#=GF ID   CBM-like_CFAP184
#=GF AC   PF23449.3
#=GF DE   CFAP184 CBM-like domain
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   AlphaFold prediction
#=GF GA   27.00 27.00;
#=GF TC   28.80 39.30;
#=GF NC   26.30 19.60;
#=GF BM   hmmbuild  HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 90746521 --cpu 8 -E 1000 HMM pfamseq
#=GF TP   Domain
#=GF CL   CL0202
#=GF RN   [1]
#=GF RM   33661892
#=GF RT   Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating
#=GF RT   that connects radial  spoke 3 to dynein g and the nexin link.
#=GF RA   Bazan R, Schrofel A, Joachimiak E, Poprzeczko M, Pigino G, Wloga
#=GF RA   D;
#=GF RL   PLoS Genet. 2021;17:e1009388.
#=GF DR   INTERPRO; IPR056295;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   This entry represents a domain found in Cilia- and
#=GF CC   flagella-associated protein 184 (also known as CCDC96,
#=GF CC   SwissProt:I7M6D6) from Tetrahymena thermophila and similar
#=GF CC   sequences. CFAP184 forms a complex with CFAP263, and acts as a
#=GF CC   regulator of ciliary beating that connects radial spoke 3 (RS3)
#=GF CC   to the inner dynein arm (IDA) and the nexin-dynein regulatory
#=GF CC   complex (N-DRC) [1]. This domain may have a CBM-like
#=GF CC   (carbohydrate-binding module) fold according to structure
#=GF CC   predictions and comparison.
#=GF SQ   18
#=GS A0A8S1SRE8_9CILI/251-365  AC A0A8S1SRE8.1
#=GS A0A8S1KZ72_9CILI/256-370  AC A0A8S1KZ72.1
#=GS A0A078B1C9_STYLE/221-331  AC A0A078B1C9.1
#=GS A0A1R2BGF2_9CILI/182-291  AC A0A1R2BGF2.1
#=GS A0A0V0R9M6_PSEPJ/264-385  AC A0A0V0R9M6.1
#=GS G0R1X6_ICHMU/222-329      AC G0R1X6.1
#=GS A0AAD2D7U8_EUPCR/258-371  AC A0AAD2D7U8.1
#=GS A0BIG5_PARTE/167-281      AC A0BIG5.1
#=GS A0A8S1K0K3_PARPR/251-365  AC A0A8S1K0K3.1
#=GS A0DYC6_PARTE/249-363      AC A0DYC6.1
#=GS G0QTH2_ICHMU/261-367      AC G0QTH2.1
#=GS CF184_TETTS/253-360       AC I7M6D6.1
#=GS A0A8S1SE96_PAROT/249-363  AC A0A8S1SE96.1
#=GS A0A8S1KZ72_9CILI/720-834  AC A0A8S1KZ72.1
#=GS A0A8S1KPP3_9CILI/255-369  AC A0A8S1KPP3.1
#=GS A0A8S1K0K3_PARPR/676-790  AC A0A8S1K0K3.1
#=GS A0A8S1SZV1_PAROT/167-281  AC A0A8S1SZV1.1
#=GS A0A8S1SZT3_9CILI/251-365  AC A0A8S1SZT3.1
A0A8S1SRE8_9CILI/251-365             ...............VTKIEDSNDGCILVHGKMLE........D.....LVGVYALQIL.......P..FSSdsgkvpD......KNENNKIGPEHIEFDRQTKCFVAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
A0A8S1KZ72_9CILI/256-370             ...............VTKIEDSNDGSILVHGKMLE........D.....LVGVYALQIL.......P..FNN......DnakvpdKNENNKIGPEHIEFDRQTKCFIAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
A0A078B1C9_STYLE/221-331             ...............INQLTESEDGGIDVRGMMLS........S.....EVGLYAARVV.......A..IKN......L......KKDIKVVGPANIQFDKNTRTFIINIEGPVENV.-FYSDDPKVLEIYIRKAqIDKIQYSVQ..TQER.VNVAHLELALRLP...............................................................
A0A1R2BGF2_9CILI/182-291             ...............VSKIEKAPE-GILIEGKMLK........T.....DVGVYAVRIV.......E..ITS......M......K-EKAIVGPYSISYDPSTSIFTAIINYPDGIEyGPENRGKNYLEIYVRNN.PETIPYGED..PEEK.VNTKHINLVERM-r..............................................................
A0A0V0R9M6_PSEPJ/264-385             .........ilqvyn-------DQQGFKIRGKILKgqekdkvqK.....DQGLFAVKVV.......KqiADS......L......KEEGRGSGPDKIQYNRNTKEFIVNMD-QHELD.PISQRCEKYLEFYTRLN.PDSIPYGKKsrDSEKpISYKYLEFQLRIP...............................................................
G0R1X6_ICHMU/222-329                 ...............YTRICKPQLNTIEIRGKVLD........Q.....SLGIYAIKVH.......N..LEK......-......NQDIQVIGPEFIEFNKQKQEFKSIFQ----LQ.KEEFNNQNLVDLYMRIM.PDSITYMNNqgNSEN.IQFKHLQIKQRMP...............................................................
A0AAD2D7U8_EUPCR/258-371             ..............i-CKVEGTEDDGARIEGQMIE........NekkefDVGIYAVRVV.......A..LKN......L......KKDFVIAGPPQIEFNEETKNFTIVFEGPLDLF.--YSNDPKMLEFYVRKI.NPPIEYGKP..SDER.INVNYLQIAGRMP...............................................................
A0BIG5_PARTE/167-281                 ...............VTKIEDSNDGSILVYGKMLE........D.....EVGVYALQILpftsdssN..VSD......-......KNENNKIGPEHIEFDRQTKCFIAKIG--NQGQ.PCTYDIRQYIDLYTRKS.PESIPYMKS..TREK.LNLKHVDLKLRIP...............................................................
A0A8S1K0K3_PARPR/251-365             ...............VTKIEDSNDGCILVHGKMLE........D.....LVGVYALQIL.......P..FSSdsgkvpD......KNENNKIGPEHIEFDRQTKCFVAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
A0DYC6_PARTE/249-363                 ...............VTKIEDSNDGSILVHGKMLE........D.....LVGVYALQIL.......P..FTS......DsgkvpdKNENNKIGPEHIEFDRQTKCFIAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
G0QTH2_ICHMU/261-367                 ...............IQKIHEPEPNKLEIYGKMLQ........E.....DLGIYAIRVI.......N..KDD......Q......KKTQKVLV------------------------.-----------------.---------..----.-------------lnlqnitvqlkngqlylkqkiiilkilekrqnfileqpqiqfhirknklktknyhinisklns
CF184_TETTS/253-360                  ...............IQKISQPEQNKIEIRGKMLD........E.....NFGIYAIRIM.......N..VDD......Q......KKDIKGVGPEFIEYTRSTQEWMASFE----LE.-LYNQDRMAIEYYTRVS.PDSIPYKKKqsKNEK.LTYKHLQLRLRTP...............................................................
A0A8S1SE96_PAROT/249-363             ...............VTKIEDSNDGSILVHGKMLE........D.....LVGVYALQIL.......P..FTS......DsgkvpdKNENNKIGPEHIEFDRQTKCFIAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
A0A8S1KZ72_9CILI/720-834             ...............VTKIEDSNDGSILVHGKMLE........D.....LVGVYALQIL.......P..FNN......DnakvpdKNENNKIGPEHIEFDRQTKCFIAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
A0A8S1KPP3_9CILI/255-369             ...............VTKIEDSNDGSILVHGKMLE........D.....LVGVYALQIL.......P..FNN......DnakvpdKNENNKIGPEHIEFDRQTKCFIAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
A0A8S1K0K3_PARPR/676-790             ...............VTKIEDSNDGCILVHGKMLE........D.....LVGVYALQIL.......P..FSSdsgkvpD......KNENNKIGPEHIEFDRQTKCFVAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
A0A8S1SZV1_PAROT/167-281             ...............ITKIEDSNDGCILVYGKMLE........D.....DVGVYALQIL.......P..FTSdsgkatD......KNENNKIGPEHIEFDRQSKCFVAKIG--NQGQ.PCTYDIRQYIDLYTRKS.PESIPYMKN..TRDK.LNLKHLDLKLRIP...............................................................
A0A8S1SZT3_9CILI/251-365             ...............VTKIEDSNDGCILVHGKMLE........D.....LVGVYALQIL.......P..FSSdsgkvpD......KNENNKIGPEHIEFDRQTKCFVAKIG--NQGQ.PCTYDIRQYIDLYTRNT.PESIPYKKS..TREK.LNLKHIELKLRIP...............................................................
#=GC seq_cons                        ...............VTKIEDSNDGsILV+GKMLE........D......VGVYALQIL.......s..hss......p......KNENNKIGPEHIEFDRQTKCFlAKIG..NQGQ.PCTYDIRQYIDLYTRso.PESIPYpKs..TREK.LNLKHlELKLRIP...............................................................
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