#=GF ID BIg21
#=GF AC PF05688.18
#=GF DE Bacterial Immunoglobulin-like 21
#=GF PI DUF824;
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF AU Moxon SJ;0000-0003-4644-1816
#=GF SE Pfam-B_2973 (release 8.0)
#=GF GA 27.40 27.40;
#=GF TC 27.40 37.70;
#=GF NC 27.20 26.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 8 -E 1000 -Z 90746521 HMM pfamseq
#=GF TP Domain
#=GF CL CL0159
#=GF RN [1]
#=GF RM 28370712
#=GF RT Structure of the Y. pseudotuberculosis adhesin InvasinE.
#=GF RA Sadana P, Monnich M, Unverzagt C, Scrima A;
#=GF RL Protein Sci. 2017;26:1182-1195.
#=GF DR INTERPRO; IPR008542;
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This entry represents BIg21(Bacterial Immunoglobulin-like 21)
#=GF CC found in InvasinE (InvE). Invasins are members of the inverse
#=GF CC autotransporter (IAT) family also referred to as type Ve
#=GF CC secretion system. In general, they consist of an N-terminal
#=GF CC beta-barrel-like domain, which is responsible for attachment of
#=GF CC invasin to the outer membrane region of bacteria, repetitive
#=GF CC Immunoglobuli-like (Ig) domains, which vary significantly in
#=GF CC number among all the invasins, and the C-terminal
#=GF CC domain/adhesion domain (AD) Pfam:PF05689, which provides
#=GF CC invasins with the specificity to bind to its host target
#=GF CC molecules. The overall structure of InvE shows that it comprises
#=GF CC of three domain architecture in which the domains BIg20
#=GF CC (Bacterial Immunoglobulin-like 20) and BIg21 adopt two layer
#=GF CC beta-sandwich fold resembling eukaryotic members of
#=GF CC Immunoglobulin-superfamily (IgSF), while the AD is a globular,
#=GF CC alpha/beta-domain. The structure of BIg21 belongs to the I2 set
#=GF CC of IgSF with a unique modification in the C-E interstrand loop,
#=GF CC important for its interaction with AD. BIg21 and AD form a
#=GF CC functional super-domain as well, necessary to target the host
#=GF CC receptor [1].
#=GF SQ 78
#=GS A0A0H2Z1J0_ECOK1/740-852 AC A0A0H2Z1J0.1
#=GS A0A077PL44_XENBV/761-856 AC A0A077PL44.1
#=GS A0A0H2Z1J0_ECOK1/474-584 AC A0A0H2Z1J0.1
#=GS A0A0H3EM56_ECO8N/1875-1987 AC A0A0H3EM56.1
#=GS A0A4Z0KA17_SALET/1-57 AC A0A4Z0KA17.1
#=GS D3VIN8_XENNA/775-870 AC D3VIN8.1
#=GS A0A4R1NDL5_9GAMM/1012-1106 AC A0A4R1NDL5.1
#=GS A0A0H2VBV9_ECOL6/214-316 AC A0A0H2VBV9.1
#=GS Q8ZN55_SALTY/1596-1725 AC Q8ZN55.1
#=GS Q8ZN56_SALTY/489-598 AC Q8ZN56.1
#=GS A0A2X4UST9_9GAMM/750-862 AC A0A2X4UST9.1
#=GS A0A0H2VBV9_ECOL6/474-584 AC A0A0H2VBV9.1
#=GS W1J0I8_9GAMM/1704-1811 AC W1J0I8.1
#=GS Q8ZN55_SALTY/1025-1138 AC Q8ZN55.1
#=GS A0A3D9U9H4_9GAMM/760-855 AC A0A3D9U9H4.1
#=GS A0A2X4UST9_9GAMM/221-323 AC A0A2X4UST9.1
#=GS B7MHZ1_ECO45/740-852 AC B7MHZ1.1
#=GS B7MHZ1_ECO45/1875-1987 AC B7MHZ1.1
#=GS A0A0H2VBV9_ECOL6/2437-2551 AC A0A0H2VBV9.1
#=GS Q8ZN55_SALTY/748-857 AC Q8ZN55.1
#=GS A0A4Z0MG49_SALET/39-158 AC A0A4Z0MG49.1
#=GS B7UGU8_ECO27/210-313 AC B7UGU8.1
#=GS A0A4Z0KGP0_SALET/1-82 AC A0A4Z0KGP0.1
#=GS W1IZ47_9GAMM/380-485 AC W1IZ47.1
#=GS A0A0H2Z1J0_ECOK1/1875-1987 AC A0A0H2Z1J0.1
#=GS A0A0H3EM56_ECO8N/740-852 AC A0A0H3EM56.1
#=GS A0A2X4UST9_9GAMM/1029-1145 AC A0A2X4UST9.1
#=GS A0A0H3EM56_ECO8N/214-316 AC A0A0H3EM56.1
#=GS A0A2X4UST9_9GAMM/1318-1432 AC A0A2X4UST9.1
#=GS A0A0H3EM56_ECO8N/474-584 AC A0A0H3EM56.1
#=GS Q8ZN55_SALTY/224-327 AC Q8ZN55.1
#=GS A0A0H2VBV9_ECOL6/2160-2273 AC A0A0H2VBV9.1
#=GS A0A0H3EM56_ECO8N/2160-2273 AC A0A0H3EM56.1
#=GS A0A4Z0L7R2_SALET/163-270 AC A0A4Z0L7R2.1
#=GS A0A0H2Z1J0_ECOK1/1019-1134 AC A0A0H2Z1J0.1
#=GS Q8ZN56_SALTY/1312-1418 AC Q8ZN56.1
#=GS A0A0H2VBV9_ECOL6/1594-1702 AC A0A0H2VBV9.1
#=GS A0A2D0KTV7_9GAMM/776-871 AC A0A2D0KTV7.1
#=GS B7MHZ1_ECO45/214-316 AC B7MHZ1.1
#=GS Q8ZN56_SALTY/2177-2296 AC Q8ZN56.1
#=GS A0A0H2VBV9_ECOL6/740-852 AC A0A0H2VBV9.1
#=GS B7MHZ1_ECO45/1019-1134 AC B7MHZ1.1
#=GS A0A0H2Z1J0_ECOK1/2160-2273 AC A0A0H2Z1J0.1
#=GS A0A4Z0PRR7_SALET/1-57 AC A0A4Z0PRR7.1
#=GS A0A1I0AU25_9GAMM/452-549 AC A0A1I0AU25.1
#=GS Q8ZN56_SALTY/1034-1144 AC Q8ZN56.1
#=GS A0A0H2VBV9_ECOL6/1307-1418 AC A0A0H2VBV9.1
#=GS B7MHZ1_ECO45/1594-1702 AC B7MHZ1.1
#=GS A0A0H2Z1J0_ECOK1/2437-2551 AC A0A0H2Z1J0.1
#=GS B7MHZ1_ECO45/2160-2273 AC B7MHZ1.1
#=GS A0A0H2Z1J0_ECOK1/214-316 AC A0A0H2Z1J0.1
#=GS Q8ZN56_SALTY/1605-1720 AC Q8ZN56.1
#=GS A0A077P4B5_XENBV/1304-1408 AC A0A077P4B5.1
#=GS Q8ZN56_SALTY/1892-2008 AC Q8ZN56.1
#=GS Q8ZN56_SALTY/220-323 AC Q8ZN56.1
#=GS A0A4Z0KBT4_SALET/14-117 AC A0A4Z0KBT4.1
#=GS A0A2X4UST9_9GAMM/481-591 AC A0A2X4UST9.1
#=GS A0A0H2Z1J0_ECOK1/1307-1418 AC A0A0H2Z1J0.1
#=GS Q8ZN56_SALTY/754-866 AC Q8ZN56.1
#=GS W1IWM1_9GAMM/760-855 AC W1IWM1.1
#=GS A0A2X4UST9_9GAMM/1603-1717 AC A0A2X4UST9.1
#=GS A0A0H3EM56_ECO8N/1019-1134 AC A0A0H3EM56.1
#=GS A0A0H3EM56_ECO8N/2437-2551 AC A0A0H3EM56.1
#=GS A0A0H2VBV9_ECOL6/1019-1134 AC A0A0H2VBV9.1
#=GS Q8ZN55_SALTY/484-594 AC Q8ZN55.1
#=GS A0A0H3EM56_ECO8N/1594-1702 AC A0A0H3EM56.1
#=GS B7MHZ1_ECO45/2437-2551 AC B7MHZ1.1
#=GS A0A0H2Z1J0_ECOK1/1594-1702 AC A0A0H2Z1J0.1
#=GS B7MHZ1_ECO45/474-584 AC B7MHZ1.1
#=GS A0A845SI55_9GAMM/789-884 AC A0A845SI55.1
#=GS B7MHZ1_ECO45/1307-1418 AC B7MHZ1.1
#=GS W1J0T3_9GAMM/1688-1793 AC W1J0T3.1
#=GS A0A6H2FA16_9ENTR/670-781 AC A0A6H2FA16.1
#=GS A0A2I0FS34_9GAMM/1692-1790 AC A0A2I0FS34.1
#=GS Q8ZN55_SALTY/1315-1428 AC Q8ZN55.1
#=GS A0A4Z0PGN6_SALET/33-121 AC A0A4Z0PGN6.1
#=GS A0A0H2VBV9_ECOL6/1875-1987 AC A0A0H2VBV9.1
#=GS A0A0H3EM56_ECO8N/1307-1418 AC A0A0H3EM56.1
A0A0H2Z1J0_ECOK1/740-852 .......GDTITMTVRTFnALNNA.PVPYTAFTITK.DMGKNRQGQTTG.............FDDPTRGAIE...MNGTLYGTSQPs.......lVYAGTTDAQGFATVEIKQ.SQGVGLSTPLNIVP.VNSYIPN.tVNYNVIFTT-l....
A0A077PL44_XENBV/761-856 ......s-NAITLTVKTF.-KHGQ.PVRNVAVEVQA.TQAINRQN----.............--KPQTITVL...IGGKPA-----.........LYQGVTDEQGVLSIPVTD.PNGNGVKTSLKITA.YGSAKP-..KTQDLIFTV-p....
A0A0H2Z1J0_ECOK1/474-584 ...geea--SLRLTITDS.KNNDQ.PLAYYYFSLHL.DDGINRKNQTDA.............AWETHPVQID...GGSNVRKVDAH.........TYEGSTDANGEATLTLTQ.PGGVGVKTHITARM.RSDFTAS..DEKDVIFTVI.....
A0A0H3EM56_ECO8N/1875-1987 ......g-TAIRMTVIVR.DSGGN.LLPGANFNLIR.GTALDRAKNRLD.............-STYDDLTIV...PVTPAGVNMSLyn....ngaQALLTTGSDGKATFDVTQ.NETYGLATPLTATL.MRDTTKS..ATMDVIFTVI.....
A0A4Z0KA17_SALET/1-57 ..psare-----------.-----.-----------.------------.............----------...--------KTK.........NRSGVSGDDGKLRFTLNQ.DKSLGLRTSITATL.SELAGET..ASVDAIFTV-p....
D3VIN8_XENNA/775-870 .......GESITLTIKTL.-NHGK.AVRNVAVRVNA.IKALNRQN----.............--VSESPTVL...LNGQSG-----.........IYQDFTDKQGMLSVVITD.PNGLGVKTTLSVTA.DRTAAP-..QTQDVIFTVV.....
A0A4R1NDL5_9GAMM/1012-1106 .......GEQIMLTVKTM.LEDGS.PAGDVIVDIHS.IGAVNRQN----.............--RSESATLL...IDGAQK-----.........-YEGSVTATGQISIPITD.PTGKGVKTTIEVTA.RNGK--T..VTKDVIFTVA.....
A0A0H2VBV9_ECOL6/214-316 .......GGSITLTVTTK.DCVGN.VVGNIPFVIKR.KDAENRQG----.............-VVNNTAPVK...LGTTELTTTAT.........EYRGTTDANGVATVTVTQ.ANGPGVKTPLVASL.AGIAQA-..SETAVIFTVL.....
Q8ZN55_SALTY/1596-1725 .......GETIPMTVTVT.NDAGQ.PQAGVAVLLTR.DYAYSRGAVDKQyiepgvigepvpfTTSPANMMLA...PVAPAGTAVAFnnqn.glstKWSGFTGDDGKLRFTLTQ.DKSLGLKTSVTAAL.ANQFDEA..ASVDAIFTV-q....
Q8ZN56_SALTY/489-598 .......GEEINMKITVT.DSATNkPLPYRYFNVYL.GDEQNRQNQKNAdid......sghqWTDDPVIITN...LEGSDG-----.........HYHGVTDANGQFSLVLTQ.DKGAGVLTPVRVVLfDGT---E..ATQNVIFTVV.....
A0A2X4UST9_9GAMM/750-862 .......GESITMTVHTVnAINGS.PVPYAAFTITK.GASRNREGMVTG.............FTDPTNGALE...MNGVLFGASQAs.......mVYSGTTNAQGVATVVIKQ.PQGVGLETPLAIAP.ASSSIPN.tVNYSVIFTA-l....
A0A0H2VBV9_ECOL6/474-584 ...geea--SLRLTITDS.KNNDQ.PLAYYYFSLHL.DDGINRKNQTDA.............AWETHPVQID...GGSNVRKVDAH.........TYEGITDANGEATLTLTQ.PGGVGVKTHITARM.RSDFTAS..DEKDVIFTVI.....
W1J0I8_9GAMM/1704-1811 .......GETIKLTIHTK.GQDGR.DIGGVPVTINL.KAENRKQ-----.............--VPEIVTVK...LEKETGALESNgs.....gdVYTGHTDEKGDLIIEVTD.PDGIGTRTELVVTV.NDDGNKLneQKQDVIFTVI.....
Q8ZN55_SALTY/1025-1138 .......GETMQLKVTVK.DVSGN.PIPEAPFVLTR.GDGYDRRGEKYTaq........dgdDLQGIVTPVV...IDGESLAWTTT.........KMGSQTGTDGTRIISVTR.PDTHGTRTAINATL.YENAAVS..ASIDTIFTVV.....
A0A3D9U9H4_9GAMM/760-855 .......GETVILNIKAF.-NHGQ.PVKNVPIEMKA.TRALNRQE----.............--VPQTVTAL...INSESG-----.........HYQGITGDQGSLSLPIID.PNGLGVKTTLQIKA.YGVSNP-..KTEDVIFTVV.....
A0A2X4UST9_9GAMM/221-323 ......g-GKITLTVTTK.DCQGN.LAGNIPFVIKR.GDAKNRQG----.............-AVNNAAPVA...LGSTELTTTAT.........EYRGTTDANGVATVEVTQ.PNGLGVKTPLFAGL.PGISQT-..SETAVIFTVL.....
B7MHZ1_ECO45/740-852 .......GDTITMTVRTFnALNNA.PVPYTAFTITK.DMGKNRQGQTTG.............FDDPTRGAIE...MNGTLYGTSQPs.......lVYAGTTDAQGFATVEIKQ.SQGVGLSTPLNIVP.VNSYIPN.tVNYNVIFTT-l....
B7MHZ1_ECO45/1875-1987 ......g-TAIRMTVIVR.DSGGN.LLPGANFNLIR.GTALDRAKNRLD.............-STYDDLTIV...PVTPAGVNMSLyn....ngaQALLTTGSDGKATFDVTQ.NETYGLATPLTATL.MRDTTKS..ATMDVIFTVI.....
A0A0H2VBV9_ECOL6/2437-2551 .......GEAMSVTVTVK.DSAGN.TVPNVEFTLKR.GEASPRNAGATLy..........gnVVAMDDLVVQ...--PLSGSAVTLse....sgnTISGMTGADGTASFSLRQ.DNTPGYKTPLTVTL.ANYASAT..DTLDAIFTV-p....
Q8ZN55_SALTY/748-857 .......GEQVKMNIHSRnALNGM.AIGNTDFTITM.ANGRRRDGLTTG.............FTDTSNGEMQ...FDDVGYVAGQ-.........VYHGITDANGDATIILTQ.KKGVGLLTPLNIAP.VDSLIST.pVSRSVKFTVA.....
A0A4Z0MG49_SALET/39-158 .......GSAMPLTVTVK.DSSGN.PVANVGFTLSR.GDSKNRAGTVVTdgd.......vaaDAGADDLMLK...ALAPASASQSMtt....tgiVFTGTTGSDGTATFTLNQ.DKSLGLKTPLTVKL.TDNTTLH..ASLDVIFMVL.....
B7UGU8_ECO27/210-313 .......GETITLTLTVK.DCDGN.LKAGTPFTVRR.GVPTNRQNVA--.............--NDTGAPVS...LGGTVMTDTTT.........EYKGVTGEGGIATIAVTQ.NEGIGVKTPLYITA.TGMSTP-..LTQDVTFTVI.....
A0A4Z0KGP0_SALET/1-82 lpvpanv-----------.-ACGN.PVPDAPFVLSR.GDGYTRQGEKHIa...........gSGDGIVSAVV...IDGESLNDTAT.........KIGEVTGEDGSKIINVTR.PDTHGTK-------.-------..----------.....
W1IZ47_9GAMM/380-485 ......s-DTAQLTVSTL.NKNKT.PAPWVHVEITL.SGEDRKSK----.............TVPDADVKTR...LAPSKGNYATT.........KYEGYTDGTGQLVMTVSD.PDGKGIQTYLRARA.-DTLMGAvsDTHSIIFTVI.....
A0A0H2Z1J0_ECOK1/1875-1987 ......g-TAIRMTVIVR.DSGGN.LLPGANFNLIR.GTALDRAKNRLD.............-STYDDLTIV...PVTPAGVNMSLyn....ngaQALLTTGSDGKATFDVTQ.NETYGLATPLTATL.MRDTTKS..ATMDVIFTVI.....
A0A0H3EM56_ECO8N/740-852 .......GDTITMTVRTFnALNNA.PVPYTAFTITK.DMGKNRQGQTTG.............FDDPTRGAIE...MNGTLYGTSQPs.......lVYAGTTDAQGFATVEIKQ.SQGVGLSTPLNIVP.VNSYIPN.tVNYNVIFTT-l....
A0A2X4UST9_9GAMM/1029-1145 .......GETLRVKVTVK.DAQGN.PMPDMPFTLNR.GDGYTHYPVERYiag.......aggT---LVSSVV...VDGGQPD---Emtls.dktaTYTAMTDSSGSKMLNITR.PDTRGTKTALTVAL.YSDPTKK..ASMDTIFTV-p....
A0A0H3EM56_ECO8N/214-316 .......GGSITLTVTTK.DCVGN.VVGNIPFVIKR.KDAENRQG----.............-VVNNTAPVK...LGTTELTTTAT.........EYRGTTDANGVATVTVTQ.ANGPGVKTPLVASL.AGIAQA-..SETAVIFTVL.....
A0A2X4UST9_9GAMM/1318-1432 ......k-DSIVVKVTTR.DAQGQ.PLGNVPFTLNH.GTTVARNTNT-I.............AIDTMSKQVS...VQDSYSHSSEYfy....dtsRYYSRTGPDGTVEFTLHQtNKGMGTRIPLTAQTdDGSGLSS..NTLSAIFTVV.....
A0A0H3EM56_ECO8N/474-584 ...geea--SLRLTITDS.KNNDQ.PLAYYYFSLHL.DDGINRKNQTDA.............AWETHPVQID...GGSNVRKVDAH.........TYEGITDANGEATLTLTQ.PGGVGVKTHITARM.RSDFTAS..DEKDVIFTVI.....
Q8ZN55_SALTY/224-327 .......GESITLTISTK.ACDGT.PEGNAPFVIRR.KDAENRQG----.............-VVNNANPVR...VGDTELTTTQT.........EYRGVTDANGNATVVVTQ.KEGPGVKTPLVVSS.VNFPALT..AETAVIFTTI.....
A0A0H2VBV9_ECOL6/2160-2273 .......GEMLPIVVTIK.DANGN.PVGGEGVTLKR.VQAKSRSGISVS.............SNTVDDLILD...EVTPTSARISFnq....ntsAWSGFTGSDGTITFNVTQ.NNTVGLVTPFTASL.ARNPQVT..ANQDLIFTVV.....
A0A0H3EM56_ECO8N/2160-2273 .......GEMLPIVVTIK.DANGN.PVGGEGVTLKR.VQAKSRSGISVS.............SNTVDDLILD...EVTPTSARISFnq....ntsAWSGFTGSDGTITFNVTQ.NNTVGLVTPFTASL.ARNPQVT..ANQDLIFTVV.....
A0A4Z0L7R2_SALET/163-270 .......GETIPVTITTL.DAQGK.PVADTPVIFTR.GDSIGRANQEVN.............--GSQAAAIQ...INHSAARNSGV.........EYYPATGADGTLTLDISQ.DGGAGFKTPLMASI.EHSNATT.tAPLPVIFTVV.....
A0A0H2Z1J0_ECOK1/1019-1134 .......GETLQVKVTVK.DAQGN.PLGDIPFTLKR.GDGYTRSEEKHVa...........gSSDALVAPVV...VNGGLADETSLnn....taaAYSAMTGSDGTKILTITR.PDTHGTKTSLTARL.YSDTTKK..ATLDTIFTVV.....
Q8ZN56_SALTY/1312-1418 .......GETIPVIITTR.DAQGN.PAADTPVIFTR.GDSVGRANQEVN.............--SSAAADIQ...INHSDGRSSGA.........NYYTATGADGTLTLNISQ.DSGAGFKTPLTAAI.EHNGVTS..APLPVIFTVV.....
A0A0H2VBV9_ECOL6/1594-1702 .......GEDAVIRVVTK.NAQGN.SVPNVPFILRR.EGSKNRQNAEMI.............--NKSITVIN...AAGASARMNSSs.......sLLYGVTGADGTTSFTVKQ.DDSMGLVTNMYAQL.YQLTIES..NKLPVMFTVI.....
A0A2D0KTV7_9GAMM/776-871 .......GETITLSVQTF.-NHGH.PVRNVPVEVKT.TEALNRQN----.............--IHQAVTLQ...VNGNAG-----.........HYQGVTGDNGTLSLPLTD.PHGLGVKTTLQVAG.YGVSAP-..QTENVIFTVA.....
B7MHZ1_ECO45/214-316 .......GGSITLTVTTK.DCVGN.VVGNIPFVIKR.KDAENRQG----.............-VVNNTAPVK...LGTTELTTTAT.........EYRGTTDANGVATVTVTQ.ANGPGVKTPLVASL.AGIAQA-..SETAVIFTVL.....
Q8ZN56_SALTY/2177-2296 .......GSAMPLTVTVK.DSSGN.PVANVGFTLSR.GDSKNRAGMVITdgd.......vaaDAGADDLMLK...ELTPASASQSMtt....tgiVFTGTTGSDGTATFTLNQ.DKSLGLKTPLTVKV.TDNTTLH..ASLDVIFMVL.....
A0A0H2VBV9_ECOL6/740-852 .......GDTITMTVRTFnALNNA.PVPYTAFTITK.DMGKNRQGQTTG.............FDDPTRGAIE...MNGTLYGTSQPs.......lVYAGTTDAQGFATVEIKQ.SQGVGLSTPLNIVP.VNSYIPN.tVNYNVIFTT-l....
B7MHZ1_ECO45/1019-1134 .......GETLQVKVTVK.DAQGN.PLGDIPFTLKR.GDGYTRSEEKHVa...........gSSDALVAPVV...VNGGLADETSLnn....taaAYSAMTGSDGTKILTITR.PDTHGTKTSLTARL.YSDTTKK..ATLDTIFTVV.....
A0A0H2Z1J0_ECOK1/2160-2273 .......GEMLPIVVTIK.DANGN.PVGGEGVTLKR.VQAKSRSGISVS.............SNTVDDLILD...EVTPTSARISFnq....ntsAWSGFTGSDGTITFNVTQ.NNTVGLVTPFTASL.ARNPQVT..ANQDLIFTVV.....
A0A4Z0PRR7_SALET/1-57 .vrcgde-----------.-----.-----------.------------.............----------...---------TG.........YWYGTTDESGRVQFELTQ.DNTPGLKTRLEAML.PDDPPTV..SDMDAIFTVI.....
A0A1I0AU25_9GAMM/452-549 .....ng--SIDMTIVVR.DKFRQ.SMPYMPVSINT.IKSVNRQN----.............-VESFVKYLR...FNGRPGSSAA-.........--HFTTDENGVLKITITE.AYTLGRESTFQVSS.HNAL---..KTDSVKFTVL.....
Q8ZN56_SALTY/1034-1144 .......GDTLQLKVTVK.DASGN.PLPQAPFVLSR.GDGYTRQGEKHIa...........gSGDGIVSAVV...IDGDSLNDTAT.........KIGGMTGENGSKIINVTR.PDTHGTKVAITAAL.YDNASAT..ASIDTIFTVV.....
A0A0H2VBV9_ECOL6/1307-1418 .......GEEAVLRVTTK.DAQGK.PVGNTAFTLKR.NTSVNRANVSTT.............TSIASLAVTDawgNTQNDFLSTTL.........VIYGVTGADGTTTFTLKQ.DQTTGLKTELTAAL.DSSSSTK..STLPVVFTVL.....
B7MHZ1_ECO45/1594-1702 .......GEDAVIRVVTK.NAQGN.SVPNVPFILRR.EGSKNRQNAEMI.............--NKSITVIN...AAGASARMNSSs.......sLLYGVTGADGTTSFTVKQ.DDSMGLVTNMYAQL.YQLTIES..NKLPVMFTVI.....
A0A0H2Z1J0_ECOK1/2437-2551 .......GEAMSVTVTVK.DSAGN.TVPNVEFTLKR.GEASPRNAGATLy..........gnVVAMDDLVVQ...--PLSGSAVTLse....sgnTISGMTGADGTASFTLRQ.DNTPGYKMPLTVTL.ANYASAT..DTLDAIFTV-p....
B7MHZ1_ECO45/2160-2273 .......GEMLPIVVTIK.DANGN.PVGGEGVTLKR.VQAKSRSGISVS.............SNTVDDLILD...EVTPTSARISFnq....ntsAWSGFTGSDGTITFNVTQ.NNTVGLVTPFTASL.ARNPQVT..ANQDLIFTVV.....
A0A0H2Z1J0_ECOK1/214-316 .......GGSITLTVTTK.DCVGN.VVGNIPFVIKR.KDAENRQG----.............-VVNNTAPVK...LGTTELTTTAT.........EYRGTTDANGVATVTVTQ.ANGPGVKTPLVASL.AGIAQA-..SETAVIFTVL.....
Q8ZN56_SALTY/1605-1720 .......GEQMAATIDVK.DAAGQ.PMKNVMVKISR.GSSYNRANSATS............sSSITDDITLR...NVMPSGLATYLldt...sakYLYAQTDAQGQVTFTLAQ.DSTAGLKTTISAAT.MDGSNLT..DSKDAIFTVV.....
A0A077P4B5_XENBV/1304-1408 .....dk--TITFTVKTE.-DGGQ.AIGGVPVTIKM.-TAINRQK----.............--KSDTVTVN...LDAKKGVLAGKe.......dTYRGHTDENGHLVINVTD.PNGIGTRTTLSVEV.NDGANKTltKTWDVIFTVL.....
Q8ZN56_SALTY/1892-2008 .......GESLPLTVTVR.DGSGT.PQPNTAIRLGR.TLSIDRAGVVDG.............-SSGGGMVLT...SVAPSTGSMTFnctvssctsYWYGITDEDGKAQLEVTQ.DDSRGLRTPLQAML.VDDPLTV..SDMDVIFTVI.....
Q8ZN56_SALTY/220-323 .......GESIMLTVTTK.DCGGE.PEGNVDFVITR.GDAQNRQG----.............-VVNNAAPVR...VGNTELTTTAT.........EYHGTTNAEGVATVVVTQ.ANGPGVKTPLIAHP.SSAPALK..ASVDVIFTT-l....
A0A4Z0KBT4_SALET/14-117 .......GESITLTVNTK.GCNGE.PAGNIAFVITR.GDALNRQG----.............-VVNNTAPVR...VGNTELTTTAT.........EYHGTTKAEGVATVTVAQ.ANGPGVKTPLVAHP.SGAPALK..ADVDVIFTT-l....
A0A2X4UST9_9GAMM/481-591 ...gdtt--TMRLSITDR.LNGNQ.PLAYYYFSLSL.DGGTNRKGQTDA.............SWETHPVLIT...GGTRLHRVDAH.........TYEGITDVNGEATLALSQ.PEGAGVKTHITARM.RSNFSTT..DAKDVIFTVI.....
A0A0H2Z1J0_ECOK1/1307-1418 .......GEEAVLRVTTK.DAQGK.PVGNTAFTLKR.NTSVNRANVSTT.............TSIASLAVTDawgNTQNDFLSTTL.........VIYGVTGADGTTTFTLKQ.DQTTGLKTELTAAL.DSSSSTK..STLPVVFTVL.....
Q8ZN56_SALTY/754-866 .......GEQITMNVHSVnALNGL.SVPNASFTVTM.SHGKNRDNATTG.............FTDPSDGTLV...MGGTPFGSSQAs.......mTYQGMTDAEGNATLVIEQ.PQGVGLLTPLSVLP.VNSLITT.pVNRSVKFTVA.....
W1IWM1_9GAMM/760-855 .......DEPITLKIETF.-NHGQ.SVRNVSVNVKA.VQAMNRQK----.............--HDEKITIL...LNGNLG-----.........ETQAYTDDQGVLSLPVAD.PFGLGVKTTLSVTA.DGTAPS-..ETRDVTFTVA.....
A0A2X4UST9_9GAMM/1603-1717 .......GDTMPITVTVK.DSMGN.PVPNVAFTLTR.GAASPRNSGATL............yDNVDAMDDLK...VQPSSGSAVTMte....sgnSLQGMTGADGSATFTVRQ.DDTLGYKTPLTVTL.DQYANVT..STLETIFTV-n....
A0A0H3EM56_ECO8N/1019-1134 .......GETLQVKVTVK.DAQGN.PLGDIPFTLKR.GDGYTRSEEKHVa...........gSSDALVAPVV...VNGGLADETSLnn....taaAYSAMTGSDGTKILTITR.PDTHGTKTSLTARL.YSDTTKK..ATLDTIFTVV.....
A0A0H3EM56_ECO8N/2437-2551 .......GEAMSVTVTVK.DSAGN.TVPNVEFTLKR.GEASPRNAGATLy..........gnVVAMDDLVVQ...--PLSGSAVTLse....sgnTISGMTGADGTASFSLRQ.DNTPGYKTPLTVTL.ANYASAT..DTLDAIFTV-p....
A0A0H2VBV9_ECOL6/1019-1134 .......GETLQVKVTVK.DAQGN.PLGDIPFTLKR.GDGYTRSEEKHVa...........gSSDALVAPVV...VNGGLADETSLnn....taaAYSAMTGSDGTKILTITR.PDTHGTKTSLTARL.YSDTTKK..ATLDTIFTVV.....
Q8ZN55_SALTY/484-594 .......GESIDLTMTVV.DRDTQkPLPYRYMELFI.DPAKNRKGEHQD.............AWDNLRVTVD...SEGMSASSPE-.........HYTGVTDVNGQAHLTLKH.NSGLGVETPIRIVM.PDDEGGNveLSFSVIFTVV.....
A0A0H3EM56_ECO8N/1594-1702 .......GEDAVIRVVTK.NAQGN.SVPNVPFILRR.EGSKNRQNAEMI.............--NKSITVIN...AAGASARMNSSs.......sLLYGVTGADGTTSFTVKQ.DDSMGLVTNMYAQL.YQLTIES..NKLPVMFTVI.....
B7MHZ1_ECO45/2437-2551 .......GEAMSVTVTVK.DSAGN.TVPNVEFTLKR.GEASPRNAGATLy..........gnVVAMDDLVVQ...--PLSGSAVTLse....sgnTISGMTGADGTASFTLRQ.DNTPGYKMPLTVTL.ANYASAT..DTLDAIFTV-p....
A0A0H2Z1J0_ECOK1/1594-1702 .......GEDAVIRVVTK.NAQGN.SVPNVPFILRR.EGSKNRQNAEMI.............--NKSITVIN...AAGASARMNSSs.......sLLYGVTGADGTTSFTVKQ.DDSMGLVTNMYAQL.YQLTIES..NKLPVMFTVI.....
B7MHZ1_ECO45/474-584 ...geea--SLRLTITDS.KNNDQ.PLAYYYFSLHL.DDGINRKNQTDA.............AWETHPVQID...GGSNVRKVDAH.........TYEGITDANGEATLTLTQ.PGGVGVKTHITARM.RSDFTAS..DEKDVIFTVI.....
A0A845SI55_9GAMM/789-884 .......GEVVQMTIEAQ.YASGA.PVRDFNVDIRP.TTAIGRTR----.............-PRREPITAS...INGASM-----.........-YSGKTDNSGKITLAISD.DDTIGLKTTYTVTP.EAG--AA..VTREVIFSV-t....
B7MHZ1_ECO45/1307-1418 .......GEEAVLRVTTK.DAQGK.PVGNTAFTLKR.NTSVNRANVSTT.............TSIASLAVTDawgNTQNDFLSTTL.........VIYGVTGADGTTTFTLKQ.DQTTGLKTELTAAL.DSSSSTK..STLPVVFTVL.....
W1J0T3_9GAMM/1688-1793 ......p-DPIKLAINTT.-NADN.PIGGVPVTIK-.LTAMNRQKAP--.............-VDADKVTVK...LQAEEGVLEGSg.......vTYTGHTDDKGNLIINVTD.PDGIGTRTTLSITV.NESTPQT..KTLDVIFTVI.....
A0A6H2FA16_9ENTR/670-781 ......y-DHIILKINLL.NLNHQ.PVNKAYNIIVRiLSINDRQGKKRTds.........gkLQILNNNKVN...NNKVNI-SNNT.........KYQFTTNNDGTLQLDISD.PDGIGVKTKISISI.PQTNIT-..SNISLIYAV-p....
A0A2I0FS34_9GAMM/1692-1790 .......GDTIQLTVTAVrKGTTT.LAPYVKISLKE.TQVLNRQNNA--.............---ATSGGVN...ANSASL----A.........SYQGITDANGQVTISLTD.PAGTGVKTTLEAKS.-DNGDT-..NTQDVTFNV-k....
Q8ZN55_SALTY/1315-1428 .......SESIPLLITTT.DAMGN.PVPYATFSLKR.DAGKARNPDYNK.............FVATNGTNMT...VTPLTGAQQQFyy....atsVLTGATGADGTLALTLAE.PGGIGLKNQLTANL.NDTPTAT..SSLPVVFTVL.....
A0A4Z0PGN6_SALET/33-121 .......GDDINMKISVT.DSATNkPLPYRYFNVYL.GDEQTRQTPKNPdi.........daAHQWSDAPVV...ISNLAGSAG--.........LYPGVTAATGACSLALRH.ERG-----------.-------..----------gagvp
A0A0H2VBV9_ECOL6/1875-1987 ......g-TAIRMTVIVR.DSGGN.LLPGANFNLIR.GTALDRAKNRLD.............-STYDDLTIV...PVTPAGVNMSLyn....ngaQALLTTGSDGKATFDVTQ.NETYGLATPLTATL.MRDTTKS..ATMDVIFTVI.....
A0A0H3EM56_ECO8N/1307-1418 .......GEEAVLRVTTK.DAQGK.PVGNTAFTLKR.NTSVNRANVSTT.............TSIASLAVTDawgNTQNDFLSTTL.........VIYGVTGADGITTFTLKQ.DQTTGLKTELTAAL.DSSSSTK..STLPVVFTVL.....
#=GC seq_cons .......G-slslsVss+.cssGs.PlssssFslpR.ssuhsRps.t................ssssssslp...hsssstssssh.........tapGhTsusGssolsloQ.ssuhGlKTsLsssl.hssssss..sshsVIFTVl.....
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