GenomeNet

Database: Pfam
Entry: BslA
LinkDB: BslA
Original site: BslA 
#=GF ID   BslA
#=GF AC   PF17735.3
#=GF DE   Biofilm surface layer A
#=GF AU   El-Gebali S;0000-0003-1378-5495
#=GF SE   Regan L
#=GF GA   38.70 38.70;
#=GF TC   38.70 38.70;
#=GF NC   36.40 24.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0159
#=GF RN   [1]
#=GF RM   23904481
#=GF RT   BslA is a self-assembling bacterial hydrophobin that coats the
#=GF RT   Bacillus subtilis        biofilm.
#=GF RA   Hobley L, Ostrowski A, Rao FV, Bromley KM, Porter M, Prescott
#=GF RA   AR, MacPhee CE, van Aalten DM, Stanley-Wall NR;
#=GF RL   Proc Natl Acad Sci U S A. 2013;110:13600-13605.
#=GF DR   INTERPRO; IPR034650;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family includes members such as BslA (previously called
#=GF CC   YuaB). Secreted BslA from Bacillus subtillis has been shown to
#=GF CC   form surface layers around the biofilm self-assembling at
#=GF CC   interfaces of B. subtilis biofilms, forming an elastic film.
#=GF CC   structural analysis revealed that BslA consists of an Ig-type
#=GF CC   fold with the addition of an unusual, extremely hydrophobic cap
#=GF CC   region. The hydrophobic cap exhibits physiochemical properties
#=GF CC   similar to the hydrophobic surface found in fungal hydrophobins;
#=GF CC   thus, BslA is defined as member of a class of bacterially
#=GF CC   produced hydrophobins [1].
#=GF SQ   28
#=GS A0A559J2J2_9BACL/16-134     AC A0A559J2J2.1
#=GS A0A1B8VX47_9BACI/648-762    AC A0A1B8VX47.1
#=GS A0A4U7JG05_9FIRM/605-724    AC A0A4U7JG05.1
#=GS BSLA_BACSU/50-170           AC P71014.2
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU E; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU F; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU J; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU D; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU C; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU G; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU H; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU B; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU A; 50-170;
#=GS BSLA_BACSU/50-170           DR PDB; 4BHU I; 50-170;
#=GS A0A5J5GC97_9BACL/388-516    AC A0A5J5GC97.1
#=GS A0A318XSH1_9FIRM/604-723    AC A0A318XSH1.1
#=GS A0A229UH76_9BACL/141-259    AC A0A229UH76.1
#=GS Q62P74_BACLD/48-168         AC Q62P74.1
#=GS A0A1I2XFC2_9FIRM/1010-1130  AC A0A1I2XFC2.1
#=GS A0A4R5KRN7_9BACL/1066-1202  AC A0A4R5KRN7.1
#=GS A0A4E0PSV6_9EURY/113-234    AC A0A4E0PSV6.1
#=GS A0A0M2EC80_BACIA/42-162     AC A0A0M2EC80.1
#=GS A0A494XWN1_9BACL/2062-2184  AC A0A494XWN1.1
#=GS BSLB_BACSU/35-154           AC P39632.1
#=GS BSLB_BACSU/35-154           DR PDB; 5MKD D; 35-154;
#=GS BSLB_BACSU/35-154           DR PDB; 5MKD C; 35-154;
#=GS BSLB_BACSU/35-154           DR PDB; 5MKD A; 35-154;
#=GS BSLB_BACSU/35-154           DR PDB; 5MKD B; 35-154;
#=GS C6PZK4_9CLOT/449-572        AC C6PZK4.1
#=GS A0A1V4SMY5_RUMHU/606-725    AC A0A1V4SMY5.1
#=GS W0EBA8_9FIRM/624-737        AC W0EBA8.1
#=GS A5A641_BACLD/44-160         AC A5A641.1
#=GS K4L544_9FIRM/326-447        AC K4L544.1
#=GS S0FIX1_RUMCE/603-722        AC S0FIX1.1
#=GS A0A369BHG2_9FIRM/534-655    AC A0A369BHG2.1
#=GS B8I582_RUMCH/606-725        AC B8I582.1
#=GS F0SUR7_SYNGF/340-462        AC F0SUR7.1
#=GS Q65DE9_BACLD/41-157         AC Q65DE9.1
#=GS A0A327RJG0_9BACI/372-488    AC A0A327RJG0.1
#=GS A0A4Y6UWH8_9BACL/42-160     AC A0A4Y6UWH8.1
#=GS A8FDH5_BACP2/45-165         AC A8FDH5.1
#=GS A0A5J5GC97_9BACL/546-661    AC A0A5J5GC97.1
A0A559J2J2_9BACL/16-134                .......................................i-TVTAITS.dREGA.VT.DILISYRPDAILAL..GAVVFTLPAGFTA.TTTDTL--..NG.--TTLLS..SQ...IS..NNGGRVTLGlTLDL..LGLAQ.FDLLL......KAKPLPAAGT..YRFRA.ENTLLFLGSQGV.---------aetdfavev.....
A0A1B8VX47_9BACI/648-762               ..............................ksflagslqs--------..----.--.MIRFDYITGEAYSN..GILEVSM-EGLTF.NTNDLIFV..NG.-WRNITS..DQ...LS..NDGHTLTIK.NITG..-PSQD.IAFEL......HNKRVPSTGD..YLIRF.RADADGIGTQKSfSEEQ-----qitlr.........
A0A4U7JG05_9FIRM/605-724               ........................................LEINPESG..EAGT.KA.DFELTYTAGDNMSN..GTVVIKLPNGFSA.YVSDTVSI.nGG.SEINLLS..SQ...IP..NL-QTLSFT.NLNL..TKGDK.IIVYM......RNRVVPAGGH..YEFTT.VTDADATGPKMP.ISGQ-----enat..........
BSLA_BACSU/50-170                      ......................................lf--ATITGAskTEWS.FS.DIELTYRPNTLLSL..GVMEFTLPSGFTA.NTKDTL--..NG.--NALRT..TQ...IL..NNGKTVRVPlALDL..LGAGE.FKLKL......NNKTLPAAGT..YTFRA.ENKSLSIGNKFYaEASIDVAKR..............
#=GR BSLA_BACSU/50-170           SS    ......................................EE--EEE-SS--BTTS.EE.EEEEEEE-SSSEEE..EEEEEE--TT---.-TTSEE--..TT.--EE--G..GG...EE..TTTTEEEEEEEEEE..TT-S-.B-EEE......EEEE--SSEE..EEEEE.EEECCEES---EEEEEEEEB-S..............
A0A5J5GC97_9BACL/388-516               ...............................daslaskef--------..TEGS.LS.KIRFDYFPKEAFID..GTLQIDI-EGVSV.TTGDYYSLgdDT.GWTKFTA..DQ...LS..NDGHTVTIT.HINT..AAQND.VSVELggsvfpVGKTIPAAGS..YPITL.RADADGAGAKLPsEEQ------titlv.........
A0A318XSH1_9FIRM/604-723               ........................................LEINPSSG..EAGT.KA.DFELTYTAGDNMSN..GTVVIKLPNGFSA.YVSDTVSI.dGG.AETNLLS..SQ...IP..NI-QTLSFT.NLNL..SAGDK.IIVYL......RNRVVPAGGH..YEFTT.VSDADATGPRLP.VSGQET---at............
A0A229UH76_9BACL/141-259               ............................tgahtkqlnags--------..---T.AA.NIRFDFFPGETIVN..GVMVLNF-EGITV.DTNDQY-N..AG.SWNKYTS..SQ...IS..NGGHTVTLT.GVNR..VSKQD.IAFML......YNKVIPAPGT..YYITC.TIDADGPGNTRT.ES-------vehkia........
Q62P74_BACLD/48-168                    ....................................lysv----ITGAskQEWS.FS.DIELTYRPNSILAL..GTVEFTLPSGFSA.TTKDTV--..NG.--RALTT..GQ...IL..NNGKTVRLPlTIDL..LGIAE.FKLVL......ANKTLPAAGK..YTFRA.ENRVLGLGSTFYaESSIEVQKR..............
A0A1I2XFC2_9FIRM/1010-1130             ........................................LTISPNSG..AAGS.TA.TITVTYTTGDAVD-..-FIYFDNPNEIKA.VGSDKISI.aGG.PEKEIQN..EEsqaTV..DEYGTVEIEpSTPL..GTNDT.IVITL......LNKTLPSVGD..YDFNI.DAYAGEKA----.---------stwesvtfsv....
A0A4R5KRN7_9BACL/1066-1202             elslvdevmtagttrniqvaynvtskvplttsstnhpvfp--------..----.--.-------------K..WEVIFTLPNGIAA.TTADEVSI..VGmDKRKLTS..GE...IS..ANGKIVTLK.ELELqpHNGTD.VLLFL......NAKAVPAVSSqgYEFKA.TNAIQGKDHSV-.---------gaasekav......
A0A4E0PSV6_9EURY/113-234               ........................................LELDPVSA..NNNT.DQ.NIKMVYRAGENITN..GMVRIGIPAEFTVnDTMDTLSV.aNE.PQTTVADnnNA...SY..DANNILTIT.NLTI..NENQE.INLTL......ATRSLDFAGT..YHFTA.GAKNSD------.---------kdisdvisavft..
A0A0M2EC80_BACIA/42-162                ........................................LYAKITGAskQEWS.FS.DIELTYSPNSVLSL..GAVEFTLPKGFQA.TTKDIM--..NG.--KALKD..SY...IL..NNGQTVRIPlRLDL..LGISK.YTLKL......SHKVLPAAGT..YTFRA.ENRAISIGSTFYaEDTIDINTR..............
A0A494XWN1_9BACL/2062-2184             ..................................qvsali------SG..TQGS.-T.DITITETLGEDSLL..GTVTFVLPEGISA.TTQDVVAI.gDE.LPRLLNA..SE...IMpnRNGKYVVVD.GISL..KSGEK.IRLHL......AGKTLPGTS-..AAFRV.YVDSDGPERNYSlSAGTSV---nad...........
BSLB_BACSU/35-154                      ........................................IEAKTVNS.tKEWT.IS.DIEVTYKPNAVLSL..GAVEFQFPDGFHA.TTRDSV--..NG.--RTLKE..TQ...IL..NDGKTVRLPlTLDL..LGASE.FDLVM......VRKTLPRAGT..YTIKGdVVNGLGIGSFYA.ETQLVIDPR..............
#=GR BSLB_BACSU/35-154           SS    ........................................EEEEESS-.-BTTS.EE.EEEEEEE-SS---S..SEEEEE--TT---.-TTSEE--..TT.--EE--G..GG...EE..TTTTEEEEE--HHH..HT-S-.EEEEE......EEEE--SSEE..EEEEEEEESSSS-S---E.EEEEEEB--..............
C6PZK4_9CLOT/449-572                   ........................................ITLSPANG..NRGA.SQ.NIEVIYTPGETMTN..GTVLFTLPEGFSAdLTTDKFKI.aDG.EETALNQ..EE...IG..NNGQTVTLT.DVNA..STSSA.IVLKL......INKTIPDANT..YNFKV.AADSDGLGTAKTwSAGTETES-a.............
A0A1V4SMY5_RUMHU/606-725               ......................................it--LIPASA..EAGTlVN.EFGILYTAGDDMAN..GTVVIKLPSGFSV.FATDTYKI.kDG.EEKALDI..SQ...RP..DI-QTISFT.NLNL..KKGET.IEVRL......KNRHIPSGKT..YEFVA.ISDADGTGPKLP.TSGQE----kg............
W0EBA8_9FIRM/624-737                   ......................................gv------NG..HGGV.VG.ETVLTYTLGEDYNK..GQIEFLLPNGIVA.MEGDLVRI.aNA.EGMGISS..DT...IS..DNGHKVTLT.GVSA..KKDDT.VVLTL......SRDI--EIGR..WDFKV.IGDSDGNGPILQ.---------vqepsit.......
A5A641_BACLD/44-160                    ........................................LEAKTINS.nKEWS.TS.DIEITYRPNAFVGS..SYVEFHFPYRFHA.STRDTL--..NG.--KTLDY..TQ...IL..NDGQTVRVP.-VYA..LSSSE.FKLVM......VRKTLPNAGT..HRITA.ELQQNGKNINHA.ETTLEIVPR..............
K4L544_9FIRM/326-447                   ........................................LSVSPAST..IAGA.TK.NIYLVYLPGENMNN..GTVEFFLPDRYLAiAGQDKITI..NG.TMNSLTS..EQ...IS..DAGRRVKIS.GLNV..TTGQK.IILTL......NDKSVQDVGN..YSFKV.IADADGSGILRP.SSGSLTESR..............
S0FIX1_RUMCE/603-722                   ........................................LSVSPSGG..KAGE.II.DVVITYTAGENMTS..GRIVFKLPAGFTA.SESDTFSI.nSG.AGTALTK..AH...II..DPG-TLSFN.NIAL..AADDT.LQVTL......KKKEIPAGGQ..LEFAA.VVDADGIGPKLPaE--------istift........
A0A369BHG2_9FIRM/534-655               ........................................LSISPQNS..TEGA.ADiDIALIYYPGEALAN..GTVVFSLPSGFRA.QAGDQVKT..NM.GDVDPGQ..VS...YS..GDGSKVTVT.GLYF..SYGEA.VALIL......KERTIPAAGS..YSFYA.TADADGFGTLRTpSAGTGN---er............
B8I582_RUMCH/606-725                   ........................................LEISPVTG..EAAT.VK.DFEITYTSKDDFSN..GTVTFWLPDGFPA.FETDTVKI.gNG.TEVTLNP..SQ...RL..NV-RTLSFT.NLNL..SKGQK.IIVKL......RNKTVPQGGE..YVFSA.VTDADGTGPKVP.TSGQD----ert...........
F0SUR7_SYNGF/340-462                   ........................................LEITPTSS..VNGN.TQ.TVTLTYTLASAMDN..GTLEYVLPAQITAaPELDKIKI.gSG.GEDSLMA..KQ...VL..DEGRKLSIS.GITA..AAGEK.IVLTL......ANKTVPGVGN..YAFRI.FADADGEGDILP.SSGTGKG--ak............
Q65DE9_BACLD/41-157                    ........................................LHVETVDS.nKEWT.TS.DIEVTYKPNFFVGS..SYVEFNFPYRFHA.NTRDSL--..NG.--RTLNY..TQ...IL..NDGQTVRVP.-VYA..FSSSE.FKLVM......VRKTLPNAGT..HRITA.ELQKFGRNYNHA.EATVDILP-r.............
A0A327RJG0_9BACI/372-488               ........................................LRVTPYNG.yVEGT.TT.DVIITYNPKDILML..GSVVFYLPDGFTA.TTYDEL--..NG.--IPLRS..EQ...IS..NDGKTVTLPlSVDL..LGLEE.FKLEL......RSKKLPAADI..YTFKT.ENKPL-------.---------igigganlsgtakl
A0A4Y6UWH8_9BACL/42-160                .....................................vtt---SVPNA..VAGD.TT.DINLAYTNSAVLNLnvGAVDFHLPTGLKA.TTSDQI--..NG.--VNLTP..SQ...IL..DGGQRVRIS.GLSL..TLLQAtSTLSL......KQKTMPVSGN..YNFEV.RVYGLTLT----.---------vinttpsetqta..
A8FDH5_BACP2/45-165                    ........................................LYAKITGTskQEWS.FS.DIELTYRPNSVLSL..GAIEFTLPAGFQA.TTKDIF--..NG.--KALKD..SY...IL..NSGKTVRIPaRLDL..LGISQ.FKLQL......SHKVLPAAGT..YTFRA.ENRALSIGSKFYaEDTLDIQTR..............
A0A5J5GC97_9BACL/546-661               .................................dyfldgd--------..---S.TR.TFILGYQVAPPFDN..GTVTITM-DDFTF.TTSDQYSP..GF.NWSNLTE..EQ...IS..NNGHTLTIS.GIGT..VFDSV.LMVKL......MNKQTPEMGS..SLVRF.VADADGAGGSML.PS-------qeqtatl.......
#=GC SS_cons                           ......................................EEEEEEESSS.-BTTS.EE.EEEEEEE-SSSEEC..CEEEEE--TT---.-TTSEE--..TT.--EE--G..GG...EE..TTTTEEEEEEECCC..CT-S-.EEEEE......EEEE--SSEE..EEEEEEEECCCCES---EEEEEEEEB-S..............
#=GC seq_cons                          ..........................................hps.su..ptso.hs.-IploYpsspshsp..GsVpFsLPsGFsA.sTpDpl....sG...psLss..sQ...I...NsGpTVols.slsl..hsssc.ltLpL......tsKslPuuGs..YpFps.tscusGhGsphs.pst....................
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