#=GF ID BRD4_CDT
#=GF AC PF17105.11
#=GF DE C-terminal domain of bromodomain protein 4
#=GF AU Coggill P;0000-0001-5731-1588
#=GF SE Pfam-B_361 (release 27)
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.10;
#=GF NC 26.90 26.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 90746521 --cpu 8 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 16109376
#=GF RT The bromodomain protein Brd4 is a positive regulatory component
#=GF RT of P-TEFb and stimulates RNA polymerase II-dependent
#=GF RT transcription.
#=GF RA Jang MK, Mochizuki K, Zhou M, Jeong HS, Brady JN, Ozato K;
#=GF RL Mol Cell. 2005;19:523-534.
#=GF RN [2]
#=GF RM 21555454
#=GF RT The Brd4 extraterminal domain confers transcription activation
#=GF RT independent of pTEFb by recruiting multiple proteins, including
#=GF RT NSD3.
#=GF RA Rahman S, Sowa ME, Ottinger M, Smith JA, Shi Y, Harper JW,
#=GF RA Howley PM;
#=GF RL Mol Cell Biol. 2011;31:2641-2652.
#=GF DR INTERPRO; IPR031354;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC BRD4_CDT is the short highly conserved C-terminal domain of
#=GF CC certain bromodomain proteins, notably Brd4. The Brd4 CTD
#=GF CC interacts with the cyclin T1 and Cdk9 subunits of positive
#=GF CC transcription elongation factor b (pTEFb) complex. Brd4
#=GF CC displaces negative regulators, the HEXIM1 and 7SKsnRNA complex,
#=GF CC from pTEFb, thereby transforming it into an active form that can
#=GF CC phosphorylate RNA pol II [1,2].
#=GF SQ 1720
#=GS A0A7J8F7H9_MOLMO/691-734 AC A0A7J8F7H9.1
#=GS A0A7M7PP55_STRPU/1286-1328 AC A0A7M7PP55.1
#=GS A0A4Z2AYW4_9TELE/1304-1346 AC A0A4Z2AYW4.1
#=GS A0A091LLG0_CATAU/931-974 AC A0A091LLG0.1
#=GS A0A8T0AHQ8_SILME/1501-1544 AC A0A8T0AHQ8.1
#=GS A0A7L1P0J4_ORIOR/914-957 AC A0A7L1P0J4.1
#=GS A0A7L0HT98_AREIN/914-954 AC A0A7L0HT98.1
#=GS A0A7L4F136_HIRRU/902-945 AC A0A7L4F136.1
#=GS A0A6P7XBU1_9AMPH/1355-1398 AC A0A6P7XBU1.1
#=GS A0A6P6K8Y3_CARAU/1478-1521 AC A0A6P6K8Y3.1
#=GS A0A8B6DL08_MYTGA/1158-1210 AC A0A8B6DL08.1
#=GS A0A8J6FL40_ELECQ/1307-1350 AC A0A8J6FL40.1
#=GS A0A8M1FSL1_URSMA/1249-1292 AC A0A8M1FSL1.1
#=GS A0A3Q0D2Z6_MESAU/887-930 AC A0A3Q0D2Z6.1
#=GS A0A4S2JRA4_9HYME/1497-1539 AC A0A4S2JRA4.1
#=GS A0A8B8FM33_9HEMI/1229-1272 AC A0A8B8FM33.1
#=GS A0A3P7WB57_9BILA/196-230 AC A0A3P7WB57.1
#=GS A0A2K5VQT1_MACFA/858-901 AC A0A2K5VQT1.1
#=GS A0A7L1G8U3_9PICI/2-45 AC A0A7L1G8U3.1
#=GS A0A8I5YN93_PONAB/887-930 AC A0A8I5YN93.1
#=GS A0A9D3NQI8_9TELE/1037-1080 AC A0A9D3NQI8.1
#=GS A0AAD7RBC2_9TELE/900-943 AC A0AAD7RBC2.1
#=GS A0A151M523_ALLMI/851-894 AC A0A151M523.1
#=GS A0A3Q4B9A2_MOLML/151-194 AC A0A3Q4B9A2.1
#=GS A0AAJ7NBF2_9HYME/1464-1506 AC A0AAJ7NBF2.1
#=GS A0AA88T8I9_TACVA/1058-1101 AC A0AA88T8I9.1
#=GS A0A1S3PAC6_SALSA/1109-1152 AC A0A1S3PAC6.1
#=GS A0A3Q2C698_CYPVA/1465-1508 AC A0A3Q2C698.1
#=GS A0A7K5TXA5_CEPOR/903-946 AC A0A7K5TXA5.1
#=GS A0A7K9S9Z5_9PASS/914-957 AC A0A7K9S9Z5.1
#=GS A0A9N9MXM1_9CUCU/1282-1325 AC A0A9N9MXM1.1
#=GS M4AG86_XIPMA/1369-1412 AC M4AG86.2
#=GS A0A2U9C797_SCOMX/883-924 AC A0A2U9C797.1
#=GS A0AAD9DVT4_9TELE/1153-1196 AC A0AAD9DVT4.1
#=GS A0A834C7Q5_ORYME/821-863 AC A0A834C7Q5.1
#=GS A0A914GUC5_GLORO/1082-1124 AC A0A914GUC5.1
#=GS A0AA39GQZ5_9BILA/1073-1115 AC A0AA39GQZ5.1
#=GS A0A6P3IWR5_BISBB/887-930 AC A0A6P3IWR5.1
#=GS A0A8J9VIW9_9NEOP/1276-1318 AC A0A8J9VIW9.1
#=GS A0A0V1M640_9BILA/1088-1130 AC A0A0V1M640.1
#=GS A0A5E4C1I6_MARMO/40-83 AC A0A5E4C1I6.1
#=GS A0A812E427_ACAPH/1092-1134 AC A0A812E427.1
#=GS A0A3Q0HMZ4_ALLSI/1377-1420 AC A0A3Q0HMZ4.1
#=GS A0A093PR46_9PASS/892-935 AC A0A093PR46.1
#=GS A0A671XAT8_SPAAU/1465-1508 AC A0A671XAT8.1
#=GS A0A8N4QL00_BACDO/1849-1892 AC A0A8N4QL00.1
#=GS A0A8U0TKK8_SALNM/1351-1394 AC A0A8U0TKK8.1
#=GS A0A1I8M9M6_MUSDO/1699-1741 AC A0A1I8M9M6.1
#=GS A0A1D2MZJ8_ORCCI/1118-1161 AC A0A1D2MZJ8.1
#=GS A0AA36HFX3_CYLNA/1244-1284 AC A0AA36HFX3.1
#=GS A0A9W2XWN0_BETSP/1321-1363 AC A0A9W2XWN0.1
#=GS A0A915AKI7_PARUN/1110-1153 AC A0A915AKI7.1
#=GS A0A8C9JMW3_PANTA/146-168 AC A0A8C9JMW3.1
#=GS A0AA40L578_PYGPA/922-965 AC A0AA40L578.1
#=GS A0A452SSS5_URSAM/1266-1288 AC A0A452SSS5.1
#=GS A0A0D9R1C4_CHLSB/1322-1365 AC A0A0D9R1C4.1
#=GS A0A673FYJ7_9TELE/1400-1443 AC A0A673FYJ7.1
#=GS A0A6J2PFJ3_COTGO/1313-1356 AC A0A6J2PFJ3.1
#=GS A0A016TAB0_9BILA/158-198 AC A0A016TAB0.1
#=GS A0A3Q0HJ26_ALLSI/1312-1355 AC A0A3Q0HJ26.1
#=GS A0A7K5MDN6_CARCD/887-930 AC A0A7K5MDN6.1
#=GS A0A6J2YKT1_SITOR/1336-1378 AC A0A6J2YKT1.1
#=GS A0A5S6PML5_BRUMA/998-1040 AC A0A5S6PML5.1
#=GS A0AA88Q944_9TELE/1422-1465 AC A0AA88Q944.1
#=GS A0A9P0JCL9_APHGO/1221-1264 AC A0A9P0JCL9.1
#=GS A0A6G0HWD0_LARCR/1558-1601 AC A0A6G0HWD0.1
#=GS A0A851FPN3_PITSO/891-933 AC A0A851FPN3.1
#=GS A0A8C9KEY3_PANTA/855-897 AC A0A8C9KEY3.1
#=GS A0A8C0AHS2_BOSMU/162-205 AC A0A8C0AHS2.1
#=GS A0AA35NW04_9SAUR/1318-1361 AC A0AA35NW04.1
#=GS A0A7K9C9E3_9PICI/929-971 AC A0A7K9C9E3.1
#=GS A0A671V3M5_SPAAU/892-934 AC A0A671V3M5.1
#=GS A0A1U8CSQ0_MESAU/1212-1255 AC A0A1U8CSQ0.1
#=GS A0A6P7GRV9_DIAVI/1142-1184 AC A0A6P7GRV9.1
#=GS A0A852P3W6_9PASS/896-939 AC A0A852P3W6.1
#=GS A0A5F7ZHC5_MACMU/170-213 AC A0A5F7ZHC5.1
#=GS A0A6J8CUG6_MYTCO/752-795 AC A0A6J8CUG6.1
#=GS G5ASI3_HETGA/789-832 AC G5ASI3.1
#=GS A0A8B7NCY4_HYAAZ/1817-1858 AC A0A8B7NCY4.2
#=GS F7FHI3_MACMU/1291-1334 AC F7FHI3.3
#=GS A0A8J2S8D6_9CRUS/1442-1484 AC A0A8J2S8D6.1
#=GS A0A3Q3AQN4_KRYMA/1400-1443 AC A0A3Q3AQN4.1
#=GS A0A218VEM9_9PASE/841-884 AC A0A218VEM9.1
#=GS A0A1S3AMK0_ERIEU/1183-1226 AC A0A1S3AMK0.1
#=GS A0A6P7UAR8_OCTVU/1180-1222 AC A0A6P7UAR8.1
#=GS A0AA39GP10_9BILA/1057-1099 AC A0AA39GP10.1
#=GS A0A851AUN0_PICGY/2-45 AC A0A851AUN0.1
#=GS A0A7L1ZRC1_LEILU/892-935 AC A0A7L1ZRC1.1
#=GS A0A8K0AAN2_BRALA/1268-1310 AC A0A8K0AAN2.1
#=GS A0A672GBS9_SALFA/1337-1380 AC A0A672GBS9.1
#=GS A0A6P8YI32_THRPL/1606-1648 AC A0A6P8YI32.1
#=GS A0A7K5H360_9AVES/2-45 AC A0A7K5H360.1
#=GS A0A4X1U655_PIG/843-885 AC A0A4X1U655.1
#=GS A0A5E4C5B2_MARMO/858-901 AC A0A5E4C5B2.1
#=GS A0A8P4G162_DICLA/917-959 AC A0A8P4G162.1
#=GS A0A087VCM3_BALRE/932-975 AC A0A087VCM3.1
#=GS A0A0R4IJ54_DANRE/936-979 AC A0A0R4IJ54.1
#=GS A0A5J5N276_MUNRE/1304-1347 AC A0A5J5N276.1
#=GS A0A4Z2BAR7_9TELE/203-245 AC A0A4Z2BAR7.1
#=GS A0A6P7M7W5_BETSP/892-934 AC A0A6P7M7W5.1
#=GS A0A821N723_9NEOP/1231-1273 AC A0A821N723.1
#=GS A0A8C7YFX7_9TELE/1462-1505 AC A0A8C7YFX7.1
#=GS A0A6P3XVP5_DINQU/1460-1502 AC A0A6P3XVP5.1
#=GS A0A6F9B8A0_9TELE/1070-1113 AC A0A6F9B8A0.1
#=GS BRDT_HUMAN/904-947 AC Q58F21.4
#=GS A0A3S2MLR0_ORYJA/1450-1493 AC A0A3S2MLR0.1
#=GS A0A6I9WSE4_9HYME/1461-1503 AC A0A6I9WSE4.1
#=GS A0A6P8Q1S2_GEOSA/1324-1367 AC A0A6P8Q1S2.1
#=GS A0A3B5QCL5_XIPMA/1489-1532 AC A0A3B5QCL5.1
#=GS A0A8C1JV30_CYPCA/1405-1448 AC A0A8C1JV30.1
#=GS A0A6P8G6J7_CLUHA/947-990 AC A0A6P8G6J7.1
#=GS A0A8C4GXE9_DICLA/1381-1424 AC A0A8C4GXE9.2
#=GS A0A3Q2UVR0_HAPBU/1412-1455 AC A0A3Q2UVR0.1
#=GS A0A8U0R5S0_SALNM/1113-1156 AC A0A8U0R5S0.1
#=GS A0A673Y9Q1_SALTR/1447-1490 AC A0A673Y9Q1.1
#=GS A0A182E052_ONCOC/958-1000 AC A0A182E052.1
#=GS A0A9P0TD10_PIEBR/1220-1262 AC A0A9P0TD10.1
#=GS A0A093QU12_PYGAD/924-967 AC A0A093QU12.1
#=GS H2PZD9_PANTR/858-901 AC H2PZD9.2
#=GS A0A8W8LDR7_MAGGI/1193-1235 AC A0A8W8LDR7.1
#=GS A0A913Z1H7_PATMI/1421-1463 AC A0A913Z1H7.1
#=GS A0A2Y9LYI1_DELLE/1354-1397 AC A0A2Y9LYI1.1
#=GS A0A3N0YZ57_ANAGA/1465-1508 AC A0A3N0YZ57.1
#=GS E9HM71_DAPPU/247-290 AC E9HM71.1
#=GS A0A6P8PI04_GEOSA/1325-1368 AC A0A6P8PI04.1
#=GS A0A8B8FKW6_9HEMI/1177-1220 AC A0A8B8FKW6.1
#=GS A0A7L0PWU1_9AVES/908-951 AC A0A7L0PWU1.1
#=GS F6THA1_HORSE/885-910 AC F6THA1.3
#=GS A0A7K5WC42_9SYLV/895-938 AC A0A7K5WC42.1
#=GS A0A8D0CNR7_SANLU/1269-1312 AC A0A8D0CNR7.1
#=GS A0A3P9C9U3_9CICH/163-206 AC A0A3P9C9U3.1
#=GS A0A8C3R8B4_9PASS/965-1008 AC A0A8C3R8B4.1
#=GS G3UG48_LOXAF/1300-1343 AC G3UG48.1
#=GS A0A6J3FE77_SAPAP/907-950 AC A0A6J3FE77.1
#=GS A0A8C5W7L5_MICMU/825-867 AC A0A8C5W7L5.1
#=GS A0A1S3S649_SALSA/1491-1534 AC A0A1S3S649.1
#=GS A0A6P8N9C5_GEOSA/1001-1044 AC A0A6P8N9C5.1
#=GS A0A1D5Q1K8_MACMU/904-947 AC A0A1D5Q1K8.2
#=GS A0AA39FMH2_9HYME/1476-1518 AC A0AA39FMH2.1
#=GS A0A7K9E548_BARMA/2-45 AC A0A7K9E548.1
#=GS A0A7R9PZF5_9ACAR/637-677 AC A0A7R9PZF5.1
#=GS A0A7K8KUM1_9AVES/902-945 AC A0A7K8KUM1.1
#=GS A0A7L1VP54_SITEU/904-947 AC A0A7L1VP54.1
#=GS A0A6J2YIN3_SITOR/1188-1230 AC A0A6J2YIN3.1
#=GS A0AAD3N0S4_LATJO/941-983 AC A0AAD3N0S4.1
#=GS A0AAE0SXX1_9BIVA/1234-1276 AC A0AAE0SXX1.1
#=GS A0A8C4DF38_DICLA/963-1005 AC A0A8C4DF38.2
#=GS A0A8D2GQ77_UROPR/1328-1371 AC A0A8D2GQ77.1
#=GS A0A9J7MWN4_BRAFL/1354-1396 AC A0A9J7MWN4.1
#=GS H2QFM0_PANTR/1290-1333 AC H2QFM0.2
#=GS A0A834C4A0_ORYME/1365-1408 AC A0A834C4A0.1
#=GS A0A7E6EBA9_9CHIR/1205-1248 AC A0A7E6EBA9.1
#=GS A0A7L4AWT9_9CHAR/907-950 AC A0A7L4AWT9.1
#=GS A0A7F5R1N9_AGRPL/1250-1292 AC A0A7F5R1N9.1
#=GS A0A0C2DKX7_9BILA/133-174 AC A0A0C2DKX7.1
#=GS G1T4I8_RABIT/1264-1307 AC G1T4I8.2
#=GS A0A673MX05_9TELE/1397-1422 AC A0A673MX05.1
#=GS W5MIW9_LEPOC/1504-1547 AC W5MIW9.1
#=GS A0A3Q0D1G4_MESAU/882-925 AC A0A3Q0D1G4.1
#=GS A0A674A188_SALTR/1584-1627 AC A0A674A188.1
#=GS A0A8C0YCL0_CYPCA/1473-1516 AC A0A8C0YCL0.2
#=GS A0AA36DC28_9BILA/905-947 AC A0AA36DC28.1
#=GS A0A8B8DJ27_CRAVI/1196-1238 AC A0A8B8DJ27.1
#=GS M9PJC7_DROME/2004-2046 AC M9PJC7.1
#=GS A0A6J2G1K4_9PASS/976-1019 AC A0A6J2G1K4.1
#=GS A0AAD9F237_DISEL/1131-1174 AC A0AAD9F237.1
#=GS A0AA39LAE9_9BILA/1126-1168 AC A0AA39LAE9.1
#=GS A0A6J1SFR5_FRAOC/1195-1237 AC A0A6J1SFR5.1
#=GS A0A6J0DVB0_PERMB/841-884 AC A0A6J0DVB0.1
#=GS A0A3Q3AS78_KRYMA/1474-1516 AC A0A3Q3AS78.1
#=GS A0A3P9PGS9_POERE/938-980 AC A0A3P9PGS9.1
#=GS H2UVD9_TAKRU/1301-1343 AC H2UVD9.3
#=GS A0AA35JW64_9SAUR/1290-1333 AC A0AA35JW64.1
#=GS A0A8B6DM61_MYTGA/1159-1211 AC A0A8B6DM61.1
#=GS A0A3Q3MRB7_9TELE/1311-1354 AC A0A3Q3MRB7.1
#=GS A0A3Q7NIF6_CALUR/1358-1401 AC A0A3Q7NIF6.1
#=GS A0A8U0P6G0_SALNM/1487-1530 AC A0A8U0P6G0.1
#=GS A0A9P0B0X4_BRAAE/1334-1376 AC A0A9P0B0X4.1
#=GS A0A7J8I4K2_MOLMO/1359-1402 AC A0A7J8I4K2.1
#=GS A0A0L7QPC6_9HYME/503-545 AC A0A0L7QPC6.1
#=GS A0A8C3CRV5_CAIMO/183-226 AC A0A8C3CRV5.1
#=GS A0A2K5IY16_COLAP/1195-1238 AC A0A2K5IY16.1
#=GS A0A8S4B642_9TELE/1465-1508 AC A0A8S4B642.1
#=GS A0A673Y2C5_SALTR/1108-1151 AC A0A673Y2C5.1
#=GS A0A3Q1F7P3_9TELE/926-968 AC A0A3Q1F7P3.1
#=GS A0A6I9X7F6_9SAUR/1327-1370 AC A0A6I9X7F6.1
#=GS A0AA88XN02_PINIB/650-692 AC A0AA88XN02.1
#=GS A0A0V0TIW6_9BILA/1112-1154 AC A0A0V0TIW6.1
#=GS A0A6G1ACF7_CROCR/886-908 AC A0A6G1ACF7.1
#=GS A0A835CV22_APHGI/1569-1611 AC A0A835CV22.1
#=GS A0A384CM96_URSMA/884-927 AC A0A384CM96.2
#=GS A0A670IGR8_PODMU/134-177 AC A0A670IGR8.1
#=GS A0A8C5V233_MICMU/875-917 AC A0A8C5V233.1
#=GS A0A1P6C1H4_BRUMA/1115-1157 AC A0A1P6C1H4.1
#=GS A0AAQ6INL4_ANATE/1608-1651 AC A0AAQ6INL4.1
#=GS A0A8U0P5S0_SALNM/1468-1511 AC A0A8U0P5S0.1
#=GS A0A4W3HMA6_CALMI/308-333 AC A0A4W3HMA6.1
#=GS A0A7K6YP34_ALCTO/921-964 AC A0A7K6YP34.1
#=GS A0A3P8Y433_ESOLU/1486-1529 AC A0A3P8Y433.3
#=GS A0AA39GN76_9BILA/1086-1128 AC A0AA39GN76.1
#=GS A0A4W3HR33_CALMI/193-236 AC A0A4W3HR33.1
#=GS A0A9P0T6I2_PIEBR/1232-1274 AC A0A9P0T6I2.1
#=GS A0A6J0E3B6_PERMB/912-955 AC A0A6J0E3B6.1
#=GS A0A6G0TWJ4_APHGL/1221-1264 AC A0A6G0TWJ4.1
#=GS A0A3Q3LGE5_9TELE/1353-1396 AC A0A3Q3LGE5.1
#=GS A0A663DX80_AQUCH/1320-1363 AC A0A663DX80.1
#=GS A0A1S3R751_SALSA/1574-1617 AC A0A1S3R751.1
#=GS A0A2I4BU43_AUSLI/1390-1433 AC A0A2I4BU43.1
#=GS A0A667HWN7_LYNCA/865-893 AC A0A667HWN7.1
#=GS A0A6J0BNF5_NEOLC/1470-1512 AC A0A6J0BNF5.1
#=GS A0A1S3R8L8_SALSA/1576-1619 AC A0A1S3R8L8.1
#=GS A0A7R8YWS4_HERIL/1433-1475 AC A0A7R8YWS4.1
#=GS A0A2I4CKP7_AUSLI/921-963 AC A0A2I4CKP7.1
#=GS A0A6A5EV89_PERFL/936-978 AC A0A6A5EV89.1
#=GS A0A7K7TN21_9CHAR/2-45 AC A0A7K7TN21.1
#=GS A0A2R8ZVC8_PANPA/1282-1325 AC A0A2R8ZVC8.1
#=GS N6U190_DENPD/206-249 AC N6U190.1
#=GS A0A7M7QR49_NASVI/1533-1575 AC A0A7M7QR49.1
#=GS A0A3P6T1T6_LITSI/931-973 AC A0A3P6T1T6.1
#=GS A0A7R8UV39_HERIL/1429-1471 AC A0A7R8UV39.1
#=GS A0A0A0AI22_CHAVO/912-955 AC A0A0A0AI22.1
#=GS A0A669D6A6_ORENI/900-929 AC A0A669D6A6.1
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A0A673Y9R5_SALTR/1510-1553 ......................sa--QDQQR.ELARRRE.QERR....RR...E..AM.AA..TIDMNFQSDLMAIFEENLF...........
A0A340Y4I9_LIPVE/886-929 .......................l-WLLKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENNFD...........
A0AAD8ZQ03_9TELE/1213-1256 .......................p-TTDQQR.ELARRRE.QERR....RR...E..AM.AA..TIDMNFQSDLMAIFEENLF...........
A0A913XVC0_EXADI/1135-1178 ..................leekkx------M.DRNRARE.AERR....KR...E..AM.AG..TINMNEQSDIMASFEAE--nl.........
A0A8C0FRZ5_BUBBB/1143-1186 ........................SMLDQQR.EMARKRE.QERR....RR...E..AM.AA..TIDMNFQSDLLAIFEENLF...........
A0A9J7LJU7_BRAFL/1364-1406 .......................q-KMAAQR.ERERRKE.QERR....RR...E..AM.AG..GIDMNQQHDIMASFEEM--m..........
A0A3S2UM20_ORYJA/80-122 ........................SSAERAR.EMARKKE.QERR....RQ...E..AM.SG..-FDMTMQWDIMTSFELSLD...........
H3CFD6_TETNG/1338-1381 .......................n-PLDQQR.EIARRRE.QERR....RR...E..AM.TA..TIDMNFQSDLMAIFEENLF...........
A0A8I3NYZ8_CANLF/847-890 .......................l-WLLKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENNFD...........
A0A668ATJ0_9TELE/1338-1381 .......................n-ALDQQR.EMARRRE.QERR....RR...E..AM.AD..TIDINFQSDLMAIFEENLF...........
A0A2Y9M5K8_DELLE/1402-1445 ........................SMLDQQR.ELARKQE.QERR....RR...E..AM.AA..TIDMNFQSDLLSIFEENLF...........
A0AA97KUB1_EUBMA/1287-1330 ........................SMLDQQR.EMARKRE.QERR....RR...E..AM.AA..TIDMNFQSDLLAIFEENLF...........
A0A6P8G7Q8_CLUHA/1504-1547 .....................ald---QQQR.ELLRRRE.QERR....RR...E..AM.AA..MVDMNFQSDLMAIFEENLF...........
G3WFP9_SARHA/923-966 .......................h-RLIKDR.NLARKKE.QERR....RR...E..AM.AS..TIDMNLQSDIMMTFEENLD...........
A0A3Q2C6B9_CYPVA/1297-1340 .......................n-SLDQQR.EIARRRE.QERR....RR...E..VQ.AA..VIDMNFQSDIMAIFEENLF...........
A0A212FH91_DANPL/1277-1318 .....................ppi----SER.DRLRQRE.QERR....RR...E..AL.AG..QIDMNFQSDTMAAFEETL-...........
A0A6P4F2K2_DRORH/2023-2065 .......................d-RAAAKR.AEQRKAE.QERR....RR...E..AM.AG..QIDMNMQSDLMAAFEETL-...........
A0AAF3FK52_9BILA/873-916 .....................lsa---EEERiQMQRLRE.QEKR....KR...E..MM.GN..AIDLTHQMEIMNNFEA---ef.........
A0A6P8Q194_GEOSA/1286-1329 ........................SMLDQQR.EMARKRE.QERR....RR...E..AM.TA..TIDMNFQSDLLAIFEENLF...........
A0A8S4ATW2_9TELE/1483-1526 .......................n-QLDQQR.ELARQRE.RERR....WR...E..AM.AA..TIDMNFQSDLMAIFEETC-f..........
A0A7K9PNW6_9CORV/908-951 ......................hi--LDQDR.NLARKME.QERR....RK...E..AT.AW..IIDVNLQRDIMASFEEYL-e..........
A0A834IM44_RHYFE/1330-1372 ....................sdri----SDR.ERQRLQE.QERR....RR...E..VM.AN..KIDMNMQSDLMAAFEGSL-...........
A0A6P8HQ89_ACTTE/1173-1219 ..............rtkqeerrmm-------.DRNRARE.AERR....RR...E..AQ.AG..TINMNEQSDIMASFEA---dft........
A0A8C8SN98_9SAUR/1223-1266 .......................a-MLDQQR.EMARKRE.QERR....RR...E..AM.AA..TIDMNFQSDLLAIFEENLF...........
A0A2K6P6X4_RHIRO/904-947 .......................l-WLLKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENNFD...........
A0A6J3R5C9_TURTR/1369-1412 ........................SMLDQQR.ELARKQE.QERR....RR...E..AM.AA..TIDMNFQSDLLSIFEENLF...........
A0A7L2IXZ3_9PICI/2-45 ........................SMLDQQR.EMARKRE.QERR....RR...E..AM.AA..TIDMNFQSDLLAIFEENLF...........
A0A673T6G7_SURSU/836-878 ......................ll---LKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENNFD...........
A0A8C7GVN7_ONCKI/1081-1124 .......................t-SVDGER.EMARRRE.QERR....RR...E..AM.SG..VIDMTMQSDIMATFEKNLD...........
A0A2K5ML47_CERAT/908-951 .......................l-WLLKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENNFD...........
A0A195G070_9HYME/1467-1509 .....................dks---AAER.ERLRQRE.QERR....RR...E..AM.AS..QIDMNMQSDLMAAFEESL-...........
A0A6P8XY24_DROAB/2071-2113 .......................d-RAAAKR.AEQRKAE.QERR....RR...E..AL.AG..QIDMNMQSDLMAAFEETL-...........
T1HIB1_RHOPR/1139-1181 ......................dk--AAAER.ERLRQRE.QERR....RR...E..AM.AG..QIDINRQSDLMAAFEETL-...........
A0A3B5QNE5_XIPMA/1517-1560 .......................n-SLDQQR.ELARRRE.QERR....RR...E..VM.AA..TIDMNFQSDLMAIFEENLF...........
A0A9J7LLD6_BRAFL/1354-1396 .......................q-KMAAQR.ERERRKE.QERR....RR...E..AM.AG..GIDMNQQHDIMASFEEM--m..........
A0AAY4E6X7_9TELE/1034-1077 ........................SSVDQQR.EVARKRE.QERR....RR...E..AM.SG..VIDMTMQSDIMSTFEKNLD...........
A0A915IV64_ROMCU/290-332 ......................td--AARQR.ELERELE.QARR....RR...E..AE.DN..PVGITMQMDLMANFEQN--f..........
A0A9J8CU17_CYPCA/1046-1089 ........................SSVDRER.EMARKRE.QERR....RR...E..AM.SG..VIDMTMQSDIMATFEKNLD...........
H2N6S7_PONAB/908-951 .......................l-WLLKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENSFD...........
A0A6P8PB61_GEOSA/1357-1400 ........................SMLDQQR.EMARKRE.QERR....RR...E..AM.TA..TIDMNFQSDLLAIFEENLF...........
A0A6P9AY09_PANGU/1276-1319 ........................SMLDQQR.EELRKQE.QERR....RR...E..AM.AS..TIDMNFQSDLLAIFEENLF...........
A0A673MAX7_9TELE/1035-1060 ........................SSVDRER.EMARKRE.QERR....RR...E..AV.S-..-------------------tl.........
A0AAJ6YLQ3_9HYME/1603-1645 .......................e-KAAAER.ERQRLRE.QERR....RR...E..AM.AG..QIDMNMQSDLMAAFEESL-...........
A0A8S4AVK6_9TELE/1462-1505 .......................n-QLDQQR.ELARQRE.RERR....WR...E..AM.AA..TIDMNFQSDLMAIFEETC-f..........
A0A9P0B2T1_BRAAE/1264-1306 .....................gse---KTER.ERQRLQE.QERR....RK...E..AM.AN..KIDLNMQSDLMAAFEGSL-...........
A0A7J8I4Y7_MOLMO/1326-1369 ........................SMLDQQR.ELARKRE.QERR....RR...E..AM.AA..TIDMNFQSDLLSIFEENLF...........
A0A8C1RP90_CYPCA/1473-1516 .......................s-ALDQQR.ELARRRE.QERR....RR...E..AM.AA..TIDMNFQSDLMAIFEENLF...........
A0A0L0BXS5_LUCCU/969-990 ......................nr-------.-------.----....--...-..--.AG..QIDMNMQSDLMAAFEESL-...........
A0A8C7J483_ONCKI/1447-1490 ......................sa--QDQQR.ELARRRE.QERR....RR...E..AM.AA..TIDMNFQSDLMAIFEENLF...........
A0A7M7JPY1_VARDE/1492-1534 ......................qs---EAER.EKQRRRE.QERR....RR...E..VM.SG..QIDMNAQNDIMTTFEEM--is.........
A0A7J8BNZ6_ROUAE/1084-1127 .......................s-VLDQQR.ELARKRE.QERR....RR...E..AM.AA..TIDMNFQSDLLSIFEENLF...........
U3J474_ANAPP/907-950 .......................h-TLSQDR.NLARKME.QERR....RR...E..AM.AC..TIDMNLQSDVMASFEESL-e..........
A0A452HKW9_9SAUR/1264-1289 ........................SMLDQQR.EMARKRE.QERR....RR...E..AV.SG..-------------------g..........
A0A8J4LAP1_APTPA/919-962 ......................ra--LVQDR.NLARKME.QERR....RR...E..AM.AC..TIDMNLQSDIMASFEEYL-e..........
A0A3Q1JMT7_ANATE/1448-1491 .......................n-PLDQQR.ELARRRE.QERR....RR...E..AM.AA..TIDMNFQSDLMAIFEENLF...........
A0A6J0BNA3_NEOLC/1456-1498 ......................dk--AAAER.ERQRLRE.QERR....RR...E..AM.AG..QIDMNMQSDLMAAFEESL-...........
A0A7K4R3C7_9TYRA/908-951 ......................hi--LDQDR.NLARKME.QERR....RK...E..AM.AW..LIDVNLQRDIMASFEEYL-e..........
A0A3P8ZY22_ESOLU/1576-1619 .......................s-ALDQQR.EVARRRE.QERR....RR...E..AM.TA..TIDMNFQSDLMAIFEENLF...........
A0A6P8PB65_GEOSA/1292-1335 ........................SMLDQQR.EMARKRE.QERR....RR...E..AM.TA..TIDMNFQSDLLAIFEENLF...........
A0A6P8YI28_THRPL/1609-1651 .......................d-NAAAER.ERQRKRE.QERR....RR...E..AM.AG..QIDMNKQSELMAAFEESL-...........
A0A9Y6JFX4_9CICH/1191-1234 .......................n-TLNQDR.ATARREA.QERR....RR...E..AM.AD..TIDINFQSDLMAIFEENLF...........
A0A8C7YFW3_9TELE/1462-1488 .......................n-SLDQQR.ELARRKE.QERR....RR...E..AV.--..-------------------rnsv.......
A0A8I3P2C6_CANLF/1124-1167 ........................SMLDQQR.ELARKRE.QERR....RR...E..AM.AA..TIDMNFQSDLLSIFEENLF...........
A0AA97JD55_EUBMA/903-945 .......................q-NLIIDR.NLARKME.QERR....RR...E..AM.AG..IIDMNMQSDIMATFEETL-...........
A0A7L0R1K1_SETKR/909-952 .......................r-ILDQDR.NLARKME.QERR....RK...E..AT.AW..IIDVNLQRDIMASFEEYL-e..........
A0A9J7LJY2_BRAFL/1363-1405 .......................q-KMAAQR.ERERRKE.QERR....RR...E..AM.AG..GIDMNQQHDIMASFEEM--m..........
A0A8C5H7A1_GOUWI/1546-1589 .......................n-SLDQQR.ELARRRE.QERR....RR...E..AM.AA..TIDMNFQSDLMAIFEENLF...........
BRDT_MOUSE/913-956 .......................l-WLLKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENNFD...........
A0A9J6EJ66_RHIMP/135-177 ......................en--AVSER.ERQRLRE.QERR....RR...E..AM.AG..QIDMNRQSDIMATFEEML-...........
A0A5F9C696_RABIT/862-905 .......................q-QLLKDR.NLAREKE.QERR....RR...E..AM.AG..TIDMTLQSDIMTMFENNFD...........
A0A8C3RB56_9PASS/927-970 .......................h-TLDQDR.NLARKME.QERR....RK...E..AT.AW..IIDVNLQRDIMASFEEDL-e..........
A0A672RYC9_SINGR/957-1000 ........................SSVDRER.EMARKRE.QERR....RR...E..AM.SG..VIDMTMQSDIMATFEKNLD...........
#=GC seq_cons ..........................lsppR.EhAR++E.QERR....RR...E..AM.Au..sIDMNhQSDlMAhFEEsL............
//
