#=GF ID   Arf
#=GF AC   PF00025.25
#=GF DE   ADP-ribosylation factor family
#=GF PI   arf;
#=GF AU   Sonnhammer ELL;0000-0002-9015-5588
#=GF SE   Swissprot
#=GF GA   22.30 22.30;
#=GF TC   22.30 22.30;
#=GF NC   22.20 22.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Domain
#=GF WK   ADP_ribosylation_factor
#=GF CL   CL0023
#=GF RC   3D Structure reference.
#=GF RN   [1]
#=GF RM   7990966
#=GF RT   Structure of the human ADP-ribosylation factor 1 complexed with
#=GF RT   GDP. 
#=GF RA   Amor JC, Harrison DH, Kahn RA, Ringe D; 
#=GF RL   Nature 1994;372:704-708.
#=GF RC   Mini review.
#=GF RN   [2]
#=GF RM   7759471
#=GF RT   Structure and function of ARF proteins: Activators of cholera
#=GF RT   toxin and critical components of intracellular vesicular
#=GF RT   transport processes. 
#=GF RA   Moss J, Vaughan M; 
#=GF RL   J. Biol. Chem. 1995;270:12327-12330.
#=GF RN   [3]
#=GF RM   7770914
#=GF RT   Arf proteins: the membrane traffic police? 
#=GF RA   Boman AL, Kahn RA; 
#=GF RL   Trends Biochem Sci 1995;20:147-150.
#=GF RN   [4]
#=GF RM   1899243
#=GF RT   Human ADP-ribosylation factors. A functionally conserved family
#=GF RT   of GTP-binding proteins. 
#=GF RA   Kahn RA, Kern FG, Clark J, Gelmann EP, Rulka C; 
#=GF RL   J Biol Chem 1991;266:2606-2614.
#=GF DR   INTERPRO; IPR006689;
#=GF DR   PROSITE; PDOC00781;
#=GF DR   PROSITE; PDOC00017;
#=GF DR   SCOP; 1hur; fa;
#=GF DR   SMART; ARF;
#=GF DR   PRINTS; PR00328;
#=GF DC   The prints entry specific to Sar1 proteins
#=GF DR   PROSITE; PDOC01020;
#=GF DC   The Prosite entry specific to Sar1 proteins
#=GF DR   HOMSTRAD; gtp;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Pfam combines a number of different Prosite families together
#=GF SQ   42961
#=GS A0A8H7U225_9APHY/5-177      AC A0A8H7U225.1
#=GS T1H8C7_RHOPR/8-181          AC T1H8C7.1
#=GS A0A6P6QLS6_CARAU/3-177      AC A0A6P6QLS6.1
#=GS A0A179U5F4_AJEDR/7-182      AC A0A179U5F4.1
#=GS A0A5F5PUL8_HORSE/2-131      AC A0A5F5PUL8.1
#=GS A0A8J4NQH1_EUDCH/1-122      AC A0A8J4NQH1.1
#=GS A0A8E0RMX1_9TREM/5-183      AC A0A8E0RMX1.1
#=GS A0A7K8YKF0_9PASS/1-179      AC A0A7K8YKF0.1
#=GS A0A4W2DQ75_BOBOX/69-229     AC A0A4W2DQ75.1
#=GS A0A196SK19_BLAHN/3-178      AC A0A196SK19.1
#=GS A0A0A2KYE9_PENIT/5-178      AC A0A0A2KYE9.1
#=GS A0A1S3FSU5_DIPOR/1-165      AC A0A1S3FSU5.1
#=GS K4AG80_SETIT/5-153          AC K4AG80.1
#=GS A0A6A1VR37_9ROSI/141-309    AC A0A6A1VR37.1
#=GS R7VBW7_CAPTE/1-172          AC R7VBW7.1
#=GS F0X9G0_GROCL/72-213         AC F0X9G0.1
#=GS E9HDF7_DAPPU/5-177          AC E9HDF7.1
#=GS A0A1S3FU23_DIPOR/4-181      AC A0A1S3FU23.1
#=GS A0A091FVC4_9AVES/1-161      AC A0A091FVC4.1
#=GS A0A2S5BG18_9BASI/1-49       AC A0A2S5BG18.1
#=GS A0A674J580_TERCA/8-181      AC A0A674J580.1
#=GS A0A024X315_PLAFC/17-202     AC A0A024X315.1
#=GS A0A1X6PED4_PORUM/5-188      AC A0A1X6PED4.1
#=GS H6CB62_EXODN/1-170          AC H6CB62.1
#=GS A0A1J6KCQ8_NICAT/5-177      AC A0A1J6KCQ8.1
#=GS A0A7N5JY22_AILME/3-176      AC A0A7N5JY22.1
#=GS A0A2S7PP20_9HELO/83-229     AC A0A2S7PP20.1
#=GS A0A7L1IKY7_SMUAF/2-175      AC A0A7L1IKY7.1
#=GS A0A484C4V6_PERFV/1-173      AC A0A484C4V6.1
#=GS A0A7J0E415_9ERIC/5-100      AC A0A7J0E415.1
#=GS A0A4U0X3R1_9PEZI/117-207    AC A0A4U0X3R1.1
#=GS A0A6P6IN98_PUMCO/73-216     AC A0A6P6IN98.1
#=GS A0A3M7SSI2_BRAPC/7-192      AC A0A3M7SSI2.1
#=GS A0A7L2DYA4_ANTMN/12-197     AC A0A7L2DYA4.1
#=GS A0A1J9PC07_9EURO/5-177      AC A0A1J9PC07.1
#=GS A0A8J4WJ95_9TREM/6-182      AC A0A8J4WJ95.1
#=GS A0A2P7YUP7_9ASCO/74-238     AC A0A2P7YUP7.1
#=GS W5PP36_SHEEP/3-176          AC W5PP36.1
#=GS A0A093FG99_TYTAL/313-487    AC A0A093FG99.1
#=GS A0A8C5SMR8_LATLA/8-190      AC A0A8C5SMR8.1
#=GS A0A287CZS3_ICTTR/1-167      AC A0A287CZS3.1
#=GS A0A7L2HY76_SAGSE/1-90       AC A0A7L2HY76.1
#=GS A0A5J4NQQ8_9TREM/5-181      AC A0A5J4NQQ8.1
#=GS A0A427YIT4_9TREE/8-184      AC A0A427YIT4.1
#=GS A0A6J1YCJ0_ACIJB/4-93       AC A0A6J1YCJ0.1
#=GS L5L725_PTEAL/41-181         AC L5L725.1
#=GS A0A811N252_9POAL/5-190      AC A0A811N252.1
#=GS A0A7L3A9X0_9PASE/8-190      AC A0A7L3A9X0.1
#=GS A7E5H0_SCLS1/5-177          AC A7E5H0.1
#=GS A0A7K4T2K4_9CHAR/3-176      AC A0A7K4T2K4.1
#=GS A0A4Y7JDE7_PAPSO/5-92       AC A0A4Y7JDE7.1
#=GS A0A811XX75_NYCPR/3-176      AC A0A811XX75.1
#=GS A0A8C8YYP2_PROSS/12-109     AC A0A8C8YYP2.1
#=GS A0A7K9RQP8_9PASS/1-169      AC A0A7K9RQP8.1
#=GS A0A6H5GQJ9_9HEMI/7-192      AC A0A6H5GQJ9.1
#=GS A0A2U3X4W1_ODORO/5-177      AC A0A2U3X4W1.1
#=GS A0A851QK12_ANHAN/1-173      AC A0A851QK12.1
#=GS A0A2Z6REZ1_9GLOM/5-177      AC A0A2Z6REZ1.1
#=GS A0A0V0X9P3_9BILA/32-204     AC A0A0V0X9P3.1
#=GS A0A2I3GLM6_NOMLE/6-150      AC A0A2I3GLM6.1
#=GS A0A1S3ER73_DIPOR/5-177      AC A0A1S3ER73.1
#=GS A0A5J5MVC1_MUNRE/4-187      AC A0A5J5MVC1.1
#=GS A0A7J7XDQ7_MYOMY/71-227     AC A0A7J7XDQ7.1
#=GS A0A3M6VRM5_9STRA/1-157      AC A0A3M6VRM5.1
#=GS A0A1U8AL21_NELNU/7-192      AC A0A1U8AL21.1
#=GS K0KUR2_WICCF/202-385        AC K0KUR2.1
#=GS A0A8H6A0J0_ASPBU/1-166      AC A0A8H6A0J0.1
#=GS A0A3P8RYP2_AMPPE/85-153     AC A0A3P8RYP2.1
#=GS A0A1U8FHZ9_CAPAN/7-180      AC A0A1U8FHZ9.1
#=GS A0A103YLT0_CYNCS/4-67       AC A0A103YLT0.1
#=GS A0A8J5MQZ5_HOMAM/4-176      AC A0A8J5MQZ5.1
#=GS A0A3Q1MH25_BOVIN/8-176      AC A0A3Q1MH25.1
#=GS A0A673VML3_SURSU/4-170      AC A0A673VML3.1
#=GS A0A7K6D2Z5_9PASS/5-74       AC A0A7K6D2Z5.1
#=GS A0A8C8R7R9_9SAUR/4-187      AC A0A8C8R7R9.1
#=GS A0A087Y5Q1_POEFO/5-177      AC A0A087Y5Q1.1
#=GS A0A091V2J1_NIPNI/1-163      AC A0A091V2J1.1
#=GS A0A3Q1H7L6_ANATE/1-173      AC A0A3Q1H7L6.2
#=GS W9YDH8_9EURO/5-175          AC W9YDH8.1
#=GS A0A812ZHD3_9DINO/8-216      AC A0A812ZHD3.1
#=GS F8PPV6_SERL3/3-176          AC F8PPV6.1
#=GS A0A8C5H616_9TELE/5-164      AC A0A8C5H616.1
#=GS A0A0V1I2F6_9BILA/404-576    AC A0A0V1I2F6.1
#=GS A0A151K3K2_9HYME/4-93       AC A0A151K3K2.1
#=GS A0A6P5CRC4_BOSIN/5-176      AC A0A6P5CRC4.1
#=GS ARFJ_DICDI/12-185           AC Q54V47.1
#=GS A0A267DM42_9PLAT/14-187     AC A0A267DM42.1
#=GS A0A498S079_ACAVI/3-124      AC A0A498S079.1
#=GS A0A7K7T0J2_9TYRA/5-74       AC A0A7K7T0J2.1
#=GS A0A843UJE0_COLES/4-67       AC A0A843UJE0.1
#=GS A0A7J6W2C4_THATH/4-177      AC A0A7J6W2C4.1
#=GS A0A5M3Z0E5_ASPTE/4-115      AC A0A5M3Z0E5.1
#=GS A0A151PE62_ALLMI/87-259     AC A0A151PE62.1
#=GS A0A8X9A289_SALSN/5-184      AC A0A8X9A289.1
#=GS A0A2K6QRE6_RHIRO/75-242     AC A0A2K6QRE6.1
#=GS A0A7K9LP33_9PASS/2-140      AC A0A7K9LP33.1
#=GS A0A158R1C6_NIPBR/63-215     AC A0A158R1C6.1
#=GS A0A671KQU7_9TELE/4-180      AC A0A671KQU7.1
#=GS A0A7L0F4G3_CORCN/1-161      AC A0A7L0F4G3.1
#=GS D0N4A1_PHYIT/3-178          AC D0N4A1.1
#=GS A0A4Y7I4E8_PAPSO/5-64       AC A0A4Y7I4E8.1
#=GS S9YR66_CAMFR/1-116          AC S9YR66.1
#=GS A0A0V1NI70_9BILA/388-555    AC A0A0V1NI70.1
#=GS A0A091KI48_9GRUI/2-176      AC A0A091KI48.1
#=GS A0A7L3NC93_9AVES/8-158      AC A0A7L3NC93.1
#=GS A0A2R6NTT2_9APHY/5-140      AC A0A2R6NTT2.1
#=GS A0A2Y9T0N0_PHYMC/80-252     AC A0A2Y9T0N0.1
#=GS A0A2C5Y7K4_9HYPO/1-174      AC A0A2C5Y7K4.1
#=GS A0A5D2YBY1_GOSMU/7-192      AC A0A5D2YBY1.1
#=GS A0A5E8B8W9_9ASCO/5-177      AC A0A5E8B8W9.1
#=GS A0A5A7V5J4_CUCME/5-55       AC A0A5A7V5J4.1
#=GS A0A7L0QKM0_SETKR/4-177      AC A0A7L0QKM0.1
#=GS A0A8C3YU58_9CETA/8-150      AC A0A8C3YU58.1
#=GS G3PWZ3_GASAC/6-180          AC G3PWZ3.1
#=GS A0A7L0RQT8_GLABR/1-80       AC A0A7L0RQT8.1
#=GS D3B9Z5_POLPP/5-176          AC D3B9Z5.1
#=GS A0A8H3J4Z8_9LECA/5-177      AC A0A8H3J4Z8.1
#=GS A0A2U1NYG3_ARTAN/5-79       AC A0A2U1NYG3.1
#=GS B4FMJ0_MAIZE/5-177          AC B4FMJ0.1
#=GS A0A803TEJ8_ANOCA/5-177      AC A0A803TEJ8.1
#=GS A0A8K0MGR4_9ROSA/4-178      AC A0A8K0MGR4.1
#=GS A0A176VJ02_MARPO/332-415    AC A0A176VJ02.1
#=GS A0A670I0M6_PODMU/34-154     AC A0A670I0M6.1
#=GS A0A673I3H9_9TELE/27-201     AC A0A673I3H9.1
#=GS A0A851PD97_9GALL/5-74       AC A0A851PD97.1
#=GS V7BGU9_PHAVU/5-177          AC V7BGU9.1
#=GS A0A7L3E3R1_9PASS/8-186      AC A0A7L3E3R1.1
#=GS L8H3G5_ACACA/1-175          AC L8H3G5.1
#=GS A0A5N3W2S8_MUNRE/4-168      AC A0A5N3W2S8.1
#=GS A0A8C6YD60_NAJNA/5-177      AC A0A8C6YD60.1
#=GS R0FQH7_9BRAS/7-180          AC R0FQH7.1
#=GS A0A852IKN3_9PICI/1-179      AC A0A852IKN3.1
#=GS A0A1I7W5N9_LOALO/5-177      AC A0A1I7W5N9.1
#=GS A0A7M7NFJ4_STRPU/15-200     AC A0A7M7NFJ4.1
#=GS A0A3P8VNC5_CYNSE/11-187     AC A0A3P8VNC5.1
#=GS A0A4X2KQB3_VOMUR/4-177      AC A0A4X2KQB3.1
#=GS A0A261Y5B4_9FUNG/5-181      AC A0A261Y5B4.1
#=GS A0A024TB06_9STRA/3-176      AC A0A024TB06.1
#=GS S7WAU2_SPRLO/13-185         AC S7WAU2.1
#=GS A0A4V5NBA0_9PEZI/27-134     AC A0A4V5NBA0.1
#=GS A0A0B2R6J8_GLYSO/5-177      AC A0A0B2R6J8.1
#=GS A0A392R478_9FABA/3-58       AC A0A392R478.1
#=GS A0A183JCJ2_9TREM/7-178      AC A0A183JCJ2.1
#=GS A0A2K5N8X6_CERAT/8-148      AC A0A2K5N8X6.1
#=GS A0A8B7BV75_PHODC/5-177      AC A0A8B7BV75.1
#=GS C1GQI7_PARBA/7-189          AC C1GQI7.1
#=GS I3J5Z7_ORENI/12-188         AC I3J5Z7.1
#=GS A0A813NP71_9BILA/5-177      AC A0A813NP71.1
#=GS A0A834ZGH7_9MAGN/73-139     AC A0A834ZGH7.1
#=GS A0A833RUP1_9HYME/8-181      AC A0A833RUP1.1
#=GS A0A8C9CLN5_PHOSS/5-177      AC A0A8C9CLN5.1
#=GS A0A0D9VQU4_9ORYZ/7-180      AC A0A0D9VQU4.1
#=GS A0A8J0U9S8_XENLA/16-182     AC A0A8J0U9S8.1
#=GS A0A672ZGG8_9TELE/1-177      AC A0A672ZGG8.1
#=GS A0A7J7VX09_MYOMY/107-248    AC A0A7J7VX09.1
#=GS A0A5C3DSF1_9BASI/3-179      AC A0A5C3DSF1.1
#=GS A0A672GG47_SALFA/397-571    AC A0A672GG47.1
#=GS A0A4Q4SXU5_9PEZI/1-174      AC A0A4Q4SXU5.1
#=GS A0A7N8Y9P8_9TELE/5-165      AC A0A7N8Y9P8.1
#=GS A0A5J4KD37_9CHLR/1-193      AC A0A5J4KD37.1
#=GS A0A2U3ZG63_ODORO/49-140     AC A0A2U3ZG63.1
#=GS ARF6_CHICK/1-173            AC P26990.3
#=GS A0A226PQ00_COLVI/61-204     AC A0A226PQ00.1
#=GS A0A8P0P0T6_CANLF/256-323    AC A0A8P0P0T6.1
#=GS A0A226M8A7_COLVI/4-62       AC A0A226M8A7.1
#=GS A0A8J5D9D5_9CHEL/146-264    AC A0A8J5D9D5.1
#=GS A0A8H5BVX5_9AGAR/7-189      AC A0A8H5BVX5.1
#=GS A0A3Q2IE61_HORSE/5-177      AC A0A3Q2IE61.1
#=GS Q29F85_DROPS/4-176          AC Q29F85.1
#=GS A0A851KKL2_VIDCH/2-166      AC A0A851KKL2.1
#=GS A0A232F8S4_9HYME/8-181      AC A0A232F8S4.1
#=GS A0A7I4D9X7_PHYPA/1-167      AC A0A7I4D9X7.1
#=GS Q9U0T6_LEIMA/5-186          AC Q9U0T6.1
#=GS SAR1_PICST/7-190            AC A3LTA2.1
#=GS D7G8D7_ECTSI/5-179          AC D7G8D7.1
#=GS A0A8J7P5I0_ATRSP/5-192      AC A0A8J7P5I0.1
#=GS A0A8C8LPP3_ONCTS/9-186      AC A0A8C8LPP3.1
#=GS M2N1L1_BAUPA/4-177          AC M2N1L1.1
#=GS A0A1V4KUE1_PATFA/5-164      AC A0A1V4KUE1.1
#=GS A0A067H577_CITSI/1-105      AC A0A067H577.1
#=GS A0A183LC73_9TREM/1-173      AC A0A183LC73.1
#=GS A0A087QQ70_APTFO/1-161      AC A0A087QQ70.1
#=GS A0A851PV39_ANHAN/1-58       AC A0A851PV39.1
#=GS A0A821F6R6_9BILA/1-136      AC A0A821F6R6.1
#=GS A0A7L2D5N0_CATFU/4-181      AC A0A7L2D5N0.1
#=GS A0A8H6PD30_9EURO/147-237    AC A0A8H6PD30.1
#=GS A0A6I8P9W9_ORNAN/2-173      AC A0A6I8P9W9.1
#=GS A0A8B9Z6J8_9AVES/66-141     AC A0A8B9Z6J8.1
#=GS A0A7K6RTZ5_9GRUI/8-186      AC A0A7K6RTZ5.1
#=GS A0A2K6T6N0_SAIBB/5-177      AC A0A2K6T6N0.1
#=GS A0A813MF24_ADIRI/4-176      AC A0A813MF24.1
#=GS A0A8C3D309_CAIMO/129-302    AC A0A8C3D309.1
#=GS A0A8H4NHH0_9HYPO/7-186      AC A0A8H4NHH0.1
#=GS A0A8B9NFY7_9AVES/1-173      AC A0A8B9NFY7.1
#=GS A0A8C5TK27_9PASS/5-177      AC A0A8C5TK27.1
#=GS A0A8D2Q1G5_VARKO/5-177      AC A0A8D2Q1G5.1
#=GS A0A8C6P236_NOTFU/8-148      AC A0A8C6P236.1
#=GS A0A0P1AAI3_PLAHL/5-183      AC A0A0P1AAI3.1
#=GS A0A0A0B1X2_CHAVO/1-165      AC A0A0A0B1X2.1
#=GS A0A8C7BP51_NEOVI/149-285    AC A0A8C7BP51.1
#=GS A0A2C9WKS0_MANES/3-177      AC A0A2C9WKS0.1
#=GS A0A8H8JM58_9AGAM/4-176      AC A0A8H8JM58.1
#=GS A0A8R1TTY1_ONCVO/5-177      AC A0A8R1TTY1.1
#=GS Q9VPP8_DROME/72-193         AC Q9VPP8.1
#=GS A0A2K6V5K7_SAIBB/47-213     AC A0A2K6V5K7.1
#=GS A0A667XPF1_9TELE/4-176      AC A0A667XPF1.1
#=GS A0A836B7D6_9CHLO/6-184      AC A0A836B7D6.1
#=GS A0A0E0A459_9ORYZ/1-177      AC A0A0E0A459.1
#=GS A0A3P9CTT3_9CICH/3-168      AC A0A3P9CTT3.1
#=GS A0A267F324_9PLAT/386-560    AC A0A267F324.1
#=GS A0A7J8IBA3_MOLMO/1-129      AC A0A7J8IBA3.1
#=GS A0A4U1FNP8_MONMO/1-117      AC A0A4U1FNP8.1
#=GS A0A3Q2H2U2_HORSE/471-645    AC A0A3Q2H2U2.1
#=GS A0A5F7ZYN6_MACMU/4-181      AC A0A5F7ZYN6.1
#=GS A0A444V6S5_ACIRT/59-159     AC A0A444V6S5.1
#=GS A0A834G514_RHOSS/135-269    AC A0A834G514.1
#=GS A0A7R8AIE1_9EURO/168-258    AC A0A7R8AIE1.1
#=GS H2MVS3_ORYLA/8-134          AC H2MVS3.2
#=GS A0A3B5KBC1_TAKRU/1-63       AC A0A3B5KBC1.1
#=GS A0A6P5LAN6_PHACI/28-194     AC A0A6P5LAN6.1
#=GS A0A3B5KDV4_TAKRU/5-177      AC A0A3B5KDV4.1
#=GS A0A6J2N379_9CHIR/8-181      AC A0A6J2N379.1
#=GS A0A7L3FMH9_9GRUI/8-189      AC A0A7L3FMH9.1
#=GS A0A7L1V610_SITEU/4-181      AC A0A7L1V610.1
#=GS A0A7L3F7E4_9GRUI/2-176      AC A0A7L3F7E4.1
#=GS A0A445D6V1_ARAHY/3-192      AC A0A445D6V1.1
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#=G