GenomeNet

Database: Pfam
Entry: ADPrib_exo_Tox
LinkDB: ADPrib_exo_Tox
Original site: ADPrib_exo_Tox 
#=GF ID   ADPrib_exo_Tox
#=GF AC   PF03496.17
#=GF DE   ADP-ribosyltransferase exoenzyme
#=GF PI   Binary_toxA;
#=GF AU   Griffiths-Jones SR;0000-0001-6043-807X
#=GF SE   PRINTS
#=GF GA   23.40 21.90;
#=GF TC   23.40 22.00;
#=GF NC   23.30 21.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   AB_toxin
#=GF CL   CL0084
#=GF RN   [1]
#=GF RM   10024602
#=GF RT   Pseudomonas aeruginosa exoenzyme S is a biglutamic acid
#=GF RT   ADP-ribosyltransferase.
#=GF RA   Radke J, Pederson KJ, Barbieri JT;
#=GF RL   Infect Immun. 1999;67:1508-1510.
#=GF RN   [2]
#=GF RM   12498797
#=GF RT   Crystal structure and site-directed mutagenesis of enzymatic
#=GF RT   components from Clostridium perfringens iota-toxin.
#=GF RA   Tsuge H, Nagahama M, Nishimura H, Hisatsune J, Sakaguchi Y,
#=GF RA   Itogawa Y, Katunuma N, Sakurai J;
#=GF RL   J Mol Biol. 2003;325:471-483.
#=GF DR   INTERPRO; IPR003540;
#=GF DR   SCOP; 1giq; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of bacterial and viral bi-glutamic acid
#=GF CC   ADP-ribosyltransferases, where, in Swiss:Q93Q17, E403 is the
#=GF CC   catalytic residue and E401 contributes to the transfer of
#=GF CC   ADP-ribose to the target protein. In clostridial species it is
#=GF CC   actin that is being ADP-ribosylated; this result is lethal and
#=GF CC   dermonecrotic in infected mammals.
#=GF SQ   614
#=GS Q331X8_CBCP/55-246            AC Q331X8.1
#=GS A0A0M0K3S9_9EUKA/435-601      AC A0A0M0K3S9.1
#=GS A0A6V8KAB9_9ACTN/73-231       AC A0A6V8KAB9.1
#=GS R6T0W0_9CLOT/43-303           AC R6T0W0.1
#=GS R7HM69_9BACT/1-162            AC R7HM69.1
#=GS C3V2I2_BPR51/400-623          AC C3V2I2.1
#=GS A0A3A6TC76_9GAMM/65-268       AC A0A3A6TC76.1
#=GS A0A1I5KMZ0_9PSEU/602-770      AC A0A1I5KMZ0.1
#=GS A0A2I6UFZ5_9CAUD/380-627      AC A0A2I6UFZ5.1
#=GS A0A2R7ILB9_9SPHN/407-576      AC A0A2R7ILB9.1
#=GS S1R3D3_9ENTE/287-445          AC S1R3D3.1
#=GS A7IV29_PBCVM/316-468          AC A7IV29.1
#=GS A0A1I5GB53_9ACTN/1599-1774    AC A0A1I5GB53.1
#=GS A0A370BB51_9ACTN/768-956      AC A0A370BB51.1
#=GS A0A2T0N2E1_9ACTN/416-590      AC A0A2T0N2E1.1
#=GS A0A143FQK7_9CAUD/116-304      AC A0A143FQK7.1
#=GS U3BY13_9VIBR/39-224           AC U3BY13.1
#=GS A0A430B8J6_9ENTE/13-216       AC A0A430B8J6.1
#=GS A0A6M3SWS4_9CAUD/52-188       AC A0A6M3SWS4.1
#=GS A0A0A0Q2H0_9CAUD/380-632      AC A0A0A0Q2H0.1
#=GS M9M5M5_PAEPP/952-1215         AC M9M5M5.1
#=GS Q6U9B5_9CAUD/346-567          AC Q6U9B5.1
#=GS A0A484F3J4_9EURY/28-215       AC A0A484F3J4.1
#=GS A0A0M0K639_9EUKA/216-359      AC A0A0M0K639.1
#=GS A0A087ACS7_9BIFI/43-224       AC A0A087ACS7.1
#=GS A0A3S5C2C5_9FIRM/330-494      AC A0A3S5C2C5.1
#=GS A0A6G9Y6X2_9NOCA/2276-2433    AC A0A6G9Y6X2.1
#=GS A0A0W0R2E0_9GAMM/458-627      AC A0A0W0R2E0.1
#=GS A0A0M0JCD7_9EUKA/565-755      AC A0A0M0JCD7.1
#=GS A0A087CSG8_9BIFI/245-428      AC A0A087CSG8.1
#=GS A0A1T4QC30_9ACTN/3678-3860    AC A0A1T4QC30.1
#=GS A0A1J4KY51_9EUKA/29-233       AC A0A1J4KY51.1
#=GS D7AXP3_NOCDD/1831-1962        AC D7AXP3.1
#=GS L7TGZ4_9VIRU/1096-1307        AC L7TGZ4.1
#=GS A0A3M2KZX3_9NOCA/87-259       AC A0A3M2KZX3.1
#=GS A0A2U7NBV9_9CAUD/387-589      AC A0A2U7NBV9.1
#=GS H9L477_SALTY/372-574          AC H9L477.1
#=GS A0A6G9YR16_9NOCA/26-192       AC A0A6G9YR16.1
#=GS Q0GBT4_9CAUD/1233-1406        AC Q0GBT4.1
#=GS A0A3R7G0X8_9ACTN/585-754      AC A0A3R7G0X8.1
#=GS A0A1M6L3B3_9ACTN/7620-7745    AC A0A1M6L3B3.1
#=GS A0A0P6W9K5_9RHIZ/118-291      AC A0A0P6W9K5.1
#=GS V8GA40_9BURK/301-458          AC V8GA40.1
#=GS A0A6M3T305_9CAUD/113-300      AC A0A6M3T305.1
#=GS Q2JA84_FRACC/72-235           AC Q2JA84.1
#=GS A0A6N2HUM1_9ACTN/403-576      AC A0A6N2HUM1.1
#=GS A0A7G8AL20_9CAUD/377-629      AC A0A7G8AL20.1
#=GS A0A3Q9R9D5_9CAUD/396-535      AC A0A3Q9R9D5.1
#=GS A0A3M2KX64_9NOCA/329-490      AC A0A3M2KX64.1
#=GS A0A366M9X3_9EURY/8-107        AC A0A366M9X3.1
#=GS D9SWE1_CLOC7/284-469          AC D9SWE1.1
#=GS Q9K742_BACHD/315-485          AC Q9K742.1
#=GS A0A368SY25_9ACTN/193-381      AC A0A368SY25.1
#=GS A0A1G5LWG1_9ACTN/367-540      AC A0A1G5LWG1.1
#=GS A0A285KL18_9ACTN/278-462      AC A0A285KL18.1
#=GS A0A0N0SML8_9ACTN/728-897      AC A0A0N0SML8.1
#=GS A0A2U7NLW4_9CAUD/337-550      AC A0A2U7NLW4.1
#=GS A0A088FVX9_9CAUD/377-629      AC A0A088FVX9.1
#=GS D9I6D2_9CAUD/322-584          AC D9I6D2.1
#=GS A0A346FJS7_BPT6/361-623       AC A0A346FJS7.1
#=GS A0A6I5CF30_9ACTN/302-472      AC A0A6I5CF30.1
#=GS E7G789_9FIRM/10-182           AC E7G789.1
#=GS D7RMK2_9CAUD/379-630          AC D7RMK2.1
#=GS A0A2Z4Q6J5_9CAUD/490-654      AC A0A2Z4Q6J5.1
#=GS Q19ZG0_9CAUD/36-238           AC Q19ZG0.1
#=GS A0A2N6S7I8_9STRE/343-537      AC A0A2N6S7I8.1
#=GS A0A3A4KMT2_9NOCA/337-494      AC A0A3A4KMT2.1
#=GS A0A6M5CER5_9CAUD/335-554      AC A0A6M5CER5.1
#=GS A0A4D6T4H1_9CAUD/110-303      AC A0A4D6T4H1.1
#=GS A0A385D492_9CAUD/292-462      AC A0A385D492.1
#=GS A0A4P6YRF1_9LACO/144-311      AC A0A4P6YRF1.1
#=GS A0A482GR80_9CAUD/411-613      AC A0A482GR80.1
#=GS A0A1X1R3Z7_9MYCO/688-840      AC A0A1X1R3Z7.1
#=GS A0A142K5A4_9CAUD/111-307      AC A0A142K5A4.1
#=GS A0A0M0KB63_9EUKA/622-785      AC A0A0M0KB63.1
#=GS D3JZ65_9CAUD/4-194            AC D3JZ65.1
#=GS A0A7G8LJK1_9CAUD/1037-1217    AC A0A7G8LJK1.1
#=GS A0A2H4YGH1_9CAUD/386-632      AC A0A2H4YGH1.1
#=GS A0A482MWF7_9CAUD/377-629      AC A0A482MWF7.1
#=GS A0A482GKW0_9CAUD/81-273       AC A0A482GKW0.1
#=GS A0A327KB05_9RHIZ/494-663      AC A0A327KB05.1
#=GS A0A4D6B069_9CAUD/391-585      AC A0A4D6B069.1
#=GS A0A3N2MFB2_9BACT/7-181        AC A0A3N2MFB2.1
#=GS A0A427TZJ4_9VIBR/60-240       AC A0A427TZJ4.1
#=GS A0A6G8R0V7_9CAUD/294-461      AC A0A6G8R0V7.1
#=GS A0A4R3CDT1_9ACTN/147-335      AC A0A4R3CDT1.1
#=GS A0A1C5D904_9ACTN/215-403      AC A0A1C5D904.1
#=GS A0A6C0QX04_9BACL/56-248       AC A0A6C0QX04.1
#=GS K0YZ09_9ACTO/277-481          AC K0YZ09.1
#=GS K0ES05_9NOCA/352-495          AC K0ES05.1
#=GS A0A7D5HPV0_9CAUD/334-555      AC A0A7D5HPV0.1
#=GS A0A3Q9R9R3_9CAUD/363-627      AC A0A3Q9R9R3.1
#=GS C8PDE0_9LACO/10-178           AC C8PDE0.1
#=GS A0A484F4D4_9EURY/81-238       AC A0A484F4D4.1
#=GS A0A372JJJ8_9ACTN/1232-1370    AC A0A372JJJ8.1
#=GS A0A075R783_BRELA/308-501      AC A0A075R783.1
#=GS A0A1H7EWK5_9FIRM/185-410      AC A0A1H7EWK5.1
#=GS A0A2M9A9J4_9BACT/646-875      AC A0A2M9A9J4.1
#=GS A0A4D6B841_9CAUD/339-517      AC A0A4D6B841.1
#=GS A0A370GUK8_9NOCA/19-184       AC A0A370GUK8.1
#=GS A0A1L8TA19_9ENTE/39-224       AC A0A1L8TA19.1
#=GS A0A7G3KB81_9CAUD/378-641      AC A0A7G3KB81.1
#=GS A0A0A0YR16_9CAUD/391-632      AC A0A0A0YR16.1
#=GS Q19CI9_9CAUD/384-583          AC Q19CI9.1
#=GS A0A368SXM7_9ACTN/96-282       AC A0A368SXM7.1
#=GS A0A0M0LRA7_9EUKA/349-544      AC A0A0M0LRA7.1
#=GS A0A2V5KBT9_9BACL/365-533      AC A0A2V5KBT9.1
#=GS A0A2T0GW67_9ACTN/1-154        AC A0A2T0GW67.1
#=GS Q6U9B6_9CAUD/375-578          AC Q6U9B6.1
#=GS E7GEM6_9FIRM/31-195           AC E7GEM6.1
#=GS Q835C0_ENTFA/251-404          AC Q835C0.1
#=GS A7RAS8_PBCVA/275-413          AC A7RAS8.1
#=GS R5HI52_9SPIR/653-864          AC R5HI52.1
#=GS A0A5Q2F593_9CAUD/1085-1284    AC A0A5Q2F593.1
#=GS A8R9I2_9CAUD/393-649          AC A8R9I2.1
#=GS A0A316DZ98_9BACT/7-174        AC A0A316DZ98.1
#=GS A0A371JEH4_9FIRM/168-356      AC A0A371JEH4.1
#=GS A0A117RCR2_9ACTN/312-489      AC A0A117RCR2.1
#=GS A0A6C0QYH3_9BACL/17-164       AC A0A6C0QYH3.1
#=GS D2AT52_STRRD/733-908          AC D2AT52.1
#=GS A0A6B9J270_9CAUD/310-471      AC A0A6B9J270.1
#=GS A0KHA9_AERHH/714-902          AC A0KHA9.1
#=GS A0A372SR94_9FIRM/252-413      AC A0A372SR94.1
#=GS A9MJX0_SALAR/21-194           AC A9MJX0.1
#=GS A0A0D8HVF2_RHOSX/492-683      AC A0A0D8HVF2.1
#=GS A0A4Y8S4G7_9SPHI/42-211       AC A0A4Y8S4G7.1
#=GS A0A399FXY8_9ACTN/453-659      AC A0A399FXY8.1
#=GS A0A370H9R7_9NOCA/88-258       AC A0A370H9R7.1
#=GS A0A191TJE9_9BACT/6-186        AC A0A191TJE9.1
#=GS A0A410T5K7_9CAUD/393-614      AC A0A410T5K7.1
#=GS A0A4P6PX21_9ACTN/560-727      AC A0A4P6PX21.1
#=GS A0A7D7IQT0_9CAUD/411-613      AC A0A7D7IQT0.1
#=GS A0A2Z4GZ01_9CAUD/324-498      AC A0A2Z4GZ01.1
#=GS E3BG07_9VIBR/64-222           AC E3BG07.1
#=GS A0A1V0CNT9_9VIRU/252-456      AC A0A1V0CNT9.1
#=GS B2HNR5_MYCMM/648-801          AC B2HNR5.1
#=GS A0A286EHY0_9ACTN/526-692      AC A0A286EHY0.1
#=GS A0A0M6ZWK0_9RHOB/362-538      AC A0A0M6ZWK0.1
#=GS E5EPY8_9CAUD/395-607          AC E5EPY8.1
#=GS A7IUB5_PBCVM/387-525          AC A7IUB5.1
#=GS A0A386KR92_9CAUD/121-313      AC A0A386KR92.1
#=GS A0A0X8WQK7_9CAUD/775-959      AC A0A0X8WQK7.1
#=GS A0A6B9XWT4_9CAUD/378-641      AC A0A6B9XWT4.1
#=GS A0A6B9J089_9CAUD/1-75         AC A0A6B9J089.1
#=GS E3SF14_9CAUD/373-614          AC E3SF14.1
#=GS K0F1Z5_9NOCA/347-504          AC K0F1Z5.1
#=GS F9QEB8_9MOLU/44-278           AC F9QEB8.1
#=GS A0A3G2KFF4_9CAUD/437-663      AC A0A3G2KFF4.1
#=GS L1P601_9FLAO/4-127            AC L1P601.1
#=GS A0A0A0BVR8_9CELL/304-461      AC A0A0A0BVR8.1
#=GS F9VLA8_ARTSS/8-180            AC F9VLA8.1
#=GS A0A3S9UC48_9CAUD/108-304      AC A0A3S9UC48.1
#=GS A0A1R3UX65_9ACTN/1097-1266    AC A0A1R3UX65.1
#=GS A0A1I0R055_9FIRM/16-190       AC A0A1I0R055.1
#=GS A0A0B6VNX0_9CAUD/378-641      AC A0A0B6VNX0.1
#=GS A0A328UIT7_9FIRM/81-264       AC A0A328UIT7.1
#=GS A0A4D6AHL7_9CAUD/52-188       AC A0A4D6AHL7.1
#=GS A0A6M9Z4Z9_9CAUD/302-462      AC A0A6M9Z4Z9.1
#=GS D7AXP2_NOCDD/916-1046         AC D7AXP2.1
#=GS A0A6M5CDN3_9CAUD/361-578      AC A0A6M5CDN3.1
#=GS A0A4Y9PX28_9MICO/775-942      AC A0A4Y9PX28.1
#=GS A0A192YC21_9CAUD/374-617      AC A0A192YC21.1
#=GS A0A3A4KI44_9NOCA/85-254       AC A0A3A4KI44.1
#=GS A0A5N5RCE9_9BIFI/277-461      AC A0A5N5RCE9.1
#=GS A0A370GIJ2_9NOCA/4030-4231    AC A0A370GIJ2.1
#=GS K0EQG1_9NOCA/2674-2826        AC K0EQG1.1
#=GS A0A2I1K587_9LACT/10-162       AC A0A2I1K587.1
#=GS R7FEW3_9FIRM/82-249           AC R7FEW3.1
#=GS U2NNE6_9CLOT/26-189           AC U2NNE6.1
#=GS A0A5Q3Q4Y3_9PSEU/511-691      AC A0A5Q3Q4Y3.1
#=GS A0A2A2YV06_9ACTN/748-915      AC A0A2A2YV06.1
#=GS F3NAB8_9ACTN/608-779          AC F3NAB8.1
#=GS A0A0R1HLZ6_9LACO/142-304      AC A0A0R1HLZ6.1
#=GS A0A142HD82_9BACT/4-60         AC A0A142HD82.1
#=GS A0A1H4E5W2_9BACT/659-867      AC A0A1H4E5W2.1
#=GS A0A066YLA7_9ACTN/589-752      AC A0A066YLA7.1
#=GS C3V2I3_BPR51/377-628          AC C3V2I3.1
#=GS A0A640QDM8_9FLAO/32-232       AC A0A640QDM8.1
#=GS R5M9C1_9MOLU/286-528          AC R5M9C1.1
#=GS S4MVY8_9ACTN/643-812          AC S4MVY8.1
#=GS A0A399G1Q2_9ACTN/856-1039     AC A0A399G1Q2.1
#=GS ALT_BPT4/374-615              AC P12726.2
#=GS V6K6A4_STRNV/248-429          AC V6K6A4.1
#=GS A0A3E2N8K9_9CLOT/383-544      AC A0A3E2N8K9.1
#=GS A0A6V8KBY3_9ACTN/333-513      AC A0A6V8KBY3.1
#=GS A0A370HDL3_9NOCA/6614-6756    AC A0A370HDL3.1
#=GS Q7Y3M2_BPRB4/81-273           AC Q7Y3M2.1
#=GS A0A3G9J7M8_9BACL/382-538      AC A0A3G9J7M8.1
#=GS A0A0M0JE29_9EUKA/298-494      AC A0A0M0JE29.1
#=GS A0A2U2MVF6_9BIFI/199-383      AC A0A2U2MVF6.1
#=GS A0A4Y6EGJ9_9CAUD/536-704      AC A0A4Y6EGJ9.1
#=GS A0A1H6A395_9ACTN/441-611      AC A0A1H6A395.1
#=GS M9LQR2_PAEPP/49-223           AC M9LQR2.1
#=GS A0A484F684_9EURY/91-221       AC A0A484F684.1
#=GS A0A4D6B4G3_9CAUD/339-517      AC A0A4D6B4G3.1
#=GS A0A0M8XSE3_9ACTN/3460-3630    AC A0A0M8XSE3.1
#=GS K0ZG41_9ACTO/1-66             AC K0ZG41.1
#=GS A0A6G3SHT0_9ACTN/461-629      AC A0A6G3SHT0.1
#=GS B1BBR9_CLOBO/55-244           AC B1BBR9.1
#=GS Q6U9B4_9CAUD/111-308          AC Q6U9B4.1
#=GS A0A1M5QGY2_9FLAO/5-181        AC A0A1M5QGY2.1
#=GS Q1ZMC1_PHOAS/38-225           AC Q1ZMC1.1
#=GS F9VIT7_ARTSS/331-523          AC F9VIT7.1
#=GS V9XQC9_9NOCA/470-641          AC V9XQC9.1
#=GS EXOT_PSEAE/245-434            AC Q9I788.1
#=GS EXOT_PSEAE/245-434            DR PDB; 6GNN C; 242-431;
#=GS D7B232_NOCDD/280-397          AC D7B232.1
#=GS F9VIQ1_ARTSS/98-290           AC F9VIQ1.1
#=GS F0SXF8_SYNGF/423-597          AC F0SXF8.1
#=GS A0A3T0ILI7_9CAUD/380-628      AC A0A3T0ILI7.1
#=GS K8ERW4_CARML/152-306          AC K8ERW4.2
#=GS A0A2Z5ZD96_9CAUD/376-621      AC A0A2Z5ZD96.1
#=GS A0A2Z4Q1W4_9CAUD/89-291       AC A0A2Z4Q1W4.1
#=GS A0A6I2G041_9NOCA/16-182       AC A0A6I2G041.1
#=GS A0A1X7G432_TRICW/409-575      AC A0A1X7G432.1
#=GS A0A7D5HM57_9CAUD/319-583      AC A0A7D5HM57.1
#=GS A0A2S9Z3C5_9CORY/731-911      AC A0A2S9Z3C5.1
#=GS D7AXP3_NOCDD/100-233          AC D7AXP3.1
#=GS A0A1G5GLB1_9FIRM/2-131        AC A0A1G5GLB1.1
#=GS A0A5B9NEF3_9CAUD/412-636      AC A0A5B9NEF3.1
#=GS W0V0D4_9BURK/300-491          AC W0V0D4.1
#=GS A0A0M0KEG5_9BACI/453-633      AC A0A0M0KEG5.1
#=GS A0A060AML4_9CAUD/367-603      AC A0A060AML4.1
#=GS A0A1V0E017_9CAUD/62-256       AC A0A1V0E017.1
#=GS A0A1X2CEE4_9MYCO/677-836      AC A0A1X2CEE4.1
#=GS A0A3G9MIA9_RHOOP/586-764      AC A0A3G9MIA9.1
#=GS A0A0W0XX95_9GAMM/104-290      AC A0A0W0XX95.1
#=GS A0A2H4YFM2_9CAUD/254-489      AC A0A2H4YFM2.1
#=GS N9WWI0_CLOIN/246-452          AC N9WWI0.1
#=GS A0A1Q4Y804_9ACTN/546-718      AC A0A1Q4Y804.1
#=GS E5EYX3_9CAUD/349-554          AC E5EYX3.1
#=GS A0A6F8Y916_9ACTN/428-588      AC A0A6F8Y916.1
#=GS A0A345AV36_9CAUD/408-625      AC A0A345AV36.1
#=GS A0A133ZBC2_9CORY/309-513      AC A0A133ZBC2.1
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