;                                                         
COMPND 138 EC: 3.4.25.1;                                                        
COMPND 139 ENGINEERED: YES;                                                     
COMPND 140 MOL_ID: 22;                                                          
COMPND 141 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-2;                            
COMPND 142 CHAIN: Q, q;                                                         
COMPND 143 SYNONYM: MACROPAIN SUBUNIT C7-I,MULTICATALYTIC ENDOPEPTIDASE COMPLEX 
COMPND 144 SUBUNIT C7-I,PROTEASOME COMPONENT C7-I;                              
COMPND 145 EC: 3.4.25.1;                                                        
COMPND 146 ENGINEERED: YES;                                                     
COMPND 147 MOL_ID: 23;                                                          
COMPND 148 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-5;                            
COMPND 149 CHAIN: R, r;                                                         
COMPND 150 SYNONYM: MACROPAIN EPSILON CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 151 EPSILON CHAIN,PROTEASOME CHAIN 6,PROTEASOME EPSILON CHAIN,PROTEASOME 
COMPND 152 SUBUNIT MB1,PROTEASOME SUBUNIT X;                                    
COMPND 153 EC: 3.4.25.1;                                                        
COMPND 154 ENGINEERED: YES;                                                     
COMPND 155 MOL_ID: 24;                                                          
COMPND 156 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-1;                            
COMPND 157 CHAIN: S, s;                                                         
COMPND 158 SYNONYM: MACROPAIN SUBUNIT C5,MULTICATALYTIC ENDOPEPTIDASE COMPLEX   
COMPND 159 SUBUNIT C5,PROTEASOME COMPONENT C5,PROTEASOME GAMMA CHAIN;           
COMPND 160 EC: 3.4.25.1;                                                        
COMPND 161 ENGINEERED: YES;                                                     
COMPND 162 MOL_ID: 25;                                                          
COMPND 163 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-4;                            
COMPND 164 CHAIN: T, t;                                                         
COMPND 165 SYNONYM: 26 KDA PROSOMAL PROTEIN,PROS-26,MACROPAIN BETA CHAIN,       
COMPND 166 MULTICATALYTIC ENDOPEPTIDASE COMPLEX BETA CHAIN,PROTEASOME BETA      
COMPND 167 CHAIN,PROTEASOME CHAIN 3,HSN3;                                       
COMPND 168 EC: 3.4.25.1;                                                        
COMPND 169 ENGINEERED: YES;                                                     
COMPND 170 MOL_ID: 26;                                                          
COMPND 171 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 7;                       
COMPND 172 CHAIN: A;                                                            
COMPND 173 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT1,PROTEASOME 26S       
COMPND 174 SUBUNIT ATPASE 2,PROTEIN MSS1;                                       
COMPND 175 ENGINEERED: YES;                                                     
COMPND 176 MOL_ID: 27;                                                          
COMPND 177 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 4;                       
COMPND 178 CHAIN: B;                                                            
COMPND 179 SYNONYM: P26S4,26S PROTEASOME AAA-ATPASE SUBUNIT RPT2,PROTEASOME 26S 
COMPND 180 SUBUNIT ATPASE 1;                                                    
COMPND 181 ENGINEERED: YES;                                                     
COMPND 182 MOL_ID: 28;                                                          
COMPND 183 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 8;                       
COMPND 184 CHAIN: C;                                                            
COMPND 185 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT6,PROTEASOME 26S       
COMPND 186 SUBUNIT ATPASE 5,PROTEASOME SUBUNIT P45,THYROID HORMONE RECEPTOR-    
COMPND 187 INTERACTING PROTEIN 1,TRIP1,P45/SUG;                                 
COMPND 188 ENGINEERED: YES;                                                     
COMPND 189 MOL_ID: 29;                                                          
COMPND 190 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 6B;                      
COMPND 191 CHAIN: D;                                                            
COMPND 192 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT3,MB67-INTERACTING     
COMPND 193 PROTEIN,MIP224,PROTEASOME 26S SUBUNIT ATPASE 4,TAT-BINDING PROTEIN 7,
COMPND 194 TBP-7;                                                               
COMPND 195 ENGINEERED: YES;                                                     
COMPND 196 MOL_ID: 30;                                                          
COMPND 197 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 10B;                     
COMPND 198 CHAIN: E;                                                            
COMPND 199 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT4,PROTEASOME 26S       
COMPND 200 SUBUNIT ATPASE 6,PROTEASOME SUBUNIT P42;                             
COMPND 201 ENGINEERED: YES;                                                     
COMPND 202 MOL_ID: 31;                                                          
COMPND 203 MOLECULE: 26S PROTEASOME REGULATORY SUBUNIT 6A;                      
COMPND 204 CHAIN: F;                                                            
COMPND 205 SYNONYM: 26S PROTEASOME AAA-ATPASE SUBUNIT RPT5,PROTEASOME 26S       
COMPND 206 SUBUNIT ATPASE 3,PROTEASOME SUBUNIT P50,TAT-BINDING PROTEIN 1,TBP-1; 
COMPND 207 ENGINEERED: YES;                                                     
COMPND 208 MOL_ID: 32;                                                          
COMPND 209 MOLECULE: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2;            
COMPND 210 CHAIN: f;                                                            
COMPND 211 SYNONYM: 26S PROTEASOME REGULATORY SUBUNIT RPN1,26S PROTEASOME       
COMPND 212 REGULATORY SUBUNIT S2,26S PROTEASOME SUBUNIT P97,PROTEIN 55.11,TUMOR 
COMPND 213 NECROSIS FACTOR TYPE 1 RECEPTOR-ASSOCIATED PROTEIN 2;                
COMPND 214 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 GENE: PSMD1;                                                         
SOURCE   6 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE   7 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE   8 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE   9 MOL_ID: 2;                                                           
SOURCE  10 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  11 ORGANISM_COMMON: HUMAN;                                              
SOURCE  12 ORGANISM_TAXID: 9606;                                                
SOURCE  13 GENE: PSMD3;                                                         
SOURCE  14 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  15 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  16 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  17 MOL_ID: 3;                                                           
SOURCE  18 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  19 ORGANISM_COMMON: HUMAN;                                              
SOURCE  20 ORGANISM_TAXID: 9606;                                                
SOURCE  21 GENE: PSMD12;                                                        
SOURCE  22 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  23 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  24 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  25 MOL_ID: 4;                                                           
SOURCE  26 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  27 ORGANISM_COMMON: HUMAN;                                              
SOURCE  28 ORGANISM_TAXID: 9606;                                                
SOURCE  29 GENE: PSMD11;                                                        
SOURCE  30 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  31 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  32 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  33 MOL_ID: 5;                                                           
SOURCE  34 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  35 ORGANISM_COMMON: HUMAN;                                              
SOURCE  36 ORGANISM_TAXID: 9606;                                                
SOURCE  37 GENE: PSMD6, KIAA0107, PFAAP4;                                       
SOURCE  38 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  39 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  40 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  41 MOL_ID: 6;                                                           
SOURCE  42 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  43 ORGANISM_COMMON: HUMAN;                                              
SOURCE  44 ORGANISM_TAXID: 9606;                                                
SOURCE  45 GENE: PSMD7, MOV34L;                                                 
SOURCE  46 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  47 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  48 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  49 MOL_ID: 7;                                                           
SOURCE  50 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  51 ORGANISM_COMMON: HUMAN;                                              
SOURCE  52 ORGANISM_TAXID: 9606;                                                
SOURCE  53 GENE: PSMD13;                                                        
SOURCE  54 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  55 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  56 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  57 MOL_ID: 8;                                                           
SOURCE  58 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  59 ORGANISM_COMMON: HUMAN;                                              
SOURCE  60 ORGANISM_TAXID: 9606;                                                
SOURCE  61 GENE: PSMD4, MCB1;                                                   
SOURCE  62 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  63 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  64 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  65 MOL_ID: 9;                                                           
SOURCE  66 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  67 ORGANISM_COMMON: HUMAN;                                              
SOURCE  68 ORGANISM_TAXID: 9606;                                                
SOURCE  69 GENE: PSMD14, POH1;                                                  
SOURCE  70 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  71 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  72 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  73 MOL_ID: 10;                                                          
SOURCE  74 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  75 ORGANISM_COMMON: HUMAN;                                              
SOURCE  76 ORGANISM_TAXID: 9606;                                                
SOURCE  77 GENE: PSMD8;                                                         
SOURCE  78 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  79 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  80 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  81 MOL_ID: 11;                                                          
SOURCE  82 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  83 ORGANISM_COMMON: HUMAN;                                              
SOURCE  84 ORGANISM_TAXID: 9606;                                                
SOURCE  85 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  86 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  87 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  88 MOL_ID: 12;                                                          
SOURCE  89 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  90 ORGANISM_COMMON: HUMAN;                                              
SOURCE  91 ORGANISM_TAXID: 9606;                                                
SOURCE  92 GENE: PSMA6, PROS27;                                                 
SOURCE  93 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE  94 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE  95 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE  96 MOL_ID: 13;                                                          
SOURCE  97 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE  98 ORGANISM_COMMON: HUMAN;                                              
SOURCE  99 ORGANISM_TAXID: 9606;                                                
SOURCE 100 GENE: PSMA2, HC3, PSC3;                                              
SOURCE 101 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 102 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 103 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 104 MOL_ID: 14;                                                          
SOURCE 105 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 106 ORGANISM_COMMON: HUMAN;                                              
SOURCE 107 ORGANISM_TAXID: 9606;                                                
SOURCE 108 GENE: PSMA4, HC9, PSC9;                                              
SOURCE 109 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 110 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 111 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 112 MOL_ID: 15;                                                          
SOURCE 113 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 114 ORGANISM_COMMON: HUMAN;                                              
SOURCE 115 ORGANISM_TAXID: 9606;                                                
SOURCE 116 GENE: PSMA7, HSPC;                                                   
SOURCE 117 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 118 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 119 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 120 MOL_ID: 16;                                                          
SOURCE 121 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 122 ORGANISM_COMMON: HUMAN;                                              
SOURCE 123 ORGANISM_TAXID: 9606;                                                
SOURCE 124 GENE: PSMA5;                                                         
SOURCE 125 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 126 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 127 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 128 MOL_ID: 17;                                                          
SOURCE 129 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 130 ORGANISM_COMMON: HUMAN;                                              
SOURCE 131 ORGANISM_TAXID: 9606;                                                
SOURCE 132 GENE: PSMA1, HC2, NU, PROS30, PSC2;                                  
SOURCE 133 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 134 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 135 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 136 MOL_ID: 18;                                                          
SOURCE 137 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 138 ORGANISM_COMMON: HUMAN;                                              
SOURCE 139 ORGANISM_TAXID: 9606;                                                
SOURCE 140 GENE: PSMA3, HC8, PSC8;                                              
SOURCE 141 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 142 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 143 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 144 MOL_ID: 19;                                                          
SOURCE 145 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 146 ORGANISM_COMMON: HUMAN;                                              
SOURCE 147 ORGANISM_TAXID: 9606;                                                
SOURCE 148 GENE: PSMB6, LMPY, Y;                                                
SOURCE 149 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 150 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 151 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 152 MOL_ID: 20;                                                          
SOURCE 153 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 154 ORGANISM_COMMON: HUMAN;                                              
SOURCE 155 ORGANISM_TAXID: 9606;                                                
SOURCE 156 GENE: PSMB7, Z;                                                      
SOURCE 157 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 158 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 159 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 160 MOL_ID: 21;                                                          
SOURCE 161 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 162 ORGANISM_COMMON: HUMAN;                                              
SOURCE 163 ORGANISM_TAXID: 9606;                                                
SOURCE 164 GENE: PSMB3;                                                         
SOURCE 165 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 166 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 167 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 168 MOL_ID: 22;                                                          
SOURCE 169 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 170 ORGANISM_COMMON: HUMAN;                                              
SOURCE 171 ORGANISM_TAXID: 9606;                                                
SOURCE 172 GENE: PSMB2;                                                         
SOURCE 173 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 174 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 175 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 176 MOL_ID: 23;                                                          
SOURCE 177 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 178 ORGANISM_COMMON: HUMAN;                                              
SOURCE 179 ORGANISM_TAXID: 9606;                                                
SOURCE 180 GENE: PSMB5, LMPX, MB1, X;                                           
SOURCE 181 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 182 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 183 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 184 MOL_ID: 24;                                                          
SOURCE 185 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 186 ORGANISM_COMMON: HUMAN;                                              
SOURCE 187 ORGANISM_TAXID: 9606;                                                
SOURCE 188 GENE: PSMB1, PSC5;                                                   
SOURCE 189 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 190 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 191 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 192 MOL_ID: 25;                                                          
SOURCE 193 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 194 ORGANISM_COMMON: HUMAN;                                              
SOURCE 195 ORGANISM_TAXID: 9606;                                                
SOURCE 196 GENE: PSMB4, PROS26;                                                 
SOURCE 197 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 198 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 199 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 200 MOL_ID: 26;                                                          
SOURCE 201 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 202 ORGANISM_COMMON: HUMAN;                                              
SOURCE 203 ORGANISM_TAXID: 9606;                                                
SOURCE 204 GENE: PSMC2, MSS1;                                                   
SOURCE 205 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 206 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 207 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 208 MOL_ID: 27;                                                          
SOURCE 209 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 210 ORGANISM_COMMON: HUMAN;                                              
SOURCE 211 ORGANISM_TAXID: 9606;                                                
SOURCE 212 GENE: PSMC1;                                                         
SOURCE 213 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 214 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 215 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 216 MOL_ID: 28;                                                          
SOURCE 217 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 218 ORGANISM_COMMON: HUMAN;                                              
SOURCE 219 ORGANISM_TAXID: 9606;                                                
SOURCE 220 GENE: PSMC5, SUG1;                                                   
SOURCE 221 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 222 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 223 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 224 MOL_ID: 29;                                                          
SOURCE 225 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 226 ORGANISM_COMMON: HUMAN;                                              
SOURCE 227 ORGANISM_TAXID: 9606;                                                
SOURCE 228 GENE: PSMC4, MIP224, TBP7;                                           
SOURCE 229 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 230 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 231 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 232 MOL_ID: 30;                                                          
SOURCE 233 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 234 ORGANISM_COMMON: HUMAN;                                              
SOURCE 235 ORGANISM_TAXID: 9606;                                                
SOURCE 236 GENE: PSMC6, SUG2;                                                   
SOURCE 237 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 238 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 239 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 240 MOL_ID: 31;                                                          
SOURCE 241 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 242 ORGANISM_COMMON: HUMAN;                                              
SOURCE 243 ORGANISM_TAXID: 9606;                                                
SOURCE 244 GENE: PSMC3, TBP1;                                                   
SOURCE 245 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 246 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 247 EXPRESSION_SYSTEM_TAXID: 9606;                                       
SOURCE 248 MOL_ID: 32;                                                          
SOURCE 249 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE 250 ORGANISM_COMMON: HUMAN;                                              
SOURCE 251 ORGANISM_TAXID: 9606;                                                
SOURCE 252 GENE: PSMD2, TRAP2;                                                  
SOURCE 253 EXPRESSION_SYSTEM: HOMO SAPIENS;                                     
SOURCE 254 EXPRESSION_SYSTEM_COMMON: HUMAN;                                     
SOURCE 255 EXPRESSION_SYSTEM_TAXID: 9606                                        
KEYWDS    26S PROTEASOME, ATP-DEPENDENT PROTEASE, AAA-ATPASE, PEPTIDE-UNFOLDING 
KEYWDS   2 CHANNEL, 20S CORE PARTICLE, HYDROLASE                                
EXPDTA    ELECTRON MICROSCOPY                                                   
AUTHOR    Y.ZHU,W.L.WANG,D.YU,Q.OUYANG,Y.LU,Y.MAO                               
REVDAT   1   18-JUL-18 5VFR    0                                                
JRNL        AUTH   Y.ZHU,W.L.WANG,D.YU,Q.OUYANG,Y.LU,Y.MAO                      
JRNL        TITL   STRUCTURAL MECHANISM FOR NUCLEOTIDE-DRIVEN REMODELING OF THE 
JRNL        TITL 2 AAA-ATPASE UNFOLDASE IN THE ACTIVATED HUMAN 26S PROTEASOME.  
JRNL        REF    NAT COMMUN                    V.   9  1360 2018              
JRNL        REFN                   ESSN 2041-1723                               
JRNL        PMID   29636472                                                     
JRNL        DOI    10.1038/S41467-018-03785-W                                   
REMARK   2                                                                      
REMARK   2 RESOLUTION.    4.90 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   SOFTWARE PACKAGES      : GCTF, COOT, PHENIX, RELION, RELION,       
REMARK   3                            RELION, RELION                            
REMARK   3   RECONSTRUCTION SCHEMA  : NULL                                      
REMARK   3                                                                      
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT                                  
REMARK   3   PDB ENTRY                    : NULL                                
REMARK   3   REFINEMENT SPACE             : NULL                                
REMARK   3   REFINEMENT PROTOCOL          : NULL                                
REMARK   3   REFINEMENT TARGET            : NULL                                
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL                                
REMARK   3                                                                      
REMARK   3 FITTING PROCEDURE : NULL                                             
REMARK   3                                                                      
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS                                   
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : NULL                           
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : NULL                           
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 4.900                          
REMARK   3   NUMBER OF PARTICLES               : 33278                          
REMARK   3   CTF CORRECTION METHOD             : PHASE FLIPPING AND AMPLITUDE   
REMARK   3                                       CORRECTION                     
REMARK   3                                                                      
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL                    
REMARK   3                                                                      
REMARK   3 OTHER DETAILS: NULL                                                  
REMARK   4                                                                      
REMARK   4 5VFR COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 11-APR-17.                  
REMARK 100 THE DEPOSITION ID IS D_1000227362.                                   
REMARK 245                                                                      
REMARK 245 EXPERIMENTAL DETAILS                                                 
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE                   
REMARK 245   SPECIMEN TYPE                  : NULL                              
REMARK 245                                                                      
REMARK 245 ELECTRON MICROSCOPE SAMPLE                                           
REMARK 245   SAMPLE TYPE                    : PARTICLE                          
REMARK 245   PARTICLE TYPE                  : POINT                             
REMARK 245   NAME OF SAMPLE                 : 26S PROTEASOME BOUND TO ATP       
REMARK 245                                    -GAMMAS                           
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : NULL                              
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL                              
REMARK 245   SAMPLE VITRIFICATION DETAILS   : NULL                              
REMARK 245   SAMPLE BUFFER                  : NULL                              
REMARK 245   PH                             : 7.50                              
REMARK 245   SAMPLE DETAILS                 : NULL                              
REMARK 245                                                                      
REMARK 245 DATA ACQUISITION                                                     
REMARK 245   DATE OF EXPERIMENT                : NULL                           
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : NULL                           
REMARK 245   TEMPERATURE (KELVIN)              : NULL                           
REMARK 245   MICROSCOPE MODEL                  : FEI TECNAI ARCTICA             
REMARK 245   DETECTOR TYPE                     : GATAN K2 SUMMIT (4K X 4K)      
REMARK 245   MINIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MAXIMUM DEFOCUS (NM)              : NULL                           
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL                           
REMARK 245   NOMINAL CS                        : NULL                           
REMARK 245   IMAGING MODE                      : BRIGHT FIELD                   
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 30.00                          
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM                     
REMARK 245   NOMINAL MAGNIFICATION             : NULL                           
REMARK 245   CALIBRATED MAGNIFICATION          : NULL                           
REMARK 245   SOURCE                            : FIELD EMISSION GUN             
REMARK 245   ACCELERATION VOLTAGE (KV)         : 200                            
REMARK 245   IMAGING DETAILS                   : NULL                           
REMARK 247                                                                      
REMARK 247 ELECTRON MICROSCOPY                                                  
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON          
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE              
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES           
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION         
REMARK 247  OF THE STRUCTURE FACTORS.                                           
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 46-MERIC                          
REMARK 350 APPLY THE FOLLOWING TO CHAINS: U, V, W, X, Y, Z, a, b, c, d,         
REMARK 350                    AND CHAINS: e, G, H, I, J, K, L, M, N,            
REMARK 350                    AND CHAINS: O, P, Q, R, S, T, g, h, i, j,         
REMARK 350                    AND CHAINS: k, l, m, n, o, p, q, r, s,            
REMARK 350                    AND CHAINS: t, A, B, C, D, E, F, f                
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     VAL U   271                                                      
REMARK 465     GLY U   272                                                      
REMARK 465     THR U   273                                                      
REMARK 465     PRO U   274                                                      
REMARK 465     ILE U   275                                                      
REMARK 465     ALA U   276                                                      
REMARK 465     SER U   277                                                      
REMARK 465     VAL U   278                                                      
REMARK 465     PRO U   279                                                      
REMARK 465     GLY U   280                                                      
REMARK 465     SER U   281                                                      
REMARK 465     THR U   282                                                      
REMARK 465     ASN U   283                                                      
REMARK 465     THR U   284                                                      
REMARK 465     GLY U   285                                                      
REMARK 465     THR U   286                                                      
REMARK 465     VAL U   287                                                      
REMARK 465     PRO U   288                                                      
REMARK 465     GLY U   289                                                      
REMARK 465     SER U   290                                                      
REMARK 465     GLU U   291                                                      
REMARK 465     LYS U   292                                                      
REMARK 465     ASP U   293                                                      
REMARK 465     SER U   294                                                      
REMARK 465     ASP U   295                                                      
REMARK 465     SER U   296                                                      
REMARK 465     MET U   297                                                      
REMARK 465     GLU U   298                                                      
REMARK 465     THR U   299                                                      
REMARK 465     GLU U   300                                                      
REMARK 465     GLU U   301                                                      
REMARK 465     LYS U   302                                                      
REMARK 465     THR U   303                                                      
REMARK 465     SER U   304                                                      
REMARK 465     SER U   305                                                      
REMARK 465     ALA U   306                                                      
REMARK 465     PHE U   307                                                      
REMARK 465     VAL U   308                                                      
REMARK 465     GLY U   309                                                      
REMARK 465     LYS U   310                                                      
REMARK 465     THR U   311                                                      
REMARK 465     PRO U   312                                                      
REMARK 465     GLU U   313                                                      
REMARK 465     ALA U   314                                                      
REMARK 465     SER U   315                                                      
REMARK 465     PRO U   316                                                      
REMARK 465     GLU U   317                                                      
REMARK 465     PRO U   318                                                      
REMARK 465     LYS U   319                                                      
REMARK 465     ALA U   815                                                      
REMARK 465     PRO U   816                                                      
REMARK 465     LEU U   817                                                      
REMARK 465     GLU U   818                                                      
REMARK 465     VAL U   819                                                      
REMARK 465     PRO U   820                                                      
REMARK 465     LYS U   821                                                      
REMARK 465     GLU U   822                                                      
REMARK 465     LYS U   823                                                      
REMARK 465     GLU U   824                                                      
REMARK 465     LYS U   825                                                      
REMARK 465     GLU U   826                                                      
REMARK 465     LYS U   827                                                      
REMARK 465     VAL U   828                                                      
REMARK 465     SER U   829                                                      
REMARK 465     THR U   830                                                      
REMARK 465     ALA U   831                                                      
REMARK 465     VAL U   832                                                      
REMARK 465     LEU U   833                                                      
REMARK 465     SER U   834                                                      
REMARK 465     ILE U   835                                                      
REMARK 465     GLU U   845                                                      
REMARK 465     LYS U   846                                                      
REMARK 465     GLU U   847                                                      
REMARK 465     LYS U   848                                                      
REMARK 465     LYS U   849                                                      
REMARK 465     GLU U   850                                                      
REMARK 465     GLU U   851                                                      
REMARK 465     GLU U   852                                                      
REMARK 465     LYS U   853                                                      
REMARK 465     MET U   854                                                      
REMARK 465     GLU U   855                                                      
REMARK 465     VAL U   856                                                      
REMARK 465     ASP U   857                                                      
REMARK 465     GLU U   858                                                      
REMARK 465     ALA U   859                                                      
REMARK 465     GLU U   860                                                      
REMARK 465     LYS U   861                                                      
REMARK 465     LYS U   862                                                      
REMARK 465     GLU U   863                                                      
REMARK 465     GLU U   864                                                      
REMARK 465     LYS U   865                                                      
REMARK 465     GLU U   866                                                      
REMARK 465     LYS U   867                                                      
REMARK 465     LYS U   868                                                      
REMARK 465     LYS U   869                                                      
REMARK 465     GLU U   870                                                      
REMARK 465     PRO U   871                                                      
REMARK 465     GLU U   872                                                      
REMARK 465     PRO U   873                                                      
REMARK 465     ASN U   874                                                      
REMARK 465     PHE U   875                                                      
REMARK 465     GLN U   876                                                      
REMARK 465     LEU U   877                                                      
REMARK 465     LEU U   878                                                      
REMARK 465     ASP U   879                                                      
REMARK 465     PRO V    18                                                      
REMARK 465     PRO V    19                                                      
REMARK 465     GLY V    20                                                      
REMARK 465     GLY V    21                                                      
REMARK 465     GLY V    22                                                      
REMARK 465     GLU V    23                                                      
REMARK 465     GLN V    24                                                      
REMARK 465     GLU V    25                                                      
REMARK 465     VAL X    43                                                      
REMARK 465     GLN X    44                                                      
REMARK 465     VAL X    45                                                      
REMARK 465     LYS X    46                                                      
REMARK 465     GLU X    47                                                      
REMARK 465     GLN X    48                                                      
REMARK 465     SER X    49                                                      
REMARK 465     ILE X    50                                                      
REMARK 465     LEU X    51                                                      
REMARK 465     GLU X    52                                                      
REMARK 465     LEU X    53                                                      
REMARK 465     GLY X    54                                                      
REMARK 465     SER X    55                                                      
REMARK 465     LEU X    56                                                      
REMARK 465     LEU X    57                                                      
REMARK 465     ALA X    58                                                      
REMARK 465     LYS X    59                                                      
REMARK 465     THR X    60                                                      
REMARK 465     GLY X    61                                                      
REMARK 465     GLN X    62                                                      
REMARK 465     ALA X    63                                                      
REMARK 465     ALA X    64                                                      
REMARK 465     GLU X    65                                                      
REMARK 465     LEU X    66                                                      
REMARK 465     GLY X    67                                                      
REMARK 465     GLY X    68                                                      
REMARK 465     LEU X    69                                                      
REMARK 465     LEU X    70                                                      
REMARK 465     LYS X    71                                                      
REMARK 465     TYR X    72                                                      
REMARK 465     VAL X    73                                                      
REMARK 465     ARG X    74                                                      
REMARK 465     PRO X    75                                                      
REMARK 465     PHE X    76                                                      
REMARK 465     LEU X    77                                                      
REMARK 465     ASN X    78                                                      
REMARK 465     SER X    79                                                      
REMARK 465     ILE X    80                                                      
REMARK 465     SER X    81                                                      
REMARK 465     LYS X    82                                                      
REMARK 465     ALA X    83                                                      
REMARK 465     LYS X    84                                                      
REMARK 465     ALA X    85                                                      
REMARK 465     ALA X    86                                                      
REMARK 465     ARG X    87                                                      
REMARK 465     LEU X    88                                                      
REMARK 465     VAL X    89                                                      
REMARK 465     ARG X    90                                                      
REMARK 465     SER X    91                                                      
REMARK 465     LEU X    92                                                      
REMARK 465     LEU X    93                                                      
REMARK 465     ASP X    94                                                      
REMARK 465     LEU X    95                                                      
REMARK 465     PHE X    96                                                      
REMARK 465     LEU X    97                                                      
REMARK 465     ASP X    98                                                      
REMARK 465     MET X    99                                                      
REMARK 465     GLU X   100                                                      
REMARK 465     ALA X   101                                                      
REMARK 465     ALA X   102                                                      
REMARK 465     THR X   103                                                      
REMARK 465     GLY X   104                                                      
REMARK 465     GLN X   105                                                      
REMARK 465     GLU X   106                                                      
REMARK 465     VAL X   107                                                      
REMARK 465     GLU X   108                                                      
REMARK 465     LEU X   109                                                      
REMARK 465     CYS X   110                                                      
REMARK 465     LEU X   111                                                      
REMARK 465     GLU X   112                                                      
REMARK 465     CYS X   113                                                      
REMARK 465     ILE X   114                                                      
REMARK 465     GLU X   115                                                      
REMARK 465     TRP X   116                                                      
REMARK 465     ALA X   117                                                      
REMARK 465     LYS X   118                                                      
REMARK 465     SER X   119                                                      
REMARK 465     GLU X   120                                                      
REMARK 465     LYS X   121                                                      
REMARK 465     ARG X   122                                                      
REMARK 465     THR X   123                                                      
REMARK 465     PHE X   124                                                      
REMARK 465     LEU X   125                                                      
REMARK 465     ARG X   126                                                      
REMARK 465     GLN X   127                                                      
REMARK 465     ALA X   128                                                      
REMARK 465     LEU X   129                                                      
REMARK 465     GLU X   130                                                      
REMARK 465     ALA X   131                                                      
REMARK 465     ARG X   132                                                      
REMARK 465     LEU X   133                                                      
REMARK 465     VAL X   134                                                      
REMARK 465     SER X   135                                                      
REMARK 465     LEU X   136                                                      
REMARK 465     TYR X   137                                                      
REMARK 465     PHE X   138                                                      
REMARK 465     ASP X   139                                                      
REMARK 465     THR X   140                                                      
REMARK 465     LYS X   141                                                      
REMARK 465     ARG X   142                                                      
REMARK 465     TYR X   143                                                      
REMARK 465     GLN X   144                                                      
REMARK 465     GLU X   145                                                      
REMARK 465     ALA X   146                                                      
REMARK 465     LEU X   147                                                      
REMARK 465     HIS X   148                                                      
REMARK 465     LEU X   149                                                      
REMARK 465     GLY X   150                                                      
REMARK 465     SER X   151                                                      
REMARK 465     GLN X   152                                                      
REMARK 465     LEU X   153                                                      
REMARK 465     LEU X   154                                                      
REMARK 465     ARG X   155                                                      
REMARK 465     GLU X   156                                                      
REMARK 465     LEU X   157                                                      
REMARK 465     LYS X   158                                                      
REMARK 465     LYS X   159                                                      
REMARK 465     MET X   160                                                      
REMARK 465     ASP X   161                                                      
REMARK 465     ASP X   162                                                      
REMARK 465     LYS X   163                                                      
REMARK 465     ALA X   164                                                      
REMARK 465     LEU X   165                                                      
REMARK 465     LEU X   166                                                      
REMARK 465     VAL X   167                                                      
REMARK 465     GLU X   168                                                      
REMARK 465     VAL X   169                                                      
REMARK 465     GLN X   170                                                      
REMARK 465     LEU X   171                                                      
REMARK 465     LEU X   172                                                      
REMARK 465     GLU X   173                                                      
REMARK 465     SER X   174                                                      
REMARK 465     LYS X   175                                                      
REMARK 465     THR X   176                                                      
REMARK 465     TYR X   177                                                      
REMARK 465     HIS X   178                                                      
REMARK 465     ALA X   179                                                      
REMARK 465     LEU X   180                                                      
REMARK 465     SER X   181                                                      
REMARK 465     SER c   235                                                      
REMARK 465     GLU c   236                                                      
REMARK 465     HIS c   237                                                      
REMARK 465     CYS c   238                                                      
REMARK 465     LYS c   239                                                      
REMARK 465     HIS c   240                                                      
REMARK 465     ASN c   241                                                      
REMARK 465     GLU c   242                                                      
REMARK 465     SER c   243                                                      
REMARK 465     LEU e    10                                                      
REMARK 465     GLY e    11                                                      
REMARK 465     LEU e    12                                                      
REMARK 465     LEU e    13                                                      
REMARK 465     GLU e    14                                                      
REMARK 465     GLU e    15                                                      
REMARK 465     ASP e    16                                                      
REMARK 465     ASP e    17                                                      
REMARK 465     GLU e    18                                                      
REMARK 465     PHE e    19                                                      
REMARK 465     GLU e    20                                                      
REMARK 465     GLU e    21                                                      
REMARK 465     PHE e    22                                                      
REMARK 465     PRO e    23                                                      
REMARK 465     ALA e    24                                                      
REMARK 465     GLU e    25                                                      
REMARK 465     ASP e    26                                                      
REMARK 465     TRP e    27                                                      
REMARK 465     ALA e    28                                                      
REMARK 465     GLY e    29                                                      
REMARK 465     LEU e    30                                                      
REMARK 465     ASP e    31                                                      
REMARK 465     GLU e    32                                                      
REMARK 465     ASP e    33                                                      
REMARK 465     GLU e    34                                                      
REMARK 465     ASP e    35                                                      
REMARK 465     ALA e    36                                                      
REMARK 465     HIS e    37                                                      
REMARK 465     VAL e    38                                                      
REMARK 465     TRP e    39                                                      
REMARK 465     SER G     5                                                      
REMARK 465     GLU H     3                                                      
REMARK 465     ARG H     4                                                      
REMARK 465     SER I     2                                                      
REMARK 465     ARG I     3                                                      
REMARK 465     LYS J   241                                                      
REMARK 465     LYS J   242                                                      
REMARK 465     LYS J   243                                                      
REMARK 465     GLN J   244                                                      
REMARK 465     ALA K   128                                                      
REMARK 465     ASP K   129                                                      
REMARK 465     PRO K   130                                                      
REMARK 465     GLY K   131                                                      
REMARK 465     ALA K   132                                                      
REMARK 465     MET K   133                                                      
REMARK 465     SER M     1                                                      
REMARK 465     SER M     2                                                      
REMARK 465     ILE M     3                                                      
REMARK 465     GLY M     4                                                      
REMARK 465     GLU M   245                                                      
REMARK 465     LYS j   241                                                      
REMARK 465     LYS j   242                                                      
REMARK 465     LYS j   243                                                      
REMARK 465     GLN j   244                                                      
REMARK 465     ALA k   128                                                      
REMARK 465     ASP k   129                                                      
REMARK 465     PRO k   130                                                      
REMARK 465     GLY k   131                                                      
REMARK 465     ALA k   132                                                      
REMARK 465     MET k   133                                                      
REMARK 465     SER m     1                                                      
REMARK 465     SER m     2                                                      
REMARK 465     ILE m     3                                                      
REMARK 465     GLY m     4                                                      
REMARK 465     GLU m   245                                                      
REMARK 465     THR A    35                                                      
REMARK 465     TYR A    36                                                      
REMARK 465     GLY A    37                                                      
REMARK 465     GLN A    38                                                      
REMARK 465     SER A    39                                                      
REMARK 465     THR A    40                                                      
REMARK 465     TYR A    41                                                      
REMARK 465     SER A    42                                                      
REMARK 465     ARG A    43                                                      
REMARK 465     GLN A    44                                                      
REMARK 465     ILE A    45                                                      
REMARK 465     LYS A    46                                                      
REMARK 465     GLN A    47                                                      
REMARK 465     VAL A    48                                                      
REMARK 465     GLU A    49                                                      
REMARK 465     ASP A    50                                                      
REMARK 465     ASP A    51                                                      
REMARK 465     ILE A    52                                                      
REMARK 465     GLN A    53                                                      
REMARK 465     GLN A    54                                                      
REMARK 465     LEU A    55                                                      
REMARK 465     LEU A    56                                                      
REMARK 465     LYS A    57                                                      
REMARK 465     LYS A    58                                                      
REMARK 465     ILE A    59                                                      
REMARK 465     ASN A    60                                                      
REMARK 465     GLU A    61                                                      
REMARK 465     LEU A    62                                                      
REMARK 465     THR A    63                                                      
REMARK 465     GLY A    64                                                      
REMARK 465     ILE A    65                                                      
REMARK 465     LYS A    66                                                      
REMARK 465     GLU A    67                                                      
REMARK 465     SER A    68                                                      
REMARK 465     ASP A    69                                                      
REMARK 465     THR A    70                                                      
REMARK 465     GLY A    71                                                      
REMARK 465     LEU A    72                                                      
REMARK 465     ALA A    73                                                      
REMARK 465     PRO A    74                                                      
REMARK 465     PRO A    75                                                      
REMARK 465     ALA A    76                                                      
REMARK 465     LEU A    77                                                      
REMARK 465     TRP A    78                                                      
REMARK 465     ASP A    79                                                      
REMARK 465     LEU A    80                                                      
REMARK 465     MET A   163                                                      
REMARK 465     MET A   164                                                      
REMARK 465     GLN A   165                                                      
REMARK 465     VAL A   166                                                      
REMARK 465     GLU A   167                                                      
REMARK 465     GLU A   168                                                      
REMARK 465     LYS A   169                                                      
REMARK 465     PRO A   170                                                      
REMARK 465     ASP A   171                                                      
REMARK 465     VAL A   172                                                      
REMARK 465     THR A   173                                                      
REMARK 465     VAL B    52                                                      
REMARK 465     THR B    53                                                      
REMARK 465     PRO B    54                                                      
REMARK 465     HIS B    55                                                      
REMARK 465     THR B    56                                                      
REMARK 465     GLN B    57                                                      
REMARK 465     CYS B    58                                                      
REMARK 465     ARG B    59                                                      
REMARK 465     LEU B    60                                                      
REMARK 465     LYS B    61                                                      
REMARK 465     LEU B    62                                                      
REMARK 465     LEU B    63                                                      
REMARK 465     LYS B    64                                                      
REMARK 465     LEU B    65                                                      
REMARK 465     GLU B    66                                                      
REMARK 465     ARG B    67                                                      
REMARK 465     ILE B    68                                                      
REMARK 465     LYS B    69                                                      
REMARK 465     ASP B    70                                                      
REMARK 465     TYR B    71                                                      
REMARK 465     LEU B    72                                                      
REMARK 465     LEU B    73                                                      
REMARK 465     MET B    74                                                      
REMARK 465     GLU B    75                                                      
REMARK 465     GLU B    76                                                      
REMARK 465     GLU B    77                                                      
REMARK 465     PHE B    78                                                      
REMARK 465     ILE B    79                                                      
REMARK 465     ARG B    80                                                      
REMARK 465     ASN B    81                                                      
REMARK 465     GLN B    82                                                      
REMARK 465     GLU B    83                                                      
REMARK 465     GLN B    84                                                      
REMARK 465     MET B    85                                                      
REMARK 465     LYS B    86                                                      
REMARK 465     PRO B    87                                                      
REMARK 465     LEU B    88                                                      
REMARK 465     GLU B    89                                                      
REMARK 465     GLU B    90                                                      
REMARK 465     LEU C    11                                                      
REMARK 465     GLU C    12                                                      
REMARK 465     GLU C    13                                                      
REMARK 465     GLY C    14                                                      
REMARK 465     LYS C    15                                                      
REMARK 465     ALA C    16                                                      
REMARK 465     GLY C    17                                                      
REMARK 465     SER C    18                                                      
REMARK 465     GLY C    19                                                      
REMARK 465     LEU C    20                                                      
REMARK 465     ARG C    21                                                      
REMARK 465     GLN C    22                                                      
REMARK 465     TYR C    23                                                      
REMARK 465     ILE C   251                                                      
REMARK 465     ASP C   252                                                      
REMARK 465     SER C   253                                                      
REMARK 465     ILE C   254                                                      
REMARK 465     GLY C   255                                                      
REMARK 465     SER C   256                                                      
REMARK 465     SER C   257                                                      
REMARK 465     ARG C   258                                                      
REMARK 465     LEU C   259                                                      
REMARK 465     GLU C   260                                                      
REMARK 465     GLY C   261                                                      
REMARK 465     GLY C   262                                                      
REMARK 465     SER C   263                                                      
REMARK 465     GLY C   264                                                      
REMARK 465     GLY C   265                                                      
REMARK 465     ASP C   266                                                      
REMARK 465     ASP F   100                                                      
REMARK 465     PRO F   101                                                      
REMARK 465     ASN F   102                                                      
REMARK 465     ASP F   103                                                      
REMARK 465     GLN F   104                                                      
REMARK 465     GLU F   105                                                      
REMARK 465     GLU F   106                                                      
REMARK 465     ASP F   107                                                      
REMARK 465     GLY F   108                                                      
REMARK 465     ALA F   109                                                      
REMARK 465     ASN F   110                                                      
REMARK 465     ILE F   111                                                      
REMARK 465     ASP F   112                                                      
REMARK 465     LEU F   113                                                      
REMARK 465     ASP F   114                                                      
REMARK 465     SER F   115                                                      
REMARK 465     GLN F   116                                                      
REMARK 465     ARG F   117                                                      
REMARK 465     LYS F   118                                                      
REMARK 465     GLY F   119                                                      
REMARK 465     MET f     1                                                      
REMARK 465     GLU f     2                                                      
REMARK 465     GLU f     3                                                      
REMARK 465     GLY f     4                                                      
REMARK 465     GLY f     5                                                      
REMARK 465     LEU f    56                                                      
REMARK 465     GLU f    57                                                      
REMARK 465     MET f    58                                                      
REMARK 465     LEU f    59                                                      
REMARK 465     VAL f    60                                                      
REMARK 465     GLU f    61                                                      
REMARK 465     ARG f    62                                                      
REMARK 465     LEU f    63                                                      
REMARK 465     GLY f    64                                                      
REMARK 465     GLU f    65                                                      
REMARK 465     LYS f    66                                                      
REMARK 465     ASP f    67                                                      
REMARK 465     THR f    68                                                      
REMARK 465     SER f    69                                                      
REMARK 465     GLY f   104                                                      
REMARK 465     LYS f   105                                                      
REMARK 465     LEU f   106                                                      
REMARK 465     LYS f   107                                                      
REMARK 465     GLU f   108                                                      
REMARK 465     ILE f   109                                                      
REMARK 465     TYR f   110                                                      
REMARK 465     GLU f   111                                                      
REMARK 465     ASN f   112                                                      
REMARK 465     MET f   113                                                      
REMARK 465     ALA f   114                                                      
REMARK 465     PRO f   115                                                      
REMARK 465     GLY f   116                                                      
REMARK 465     GLU f   117                                                      
REMARK 465     SER f   147                                                      
REMARK 465     GLN f   148                                                      
REMARK 465     GLU f   149                                                      
REMARK 465     GLU f   150                                                      
REMARK 465     LEU f   151                                                      
REMARK 465     ALA f   152                                                      
REMARK 465     SER f   153                                                      
REMARK 465     TRP f   154                                                      
REMARK 465     GLY f   155                                                      
REMARK 465     HIS f   156                                                      
REMARK 465     GLU f   157                                                      
REMARK 465     TYR f   158                                                      
REMARK 465     VAL f   159                                                      
REMARK 465     ARG f   160                                                      
REMARK 465     HIS f   161                                                      
REMARK 465     LEU f   162                                                      
REMARK 465     TYR f   194                                                      
REMARK 465     ASN f   195                                                      
REMARK 465     MET f   196                                                      
REMARK 465     ALA f   197                                                      
REMARK 465     HIS f   198                                                      
REMARK 465     ASN f   199                                                      
REMARK 465     ALA f   200                                                      
REMARK 465     GLU f   201                                                      
REMARK 465     HIS f   202                                                      
REMARK 465     GLU f   203                                                      
REMARK 465     ALA f   204                                                      
REMARK 465     CYS f   205                                                      
REMARK 465     ASP f   206                                                      
REMARK 465     VAL f   290                                                      
REMARK 465     GLN f   291                                                      
REMARK 465     LYS f   292                                                      
REMARK 465     GLN f   293                                                      
REMARK 465     MET f   294                                                      
REMARK 465     ALA f   295                                                      
REMARK 465     PHE f   296                                                      
REMARK 465     ALA f   383                                                      
REMARK 465     ALA f   384                                                      
REMARK 465     PHE f   385                                                      
REMARK 465     GLY f   386                                                      
REMARK 465     SER f   700                                                      
REMARK 465     ASN f   701                                                      
REMARK 465     PRO f   702                                                      
REMARK 465     ARG f   703                                                      
REMARK 465     LEU f   704                                                      
REMARK 465     ASN f   705                                                      
REMARK 465     ILE f   706                                                      
REMARK 465     LEU f   707                                                      
REMARK 465     ASP f   708                                                      
REMARK 465     THR f   709                                                      
REMARK 465     LEU f   710                                                      
REMARK 465     SER f   711                                                      
REMARK 465     LYS f   712                                                      
REMARK 465     PHE f   713                                                      
REMARK 465     MET f   729                                                      
REMARK 465     GLY f   730                                                      
REMARK 465     MET f   731                                                      
REMARK 465     VAL f   732                                                      
REMARK 465     GLY f   733                                                      
REMARK 465     SER f   734                                                      
REMARK 465     GLY f   735                                                      
REMARK 465     THR f   736                                                      
REMARK 465     ASN f   737                                                      
REMARK 465     ASN f   738                                                      
REMARK 465     ASP f   755                                                      
REMARK 465     PRO f   756                                                      
REMARK 465     ASN f   757                                                      
REMARK 465     ASN f   758                                                      
REMARK 465     LEU f   759                                                      
REMARK 465     PHE f   760                                                      
REMARK 465     MET f   761                                                      
REMARK 465     VAL f   762                                                      
REMARK 465     ARG f   763                                                      
REMARK 465     LEU f   764                                                      
REMARK 465     ALA f   765                                                      
REMARK 465     GLN f   766                                                      
REMARK 465     GLY f   767                                                      
REMARK 465     LEU f   768                                                      
REMARK 465     THR f   769                                                      
REMARK 465     HIS f   770                                                      
REMARK 465     LEU f   771                                                      
REMARK 465     GLY f   772                                                      
REMARK 465     ASP f   805                                                      
REMARK 465     VAL f   806                                                      
REMARK 465     ARG f   807                                                      
REMARK 465     ASN f   808                                                      
REMARK 465     ILE f   809                                                      
REMARK 465     ILE f   810                                                      
REMARK 465     LEU f   811                                                      
REMARK 465     GLY f   812                                                      
REMARK 465     LYS f   813                                                      
REMARK 465     SER f   814                                                      
REMARK 465     HIS f   815                                                      
REMARK 465     TYR f   816                                                      
REMARK 465     VAL f   817                                                      
REMARK 465     LEU f   818                                                      
REMARK 465     TYR f   819                                                      
REMARK 465     GLY f   820                                                      
REMARK 465     LEU f   821                                                      
REMARK 465     VAL f   822                                                      
REMARK 465     ALA f   823                                                      
REMARK 465     ALA f   824                                                      
REMARK 465     MET f   825                                                      
REMARK 465     GLN f   826                                                      
REMARK 465     PRO f   827                                                      
REMARK 465     ARG f   828                                                      
REMARK 465     MET f   829                                                      
REMARK 465     LEU f   830                                                      
REMARK 465     VAL f   831                                                      
REMARK 465     THR f   832                                                      
REMARK 465     PHE f   833                                                      
REMARK 465     ASP f   834                                                      
REMARK 465     GLU f   835                                                      
REMARK 465     GLU f   836                                                      
REMARK 465     LEU f   837                                                      
REMARK 465     ARG f   838                                                      
REMARK 465     PRO f   839                                                      
REMARK 465     LEU f   840                                                      
REMARK 465     PRO f   841                                                      
REMARK 465     VAL f   842                                                      
REMARK 465     SER f   843                                                      
REMARK 465     VAL f   844                                                      
REMARK 465     ARG f   845                                                      
REMARK 465     VAL f   846                                                      
REMARK 465     GLY f   847                                                      
REMARK 465     GLN f   848                                                      
REMARK 465     ALA f   849                                                      
REMARK 465     VAL f   850                                                      
REMARK 465     ASP f   851                                                      
REMARK 465     VAL f   852                                                      
REMARK 465     VAL f   853                                                      
REMARK 465     GLY f   854                                                      
REMARK 465     GLN f   855                                                      
REMARK 465     ALA f   856                                                      
REMARK 465     GLY f   857                                                      
REMARK 465     LYS f   858                                                      
REMARK 465     PRO f   859                                                      
REMARK 465     LYS f   860                                                      
REMARK 465     THR f   861                                                      
REMARK 465     ILE f   862                                                      
REMARK 465     THR f   863                                                      
REMARK 465     GLY f   864                                                      
REMARK 465     PHE f   865                                                      
REMARK 465     GLN f   866                                                      
REMARK 465     THR f   867                                                      
REMARK 465     HIS f   868                                                      
REMARK 465     THR f   869                                                      
REMARK 465     THR f   870                                                      
REMARK 465     PRO f   871                                                      
REMARK 465     VAL f   872                                                      
REMARK 465     LEU f   873                                                      
REMARK 465     LEU f   874                                                      
REMARK 465     ALA f   875                                                      
REMARK 465     HIS f   876                                                      
REMARK 465     GLY f   877                                                      
REMARK 465     GLU f   878                                                      
REMARK 465     ARG f   879                                                      
REMARK 465     ALA f   880                                                      
REMARK 465     GLU f   881                                                      
REMARK 465     LEU f   882                                                      
REMARK 465     ALA f   883                                                      
REMARK 465     THR f   884                                                      
REMARK 465     GLU f   885                                                      
REMARK 465     GLU f   886                                                      
REMARK 465     PHE f   887                                                      
REMARK 465     LEU f   888                                                      
REMARK 465     PRO f   889                                                      
REMARK 465     VAL f   890                                                      
REMARK 465     THR f   891                                                      
REMARK 465     PRO f   892                                                      
REMARK 465     ILE f   893                                                      
REMARK 465     LEU f   894                                                      
REMARK 465     GLU f   895                                                      
REMARK 465     GLY f   896                                                      
REMARK 465     PHE f   897                                                      
REMARK 465     VAL f   898                                                      
REMARK 465     ILE f   899                                                      
REMARK 465     LEU f   900                                                      
REMARK 465     ARG f   901                                                      
REMARK 465     LYS f   902                                                      
REMARK 465     ASN f   903                                                      
REMARK 465     PRO f   904                                                      
REMARK 465     ASN f   905                                                      
REMARK 465     TYR f   906                                                      
REMARK 465     ASP f   907                                                      
REMARK 465     LEU f   908                                                      
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470     LYS G  45    CG   CD   CE   NZ                                   
REMARK 470     ASP G  46    CG   OD1  OD2                                       
REMARK 470     LYS G  55    CG   CD   CE   NZ                                   
REMARK 470     LYS G  59    CG   CD   CE   NZ                                   
REMARK 470     SER G  63    OG                                                  
REMARK 470     GLU G 146    CG   CD   OE1  OE2                                  
REMARK 470     LYS G 181    CG   CD   CE   NZ                                   
REMARK 470     LYS G 186    CG   CD   CE   NZ                                   
REMARK 470     PHE G 187    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP G 188    CG   OD1  OD2                                       
REMARK 470     GLU G 196    CG   CD   OE1  OE2                                  
REMARK 470     GLU G 223    CG   CD   OE1  OE2                                  
REMARK 470     LYS H  18    CG   CD   CE   NZ                                   
REMARK 470     VAL H  36    CG1  CG2                                            
REMARK 470     GLN H  52    CG   CD   OE1  NE2                                  
REMARK 470     LYS H  53    CG   CD   CE   NZ                                   
REMARK 470     SER H  54    OG                                                  
REMARK 470     ILE H  55    CG1  CG2  CD1                                       
REMARK 470     ARG H  60    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TRP H 139    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP H 139    CZ3  CH2                                            
REMARK 470     ASN H 140    CG   OD1  ND2                                       
REMARK 470     GLU H 141    CG   CD   OE1  OE2                                  
REMARK 470     ARG H 143    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     MET H 163    CG   SD   CE                                        
REMARK 470     LYS H 176    CG   CD   CE   NZ                                   
REMARK 470     ARG H 177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR H 178    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU H 184    CG   CD1  CD2                                       
REMARK 470     LEU H 193    CG   CD1  CD2                                       
REMARK 470     LEU H 195    CG   CD1  CD2                                       
REMARK 470     LYS H 196    CG   CD   CE   NZ                                   
REMARK 470     PHE H 199    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU H 200    CG   CD   OE1  OE2                                  
REMARK 470     GLN H 202    CG   CD   OE1  NE2                                  
REMARK 470     VAL H 226    CG1  CG2                                            
REMARK 470     LYS H 227    CG   CD   CE   NZ                                   
REMARK 470     LEU H 230    CG   CD1  CD2                                       
REMARK 470     ILE H 233    CG1  CG2  CD1                                       
REMARK 470     SER I  13    OG                                                  
REMARK 470     ILE I  37    CG1  CG2  CD1                                       
REMARK 470     ASN I  51    CG   OD1  ND2                                       
REMARK 470     ILE I  52    CG1  CG2  CD1                                       
REMARK 470     LYS I  54    CG   CD   CE   NZ                                   
REMARK 470     GLN I 177    CG   CD   OE1  NE2                                  
REMARK 470     MET I 184    CG   SD   CE                                        
REMARK 470     ILE I 194    CG1  CG2  CD1                                       
REMARK 470     MET I 201    CG   SD   CE                                        
REMARK 470     LYS I 205    CG   CD   CE   NZ                                   
REMARK 470     LYS I 210    CG   CD   CE   NZ                                   
REMARK 470     LYS I 222    CG   CD   CE   NZ                                   
REMARK 470     LYS I 229    CG   CD   CE   NZ                                   
REMARK 470     GLN I 230    CG   CD   OE1  NE2                                  
REMARK 470     LYS I 231    CG   CD   CE   NZ                                   
REMARK 470     GLU I 250    CG   CD   OE1  OE2                                  
REMARK 470     LYS I 251    CG   CD   CE   NZ                                   
REMARK 470     LYS J  27    CG   CD   CE   NZ                                   
REMARK 470     ILE J  40    CG1  CG2  CD1                                       
REMARK 470     VAL J  42    CG1  CG2                                            
REMARK 470     GLU J  46    CG   CD   OE1  OE2                                  
REMARK 470     LYS J  47    CG   CD   CE   NZ                                   
REMARK 470     LYS J  48    CG   CD   CE   NZ                                   
REMARK 470     SER J  49    OG                                                  
REMARK 470     VAL J  50    CG1  CG2                                            
REMARK 470     LEU J  53    CG   CD1  CD2                                       
REMARK 470     PHE J 136    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE J 138    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR J 141    OG1  CG2                                            
REMARK 470     LYS J 157    CG   CD   CE   NZ                                   
REMARK 470     ARG J 163    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS J 166    CG   CD   CE   NZ                                   
REMARK 470     ARG J 169    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU J 170    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 174    CG   CD   CE   NZ                                   
REMARK 470     ILE J 181    CG1  CG2  CD1                                       
REMARK 470     GLU J 182    CG   CD   OE1  OE2                                  
REMARK 470     THR J 183    OG1  CG2                                            
REMARK 470     ASP J 185    CG   OD1  OD2                                       
REMARK 470     THR J 187    OG1  CG2                                            
REMARK 470     LYS J 189    CG   CD   CE   NZ                                   
REMARK 470     ILE J 192    CG1  CG2  CD1                                       
REMARK 470     LYS J 193    CG   CD   CE   NZ                                   
REMARK 470     LEU J 195    CG   CD1  CD2                                       
REMARK 470     LEU J 196    CG   CD1  CD2                                       
REMARK 470     GLU J 197    CG   CD   OE1  OE2                                  
REMARK 470     VAL J 198    CG1  CG2                                            
REMARK 470     VAL J 199    CG1  CG2                                            
REMARK 470     LYS J 204    CG   CD   CE   NZ                                   
REMARK 470     GLU J 207    CG   CD   OE1  OE2                                  
REMARK 470     LEU J 208    CG   CD1  CD2                                       
REMARK 470     ARG J 212    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG J 213    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER J 216    OG                                                  
REMARK 470     LYS J 218    CG   CD   CE   NZ                                   
REMARK 470     GLU J 223    CG   CD   OE1  OE2                                  
REMARK 470     ILE J 225    CG1  CG2  CD1                                       
REMARK 470     GLU J 226    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 227    CG   CD   CE   NZ                                   
REMARK 470     VAL J 229    CG1  CG2                                            
REMARK 470     ILE J 232    CG1  CG2  CD1                                       
REMARK 470     GLU J 233    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 234    CG   CD   CE   NZ                                   
REMARK 470     GLU J 235    CG   CD   OE1  OE2                                  
REMARK 470     LYS J 236    CG   CD   CE   NZ                                   
REMARK 470     GLU J 237    CG   CD   OE1  OE2                                  
REMARK 470     ASN J 239    CG   OD1  ND2                                       
REMARK 470     GLU J 240    CG   CD   OE1  OE2                                  
REMARK 470     LYS K  86    CG   CD   CE   NZ                                   
REMARK 470     LYS K 187    CG   CD   CE   NZ                                   
REMARK 470     LYS K 192    CG   CD   CE   NZ                                   
REMARK 470     GLU K 208    CG   CD   OE1  OE2                                  
REMARK 470     LYS K 209    CG   CD   CE   NZ                                   
REMARK 470     LYS K 231    CG   CD   CE   NZ                                   
REMARK 470     LYS L 208    CG   CD   CE   NZ                                   
REMARK 470     LYS L 217    CG   CD   CE   NZ                                   
REMARK 470     ASP L 218    CG   OD1  OD2                                       
REMARK 470     GLU L 237    CG   CD   OE1  OE2                                  
REMARK 470     GLU L 238    CG   CD   OE1  OE2                                  
REMARK 470     GLN L 241    CG   CD   OE1  NE2                                  
REMARK 470     LYS M 109    CG   CD   CE   NZ                                   
REMARK 470     ASN M 143    CG   OD1  ND2                                       
REMARK 470     GLU M 203    CG   CD   OE1  OE2                                  
REMARK 470     LYS M 205    CG   CD   CE   NZ                                   
REMARK 470     LYS M 207    CG   CD   CE   NZ                                   
REMARK 470     ARG M 223    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS O   9    CG   CD   CE   NZ                                   
REMARK 470     LYS O 180    CG   CD   CE   NZ                                   
REMARK 470     LYS O 206    CG   CD   CE   NZ                                   
REMARK 470     GLU O 214    CG   CD   OE1  OE2                                  
REMARK 470     ARG P  48    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS Q  41    CG   CD   CE   NZ                                   
REMARK 470     ARG Q  95    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU Q 109    CG   CD   OE1  OE2                                  
REMARK 470     LYS Q 185    CG   CD   CE   NZ                                   
REMARK 470     LYS Q 198    CG   CD   CE   NZ                                   
REMARK 470     GLN Q 199    CG   CD   OE1  NE2                                  
REMARK 470     LYS R 106    CG   CD   CE   NZ                                   
REMARK 470     GLU R 150    CG   CD   OE1  OE2                                  
REMARK 470     ILE R 185    CG1  CG2  CD1                                       
REMARK 470     LYS S  45    CG   CD   CE   NZ                                   
REMARK 470     VAL S 161    CG1  CG2                                            
REMARK 470     LEU S 166    CG   CD1  CD2                                       
REMARK 470     LYS S 200    CG   CD   CE   NZ                                   
REMARK 470     ARG T  44    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS T 156    CG   CD   CE   NZ                                   
REMARK 470     LYS T 195    CG   CD   CE   NZ                                   
REMARK 470     LYS g  45    CG   CD   CE   NZ                                   
REMARK 470     ASP g  46    CG   OD1  OD2                                       
REMARK 470     LYS g  55    CG   CD   CE   NZ                                   
REMARK 470     LYS g  59    CG   CD   CE   NZ                                   
REMARK 470     SER g  63    OG                                                  
REMARK 470     GLU g 146    CG   CD   OE1  OE2                                  
REMARK 470     LYS g 181    CG   CD   CE   NZ                                   
REMARK 470     LYS g 186    CG   CD   CE   NZ                                   
REMARK 470     PHE g 187    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     ASP g 188    CG   OD1  OD2                                       
REMARK 470     GLU g 196    CG   CD   OE1  OE2                                  
REMARK 470     GLU g 223    CG   CD   OE1  OE2                                  
REMARK 470     LYS h  18    CG   CD   CE   NZ                                   
REMARK 470     VAL h  36    CG1  CG2                                            
REMARK 470     GLN h  52    CG   CD   OE1  NE2                                  
REMARK 470     LYS h  53    CG   CD   CE   NZ                                   
REMARK 470     SER h  54    OG                                                  
REMARK 470     ILE h  55    CG1  CG2  CD1                                       
REMARK 470     ARG h  60    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TRP h 139    CG   CD1  CD2  NE1  CE2  CE3  CZ2                   
REMARK 470     TRP h 139    CZ3  CH2                                            
REMARK 470     ASN h 140    CG   OD1  ND2                                       
REMARK 470     GLU h 141    CG   CD   OE1  OE2                                  
REMARK 470     ARG h 143    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     MET h 163    CG   SD   CE                                        
REMARK 470     LYS h 176    CG   CD   CE   NZ                                   
REMARK 470     ARG h 177    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     TYR h 178    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LEU h 184    CG   CD1  CD2                                       
REMARK 470     LEU h 193    CG   CD1  CD2                                       
REMARK 470     LEU h 195    CG   CD1  CD2                                       
REMARK 470     LYS h 196    CG   CD   CE   NZ                                   
REMARK 470     PHE h 199    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     GLU h 200    CG   CD   OE1  OE2                                  
REMARK 470     GLN h 202    CG   CD   OE1  NE2                                  
REMARK 470     VAL h 226    CG1  CG2                                            
REMARK 470     LYS h 227    CG   CD   CE   NZ                                   
REMARK 470     LEU h 230    CG   CD1  CD2                                       
REMARK 470     ILE h 233    CG1  CG2  CD1                                       
REMARK 470     SER i  13    OG                                                  
REMARK 470     ILE i  37    CG1  CG2  CD1                                       
REMARK 470     ASN i  51    CG   OD1  ND2                                       
REMARK 470     ILE i  52    CG1  CG2  CD1                                       
REMARK 470     LYS i  54    CG   CD   CE   NZ                                   
REMARK 470     GLN i 177    CG   CD   OE1  NE2                                  
REMARK 470     MET i 184    CG   SD   CE                                        
REMARK 470     ILE i 194    CG1  CG2  CD1                                       
REMARK 470     MET i 201    CG   SD   CE                                        
REMARK 470     LYS i 205    CG   CD   CE   NZ                                   
REMARK 470     LYS i 210    CG   CD   CE   NZ                                   
REMARK 470     LYS i 222    CG   CD   CE   NZ                                   
REMARK 470     LYS i 229    CG   CD   CE   NZ                                   
REMARK 470     GLN i 230    CG   CD   OE1  NE2                                  
REMARK 470     LYS i 231    CG   CD   CE   NZ                                   
REMARK 470     GLU i 250    CG   CD   OE1  OE2                                  
REMARK 470     LYS i 251    CG   CD   CE   NZ                                   
REMARK 470     LYS j  27    CG   CD   CE   NZ                                   
REMARK 470     ILE j  40    CG1  CG2  CD1                                       
REMARK 470     VAL j  42    CG1  CG2                                            
REMARK 470     GLU j  46    CG   CD   OE1  OE2                                  
REMARK 470     LYS j  47    CG   CD   CE   NZ                                   
REMARK 470     LYS j  48    CG   CD   CE   NZ                                   
REMARK 470     SER j  49    OG                                                  
REMARK 470     VAL j  50    CG1  CG2                                            
REMARK 470     LEU j  53    CG   CD1  CD2                                       
REMARK 470     PHE j 136    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     PHE j 138    CG   CD1  CD2  CE1  CE2  CZ                         
REMARK 470     THR j 141    OG1  CG2                                            
REMARK 470     LYS j 157    CG   CD   CE   NZ                                   
REMARK 470     ARG j 163    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS j 166    CG   CD   CE   NZ                                   
REMARK 470     ARG j 169    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU j 170    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 174    CG   CD   CE   NZ                                   
REMARK 470     ILE j 181    CG1  CG2  CD1                                       
REMARK 470     GLU j 182    CG   CD   OE1  OE2                                  
REMARK 470     THR j 183    OG1  CG2                                            
REMARK 470     ASP j 185    CG   OD1  OD2                                       
REMARK 470     THR j 187    OG1  CG2                                            
REMARK 470     LYS j 189    CG   CD   CE   NZ                                   
REMARK 470     ILE j 192    CG1  CG2  CD1                                       
REMARK 470     LYS j 193    CG   CD   CE   NZ                                   
REMARK 470     LEU j 195    CG   CD1  CD2                                       
REMARK 470     LEU j 196    CG   CD1  CD2                                       
REMARK 470     GLU j 197    CG   CD   OE1  OE2                                  
REMARK 470     VAL j 198    CG1  CG2                                            
REMARK 470     VAL j 199    CG1  CG2                                            
REMARK 470     LYS j 204    CG   CD   CE   NZ                                   
REMARK 470     GLU j 207    CG   CD   OE1  OE2                                  
REMARK 470     LEU j 208    CG   CD1  CD2                                       
REMARK 470     ARG j 212    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     ARG j 213    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     SER j 216    OG                                                  
REMARK 470     LYS j 218    CG   CD   CE   NZ                                   
REMARK 470     GLU j 223    CG   CD   OE1  OE2                                  
REMARK 470     ILE j 225    CG1  CG2  CD1                                       
REMARK 470     GLU j 226    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 227    CG   CD   CE   NZ                                   
REMARK 470     VAL j 229    CG1  CG2                                            
REMARK 470     ILE j 232    CG1  CG2  CD1                                       
REMARK 470     GLU j 233    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 234    CG   CD   CE   NZ                                   
REMARK 470     GLU j 235    CG   CD   OE1  OE2                                  
REMARK 470     LYS j 236    CG   CD   CE   NZ                                   
REMARK 470     GLU j 237    CG   CD   OE1  OE2                                  
REMARK 470     ASN j 239    CG   OD1  ND2                                       
REMARK 470     GLU j 240    CG   CD   OE1  OE2                                  
REMARK 470     TYR k   8    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     LYS k  86    CG   CD   CE   NZ                                   
REMARK 470     LYS k 187    CG   CD   CE   NZ                                   
REMARK 470     LYS k 192    CG   CD   CE   NZ                                   
REMARK 470     GLU k 208    CG   CD   OE1  OE2                                  
REMARK 470     LYS k 209    CG   CD   CE   NZ                                   
REMARK 470     LYS k 231    CG   CD   CE   NZ                                   
REMARK 470     LYS l 208    CG   CD   CE   NZ                                   
REMARK 470     LYS l 217    CG   CD   CE   NZ                                   
REMARK 470     ASP l 218    CG   OD1  OD2                                       
REMARK 470     GLU l 237    CG   CD   OE1  OE2                                  
REMARK 470     GLU l 238    CG   CD   OE1  OE2                                  
REMARK 470     GLN l 241    CG   CD   OE1  NE2                                  
REMARK 470     LYS m 109    CG   CD   CE   NZ                                   
REMARK 470     ASN m 143    CG   OD1  ND2                                       
REMARK 470     GLU m 203    CG   CD   OE1  OE2                                  
REMARK 470     LYS m 205    CG   CD   CE   NZ                                   
REMARK 470     LYS m 207    CG   CD   CE   NZ                                   
REMARK 470     ARG m 223    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS o   9    CG   CD   CE   NZ                                   
REMARK 470     LYS o 180    CG   CD   CE   NZ                                   
REMARK 470     LYS o 206    CG   CD   CE   NZ                                   
REMARK 470     GLU o 214    CG   CD   OE1  OE2                                  
REMARK 470     ARG p  48    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS q  41    CG   CD   CE   NZ                                   
REMARK 470     ARG q  95    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU q 109    CG   CD   OE1  OE2                                  
REMARK 470     LYS q 185    CG   CD   CE   NZ                                   
REMARK 470     LYS q 198    CG   CD   CE   NZ                                   
REMARK 470     GLN q 199    CG   CD   OE1  NE2                                  
REMARK 470     LYS r 106    CG   CD   CE   NZ                                   
REMARK 470     GLU r 150    CG   CD   OE1  OE2                                  
REMARK 470     ILE r 185    CG1  CG2  CD1                                       
REMARK 470     LYS s  45    CG   CD   CE   NZ                                   
REMARK 470     VAL s 161    CG1  CG2                                            
REMARK 470     LEU s 166    CG   CD1  CD2                                       
REMARK 470     LYS s 200    CG   CD   CE   NZ                                   
REMARK 470     ARG t  44    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LYS t 156    CG   CD   CE   NZ                                   
REMARK 470     LYS t 195    CG   CD   CE   NZ                                   
REMARK 470     ASP A  83    CG   OD1  OD2                                       
REMARK 470     LYS A  84    CG   CD   CE   NZ                                   
REMARK 470     LYS A 100    NZ                                                  
REMARK 470     ARG A 144    CZ   NH1  NH2                                       
REMARK 470     LEU A 373    CD1                                                 
REMARK 470     ILE A 403    CG2                                                 
REMARK 470     LYS B  91    CG   CD   CE   NZ                                   
REMARK 470     GLN B  92    CG   CD   OE1  NE2                                  
REMARK 470     GLU B  93    CG   CD   OE1  OE2                                  
REMARK 470     GLU B  95    CG   CD   OE1  OE2                                  
REMARK 470     ARG B  96    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR B 125    CG2                                                 
REMARK 470     HIS B 157    CD2  NE2                                            
REMARK 470     GLU B 209    CG   CD   OE1  OE2                                  
REMARK 470     ASP C 100    CG   OD1  OD2                                       
REMARK 470     THR C 109    CG2                                                 
REMARK 470     THR C 210    CG2                                                 
REMARK 470     GLU C 322    CD   OE1  OE2                                       
REMARK 470     GLU C 323    CG   CD   OE1  OE2                                  
REMARK 470     MET C 385    SD   CE                                             
REMARK 470     LYS C 397    CD   CE   NZ                                        
REMARK 470     LYS E  15    CG   CD   CE   NZ                                   
REMARK 470     LEU E  16    CG   CD1  CD2                                       
REMARK 470     LEU E  17    CG   CD1  CD2                                       
REMARK 470     GLU E  18    CG   CD   OE1  OE2                                  
REMARK 470     HIS E  19    CG   ND1  CD2  CE1  NE2                             
REMARK 470     LYS E  20    CG   CD   CE   NZ                                   
REMARK 470     GLU E  21    CG   CD   OE1  OE2                                  
REMARK 470     ILE E  22    CG1  CG2  CD1                                       
REMARK 470     ASP E  23    CG   OD1  OD2                                       
REMARK 470     ARG E  25    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU E  26    CG   CD1  CD2                                       
REMARK 470     LYS E  27    CG   CD   CE   NZ                                   
REMARK 470     GLU E  28    CG   CD   OE1  OE2                                  
REMARK 470     LEU E  29    CG   CD1  CD2                                       
REMARK 470     ARG E  30    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     GLU E  31    CG   CD   OE1  OE2                                  
REMARK 470     GLN E  32    CG   CD   OE1  NE2                                  
REMARK 470     LEU E  33    CG   CD1  CD2                                       
REMARK 470     LYS E  34    CG   CD   CE   NZ                                   
REMARK 470     GLU E  35    CG   CD   OE1  OE2                                  
REMARK 470     LEU E  36    CG   CD1  CD2                                       
REMARK 470     THR E  37    OG1  CG2                                            
REMARK 470     LYS E  38    CG   CD   CE   NZ                                   
REMARK 470     GLN E  39    CG   CD   OE1  NE2                                  
REMARK 470     TYR E  40    CG   CD1  CD2  CE1  CE2  CZ   OH                    
REMARK 470     GLU E  41    CG   CD   OE1  OE2                                  
REMARK 470     LYS E  42    CG   CD   CE   NZ                                   
REMARK 470     GLU E  44    CG   CD   OE1  OE2                                  
REMARK 470     ASN E  45    CG   OD1  ND2                                       
REMARK 470     ASP E  46    CG   OD1  OD2                                       
REMARK 470     LEU E  47    CG   CD1  CD2                                       
REMARK 470     ARG F  44    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     THR F  45    OG1  CG2                                            
REMARK 470     ARG F  46    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     LEU F  47    CG   CD1  CD2                                       
REMARK 470     LEU F  48    CG   CD1  CD2                                       
REMARK 470     ASP F  49    CG   OD1  OD2                                       
REMARK 470     SER F  50    OG                                                  
REMARK 470     GLU F  51    CG   CD   OE1  OE2                                  
REMARK 470     ILE F  52    CG1  CG2  CD1                                       
REMARK 470     LYS F  53    CG   CD   CE   NZ                                   
REMARK 470     ILE F  54    CG1  CG2  CD1                                       
REMARK 470     MET F  55    CG   SD   CE                                        
REMARK 470     LYS F  56    CG   CD   CE   NZ                                   
REMARK 470     SER F  57    OG                                                  
REMARK 470     GLU F  58    CG   CD   OE1  OE2                                  
REMARK 470     VAL F  59    CG1  CG2                                            
REMARK 470     LEU F  60    CG   CD1  CD2                                       
REMARK 470     ARG F  61    CG   CD   NE   CZ   NH1  NH2                        
REMARK 470     VAL F  62    CG1  CG2                                            
REMARK 470     THR F  63    OG1  CG2                                            
REMARK 470     HIS F  64    CG   ND1  CD2  CE1  NE2                             
REMARK 470     GLU F  65    CG   CD   OE1  OE2                                  
REMARK 470     LEU F  66    CG   CD1  CD2                                       
REMARK 470     GLN F  67    CG   CD   OE1  NE2                                  
REMARK 470     MET F  69    CG   SD   CE                                        
REMARK 470     LYS F  70    CG   CD   CE   NZ                                   
REMARK 470     ASP F  71    CG   OD1  OD2                                       
REMARK 470     THR F 416    CG2                                                 
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   O    SER f   363     N    VAL f   365              2.04            
REMARK 500   CD   ARG f   494     OD1  ASP f   496              2.06            
REMARK 500   O    GLY D   372     N6   AGS D   501              2.09            
REMARK 500   O    VAL f   311     O    ALA f   490              2.09            
REMARK 500   O    GLY F   230     C8   AGS F   501              2.11            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    LEU U  24   CA  -  CB  -  CG  ANGL. DEV. =  15.3 DEGREES          
REMARK 500    LEU V 170   CA  -  CB  -  CG  ANGL. DEV. =  15.7 DEGREES          
REMARK 500    LEU V 332   CA  -  CB  -  CG  ANGL. DEV. =  14.5 DEGREES          
REMARK 500    LEU V 357   CA  -  CB  -  CG  ANGL. DEV. =  14.2 DEGREES          
REMARK 500    LEU Y 287   CA  -  CB  -  CG  ANGL. DEV. =  15.8 DEGREES          
REMARK 500    LEU Z 121   CA  -  CB  -  CG  ANGL. DEV. =  15.8 DEGREES          
REMARK 500    LEU Z 176   CA  -  CB  -  CG  ANGL. DEV. =  18.9 DEGREES          
REMARK 500    LEU Z 251   CA  -  CB  -  CG  ANGL. DEV. =  17.2 DEGREES          
REMARK 500    ASP c 279   C   -  N   -  CA  ANGL. DEV. =  21.3 DEGREES          
REMARK 500    LEU e  56   CA  -  CB  -  CG  ANGL. DEV. =  16.5 DEGREES          
REMARK 500    LEU H 110   CA  -  CB  -  CG  ANGL. DEV. =  14.4 DEGREES          
REMARK 500    TYR J   3   C   -  N   -  CA  ANGL. DEV. =  16.7 DEGREES          
REMARK 500    ARG J   5   NE  -  CZ  -  NH2 ANGL. DEV. =  -3.3 DEGREES          
REMARK 500    PHE K  22   C   -  N   -  CA  ANGL. DEV. =  17.9 DEGREES          
REMARK 500    TYR M   7   C   -  N   -  CA  ANGL. DEV. =  16.9 DEGREES          
REMARK 500    LEU q 140   CA  -  CB  -  CG  ANGL. DEV. =  19.6 DEGREES          
REMARK 500    ASP A 158   C   -  N   -  CA  ANGL. DEV. =  15.9 DEGREES          
REMARK 500    ASP B 320   CB  -  CG  -  OD1 ANGL. DEV. =   8.6 DEGREES          
REMARK 500    PRO D 336   C   -  N   -  CA  ANGL. DEV. =  10.4 DEGREES          
REMARK 500    PRO f 193   C   -  N   -  CA  ANGL. DEV. =  -9.7 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    LEU U  11       46.13    -78.74                                   
REMARK 500    PHE U  34       31.82    -93.09                                   
REMARK 500    GLU U 120       66.22     60.34                                   
REMARK 500    GLU U 131      -10.32     72.12                                   
REMARK 500    ASP U 161      -55.79   -120.42                                   
REMARK 500    GLU U 169     -164.52    -79.63                                   
REMARK 500    ASP U 224       60.63     37.64                                   
REMARK 500    ASP U 240       -2.80     76.53                                   
REMARK 500    ARG U 361     -157.18   -146.98                                   
REMARK 500    ASN U 398      -34.23     70.53                                   
REMARK 500    PRO U 428       42.78    -80.00                                   
REMARK 500    LYS U 429       11.56   -146.15                                   
REMARK 500    ASN U 452       -6.58     71.57                                   
REMARK 500    ASP U 471       28.69     43.27                                   
REMARK 500    MET U 560      -13.11     72.08                                   
REMARK 500    GLU U 561       -6.55   -147.62                                   
REMARK 500    ASN U 596      -12.23     70.33                                   
REMARK 500    GLU U 642        1.84    -64.00                                   
REMARK 500    ASN U 677       52.85    -92.09                                   
REMARK 500    GLN U 697       -4.28     69.52                                   
REMARK 500    GLN U 768       61.37   -108.12                                   
REMARK 500    LYS U 842     -150.83   -153.53                                   
REMARK 500    GLU U 843       61.58     66.49                                   
REMARK 500    SER U 907       -7.44   -143.80                                   
REMARK 500    THR V  43      -70.03    -62.68                                   
REMARK 500    ASP V  52      -72.07    -52.81                                   
REMARK 500    LYS V  54     -156.41   -154.36                                   
REMARK 500    THR V  55       65.60     60.95                                   
REMARK 500    HIS V  78      -73.44    -66.17                                   
REMARK 500    VAL V  79      -53.74   -137.91                                   
REMARK 500    LEU V  82      -64.95   -120.39                                   
REMARK 500    LYS V  84       13.31     58.65                                   
REMARK 500    ALA V  85     -159.50   -152.17                                   
REMARK 500    SER V  87       65.78     62.99                                   
REMARK 500    ARG V  96       62.22     38.01                                   
REMARK 500    LEU V  98      -27.33     73.12                                   
REMARK 500    ARG V  99       73.36     33.85                                   
REMARK 500    MET V 100     -156.64   -129.59                                   
REMARK 500    LEU V 101      145.40    -37.27                                   
REMARK 500    PRO V 102       12.63    -69.42                                   
REMARK 500    SER V 103       36.10    -95.86                                   
REMARK 500    ARG V 128       -5.94     72.68                                   
REMARK 500    ASP V 144      -70.96    -57.00                                   
REMARK 500    PRO V 161        8.83    -64.93                                   
REMARK 500    GLN V 168       14.08     59.40                                   
REMARK 500    GLN V 193       -2.98     75.27                                   
REMARK 500    LYS V 194      -16.15     64.93                                   
REMARK 500    ILE V 195      140.88   -176.99                                   
REMARK 500    ALA V 238       32.11    -96.44                                   
REMARK 500    ASP V 243       77.43   -108.36                                   
REMARK 500                                                                      
REMARK 500 THIS ENTRY HAS     552 RAMACHANDRAN OUTLIERS.                        
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS                                         
REMARK 500                                                                      
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH          
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED           
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND               
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.                                  
REMARK 500                                 MODEL     OMEGA                      
REMARK 500 SER U  432     PRO U  433                  149.03                    
REMARK 500 ALA U  598     ILE U  599                 -147.28                    
REMARK 500 LYS V  194     ILE V  195                  146.54                    
REMARK 500 GLU W  313     LEU W  314                 -146.05                    
REMARK 500 GLY Y  373     ASP Y  374                  149.37                    
REMARK 500 GLU Z  143     VAL Z  144                 -127.62                    
REMARK 500 VAL Z  158     THR Z  159                 -139.54                    
REMARK 500 GLU Z  166     ALA Z  167                 -132.94                    
REMARK 500 LYS Z  219     LEU Z  220                 -142.43                    
REMARK 500 HIS Z  224     GLN Z  225                  141.41                    
REMARK 500 GLN b  101     GLY b  102                  149.67                    
REMARK 500 ILE c   33     SER c   34                  149.75                    
REMARK 500 SER c  150     VAL c  151                 -144.07                    
REMARK 500 VAL c  155     VAL c  156                 -146.57                    
REMARK 500 ILE c  272     LYS c  273                 -121.68                    
REMARK 500 GLN c  278     ASP c  279                 -135.02                    
REMARK 500 ARG J    5     ALA J    6                  -73.43                    
REMARK 500 GLY K   19     ARG K   20                  -38.89                    
REMARK 500 PHE K   22     GLN K   23                  145.85                    
REMARK 500 LEU K  121     GLN K  122                  148.19                    
REMARK 500 GLY O  200     ARG O  201                 -140.04                    
REMARK 500 ALA j  180     ILE j  181                 -117.76                    
REMARK 500 GLY k   11     VAL k   12                 -149.14                    
REMARK 500 ILE A  157     ASP A  158                 -129.51                    
REMARK 500 THR A  233     ASP A  234                  149.50                    
REMARK 500 PRO A  311     ARG A  312                 -142.15                    
REMARK 500 ALA B  278     PRO B  279                  147.37                    
REMARK 500 LYS C   88     VAL C   89                 -146.34                    
REMARK 500 VAL C   89     HIS C   90                 -145.18                    
REMARK 500 HIS C   90     PRO C   91                  149.19                    
REMARK 500 ASN C  129     LYS C  130                  146.36                    
REMARK 500 ASP C  132     PRO C  133                  124.49                    
REMARK 500 MET C  230     VAL C  231                 -125.02                    
REMARK 500 ASN C  288     ILE C  289                 -103.93                    
REMARK 500 GLU C  358     VAL C  359                  149.22                    
REMARK 500 LYS C  397     ASN C  398                 -137.23                    
REMARK 500 SER C  400     ILE C  401                   67.67                    
REMARK 500 SER D   84     ILE D   85                  124.35                    
REMARK 500 ASP D  318     PRO D  319                  132.69                    
REMARK 500 LEU D  354     SER D  355                 -146.01                    
REMARK 500 SER D  355     GLU D  356                  128.75                    
REMARK 500 ILE D  370     SER D  371                 -137.46                    
REMARK 500 SER D  371     GLY D  372                 -145.04                    
REMARK 500 GLU D  413     HIS D  414                   65.66                    
REMARK 500 TYR D  417     LYS D  418                 -148.61                    
REMARK 500 LEU F   86     PRO F   87                  149.25                    
REMARK 500 PRO F   87     TYR F   88                 -143.28                    
REMARK 500 LEU F  343     ARG F  344                 -131.66                    
REMARK 500 LEU F  425     GLU F  426                  147.58                    
REMARK 500 GLU F  426     VAL F  427                 -141.65                    
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: MAIN CHAIN PLANARITY                                       
REMARK 500                                                                      
REMARK 500 THE FOLLOWING RESIDUES HAVE A PSEUDO PLANARITY                       
REMARK 500 TORSION ANGLE, C(I) - CA(I) - N(I+1) - O(I), GREATER                 
REMARK 500 10.0 DEGREES. (M=MODEL NUMBER; RES=RESIDUE NAME;                     
REMARK 500 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;                            
REMARK 500 I=INSERTION CODE).                                                   
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        ANGLE                                           
REMARK 500    ASP J 184        -10.03                                           
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN c 401  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 SER c 114   N                                                      
REMARK 620 2 SER c 114   O    78.7                                              
REMARK 620 N                    1                                               
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue ZN c 401                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue AGS A 501                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue AGS B 501                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue AGS D 501                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: binding site for residue AGS F 501                 
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: EMD-8665   RELATED DB: EMDB                              
REMARK 900 NUCLEOTIDE-DRIVEN TRIPLE-STATE REMODELING OF THE AAA-ATPASE CHANNEL  
REMARK 900 IN THE ACTIVATED HUMAN 26S PROTEASOME                                
REMARK 900 RELATED ID: EMD-8662   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8663   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8664   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8666   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8667   RELATED DB: EMDB                              
REMARK 900 RELATED ID: EMD-8668   RELATED DB: EMDB                              
REMARK 900 RELATED ID: 5VFS   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFO   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFP   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFQ   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFT   RELATED DB: PDB                                   
REMARK 900 RELATED ID: 5VFU   RELATED DB: PDB                                   
DBREF  5VFR U    7   917  UNP    Q99460   PSMD1_HUMAN      7    917             
DBREF  5VFR V   18   497  UNP    O43242   PSMD3_HUMAN     18    497             
DBREF  5VFR W    1   456  UNP    O00232   PSD12_HUMAN      1    456             
DBREF  5VFR X   43   422  UNP    O00231   PSD11_HUMAN     43    422             
DBREF  5VFR Y   12   389  UNP    Q15008   PSMD6_HUMAN     12    389             
DBREF  5VFR Z    5   290  UNP    P51665   PSMD7_HUMAN      5    290             
DBREF  5VFR a    4   376  UNP    Q9UNM6   PSD13_HUMAN      4    376             
DBREF  5VFR b    1   191  UNP    P55036   PSMD4_HUMAN      1    191             
DBREF  5VFR c   24   310  UNP    O00487   PSDE_HUMAN      24    310             
DBREF  5VFR d    1   257  UNP    P48556   PSMD8_HUMAN     94    350             
DBREF  5VFR e    1    70  PDB    5VFR     5VFR             1     70             
DBREF  5VFR G    5   244  UNP    P60900   PSA6_HUMAN       5    244             
DBREF  5VFR H    3   234  UNP    P25787   PSA2_HUMAN       3    234             
DBREF  5VFR I    2   251  UNP    P25789   PSA4_HUMAN       2    251             
DBREF  5VFR J    2   244  UNP    O14818   PSA7_HUMAN       2    244             
DBREF  5VFR K    8   241  UNP    P28066   PSA5_HUMAN       8    241             
DBREF  5VFR L    4   241  UNP    P25786   PSA1_HUMAN       4    241             
DBREF  5VFR M    1   245  UNP    P25788   PSA3_HUMAN       2    246             
DBREF  5VFR N    1   191  UNP    P28072   PSB6_HUMAN      35    225             
DBREF  5VFR O    1   220  UNP    Q99436   PSB7_HUMAN      44    263             
DBREF  5VFR P    2   205  UNP    P49720   PSB3_HUMAN       2    205             
DBREF  5VFR Q    1   199  UNP    P49721   PSB2_HUMAN       1    199             
DBREF  5VFR R    1   201  UNP    P28074   PSB5_HUMAN      60    260             
DBREF  5VFR S    1   213  UNP    P20618   PSB1_HUMAN      29    241             
DBREF  5VFR T    1   215  UNP    P28070   PSB4_HUMAN      46    260             
DBREF  5VFR g    5   244  UNP    P60900   PSA6_HUMAN       5    244             
DBREF  5VFR h    3   234  UNP    P25787   PSA2_HUMAN       3    234             
DBREF  5VFR i    2   251  UNP    P25789   PSA4_HUMAN       2    251             
DBREF  5VFR j    2   244  UNP    O14818   PSA7_HUMAN       2    244             
DBREF  5VFR k    8   241  UNP    P28066   PSA5_HUMAN       8    241             
DBREF  5VFR l    4   241  UNP    P25786   PSA1_HUMAN       4    241             
DBREF  5VFR m    1   245  UNP    P25788   PSA3_HUMAN       2    246             
DBREF  5VFR n    1   191  UNP    P28072   PSB6_HUMAN      35    225             
DBREF  5VFR o    1   220  UNP    Q99436   PSB7_HUMAN      44    263             
DBREF  5VFR p    2   205  UNP    P49720   PSB3_HUMAN       2    205             
DBREF  5VFR q    1   199  UNP    P49721   PSB2_HUMAN       1    199             
DBREF  5VFR r    1   201  UNP    P28074   PSB5_HUMAN      60    260             
DBREF  5VFR s    1   213  UNP    P20618   PSB1_HUMAN      29    241             
DBREF  5VFR t    1   215  UNP    P28070   PSB4_HUMAN      46    260             
DBREF  5VFR A   35   433  UNP    P35998   PRS7_HUMAN      35    433             
DBREF  5VFR B   52   440  UNP    P62191   PRS4_HUMAN      52    440             
DBREF  5VFR C   11   402  UNP    P62195   PRS8_HUMAN       3    394             
DBREF  5VFR D   39   418  UNP    P43686   PRS6B_HUMAN     39    418             
DBREF  5VFR E   15   389  UNP    P62333   PRS10_HUMAN     15    389             
DBREF  5VFR F   44   439  UNP    P17980   PRS6A_HUMAN     44    439             
DBREF  5VFR f    1   694  UNP    Q13200   PSMD2_HUMAN      1    694             
SEQRES   1 U  911  GLY ILE ILE SER LEU LEU ASP GLU ASP GLU PRO GLN LEU          
SEQRES   2 U  911  LYS GLU PHE ALA LEU HIS LYS LEU ASN ALA VAL VAL ASN          
SEQRES   3 U  911  ASP PHE TRP ALA GLU ILE SER GLU SER VAL ASP LYS ILE          
SEQRES   4 U  911  GLU VAL LEU TYR GLU ASP GLU GLY PHE ARG SER ARG GLN          
SEQRES   5 U  911  PHE ALA ALA LEU VAL ALA SER LYS VAL PHE TYR HIS LEU          
SEQRES   6 U  911  GLY ALA PHE GLU GLU SER LEU ASN TYR ALA LEU GLY ALA          
SEQRES   7 U  911  GLY ASP LEU PHE ASN VAL ASN ASP ASN SER GLU TYR VAL          
SEQRES   8 U  911  GLU THR ILE ILE ALA LYS CYS ILE ASP HIS TYR THR LYS          
SEQRES   9 U  911  GLN CYS VAL GLU ASN ALA ASP LEU PRO GLU GLY GLU LYS          
SEQRES  10 U  911  LYS PRO ILE ASP GLN ARG LEU GLU GLY ILE VAL ASN LYS          
SEQRES  11 U  911  MET PHE GLN ARG CYS LEU ASP ASP HIS LYS TYR LYS GLN          
SEQRES  12 U  911  ALA ILE GLY ILE ALA LEU GLU THR ARG ARG LEU ASP VAL          
SEQRES  13 U  911  PHE GLU LYS THR ILE LEU GLU SER ASN ASP VAL PRO GLY          
SEQRES  14 U  911  MET LEU ALA TYR SER LEU LYS LEU CYS MET SER LEU MET          
SEQRES  15 U  911  GLN ASN LYS GLN PHE ARG ASN LYS VAL LEU ARG VAL LEU          
SEQRES  16 U  911  VAL LYS ILE TYR MET ASN LEU GLU LYS PRO ASP PHE ILE          
SEQRES  17 U  911  ASN VAL CYS GLN CYS LEU ILE PHE LEU ASP ASP PRO GLN          
SEQRES  18 U  911  ALA VAL SER ASP ILE LEU GLU LYS LEU VAL LYS GLU ASP          
SEQRES  19 U  911  ASN LEU LEU MET ALA TYR GLN ILE CYS PHE ASP LEU TYR          
SEQRES  20 U  911  GLU SER ALA SER GLN GLN PHE LEU SER SER VAL ILE GLN          
SEQRES  21 U  911  ASN LEU ARG THR VAL GLY THR PRO ILE ALA SER VAL PRO          
SEQRES  22 U  911  GLY SER THR ASN THR GLY THR VAL PRO GLY SER GLU LYS          
SEQRES  23 U  911  ASP SER ASP SER MET GLU THR GLU GLU LYS THR SER SER          
SEQRES  24 U  911  ALA PHE VAL GLY LYS THR PRO GLU ALA SER PRO GLU PRO          
SEQRES  25 U  911  LYS ASP GLN THR LEU LYS MET ILE LYS ILE LEU SER GLY          
SEQRES  26 U  911  GLU MET ALA ILE GLU LEU HIS LEU GLN PHE LEU ILE ARG          
SEQRES  27 U  911  ASN ASN ASN THR ASP LEU MET ILE LEU LYS ASN THR LYS          
SEQRES  28 U  911  ASP ALA VAL ARG ASN SER VAL CYS HIS THR ALA THR VAL          
SEQRES  29 U  911  ILE ALA ASN SER PHE MET HIS CYS GLY THR THR SER ASP          
SEQRES  30 U  911  GLN PHE LEU ARG ASP ASN LEU GLU TRP LEU ALA ARG ALA          
SEQRES  31 U  911  THR ASN TRP ALA LYS PHE THR ALA THR ALA SER LEU GLY          
SEQRES  32 U  911  VAL ILE HIS LYS GLY HIS GLU LYS GLU ALA LEU GLN LEU          
SEQRES  33 U  911  MET ALA THR TYR LEU PRO LYS ASP THR SER PRO GLY SER          
SEQRES  34 U  911  ALA TYR GLN GLU GLY GLY GLY LEU TYR ALA LEU GLY LEU          
SEQRES  35 U  911  ILE HIS ALA ASN HIS GLY GLY ASP ILE ILE ASP TYR LEU          
SEQRES  36 U  911  LEU ASN GLN LEU LYS ASN ALA SER ASN ASP ILE VAL ARG          
SEQRES  37 U  911  HIS GLY GLY SER LEU GLY LEU GLY LEU ALA ALA MET GLY          
SEQRES  38 U  911  THR ALA ARG GLN ASP VAL TYR ASP LEU LEU LYS THR ASN          
SEQRES  39 U  911  LEU TYR GLN ASP ASP ALA VAL THR GLY GLU ALA ALA GLY          
SEQRES  40 U  911  LEU ALA LEU GLY LEU VAL MET LEU GLY SER LYS ASN ALA          
SEQRES  41 U  911  GLN ALA ILE GLU ASP MET VAL GLY TYR ALA GLN GLU THR          
SEQRES  42 U  911  GLN HIS GLU LYS ILE LEU ARG GLY LEU ALA VAL GLY ILE          
SEQRES  43 U  911  ALA LEU VAL MET TYR GLY ARG MET GLU GLU ALA ASP ALA          
SEQRES  44 U  911  LEU ILE GLU SER LEU CYS ARG ASP LYS ASP PRO ILE LEU          
SEQRES  45 U  911  ARG ARG SER GLY MET TYR THR VAL ALA MET ALA TYR CYS          
SEQRES  46 U  911  GLY SER GLY ASN ASN LYS ALA ILE ARG ARG LEU LEU HIS          
SEQRES  47 U  911  VAL ALA VAL SER ASP VAL ASN ASP ASP VAL ARG ARG ALA          
SEQRES  48 U  911  ALA VAL GLU SER LEU GLY PHE ILE LEU PHE ARG THR PRO          
SEQRES  49 U  911  GLU GLN CYS PRO SER VAL VAL SER LEU LEU SER GLU SER          
SEQRES  50 U  911  TYR ASN PRO HIS VAL ARG TYR GLY ALA ALA MET ALA LEU          
SEQRES  51 U  911  GLY ILE CYS CYS ALA GLY THR GLY ASN LYS GLU ALA ILE          
SEQRES  52 U  911  ASN LEU LEU GLU PRO MET THR ASN ASP PRO VAL ASN TYR          
SEQRES  53 U  911  VAL ARG GLN GLY ALA LEU ILE ALA SER ALA LEU ILE MET          
SEQRES  54 U  911  ILE GLN GLN THR GLU ILE THR CYS PRO LYS VAL ASN GLN          
SEQRES  55 U  911  PHE ARG GLN LEU TYR SER LYS VAL ILE ASN ASP LYS HIS          
SEQRES  56 U  911  ASP ASP VAL MET ALA LYS PHE GLY ALA ILE LEU ALA GLN          
SEQRES  57 U  911  GLY ILE LEU ASP ALA GLY GLY HIS ASN VAL THR ILE SER          
SEQRES  58 U  911  LEU GLN SER ARG THR GLY HIS THR HIS MET PRO SER VAL          
SEQRES  59 U  911  VAL GLY VAL LEU VAL PHE THR GLN PHE TRP PHE TRP PHE          
SEQRES  60 U  911  PRO LEU SER HIS PHE LEU SER LEU ALA TYR THR PRO THR          
SEQRES  61 U  911  CYS VAL ILE GLY LEU ASN LYS ASP LEU LYS MET PRO LYS          
SEQRES  62 U  911  VAL GLN TYR LYS SER ASN CYS LYS PRO SER THR PHE ALA          
SEQRES  63 U  911  TYR PRO ALA PRO LEU GLU VAL PRO LYS GLU LYS GLU LYS          
SEQRES  64 U  911  GLU LYS VAL SER THR ALA VAL LEU SER ILE THR ALA LYS          
SEQRES  65 U  911  ALA LYS LYS LYS GLU LYS GLU LYS GLU LYS LYS GLU GLU          
SEQRES  66 U  911  GLU LYS MET GLU VAL ASP GLU ALA GLU LYS LYS GLU GLU          
SEQRES  67 U  911  LYS GLU LYS LYS LYS GLU PRO GLU PRO ASN PHE GLN LEU          
SEQRES  68 U  911  LEU ASP ASN PRO ALA ARG VAL MET PRO ALA GLN LEU LYS          
SEQRES  69 U  911  VAL LEU THR MET PRO GLU THR CYS ARG TYR GLN PRO PHE          
SEQRES  70 U  911  LYS PRO LEU SER ILE GLY GLY ILE ILE ILE LEU LYS ASP          
SEQRES  71 U  911  THR                                                          
SEQRES   1 V  480  PRO PRO GLY GLY GLY GLU GLN GLU PRO PRO PRO PRO PRO          
SEQRES   2 V  480  ALA PRO GLN ASP VAL GLU MET LYS GLU GLU ALA ALA THR          
SEQRES   3 V  480  GLY GLY GLY SER THR GLY GLU ALA ASP GLY LYS THR ALA          
SEQRES   4 V  480  ALA ALA ALA ALA GLU HIS SER GLN ARG GLU LEU ASP THR          
SEQRES   5 V  480  VAL THR LEU GLU ASP ILE LYS GLU HIS VAL LYS GLN LEU          
SEQRES   6 V  480  GLU LYS ALA VAL SER GLY LYS GLU PRO ARG PHE VAL LEU          
SEQRES   7 V  480  ARG ALA LEU ARG MET LEU PRO SER THR SER ARG ARG LEU          
SEQRES   8 V  480  ASN HIS TYR VAL LEU TYR LYS ALA VAL GLN GLY PHE PHE          
SEQRES   9 V  480  THR SER ASN ASN ALA THR ARG ASP PHE LEU LEU PRO PHE          
SEQRES  10 V  480  LEU GLU GLU PRO MET ASP THR GLU ALA ASP LEU GLN PHE          
SEQRES  11 V  480  ARG PRO ARG THR GLY LYS ALA ALA SER THR PRO LEU LEU          
SEQRES  12 V  480  PRO GLU VAL GLU ALA TYR LEU GLN LEU LEU VAL VAL ILE          
SEQRES  13 V  480  PHE MET MET ASN SER LYS ARG TYR LYS GLU ALA GLN LYS          
SEQRES  14 V  480  ILE SER ASP ASP LEU MET GLN LYS ILE SER THR GLN ASN          
SEQRES  15 V  480  ARG ARG ALA LEU ASP LEU VAL ALA ALA LYS CYS TYR TYR          
SEQRES  16 V  480  TYR HIS ALA ARG VAL TYR GLU PHE LEU ASP LYS LEU ASP          
SEQRES  17 V  480  VAL VAL ARG SER PHE LEU HIS ALA ARG LEU ARG THR ALA          
SEQRES  18 V  480  THR LEU ARG HIS ASP ALA ASP GLY GLN ALA THR LEU LEU          
SEQRES  19 V  480  ASN LEU LEU LEU ARG ASN TYR LEU HIS TYR SER LEU TYR          
SEQRES  20 V  480  ASP GLN ALA GLU LYS LEU VAL SER LYS SER VAL PHE PRO          
SEQRES  21 V  480  GLU GLN ALA ASN ASN ASN GLU TRP ALA ARG TYR LEU TYR          
SEQRES  22 V  480  TYR THR GLY ARG ILE LYS ALA ILE GLN LEU GLU TYR SER          
SEQRES  23 V  480  GLU ALA ARG ARG THR MET THR ASN ALA LEU ARG LYS ALA          
SEQRES  24 V  480  PRO GLN HIS THR ALA VAL GLY PHE LYS GLN THR VAL HIS          
SEQRES  25 V  480  LYS LEU LEU ILE VAL VAL GLU LEU LEU LEU GLY GLU ILE          
SEQRES  26 V  480  PRO ASP ARG LEU GLN PHE ARG GLN PRO SER LEU LYS ARG          
SEQRES  27 V  480  SER LEU MET PRO TYR PHE LEU LEU THR GLN ALA VAL ARG          
SEQRES  28 V  480  THR GLY ASN LEU ALA LYS PHE ASN GLN VAL LEU ASP GLN          
SEQRES  29 V  480  PHE GLY GLU LYS PHE GLN ALA ASP GLY THR TYR THR LEU          
SEQRES  30 V  480  ILE ILE ARG LEU ARG HIS ASN VAL ILE LYS THR GLY VAL          
SEQRES  31 V  480  ARG MET ILE SER LEU SER TYR SER ARG ILE SER LEU ALA          
SEQRES  32 V  480  ASP ILE ALA GLN LYS LEU GLN LEU ASP SER PRO GLU ASP          
SEQRES  33 V  480  ALA GLU PHE ILE VAL ALA LYS ALA ILE ARG ASP GLY VAL          
SEQRES  34 V  480  ILE GLU ALA SER ILE ASN HIS GLU LYS GLY TYR VAL GLN          
SEQRES  35 V  480  SER LYS GLU MET ILE ASP ILE TYR SER THR ARG GLU PRO          
SEQRES  36 V  480  GLN LEU ALA PHE HIS GLN ARG ILE SER PHE CYS LEU ASP          
SEQRES  37 V  480  ILE HIS ASN MET SER VAL LYS ALA MET ARG PHE PRO              
SEQRES   1 W  456  MET ALA ASP GLY GLY SER GLU ARG ALA ASP GLY ARG ILE          
SEQRES   2 W  456  VAL LYS MET GLU VAL ASP TYR SER ALA THR VAL ASP GLN          
SEQRES   3 W  456  ARG LEU PRO GLU CYS ALA LYS LEU ALA LYS GLU GLY ARG          
SEQRES   4 W  456  LEU GLN GLU VAL ILE GLU THR LEU LEU SER LEU GLU LYS          
SEQRES   5 W  456  GLN THR ARG THR ALA SER ASP MET VAL SER THR SER ARG          
SEQRES   6 W  456  ILE LEU VAL ALA VAL VAL LYS MET CYS TYR GLU ALA LYS          
SEQRES   7 W  456  GLU TRP ASP LEU LEU ASN GLU ASN ILE MET LEU LEU SER          
SEQRES   8 W  456  LYS ARG ARG SER GLN LEU LYS GLN ALA VAL ALA LYS MET          
SEQRES   9 W  456  VAL GLN GLN CYS CYS THR TYR VAL GLU GLU ILE THR ASP          
SEQRES  10 W  456  LEU PRO ILE LYS LEU ARG LEU ILE ASP THR LEU ARG MET          
SEQRES  11 W  456  VAL THR GLU GLY LYS ILE TYR VAL GLU ILE GLU ARG ALA          
SEQRES  12 W  456  ARG LEU THR LYS THR LEU ALA THR ILE LYS GLU GLN ASN          
SEQRES  13 W  456  GLY ASP VAL LYS GLU ALA ALA SER ILE LEU GLN GLU LEU          
SEQRES  14 W  456  GLN VAL GLU THR TYR GLY SER MET GLU LYS LYS GLU ARG          
SEQRES  15 W  456  VAL GLU PHE ILE LEU GLU GLN MET ARG LEU CYS LEU ALA          
SEQRES  16 W  456  VAL LYS ASP TYR ILE ARG THR GLN ILE ILE SER LYS LYS          
SEQRES  17 W  456  ILE ASN THR LYS PHE PHE GLN GLU GLU ASN THR GLU LYS          
SEQRES  18 W  456  LEU LYS LEU LYS TYR TYR ASN LEU MET ILE GLN LEU ASP          
SEQRES  19 W  456  GLN HIS GLU GLY SER TYR LEU SER ILE CYS LYS HIS TYR          
SEQRES  20 W  456  ARG ALA ILE TYR ASP THR PRO CYS ILE GLN ALA GLU SER          
SEQRES  21 W  456  GLU LYS TRP GLN GLN ALA LEU LYS SER VAL VAL LEU TYR          
SEQRES  22 W  456  VAL ILE LEU ALA PRO PHE ASP ASN GLU GLN SER ASP LEU          
SEQRES  23 W  456  VAL HIS ARG ILE SER GLY ASP LYS LYS LEU GLU GLU ILE          
SEQRES  24 W  456  PRO LYS TYR LYS ASP LEU LEU LYS LEU PHE THR THR MET          
SEQRES  25 W  456  GLU LEU MET ARG TRP SER THR LEU VAL GLU ASP TYR GLY          
SEQRES  26 W  456  MET GLU LEU ARG LYS GLY SER LEU GLU SER PRO ALA THR          
SEQRES  27 W  456  ASP VAL PHE GLY SER THR GLU GLU GLY GLU LYS ARG TRP          
SEQRES  28 W  456  LYS ASP LEU LYS ASN ARG VAL VAL GLU HIS ASN ILE ARG          
SEQRES  29 W  456  ILE MET ALA LYS TYR TYR THR ARG ILE THR MET LYS ARG          
SEQRES  30 W  456  MET ALA GLN LEU LEU ASP LEU SER VAL ASP GLU SER GLU          
SEQRES  31 W  456  ALA PHE LEU SER ASN LEU VAL VAL ASN LYS THR ILE PHE          
SEQRES  32 W  456  ALA LYS VAL ASP ARG LEU ALA GLY ILE ILE ASN PHE GLN          
SEQRES  33 W  456  ARG PRO LYS ASP PRO ASN ASN LEU LEU ASN ASP TRP SER          
SEQRES  34 W  456  GLN LYS LEU ASN SER LEU MET SER LEU VAL ASN LYS THR          
SEQRES  35 W  456  THR HIS LEU ILE ALA LYS GLU GLU MET ILE HIS ASN LEU          
SEQRES  36 W  456  GLN                                                          
SEQRES   1 X  380  VAL GLN VAL LYS GLU GLN SER ILE LEU GLU LEU GLY SER          
SEQRES   2 X  380  LEU LEU ALA LYS THR GLY GLN ALA ALA GLU LEU GLY GLY          
SEQRES   3 X  380  LEU LEU LYS TYR VAL ARG PRO PHE LEU ASN SER ILE SER          
SEQRES   4 X  380  LYS ALA LYS ALA ALA ARG LEU VAL ARG SER LEU LEU ASP          
SEQRES   5 X  380  LEU PHE LEU ASP MET GLU ALA ALA THR GLY GLN GLU VAL          
SEQRES   6 X  380  GLU LEU CYS LEU GLU CYS ILE GLU TRP ALA LYS SER GLU          
SEQRES   7 X  380  LYS ARG THR PHE LEU ARG GLN ALA LEU GLU ALA ARG LEU          
SEQRES   8 X  380  VAL SER LEU TYR PHE ASP THR LYS ARG TYR GLN GLU ALA          
SEQRES   9 X  380  LEU HIS LEU GLY SER GLN LEU LEU ARG GLU LEU LYS LYS          
SEQRES  10 X  380  MET ASP ASP LYS ALA LEU LEU VAL GLU VAL GLN LEU LEU          
SEQRES  11 X  380  GLU SER LYS THR TYR HIS ALA LEU SER ASN LEU PRO LYS          
SEQRES  12 X  380  ALA ARG ALA ALA LEU THR SER ALA ARG THR THR ALA ASN          
SEQRES  13 X  380  ALA ILE TYR CYS PRO PRO LYS LEU GLN ALA THR LEU ASP          
SEQRES  14 X  380  MET GLN SER GLY ILE ILE HIS ALA ALA GLU GLU LYS ASP          
SEQRES  15 X  380  TRP LYS THR ALA TYR SER TYR PHE TYR GLU ALA PHE GLU          
SEQRES  16 X  380  GLY TYR ASP SER ILE ASP SER PRO LYS ALA ILE THR SER          
SEQRES  17 X  380  LEU LYS TYR MET LEU LEU CYS LYS ILE MET LEU ASN THR          
SEQRES  18 X  380  PRO GLU ASP VAL GLN ALA LEU VAL SER GLY LYS LEU ALA          
SEQRES  19 X  380  LEU ARG TYR ALA GLY ARG GLN THR GLU ALA LEU LYS CYS          
SEQRES  20 X  380  VAL ALA GLN ALA SER LYS ASN ARG SER LEU ALA ASP PHE          
SEQRES  21 X  380  GLU LYS ALA LEU THR ASP TYR ARG ALA GLU LEU ARG ASP          
SEQRES  22 X  380  ASP PRO ILE ILE SER THR HIS LEU ALA LYS LEU TYR ASP          
SEQRES  23 X  380  ASN LEU LEU GLU GLN ASN LEU ILE ARG VAL ILE GLU PRO          
SEQRES  24 X  380  PHE SER ARG VAL GLN ILE GLU HIS ILE SER SER LEU ILE          
SEQRES  25 X  380  LYS LEU SER LYS ALA ASP VAL GLU ARG LYS LEU SER GLN          
SEQRES  26 X  380  MET ILE LEU ASP LYS LYS PHE HIS GLY ILE LEU ASP GLN          
SEQRES  27 X  380  GLY GLU GLY VAL LEU ILE ILE PHE ASP GLU PRO PRO VAL          
SEQRES  28 X  380  ASP LYS THR TYR GLU ALA ALA LEU GLU THR ILE GLN ASN          
SEQRES  29 X  380  MET SER LYS VAL VAL ASP SER LEU TYR ASN LYS ALA LYS          
SEQRES  30 X  380  LYS LEU THR                                                  
SEQRES   1 Y  378  PRO LYS ASN PRO ASP LEU ARG ILE ALA GLN LEU ARG PHE          
SEQRES   2 Y  378  LEU LEU SER LEU PRO GLU HIS ARG GLY ASP ALA ALA VAL          
SEQRES   3 Y  378  ARG ASP GLU LEU MET ALA ALA VAL ARG ASP ASN ASN MET          
SEQRES   4 Y  378  ALA PRO TYR TYR GLU ALA LEU CYS LYS SER LEU ASP TRP          
SEQRES   5 Y  378  GLN ILE ASP VAL ASP LEU LEU ASN LYS MET LYS LYS ALA          
SEQRES   6 Y  378  ASN GLU ASP GLU LEU LYS ARG LEU ASP GLU GLU LEU GLU          
SEQRES   7 Y  378  ASP ALA GLU LYS ASN LEU GLY GLU SER GLU ILE ARG ASP          
SEQRES   8 Y  378  ALA MET MET ALA LYS ALA GLU TYR LEU CYS ARG ILE GLY          
SEQRES   9 Y  378  ASP LYS GLU GLY ALA LEU THR ALA PHE ARG LYS THR TYR          
SEQRES  10 Y  378  ASP LYS THR VAL ALA LEU GLY HIS ARG LEU ASP ILE VAL          
SEQRES  11 Y  378  PHE TYR LEU LEU ARG ILE GLY LEU PHE TYR MET ASP ASN          
SEQRES  12 Y  378  ASP LEU ILE THR ARG ASN THR GLU LYS ALA LYS SER LEU          
SEQRES  13 Y  378  ILE GLU GLU GLY GLY ASP TRP ASP ARG ARG ASN ARG LEU          
SEQRES  14 Y  378  LYS VAL TYR GLN GLY LEU TYR CYS VAL ALA ILE ARG ASP          
SEQRES  15 Y  378  PHE LYS GLN ALA ALA GLU LEU PHE LEU ASP THR VAL SER          
SEQRES  16 Y  378  THR PHE THR SER TYR GLU LEU MET ASP TYR LYS THR PHE          
SEQRES  17 Y  378  VAL THR TYR THR VAL TYR VAL SER MET ILE ALA LEU GLU          
SEQRES  18 Y  378  ARG PRO ASP LEU ARG GLU LYS VAL ILE LYS GLY ALA GLU          
SEQRES  19 Y  378  ILE LEU GLU VAL LEU HIS SER LEU PRO ALA VAL ARG GLN          
SEQRES  20 Y  378  TYR LEU PHE SER LEU TYR GLU CYS ARG TYR SER VAL PHE          
SEQRES  21 Y  378  PHE GLN SER LEU ALA VAL VAL GLU GLN GLU MET LYS LYS          
SEQRES  22 Y  378  ASP TRP LEU PHE ALA PRO HIS TYR ARG TYR TYR VAL ARG          
SEQRES  23 Y  378  GLU MET ARG ILE HIS ALA TYR SER GLN LEU LEU GLU SER          
SEQRES  24 Y  378  TYR ARG SER LEU THR LEU GLY TYR MET ALA GLU ALA PHE          
SEQRES  25 Y  378  GLY VAL GLY VAL GLU PHE ILE ASP GLN GLU LEU SER ARG          
SEQRES  26 Y  378  PHE ILE ALA ALA GLY ARG LEU HIS CYS LYS ILE ASP LYS          
SEQRES  27 Y  378  VAL ASN GLU ILE VAL GLU THR ASN ARG PRO ASP SER LYS          
SEQRES  28 Y  378  ASN TRP GLN TYR GLN GLU THR ILE LYS LYS GLY ASP LEU          
SEQRES  29 Y  378  LEU LEU ASN ARG VAL GLN LYS LEU SER ARG VAL ILE ASN          
SEQRES  30 Y  378  MET                                                          
SEQRES   1 Z  286  ALA VAL GLN LYS VAL VAL VAL HIS PRO LEU VAL LEU LEU          
SEQRES   2 Z  286  SER VAL VAL ASP HIS PHE ASN ARG ILE GLY LYS VAL GLY          
SEQRES   3 Z  286  ASN GLN LYS ARG VAL VAL GLY VAL LEU LEU GLY SER TRP          
SEQRES   4 Z  286  GLN LYS LYS VAL LEU ASP VAL SER ASN SER PHE ALA VAL          
SEQRES   5 Z  286  PRO PHE ASP GLU ASP ASP LYS ASP ASP SER VAL TRP PHE          
SEQRES   6 Z  286  LEU ASP HIS ASP TYR LEU GLU ASN MET TYR GLY MET PHE          
SEQRES   7 Z  286  LYS LYS VAL ASN ALA ARG GLU ARG ILE VAL GLY TRP TYR          
SEQRES   8 Z  286  HIS THR GLY PRO LYS LEU HIS LYS ASN ASP ILE ALA ILE          
SEQRES   9 Z  286  ASN GLU LEU MET LYS ARG TYR CYS PRO ASN SER VAL LEU          
SEQRES  10 Z  286  VAL ILE ILE ASP VAL LYS PRO LYS ASP LEU GLY LEU PRO          
SEQRES  11 Z  286  THR GLU ALA TYR ILE SER VAL GLU GLU VAL HIS ASP ASP          
SEQRES  12 Z  286  GLY THR PRO THR SER LYS THR PHE GLU HIS VAL THR SER          
SEQRES  13 Z  286  GLU ILE GLY ALA GLU GLU ALA GLU GLU VAL GLY VAL GLU          
SEQRES  14 Z  286  HIS LEU LEU ARG ASP ILE LYS ASP THR THR VAL GLY THR          
SEQRES  15 Z  286  LEU SER GLN ARG ILE THR ASN GLN VAL HIS GLY LEU LYS          
SEQRES  16 Z  286  GLY LEU ASN SER LYS LEU LEU ASP ILE ARG SER TYR LEU          
SEQRES  17 Z  286  GLU LYS VAL ALA THR GLY LYS LEU PRO ILE ASN HIS GLN          
SEQRES  18 Z  286  ILE ILE TYR GLN LEU GLN ASP VAL PHE ASN LEU LEU PRO          
SEQRES  19 Z  286  ASP VAL SER LEU GLN GLU PHE VAL LYS ALA PHE TYR LEU          
SEQRES  20 Z  286  LYS THR ASN ASP GLN MET VAL VAL VAL TYR LEU ALA SER          
SEQRES  21 Z  286  LEU ILE ARG SER VAL VAL ALA LEU HIS ASN LEU ILE ASN          
SEQRES  22 Z  286  ASN LYS ILE ALA ASN ARG ASP ALA GLU LYS LYS GLU GLY          
SEQRES   1 a  373  VAL PRO GLY PHE LEU GLN GLN SER GLN ASN SER GLY PRO          
SEQRES   2 a  373  GLY GLN PRO ALA VAL TRP HIS ARG LEU GLU GLU LEU TYR          
SEQRES   3 a  373  THR LYS LYS LEU TRP HIS GLN LEU THR LEU GLN VAL LEU          
SEQRES   4 a  373  ASP PHE VAL GLN ASP PRO CYS PHE ALA GLN GLY ASP GLY          
SEQRES   5 a  373  LEU ILE LYS LEU TYR GLU ASN PHE ILE SER GLU PHE GLU          
SEQRES   6 a  373  HIS ARG VAL ASN PRO LEU SER LEU VAL GLU ILE ILE LEU          
SEQRES   7 a  373  HIS VAL VAL ARG GLN MET THR ASP PRO ASN VAL ALA LEU          
SEQRES   8 a  373  THR PHE LEU GLU LYS THR ARG GLU LYS VAL LYS SER SER          
SEQRES   9 a  373  ASP GLU ALA VAL ILE LEU CYS LYS THR ALA ILE GLY ALA          
SEQRES  10 a  373  LEU LYS LEU ASN ILE GLY ASP LEU GLN VAL THR LYS GLU          
SEQRES  11 a  373  THR ILE GLU ASP VAL GLU GLU MET LEU ASN ASN LEU PRO          
SEQRES  12 a  373  GLY VAL THR SER VAL HIS SER ARG PHE TYR ASP LEU SER          
SEQRES  13 a  373  SER LYS TYR TYR GLN THR ILE GLY ASN HIS ALA SER TYR          
SEQRES  14 a  373  TYR LYS ASP ALA LEU ARG PHE LEU GLY CYS VAL ASP ILE          
SEQRES  15 a  373  LYS ASP LEU PRO VAL SER GLU GLN GLN GLU ARG ALA PHE          
SEQRES  16 a  373  THR LEU GLY LEU ALA GLY LEU LEU GLY GLU GLY VAL PHE          
SEQRES  17 a  373  ASN PHE GLY GLU LEU LEU MET HIS PRO VAL LEU GLU SER          
SEQRES  18 a  373  LEU ARG ASN THR ASP ARG GLN TRP LEU ILE ASP THR LEU          
SEQRES  19 a  373  TYR ALA PHE ASN SER GLY ASN VAL GLU ARG PHE GLN THR          
SEQRES  20 a  373  LEU LYS THR ALA TRP GLY GLN GLN PRO ASP LEU ALA ALA          
SEQRES  21 a  373  ASN GLU ALA GLN LEU LEU ARG LYS ILE GLN LEU LEU CYS          
SEQRES  22 a  373  LEU MET GLU MET THR PHE THR ARG PRO ALA ASN HIS ARG          
SEQRES  23 a  373  GLN LEU THR PHE GLU GLU ILE ALA LYS SER ALA LYS ILE          
SEQRES  24 a  373  THR VAL ASN GLU VAL GLU LEU LEU VAL MET LYS ALA LEU          
SEQRES  25 a  373  SER VAL GLY LEU VAL LYS GLY SER ILE ASP GLU VAL ASP          
SEQRES  26 a  373  LYS ARG VAL HIS MET THR TRP VAL GLN PRO ARG VAL LEU          
SEQRES  27 a  373  ASP LEU GLN GLN ILE LYS GLY MET LYS ASP ARG LEU GLU          
SEQRES  28 a  373  PHE TRP CYS THR ASP VAL LYS SER MET GLU MET LEU VAL          
SEQRES  29 a  373  GLU HIS GLN ALA HIS ASP ILE LEU THR                          
SEQRES   1 b  191  MET VAL LEU GLU SER THR MET VAL CYS VAL ASP ASN SER          
SEQRES   2 b  191  GLU TYR MET ARG ASN GLY ASP PHE LEU PRO THR ARG LEU          
SEQRES   3 b  191  GLN ALA GLN GLN ASP ALA VAL ASN ILE VAL CYS HIS SER          
SEQRES   4 b  191  LYS THR ARG SER ASN PRO GLU ASN ASN VAL GLY LEU ILE          
SEQRES   5 b  191  THR LEU ALA ASN ASP CYS GLU VAL LEU THR THR LEU THR          
SEQRES   6 b  191  PRO ASP THR GLY ARG ILE LEU SER LYS LEU HIS THR VAL          
SEQRES   7 b  191  GLN PRO LYS GLY LYS ILE THR PHE CYS THR GLY ILE ARG          
SEQRES   8 b  191  VAL ALA HIS LEU ALA LEU LYS HIS ARG GLN GLY LYS ASN          
SEQRES   9 b  191  HIS LYS MET ARG ILE ILE ALA PHE VAL GLY SER PRO VAL          
SEQRES  10 b  191  GLU ASP ASN GLU LYS ASP LEU VAL LYS LEU ALA LYS ARG          
SEQRES  11 b  191  LEU LYS LYS GLU LYS VAL ASN VAL ASP ILE ILE ASN PHE          
SEQRES  12 b  191  GLY GLU GLU GLU VAL ASN THR GLU LYS LEU THR ALA PHE          
SEQRES  13 b  191  VAL ASN THR LEU ASN GLY LYS ASP GLY THR GLY SER HIS          
SEQRES  14 b  191  LEU VAL THR VAL PRO PRO GLY PRO SER LEU ALA ASP ALA          
SEQRES  15 b  191  LEU ILE SER SER PRO ILE LEU ALA GLY                          
SEQRES   1 c  287  ALA VAL ASP THR ALA GLU GLN VAL TYR ILE SER SER LEU          
SEQRES   2 c  287  ALA LEU LEU LYS MET LEU LYS HIS GLY ARG ALA GLY VAL          
SEQRES   3 c  287  PRO MET GLU VAL MET GLY LEU MET LEU GLY GLU PHE VAL          
SEQRES   4 c  287  ASP ASP TYR THR VAL ARG VAL ILE ASP VAL PHE ALA MET          
SEQRES   5 c  287  PRO GLN SER GLY THR GLY VAL SER VAL GLU ALA VAL ASP          
SEQRES   6 c  287  PRO VAL PHE GLN ALA LYS MET LEU ASP MET LEU LYS GLN          
SEQRES   7 c  287  THR GLY ARG PRO GLU MET VAL VAL GLY TRP TYR HIS SER          
SEQRES   8 c  287  HIS PRO GLY PHE GLY CYS TRP LEU SER GLY VAL ASP ILE          
SEQRES   9 c  287  ASN THR GLN GLN SER PHE GLU ALA LEU SER GLU ARG ALA          
SEQRES  10 c  287  VAL ALA VAL VAL VAL ASP PRO ILE GLN SER VAL LYS GLY          
SEQRES  11 c  287  LYS VAL VAL ILE ASP ALA PHE ARG LEU ILE ASN ALA ASN          
SEQRES  12 c  287  MET MET VAL LEU GLY HIS GLU PRO ARG GLN THR THR SER          
SEQRES  13 c  287  ASN LEU GLY HIS LEU ASN LYS PRO SER ILE GLN ALA LEU          
SEQRES  14 c  287  ILE HIS GLY LEU ASN ARG HIS TYR TYR SER ILE THR ILE          
SEQRES  15 c  287  ASN TYR ARG LYS ASN GLU LEU GLU GLN LYS MET LEU LEU          
SEQRES  16 c  287  ASN LEU HIS LYS LYS SER TRP MET GLU GLY LEU THR LEU          
SEQRES  17 c  287  GLN ASP TYR SER GLU HIS CYS LYS HIS ASN GLU SER VAL          
SEQRES  18 c  287  VAL LYS GLU MET LEU GLU LEU ALA LYS ASN TYR ASN LYS          
SEQRES  19 c  287  ALA VAL GLU GLU GLU ASP LYS MET THR PRO GLU GLN LEU          
SEQRES  20 c  287  ALA ILE LYS ASN VAL GLY LYS GLN ASP PRO LYS ARG HIS          
SEQRES  21 c  287  LEU GLU GLU HIS VAL ASP VAL LEU MET THR SER ASN ILE          
SEQRES  22 c  287  VAL GLN CYS LEU ALA ALA MET LEU ASP THR VAL VAL PHE          
SEQRES  23 c  287  LYS                                                          
SEQRES   1 d  257  MET TYR GLU GLN LEU LYS GLY GLU TRP ASN ARG LYS SER          
SEQRES   2 d  257  PRO ASN LEU SER LYS CYS GLY GLU GLU LEU GLY ARG LEU          
SEQRES   3 d  257  LYS LEU VAL LEU LEU GLU LEU ASN PHE LEU PRO THR THR          
SEQRES   4 d  257  GLY THR LYS LEU THR LYS GLN GLN LEU ILE LEU ALA ARG          
SEQRES   5 d  257  ASP ILE LEU GLU ILE GLY ALA GLN TRP SER ILE LEU ARG          
SEQRES   6 d  257  LYS ASP ILE PRO SER PHE GLU ARG TYR MET ALA GLN LEU          
SEQRES   7 d  257  LYS CYS TYR TYR PHE ASP TYR LYS GLU GLN LEU PRO GLU          
SEQRES   8 d  257  SER ALA TYR MET HIS GLN LEU LEU GLY LEU ASN LEU LEU          
SEQRES   9 d  257  PHE LEU LEU SER GLN ASN ARG VAL ALA GLU PHE HIS THR          
SEQRES  10 d  257  GLU LEU GLU ARG LEU PRO ALA LYS ASP ILE GLN THR ASN          
SEQRES  11 d  257  VAL TYR ILE LYS HIS PRO VAL SER LEU GLU GLN TYR LEU          
SEQRES  12 d  257  MET GLU GLY SER TYR ASN LYS VAL PHE LEU ALA LYS GLY          
SEQRES  13 d  257  ASN ILE PRO ALA GLU SER TYR THR PHE PHE ILE ASP ILE          
SEQRES  14 d  257  LEU LEU ASP THR ILE ARG ASP GLU ILE ALA GLY CYS ILE          
SEQRES  15 d  257  GLU LYS ALA TYR GLU LYS ILE LEU PHE THR GLU ALA THR          
SEQRES  16 d  257  ARG ILE LEU PHE PHE ASN THR PRO LYS LYS MET THR ASP          
SEQRES  17 d  257  TYR ALA LYS LYS ARG GLY TRP VAL LEU GLY PRO ASN ASN          
SEQRES  18 d  257  TYR TYR SER PHE ALA SER GLN GLN GLN LYS PRO GLU ASP          
SEQRES  19 d  257  THR THR ILE PRO SER THR GLU LEU ALA LYS GLN VAL ILE          
SEQRES  20 d  257  GLU TYR ALA ARG GLN LEU GLU MET ILE VAL                      
SEQRES   1 e   70  MET SER GLU LYS LYS GLN PRO VAL ASP LEU GLY LEU LEU          
SEQRES   2 e   70  GLU GLU ASP ASP GLU PHE GLU GLU PHE PRO ALA GLU ASP          
SEQRES   3 e   70  TRP ALA GLY LEU ASP GLU ASP GLU ASP ALA HIS VAL TRP          
SEQRES   4 e   70  GLU ASP ASN TRP ASP ASP ASP ASN VAL GLU ASP ASP PHE          
SEQRES   5 e   70  SER ASN GLN LEU ARG ALA GLU LEU GLU LYS HIS GLY TYR          
SEQRES   6 e   70  LYS MET GLU THR SER                                          
SEQRES   1 G  240  SER SER ALA GLY PHE ASP ARG HIS ILE THR ILE PHE SER          
SEQRES   2 G  240  PRO GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA PHE LYS          
SEQRES   3 G  240  ALA ILE ASN GLN GLY GLY LEU THR SER VAL ALA VAL ARG          
SEQRES   4 G  240  GLY LYS ASP CYS ALA VAL ILE VAL THR GLN LYS LYS VAL          
SEQRES   5 G  240  PRO ASP LYS LEU LEU ASP SER SER THR VAL THR HIS LEU          
SEQRES   6 G  240  PHE LYS ILE THR GLU ASN ILE GLY CYS VAL MET THR GLY          
SEQRES   7 G  240  MET THR ALA ASP SER ARG SER GLN VAL GLN ARG ALA ARG          
SEQRES   8 G  240  TYR GLU ALA ALA ASN TRP LYS TYR LYS TYR GLY TYR GLU          
SEQRES   9 G  240  ILE PRO VAL ASP MET LEU CYS LYS ARG ILE ALA ASP ILE          
SEQRES  10 G  240  SER GLN VAL TYR THR GLN ASN ALA GLU MET ARG PRO LEU          
SEQRES  11 G  240  GLY CYS CYS MET ILE LEU ILE GLY ILE ASP GLU GLU GLN          
SEQRES  12 G  240  GLY PRO GLN VAL TYR LYS CYS ASP PRO ALA GLY TYR TYR          
SEQRES  13 G  240  CYS GLY PHE LYS ALA THR ALA ALA GLY VAL LYS GLN THR          
SEQRES  14 G  240  GLU SER THR SER PHE LEU GLU LYS LYS VAL LYS LYS LYS          
SEQRES  15 G  240  PHE ASP TRP THR PHE GLU GLN THR VAL GLU THR ALA ILE          
SEQRES  16 G  240  THR CYS LEU SER THR VAL LEU SER ILE ASP PHE LYS PRO          
SEQRES  17 G  240  SER GLU ILE GLU VAL GLY VAL VAL THR VAL GLU ASN PRO          
SEQRES  18 G  240  LYS PHE ARG ILE LEU THR GLU ALA GLU ILE ASP ALA HIS          
SEQRES  19 G  240  LEU VAL ALA LEU ALA GLU                                      
SEQRES   1 H  232  GLU ARG GLY TYR SER PHE SER LEU THR THR PHE SER PRO          
SEQRES   2 H  232  SER GLY LYS LEU VAL GLN ILE GLU TYR ALA LEU ALA ALA          
SEQRES   3 H  232  VAL ALA GLY GLY ALA PRO SER VAL GLY ILE LYS ALA ALA          
SEQRES   4 H  232  ASN GLY VAL VAL LEU ALA THR GLU LYS LYS GLN LYS SER          
SEQRES   5 H  232  ILE LEU TYR ASP GLU ARG SER VAL HIS LYS VAL GLU PRO          
SEQRES   6 H  232  ILE THR LYS HIS ILE GLY LEU VAL TYR SER GLY MET GLY          
SEQRES   7 H  232  PRO ASP TYR ARG VAL LEU VAL HIS ARG ALA ARG LYS LEU          
SEQRES   8 H  232  ALA GLN GLN TYR TYR LEU VAL TYR GLN GLU PRO ILE PRO          
SEQRES   9 H  232  THR ALA GLN LEU VAL GLN ARG VAL ALA SER VAL MET GLN          
SEQRES  10 H  232  GLU TYR THR GLN SER GLY GLY VAL ARG PRO PHE GLY VAL          
SEQRES  11 H  232  SER LEU LEU ILE CYS GLY TRP ASN GLU GLY ARG PRO TYR          
SEQRES  12 H  232  LEU PHE GLN SER ASP PRO SER GLY ALA TYR PHE ALA TRP          
SEQRES  13 H  232  LYS ALA THR ALA MET GLY LYS ASN TYR VAL ASN GLY LYS          
SEQRES  14 H  232  THR PHE LEU GLU LYS ARG TYR ASN GLU ASP LEU GLU LEU          
SEQRES  15 H  232  GLU ASP ALA ILE HIS THR ALA ILE LEU THR LEU LYS GLU          
SEQRES  16 H  232  SER PHE GLU GLY GLN MET THR GLU ASP ASN ILE GLU VAL          
SEQRES  17 H  232  GLY ILE CYS ASN GLU ALA GLY PHE ARG ARG LEU THR PRO          
SEQRES  18 H  232  THR GLU VAL LYS ASP TYR LEU ALA ALA ILE ALA                  
SEQRES   1 I  250  SER ARG ARG TYR ASP SER ARG THR THR ILE PHE SER PRO          
SEQRES   2 I  250  GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA MET GLU ALA          
SEQRES   3 I  250  ILE GLY HIS ALA GLY THR CYS LEU GLY ILE LEU ALA ASN          
SEQRES   4 I  250  ASP GLY VAL LEU LEU ALA ALA GLU ARG ARG ASN ILE HIS          
SEQRES   5 I  250  LYS LEU LEU ASP GLU VAL PHE PHE SER GLU LYS ILE TYR          
SEQRES   6 I  250  LYS LEU ASN GLU ASP MET ALA CYS SER VAL ALA GLY ILE          
SEQRES   7 I  250  THR SER ASP ALA ASN VAL LEU THR ASN GLU LEU ARG LEU          
SEQRES   8 I  250  ILE ALA GLN ARG TYR LEU LEU GLN TYR GLN GLU PRO ILE          
SEQRES   9 I  250  PRO CYS GLU GLN LEU VAL THR ALA LEU CYS ASP ILE LYS          
SEQRES  10 I  250  GLN ALA TYR THR GLN PHE GLY GLY LYS ARG PRO PHE GLY          
SEQRES  11 I  250  VAL SER LEU LEU TYR ILE GLY TRP ASP LYS HIS TYR GLY          
SEQRES  12 I  250  PHE GLN LEU TYR GLN SER ASP PRO SER GLY ASN TYR GLY          
SEQRES  13 I  250  GLY TRP LYS ALA THR CYS ILE GLY ASN ASN SER ALA ALA          
SEQRES  14 I  250  ALA VAL SER MET LEU LYS GLN ASP TYR LYS GLU GLY GLU          
SEQRES  15 I  250  MET THR LEU LYS SER ALA LEU ALA LEU ALA ILE LYS VAL          
SEQRES  16 I  250  LEU ASN LYS THR MET ASP VAL SER LYS LEU SER ALA GLU          
SEQRES  17 I  250  LYS VAL GLU ILE ALA THR LEU THR ARG GLU ASN GLY LYS          
SEQRES  18 I  250  THR VAL ILE ARG VAL LEU LYS GLN LYS GLU VAL GLU GLN          
SEQRES  19 I  250  LEU ILE LYS LYS HIS GLU GLU GLU GLU ALA LYS ALA GLU          
SEQRES  20 I  250  ARG GLU LYS                                                  
SEQRES   1 J  243  SER TYR ASP ARG ALA ILE THR VAL PHE SER PRO ASP GLY          
SEQRES   2 J  243  HIS LEU PHE GLN VAL GLU TYR ALA GLN GLU ALA VAL LYS          
SEQRES   3 J  243  LYS GLY SER THR ALA VAL GLY VAL ARG GLY ARG ASP ILE          
SEQRES   4 J  243  VAL VAL LEU GLY VAL GLU LYS LYS SER VAL ALA LYS LEU          
SEQRES   5 J  243  GLN ASP GLU ARG THR VAL ARG LYS ILE CYS ALA LEU ASP          
SEQRES   6 J  243  ASP ASN VAL CYS MET ALA PHE ALA GLY LEU THR ALA ASP          
SEQRES   7 J  243  ALA ARG ILE VAL ILE ASN ARG ALA ARG VAL GLU CYS GLN          
SEQRES   8 J  243  SER HIS ARG LEU THR VAL GLU ASP PRO VAL THR VAL GLU          
SEQRES   9 J  243  TYR ILE THR ARG TYR ILE ALA SER LEU LYS GLN ARG TYR          
SEQRES  10 J  243  THR GLN SER ASN GLY ARG ARG PRO PHE GLY ILE SER ALA          
SEQRES  11 J  243  LEU ILE VAL GLY PHE ASP PHE ASP GLY THR PRO ARG LEU          
SEQRES  12 J  243  TYR GLN THR ASP PRO SER GLY THR TYR HIS ALA TRP LYS          
SEQRES  13 J  243  ALA ASN ALA ILE GLY ARG GLY ALA LYS SER VAL ARG GLU          
SEQRES  14 J  243  PHE LEU GLU LYS ASN TYR THR ASP GLU ALA ILE GLU THR          
SEQRES  15 J  243  ASP ASP LEU THR ILE LYS LEU VAL ILE LYS ALA LEU LEU          
SEQRES  16 J  243  GLU VAL VAL GLN SER GLY GLY LYS ASN ILE GLU LEU ALA          
SEQRES  17 J  243  VAL MET ARG ARG ASP GLN SER LEU LYS ILE LEU ASN PRO          
SEQRES  18 J  243  GLU GLU ILE GLU LYS TYR VAL ALA GLU ILE GLU LYS GLU          
SEQRES  19 J  243  LYS GLU GLU ASN GLU LYS LYS LYS GLN                          
SEQRES   1 K  234  TYR ASP ARG GLY VAL ASN THR PHE SER PRO GLU GLY ARG          
SEQRES   2 K  234  LEU PHE GLN VAL GLU TYR ALA ILE GLU ALA ILE LYS LEU          
SEQRES   3 K  234  GLY SER THR ALA ILE GLY ILE GLN THR SER GLU GLY VAL          
SEQRES   4 K  234  CYS LEU ALA VAL GLU LYS ARG ILE THR SER PRO LEU MET          
SEQRES   5 K  234  GLU PRO SER SER ILE GLU LYS ILE VAL GLU ILE ASP ALA          
SEQRES   6 K  234  HIS ILE GLY CYS ALA MET SER GLY LEU ILE ALA ASP ALA          
SEQRES   7 K  234  LYS THR LEU ILE ASP LYS ALA ARG VAL GLU THR GLN ASN          
SEQRES   8 K  234  HIS TRP PHE THR TYR ASN GLU THR MET THR VAL GLU SER          
SEQRES   9 K  234  VAL THR GLN ALA VAL SER ASN LEU ALA LEU GLN PHE GLY          
SEQRES  10 K  234  GLU GLU ASP ALA ASP PRO GLY ALA MET SER ARG PRO PHE          
SEQRES  11 K  234  GLY VAL ALA LEU LEU PHE GLY GLY VAL ASP GLU LYS GLY          
SEQRES  12 K  234  PRO GLN LEU PHE HIS MET ASP PRO SER GLY THR PHE VAL          
SEQRES  13 K  234  GLN CYS ASP ALA ARG ALA ILE GLY SER ALA SER GLU GLY          
SEQRES  14 K  234  ALA GLN SER SER LEU GLN GLU VAL TYR HIS LYS SER MET          
SEQRES  15 K  234  THR LEU LYS GLU ALA ILE LYS SER SER LEU ILE ILE LEU          
SEQRES  16 K  234  LYS GLN VAL MET GLU GLU LYS LEU ASN ALA THR ASN ILE          
SEQRES  17 K  234  GLU LEU ALA THR VAL GLN PRO GLY GLN ASN PHE HIS MET          
SEQRES  18 K  234  PHE THR LYS GLU GLU LEU GLU GLU VAL ILE LYS ASP ILE          
SEQRES   1 L  238  ASN GLN TYR ASP ASN ASP VAL THR VAL TRP SER PRO GLN          
SEQRES   2 L  238  GLY ARG ILE HIS GLN ILE GLU TYR ALA MET GLU ALA VAL          
SEQRES   3 L  238  LYS GLN GLY SER ALA THR VAL GLY LEU LYS SER LYS THR          
SEQRES   4 L  238  HIS ALA VAL LEU VAL ALA LEU LYS ARG ALA GLN SER GLU          
SEQRES   5 L  238  LEU ALA ALA HIS GLN LYS LYS ILE LEU HIS VAL ASP ASN          
SEQRES   6 L  238  HIS ILE GLY ILE SER ILE ALA GLY LEU THR ALA ASP ALA          
SEQRES   7 L  238  ARG LEU LEU CYS ASN PHE MET ARG GLN GLU CYS LEU ASP          
SEQRES   8 L  238  SER ARG PHE VAL PHE ASP ARG PRO LEU PRO VAL SER ARG          
SEQRES   9 L  238  LEU VAL SER LEU ILE GLY SER LYS THR GLN ILE PRO THR          
SEQRES  10 L  238  GLN ARG TYR GLY ARG ARG PRO TYR GLY VAL GLY LEU LEU          
SEQRES  11 L  238  ILE ALA GLY TYR ASP ASP MET GLY PRO HIS ILE PHE GLN          
SEQRES  12 L  238  THR CYS PRO SER ALA ASN TYR PHE ASP CYS ARG ALA MET          
SEQRES  13 L  238  SER ILE GLY ALA ARG SER GLN SER ALA ARG THR TYR LEU          
SEQRES  14 L  238  GLU ARG HIS MET SER GLU PHE MET GLU CYS ASN LEU ASN          
SEQRES  15 L  238  GLU LEU VAL LYS HIS GLY LEU ARG ALA LEU ARG GLU THR          
SEQRES  16 L  238  LEU PRO ALA GLU GLN ASP LEU THR THR LYS ASN VAL SER          
SEQRES  17 L  238  ILE GLY ILE VAL GLY LYS ASP LEU GLU PHE THR ILE TYR          
SEQRES  18 L  238  ASP ASP ASP ASP VAL SER PRO PHE LEU GLU GLY LEU GLU          
SEQRES  19 L  238  GLU ARG PRO GLN                                              
SEQRES   1 M  245  SER SER ILE GLY THR GLY TYR ASP LEU SER ALA SER THR          
SEQRES   2 M  245  PHE SER PRO ASP GLY ARG VAL PHE GLN VAL GLU TYR ALA          
SEQRES   3 M  245  MET LYS ALA VAL GLU ASN SER SER THR ALA ILE GLY ILE          
SEQRES   4 M  245  ARG CYS LYS ASP GLY VAL VAL PHE GLY VAL GLU LYS LEU          
SEQRES   5 M  245  VAL LEU SER LYS LEU TYR GLU GLU GLY SER ASN LYS ARG          
SEQRES   6 M  245  LEU PHE ASN VAL ASP ARG HIS VAL GLY MET ALA VAL ALA          
SEQRES   7 M  245  GLY LEU LEU ALA ASP ALA ARG SER LEU ALA ASP ILE ALA          
SEQRES   8 M  245  ARG GLU GLU ALA SER ASN PHE ARG SER ASN PHE GLY TYR          
SEQRES   9 M  245  ASN ILE PRO LEU LYS HIS LEU ALA ASP ARG VAL ALA MET          
SEQRES  10 M  245  TYR VAL HIS ALA TYR THR LEU TYR SER ALA VAL ARG PRO          
SEQRES  11 M  245  PHE GLY CYS SER PHE MET LEU GLY SER TYR SER VAL ASN          
SEQRES  12 M  245  ASP GLY ALA GLN LEU TYR MET ILE ASP PRO SER GLY VAL          
SEQRES  13 M  245  SER TYR GLY TYR TRP GLY CYS ALA ILE GLY LYS ALA ARG          
SEQRES  14 M  245  GLN ALA ALA LYS THR GLU ILE GLU LYS LEU GLN MET LYS          
SEQRES  15 M  245  GLU MET THR CYS ARG ASP ILE VAL LYS GLU VAL ALA LYS          
SEQRES  16 M  245  ILE ILE TYR ILE VAL HIS ASP GLU VAL LYS ASP LYS ALA          
SEQRES  17 M  245  PHE GLU LEU GLU LEU SER TRP VAL GLY GLU LEU THR ASN          
SEQRES  18 M  245  GLY ARG HIS GLU ILE VAL PRO LYS ASP ILE ARG GLU GLU          
SEQRES  19 M  245  ALA GLU LYS TYR ALA LYS GLU SER LEU LYS GLU                  
SEQRES   1 N  191  THR THR ILE MET ALA VAL GLN PHE ASP GLY GLY VAL VAL          
SEQRES   2 N  191  LEU GLY ALA ASP SER ARG THR THR THR GLY SER TYR ILE          
SEQRES   3 N  191  ALA ASN ARG VAL THR ASP LYS LEU THR PRO ILE HIS ASP          
SEQRES   4 N  191  ARG ILE PHE CYS CYS ARG SER GLY SER ALA ALA ASP THR          
SEQRES   5 N  191  GLN ALA VAL ALA ASP ALA VAL THR TYR GLN LEU GLY PHE          
SEQRES   6 N  191  HIS SER ILE GLU LEU ASN GLU PRO PRO LEU VAL HIS THR          
SEQRES   7 N  191  ALA ALA SER LEU PHE LYS GLU MET CYS TYR ARG TYR ARG          
SEQRES   8 N  191  GLU ASP LEU MET ALA GLY ILE ILE ILE ALA GLY TRP ASP          
SEQRES   9 N  191  PRO GLN GLU GLY GLY GLN VAL TYR SER VAL PRO MET GLY          
SEQRES  10 N  191  GLY MET MET VAL ARG GLN SER PHE ALA ILE GLY GLY SER          
SEQRES  11 N  191  GLY SER SER TYR ILE TYR GLY TYR VAL ASP ALA THR TYR          
SEQRES  12 N  191  ARG GLU GLY MET THR LYS GLU GLU CYS LEU GLN PHE THR          
SEQRES  13 N  191  ALA ASN ALA LEU ALA LEU ALA MET GLU ARG ASP GLY SER          
SEQRES  14 N  191  SER GLY GLY VAL ILE ARG LEU ALA ALA ILE ALA GLU SER          
SEQRES  15 N  191  GLY VAL GLU ARG GLN VAL LEU LEU GLY                          
SEQRES   1 O  220  THR THR ILE ALA GLY VAL VAL TYR LYS ASP GLY ILE VAL          
SEQRES   2 O  220  LEU GLY ALA ASP THR ARG ALA THR GLU GLY MET VAL VAL          
SEQRES   3 O  220  ALA ASP LYS ASN CYS SER LYS ILE HIS PHE ILE SER PRO          
SEQRES   4 O  220  ASN ILE TYR CYS CYS GLY ALA GLY THR ALA ALA ASP THR          
SEQRES   5 O  220  ASP MET THR THR GLN LEU ILE SER SER ASN LEU GLU LEU          
SEQRES   6 O  220  HIS SER LEU SER THR GLY ARG LEU PRO ARG VAL VAL THR          
SEQRES   7 O  220  ALA ASN ARG MET LEU LYS GLN MET LEU PHE ARG TYR GLN          
SEQRES   8 O  220  GLY TYR ILE GLY ALA ALA LEU VAL LEU GLY GLY VAL ASP          
SEQRES   9 O  220  VAL THR GLY PRO HIS LEU TYR SER ILE TYR PRO HIS GLY          
SEQRES  10 O  220  SER THR ASP LYS LEU PRO TYR VAL THR MET GLY SER GLY          
SEQRES  11 O  220  SER LEU ALA ALA MET ALA VAL PHE GLU ASP LYS PHE ARG          
SEQRES  12 O  220  PRO ASP MET GLU GLU GLU GLU ALA LYS ASN LEU VAL SER          
SEQRES  13 O  220  GLU ALA ILE ALA ALA GLY ILE PHE ASN ASP LEU GLY SER          
SEQRES  14 O  220  GLY SER ASN ILE ASP LEU CYS VAL ILE SER LYS ASN LYS          
SEQRES  15 O  220  LEU ASP PHE LEU ARG PRO TYR THR VAL PRO ASN LYS LYS          
SEQRES  16 O  220  GLY THR ARG LEU GLY ARG TYR ARG CYS GLU LYS GLY THR          
SEQRES  17 O  220  THR ALA VAL LEU THR GLU LYS ILE THR PRO LEU GLU              
SEQRES   1 P  204  SER ILE MET SER TYR ASN GLY GLY ALA VAL MET ALA MET          
SEQRES   2 P  204  LYS GLY LYS ASN CYS VAL ALA ILE ALA ALA ASP ARG ARG          
SEQRES   3 P  204  PHE GLY ILE GLN ALA GLN MET VAL THR THR ASP PHE GLN          
SEQRES   4 P  204  LYS ILE PHE PRO MET GLY ASP ARG LEU TYR ILE GLY LEU          
SEQRES   5 P  204  ALA GLY LEU ALA THR ASP VAL GLN THR VAL ALA GLN ARG          
SEQRES   6 P  204  LEU LYS PHE ARG LEU ASN LEU TYR GLU LEU LYS GLU GLY          
SEQRES   7 P  204  ARG GLN ILE LYS PRO TYR THR LEU MET SER MET VAL ALA          
SEQRES   8 P  204  ASN LEU LEU TYR GLU LYS ARG PHE GLY PRO TYR TYR THR          
SEQRES   9 P  204  GLU PRO VAL ILE ALA GLY LEU ASP PRO LYS THR PHE LYS          
SEQRES  10 P  204  PRO PHE ILE CYS SER LEU ASP LEU ILE GLY CYS PRO MET          
SEQRES  11 P  204  VAL THR ASP ASP PHE VAL VAL SER GLY THR CYS ALA GLU          
SEQRES  12 P  204  GLN MET TYR GLY MET CYS GLU SER LEU TRP GLU PRO ASN          
SEQRES  13 P  204  MET ASP PRO ASP HIS LEU PHE GLU THR ILE SER GLN ALA          
SEQRES  14 P  204  MET LEU ASN ALA VAL ASP ARG ASP ALA VAL SER GLY MET          
SEQRES  15 P  204  GLY VAL ILE VAL HIS ILE ILE GLU LYS ASP LYS ILE THR          
SEQRES  16 P  204  THR ARG THR LEU LYS ALA ARG MET ASP                          
SEQRES   1 Q  199  MET GLU TYR LEU ILE GLY ILE GLN GLY PRO ASP TYR VAL          
SEQRES   2 Q  199  LEU VAL ALA SER ASP ARG VAL ALA ALA SER ASN ILE VAL          
SEQRES   3 Q  199  GLN MET LYS ASP ASP HIS ASP LYS MET PHE LYS MET SER          
SEQRES   4 Q  199  GLU LYS ILE LEU LEU LEU CYS VAL GLY GLU ALA GLY ASP          
SEQRES   5 Q  199  THR VAL GLN PHE ALA GLU TYR ILE GLN LYS ASN VAL GLN          
SEQRES   6 Q  199  LEU TYR LYS MET ARG ASN GLY TYR GLU LEU SER PRO THR          
SEQRES   7 Q  199  ALA ALA ALA ASN PHE THR ARG ARG ASN LEU ALA ASP CYS          
SEQRES   8 Q  199  LEU ARG SER ARG THR PRO TYR HIS VAL ASN LEU LEU LEU          
SEQRES   9 Q  199  ALA GLY TYR ASP GLU HIS GLU GLY PRO ALA LEU TYR TYR          
SEQRES  10 Q  199  MET ASP TYR LEU ALA ALA LEU ALA LYS ALA PRO PHE ALA          
SEQRES  11 Q  199  ALA HIS GLY TYR GLY ALA PHE LEU THR LEU SER ILE LEU          
SEQRES  12 Q  199  ASP ARG TYR TYR THR PRO THR ILE SER ARG GLU ARG ALA          
SEQRES  13 Q  199  VAL GLU LEU LEU ARG LYS CYS LEU GLU GLU LEU GLN LYS          
SEQRES  14 Q  199  ARG PHE ILE LEU ASN LEU PRO THR PHE SER VAL ARG ILE          
SEQRES  15 Q  199  ILE ASP LYS ASN GLY ILE HIS ASP LEU ASP ASN ILE SER          
SEQRES  16 Q  199  PHE PRO LYS GLN                                              
SEQRES   1 R  201  THR THR THR LEU ALA PHE LYS PHE ARG HIS GLY VAL ILE          
SEQRES   2 R  201  VAL ALA ALA ASP SER ARG ALA THR ALA GLY ALA TYR ILE          
SEQRES   3 R  201  ALA SER GLN THR VAL LYS LYS VAL ILE GLU ILE ASN PRO          
SEQRES   4 R  201  TYR LEU LEU GLY THR MET ALA GLY GLY ALA ALA ASP CYS          
SEQRES   5 R  201  SER PHE TRP GLU ARG LEU LEU ALA ARG GLN CYS ARG ILE          
SEQRES   6 R  201  TYR GLU LEU ARG ASN LYS GLU ARG ILE SER VAL ALA ALA          
SEQRES   7 R  201  ALA SER LYS LEU LEU ALA ASN MET VAL TYR GLN TYR LYS          
SEQRES   8 R  201  GLY MET GLY LEU SER MET GLY THR MET ILE CYS GLY TRP          
SEQRES   9 R  201  ASP LYS ARG GLY PRO GLY LEU TYR TYR VAL ASP SER GLU          
SEQRES  10 R  201  GLY ASN ARG ILE SER GLY ALA THR PHE SER VAL GLY SER          
SEQRES  11 R  201  GLY SER VAL TYR ALA TYR GLY VAL MET ASP ARG GLY TYR          
SEQRES  12 R  201  SER TYR ASP LEU GLU VAL GLU GLN ALA TYR ASP LEU ALA          
SEQRES  13 R  201  ARG ARG ALA ILE TYR GLN ALA THR TYR ARG ASP ALA TYR          
SEQRES  14 R  201  SER GLY GLY ALA VAL ASN LEU TYR HIS VAL ARG GLU ASP          
SEQRES  15 R  201  GLY TRP ILE ARG VAL SER SER ASP ASN VAL ALA ASP LEU          
SEQRES  16 R  201  HIS GLU LYS TYR SER GLY                                      
SEQRES   1 S  213  ARG PHE SER PRO TYR VAL PHE ASN GLY GLY THR ILE LEU          
SEQRES   2 S  213  ALA ILE ALA GLY GLU ASP PHE ALA ILE VAL ALA SER ASP          
SEQRES   3 S  213  THR ARG LEU SER GLU GLY PHE SER ILE HIS THR ARG ASP          
SEQRES   4 S  213  SER PRO LYS CYS TYR LYS LEU THR ASP LYS THR VAL ILE          
SEQRES   5 S  213  GLY CYS SER GLY PHE HIS GLY ASP CYS LEU THR LEU THR          
SEQRES   6 S  213  LYS ILE ILE GLU ALA ARG LEU LYS MET TYR LYS HIS SER          
SEQRES   7 S  213  ASN ASN LYS ALA MET THR THR GLY ALA ILE ALA ALA MET          
SEQRES   8 S  213  LEU SER THR ILE LEU TYR SER ARG ARG PHE PHE PRO TYR          
SEQRES   9 S  213  TYR VAL TYR ASN ILE ILE GLY GLY LEU ASP GLU GLU GLY          
SEQRES  10 S  213  LYS GLY ALA VAL TYR SER PHE ASP PRO VAL GLY SER TYR          
SEQRES  11 S  213  GLN ARG ASP SER PHE LYS ALA GLY GLY SER ALA SER ALA          
SEQRES  12 S  213  MET LEU GLN PRO LEU LEU ASP ASN GLN VAL GLY PHE LYS          
SEQRES  13 S  213  ASN MET GLN ASN VAL GLU HIS VAL PRO LEU SER LEU ASP          
SEQRES  14 S  213  ARG ALA MET ARG LEU VAL LYS ASP VAL PHE ILE SER ALA          
SEQRES  15 S  213  ALA GLU ARG ASP VAL TYR THR GLY ASP ALA LEU ARG ILE          
SEQRES  16 S  213  CYS ILE VAL THR LYS GLU GLY ILE ARG GLU GLU THR VAL          
SEQRES  17 S  213  SER LEU ARG LYS ASP                                          
SEQRES   1 T  215  THR GLN ASN PRO MET VAL THR GLY THR SER VAL LEU GLY          
SEQRES   2 T  215  VAL LYS PHE GLU GLY GLY VAL VAL ILE ALA ALA ASP MET          
SEQRES   3 T  215  LEU GLY SER TYR GLY SER LEU ALA ARG PHE ARG ASN ILE          
SEQRES   4 T  215  SER ARG ILE MET ARG VAL ASN ASN SER THR MET LEU GLY          
SEQRES   5 T  215  ALA SER GLY ASP TYR ALA ASP PHE GLN TYR LEU LYS GLN          
SEQRES   6 T  215  VAL LEU GLY GLN MET VAL ILE ASP GLU GLU LEU LEU GLY          
SEQRES   7 T  215  ASP GLY HIS SER TYR SER PRO ARG ALA ILE HIS SER TRP          
SEQRES   8 T  215  LEU THR ARG ALA MET TYR SER ARG ARG SER LYS MET ASN          
SEQRES   9 T  215  PRO LEU TRP ASN THR MET VAL ILE GLY GLY TYR ALA ASP          
SEQRES  10 T  215  GLY GLU SER PHE LEU GLY TYR VAL ASP MET LEU GLY VAL          
SEQRES  11 T  215  ALA TYR GLU ALA PRO SER LEU ALA THR GLY TYR GLY ALA          
SEQRES  12 T  215  TYR LEU ALA GLN PRO LEU LEU ARG GLU VAL LEU GLU LYS          
SEQRES  13 T  215  GLN PRO VAL LEU SER GLN THR GLU ALA ARG ASP LEU VAL          
SEQRES  14 T  215  GLU ARG CYS MET ARG VAL LEU TYR TYR ARG ASP ALA ARG          
SEQRES  15 T  215  SER TYR ASN ARG PHE GLN ILE ALA THR VAL THR GLU LYS          
SEQRES  16 T  215  GLY VAL GLU ILE GLU GLY PRO LEU SER THR GLU THR ASN          
SEQRES  17 T  215  TRP ASP ILE ALA HIS MET ILE                                  
SEQRES   1 g  240  SER SER ALA GLY PHE ASP ARG HIS ILE THR ILE PHE SER          
SEQRES   2 g  240  PRO GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA PHE LYS          
SEQRES   3 g  240  ALA ILE ASN GLN GLY GLY LEU THR SER VAL ALA VAL ARG          
SEQRES   4 g  240  GLY LYS ASP CYS ALA VAL ILE VAL THR GLN LYS LYS VAL          
SEQRES   5 g  240  PRO ASP LYS LEU LEU ASP SER SER THR VAL THR HIS LEU          
SEQRES   6 g  240  PHE LYS ILE THR GLU ASN ILE GLY CYS VAL MET THR GLY          
SEQRES   7 g  240  MET THR ALA ASP SER ARG SER GLN VAL GLN ARG ALA ARG          
SEQRES   8 g  240  TYR GLU ALA ALA ASN TRP LYS TYR LYS TYR GLY TYR GLU          
SEQRES   9 g  240  ILE PRO VAL ASP MET LEU CYS LYS ARG ILE ALA ASP ILE          
SEQRES  10 g  240  SER GLN VAL TYR THR GLN ASN ALA GLU MET ARG PRO LEU          
SEQRES  11 g  240  GLY CYS CYS MET ILE LEU ILE GLY ILE ASP GLU GLU GLN          
SEQRES  12 g  240  GLY PRO GLN VAL TYR LYS CYS ASP PRO ALA GLY TYR TYR          
SEQRES  13 g  240  CYS GLY PHE LYS ALA THR ALA ALA GLY VAL LYS GLN THR          
SEQRES  14 g  240  GLU SER THR SER PHE LEU GLU LYS LYS VAL LYS LYS LYS          
SEQRES  15 g  240  PHE ASP TRP THR PHE GLU GLN THR VAL GLU THR ALA ILE          
SEQRES  16 g  240  THR CYS LEU SER THR VAL LEU SER ILE ASP PHE LYS PRO          
SEQRES  17 g  240  SER GLU ILE GLU VAL GLY VAL VAL THR VAL GLU ASN PRO          
SEQRES  18 g  240  LYS PHE ARG ILE LEU THR GLU ALA GLU ILE ASP ALA HIS          
SEQRES  19 g  240  LEU VAL ALA LEU ALA GLU                                      
SEQRES   1 h  232  GLU ARG GLY TYR SER PHE SER LEU THR THR PHE SER PRO          
SEQRES   2 h  232  SER GLY LYS LEU VAL GLN ILE GLU TYR ALA LEU ALA ALA          
SEQRES   3 h  232  VAL ALA GLY GLY ALA PRO SER VAL GLY ILE LYS ALA ALA          
SEQRES   4 h  232  ASN GLY VAL VAL LEU ALA THR GLU LYS LYS GLN LYS SER          
SEQRES   5 h  232  ILE LEU TYR ASP GLU ARG SER VAL HIS LYS VAL GLU PRO          
SEQRES   6 h  232  ILE THR LYS HIS ILE GLY LEU VAL TYR SER GLY MET GLY          
SEQRES   7 h  232  PRO ASP TYR ARG VAL LEU VAL HIS ARG ALA ARG LYS LEU          
SEQRES   8 h  232  ALA GLN GLN TYR TYR LEU VAL TYR GLN GLU PRO ILE PRO          
SEQRES   9 h  232  THR ALA GLN LEU VAL GLN ARG VAL ALA SER VAL MET GLN          
SEQRES  10 h  232  GLU TYR THR GLN SER GLY GLY VAL ARG PRO PHE GLY VAL          
SEQRES  11 h  232  SER LEU LEU ILE CYS GLY TRP ASN GLU GLY ARG PRO TYR          
SEQRES  12 h  232  LEU PHE GLN SER ASP PRO SER GLY ALA TYR PHE ALA TRP          
SEQRES  13 h  232  LYS ALA THR ALA MET GLY LYS ASN TYR VAL ASN GLY LYS          
SEQRES  14 h  232  THR PHE LEU GLU LYS ARG TYR ASN GLU ASP LEU GLU LEU          
SEQRES  15 h  232  GLU ASP ALA ILE HIS THR ALA ILE LEU THR LEU LYS GLU          
SEQRES  16 h  232  SER PHE GLU GLY GLN MET THR GLU ASP ASN ILE GLU VAL          
SEQRES  17 h  232  GLY ILE CYS ASN GLU ALA GLY PHE ARG ARG LEU THR PRO          
SEQRES  18 h  232  THR GLU VAL LYS ASP TYR LEU ALA ALA ILE ALA                  
SEQRES   1 i  250  SER ARG ARG TYR ASP SER ARG THR THR ILE PHE SER PRO          
SEQRES   2 i  250  GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA MET GLU ALA          
SEQRES   3 i  250  ILE GLY HIS ALA GLY THR CYS LEU GLY ILE LEU ALA ASN          
SEQRES   4 i  250  ASP GLY VAL LEU LEU ALA ALA GLU ARG ARG ASN ILE HIS          
SEQRES   5 i  250  LYS LEU LEU ASP GLU VAL PHE PHE SER GLU LYS ILE TYR          
SEQRES   6 i  250  LYS LEU ASN GLU ASP MET ALA CYS SER VAL ALA GLY ILE          
SEQRES   7 i  250  THR SER ASP ALA ASN VAL LEU THR ASN GLU LEU ARG LEU          
SEQRES   8 i  250  ILE ALA GLN ARG TYR LEU LEU GLN TYR GLN GLU PRO ILE          
SEQRES   9 i  250  PRO CYS GLU GLN LEU VAL THR ALA LEU CYS ASP ILE LYS          
SEQRES  10 i  250  GLN ALA TYR THR GLN PHE GLY GLY LYS ARG PRO PHE GLY          
SEQRES  11 i  250  VAL SER LEU LEU TYR ILE GLY TRP ASP LYS HIS TYR GLY          
SEQRES  12 i  250  PHE GLN LEU TYR GLN SER ASP PRO SER GLY ASN TYR GLY          
SEQRES  13 i  250  GLY TRP LYS ALA THR CYS ILE GLY ASN ASN SER ALA ALA          
SEQRES  14 i  250  ALA VAL SER MET LEU LYS GLN ASP TYR LYS GLU GLY GLU          
SEQRES  15 i  250  MET THR LEU LYS SER ALA LEU ALA LEU ALA ILE LYS VAL          
SEQRES  16 i  250  LEU ASN LYS THR MET ASP VAL SER LYS LEU SER ALA GLU          
SEQRES  17 i  250  LYS VAL GLU ILE ALA THR LEU THR ARG GLU ASN GLY LYS          
SEQRES  18 i  250  THR VAL ILE ARG VAL LEU LYS GLN LYS GLU VAL GLU GLN          
SEQRES  19 i  250  LEU ILE LYS LYS HIS GLU GLU GLU GLU ALA LYS ALA GLU          
SEQRES  20 i  250  ARG GLU LYS                                                  
SEQRES   1 j  243  SER TYR ASP ARG ALA ILE THR VAL PHE SER PRO ASP GLY          
SEQRES   2 j  243  HIS LEU PHE GLN VAL GLU TYR ALA GLN GLU ALA VAL LYS          
SEQRES   3 j  243  LYS GLY SER THR ALA VAL GLY VAL ARG GLY ARG ASP ILE          
SEQRES   4 j  243  VAL VAL LEU GLY VAL GLU LYS LYS SER VAL ALA LYS LEU          
SEQRES   5 j  243  GLN ASP GLU ARG THR VAL ARG LYS ILE CYS ALA LEU ASP          
SEQRES   6 j  243  ASP ASN VAL CYS MET ALA PHE ALA GLY LEU THR ALA ASP          
SEQRES   7 j  243  ALA ARG ILE VAL ILE ASN ARG ALA ARG VAL GLU CYS GLN          
SEQRES   8 j  243  SER HIS ARG LEU THR VAL GLU ASP PRO VAL THR VAL GLU          
SEQRES   9 j  243  TYR ILE THR ARG TYR ILE ALA SER LEU LYS GLN ARG TYR          
SEQRES  10 j  243  THR GLN SER ASN GLY ARG ARG PRO PHE GLY ILE SER ALA          
SEQRES  11 j  243  LEU ILE VAL GLY PHE ASP PHE ASP GLY THR PRO ARG LEU          
SEQRES  12 j  243  TYR GLN THR ASP PRO SER GLY THR TYR HIS ALA TRP LYS          
SEQRES  13 j  243  ALA ASN ALA ILE GLY ARG GLY ALA LYS SER VAL ARG GLU          
SEQRES  14 j  243  PHE LEU GLU LYS ASN TYR THR ASP GLU ALA ILE GLU THR          
SEQRES  15 j  243  ASP ASP LEU THR ILE LYS LEU VAL ILE LYS ALA LEU LEU          
SEQRES  16 j  243  GLU VAL VAL GLN SER GLY GLY LYS ASN ILE GLU LEU ALA          
SEQRES  17 j  243  VAL MET ARG ARG ASP GLN SER LEU LYS ILE LEU ASN PRO          
SEQRES  18 j  243  GLU GLU ILE GLU LYS TYR VAL ALA GLU ILE GLU LYS GLU          
SEQRES  19 j  243  LYS GLU GLU ASN GLU LYS LYS LYS GLN                          
SEQRES   1 k  234  TYR ASP ARG GLY VAL ASN THR PHE SER PRO GLU GLY ARG          
SEQRES   2 k  234  LEU PHE GLN VAL GLU TYR ALA ILE GLU ALA ILE LYS LEU          
SEQRES   3 k  234  GLY SER THR ALA ILE GLY ILE GLN THR SER GLU GLY VAL          
SEQRES   4 k  234  CYS LEU ALA VAL GLU LYS ARG ILE THR SER PRO LEU MET          
SEQRES   5 k  234  GLU PRO SER SER ILE GLU LYS ILE VAL GLU ILE ASP ALA          
SEQRES   6 k  234  HIS ILE GLY CYS ALA MET SER GLY LEU ILE ALA ASP ALA          
SEQRES   7 k  234  LYS THR LEU ILE ASP LYS ALA ARG VAL GLU THR GLN ASN          
SEQRES   8 k  234  HIS TRP PHE THR TYR ASN GLU THR MET THR VAL GLU SER          
SEQRES   9 k  234  VAL THR GLN ALA VAL SER ASN LEU ALA LEU GLN PHE GLY          
SEQRES  10 k  234  GLU GLU ASP ALA ASP PRO GLY ALA MET SER ARG PRO PHE          
SEQRES  11 k  234  GLY VAL ALA LEU LEU PHE GLY GLY VAL ASP GLU LYS GLY          
SEQRES  12 k  234  PRO GLN LEU PHE HIS MET ASP PRO SER GLY THR PHE VAL          
SEQRES  13 k  234  GLN CYS ASP ALA ARG ALA ILE GLY SER ALA SER GLU GLY          
SEQRES  14 k  234  ALA GLN SER SER LEU GLN GLU VAL TYR HIS LYS SER MET          
SEQRES  15 k  234  THR LEU LYS GLU ALA ILE LYS SER SER LEU ILE ILE LEU          
SEQRES  16 k  234  LYS GLN VAL MET GLU GLU LYS LEU ASN ALA THR ASN ILE          
SEQRES  17 k  234  GLU LEU ALA THR VAL GLN PRO GLY GLN ASN PHE HIS MET          
SEQRES  18 k  234  PHE THR LYS GLU GLU LEU GLU GLU VAL ILE LYS ASP ILE          
SEQRES   1 l  238  ASN GLN TYR ASP ASN ASP VAL THR VAL TRP SER PRO GLN          
SEQRES   2 l  238  GLY ARG ILE HIS GLN ILE GLU TYR ALA MET GLU ALA VAL          
SEQRES   3 l  238  LYS GLN GLY SER ALA THR VAL GLY LEU LYS SER LYS THR          
SEQRES   4 l  238  HIS ALA VAL LEU VAL ALA LEU LYS ARG ALA GLN SER GLU          
SEQRES   5 l  238  LEU ALA ALA HIS GLN LYS LYS ILE LEU HIS VAL ASP ASN          
SEQRES   6 l  238  HIS ILE GLY ILE SER ILE ALA GLY LEU THR ALA ASP ALA          
SEQRES   7 l  238  ARG LEU LEU CYS ASN PHE MET ARG GLN GLU CYS LEU ASP          
SEQRES   8 l  238  SER ARG PHE VAL PHE ASP ARG PRO LEU PRO VAL SER ARG          
SEQRES   9 l  238  LEU VAL SER LEU ILE GLY SER LYS THR GLN ILE PRO THR          
SEQRES  10 l  238  GLN ARG TYR GLY ARG ARG PRO TYR GLY VAL GLY LEU LEU          
SEQRES  11 l  238  ILE ALA GLY TYR ASP ASP MET GLY PRO HIS ILE PHE GLN          
SEQRES  12 l  238  THR CYS PRO SER ALA ASN TYR PHE ASP CYS ARG ALA MET          
SEQRES  13 l  238  SER ILE GLY ALA ARG SER GLN SER ALA ARG THR TYR LEU          
SEQRES  14 l  238  GLU ARG HIS MET SER GLU PHE MET GLU CYS ASN LEU ASN          
SEQRES  15 l  238  GLU LEU VAL LYS HIS GLY LEU ARG ALA LEU ARG GLU THR          
SEQRES  16 l  238  LEU PRO ALA GLU GLN ASP LEU THR THR LYS ASN VAL SER          
SEQRES  17 l  238  ILE GLY ILE VAL GLY LYS ASP LEU GLU PHE THR ILE TYR          
SEQRES  18 l  238  ASP ASP ASP ASP VAL SER PRO PHE LEU GLU GLY LEU GLU          
SEQRES  19 l  238  GLU ARG PRO GLN                                              
SEQRES   1 m  245  SER SER ILE GLY THR GLY TYR ASP LEU SER ALA SER THR          
SEQRES   2 m  245  PHE SER PRO ASP GLY ARG VAL PHE GLN VAL GLU TYR ALA          
SEQRES   3 m  245  MET LYS ALA VAL GLU ASN SER SER THR ALA ILE GLY ILE          
SEQRES   4 m  245  ARG CYS LYS ASP GLY VAL VAL PHE GLY VAL GLU LYS LEU          
SEQRES   5 m  245  VAL LEU SER LYS LEU TYR GLU GLU GLY SER ASN LYS ARG          
SEQRES   6 m  245  LEU PHE ASN VAL ASP ARG HIS VAL GLY MET ALA VAL ALA          
SEQRES   7 m  245  GLY LEU LEU ALA ASP ALA ARG SER LEU ALA ASP ILE ALA          
SEQRES   8 m  245  ARG GLU GLU ALA SER ASN PHE ARG SER ASN PHE GLY TYR          
SEQRES   9 m  245  ASN ILE PRO LEU LYS HIS LEU ALA ASP ARG VAL ALA MET          
SEQRES  10 m  245  TYR VAL HIS ALA TYR THR LEU TYR SER ALA VAL ARG PRO          
SEQRES  11 m  245  PHE GLY CYS SER PHE MET LEU GLY SER TYR SER VAL ASN          
SEQRES  12 m  245  ASP GLY ALA GLN LEU TYR MET ILE ASP PRO SER GLY VAL          
SEQRES  13 m  245  SER TYR GLY TYR TRP GLY CYS ALA ILE GLY LYS ALA ARG          
SEQRES  14 m  245  GLN ALA ALA LYS THR GLU ILE GLU LYS LEU GLN MET LYS          
SEQRES  15 m  245  GLU MET THR CYS ARG ASP ILE VAL LYS GLU VAL ALA LYS          
SEQRES  16 m  245  ILE ILE TYR ILE VAL HIS ASP GLU VAL LYS ASP LYS ALA          
SEQRES  17 m  245  PHE GLU LEU GLU LEU SER TRP VAL GLY GLU LEU THR ASN          
SEQRES  18 m  245  GLY ARG HIS GLU ILE VAL PRO LYS ASP ILE ARG GLU GLU          
SEQRES  19 m  245  ALA GLU LYS TYR ALA LYS GLU SER LEU LYS GLU                  
SEQRES   1 n  191  THR THR ILE MET ALA VAL GLN PHE ASP GLY GLY VAL VAL          
SEQRES   2 n  191  LEU GLY ALA ASP SER ARG THR THR THR GLY SER TYR ILE          
SEQRES   3 n  191  ALA ASN ARG VAL THR ASP LYS LEU THR PRO ILE HIS ASP          
SEQRES   4 n  191  ARG ILE PHE CYS CYS ARG SER GLY SER ALA ALA ASP THR          
SEQRES   5 n  191  GLN ALA VAL ALA ASP ALA VAL THR TYR GLN LEU GLY PHE          
SEQRES   6 n  191  HIS SER ILE GLU LEU ASN GLU PRO PRO LEU VAL HIS THR          
SEQRES   7 n  191  ALA ALA SER LEU PHE LYS GLU MET CYS TYR ARG TYR ARG          
SEQRES   8 n  191  GLU ASP LEU MET ALA GLY ILE ILE ILE ALA GLY TRP ASP          
SEQRES   9 n  191  PRO GLN GLU GLY GLY GLN VAL TYR SER VAL PRO MET GLY          
SEQRES  10 n  191  GLY MET MET VAL ARG GLN SER PHE ALA ILE GLY GLY SER          
SEQRES  11 n  191  GLY SER SER TYR ILE TYR GLY TYR VAL ASP ALA THR TYR          
SEQRES  12 n  191  ARG GLU GLY MET THR LYS GLU GLU CYS LEU GLN PHE THR          
SEQRES  13 n  191  ALA ASN ALA LEU ALA LEU ALA MET GLU ARG ASP GLY SER          
SEQRES  14 n  191  SER GLY GLY VAL ILE ARG LEU ALA ALA ILE ALA GLU SER          
SEQRES  15 n  191  GLY VAL GLU ARG GLN VAL LEU LEU GLY                          
SEQRES   1 o  220  THR THR ILE ALA GLY VAL VAL TYR LYS ASP GLY ILE VAL          
SEQRES   2 o  220  LEU GLY ALA ASP THR ARG ALA THR GLU GLY MET VAL VAL          
SEQRES   3 o  220  ALA ASP LYS ASN CYS SER LYS ILE HIS PHE ILE SER PRO          
SEQRES   4 o  220  ASN ILE TYR CYS CYS GLY ALA GLY THR ALA ALA ASP THR          
SEQRES   5 o  220  ASP MET THR THR GLN LEU ILE SER SER ASN LEU GLU LEU          
SEQRES   6 o  220  HIS SER LEU SER THR GLY ARG LEU PRO ARG VAL VAL THR          
SEQRES   7 o  220  ALA ASN ARG MET LEU LYS GLN MET LEU PHE ARG TYR GLN          
SEQRES   8 o  220  GLY TYR ILE GLY ALA ALA LEU VAL LEU GLY GLY VAL ASP          
SEQRES   9 o  220  VAL THR GLY PRO HIS LEU TYR SER ILE TYR PRO HIS GLY          
SEQRES  10 o  220  SER THR ASP LYS LEU PRO TYR VAL THR MET GLY SER GLY          
SEQRES  11 o  220  SER LEU ALA ALA MET ALA VAL PHE GLU ASP LYS PHE ARG          
SEQRES  12 o  220  PRO ASP MET GLU GLU GLU GLU ALA LYS ASN LEU VAL SER          
SEQRES  13 o  220  GLU ALA ILE ALA ALA GLY ILE PHE ASN ASP LEU GLY SER          
SEQRES  14 o  220  GLY SER ASN ILE ASP LEU CYS VAL ILE SER LYS ASN LYS          
SEQRES  15 o  220  LEU ASP PHE LEU ARG PRO TYR THR VAL PRO ASN LYS LYS          
SEQRES  16 o  220  GLY THR ARG LEU GLY ARG TYR ARG CYS GLU LYS GLY THR          
SEQRES  17 o  220  THR ALA VAL LEU THR GLU LYS ILE THR PRO LEU GLU              
SEQRES   1 p  204  SER ILE MET SER TYR ASN GLY GLY ALA VAL MET ALA MET          
SEQRES   2 p  204  LYS GLY LYS ASN CYS VAL ALA ILE ALA ALA ASP ARG ARG          
SEQRES   3 p  204  PHE GLY ILE GLN ALA GLN MET VAL THR THR ASP PHE GLN          
SEQRES   4 p  204  LYS ILE PHE PRO MET GLY ASP ARG LEU TYR ILE GLY LEU          
SEQRES   5 p  204  ALA GLY LEU ALA THR ASP VAL GLN THR VAL ALA GLN ARG          
SEQRES   6 p  204  LEU LYS PHE ARG LEU ASN LEU TYR GLU LEU LYS GLU GLY          
SEQRES   7 p  204  ARG GLN ILE LYS PRO TYR THR LEU MET SER MET VAL ALA          
SEQRES   8 p  204  ASN LEU LEU TYR GLU LYS ARG PHE GLY PRO TYR TYR THR          
SEQRES   9 p  204  GLU PRO VAL ILE ALA GLY LEU ASP PRO LYS THR PHE LYS          
SEQRES  10 p  204  PRO PHE ILE CYS SER LEU ASP LEU ILE GLY CYS PRO MET          
SEQRES  11 p  204  VAL THR ASP ASP PHE VAL VAL SER GLY THR CYS ALA GLU          
SEQRES  12 p  204  GLN MET TYR GLY MET CYS GLU SER LEU TRP GLU PRO ASN          
SEQRES  13 p  204  MET ASP PRO ASP HIS LEU PHE GLU THR ILE SER GLN ALA          
SEQRES  14 p  204  MET LEU ASN ALA VAL ASP ARG ASP ALA VAL SER GLY MET          
SEQRES  15 p  204  GLY VAL ILE VAL HIS ILE ILE GLU LYS ASP LYS ILE THR          
SEQRES  16 p  204  THR ARG THR LEU LYS ALA ARG MET ASP                          
SEQRES   1 q  199  MET GLU TYR LEU ILE GLY ILE GLN GLY PRO ASP TYR VAL          
SEQRES   2 q  199  LEU VAL ALA SER ASP ARG VAL ALA ALA SER ASN ILE VAL          
SEQRES   3 q  199  GLN MET LYS ASP ASP HIS ASP LYS MET PHE LYS MET SER          
SEQRES   4 q  199  GLU LYS ILE LEU LEU LEU CYS VAL GLY GLU ALA GLY ASP          
SEQRES   5 q  199  THR VAL GLN PHE ALA GLU TYR ILE GLN LYS ASN VAL GLN          
SEQRES   6 q  199  LEU TYR LYS MET ARG ASN GLY TYR GLU LEU SER PRO THR          
SEQRES   7 q  199  ALA ALA ALA ASN PHE THR ARG ARG ASN LEU ALA ASP CYS          
SEQRES   8 q  199  LEU ARG SER ARG THR PRO TYR HIS VAL ASN LEU LEU LEU          
SEQRES   9 q  199  ALA GLY TYR ASP GLU HIS GLU GLY PRO ALA LEU TYR TYR          
SEQRES  10 q  199  MET ASP TYR LEU ALA ALA LEU ALA LYS ALA PRO PHE ALA          
SEQRES  11 q  199  ALA HIS GLY TYR GLY ALA PHE LEU THR LEU SER ILE LEU          
SEQRES  12 q  199  ASP ARG TYR TYR THR PRO THR ILE SER ARG GLU ARG ALA          
SEQRES  13 q  199  VAL GLU LEU LEU ARG LYS CYS LEU GLU GLU LEU GLN LYS          
SEQRES  14 q  199  ARG PHE ILE LEU ASN LEU PRO THR PHE SER VAL ARG ILE          
SEQRES  15 q  199  ILE ASP LYS ASN GLY ILE HIS ASP LEU ASP ASN ILE SER          
SEQRES  16 q  199  PHE PRO LYS GLN                                              
SEQRES   1 r  201  THR THR THR LEU ALA PHE LYS PHE ARG HIS GLY VAL ILE          
SEQRES   2 r  201  VAL ALA ALA ASP SER ARG ALA THR ALA GLY ALA TYR ILE          
SEQRES   3 r  201  ALA SER GLN THR VAL LYS LYS VAL ILE GLU ILE ASN PRO          
SEQRES   4 r  201  TYR LEU LEU GLY THR MET ALA GLY GLY ALA ALA ASP CYS          
SEQRES   5 r  201  SER PHE TRP GLU ARG LEU LEU ALA ARG GLN CYS ARG ILE          
SEQRES   6 r  201  TYR GLU LEU ARG ASN LYS GLU ARG ILE SER VAL ALA ALA          
SEQRES   7 r  201  ALA SER LYS LEU LEU ALA ASN MET VAL TYR GLN TYR LYS          
SEQRES   8 r  201  GLY MET GLY LEU SER MET GLY THR MET ILE CYS GLY TRP          
SEQRES   9 r  201  ASP LYS ARG GLY PRO GLY LEU TYR TYR VAL ASP SER GLU          
SEQRES  10 r  201  GLY ASN ARG ILE SER GLY ALA THR PHE SER VAL GLY SER          
SEQRES  11 r  201  GLY SER VAL TYR ALA TYR GLY VAL MET ASP ARG GLY TYR          
SEQRES  12 r  201  SER TYR ASP LEU GLU VAL GLU GLN ALA TYR ASP LEU ALA          
SEQRES  13 r  201  ARG ARG ALA ILE TYR GLN ALA THR TYR ARG ASP ALA TYR          
SEQRES  14 r  201  SER GLY GLY ALA VAL ASN LEU TYR HIS VAL ARG GLU ASP          
SEQRES  15 r  201  GLY TRP ILE ARG VAL SER SER ASP ASN VAL ALA ASP LEU          
SEQRES  16 r  201  HIS GLU LYS TYR SER GLY                                      
SEQRES   1 s  213  ARG PHE SER PRO TYR VAL PHE ASN GLY GLY THR ILE LEU          
SEQRES   2 s  213  ALA ILE ALA GLY GLU ASP PHE ALA ILE VAL ALA SER ASP          
SEQRES   3 s  213  THR ARG LEU SER GLU GLY PHE SER ILE HIS THR ARG ASP          
SEQRES   4 s  213  SER PRO LYS CYS TYR LYS LEU THR ASP LYS THR VAL ILE          
SEQRES   5 s  213  GLY CYS SER GLY PHE HIS GLY ASP CYS LEU THR LEU THR          
SEQRES   6 s  213  LYS ILE ILE GLU ALA ARG LEU LYS MET TYR LYS HIS SER          
SEQRES   7 s  213  ASN ASN LYS ALA MET THR THR GLY ALA ILE ALA ALA MET          
SEQRES   8 s  213  LEU SER THR ILE LEU TYR SER ARG ARG PHE PHE PRO TYR          
SEQRES   9 s  213  TYR VAL TYR ASN ILE ILE GLY GLY LEU ASP GLU GLU GLY          
SEQRES  10 s  213  LYS GLY ALA VAL TYR SER PHE ASP PRO VAL GLY SER TYR          
SEQRES  11 s  213  GLN ARG ASP SER PHE LYS ALA GLY GLY SER ALA SER ALA          
SEQRES  12 s  213  MET LEU GLN PRO LEU LEU ASP ASN GLN VAL GLY PHE LYS          
SEQRES  13 s  213  ASN MET GLN ASN VAL GLU HIS VAL PRO LEU SER LEU ASP          
SEQRES  14 s  213  ARG ALA MET ARG LEU VAL LYS ASP VAL PHE ILE SER ALA          
SEQRES  15 s  213  ALA GLU ARG ASP VAL TYR THR GLY ASP ALA LEU ARG ILE          
SEQRES  16 s  213  CYS ILE VAL THR LYS GLU GLY ILE ARG GLU GLU THR VAL          
SEQRES  17 s  213  SER LEU ARG LYS ASP                                          
SEQRES   1 t  215  THR GLN ASN PRO MET VAL THR GLY THR SER VAL LEU GLY          
SEQRES   2 t  215  VAL LYS PHE GLU GLY GLY VAL VAL ILE ALA ALA ASP MET          
SEQRES   3 t  215  LEU GLY SER TYR GLY SER LEU ALA ARG PHE ARG ASN ILE          
SEQRES   4 t  215  SER ARG ILE MET ARG VAL ASN ASN SER THR MET LEU GLY          
SEQRES   5 t  215  ALA SER GLY ASP TYR ALA ASP PHE GLN TYR LEU LYS GLN          
SEQRES   6 t  215  VAL LEU GLY GLN MET VAL ILE ASP GLU GLU LEU LEU GLY          
SEQRES   7 t  215  ASP GLY HIS SER TYR SER PRO ARG ALA ILE HIS SER TRP          
SEQRES   8 t  215  LEU THR ARG ALA MET TYR SER ARG ARG SER LYS MET ASN          
SEQRES   9 t  215  PRO LEU TRP ASN THR MET VAL ILE GLY GLY TYR ALA ASP          
SEQRES  10 t  215  GLY GLU SER PHE LEU GLY TYR VAL ASP MET LEU GLY VAL          
SEQRES  11 t  215  ALA TYR GLU ALA PRO SER LEU ALA THR GLY TYR GLY ALA          
SEQRES  12 t  215  TYR LEU ALA GLN PRO LEU LEU ARG GLU VAL LEU GLU LYS          
SEQRES  13 t  215  GLN PRO VAL LEU SER GLN THR GLU ALA ARG ASP LEU VAL          
SEQRES  14 t  215  GLU ARG CYS MET ARG VAL LEU TYR TYR ARG ASP ALA ARG          
SEQRES  15 t  215  SER TYR ASN ARG PHE GLN ILE ALA THR VAL THR GLU LYS          
SEQRES  16 t  215  GLY VAL GLU ILE GLU GLY PRO LEU SER THR GLU THR ASN          
SEQRES  17 t  215  TRP ASP ILE ALA HIS MET ILE                                  
SEQRES   1 A  399  THR TYR GLY GLN SER THR TYR SER ARG GLN ILE LYS GLN          
SEQRES   2 A  399  VAL GLU ASP ASP ILE GLN GLN LEU LEU LYS LYS ILE ASN          
SEQRES   3 A  399  GLU LEU THR GLY ILE LYS GLU SER ASP THR GLY LEU ALA          
SEQRES   4 A  399  PRO PRO ALA LEU TRP ASP LEU ALA ALA ASP LYS GLN THR          
SEQRES   5 A  399  LEU GLN SER GLU GLN PRO LEU GLN VAL ALA ARG CYS THR          
SEQRES   6 A  399  LYS ILE ILE ASN ALA ASP SER GLU ASP PRO LYS TYR ILE          
SEQRES   7 A  399  ILE ASN VAL LYS GLN PHE ALA LYS PHE VAL VAL ASP LEU          
SEQRES   8 A  399  SER ASP GLN VAL ALA PRO THR ASP ILE GLU GLU GLY MET          
SEQRES   9 A  399  ARG VAL GLY VAL ASP ARG ASN LYS TYR GLN ILE HIS ILE          
SEQRES  10 A  399  PRO LEU PRO PRO LYS ILE ASP PRO THR VAL THR MET MET          
SEQRES  11 A  399  GLN VAL GLU GLU LYS PRO ASP VAL THR TYR SER ASP VAL          
SEQRES  12 A  399  GLY GLY CYS LYS GLU GLN ILE GLU LYS LEU ARG GLU VAL          
SEQRES  13 A  399  VAL GLU THR PRO LEU LEU HIS PRO GLU ARG PHE VAL ASN          
SEQRES  14 A  399  LEU GLY ILE GLU PRO PRO LYS GLY VAL LEU LEU PHE GLY          
SEQRES  15 A  399  PRO PRO GLY THR GLY LYS THR LEU CYS ALA ARG ALA VAL          
SEQRES  16 A  399  ALA ASN ARG THR ASP ALA CYS PHE ILE ARG VAL ILE GLY          
SEQRES  17 A  399  SER GLU LEU VAL GLN LYS TYR VAL GLY GLU GLY ALA ARG          
SEQRES  18 A  399  MET VAL ARG GLU LEU PHE GLU MET ALA ARG THR LYS LYS          
SEQRES  19 A  399  ALA CYS LEU ILE PHE PHE ASP GLU ILE ASP ALA ILE GLY          
SEQRES  20 A  399  GLY ALA ARG PHE ASP ASP GLY ALA GLY GLY ASP ASN GLU          
SEQRES  21 A  399  VAL GLN ARG THR MET LEU GLU LEU ILE ASN GLN LEU ASP          
SEQRES  22 A  399  GLY PHE ASP PRO ARG GLY ASN ILE LYS VAL LEU MET ALA          
SEQRES  23 A  399  THR ASN ARG PRO ASP THR LEU ASP PRO ALA LEU MET ARG          
SEQRES  24 A  399  PRO GLY ARG LEU ASP ARG LYS ILE GLU PHE SER LEU PRO          
SEQRES  25 A  399  ASP LEU GLU GLY ARG THR HIS ILE PHE LYS ILE HIS ALA          
SEQRES  26 A  399  ARG SER MET SER VAL GLU ARG ASP ILE ARG PHE GLU LEU          
SEQRES  27 A  399  LEU ALA ARG LEU CYS PRO ASN SER THR GLY ALA GLU ILE          
SEQRES  28 A  399  ARG SER VAL CYS THR GLU ALA GLY MET PHE ALA ILE ARG          
SEQRES  29 A  399  ALA ARG ARG LYS ILE ALA THR GLU LYS ASP PHE LEU GLU          
SEQRES  30 A  399  ALA VAL ASN LYS VAL ILE LYS SER TYR ALA LYS PHE SER          
SEQRES  31 A  399  ALA THR PRO ARG TYR MET THR TYR ASN                          
SEQRES   1 B  389  VAL THR PRO HIS THR GLN CYS ARG LEU LYS LEU LEU LYS          
SEQRES   2 B  389  LEU GLU ARG ILE LYS ASP TYR LEU LEU MET GLU GLU GLU          
SEQRES   3 B  389  PHE ILE ARG ASN GLN GLU GLN MET LYS PRO LEU GLU GLU          
SEQRES   4 B  389  LYS GLN GLU GLU GLU ARG SER LYS VAL ASP ASP LEU ARG          
SEQRES   5 B  389  GLY THR PRO MET SER VAL GLY THR LEU GLU GLU ILE ILE          
SEQRES   6 B  389  ASP ASP ASN HIS ALA ILE VAL SER THR SER VAL GLY SER          
SEQRES   7 B  389  GLU HIS TYR VAL SER ILE LEU SER PHE VAL ASP LYS ASP          
SEQRES   8 B  389  LEU LEU GLU PRO GLY CYS SER VAL LEU LEU ASN HIS LYS          
SEQRES   9 B  389  VAL HIS ALA VAL ILE GLY VAL LEU MET ASP ASP THR ASP          
SEQRES  10 B  389  PRO LEU VAL THR VAL MET LYS VAL GLU LYS ALA PRO GLN          
SEQRES  11 B  389  GLU THR TYR ALA ASP ILE GLY GLY LEU ASP ASN GLN ILE          
SEQRES  12 B  389  GLN GLU ILE LYS GLU SER VAL GLU LEU PRO LEU THR HIS          
SEQRES  13 B  389  PRO GLU TYR TYR GLU GLU MET GLY ILE LYS PRO PRO LYS          
SEQRES  14 B  389  GLY VAL ILE LEU TYR GLY PRO PRO GLY THR GLY LYS THR          
SEQRES  15 B  389  LEU LEU ALA LYS ALA VAL ALA ASN GLN THR SER ALA THR          
SEQRES  16 B  389  PHE LEU ARG VAL VAL GLY SER GLU LEU ILE GLN LYS TYR          
SEQRES  17 B  389  LEU GLY ASP GLY PRO LYS LEU VAL ARG GLU LEU PHE ARG          
SEQRES  18 B  389  VAL ALA GLU GLU HIS ALA PRO SER ILE VAL PHE ILE ASP          
SEQRES  19 B  389  GLU ILE ASP ALA ILE GLY THR LYS ARG TYR ASP SER ASN          
SEQRES  20 B  389  SER GLY GLY GLU ARG GLU ILE GLN ARG THR MET LEU GLU          
SEQRES  21 B  389  LEU LEU ASN GLN LEU ASP GLY PHE ASP SER ARG GLY ASP          
SEQRES  22 B  389  VAL LYS VAL ILE MET ALA THR ASN ARG ILE GLU THR LEU          
SEQRES  23 B  389  ASP PRO ALA LEU ILE ARG PRO GLY ARG ILE ASP ARG LYS          
SEQRES  24 B  389  ILE GLU PHE PRO LEU PRO ASP GLU LYS THR LYS LYS ARG          
SEQRES  25 B  389  ILE PHE GLN ILE HIS THR SER ARG MET THR LEU ALA ASP          
SEQRES  26 B  389  ASP VAL THR LEU ASP ASP LEU ILE MET ALA LYS ASP ASP          
SEQRES  27 B  389  LEU SER GLY ALA ASP ILE LYS ALA ILE CYS THR GLU ALA          
SEQRES  28 B  389  GLY LEU MET ALA LEU ARG GLU ARG ARG MET LYS VAL THR          
SEQRES  29 B  389  ASN GLU ASP PHE LYS LYS SER LYS GLU ASN VAL LEU TYR          
SEQRES  30 B  389  LYS LYS GLN GLU GLY THR PRO GLU GLY LEU TYR LEU              
SEQRES   1 C  392  LEU GLU GLU GLY LYS ALA GLY SER GLY LEU ARG GLN TYR          
SEQRES   2 C  392  TYR LEU SER LYS ILE GLU GLU LEU GLN LEU ILE VAL ASN          
SEQRES   3 C  392  ASP LYS SER GLN ASN LEU ARG ARG LEU GLN ALA GLN ARG          
SEQRES   4 C  392  ASN GLU LEU ASN ALA LYS VAL ARG LEU LEU ARG GLU GLU          
SEQRES   5 C  392  LEU GLN LEU LEU GLN GLU GLN GLY SER TYR VAL GLY GLU          
SEQRES   6 C  392  VAL VAL ARG ALA MET ASP LYS LYS LYS VAL LEU VAL LYS          
SEQRES   7 C  392  VAL HIS PRO GLU GLY LYS PHE VAL VAL ASP VAL ASP LYS          
SEQRES   8 C  392  ASN ILE ASP ILE ASN ASP VAL THR PRO ASN CYS ARG VAL          
SEQRES   9 C  392  ALA LEU ARG ASN ASP SER TYR THR LEU HIS LYS ILE LEU          
SEQRES  10 C  392  PRO ASN LYS VAL ASP PRO LEU VAL SER LEU MET MET VAL          
SEQRES  11 C  392  GLU LYS VAL PRO ASP SER THR TYR GLU MET ILE GLY GLY          
SEQRES  12 C  392  LEU ASP LYS GLN ILE LYS GLU ILE LYS GLU VAL ILE GLU          
SEQRES  13 C  392  LEU PRO VAL LYS HIS PRO GLU LEU PHE GLU ALA LEU GLY          
SEQRES  14 C  392  ILE ALA GLN PRO LYS GLY VAL LEU LEU TYR GLY PRO PRO          
SEQRES  15 C  392  GLY THR GLY LYS THR LEU LEU ALA ARG ALA VAL ALA HIS          
SEQRES  16 C  392  HIS THR ASP CYS THR PHE ILE ARG VAL SER GLY SER GLU          
SEQRES  17 C  392  LEU VAL GLN LYS PHE ILE GLY GLU GLY ALA ARG MET VAL          
SEQRES  18 C  392  ARG GLU LEU PHE VAL MET ALA ARG GLU HIS ALA PRO SER          
SEQRES  19 C  392  ILE ILE PHE MET ASP GLU ILE ASP SER ILE GLY SER SER          
SEQRES  20 C  392  ARG LEU GLU GLY GLY SER GLY GLY ASP SER GLU VAL GLN          
SEQRES  21 C  392  ARG THR MET LEU GLU LEU LEU ASN GLN LEU ASP GLY PHE          
SEQRES  22 C  392  GLU ALA THR LYS ASN ILE LYS VAL ILE MET ALA THR ASN          
SEQRES  23 C  392  ARG ILE ASP ILE LEU ASP SER ALA LEU LEU ARG PRO GLY          
SEQRES  24 C  392  ARG ILE ASP ARG LYS ILE GLU PHE PRO PRO PRO ASN GLU          
SEQRES  25 C  392  GLU ALA ARG LEU ASP ILE LEU LYS ILE HIS SER ARG LYS          
SEQRES  26 C  392  MET ASN LEU THR ARG GLY ILE ASN LEU ARG LYS ILE ALA          
SEQRES  27 C  392  GLU LEU MET PRO GLY ALA SER GLY ALA GLU VAL LYS GLY          
SEQRES  28 C  392  VAL CYS THR GLU ALA GLY MET TYR ALA LEU ARG GLU ARG          
SEQRES  29 C  392  ARG VAL HIS VAL THR GLN GLU ASP PHE GLU MET ALA VAL          
SEQRES  30 C  392  ALA LYS VAL MET GLN LYS ASP SER GLU LYS ASN MET SER          
SEQRES  31 C  392  ILE LYS                                                      
SEQRES   1 D  380  ASP LEU TYR SER ARG TYR LYS LYS LEU GLN GLN GLU LEU          
SEQRES   2 D  380  GLU PHE LEU GLU VAL GLN GLU GLU TYR ILE LYS ASP GLU          
SEQRES   3 D  380  GLN LYS ASN LEU LYS LYS GLU PHE LEU HIS ALA GLN GLU          
SEQRES   4 D  380  GLU VAL LYS ARG ILE GLN SER ILE PRO LEU VAL ILE GLY          
SEQRES   5 D  380  GLN PHE LEU GLU ALA VAL ASP GLN ASN THR ALA ILE VAL          
SEQRES   6 D  380  GLY SER THR THR GLY SER ASN TYR TYR VAL ARG ILE LEU          
SEQRES   7 D  380  SER THR ILE ASP ARG GLU LEU LEU LYS PRO ASN ALA SER          
SEQRES   8 D  380  VAL ALA LEU HIS LYS HIS SER ASN ALA LEU VAL ASP VAL          
SEQRES   9 D  380  LEU PRO PRO GLU ALA ASP SER SER ILE MET MET LEU THR          
SEQRES  10 D  380  SER ASP GLN LYS PRO ASP VAL MET TYR ALA ASP ILE GLY          
SEQRES  11 D  380  GLY MET ASP ILE GLN LYS GLN GLU VAL ARG GLU ALA VAL          
SEQRES  12 D  380  GLU LEU PRO LEU THR HIS PHE GLU LEU TYR LYS GLN ILE          
SEQRES  13 D  380  GLY ILE ASP PRO PRO ARG GLY VAL LEU MET TYR GLY PRO          
SEQRES  14 D  380  PRO GLY CYS GLY LYS THR MET LEU ALA LYS ALA VAL ALA          
SEQRES  15 D  380  HIS HIS THR THR ALA ALA PHE ILE ARG VAL VAL GLY SER          
SEQRES  16 D  380  GLU PHE VAL GLN LYS TYR LEU GLY GLU GLY PRO ARG MET          
SEQRES  17 D  380  VAL ARG ASP VAL PHE ARG LEU ALA LYS GLU ASN ALA PRO          
SEQRES  18 D  380  ALA ILE ILE PHE ILE ASP GLU ILE ASP ALA ILE ALA THR          
SEQRES  19 D  380  LYS ARG PHE ASP ALA GLN THR GLY ALA ASP ARG GLU VAL          
SEQRES  20 D  380  GLN ARG ILE LEU LEU GLU LEU LEU ASN GLN MET ASP GLY          
SEQRES  21 D  380  PHE ASP GLN ASN VAL ASN VAL LYS VAL ILE MET ALA THR          
SEQRES  22 D  380  ASN ARG ALA ASP THR LEU ASP PRO ALA LEU LEU ARG PRO          
SEQRES  23 D  380  GLY ARG LEU ASP ARG LYS ILE GLU PHE PRO LEU PRO ASP          
SEQRES  24 D  380  ARG ARG GLN LYS ARG LEU ILE PHE SER THR ILE THR SER          
SEQRES  25 D  380  LYS MET ASN LEU SER GLU GLU VAL ASP LEU GLU ASP TYR          
SEQRES  26 D  380  VAL ALA ARG PRO ASP LYS ILE SER GLY ALA ASP ILE ASN          
SEQRES  27 D  380  SER ILE CYS GLN GLU SER GLY MET LEU ALA VAL ARG GLU          
SEQRES  28 D  380  ASN ARG TYR ILE VAL LEU ALA LYS ASP PHE GLU LYS ALA          
SEQRES  29 D  380  TYR LYS THR VAL ILE LYS LYS ASP GLU GLN GLU HIS GLU          
SEQRES  30 D  380  PHE TYR LYS                                                  
SEQRES   1 E  375  LYS LEU LEU GLU HIS LYS GLU ILE ASP GLY ARG LEU LYS          
SEQRES   2 E  375  GLU LEU ARG GLU GLN LEU LYS GLU LEU THR LYS GLN TYR          
SEQRES   3 E  375  GLU LYS SER GLU ASN ASP LEU LYS ALA LEU GLN SER VAL          
SEQRES   4 E  375  GLY GLN ILE VAL GLY GLU VAL LEU LYS GLN LEU THR GLU          
SEQRES   5 E  375  GLU LYS PHE ILE VAL LYS ALA THR ASN GLY PRO ARG TYR          
SEQRES   6 E  375  VAL VAL GLY CYS ARG ARG GLN LEU ASP LYS SER LYS LEU          
SEQRES   7 E  375  LYS PRO GLY THR ARG VAL ALA LEU ASP MET THR THR LEU          
SEQRES   8 E  375  THR ILE MET ARG TYR LEU PRO ARG GLU VAL ASP PRO LEU          
SEQRES   9 E  375  VAL TYR ASN MET SER HIS GLU ASP PRO GLY ASN VAL SER          
SEQRES  10 E  375  TYR SER GLU ILE GLY GLY LEU SER GLU GLN ILE ARG GLU          
SEQRES  11 E  375  LEU ARG GLU VAL ILE GLU LEU PRO LEU THR ASN PRO GLU          
SEQRES  12 E  375  LEU PHE GLN ARG VAL GLY ILE ILE PRO PRO LYS GLY CYS          
SEQRES  13 E  375  LEU LEU TYR GLY PRO PRO GLY THR GLY LYS THR LEU LEU          
SEQRES  14 E  375  ALA ARG ALA VAL ALA SER GLN LEU ASP CYS ASN PHE LEU          
SEQRES  15 E  375  LYS VAL VAL SER SER SER ILE VAL ASP LYS TYR ILE GLY          
SEQRES  16 E  375  GLU SER ALA ARG LEU ILE ARG GLU MET PHE ASN TYR ALA          
SEQRES  17 E  375  ARG ASP HIS GLN PRO CYS ILE ILE PHE MET ASP GLU ILE          
SEQRES  18 E  375  ASP ALA ILE GLY GLY ARG ARG PHE SER GLU GLY THR SER          
SEQRES  19 E  375  ALA ASP ARG GLU ILE GLN ARG THR LEU MET GLU LEU LEU          
SEQRES  20 E  375  ASN GLN MET ASP GLY PHE ASP THR LEU HIS ARG VAL LYS          
SEQRES  21 E  375  MET ILE MET ALA THR ASN ARG PRO ASP THR LEU ASP PRO          
SEQRES  22 E  375  ALA LEU LEU ARG PRO GLY ARG LEU ASP ARG LYS ILE HIS          
SEQRES  23 E  375  ILE ASP LEU PRO ASN GLU GLN ALA ARG LEU ASP ILE LEU          
SEQRES  24 E  375  LYS ILE HIS ALA GLY PRO ILE THR LYS HIS GLY GLU ILE          
SEQRES  25 E  375  ASP TYR GLU ALA ILE VAL LYS LEU SER ASP GLY PHE ASN          
SEQRES  26 E  375  GLY ALA ASP LEU ARG ASN VAL CYS THR GLU ALA GLY MET          
SEQRES  27 E  375  PHE ALA ILE ARG ALA ASP HIS ASP PHE VAL VAL GLN GLU          
SEQRES  28 E  375  ASP PHE MET LYS ALA VAL ARG LYS VAL ALA ASP SER LYS          
SEQRES  29 E  375  LYS LEU GLU SER LYS LEU ASP TYR LYS PRO VAL                  
SEQRES   1 F  396  ARG THR ARG LEU LEU ASP SER GLU ILE LYS ILE MET LYS          
SEQRES   2 F  396  SER GLU VAL LEU ARG VAL THR HIS GLU LEU GLN ALA MET          
SEQRES   3 F  396  LYS ASP LYS ILE LYS GLU ASN SER GLU LYS ILE LYS VAL          
SEQRES   4 F  396  ASN LYS THR LEU PRO TYR LEU VAL SER ASN VAL ILE GLU          
SEQRES   5 F  396  LEU LEU ASP VAL ASP PRO ASN ASP GLN GLU GLU ASP GLY          
SEQRES   6 F  396  ALA ASN ILE ASP LEU ASP SER GLN ARG LYS GLY LYS CYS          
SEQRES   7 F  396  ALA VAL ILE LYS THR SER THR ARG GLN THR TYR PHE LEU          
SEQRES   8 F  396  PRO VAL ILE GLY LEU VAL ASP ALA GLU LYS LEU LYS PRO          
SEQRES   9 F  396  GLY ASP LEU VAL GLY VAL ASN LYS ASP SER TYR LEU ILE          
SEQRES  10 F  396  LEU GLU THR LEU PRO THR GLU TYR ASP SER ARG VAL LYS          
SEQRES  11 F  396  ALA MET GLU VAL ASP GLU ARG PRO THR GLU GLN TYR SER          
SEQRES  12 F  396  ASP ILE GLY GLY LEU ASP LYS GLN ILE GLN GLU LEU VAL          
SEQRES  13 F  396  GLU ALA ILE VAL LEU PRO MET ASN HIS LYS GLU LYS PHE          
SEQRES  14 F  396  GLU ASN LEU GLY ILE GLN PRO PRO LYS GLY VAL LEU MET          
SEQRES  15 F  396  TYR GLY PRO PRO GLY THR GLY LYS THR LEU LEU ALA ARG          
SEQRES  16 F  396  ALA CYS ALA ALA GLN THR LYS ALA THR PHE LEU LYS LEU          
SEQRES  17 F  396  ALA GLY PRO GLN LEU VAL GLN MET PHE ILE GLY ASP GLY          
SEQRES  18 F  396  ALA LYS LEU VAL ARG ASP ALA PHE ALA LEU ALA LYS GLU          
SEQRES  19 F  396  LYS ALA PRO SER ILE ILE PHE ILE ASP GLU LEU ASP ALA          
SEQRES  20 F  396  ILE GLY THR LYS ARG PHE ASP SER GLU LYS ALA GLY ASP          
SEQRES  21 F  396  ARG GLU VAL GLN ARG THR MET LEU GLU LEU LEU ASN GLN          
SEQRES  22 F  396  LEU ASP GLY PHE GLN PRO ASN THR GLN VAL LYS VAL ILE          
SEQRES  23 F  396  ALA ALA THR ASN ARG VAL ASP ILE LEU ASP PRO ALA LEU          
SEQRES  24 F  396  LEU ARG SER GLY ARG LEU ASP ARG LYS ILE GLU PHE PRO          
SEQRES  25 F  396  MET PRO ASN GLU GLU ALA ARG ALA ARG ILE MET GLN ILE          
SEQRES  26 F  396  HIS SER ARG LYS MET ASN VAL SER PRO ASP VAL ASN TYR          
SEQRES  27 F  396  GLU GLU LEU ALA ARG CYS THR ASP ASP PHE ASN GLY ALA          
SEQRES  28 F  396  GLN CYS LYS ALA VAL CYS VAL GLU ALA GLY MET ILE ALA          
SEQRES  29 F  396  LEU ARG ARG GLY ALA THR GLU LEU THR HIS GLU ASP TYR          
SEQRES  30 F  396  MET GLU GLY ILE LEU GLU VAL GLN ALA LYS LYS LYS ALA          
SEQRES  31 F  396  ASN LEU GLN TYR TYR ALA                                      
SEQRES   1 f  908  MET GLU GLU GLY GLY ARG ASP LYS ALA PRO VAL GLN PRO          
SEQRES   2 f  908  GLN GLN SER PRO ALA ALA ALA PRO GLY GLY THR ASP GLU          
SEQRES   3 f  908  LYS PRO SER GLY LYS GLU ARG ARG ASP ALA GLY ASP LYS          
SEQRES   4 f  908  ASP LYS GLU GLN GLU LEU SER GLU GLU ASP LYS GLN LEU          
SEQRES   5 f  908  GLN ASP GLU LEU GLU MET LEU VAL GLU ARG LEU GLY GLU          
SEQRES   6 f  908  LYS ASP THR SER LEU TYR ARG PRO ALA LEU GLU GLU LEU          
SEQRES   7 f  908  ARG ARG GLN ILE ARG SER SER THR THR SER MET THR SER          
SEQRES   8 f  908  VAL PRO LYS PRO LEU LYS PHE LEU ARG PRO HIS TYR GLY          
SEQRES   9 f  908  LYS LEU LYS GLU ILE TYR GLU ASN MET ALA PRO GLY GLU          
SEQRES  10 f  908  ASN LYS ARG PHE ALA ALA ASP ILE ILE SER VAL LEU ALA          
SEQRES  11 f  908  MET THR MET SER GLY GLU ARG GLU CYS LEU LYS TYR ARG          
SEQRES  12 f  908  LEU VAL GLY SER GLN GLU GLU LEU ALA SER TRP GLY HIS          
SEQRES  13 f  908  GLU TYR VAL ARG HIS LEU ALA GLY GLU VAL ALA LYS GLU          
SEQRES  14 f  908  TRP GLN GLU LEU ASP ASP ALA GLU LYS VAL GLN ARG GLU          
SEQRES  15 f  908  PRO LEU LEU THR LEU VAL LYS GLU ILE VAL PRO TYR ASN          
SEQRES  16 f  908  MET ALA HIS ASN ALA GLU HIS GLU ALA CYS ASP LEU LEU          
SEQRES  17 f  908  MET GLU ILE GLU GLN VAL ASP MET LEU GLU LYS ASP ILE          
SEQRES  18 f  908  ASP GLU ASN ALA TYR ALA LYS VAL CYS LEU TYR LEU THR          
SEQRES  19 f  908  SER CYS VAL ASN TYR VAL PRO GLU PRO GLU ASN SER ALA          
SEQRES  20 f  908  LEU LEU ARG CYS ALA LEU GLY VAL PHE ARG LYS PHE SER          
SEQRES  21 f  908  ARG PHE PRO GLU ALA LEU ARG LEU ALA LEU MET LEU ASN          
SEQRES  22 f  908  ASP MET GLU LEU VAL GLU ASP ILE PHE THR SER CYS LYS          
SEQRES  23 f  908  ASP VAL VAL VAL GLN LYS GLN MET ALA PHE MET LEU GLY          
SEQRES  24 f  908  ARG HIS GLY VAL PHE LEU GLU LEU SER GLU ASP VAL GLU          
SEQRES  25 f  908  GLU TYR GLU ASP LEU THR GLU ILE MET SER ASN VAL GLN          
SEQRES  26 f  908  LEU ASN SER ASN PHE LEU ALA LEU ALA ARG GLU LEU ASP          
SEQRES  27 f  908  ILE MET GLU PRO LYS VAL PRO ASP ASP ILE TYR LYS THR          
SEQRES  28 f  908  HIS LEU GLU ASN ASN ARG PHE GLY GLY SER GLY SER GLN          
SEQRES  29 f  908  VAL ASP SER ALA ARG MET ASN LEU ALA SER SER PHE VAL          
SEQRES  30 f  908  ASN GLY PHE VAL ASN ALA ALA PHE GLY GLN ASP LYS LEU          
SEQRES  31 f  908  LEU THR ASP ASP GLY ASN LYS TRP LEU TYR LYS ASN LYS          
SEQRES  32 f  908  ASP HIS GLY MET LEU SER ALA ALA ALA SER LEU GLY MET          
SEQRES  33 f  908  ILE LEU LEU TRP ASP VAL ASP GLY GLY LEU THR GLN ILE          
SEQRES  34 f  908  ASP LYS TYR LEU TYR SER SER GLU ASP TYR ILE LYS SER          
SEQRES  35 f  908  GLY ALA LEU LEU ALA CYS GLY ILE VAL ASN SER GLY VAL          
SEQRES  36 f  908  ARG ASN GLU CYS ASP PRO ALA LEU ALA LEU LEU SER ASP          
SEQRES  37 f  908  TYR VAL LEU HIS ASN SER ASN THR MET ARG LEU GLY SER          
SEQRES  38 f  908  ILE PHE GLY LEU GLY LEU ALA TYR ALA GLY SER ASN ARG          
SEQRES  39 f  908  GLU ASP VAL LEU THR LEU LEU LEU PRO VAL MET GLY ASP          
SEQRES  40 f  908  SER LYS SER SER MET GLU VAL ALA GLY VAL THR ALA LEU          
SEQRES  41 f  908  ALA CYS GLY MET ILE ALA VAL GLY SER CYS ASN GLY ASP          
SEQRES  42 f  908  VAL THR SER THR ILE LEU GLN THR ILE MET GLU LYS SER          
SEQRES  43 f  908  GLU THR GLU LEU LYS ASP THR TYR ALA ARG TRP LEU PRO          
SEQRES  44 f  908  LEU GLY LEU GLY LEU ASN HIS LEU GLY LYS GLY GLU ALA          
SEQRES  45 f  908  ILE GLU ALA ILE LEU ALA ALA LEU GLU VAL VAL SER GLU          
SEQRES  46 f  908  PRO PHE ARG SER PHE ALA ASN THR LEU VAL ASP VAL CYS          
SEQRES  47 f  908  ALA TYR ALA GLY SER GLY ASN VAL LEU LYS VAL GLN GLN          
SEQRES  48 f  908  LEU LEU HIS ILE CYS SER GLU HIS PHE ASP SER LYS GLU          
SEQRES  49 f  908  LYS GLU GLU ASP LYS ASP LYS LYS GLU LYS LYS ASP LYS          
SEQRES  50 f  908  ASP LYS LYS GLU ALA PRO ALA ASP MET GLY ALA HIS GLN          
SEQRES  51 f  908  GLY VAL ALA VAL LEU GLY ILE ALA LEU ILE ALA MET GLY          
SEQRES  52 f  908  GLU GLU ILE GLY ALA GLU MET ALA LEU ARG THR PHE GLY          
SEQRES  53 f  908  HIS LEU LEU ARG TYR GLY GLU PRO THR LEU ARG ARG ALA          
SEQRES  54 f  908  VAL PRO LEU ALA LEU ALA LEU ILE SER VAL SER ASN PRO          
SEQRES  55 f  908  ARG LEU ASN ILE LEU ASP THR LEU SER LYS PHE SER HIS          
SEQRES  56 f  908  ASP ALA ASP PRO GLU VAL SER TYR ASN SER ILE PHE ALA          
SEQRES  57 f  908  MET GLY MET VAL GLY SER GLY THR ASN ASN ALA ARG LEU          
SEQRES  58 f  908  ALA ALA MET LEU ARG GLN LEU ALA GLN TYR HIS ALA LYS          
SEQRES  59 f  908  ASP PRO ASN ASN LEU PHE MET VAL ARG LEU ALA GLN GLY          
SEQRES  60 f  908  LEU THR HIS LEU GLY LYS GLY THR LEU THR LEU CYS PRO          
SEQRES  61 f  908  TYR HIS SER ASP ARG GLN LEU MET SER GLN VAL ALA VAL          
SEQRES  62 f  908  ALA GLY LEU LEU THR VAL LEU VAL SER PHE LEU ASP VAL          
SEQRES  63 f  908  ARG ASN ILE ILE LEU GLY LYS SER HIS TYR VAL LEU TYR          
SEQRES  64 f  908  GLY LEU VAL ALA ALA MET GLN PRO ARG MET LEU VAL THR          
SEQRES  65 f  908  PHE ASP GLU GLU LEU ARG PRO LEU PRO VAL SER VAL ARG          
SEQRES  66 f  908  VAL GLY GLN ALA VAL ASP VAL VAL GLY GLN ALA GLY LYS          
SEQRES  67 f  908  PRO LYS THR ILE THR GLY PHE GLN THR HIS THR THR PRO          
SEQRES  68 f  908  VAL LEU LEU ALA HIS GLY GLU ARG ALA GLU LEU ALA THR          
SEQRES  69 f  908  GLU GLU PHE LEU PRO VAL THR PRO ILE LEU GLU GLY PHE          
SEQRES  70 f  908  VAL ILE LEU ARG LYS ASN PRO ASN TYR ASP LEU                  
HET     ZN  c 401       1                                                       
HET    AGS  A 501      31                                                       
HET    AGS  B 501      31                                                       
HET    AGS  D 501      31                                                       
HET    AGS  F 501      31                                                       
HETNAM      ZN ZINC ION                                                         
HETNAM     AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER                       
HETSYN     AGS ATP-GAMMA-S; ADENOSINE 5'-(3-THIOTRIPHOSPHATE);                  
HETSYN   2 AGS  ADENOSINE 5'-(GAMMA-THIOTRIPHOSPHATE); ADENOSINE-5'-            
HETSYN   3 AGS  DIPHOSPHATE MONOTHIOPHOSPHATE                                   
FORMUL  47   ZN    ZN 2+                                                        
FORMUL  48  AGS    4(C10 H16 N5 O12 P3 S)                                       
HELIX    1 AA1 GLU U   16  VAL U   31  1                                  16    
HELIX    2 AA2 PHE U   34  SER U   39  1                                   6    
HELIX    3 AA3 SER U   41  ASP U   51  1                                  11    
HELIX    4 AA4 SER U   56  GLY U   72  1                                  17    
HELIX    5 AA5 PHE U   74  GLY U   83  1                                  10    
HELIX    6 AA6 GLU U   95  ASP U  117  1                                  23    
HELIX    7 AA7 GLU U  131  ASP U  144  1                                  14    
HELIX    8 AA8 TYR U  147  ARG U  158  1                                  12    
HELIX    9 AA9 ASP U  161  THR U  166  1                                   6    
HELIX   10 AB1 PRO U  174  LEU U  187  1                                  14    
HELIX   11 AB2 PHE U  193  MET U  206  1                                  14    
HELIX   12 AB3 PHE U  213  LEU U  223  1                                  11    
HELIX   13 AB4 GLN U  227  GLU U  239  1                                  13    
HELIX   14 AB5 ALA U  245  SER U  255  1                                  11    
HELIX   15 AB6 SER U  257  ARG U  269  1                                  13    
HELIX   16 AB7 GLN U  321  GLY U  331  1                                  11    
HELIX   17 AB8 GLY U  331  ASN U  345  1                                  15    
HELIX   18 AB9 ASP U  349  ASP U  358  1                                  10    
HELIX   19 AC1 SER U  363  MET U  376  1                                  14    
HELIX   20 AC2 ASN U  398  ILE U  411  1                                  14    
HELIX   21 AC3 GLU U  418  MET U  423  1                                   6    
HELIX   22 AC4 ALA U  436  HIS U  450  1                                  15    
HELIX   23 AC5 ASP U  456  LYS U  466  1                                  11    
HELIX   24 AC6 VAL U  473  ALA U  485  1                                  13    
HELIX   25 AC7 GLN U  491  TYR U  502  1                                  12    
HELIX   26 AC8 ASP U  505  MET U  520  1                                  16    
HELIX   27 AC9 GLN U  527  THR U  539  1                                  13    
HELIX   28 AD1 GLU U  542  VAL U  555  1                                  14    
HELIX   29 AD2 ALA U  563  ASP U  573  1                                  11    
HELIX   30 AD3 ASP U  575  TYR U  590  1                                  16    
HELIX   31 AD4 ALA U  598  SER U  608  1                                  11    
HELIX   32 AD5 ASN U  611  LEU U  626  1                                  16    
HELIX   33 AD6 GLU U  631  SER U  641  1                                  11    
HELIX   34 AD7 ASN U  645  CYS U  660  1                                  16    
HELIX   35 AD8 LYS U  666  THR U  676  1                                  11    
HELIX   36 AD9 VAL U  680  MET U  695  1                                  16    
HELIX   37 AE1 LYS U  705  ASP U  719  1                                  15    
HELIX   38 AE2 GLY U  729  ASP U  738  1                                  10    
HELIX   39 AE3 HIS U  756  THR U  767  1                                  12    
HELIX   40 AE4 PHE U  773  PHE U  778  1                                   6    
HELIX   41 AE5 ALA U  887  LYS U  890  5                                   4    
HELIX   42 AE6 PRO V   29  GLY V   53  1                                  25    
HELIX   43 AE7 ALA V   60  LYS V   76  1                                  17    
HELIX   44 AE8 GLY V   88  VAL V   94  1                                   7    
HELIX   45 AE9 THR V  104  TYR V  114  1                                  11    
HELIX   46 AF1 LYS V  115  PHE V  120  1                                   6    
HELIX   47 AF2 PHE V  130  LEU V  135  1                                   6    
HELIX   48 AF3 GLU V  136  THR V  141  1                                   6    
HELIX   49 AF4 PHE V  147  THR V  157  1                                  11    
HELIX   50 AF5 LEU V  159  GLU V  164  1                                   6    
HELIX   51 AF6 VAL V  171  LEU V  191  1                                  21    
HELIX   52 AF7 ASN V  199  GLU V  219  1                                  21    
HELIX   53 AF8 VAL V  226  ALA V  238  1                                  13    
HELIX   54 AF9 GLY V  246  TYR V  261  1                                  16    
HELIX   55 AG1 GLN V  266  SER V  272  1                                   7    
HELIX   56 AG2 ASN V  283  LEU V  300  1                                  18    
HELIX   57 AG3 TYR V  302  LYS V  315  1                                  14    
HELIX   58 AG4 GLY V  323  ILE V  333  1                                  11    
HELIX   59 AG5 ILE V  333  LEU V  338  1                                   6    
HELIX   60 AG6 ARG V  345  ARG V  349  5                                   5    
HELIX   61 AG7 PRO V  359  THR V  369  1                                  11    
HELIX   62 AG8 ASN V  371  GLY V  390  1                                  20    
HELIX   63 AG9 TYR V  392  TYR V  414  1                                  23    
HELIX   64 AH1 SER V  418  GLN V  424  1                                   7    
HELIX   65 AH2 SER V  430  ASP V  444  1                                  15    
HELIX   66 AH3 THR V  469  ARG V  495  1                                  27    
HELIX   67 AH4 ALA W    2  ILE W   13  1                                  12    
HELIX   68 AH5 VAL W   14  GLU W   17  5                                   4    
HELIX   69 AH6 SER W   21  GLN W   26  1                                   6    
HELIX   70 AH7 ARG W   27  GLY W   38  1                                  12    
HELIX   71 AH8 GLU W   42  SER W   64  1                                  23    
HELIX   72 AH9 ALA W   69  GLU W   85  1                                  17    
HELIX   73 AI1 ARG W   94  ILE W  115  1                                  22    
HELIX   74 AI2 THR W  116  GLY W  134  1                                  19    
HELIX   75 AI3 VAL W  138  ASN W  156  1                                  19    
HELIX   76 AI4 ASP W  158  GLU W  168  1                                  11    
HELIX   77 AI5 LYS W  180  LEU W  187  1                                   8    
HELIX   78 AI6 ASP W  198  ASN W  210  1                                  13    
HELIX   79 AI7 LYS W  221  LEU W  233  1                                  13    
HELIX   80 AI8 LYS W  245  ILE W  250  1                                   6    
HELIX   81 AI9 GLU W  261  LEU W  272  1                                  12    
HELIX   82 AJ1 GLU W  282  ILE W  290  1                                   9    
HELIX   83 AJ2 ILE W  299  LEU W  308  1                                  10    
HELIX   84 AJ3 ARG W  316  MET W  326  1                                  11    
HELIX   85 AJ4 GLU W  334  PHE W  341  1                                   8    
HELIX   86 AJ5 GLU W  346  ALA W  367  1                                  22    
HELIX   87 AJ6 MET W  375  LEU W  382  1                                   8    
HELIX   88 AJ7 VAL W  386  LYS W  400  1                                  15    
HELIX   89 AJ8 LEU W  424  ASN W  454  1                                  31    
HELIX   90 AJ9 LEU X  183  ALA X  197  1                                  15    
HELIX   91 AK1 LYS X  205  ILE X  217  1                                  13    
HELIX   92 AK2 ASP X  224  GLU X  237  1                                  14    
HELIX   93 AK3 ASP X  243  ILE X  248  1                                   6    
HELIX   94 AK4 LEU X  251  ASN X  262  1                                  12    
HELIX   95 AK5 ASP X  266  VAL X  271  1                                   6    
HELIX   96 AK6 GLY X  281  ARG X  297  1                                  17    
HELIX   97 AK7 SER X  298  GLU X  303  1                                   6    
HELIX   98 AK8 LYS X  304  TYR X  309  1                                   6    
HELIX   99 AK9 SER X  320  ILE X  339  1                                  20    
HELIX  100 AL1 ILE X  347  SER X  351  1                                   5    
HELIX  101 AL2 ASP X  360  ASP X  371  1                                  12    
HELIX  102 AL3 VAL X  393  THR X  422  1                                  30    
HELIX  103 AL4 LYS Y   13  LEU Y   28  1                                  16    
HELIX  104 AL5 ASP Y   34  ARG Y   46  1                                  13    
HELIX  105 AL6 MET Y   50  LYS Y   59  1                                  10    
HELIX  106 AL7 VAL Y   67  GLU Y   92  1                                  26    
HELIX  107 AL8 SER Y   98  GLY Y  115  1                                  18    
HELIX  108 AL9 ASP Y  116  PHE Y  124  1                                   9    
HELIX  109 AM1 LEU Y  134  TYR Y  151  1                                  18    
HELIX  110 AM2 ASN Y  154  LEU Y  167  1                                  14    
HELIX  111 AM3 ASP Y  175  ILE Y  191  1                                  17    
HELIX  112 AM4 ASP Y  193  PHE Y  201  1                                   9    
HELIX  113 AM5 ASP Y  215  LEU Y  231  1                                  17    
HELIX  114 AM6 GLU Y  232  ILE Y  241  1                                  10    
HELIX  115 AM7 LEU Y  253  TYR Y  264  1                                  12    
HELIX  116 AM8 TYR Y  268  LYS Y  284  1                                  17    
HELIX  117 AM9 HIS Y  291  TYR Y  311  1                                  21    
HELIX  118 AN1 MET Y  319  GLY Y  324  1                                   6    
HELIX  119 AN2 GLU Y  328  ALA Y  340  1                                  13    
HELIX  120 AN3 ASN Y  363  SER Y  384  1                                  22    
HELIX  121 AN4 PRO Z   13  GLY Z   30  1                                  18    
HELIX  122 AN5 LEU Z   75  ASN Z   86  1                                  12    
HELIX  123 AN6 ASN Z  104  LYS Z  113  1                                  10    
HELIX  124 AN7 ARG Z  114  CYS Z  116  5                                   3    
HELIX  125 AN8 GLU Z  168  GLU Z  173  1                                   6    
HELIX  126 AN9 LEU Z  187  THR Z  217  1                                  31    
HELIX  127 AO1 LEU Z  220  HIS Z  224  5                                   5    
HELIX  128 AO2 ILE Z  227  ASN Z  235  1                                   9    
HELIX  129 AO3 PHE Z  245  GLU Z  289  1                                  45    
HELIX  130 AO4 PRO a    5  SER a   11  1                                   7    
HELIX  131 AO5 GLN a   18  TYR a   29  1                                  12    
HELIX  132 AO6 TRP a   34  ASP a   47  1                                  14    
HELIX  133 AO7 GLY a   53  GLU a   68  1                                  16    
HELIX  134 AO8 PRO a   73  THR a   88  1                                  16    
HELIX  135 AO9 ASP a   89  VAL a  104  1                                  16    
HELIX  136 AP1 ALA a  110  LEU a  121  1                                  12    
HELIX  137 AP2 LYS a  122  ILE a  125  5                                   4    
HELIX  138 AP3 VAL a  130  MET a  141  1                                  12    
HELIX  139 AP4 SER a  150  TYR a  162  1                                  13    
HELIX  140 AP5 ALA a  170  GLY a  181  1                                  12    
HELIX  141 AP6 PRO a  189  LEU a  206  1                                  18    
HELIX  142 AP7 GLU a  215  MET a  218  5                                   4    
HELIX  143 AP8 HIS a  219  ASN a  227  1                                   9    
HELIX  144 AP9 TRP a  232  PHE a  240  1                                   9    
HELIX  145 AQ1 GLU a  246  GLY a  256  1                                  11    
HELIX  146 AQ2 ASN a  264  THR a  283  1                                  20    
HELIX  147 AQ3 PHE a  293  ALA a  300  1                                   8    
HELIX  148 AQ4 THR a  303  ASN a  305  5                                   3    
HELIX  149 AQ5 GLU a  306  GLY a  318  1                                  13    
HELIX  150 AQ6 ASP a  342  GLY a  348  1                                   7    
HELIX  151 AQ7 MET a  349  ALA a  371  1                                  23    
HELIX  152 AQ8 HIS a  372  LEU a  375  5                                   4    
HELIX  153 AQ9 ARG b   25  ASN b   44  1                                  20    
HELIX  154 AR1 THR b   68  LEU b   75  1                                   8    
HELIX  155 AR2 THR b   85  LEU b   97  1                                  13    
HELIX  156 AR3 ASN b  120  GLU b  134  1                                  15    
HELIX  157 AR4 GLU b  151  LEU b  160  1                                  10    
HELIX  158 AR5 LEU b  179  LEU b  183  5                                   5    
HELIX  159 AR6 ILE b  184  ALA b  190  1                                   7    
HELIX  160 AR7 SER c   34  ALA c   47  1                                  14    
HELIX  161 AR8 SER c   83  VAL c   87  5                                   5    
HELIX  162 AR9 ASP c   88  GLN c  101  1                                  14    
HELIX  163 AS1 VAL c  125  ALA c  135  1                                  11    
HELIX  164 AS2 ASN c  164  VAL c  169  5                                   6    
HELIX  165 AS3 SER c  179  ASN c  185  1                                   7    
HELIX  166 AS4 GLN c  190  LEU c  196  1                                   7    
HELIX  167 AS5 ASN c  210  TRP c  225  1                                  16    
HELIX  168 AS6 LYS c  246  VAL c  259  1                                  14    
HELIX  169 AS7 VAL c  259  LYS c  264  1                                   6    
HELIX  170 AS8 VAL c  288  PHE c  309  1                                  22    
HELIX  171 AS9 TYR d    2  GLY d    7  5                                   6    
HELIX  172 AT1 SER d   17  LEU d   33  1                                  17    
HELIX  173 AT2 LYS d   45  ARG d   65  1                                  21    
HELIX  174 AT3 ASP d   67  TYR d   82  1                                  16    
HELIX  175 AT4 TYR d   94  GLN d  109  1                                  16    
HELIX  176 AT5 ALA d  113  LEU d  122  1                                  10    
HELIX  177 AT6 ASN d  130  MET d  144  1                                  15    
HELIX  178 AT7 ASN d  149  GLY d  156  1                                   8    
HELIX  179 AT8 TYR d  163  CYS d  181  1                                  19    
HELIX  180 AT9 LEU d  190  LEU d  198  1                                   9    
HELIX  181 AU1 PRO d  203  LYS d  211  1                                   9    
HELIX  182 AU2 SER d  239  GLU d  254  1                                  16    
HELIX  183 AU3 ASP e   44  ASP e   50  1                                   7    
HELIX  184 AU4 GLU e   61  LYS e   66  1                                   6    
HELIX  185 AU5 GLN G   24  PHE G   29  1                                   6    
HELIX  186 AU6 SER G   63  THR G   67  5                                   5    
HELIX  187 AU7 MET G   83  GLY G  106  1                                  24    
HELIX  188 AU8 PRO G  110  ASN G  128  1                                  19    
HELIX  189 AU9 LYS G  171  LYS G  181  1                                  11    
HELIX  190 AV1 PHE G  191  LEU G  206  1                                  16    
HELIX  191 AV2 THR G  231  LEU G  242  1                                  12    
HELIX  192 AV3 LEU H   19  GLY H   31  1                                  13    
HELIX  193 AV4 MET H   79  GLN H  102  1                                  24    
HELIX  194 AV5 PRO H  106  GLN H  123  1                                  18    
HELIX  195 AV6 ASN H  166  TYR H  178  1                                  13    
HELIX  196 AV7 GLU H  183  PHE H  199  1                                  17    
HELIX  197 AV8 THR H  222  LEU H  230  1                                   9    
HELIX  198 AV9 TYR I   19  GLY I   29  1                                  11    
HELIX  199 AW1 SER I   81  GLN I  102  1                                  22    
HELIX  200 AW2 CYS I  107  PHE I  124  1                                  18    
HELIX  201 AW3 SER I  168  ASP I  178  1                                  11    
HELIX  202 AW4 THR I  185  MET I  201  1                                  17    
HELIX  203 AW5 SER I  207  GLU I  209  5                                   3    
HELIX  204 AW6 GLN I  230  GLU I  248  1                                  19    
HELIX  205 AW7 ARG I  249  LYS I  251  5                                   3    
HELIX  206 AW8 LEU J   16  LYS J   28  1                                  13    
HELIX  207 AW9 LEU J   76  VAL J   98  1                                  23    
HELIX  208 AX1 THR J  103  SER J  121  1                                  19    
HELIX  209 AX2 PHE J  138  GLY J  140  5                                   3    
HELIX  210 AX3 GLY J  164  LYS J  174  1                                  11    
HELIX  211 AX4 THR J  183  GLU J  197  1                                  15    
HELIX  212 AX5 GLU J  223  ASN J  239  1                                  17    
HELIX  213 AX6 GLN K   23  LEU K   33  1                                  11    
HELIX  214 AX7 GLU K   60  ILE K   64  5                                   5    
HELIX  215 AX8 LEU K   81  ASN K  104  1                                  24    
HELIX  216 AX9 THR K  108  ASN K  118  1                                  11    
HELIX  217 AY1 ALA K  173  TYR K  185  1                                  13    
HELIX  218 AY2 THR K  190  MET K  206  1                                  17    
HELIX  219 AY3 GLU K  233  LYS K  239  1                                   7    
HELIX  220 AY4 ILE L   19  LYS L   30  1                                  12    
HELIX  221 AY5 THR L   78  PHE L   99  1                                  22    
HELIX  222 AY6 PRO L  104  ILE L  118  1                                  15    
HELIX  223 AY7 PRO L  119  GLN L  121  5                                   3    
HELIX  224 AY8 SER L  165  ARG L  174  1                                  10    
HELIX  225 AY9 GLU L  178  CYS L  182  5                                   5    
HELIX  226 AZ1 ASN L  183  ARG L  196  1                                  14    
HELIX  227 AZ2 VAL L  229  GLU L  234  1                                   6    
HELIX  228 AZ3 VAL M   20  LYS M   28  1                                   9    
HELIX  229 AZ4 ALA M   29  SER M   33  5                                   5    
HELIX  230 AZ5 LEU M   80  GLY M  103  1                                  24    
HELIX  231 AZ6 PRO M  107  TYR M  125  1                                  19    
HELIX  232 AZ7 ALA M  168  GLU M  177  1                                  10    
HELIX  233 AZ8 THR M  185  VAL M  200  1                                  16    
HELIX  234 AZ9 ALA M  235  LYS M  240  1                                   6    
HELIX  235 BA1 SER N   48  ASN N   71  1                                  24    
HELIX  236 BA2 LEU N   75  TYR N   90  1                                  16    
HELIX  237 BA3 GLY N  129  SER N  133  5                                   5    
HELIX  238 BA4 TYR N  134  TYR N  143  1                                  10    
HELIX  239 BA5 THR N  148  ASP N  167  1                                  20    
HELIX  240 BA6 THR O   48  GLY O   71  1                                  24    
HELIX  241 BA7 ARG O   75  TYR O   90  1                                  16    
HELIX  242 BA8 GLY O  130  PHE O  142  1                                  13    
HELIX  243 BA9 GLU O  147  ASN O  165  1                                  19    
HELIX  244 BB1 LEU P   56  GLU P   78  1                                  23    
HELIX  245 BB2 LYS P   83  GLU P   97  1                                  15    
HELIX  246 BB3 ALA P  143  TRP P  154  1                                  12    
HELIX  247 BB4 ASP P  159  ASP P  178  1                                  20    
HELIX  248 BB5 GLY Q   51  ASN Q   71  1                                  21    
HELIX  249 BB6 SER Q   76  ARG Q   93  1                                  18    
HELIX  250 BB7 TYR Q  134  TYR Q  146  1                                  13    
HELIX  251 BB8 SER Q  152  GLN Q  168  1                                  17    
HELIX  252 BB9 ALA R   49  LYS R   71  1                                  23    
HELIX  253 BC1 SER R   75  GLN R   89  1                                  15    
HELIX  254 BC2 GLY R  131  TYR R  143  1                                  13    
HELIX  255 BC3 GLU R  148  ASP R  167  1                                  20    
HELIX  256 BC4 ASN R  191  SER R  200  1                                  10    
HELIX  257 BC5 PHE S   57  ASN S   80  1                                  24    
HELIX  258 BC6 THR S   84  ARG S   99  1                                  16    
HELIX  259 BC7 LEU S  145  VAL S  153  1                                   9    
HELIX  260 BC8 SER S  167  ASP S  186  1                                  20    
HELIX  261 BC9 ASP T   56  GLY T   78  1                                  23    
HELIX  262 BD1 SER T   84  LYS T  102  1                                  19    
HELIX  263 BD2 TYR T  141  ALA T  146  1                                   6    
HELIX  264 BD3 ALA T  146  GLN T  157  1                                  12    
HELIX  265 BD4 SER T  161  ASP T  180  1                                  20    
HELIX  266 BD5 SER g   17  ARG g   21  5                                   5    
HELIX  267 BD6 GLN g   24  PHE g   29  1                                   6    
HELIX  268 BD7 MET g   83  GLY g  106  1                                  24    
HELIX  269 BD8 PRO g  110  ASN g  128  1                                  19    
HELIX  270 BD9 LYS g  171  VAL g  183  1                                  13    
HELIX  271 BE1 PHE g  191  LEU g  206  1                                  16    
HELIX  272 BE2 THR g  231  LEU g  242  1                                  12    
HELIX  273 BE3 LEU h   19  GLY h   31  1                                  13    
HELIX  274 BE4 MET h   79  GLN h  102  1                                  24    
HELIX  275 BE5 PRO h  106  SER h  124  1                                  19    
HELIX  276 BE6 ASN h  166  TYR h  178  1                                  13    
HELIX  277 BE7 GLU h  183  PHE h  199  1                                  17    
HELIX  278 BE8 THR h  222  LEU h  230  1                                   9    
HELIX  279 BE9 TYR i   19  GLY i   29  1                                  11    
HELIX  280 BF1 ILE i   79  GLN i  102  1                                  24    
HELIX  281 BF2 CYS i  107  PHE i  124  1                                  18    
HELIX  282 BF3 SER i  168  ASP i  178  1                                  11    
HELIX  283 BF4 THR i  185  MET i  201  1                                  17    
HELIX  284 BF5 SER i  207  GLU i  209  5                                   3    
HELIX  285 BF6 GLN i  230  GLU i  248  1                                  19    
HELIX  286 BF7 ARG i  249  LYS i  251  5                                   3    
HELIX  287 BF8 GLN j   18  LYS j   28  1                                  11    
HELIX  288 BF9 LEU j   76  VAL j   98  1                                  23    
HELIX  289 BG1 THR j  103  SER j  121  1                                  19    
HELIX  290 BG2 PHE j  138  GLY j  140  5                                   3    
HELIX  291 BG3 GLY j  164  LYS j  174  1                                  11    
HELIX  292 BG4 THR j  183  GLU j  197  1                                  15    
HELIX  293 BG5 GLU j  223  ASN j  239  1                                  17    
HELIX  294 BG6 LEU k   21  LYS k   32  1                                  12    
HELIX  295 BG7 GLU k   60  ILE k   64  5                                   5    
HELIX  296 BG8 ILE k   82  ASN k  104  1                                  23    
HELIX  297 BG9 THR k  108  ASN k  118  1                                  11    
HELIX  298 BH1 ALA k  173  TYR k  185  1                                  13    
HELIX  299 BH2 THR k  190  MET k  206  1                                  17    
HELIX  300 BH3 GLU k  233  LYS k  239  1                                   7    
HELIX  301 BH4 ILE l   19  LYS l   30  1                                  12    
HELIX  302 BH5 THR l   78  PHE l   99  1                                  22    
HELIX  303 BH6 PRO l  104  ILE l  118  1                                  15    
HELIX  304 BH7 PRO l  119  GLN l  121  5                                   3    
HELIX  305 BH8 SER l  165  ARG l  174  1                                  10    
HELIX  306 BH9 HIS l  175  MET l  180  1                                   6    
HELIX  307 BI1 ASN l  183  ARG l  196  1                                  14    
HELIX  308 BI2 VAL l  229  GLU l  234  1                                   6    
HELIX  309 BI3 VAL m   20  LYS m   28  1                                   9    
HELIX  310 BI4 ALA m   29  SER m   33  5                                   5    
HELIX  311 BI5 LEU m   80  GLY m  103  1                                  24    
HELIX  312 BI6 PRO m  107  TYR m  125  1                                  19    
HELIX  313 BI7 ALA m  168  GLU m  177  1                                  10    
HELIX  314 BI8 THR m  185  VAL m  200  1                                  16    
HELIX  315 BI9 ALA m  235  LYS m  240  1                                   6    
HELIX  316 BJ1 SER n   48  ASN n   71  1                                  24    
HELIX  317 BJ2 LEU n   75  TYR n   90  1                                  16    
HELIX  318 BJ3 GLY n  129  SER n  133  5                                   5    
HELIX  319 BJ4 TYR n  134  TYR n  143  1                                  10    
HELIX  320 BJ5 THR n  148  ASP n  167  1                                  20    
HELIX  321 BJ6 THR o   48  GLY o   71  1                                  24    
HELIX  322 BJ7 ARG o   75  TYR o   90  1                                  16    
HELIX  323 BJ8 GLY o  130  PHE o  142  1                                  13    
HELIX  324 BJ9 GLU o  147  ASN o  165  1                                  19    
HELIX  325 BK1 LEU p   56  GLU p   78  1                                  23    
HELIX  326 BK2 LYS p   83  GLU p   97  1                                  15    
HELIX  327 BK3 ALA p  143  TRP p  154  1                                  12    
HELIX  328 BK4 ASP p  159  ASP p  178  1                                  20    
HELIX  329 BK5 GLY q   51  ASN q   71  1                                  21    
HELIX  330 BK6 SER q   76  ARG q   93  1                                  18    
HELIX  331 BK7 TYR q  134  TYR q  146  1                                  13    
HELIX  332 BK8 SER q  152  GLN q  168  1                                  17    
HELIX  333 BK9 ALA r   49  LYS r   71  1                                  23    
HELIX  334 BL1 SER r   75  GLN r   89  1                                  15    
HELIX  335 BL2 GLY r  131  TYR r  143  1                                  13    
HELIX  336 BL3 GLU r  148  ASP r  167  1                                  20    
HELIX  337 BL4 ASN r  191  SER r  200  1                                  10    
HELIX  338 BL5 PHE s   57  ASN s   80  1                                  24    
HELIX  339 BL6 THR s   84  ARG s   99  1                                  16    
HELIX  340 BL7 LEU s  145  VAL s  153  1                                   9    
HELIX  341 BL8 SER s  167  ASP s  186  1                                  20    
HELIX  342 BL9 ASP t   56  LEU t   76  1                                  21    
HELIX  343 BM1 SER t   84  LYS t  102  1                                  19    
HELIX  344 BM2 TYR t  141  ALA t  146  1                                   6    
HELIX  345 BM3 ALA t  146  GLN t  157  1                                  12    
HELIX  346 BM4 SER t  161  ASP t  180  1                                  20    
HELIX  347 BM5 ASP A   83  GLN A   88  1                                   6    
HELIX  348 BM6 CYS A  180  HIS A  197  1                                  18    
HELIX  349 BM7 GLY A  221  VAL A  229  1                                   9    
HELIX  350 BM8 ALA A  230  ARG A  232  5                                   3    
HELIX  351 BM9 ILE A  241  VAL A  246  5                                   6    
HELIX  352 BN1 GLY A  251  ARG A  265  1                                  15    
HELIX  353 BN2 ASN A  293  ASP A  307  1                                  15    
HELIX  354 BN3 LEU A  348  SER A  361  1                                  14    
HELIX  355 BN4 PHE A  370  LEU A  376  1                                   7    
HELIX  356 BN5 THR A  381  ALA A  399  1                                  19    
HELIX  357 BN6 THR A  405  SER A  419  1                                  15    
HELIX  358 BN7 GLN B   92  ARG B  103  1                                  12    
HELIX  359 BN8 ASP B  140  LEU B  144  5                                   5    
HELIX  360 BN9 LEU B  170  LYS B  175  1                                   6    
HELIX  361 BO1 ASN B  192  HIS B  207  1                                  16    
HELIX  362 BO2 TYR B  210  GLY B  215  1                                   6    
HELIX  363 BO3 GLY B  231  GLN B  242  1                                  12    
HELIX  364 BO4 SER B  253  ILE B  256  5                                   4    
HELIX  365 BO5 GLY B  261  GLU B  276  1                                  16    
HELIX  366 BO6 GLY B  300  ARG B  303  5                                   4    
HELIX  367 BO7 GLU B  304  ASP B  317  1                                  14    
HELIX  368 BO8 ASP B  338  ARG B  343  1                                   6    
HELIX  369 BO9 ASP B  357  THR B  369  1                                  13    
HELIX  370 BP1 LEU B  380  LYS B  387  1                                   8    
HELIX  371 BP2 SER B  391  GLU B  409  1                                  19    
HELIX  372 BP3 THR B  415  LEU B  427  1                                  13    
HELIX  373 BP4 ILE C   28  ASN C   36  1                                   9    
HELIX  374 BP5 LYS C   38  GLU C   61  1                                  24    
HELIX  375 BP6 GLU C   62  GLU C   68  5                                   7    
HELIX  376 BP7 PRO C  133  MET C  139  1                                   7    
HELIX  377 BP8 THR C  147  ILE C  151  5                                   5    
HELIX  378 BP9 LEU C  154  ILE C  165  1                                  12    
HELIX  379 BQ1 ILE C  165  HIS C  171  1                                   7    
HELIX  380 BQ2 PRO C  172  PHE C  175  5                                   4    
HELIX  381 BQ3 GLY C  195  ALA C  204  1                                  10    
HELIX  382 BQ4 ARG C  232  HIS C  241  1                                  10    
HELIX  383 BQ5 GLU C  268  LEU C  280  1                                  13    
HELIX  384 BQ6 ASP C  302  LEU C  306  5                                   5    
HELIX  385 BQ7 ASN C  321  LYS C  335  1                                  15    
HELIX  386 BQ8 ASN C  343  MET C  351  1                                   9    
HELIX  387 BQ9 ALA C  357  GLU C  373  1                                  17    
HELIX  388 BR1 THR C  379  MET C  391  1                                  13    
HELIX  389 BR2 GLN D   48  GLU D   78  1                                  31    
HELIX  390 BR3 MET D  170  HIS D  187  1                                  18    
HELIX  391 BR4 GLU D  189  ILE D  194  1                                   6    
HELIX  392 BR5 THR D  213  THR D  223  1                                  11    
HELIX  393 BR6 GLY D  241  ALA D  258  1                                  18    
HELIX  394 BR7 ALA D  281  ASP D  297  1                                  17    
HELIX  395 BR8 GLN D  340  ILE D  348  1                                   9    
HELIX  396 BR9 ASP D  374  GLU D  389  1                                  16    
HELIX  397 BS1 ALA D  396  ALA D  402  1                                   7    
HELIX  398 BS2 LEU E   16  LEU E   50  1                                  35    
HELIX  399 BS3 ASP E   88  LEU E   92  5                                   5    
HELIX  400 BS4 VAL E  119  HIS E  124  1                                   6    
HELIX  401 BS5 LEU E  138  GLU E  150  1                                  13    
HELIX  402 BS6 GLU E  150  ASN E  155  1                                   6    
HELIX  403 BS7 LEU E  158  GLY E  163  1                                   6    
HELIX  404 BS8 GLY E  179  LEU E  191  1                                  13    
HELIX  405 BS9 GLY E  209  HIS E  225  1                                  17    
HELIX  406 BT1 THR E  247  MET E  264  1                                  18    
HELIX  407 BT2 ASN E  305  ALA E  317  1                                  13    
HELIX  408 BT3 ASP E  327  LEU E  334  1                                   8    
HELIX  409 BT4 ASN E  339  ARG E  356  1                                  18    
HELIX  410 BT5 GLN E  364  LYS E  378  1                                  15    
HELIX  411 BT6 LYS E  379  GLU E  381  5                                   3    
HELIX  412 BT7 THR F   45  LYS F   84  1                                  40    
HELIX  413 BT8 ASP F  169  GLU F  176  1                                   8    
HELIX  414 BT9 LEU F  191  HIS F  208  1                                  18    
HELIX  415 BU1 LYS F  209  ASN F  214  1                                   6    
HELIX  416 BU2 LYS F  233  THR F  244  1                                  12    
HELIX  417 BU3 GLY F  253  VAL F  257  5                                   5    
HELIX  418 BU4 ASP F  263  LYS F  278  1                                  16    
HELIX  419 BU5 ARG F  304  ASP F  318  1                                  15    
HELIX  420 BU6 ASP F  339  LEU F  343  5                                   5    
HELIX  421 BU7 GLU F  359  SER F  370  1                                  12    
HELIX  422 BU8 ASN F  380  CYS F  387  1                                   8    
HELIX  423 BU9 ASN F  392  ARG F  410  1                                  19    
HELIX  424 BV1 THR F  416  LEU F  425  1                                  10    
HELIX  425 BV2 VAL f   11  SER f   16  5                                   6    
HELIX  426 BV3 ALA f   19  ARG f   33  1                                  15    
HELIX  427 BV4 ARG f   34  ALA f   36  5                                   3    
HELIX  428 BV5 GLU f   44  ASP f   49  1                                   6    
HELIX  429 BV6 LYS f   50  GLN f   53  5                                   4    
HELIX  430 BV7 TYR f   71  THR f   87  1                                  17    
HELIX  431 BV8 PRO f   93  PHE f   98  1                                   6    
HELIX  432 BV9 LYS f  119  ILE f  126  1                                   8    
HELIX  433 BW1 ILE f  126  VAL f  145  1                                  20    
HELIX  434 BW2 GLY f  164  ARG f  181  1                                  18    
HELIX  435 BW3 LEU f  184  VAL f  192  1                                   9    
HELIX  436 BW4 LEU f  208  LEU f  217  1                                  10    
HELIX  437 BW5 ILE f  221  TYR f  239  1                                  19    
HELIX  438 BW6 GLU f  242  PHE f  259  1                                  18    
HELIX  439 BW7 PHE f  262  ASN f  273  1                                  12    
HELIX  440 BW8 MET f  275  VAL f  288  1                                  14    
HELIX  441 BW9 LEU f  298  GLU f  309  1                                  12    
HELIX  442 BX1 GLU f  312  VAL f  324  1                                  13    
HELIX  443 BX2 SER f  328  ALA f  334  1                                   7    
HELIX  444 BX3 PRO f  342  THR f  351  1                                  10    
HELIX  445 BX4 ASN f  355  GLY f  360  1                                   6    
HELIX  446 BX5 ARG f  369  PHE f  380  1                                  12    
HELIX  447 BX6 LYS f  403  ILE f  417  1                                  15    
HELIX  448 BX7 ASP f  421  LEU f  433  1                                  13    
HELIX  449 BX8 GLU f  437  ASN f  452  1                                  16    
HELIX  450 BX9 GLU f  458  ALA f  464  1                                   7    
HELIX  451 BY1 HIS f  472  SER f  474  5                                   3    
HELIX  452 BY2 ASN f  475  TYR f  489  1                                  15    
HELIX  453 BY3 GLU f  495  GLY f  506  1                                  12    
HELIX  454 BY4 MET f  512  VAL f  527  1                                  16    
HELIX  455 BY5 THR f  535  GLU f  544  1                                  10    
HELIX  456 BY6 THR f  553  LEU f  567  1                                  15    
HELIX  457 BY7 ILE f  573  VAL f  583  1                                  11    
HELIX  458 BY8 GLU f  585  ALA f  599  1                                  15    
HELIX  459 BY9 VAL f  606  CYS f  616  1                                  11    
HELIX  460 BZ1 SER f  622  ASP f  630  1                                   9    
HELIX  461 BZ2 ASP f  630  LYS f  635  1                                   6    
HELIX  462 BZ3 VAL f  652  GLY f  663  1                                  12    
HELIX  463 BZ4 ALA f  668  ARG f  680  1                                  13    
HELIX  464 BZ5 ALA f  689  ILE f  697  1                                   9    
HELIX  465 BZ6 ALA f  717  ALA f  728  1                                  12    
HELIX  466 BZ7 ARG f  740  LYS f  754  1                                  15    
HELIX  467 BZ8 GLY f  774  THR f  777  5                                   4    
HELIX  468 BZ9 LEU f  778  ARG f  785  1                                   8    
HELIX  469 CA1 GLN f  790  GLY f  795  1                                   6    
SHEET    1 AA1 2 VAL U 744  ILE U 746  0                                        
SHEET    2 AA1 2 TYR U 783  PRO U 785 -1  O  THR U 784   N  THR U 745           
SHEET    1 AA2 3 ALA U 882  ARG U 883  0                                        
SHEET    2 AA2 3 CYS U 787  GLY U 790 -1  N  VAL U 788   O  ALA U 882           
SHEET    3 AA2 3 GLY U 910  ILE U 912  1  O  GLY U 910   N  CYS U 787           
SHEET    1 AA3 2 LYS U 803  SER U 804  0                                        
SHEET    2 AA3 2 LEU U 892  THR U 893 -1  O  THR U 893   N  LYS U 803           
SHEET    1 AA4 2 SER V 450  ILE V 451  0                                        
SHEET    2 AA4 2 VAL V 458  GLN V 459 -1  O  GLN V 459   N  SER V 450           
SHEET    1 AA5 3 VAL X 345  GLN X 346  0                                        
SHEET    2 AA5 3 VAL X 384  ILE X 387 -1  O  LEU X 385   N  VAL X 345           
SHEET    3 AA5 3 GLY X 376  ILE X 377 -1  N  ILE X 377   O  ILE X 386           
SHEET    1 AA6 3 VAL Z  36  LEU Z  40  0                                        
SHEET    2 AA6 3 ILE Z  91  HIS Z  96 -1  O  TYR Z  95   N  GLY Z  37           
SHEET    3 AA6 3 VAL Z 120  ILE Z 123  1  O  VAL Z 120   N  TRP Z  94           
SHEET    1 AA7 2 TYR Z 138  ILE Z 139  0                                        
SHEET    2 AA7 2 GLU Z 156  HIS Z 157 -1  O  GLU Z 156   N  ILE Z 139           
SHEET    1 AA8 2 GLN a 290  LEU a 291  0                                        
SHEET    2 AA8 2 VAL a 331  HIS a 332 -1  O  VAL a 331   N  LEU a 291           
SHEET    1 AA9 3 SER b   5  VAL b   8  0                                        
SHEET    2 AA9 3 MET b 107  ILE b 110  1  O  ILE b 110   N  MET b   7           
SHEET    3 AA9 3 VAL b 136  VAL b 138  1  O  ASN b 137   N  MET b 107           
SHEET    1 AB1 3 PHE b 112  VAL b 113  0                                        
SHEET    2 AB1 3 ILE b 140  ASN b 142  1  O  ILE b 141   N  VAL b 113           
SHEET    3 AB1 3 LEU b 170  VAL b 171  1  O  VAL b 171   N  ILE b 140           
SHEET    1 AB2 5 MET c 107  GLY c 110  0                                        
SHEET    2 AB2 5 MET c  57  GLU c  60 -1  N  MET c  57   O  GLY c 110           
SHEET    3 AB2 5 VAL c  67  VAL c  72 -1  O  ASP c  71   N  LEU c  58           
SHEET    4 AB2 5 VAL c  31  ILE c  33  1  N  TYR c  32   O  VAL c  67           
SHEET    5 AB2 5 ILE c 205  TYR c 207  1  O  ASN c 206   N  ILE c  33           
SHEET    1 AB3 2 VAL c  53  MET c  54  0                                        
SHEET    2 AB3 2 HIS c 113  SER c 114 -1  O  SER c 114   N  VAL c  53           
SHEET    1 AB4 3 ALA c 142  VAL c 144  0                                        
SHEET    2 AB4 3 ASP c 158  LEU c 162 -1  O  ASP c 158   N  VAL c 144           
SHEET    3 AB4 3 TYR c 200  SER c 202 -1  O  TYR c 201   N  ARG c 161           
SHEET    1 AB5 2 VAL d 216  GLY d 218  0                                        
SHEET    2 AB5 2 ASN d 221  TYR d 223 -1  O  ASN d 221   N  GLY d 218           
SHEET    1 AB6 5 ALA G 165  GLY G 169  0                                        
SHEET    2 AB6 5 THR G  38  VAL G  42 -1  N  ALA G  41   O  THR G 166           
SHEET    3 AB6 5 CYS G  47  GLN G  53 -1  O  VAL G  51   N  VAL G  40           
SHEET    4 AB6 5 ILE G 215  THR G 221 -1  O  GLY G 218   N  ILE G  50           
SHEET    5 AB6 5 ASN G 224  ILE G 229 -1  O  ARG G 228   N  VAL G 219           
SHEET    1 AB7 4 PHE G  70  THR G  73  0                                        
SHEET    2 AB7 4 ILE G  76  MET G  80 -1  O  ILE G  76   N  THR G  73           
SHEET    3 AB7 4 MET G 138  ASP G 144 -1  O  ILE G 141   N  GLY G  77           
SHEET    4 AB7 4 GLY G 148  CYS G 154 -1  O  GLY G 148   N  ASP G 144           
SHEET    1 AB8 5 ALA H 160  MET H 163  0                                        
SHEET    2 AB8 5 SER H  35  LYS H  39 -1  N  GLY H  37   O  THR H 161           
SHEET    3 AB8 5 VAL H  44  GLU H  49 -1  O  ALA H  47   N  VAL H  36           
SHEET    4 AB8 5 ILE H 208  ASN H 214 -1  O  GLY H 211   N  LEU H  46           
SHEET    5 AB8 5 GLY H 217  ARG H 220 -1  O  ARG H 219   N  ILE H 212           
SHEET    1 AB9 4 GLU H  66  THR H  69  0                                        
SHEET    2 AB9 4 ILE H  72  GLY H  78 -1  O  ILE H  72   N  ILE H  68           
SHEET    3 AB9 4 VAL H 132  TRP H 139 -1  O  CYS H 137   N  GLY H  73           
SHEET    4 AB9 4 PRO H 144  GLN H 148 -1  O  PHE H 147   N  ILE H 136           
SHEET    1 AC1 4 CYS I  34  GLY I  36  0                                        
SHEET    2 AC1 4 VAL I  43  GLU I  48 -1  O  ALA I  46   N  LEU I  35           
SHEET    3 AC1 4 VAL I 211  LEU I 216 -1  O  LEU I 216   N  VAL I  43           
SHEET    4 AC1 4 ILE I 225  ARG I 226 -1  O  ARG I 226   N  THR I 215           
SHEET    1 AC2 4 MET I  72  ALA I  73  0                                        
SHEET    2 AC2 4 LEU I 135  GLY I 138 -1  O  ILE I 137   N  ALA I  73           
SHEET    3 AC2 4 GLN I 146  SER I 150 -1  O  GLN I 146   N  GLY I 138           
SHEET    4 AC2 4 TYR I 156  GLY I 157 -1  O  GLY I 157   N  GLN I 149           
SHEET    1 AC3 2 ALA I  77  GLY I  78  0                                        
SHEET    2 AC3 2 VAL I 132  SER I 133 -1  O  SER I 133   N  ALA I  77           
SHEET    1 AC4 5 ALA J 158  ALA J 160  0                                        
SHEET    2 AC4 5 ALA J  32  ARG J  36 -1  N  GLY J  34   O  ASN J 159           
SHEET    3 AC4 5 VAL J  41  VAL J  45 -1  O  VAL J  42   N  VAL J  35           
SHEET    4 AC4 5 GLU J 207  MET J 211 -1  O  MET J 211   N  VAL J  41           
SHEET    5 AC4 5 LYS J 218  ILE J 219 -1  O  LYS J 218   N  VAL J 210           
SHEET    1 AC5 4 VAL J  69  CYS J  70  0                                        
SHEET    2 AC5 4 LEU J 132  PHE J 136 -1  O  VAL J 134   N  CYS J  70           
SHEET    3 AC5 4 PRO J 142  GLN J 146 -1  O  TYR J 145   N  ILE J 133           
SHEET    4 AC5 4 HIS J 154  TRP J 156 -1  O  TRP J 156   N  LEU J 144           
SHEET    1 AC6 3 ALA K  37  THR K  42  0                                        
SHEET    2 AC6 3 GLY K  45  GLU K  51 -1  O  ALA K  49   N  ILE K  38           
SHEET    3 AC6 3 ILE K 215  LEU K 217 -1  O  GLU K 216   N  VAL K  50           
SHEET    1 AC7 3 LEU K 142  ASP K 147  0                                        
SHEET    2 AC7 3 GLY K 150  HIS K 155 -1  O  PHE K 154   N  PHE K 143           
SHEET    3 AC7 3 VAL K 163  GLN K 164 -1  O  VAL K 163   N  HIS K 155           
SHEET    1 AC8 5 ALA L 158  ILE L 161  0                                        
SHEET    2 AC8 5 THR L  35  LYS L  39 -1  N  GLY L  37   O  MET L 159           
SHEET    3 AC8 5 HIS L  43  LEU L  49 -1  O  VAL L  47   N  VAL L  36           
SHEET    4 AC8 5 VAL L 210  GLY L 216 -1  O  GLY L 213   N  LEU L  46           
SHEET    5 AC8 5 THR L 222  TYR L 224 -1  O  THR L 222   N  ILE L 214           
SHEET    1 AC9 5 LEU L  64  HIS L  65  0                                        
SHEET    2 AC9 5 GLY L  71  SER L  73 -1  O  ILE L  72   N  LEU L  64           
SHEET    3 AC9 5 LEU L 133  ASP L 138 -1  O  ALA L 135   N  GLY L  71           
SHEET    4 AC9 5 GLY L 141  GLN L 146 -1  O  PHE L 145   N  ILE L 134           
SHEET    5 AC9 5 PHE L 154  CYS L 156 -1  O  PHE L 154   N  GLN L 146           
SHEET    1 AD1 4 GLY M 162  ILE M 165  0                                        
SHEET    2 AD1 4 ALA M  36  CYS M  41 -1  N  ALA M  36   O  ILE M 165           
SHEET    3 AD1 4 GLY M  44  LEU M  52 -1  O  GLY M  44   N  CYS M  41           
SHEET    4 AD1 4 PHE M 209  GLU M 212 -1  O  GLU M 210   N  LYS M  51           
SHEET    1 AD2 5 GLY M 162  ILE M 165  0                                        
SHEET    2 AD2 5 ALA M  36  CYS M  41 -1  N  ALA M  36   O  ILE M 165           
SHEET    3 AD2 5 GLY M  44  LEU M  52 -1  O  GLY M  44   N  CYS M  41           
SHEET    4 AD2 5 SER M 214  GLY M 217 -1  O  VAL M 216   N  VAL M  45           
SHEET    5 AD2 5 HIS M 224  ILE M 226 -1  O  GLU M 225   N  TRP M 215           
SHEET    1 AD3 4 ALA M  78  GLY M  79  0                                        
SHEET    2 AD3 4 CYS M 133  SER M 141 -1  O  SER M 134   N  ALA M  78           
SHEET    3 AD3 4 GLY M 145  ILE M 151 -1  O  TYR M 149   N  LEU M 137           
SHEET    4 AD3 4 SER M 157  GLY M 159 -1  O  TYR M 158   N  MET M 150           
SHEET    1 AD4 5 PHE N 125  GLY N 128  0                                        
SHEET    2 AD4 5 ILE N   3  GLN N   7 -1  N  ILE N   3   O  GLY N 128           
SHEET    3 AD4 5 VAL N  12  ALA N  16 -1  O  VAL N  13   N  VAL N   6           
SHEET    4 AD4 5 ILE N 174  ILE N 179 -1  O  ALA N 177   N  LEU N  14           
SHEET    5 AD4 5 VAL N 184  LEU N 189 -1  O  GLU N 185   N  ALA N 178           
SHEET    1 AD5 2 THR N  20  THR N  22  0                                        
SHEET    2 AD5 2 TYR N  25  ASN N  28 -1  O  TYR N  25   N  THR N  22           
SHEET    1 AD6 5 LEU N  34  PRO N  36  0                                        
SHEET    2 AD6 5 ILE N  41  CYS N  44 -1  O  CYS N  43   N  THR N  35           
SHEET    3 AD6 5 ILE N  99  ASP N 104 -1  O  ALA N 101   N  PHE N  42           
SHEET    4 AD6 5 GLY N 108  SER N 113 -1  O  TYR N 112   N  ILE N 100           
SHEET    5 AD6 5 VAL N 121  ARG N 122 -1  O  VAL N 121   N  SER N 113           
SHEET    1 AD7 5 TYR O 124  GLY O 128  0                                        
SHEET    2 AD7 5 THR O   2  VAL O   7 -1  N  ILE O   3   O  MET O 127           
SHEET    3 AD7 5 ILE O  12  ALA O  16 -1  O  GLY O  15   N  ALA O   4           
SHEET    4 AD7 5 ASP O 174  ILE O 178 -1  O  ILE O 178   N  ILE O  12           
SHEET    5 AD7 5 LEU O 183  LEU O 186 -1  O  ASP O 184   N  VAL O 177           
SHEET    1 AD8 2 ALA O  20  GLU O  22  0                                        
SHEET    2 AD8 2 VAL O  25  ASP O  28 -1  O  VAL O  25   N  GLU O  22           
SHEET    1 AD9 5 ILE O  34  PHE O  36  0                                        
SHEET    2 AD9 5 ILE O  41  GLY O  47 -1  O  CYS O  43   N  HIS O  35           
SHEET    3 AD9 5 ALA O  96  VAL O 103 -1  O  GLY O 101   N  TYR O  42           
SHEET    4 AD9 5 PRO O 108  TYR O 114 -1  O  TYR O 111   N  LEU O 100           
SHEET    5 AD9 5 SER O 118  LYS O 121 -1  O  SER O 118   N  TYR O 114           
SHEET    1 AE1 3 VAL O 211  THR O 213  0                                        
SHEET    2 AE1 3 LYS P 194  LEU P 200 -1  O  THR P 199   N  LEU O 212           
SHEET    3 AE1 3 ILE O 216  PRO O 218 -1  N  THR O 217   O  ILE P 195           
SHEET    1 AE2 6 VAL O 211  THR O 213  0                                        
SHEET    2 AE2 6 LYS P 194  LEU P 200 -1  O  THR P 199   N  LEU O 212           
SHEET    3 AE2 6 VAL P 185  ILE P 190 -1  N  ILE P 189   O  THR P 196           
SHEET    4 AE2 6 VAL P  20  ASP P  25 -1  N  ILE P  22   O  HIS P 188           
SHEET    5 AE2 6 ALA P  10  LYS P  15 -1  N  MET P  12   O  ALA P  23           
SHEET    6 AE2 6 PHE P 136  GLY P 140 -1  O  VAL P 137   N  ALA P  13           
SHEET    1 AE3 2 PHE P  28  GLY P  29  0                                        
SHEET    2 AE3 2 MET P  34  THR P  36 -1  O  VAL P  35   N  PHE P  28           
SHEET    1 AE4 5 ILE P  42  PRO P  44  0                                        
SHEET    2 AE4 5 LEU P  49  GLY P  52 -1  O  ILE P  51   N  PHE P  43           
SHEET    3 AE4 5 VAL P 108  LEU P 112 -1  O  VAL P 108   N  GLY P  52           
SHEET    4 AE4 5 PRO P 119  SER P 123 -1  O  PHE P 120   N  GLY P 111           
SHEET    5 AE4 5 MET P 131  VAL P 132 -1  O  MET P 131   N  SER P 123           
SHEET    1 AE5 4 ILE Q   5  GLN Q   8  0                                        
SHEET    2 AE5 4 VAL Q  13  ASP Q  18 -1  O  LEU Q  14   N  ILE Q   7           
SHEET    3 AE5 4 THR Q 177  ILE Q 183 -1  O  ARG Q 181   N  VAL Q  15           
SHEET    4 AE5 4 ILE Q 188  ASP Q 190 -1  O  HIS Q 189   N  ILE Q 182           
SHEET    1 AE6 4 ILE Q   5  GLN Q   8  0                                        
SHEET    2 AE6 4 VAL Q  13  ASP Q  18 -1  O  LEU Q  14   N  ILE Q   7           
SHEET    3 AE6 4 THR Q 177  ILE Q 183 -1  O  ARG Q 181   N  VAL Q  15           
SHEET    4 AE6 4 ILE Q 194  SER Q 195 -1  O  ILE Q 194   N  PHE Q 178           
SHEET    1 AE7 3 LEU Q  43  GLY Q  48  0                                        
SHEET    2 AE7 3 VAL Q 100  ASP Q 108 -1  O  ALA Q 105   N  LEU Q  43           
SHEET    3 AE7 3 GLY Q 112  LEU Q 115 -1  O  GLY Q 112   N  ASP Q 108           
SHEET    1 AE8 5 THR R 125  GLY R 129  0                                        
SHEET    2 AE8 5 THR R   2  PHE R   8 -1  N  THR R   3   O  VAL R 128           
SHEET    3 AE8 5 GLY R  11  ALA R  16 -1  O  GLY R  11   N  PHE R   8           
SHEET    4 AE8 5 VAL R 174  VAL R 179 -1  O  TYR R 177   N  VAL R  14           
SHEET    5 AE8 5 TRP R 184  ASP R 190 -1  O  ASP R 190   N  VAL R 174           
SHEET    1 AE9 2 ALA R  20  ALA R  22  0                                        
SHEET    2 AE9 2 TYR R  25  SER R  28 -1  O  TYR R  25   N  ALA R  22           
SHEET    1 AF1 4 LEU R  41  GLY R  43  0                                        
SHEET    2 AF1 4 MET R 100  TRP R 104 -1  O  CYS R 102   N  LEU R  42           
SHEET    3 AF1 4 PRO R 109  TYR R 113 -1  O  TYR R 112   N  ILE R 101           
SHEET    4 AF1 4 ILE R 121  SER R 122 -1  O  ILE R 121   N  TYR R 113           
SHEET    1 AF2 5 PHE S 135  GLY S 139  0                                        
SHEET    2 AF2 5 THR S  11  ALA S  16 -1  N  ILE S  12   O  GLY S 138           
SHEET    3 AF2 5 ALA S  21  SER S  25 -1  O  ALA S  24   N  LEU S  13           
SHEET    4 AF2 5 ARG S 194  THR S 199 -1  O  CYS S 196   N  VAL S  23           
SHEET    5 AF2 5 GLY S 202  THR S 207 -1  O  ARG S 204   N  ILE S 197           
SHEET    1 AF3 2 LEU S  29  SER S  30  0                                        
SHEET    2 AF3 2 ILE S  35  THR S  37 -1  O  HIS S  36   N  LEU S  29           
SHEET    1 AF4 5 CYS S  43  THR S  47  0                                        
SHEET    2 AF4 5 THR S  50  GLY S  56 -1  O  ILE S  52   N  TYR S  44           
SHEET    3 AF4 5 VAL S 106  LEU S 113 -1  O  GLY S 111   N  VAL S  51           
SHEET    4 AF4 5 GLY S 119  SER S 123 -1  O  TYR S 122   N  ILE S 110           
SHEET    5 AF4 5 GLN S 131  ASP S 133 -1  O  ASP S 133   N  VAL S 121           
SHEET    1 AF5 5 SER T 136  ALA T 138  0                                        
SHEET    2 AF5 5 LEU T  12  PHE T  16 -1  N  GLY T  13   O  LEU T 137           
SHEET    3 AF5 5 GLY T  19  ASP T  25 -1  O  GLY T  19   N  PHE T  16           
SHEET    4 AF5 5 PHE T 187  THR T 193 -1  O  ALA T 190   N  ILE T  22           
SHEET    5 AF5 5 GLY T 196  LEU T 203 -1  O  GLU T 200   N  ILE T 189           
SHEET    1 AF6 5 ILE T  42  MET T  43  0                                        
SHEET    2 AF6 5 THR T  49  GLY T  55 -1  O  LEU T  51   N  MET T  43           
SHEET    3 AF6 5 ASN T 108  ALA T 116 -1  O  VAL T 111   N  GLY T  52           
SHEET    4 AF6 5 GLU T 119  VAL T 125 -1  O  PHE T 121   N  GLY T 114           
SHEET    5 AF6 5 ALA T 131  GLU T 133 -1  O  TYR T 132   N  TYR T 124           
SHEET    1 AF7 5 ALA g 165  GLY g 169  0                                        
SHEET    2 AF7 5 THR g  38  VAL g  42 -1  N  ALA g  41   O  THR g 166           
SHEET    3 AF7 5 CYS g  47  GLN g  53 -1  O  VAL g  51   N  VAL g  40           
SHEET    4 AF7 5 ILE g 215  THR g 221 -1  O  GLY g 218   N  ILE g  50           
SHEET    5 AF7 5 ASN g 224  ILE g 229 -1  O  ARG g 228   N  VAL g 219           
SHEET    1 AF8 5 PHE g  70  THR g  73  0                                        
SHEET    2 AF8 5 ILE g  76  MET g  80 -1  O  CYS g  78   N  PHE g  70           
SHEET    3 AF8 5 MET g 138  ASP g 144 -1  O  ILE g 141   N  GLY g  77           
SHEET    4 AF8 5 GLY g 148  CYS g 154 -1  O  GLY g 148   N  ASP g 144           
SHEET    5 AF8 5 CYS g 161  GLY g 162 -1  O  CYS g 161   N  LYS g 153           
SHEET    1 AF9 5 ALA h 160  MET h 163  0                                        
SHEET    2 AF9 5 SER h  35  LYS h  39 -1  N  GLY h  37   O  THR h 161           
SHEET    3 AF9 5 VAL h  44  GLU h  49 -1  O  VAL h  45   N  ILE h  38           
SHEET    4 AF9 5 ILE h 208  ASN h 214 -1  O  GLY h 211   N  LEU h  46           
SHEET    5 AF9 5 GLY h 217  ARG h 220 -1  O  ARG h 219   N  ILE h 212           
SHEET    1 AG1 4 GLU h  66  PRO h  67  0                                        
SHEET    2 AG1 4 ILE h  72  VAL h  75 -1  O  LEU h  74   N  GLU h  66           
SHEET    3 AG1 4 LEU h 135  TRP h 139 -1  O  CYS h 137   N  GLY h  73           
SHEET    4 AG1 4 PRO h 144  GLN h 148 -1  O  PHE h 147   N  ILE h 136           
SHEET    1 AG2 4 CYS i  34  GLY i  36  0                                        
SHEET    2 AG2 4 VAL i  43  GLU i  48 -1  O  ALA i  46   N  LEU i  35           
SHEET    3 AG2 4 VAL i 211  LEU i 216 -1  O  ALA i 214   N  LEU i  45           
SHEET    4 AG2 4 ILE i 225  VAL i 227 -1  O  ARG i 226   N  THR i 215           
SHEET    1 AG3 3 MET i  72  ALA i  73  0                                        
SHEET    2 AG3 3 SER i 133  GLY i 138 -1  O  ILE i 137   N  ALA i  73           
SHEET    3 AG3 3 VAL i  76  ALA i  77 -1  N  ALA i  77   O  SER i 133           
SHEET    1 AG4 4 MET i  72  ALA i  73  0                                        
SHEET    2 AG4 4 SER i 133  GLY i 138 -1  O  ILE i 137   N  ALA i  73           
SHEET    3 AG4 4 GLN i 146  SER i 150 -1  O  GLN i 146   N  GLY i 138           
SHEET    4 AG4 4 TYR i 156  GLY i 158 -1  O  GLY i 157   N  GLN i 149           
SHEET    1 AG5 5 ALA j 158  ILE j 161  0                                        
SHEET    2 AG5 5 ALA j  32  ARG j  36 -1  N  ALA j  32   O  ILE j 161           
SHEET    3 AG5 5 VAL j  41  VAL j  45 -1  O  VAL j  42   N  VAL j  35           
SHEET    4 AG5 5 GLU j 207  MET j 211 -1  O  MET j 211   N  VAL j  41           
SHEET    5 AG5 5 LYS j 218  ILE j 219 -1  O  LYS j 218   N  VAL j 210           
SHEET    1 AG6 4 VAL j  69  CYS j  70  0                                        
SHEET    2 AG6 4 LEU j 132  PHE j 136 -1  O  VAL j 134   N  CYS j  70           
SHEET    3 AG6 4 PRO j 142  GLN j 146 -1  O  TYR j 145   N  ILE j 133           
SHEET    4 AG6 4 HIS j 154  TRP j 156 -1  O  TRP j 156   N  LEU j 144           
SHEET    1 AG7 4 ALA k 167  ALA k 169  0                                        
SHEET    2 AG7 4 ALA k  37  ILE k  40 -1  N  GLY k  39   O  ARG k 168           
SHEET    3 AG7 4 CYS k  47  GLU k  51 -1  O  ALA k  49   N  ILE k  38           
SHEET    4 AG7 4 ILE k 215  LEU k 217 -1  O  GLU k 216   N  VAL k  50           
SHEET    1 AG8 4 ILE k  74  ALA k  77  0                                        
SHEET    2 AG8 4 LEU k 142  ASP k 147 -1  O  GLY k 144   N  GLY k  75           
SHEET    3 AG8 4 GLY k 150  HIS k 155 -1  O  PHE k 154   N  PHE k 143           
SHEET    4 AG8 4 VAL k 163  GLN k 164 -1  O  VAL k 163   N  HIS k 155           
SHEET    1 AG9 5 ALA l 158  ILE l 161  0                                        
SHEET    2 AG9 5 THR l  35  LYS l  39 -1  N  GLY l  37   O  MET l 159           
SHEET    3 AG9 5 HIS l  43  LEU l  49 -1  O  VAL l  47   N  VAL l  36           
SHEET    4 AG9 5 VAL l 210  GLY l 216 -1  O  VAL l 215   N  ALA l  44           
SHEET    5 AG9 5 THR l 222  TYR l 224 -1  O  THR l 222   N  ILE l 214           
SHEET    1 AH1 5 LEU l  64  HIS l  65  0                                        
SHEET    2 AH1 5 GLY l  71  SER l  73 -1  O  ILE l  72   N  LEU l  64           
SHEET    3 AH1 5 LEU l 133  ASP l 138 -1  O  ALA l 135   N  GLY l  71           
SHEET    4 AH1 5 GLY l 141  GLN l 146 -1  O  PHE l 145   N  ILE l 134           
SHEET    5 AH1 5 PHE l 154  ASP l 155 -1  O  PHE l 154   N  GLN l 146           
SHEET    1 AH2 4 GLY m 162  ILE m 165  0                                        
SHEET    2 AH2 4 ALA m  36  CYS m  41 -1  N  ALA m  36   O  ILE m 165           
SHEET    3 AH2 4 GLY m  44  LEU m  52 -1  O  GLY m  44   N  CYS m  41           
SHEET    4 AH2 4 PHE m 209  GLU m 212 -1  O  GLU m 210   N  LYS m  51           
SHEET    1 AH3 5 GLY m 162  ILE m 165  0                                        
SHEET    2 AH3 5 ALA m  36  CYS m  41 -1  N  ALA m  36   O  ILE m 165           
SHEET    3 AH3 5 GLY m  44  LEU m  52 -1  O  GLY m  44   N  CYS m  41           
SHEET    4 AH3 5 SER m 214  GLY m 217 -1  O  VAL m 216   N  VAL m  45           
SHEET    5 AH3 5 HIS m 224  ILE m 226 -1  O  GLU m 225   N  TRP m 215           
SHEET    1 AH4 3 GLY m  74  MET m  75  0                                        
SHEET    2 AH4 3 CYS m 133  SER m 141 -1  O  GLY m 138   N  GLY m  74           
SHEET    3 AH4 3 ALA m  78  GLY m  79 -1  N  ALA m  78   O  SER m 134           
SHEET    1 AH5 4 GLY m  74  MET m  75  0                                        
SHEET    2 AH5 4 CYS m 133  SER m 141 -1  O  GLY m 138   N  GLY m  74           
SHEET    3 AH5 4 GLY m 145  ILE m 151 -1  O  TYR m 149   N  LEU m 137           
SHEET    4 AH5 4 SER m 157  GLY m 159 -1  O  TYR m 158   N  MET m 150           
SHEET    1 AH6 5 PHE n 125  GLY n 128  0                                        
SHEET    2 AH6 5 ILE n   3  GLN n   7 -1  N  ILE n   3   O  GLY n 128           
SHEET    3 AH6 5 VAL n  12  ALA n  16 -1  O  VAL n  13   N  VAL n   6           
SHEET    4 AH6 5 ILE n 174  ILE n 179 -1  O  ILE n 179   N  VAL n  12           
SHEET    5 AH6 5 VAL n 184  LEU n 189 -1  O  GLU n 185   N  ALA n 178           
SHEET    1 AH7 2 THR n  20  THR n  22  0                                        
SHEET    2 AH7 2 TYR n  25  ASN n  28 -1  O  TYR n  25   N  THR n  22           
SHEET    1 AH8 5 LEU n  34  PRO n  36  0                                        
SHEET    2 AH8 5 ILE n  41  CYS n  44 -1  O  CYS n  43   N  THR n  35           
SHEET    3 AH8 5 ILE n  99  ASP n 104 -1  O  ILE n  99   N  CYS n  44           
SHEET    4 AH8 5 GLY n 108  SER n 113 -1  O  TYR n 112   N  ILE n 100           
SHEET    5 AH8 5 VAL n 121  GLN n 123 -1  O  GLN n 123   N  VAL n 111           
SHEET    1 AH9 5 TYR o 124  GLY o 128  0                                        
SHEET    2 AH9 5 THR o   2  VAL o   7 -1  N  GLY o   5   O  VAL o 125           
SHEET    3 AH9 5 ILE o  12  ALA o  16 -1  O  GLY o  15   N  ALA o   4           
SHEET    4 AH9 5 ASP o 174  ILE o 178 -1  O  CYS o 176   N  LEU o  14           
SHEET    5 AH9 5 LEU o 183  LEU o 186 -1  O  ASP o 184   N  VAL o 177           
SHEET    1 AI1 2 THR o  21  GLU o  22  0                                        
SHEET    2 AI1 2 VAL o  25  VAL o  26 -1  O  VAL o  25   N  GLU o  22           
SHEET    1 AI2 5 ILE o  34  PHE o  36  0                                        
SHEET    2 AI2 5 ILE o  41  GLY o  47 -1  O  CYS o  43   N  HIS o  35           
SHEET    3 AI2 5 ALA o  96  VAL o 103 -1  O  GLY o 101   N  TYR o  42           
SHEET    4 AI2 5 PRO o 108  TYR o 114 -1  O  ILE o 113   N  LEU o  98           
SHEET    5 AI2 5 SER o 118  LYS o 121 -1  O  SER o 118   N  TYR o 114           
SHEET    1 AI3 3 VAL o 211  THR o 213  0                                        
SHEET    2 AI3 3 LYS p 194  LEU p 200 -1  O  THR p 199   N  LEU o 212           
SHEET    3 AI3 3 ILE o 216  PRO o 218 -1  N  THR o 217   O  ILE p 195           
SHEET    1 AI4 6 VAL o 211  THR o 213  0                                        
SHEET    2 AI4 6 LYS p 194  LEU p 200 -1  O  THR p 199   N  LEU o 212           
SHEET    3 AI4 6 VAL p 185  ILE p 190 -1  N  ILE p 189   O  THR p 196           
SHEET    4 AI4 6 VAL p  20  ASP p  25 -1  N  ILE p  22   O  HIS p 188           
SHEET    5 AI4 6 ALA p  10  LYS p  15 -1  N  MET p  14   O  ALA p  21           
SHEET    6 AI4 6 PHE p 136  GLY p 140 -1  O  VAL p 137   N  ALA p  13           
SHEET    1 AI5 2 PHE p  28  GLY p  29  0                                        
SHEET    2 AI5 2 MET p  34  THR p  36 -1  O  VAL p  35   N  PHE p  28           
SHEET    1 AI6 5 ILE p  42  PRO p  44  0                                        
SHEET    2 AI6 5 LEU p  49  GLY p  52 -1  O  ILE p  51   N  PHE p  43           
SHEET    3 AI6 5 VAL p 108  LEU p 112 -1  O  VAL p 108   N  GLY p  52           
SHEET    4 AI6 5 PRO p 119  SER p 123 -1  O  PHE p 120   N  GLY p 111           
SHEET    5 AI6 5 MET p 131  VAL p 132 -1  O  MET p 131   N  SER p 123           
SHEET    1 AI7 4 LEU q   4  GLN q   8  0                                        
SHEET    2 AI7 4 VAL q  13  ASP q  18 -1  O  LEU q  14   N  ILE q   7           
SHEET    3 AI7 4 THR q 177  ILE q 183 -1  O  ARG q 181   N  VAL q  15           
SHEET    4 AI7 4 ILE q 188  ASP q 190 -1  O  HIS q 189   N  ILE q 182           
SHEET    1 AI8 4 LEU q   4  GLN q   8  0                                        
SHEET    2 AI8 4 VAL q  13  ASP q  18 -1  O  LEU q  14   N  ILE q   7           
SHEET    3 AI8 4 THR q 177  ILE q 183 -1  O  ARG q 181   N  VAL q  15           
SHEET    4 AI8 4 ILE q 194  SER q 195 -1  O  ILE q 194   N  PHE q 178           
SHEET    1 AI9 3 ILE q  42  GLY q  48  0                                        
SHEET    2 AI9 3 VAL q 100  TYR q 107 -1  O  ALA q 105   N  LEU q  43           
SHEET    3 AI9 3 PRO q 113  LEU q 115 -1  O  ALA q 114   N  GLY q 106           
SHEET    1 AJ1 5 THR r 125  GLY r 129  0                                        
SHEET    2 AJ1 5 THR r   2  PHE r   8 -1  N  THR r   3   O  VAL r 128           
SHEET    3 AJ1 5 GLY r  11  ALA r  16 -1  O  GLY r  11   N  PHE r   8           
SHEET    4 AJ1 5 VAL r 174  VAL r 179 -1  O  TYR r 177   N  VAL r  14           
SHEET    5 AJ1 5 TRP r 184  ASP r 190 -1  O  ASP r 190   N  VAL r 174           
SHEET    1 AJ2 2 ALA r  20  ALA r  22  0                                        
SHEET    2 AJ2 2 TYR r  25  SER r  28 -1  O  TYR r  25   N  ALA r  22           
SHEET    1 AJ3 4 LEU r  41  GLY r  43  0                                        
SHEET    2 AJ3 4 MET r 100  TRP r 104 -1  O  CYS r 102   N  LEU r  42           
SHEET    3 AJ3 4 PRO r 109  TYR r 113 -1  O  TYR r 112   N  ILE r 101           
SHEET    4 AJ3 4 ILE r 121  SER r 122 -1  O  ILE r 121   N  TYR r 113           
SHEET    1 AJ4 5 PHE s 135  GLY s 139  0                                        
SHEET    2 AJ4 5 THR s  11  ALA s  16 -1  N  ILE s  12   O  GLY s 138           
SHEET    3 AJ4 5 ALA s  21  SER s  25 -1  O  ALA s  24   N  LEU s  13           
SHEET    4 AJ4 5 ARG s 194  THR s 199 -1  O  CYS s 196   N  VAL s  23           
SHEET    5 AJ4 5 GLY s 202  THR s 207 -1  O  ARG s 204   N  ILE s 197           
SHEET    1 AJ5 2 LEU s  29  GLU s  31  0                                        
SHEET    2 AJ5 2 SER s  34  THR s  37 -1  O  HIS s  36   N  LEU s  29           
SHEET    1 AJ6 5 CYS s  43  THR s  47  0                                        
SHEET    2 AJ6 5 THR s  50  GLY s  56 -1  O  ILE s  52   N  TYR s  44           
SHEET    3 AJ6 5 VAL s 106  LEU s 113 -1  O  TYR s 107   N  SER s  55           
SHEET    4 AJ6 5 GLY s 119  SER s 123 -1  O  TYR s 122   N  ILE s 110           
SHEET    5 AJ6 5 GLN s 131  ASP s 133 -1  O  ASP s 133   N  VAL s 121           
SHEET    1 AJ7 5 SER t 136  ALA t 138  0                                        
SHEET    2 AJ7 5 LEU t  12  PHE t  16 -1  N  GLY t  13   O  LEU t 137           
SHEET    3 AJ7 5 GLY t  19  ASP t  25 -1  O  GLY t  19   N  PHE t  16           
SHEET    4 AJ7 5 PHE t 187  THR t 193 -1  O  ALA t 190   N  ILE t  22           
SHEET    5 AJ7 5 GLY t 196  LEU t 203 -1  O  GLU t 200   N  ILE t 189           
SHEET    1 AJ8 5 ILE t  42  MET t  43  0                                        
SHEET    2 AJ8 5 THR t  49  GLY t  55 -1  O  LEU t  51   N  MET t  43           
SHEET    3 AJ8 5 ASN t 108  ALA t 116 -1  O  VAL t 111   N  GLY t  52           
SHEET    4 AJ8 5 GLU t 119  VAL t 125 -1  O  GLY t 123   N  ILE t 112           
SHEET    5 AJ8 5 ALA t 131  GLU t 133 -1  O  TYR t 132   N  TYR t 124           
SHEET    1 AJ9 3 ILE A 101  ALA A 104  0                                        
SHEET    2 AJ9 3 TYR A 111  ASN A 114 -1  O  ILE A 112   N  ILE A 102           
SHEET    3 AJ9 3 LYS A 120  VAL A 122 -1  O  PHE A 121   N  ILE A 113           
SHEET    1 AK1 2 GLY A 141  VAL A 142  0                                        
SHEET    2 AK1 2 ILE A 149  HIS A 150 -1  O  HIS A 150   N  GLY A 141           
SHEET    1 AK2 3 ILE A 238  ARG A 239  0                                        
SHEET    2 AK2 3 CYS A 270  PHE A 274  1  O  LEU A 271   N  ILE A 238           
SHEET    3 AK2 3 ILE A 315  MET A 319  1  O  LEU A 318   N  PHE A 274           
SHEET    1 AK3 3 MET B 107  GLY B 110  0                                        
SHEET    2 AK3 3 VAL B 150  ASN B 153 -1  O  LEU B 152   N  SER B 108           
SHEET    3 AK3 3 GLY B 161  VAL B 162 -1  O  GLY B 161   N  LEU B 151           
SHEET    1 AK4 5 THR B 246  VAL B 251  0                                        
SHEET    2 AK4 5 SER B 280  ASP B 285  1  O  ILE B 281   N  LEU B 248           
SHEET    3 AK4 5 LYS B 326  ALA B 330  1  O  LYS B 326   N  VAL B 282           
SHEET    4 AK4 5 GLY B 221  LEU B 224  1  N  LEU B 224   O  MET B 329           
SHEET    5 AK4 5 ARG B 349  ILE B 351  1  O  ILE B 351   N  ILE B 223           
SHEET    1 AK5 3 VAL C  73  GLY C  74  0                                        
SHEET    2 AK5 3 VAL C 114  LEU C 116 -1  O  VAL C 114   N  GLY C  74           
SHEET    3 AK5 3 LEU C 123  ILE C 126 -1  O  LYS C 125   N  ALA C 115           
SHEET    1 AK6 2 PHE C 247  MET C 248  0                                        
SHEET    2 AK6 2 ILE C 292  MET C 293  1  O  ILE C 292   N  MET C 248           
SHEET    1 AK7 5 ASN D 110  VAL D 113  0                                        
SHEET    2 AK7 5 THR D 100  SER D 105 -1  N  ALA D 101   O  VAL D 113           
SHEET    3 AK7 5 LEU D  87  ASP D  97 -1  N  GLU D  94   O  ILE D 102           
SHEET    4 AK7 5 SER D 129  LEU D 132 -1  O  LEU D 132   N  VAL D  88           
SHEET    5 AK7 5 VAL D 142  LEU D 143 -1  O  LEU D 143   N  SER D 129           
SHEET    1 AK8 8 ASN D 110  VAL D 113  0                                        
SHEET    2 AK8 8 THR D 100  SER D 105 -1  N  ALA D 101   O  VAL D 113           
SHEET    3 AK8 8 LEU D  87  ASP D  97 -1  N  GLU D  94   O  ILE D 102           
SHEET    4 AK8 8 ARG E  78  VAL E  81 -1  O  VAL E  80   N  LEU D  87           
SHEET    5 AK8 8 PHE E  69  ALA E  73 -1  N  VAL E  71   O  TYR E  79           
SHEET    6 AK8 8 ILE E  56  GLN E  63 -1  N  LEU E  61   O  ILE E  70           
SHEET    7 AK8 8 ARG E  97  LEU E 100 -1  O  LEU E 100   N  ILE E  56           
SHEET    8 AK8 8 ILE E 107  LEU E 111 -1  O  ARG E 109   N  ALA E  99           
SHEET    1 AK9 2 VAL D 202  MET D 204  0                                        
SHEET    2 AK9 2 ILE D 308  ALA D 310  1  O  MET D 309   N  MET D 204           
SHEET    1 AL1 2 ILE D 228  VAL D 230  0                                        
SHEET    2 AL1 2 ILE D 262  ILE D 264  1  O  PHE D 263   N  ILE D 228           
SHEET    1 AL2 5 PHE E 195  VAL E 198  0                                        
SHEET    2 AL2 5 ILE E 229  ASP E 233  1  O  PHE E 231   N  VAL E 198           
SHEET    3 AL2 5 LYS E 274  ALA E 278  1  O  ILE E 276   N  ILE E 230           
SHEET    4 AL2 5 GLY E 169  TYR E 173  1  N  LEU E 172   O  MET E 277           
SHEET    5 AL2 5 ARG E 297  HIS E 300  1  O  ILE E 299   N  LEU E 171           
SHEET    1 AL3 5 THR F 131  LEU F 134  0                                        
SHEET    2 AL3 5 CYS F 121  THR F 126 -1  N  ILE F 124   O  TYR F 132           
SHEET    3 AL3 5 VAL F  90  LEU F  97 -1  N  ASN F  92   O  LYS F 125           
SHEET    4 AL3 5 LEU F 150  VAL F 153 -1  O  VAL F 151   N  SER F  91           
SHEET    5 AL3 5 ILE F 160  THR F 163 -1  O  LEU F 161   N  GLY F 152           
SHEET    1 AL4 5 THR F 247  LEU F 251  0                                        
SHEET    2 AL4 5 SER F 281  ASP F 286  1  O  ASP F 286   N  LEU F 251           
SHEET    3 AL4 5 LYS F 327  ALA F 331  1  O  ILE F 329   N  ILE F 283           
SHEET    4 AL4 5 VAL F 223  TYR F 226  1  N  MET F 225   O  ALA F 330           
SHEET    5 AL4 5 ARG F 350  GLU F 353  1  O  ILE F 352   N  TYR F 226           
SSBOND   1 CYS M   41    CYS M  186                          1555   1555  2.03  
SSBOND   2 CYS m   41    CYS m  186                          1555   1555  2.03  
LINK         N   SER c 114                ZN    ZN c 401     1555   1555  2.22  
LINK         O   SER c 114                ZN    ZN c 401     1555   1555  2.23  
CISPEP   1 ALA G    7    GLY G    8          0         2.33                     
CISPEP   2 GLU G   19    GLY G   20          0       -10.26                     
CISPEP   3 SER H    7    PHE H    8          0        -4.82                     
CISPEP   4 PHE H    8    SER H    9          0         9.68                     
CISPEP   5 SER H  124    GLY H  125          0       -12.51                     
CISPEP   6 THR I   10    ILE I   11          0        15.71                     
CISPEP   7 GLU I   15    GLY I   16          0        -4.49                     
CISPEP   8 GLY I  125    GLY I  126          0         1.00                     
CISPEP   9 GLU J  179    ALA J  180          0       -19.93                     
CISPEP  10 ALA J  180    ILE J  181          0        -2.53                     
CISPEP  11 ILE J  181    GLU J  182          0        16.45                     
CISPEP  12 GLU J  182    THR J  183          0         0.31                     
CISPEP  13 LEU K   21    PHE K   22          0        10.05                     
CISPEP  14 GLY M    6    TYR M    7          0        19.32                     
CISPEP  15 THR B  434    PRO B  435          0        17.75                     
CISPEP  16 PRO B  435    GLU B  436          0       -16.65                     
CISPEP  17 GLU B  436    GLY B  437          0         6.18                     
CISPEP  18 TYR B  439    LEU B  440          0        -0.49                     
CISPEP  19 LYS C  393    ASP C  394          0        25.45                     
CISPEP  20 ASP D  410    GLU D  411          0        18.75                     
CISPEP  21 GLU D  411    GLN D  412          0        -3.90                     
CISPEP  22 GLN D  412    GLU D  413          0        24.09                     
CISPEP  23 LYS F  431    LYS F  432          0         9.90                     
CISPEP  24 LYS F  432    ALA F  433          0       -11.15                     
CISPEP  25 ASN F  434    LEU F  435          0        11.10                     
SITE     1 AC1  4 VAL c  53  HIS c 113  SER c 114  HIS c 115                    
SITE     1 AC2 14 GLY A 179  PRO A 218  GLY A 219  THR A 220                    
SITE     2 AC2 14 GLY A 221  LYS A 222  THR A 223  LEU A 224                    
SITE     3 AC2 14 ASP A 275  ILE A 354  ILE A 357  HIS A 358                    
SITE     4 AC2 14 GLY A 382  ALA A 383                                          
SITE     1 AC3 12 ASP B 186  GLY B 189  GLY B 229  THR B 230                    
SITE     2 AC3 12 GLY B 231  LYS B 232  THR B 233  LEU B 234                    
SITE     3 AC3 12 ASN B 332  HIS B 368  GLY B 392  ALA B 393                    
SITE     1 AC4 14 GLY D 168  PRO D 208  GLY D 211  LYS D 212                    
SITE     2 AC4 14 THR D 213  MET D 214  LYS D 217  ILE D 344                    
SITE     3 AC4 14 ILE D 348  GLY D 372  ASN D 376  ASP E 265                    
SITE     4 AC4 14 ARG E 291  ARG E 294                                          
SITE     1 AC5 11 PRO F 229  GLY F 230  LYS F 233  THR F 234                    
SITE     2 AC5 11 ASP F 286  GLU F 287  ALA F 331  ASN F 333                    
SITE     3 AC5 11 ILE F 365  GLY F 393  ALA F 394                               
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1                      
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      1.000000  0.000000  0.000000        0.00000                         
SCALE2      0.000000  1.000000  0.000000        0.00000                         
SCALE3      0.000000  0.000000  1.000000        0.00000                         
(ATOM LINES ARE NOT SHOWN.)
END                                                                             
DBGET integrated database retrieval system