GenomeNet

Database: Pfam
Entry: BspA_v
LinkDB: BspA_v
Original site: BspA_v 
#=GF ID   BspA_v
#=GF AC   PF18220.4
#=GF DE   Adhesin BspA variable domain
#=GF AU   Smart A;0000-0002-6965-5633
#=GF SE   ECOD:EUF06990
#=GF GA   25.00 25.00;
#=GF TC   28.40 27.80;
#=GF NC   23.50 22.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   27311712
#=GF RT   Structural and Functional Analysis of Cell Wall-anchored
#=GF RT   Polypeptide Adhesin BspA in Streptococcus agalactiae.
#=GF RA   Rego S, Heal TJ, Pidwill GR, Till M, Robson A, Lamont RJ,
#=GF RA   Sessions RB, Jenkinson HF, Race PR, Nobbs AH;
#=GF RL   J Biol Chem. 2016;291:15985-16000.
#=GF DR   INTERPRO; IPR041237;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This domain is found in BspA protein present in Streptococcus
#=GF CC   agalactiae. BspA is an antigen I/II family polypeptide that
#=GF CC   confers adhesion linked to pathogenesis in group B
#=GF CC   Streptococcus. This domain is referred to as the variable domain
#=GF CC   (BspA-V). BspA-V is responsible for binding to scavenger
#=GF CC   receptor gp340. BspA-V adopts a fold that is distinct from those
#=GF CC   of other AgI/II family polypeptide variable domains [1].
#=GF SQ   9
#=GS A0A3L8GVQ6_STRIN/475-568  AC A0A3L8GVQ6.1
#=GS A0A242K256_9ENTE/147-295  AC A0A242K256.1
#=GS A0A3L8GPT8_STRIN/299-448  AC A0A3L8GPT8.1
#=GS A0A069CTL4_WEIOS/324-473  AC A0A069CTL4.1
#=GS A0A069CX19_WEIOS/86-235   AC A0A069CX19.1
#=GS Q8DX37_STRA5/213-362      AC Q8DX37.1
#=GS A0A242K249_9ENTE/141-296  AC A0A242K249.1
#=GS A0A069D3F2_WEIOS/320-469  AC A0A069D3F2.1
#=GS F9HHP1_9STRE/305-454      AC F9HHP1.1
A0A3L8GVQ6_STRIN/475-568             ..............................AEYGNSIMTVTTQPD.GSFVFK...HDMIDGKKT..IGHGTLTGKINHHYEANKDGSITAYIDSVTFD---------------.---------.-.---------------------------------------------------------------tqvlapfvirdktmlvnkdvnqdnlktfniyg
A0A242K256_9ENTE/147-295             .......................lyitidr--------------S.GKFEFNwtdWDMSGGVITnpMGRGKLTGKINFGMTQENGMTAKWQVRSVTLSNVSYTTLNV-RSLEF.VIKFYVPTI.NgGNLEYERAHNSLTSFSDTLNKTIPINLNGSLGPGQDTGWLQIFTFKDQ---------------glvlssivdgqvkfin................
A0A3L8GPT8_STRIN/299-448             .............................t-EYGNSIMTAKTQAD.GSFEFN...HDMIDGDKT..IGYGKLTGKVNHHYVANKDGSVTAFVDSVTLYKYEYRNVAQNAAVNQ.NIAFRVLTK.D.GQIIFEKKHNGNNTFSETLNKTLDLNLKYDLQPKASSGNVEVFKIHDDWVHDTHGSALVSYVN................................
A0A069CTL4_WEIOS/324-473             ..........................gqyk-----TMMTADVNSEtGEFTLK...HDMNDGNSI..IGQGVLTGKIIFTVVSNGDGTETITVTGIELYKYIYTNLNVNTANNK.NINFHVYDN.N.GNELFSVAHDGQTSFEKDINQTFNLNQSFKLTPGQQSSMFSFLKIADNWIYNTHGQVEIAFTN................................
A0A069CX19_WEIOS/86-235              ..........................gqyk-----TMMTADVNSEtGEFTLK...HDMNDGNSI..IGQGVLTGKIIFTVVSNGDGTETITVTGIELYKYIYTNLNVNTANNK.NINFHVYDN.N.GNELFAVAHDGQTSFEKDINKTFNINQSFKLTPGQQSSMFSFLKIADNWIYNTHGQVEIAFTN................................
Q8DX37_STRA5/213-362                 ..............................AEYGNSIMTAKTKPD.GSFEFN...HDMIDGVKT..IGYGKLTGKVNHHYVANKDGSVTAFVDSITLYKYEYRNVAQNAAVNQ.NIAFRVLTK.D.GQIIFEKKHNGNKTFAETLNKTLQLNLKYELKPHGSSGSVEVFKIHDDWVHDTHGSALVSYVN................................
A0A242K249_9ENTE/141-296             eystpgmsvsidrstgnfvfvwsdwlnasy---------------.------...------TQR..LGRGQVTGKVNFGMGQQSGLNAKWQIRSVTINTCSYTTDNV-SGVNTfVINLYVKDD.S.ETQIYQRTHNAMASFTDSINKTIPISMNGVVTPGTSSGKIQFCEVFNDNTAST----------lddranvqiefvn...................
A0A069D3F2_WEIOS/320-469             ..........................gqyk-----TMMTADVNSEtGEFTLK...HDMNDGNSI..IGQGVLTGKIIFTVVSNGDGTETITVTGIELYKYIYTNLNINTANNK.NINFHVYDN.N.GNELFSVAHDGQTSFEKDINKTFNINQSFKLTPGQQSSMFSFLKIADNWIYNTHGQVEIAFTN................................
F9HHP1_9STRE/305-454                 .............................d-EYGHSFMRGSIS-G.NRFTFT...HDLVDGVGV..IGNGTLTGGLNYRYSVNEDGSIDVELISMYLNTYVYNKTKDNEAVNQ.DISFKIFDQvT.GNLIYVKPHHGANSFTETINKTVPLNIHRRIAPHSSSGYINFIKIHDDWIHDTHGWGAIRF--tn..............................
#=GC seq_cons                        .............................p.....ohMTupsps-.GpFphp...HDM.DGsph..IGpGpLTGKlNaphsuNpDGohThpVsSlpL.pY.Yssls.NsAsNp.sIsF+Vhsp.s.Gs.laphsHsGtsSFpcslNKThslN.phcLsPtppSuhhphhKItDsWlasTHG.s.lta..................................
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