GenomeNet

Database: Pfam
Entry: CO_dh
LinkDB: CO_dh
Original site: CO_dh 
#=GF ID   CO_dh
#=GF AC   PF02552.18
#=GF DE   CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit
#=GF AU   Bashton M;0000-0002-6847-1525
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   COGs
#=GF GA   20.70 20.70;
#=GF TC   20.70 20.70;
#=GF NC   20.60 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0085
#=GF RN   [1]
#=GF RM   8662887
#=GF RT   Carbon monoxide dehydrogenase from Methanosarcina frisia Go1.
#=GF RT   Characterization of the enzyme and the regulated expression of
#=GF RT   two operon-like cdh gene clusters. 
#=GF RA   Eggen RIL, van Kranenburg R, Vriesema AJ, Geerling AC, Verhagen
#=GF RA   MF, Hagen WR, de Vos WM; 
#=GF RL   J Biol Chem 1996;271:14256-14263.
#=GF RN   [2]
#=GF RM   8550451
#=GF RT   Characterization of the cdhD and cdhE genes encoding subunits of
#=GF RT   the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex
#=GF RT   from Methanosarcina thermophila. 
#=GF RA   Maupin-Furlow J, Ferry JG; 
#=GF RL   J Bacteriol 1996;178:340-346.
#=GF DR   INTERPRO; IPR003704;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of Carbon monoxide dehydrogenase I/II beta
#=GF CC   subunit  EC:1.2.99.2 and acetyl-CoA synthase epsilon subunit. 
#=GF CC   Carbon monoxide beta subunit catalyses the reaction: CO + H2O +
#=GF CC   acceptor <=> CO2 + reduced  acceptor.
#=GF SQ   142
#=GS A0A1W1I574_9BACT/22-195   AC A0A1W1I574.1
#=GS C6HV33_9BACT/30-190       AC C6HV33.1
#=GS A0A0E3L0V2_9EURY/8-167    AC A0A0E3L0V2.1
#=GS A0A4E0PV43_9EURY/9-167    AC A0A4E0PV43.1
#=GS F4C0K7_METSG/11-182       AC F4C0K7.1
#=GS A8URS1_9AQUI/3-168        AC A8URS1.1
#=GS C0GC10_9FIRM/22-185       AC C0GC10.1
#=GS A0A0J6YVF5_9BACT/23-186   AC A0A0J6YVF5.1
#=GS ACDE_METKA/1-157          AC Q8TXF6.1
#=GS A0A0S4LP20_9BACT/22-192   AC A0A0S4LP20.1
#=GS I0IRF4_LEPFC/25-183       AC I0IRF4.1
#=GS A0A0S4KTY3_9BACT/22-191   AC A0A0S4KTY3.1
#=GS A6UU88_META3/4-166        AC A6UU88.1
#=GS A0A1W1I4N2_9BACT/43-197   AC A0A1W1I4N2.1
#=GS ACDE1_METAC/8-167         AC Q8TRZ5.1
#=GS A0A1M6SB37_9AQUI/20-182   AC A0A1M6SB37.1
#=GS T0XWN4_9BACT/23-182       AC T0XWN4.1
#=GS A6UW78_META3/3-143        AC A6UW78.1
#=GS I0IS76_LEPFC/22-186       AC I0IS76.1
#=GS D3DJK1_HYDTT/19-183       AC D3DJK1.1
#=GS A0A1F2P853_9EURY/11-185   AC A0A1F2P853.1
#=GS A0A1F2P586_9EURY/5-167    AC A0A1F2P586.1
#=GS A0A366MAW6_9EURY/1-168    AC A0A366MAW6.1
#=GS C1DU39_SULAA/20-185       AC C1DU39.1
#=GS O67228_AQUAE/28-192       AC O67228.1
#=GS G7WKY0_METH6/5-176        AC G7WKY0.1
#=GS A0A0S4L4A9_9BACT/22-191   AC A0A0S4L4A9.1
#=GS ACDE2_ARCFU/2-172         AC O30273.3
#=GS ACDE2_ARCFU/2-172         DR PDB; 1YTL B; 17-171;
#=GS ACDE2_ARCFU/2-172         DR PDB; 1YTL D; 17-171;
#=GS ACDE2_ARCFU/2-172         DR PDB; 1YTL A; 17-171;
#=GS ACDE2_ARCFU/2-172         DR PDB; 1YTL C; 18-171;
#=GS A0A2U0S5Q7_9ARCH/2-175    AC A0A2U0S5Q7.1
#=GS Q2FQF8_METHJ/6-174        AC Q2FQF8.1
#=GS A0A2K9EBJ3_9FIRM/27-188   AC A0A2K9EBJ3.1
#=GS A0A133VQM0_9EURY/3-155    AC A0A133VQM0.1
#=GS Q0W882_METAR/2-174        AC Q0W882.1
#=GS I2K9Y3_9PROT/19-185       AC I2K9Y3.1
#=GS L0KWZ4_METHD/8-166        AC L0KWZ4.1
#=GS A0A0S4LJG8_9BACT/21-181   AC A0A0S4LJG8.1
#=GS A0A1F2P981_9EURY/11-169   AC A0A1F2P981.1
#=GS ACDE1_ARCFU/7-181         AC O29164.1
#=GS A0A0S4LHE8_9BACT/31-192   AC A0A0S4LHE8.1
#=GS C1DU52_SULAA/19-183       AC C1DU52.1
#=GS A0A0E3NW84_9EURY/8-167    AC A0A0E3NW84.1
#=GS A0A133VH21_9EURY/1-156    AC A0A133VH21.1
#=GS A0A133VF34_9EURY/1-156    AC A0A133VF34.1
#=GS A0A2V3J7Y3_9EURY/1-185    AC A0A2V3J7Y3.1
#=GS A0A1D3L4C9_9EURY/2-169    AC A0A1D3L4C9.1
#=GS D8PBI3_9BACT/44-198       AC D8PBI3.1
#=GS F6BF45_METIK/5-144        AC F6BF45.1
#=GS A0B5W4_METTP/5-177        AC A0B5W4.1
#=GS A0A165Z8J4_9EURY/1-167    AC A0A165Z8J4.1
#=GS ACDE_METTH/4-171          AC O27744.1
#=GS A0A562S9H4_9DELT/24-185   AC A0A562S9H4.1
#=GS A0A0F7IDL1_9EURY/4-178    AC A0A0F7IDL1.1
#=GS A0A1D2W7Y7_9EURY/1-168    AC A0A1D2W7Y7.1
#=GS A0A133U9T6_9EURY/11-116   AC A0A133U9T6.1
#=GS A0A1F2P2R6_9EURY/7-180    AC A0A1F2P2R6.1
#=GS A0A3M0BIC1_9AQUI/18-183   AC A0A3M0BIC1.1
#=GS J9ZEC3_LEPFM/39-199       AC J9ZEC3.1
#=GS E3GYE4_METFV/2-157        AC E3GYE4.1
#=GS A0A166DE02_9EURY/1-168    AC A0A166DE02.1
#=GS C4FIQ3_9AQUI/19-183       AC C4FIQ3.1
#=GS A0A2V3JNJ2_9EURY/10-166   AC A0A2V3JNJ2.1
#=GS T0XR13_9BACT/24-142       AC T0XR13.1
#=GS I0IRF5_LEPFC/39-203       AC I0IRF5.1
#=GS A0A2U0RWS8_9ARCH/4-178    AC A0A2U0RWS8.1
#=GS A0A0D8IAM4_9CLOT/24-188   AC A0A0D8IAM4.1
#=GS D3DIA0_HYDTT/21-183       AC D3DIA0.1
#=GS A0A2V2N613_9EURY/7-174    AC A0A2V2N613.1
#=GS A0A1M6TGC0_9AQUI/552-726  AC A0A1M6TGC0.1
#=GS N0BI82_9EURY/2-173        AC N0BI82.1
#=GS A0A177QHS2_9BACT/43-195   AC A0A177QHS2.1
#=GS A0A4C1WX79_EUMVA/108-223  AC A0A4C1WX79.1
#=GS W9DTU2_METTI/5-167        AC W9DTU2.1
#=GS A0A133UGI6_9EURY/15-110   AC A0A133UGI6.1
#=GS A0A1Q6DUX4_9EURY/4-111    AC A0A1Q6DUX4.1
#=GS A0A133VET1_9EURY/3-152    AC A0A133VET1.1
#=GS O67252_AQUAE/19-183       AC O67252.1
#=GS F2KT92_ARCVS/7-159        AC F2KT92.1
#=GS A0A133UUD4_9EURY/1-157    AC A0A133UUD4.1
#=GS A0A330L3J0_9BACT/22-194   AC A0A330L3J0.1
#=GS A0A177Q8F3_9BACT/22-180   AC A0A177Q8F3.1
#=GS A0A0K2G932_NITMO/43-196   AC A0A0K2G932.1
#=GS B1I5X8_DESAP/23-188       AC B1I5X8.1
#=GS A0A497XQP2_9AQUI/18-183   AC A0A497XQP2.1
#=GS L0HDF9_METFS/1-174        AC L0HDF9.1
#=GS D8PBX5_9BACT/22-117       AC D8PBX5.1
#=GS A0A2C6MBJ6_9FIRM/24-186   AC A0A2C6MBJ6.1
#=GS D3SNX7_THEAH/561-726      AC D3SNX7.1
#=GS A8UTN3_9AQUI/557-728      AC A8UTN3.1
#=GS G7WQP4_METH6/5-176        AC G7WQP4.1
#=GS A0A4Q3E4U7_9RICK/1-38     AC A0A4Q3E4U7.1
#=GS O67557_AQUAE/619-788      AC O67557.1
#=GS B4U665_HYDS0/21-186       AC B4U665.1
#=GS M1Z137_NITG3/23-184       AC M1Z137.1
#=GS I2KA06_9PROT/19-183       AC I2KA06.1
#=GS F0T9G7_METLA/1-168        AC F0T9G7.1
#=GS A7I829_METB6/1-175        AC A7I829.1
#=GS F2KTA2_ARCVS/6-176        AC F2KTA2.1
#=GS A0A2V3JP39_9EURY/3-163    AC A0A2V3JP39.1
#=GS A0A2V3JRY2_9EURY/14-114   AC A0A2V3JRY2.1
#=GS A0A0S4KN86_9BACT/52-203   AC A0A0S4KN86.1
#=GS I0IS74_LEPFC/23-185       AC I0IS74.1
#=GS D3DJP9_HYDTT/551-727      AC D3DJP9.1
#=GS A0A133V8E3_9EURY/3-154    AC A0A133V8E3.1
#=GS B1I1E9_DESAP/5-180        AC B1I1E9.1
#=GS A0A177QA95_9BACT/16-185   AC A0A177QA95.1
#=GS A0A1V6N5A4_9EURY/1-169    AC A0A1V6N5A4.1
#=GS ACDE_METBU/8-168          AC Q12XL6.1
#=GS D7E801_METEZ/8-168        AC D7E801.1
#=GS U6EBR4_9EURY/2-169        AC U6EBR4.1
#=GS C4FIH7_9AQUI/19-181       AC C4FIH7.1
#=GS D3RWN9_FERPA/4-178        AC D3RWN9.1
#=GS ACDE2_METAC/9-167         AC Q8TJC5.1
#=GS A0A0E3NUM5_9EURY/8-167    AC A0A0E3NUM5.1
#=GS D3SQJ0_THEAH/19-183       AC D3SQJ0.1
#=GS B4U695_HYDS0/494-667      AC B4U695.1
#=GS F7XMA1_METZD/13-174       AC F7XMA1.1
#=GS C6HUY7_9BACT/22-186       AC C6HUY7.1
#=GS ACDE_METJA/4-144          AC P81332.1
#=GS A0A0K2G8I3_NITMO/22-195   AC A0A0K2G8I3.1
#=GS A0A497XSR2_9AQUI/23-185   AC A0A497XSR2.1
#=GS A0A1M6S155_9AQUI/19-183   AC A0A1M6S155.1
#=GS Q6LYK7_METMP/3-170        AC Q6LYK7.1
#=GS A0A133UIV2_9EURY/78-173   AC A0A133UIV2.1
#=GS A0A330L2K1_9BACT/44-198   AC A0A330L2K1.1
#=GS D5EBX1_METMS/8-167        AC D5EBX1.1
#=GS A0A0S4L8E4_9BACT/43-197   AC A0A0S4L8E4.1
#=GS B4U6S5_HYDS0/19-183       AC B4U6S5.1
#=GS C6HUZ5_9BACT/23-186       AC C6HUZ5.1
#=GS A0A133UCH0_9EURY/11-116   AC A0A133UCH0.1
#=GS A8V491_9AQUI/19-183       AC A8V491.1
#=GS A0A497XN64_9AQUI/557-729  AC A0A497XN64.1
#=GS A0A0S4LAA9_9BACT/43-192   AC A0A0S4LAA9.1
#=GS D3SQ60_THEAH/22-184       AC D3SQ60.1
#=GS A0A062VAK5_9EURY/10-175   AC A0A062VAK5.1
#=GS A0A0J6YXM9_9BACT/23-185   AC A0A0J6YXM9.1
#=GS A0A133UV11_9EURY/1-157    AC A0A133UV11.1
#=GS F8ADR8_THEID/370-536      AC F8ADR8.1
#=GS R5KHL0_9BACT/182-256      AC R5KHL0.1
#=GS A8UW23_9AQUI/23-185       AC A8UW23.1
#=GS M1Z2F6_NITG3/23-185       AC M1Z2F6.1
#=GS J9ZG37_LEPFM/21-186       AC J9ZG37.1
#=GS A0A0J6YUB3_9BACT/23-186   AC A0A0J6YUB3.1
A0A1W1I574_9BACT/22-195              ........................................................gvyl------P.....NPGEAHINGVI.ASE..E.KA....YEEAARQFLMASVPTIFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......ATA.I.R.....HLYNTLKEcvq........pgqkAMLIPM..P..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.K..IDCCMFVGVHCHQANLSLKIIRGGT..SCYTIAMCAQAGHEDAML..SFRDAS.VEK.I----------mtladwikklk....................................................
C6HV33_9BACT/30-190                  ..............................................pepgygnvegrplp-------.....-----------.--E..E.EV....LETSARALASARVPTFFPGPMVL..W....Q...FS..E.....ES.....R.....R.....V.......ADA.V.L.....SVAESNGI...............-RIIPM..P..D...YR.P...K.Y....PKIDPETEINPNHPNLTIWHN.K..IDVCLFVGVHCHYSNIALKIIRGGT..ACRTIALCSFAGDEEADI..TVRDLS.AEK.ILE--------lgrlirkm.......................................................
A0A0E3L0V2_9EURY/8-167               ................................................tklftsygvtts-------.....-----------.-KA..I.NP....-DMAAKMISKAKRPLFVVGTGVL..Q....P...EL..L.....DR.....A.....V.....K.......IAK.K.A.....NLPIAATGs.............sLPGFLD..K..D...VD.A...S.Y...iNLHQLGFYLTDPKWPGLDEKG.N..YDMVIVLGFKKYYINQVLSGTKNFS..-SVKAISIGRDYIQNATM..SFGNIS.KED.--NYAALDEL-i..............................................................
A0A4E0PV43_9EURY/9-167               ....................................................miyttwgr-------.....---------KT.AKP..M.NP....-NVGGKMILKAKRPLLVVGSEIV..G....N...EI..L.....TE.....K.....T.....I.......AIA.K.K.....GIQVAATG...............HSITVFngK..D...VG.A...K.Y...iNVHALAHYLGDKKWSGLDGQG.P..YDAILFLGHKKYYLDQVLSGLKNFT..-DLKTIAIERHFMQNATW..SFGNLK.PEV.--HLEALDEF-i..............................................................
F4C0K7_METSG/11-182                  ..........................................................tt--KNPIP.....FEMAQIPGPEM.AKT..Y.LP....-KVIGAIIRKAKRPLLVVGAELF..D....D...PV..M.....FD.....K.....M.....I.......EMG.K.M.....GIPIAATAhs..........vkgFVDRGY..L..-...-E.N...V.Yq..iGLHPLTNFLRFPDWKGLDGQG.Q..YDVVIFLGIYYKFANGMLSTLKNFN..RDIKRVSIDRYYHVNADM..TFGNLA.FNP.DDYHAAVDEV-i..............................................................
A8URS1_9AQUI/3-168                   ........................................................edil---TPPP.....--GKALLFNEI.VDE..E.VA....MREAAKAMLTRENATIFPGPQVL..Y....A...WN..E.....EA.....K.....E.....K.......AKL.V.R.....RIAETLNA...............-KIIPM..Y..D...YR.P...K.Y....PKIDPEKEINPNHPNLTIWHN.N..IKACIFVGVHCHYANVALKIIRAET..DCFTIALCGNAGHEDAMI..TLRDQH.TEE.LEKFIRVAEE-v..............................................................
C0GC10_9FIRM/22-185                  .......................................................skgvt-----LP.....DEGLALVEGTI.VPE..K.DA....IEKIAEKILQAKNPFFFPGPLLL..W....D...WK..E.....GV.....A.....Q.....K.......AAL.V.K.....KLAEVAGI...............-KIIPM..P..D...YR.P...K.Y....PMINPDIEINPNHPNLTIWHN.K..IDLCLFIGVHCHYANVALKIIRGGT..DCYTIALCGEAGHEDAMI..SLRDVG.LAQ.-----------lealieav.......................................................
A0A0J6YVF5_9BACT/23-186              ...................................................qpekgsgyq-------.....-----LVEGEH.VPE..D.KA....IETLATKLLTLRNPTLFPGPLIV..W....G...WN..K.....EA.....E.....H.....K.......AEL.S.L.....KLAEEVPG...............MNIIPM..P..D...YR.P...I.Y....PKIDPEAVINPCHPNLTIQHN.K..IKVCTFIGVHCHFANITLKMIRANT..NCYTMALCQYDGHEDALL..SIRDLD.SAK.LEK--------iidtikr........................................................
ACDE_METKA/1-157                     ....................................................mplprdpt-------.....-----LIYTDK.AEV..A.RA....-PVLKMVFRRANDSLMIVGPRAV..E....D...EE.wR.....EL.....L.....M.....K.......LRE.E.F.....RMSAVCTA..............pYKGNDL..-..-...-G.R...K.M....GIVEAATLLQRDAPVLGV---.H..PDLVVFTGSRTDVTDRVLQGLRHAR..PDLVKVSLNPEYCPSADY..SLPTVK.RDQ.--FLQELK---alv............................................................
A0A0S4LP20_9BACT/22-192              ........................................................girl------P.....NPGEAHINGVI.APE..E.KA....YEEAARQFLMAKVPTIFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......ATA.V.R.....HLFNTLIEcaq........pgqkPMLIPM..P..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.R..IDCCMFIGVHCHQANLSLKIIRGGT..SCYTIAMCAQAGHEDAML..SFRDAS.VEK.IMKL-------adtvk..........................................................
I0IRF4_LEPFC/25-183                  ...............................................lpdpgeghiegvl-------.....-----------.VPE..I.QA....IEEAARRLSKAKVPTFFPGPLVL..W....K...WN..E.....KS.....A.....K.....M.......AKV.I.K.....R-ASVEGG...............INIIPM..T..D...YR.P...K.Y....PKIDPETEINPNHPNLTIWHN.K..IDACLFVGVHCHQANLALKIIRGGT..DCFTMAFCSFSGHEDANL..SVRDTS.PET.---FELLT---dfl............................................................
A0A0S4KTY3_9BACT/22-191              ........................................................girl------P.....NPGEAHINGVI.VPE..D.QA....YEEAARQFLMAKVPTIFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......ATA.I.R.....HLFETLKEcvq........pgqkPMLIPM..P..D...YR.P...K.Y....PKINPEIEINPNHPNLTIWHN.K..IDCCMFIGVHCHQANLSLKIIRGGT..SCYTIAMCAQAGHEDAML..SFRDAS.VEK.IM---KL----aetv...........................................................
A6UU88_META3/4-166                   .........................................................wnp-------.....----ALSSPNQ.AII..C.SP....-KIAALTIKQSKNPMFVMGSLLNviP....E...EI..A.....EY.....A.....I.....K.......IAK.L.K.....HMTVVSTGg............snIMLSKL..N..-...FK.P...H.Yn..iGAVELINHLKDSNWNGFCGKG.N..YDLICFIGVPYYIGSQGLSTLKNFA..PHLKTITLCKFMHPNADL..SYPNMS.YDG.--WVIYLSKL-v..............................................................
A0A1W1I4N2_9BACT/43-197              .......................................................lepne-------.....-----------.---..E.KV....IEEMARKMLTSPNATIFPGPLLL..W....A...WN..D.....HA.....V.....E.....K.......AKA.T.L.....EIAAQIPE...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFIGVHCHYANLTLKMIRAGT..NCCTMAICAEQGHEDAML..TIRDSD.TAK.-----------ikrvaqifkkvree.................................................
ACDE1_METAC/8-167                    ..................................................tklftsygvs-------.....----------T.SKT..V.TP....-EIAAKLISKAKRPLLMVGTLTL..D....P...EL..L.....DR.....V.....V.....K.......ISK.T.A.....NIPIAATGs.............sLASLAD..K..D...VD.A...E.Y...iNAHMLGFYLTDPNWPGLDGNG.N..YDTVIVLGFKKFYINQVLSAAKNFS..-NLKTIAIERGYIQNATM..SFGNLS.KAD.--HYAALDEL-i..............................................................
A0A1M6SB37_9AQUI/20-182              ........................................................gvel----PPP.....--GKALLYGEI.VDE..E.VA....MREAAKALLTRRNPTIFPGPLVL..W....G...WN..A.....AA.....M.....E.....K.......AKA.V.L.....ELAMEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.K..IEVCIFVGVHCHYANLSLRMIRAGT..NCFTIALCAEMGHEDAMV..SLRDVH.AEE.IRKFK------dvv............................................................
T0XWN4_9BACT/23-182                  .....................................................vvlpdhg-------.....---HGLLMGDV.VPE..E.RA....IEAAARKIAGSRNPTIFPGPLVL..W....K...ST..S.....DS.....V.....R.....M.......AKA.V.L.....ELAR-AGD...............MKIIPM..A..D...YR.P...K.Y....PKINPEEEINPSHPNLTIWHN.R..IDVCLFVGVHCHYSNIALKIIRGGT..DCFTIALCSYAGDDEAHL..TIRDLT.PET.VER--------laas...........................................................
A6UW78_META3/3-143                   ..........................................................gk----TTP.....YQPTAGTNLNH.AEI..V.ST....-KLALSMIKRSKNPILIIGSKEE..Y....N...N-..-.....--.....-.....-.....-.......NLL.D.L.....NIETIHTP...............------..-..-...-K.D...M.N....LLLAMKKVIEQ----------.G..NDLVIFSNITYYYLAQSITHLKHFS..-NATTLTLDRYYNPNAHY..SFPNME.ENE.H----------kesikrlimlyke..................................................
I0IS76_LEPFC/22-186                  ........................................................gvtl------P.....VEGQGSILGLR.VFE..D.QA....IEEAARQLAHAKVPTIFPGPLVL..W....G...WN..A.....QA.....I.....E.....M.......ANA.V.A.....HVAETCGI...............-NIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTIWHN.K..IDVCLFVGVHCHYSNLALKIIRGGT..GCYTIALCNFAGDEEANL..TIRDLT.SEK.IL---------kigeniqkm......................................................
D3DJK1_HYDTT/19-183                  .........................................................gvl---NPPP.....--GKALMFNEI.VDE..D.IA....MREAAKAMLTRQNPTIFPGPQVL..Y....A...WN..E.....EA.....K.....E.....K.......AKL.V.R.....KMAEVLGA...............-KIIPM..Y..D...YR.P...K.Y....PKINPAVEINPNHPNLTIWHN.K..IKACIFVGVHCHYANVALKIIRAET..DCFTIAMCGMAGHEDAMI..TLRDQH.LEE.MEKFIKIAEEV...............................................................
A0A1F2P853_9EURY/11-185              ........................................................spqn----YIS.....FDVGNTHGPES.GRL..A.AP....-EAIGRLIKSAKRPLLIVGSEIL..E....D...DG..M.....LD.....R.....A.....I.......AIG.K.K.....GIPIAATGpa..........irgFVEREY..D..G...EV.Y...Y.Y....QLHELTNCILDPEWKGLDGQG.N..YDVVVFFGIIYYYASAMLSAIKNFGtdPLIRGVSIDKYYHPHARM..TFGNYS.PKRqAEYLEMLDKL-i..............................................................
A0A1F2P586_9EURY/5-167               ...........................................wktgdvpggyistkvdg-------.....-----------.---..-.--....-ATAGRIIKGAKNPLLIVGKLAC..NidfgD...KR..L.....ID.....Y.....A.....I.......EMT.K.R.....GIPTVATAgss.........reyP-----..E..D...IE.I...K.I...mGAVEIVNRLQNPEY-GING-K.P..HDLVITMGIQYYLASQSLSTLKNFA..PHLKTLALCARSHPNATW..AFPYMP.DDA.-----------wkremdilme.....................................................
A0A366MAW6_9EURY/1-168               ..........................................................mn--DRVIP.....WQPTVIAGPKQ.ALL..A.TP....-ETAKLMLKKAKRPLFVVGPYAK..N....E...PL..M.....SH.....V.....K.....E.......IAE.I.W.....DLPIVTTAdt..........fksFHDNGI..E..-...-S.D...S.Y....GIVEIANLLKDPEWEGIKGEG.Q..NDLVLFVGCIYYIASQGLSTLKHFA..PHLKTLTICKYFHSNADA..SFPNMK.DEE.--WEKYLTKM-k..............................................................
C1DU39_SULAA/20-185                  ......................................................valpsa------P.....--NKGLLYGEE.VDE..E.VA....MREAAKAMLTRQNPTIFPGPKIL..W....G...WS..P.....SA.....F.....E.....E.......ADA.I.L.....ELAKEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.R..IEACIFVGVHCHYANLSLRMIRAGT..NCFTIAICGELGHEEAHA..TIRDAH.GEK.IRKFKD-----iliev..........................................................
O67228_AQUAE/28-192                  ........................................................gcdl----PPP.....--GKALLYGEI.VDE..E.VA....MREAAKALLTRRNPTIFPGPLVL..W....G...WN..A.....DA.....M.....E.....K.......AKA.V.L.....ELAMEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.K..IEACIFVGVHCHYANLSLRMIRAGT..NCFTIALCAEMGHEDAMV..SLRDVH.ADE.IRKFR------dvvve..........................................................
G7WKY0_METH6/5-176                   .........................................................ttk---NAVP.....FEMAQIPGPEM.AKA..Y.NT....-AVIGAIIKKAKRPLLVVGAELF..E....D...PV..M.....FD.....K.....A.....I.......AIG.K.T.....GVPIAATAhs..........ikgFVERGY..T..E...NV.T...M.I....GLHPLTNYLRFKDWQGLDGKG.Q..YDVVIFTGIFYKFASAMFSTLKNFN..RDIKRVSIDRYYHVNADM..TFGNLA.FDP.EKYHEAVDEV-i..............................................................
A0A0S4L4A9_9BACT/22-191              ........................................................girl------P.....NPGEAHINGVI.TSE..D.KA....YEEAARQFLMAKVPTIFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......ATA.V.R.....HLFNTLKEcvq........peqkPMLIPM..P..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.K..IDCCMFIGVHCHQANLSLKIIRGGT..SCYTVAMCAQAGHEDAML..SFRDAS.VEK.-----------imrladtv.......................................................
ACDE2_ARCFU/2-172                    ...........................................................a-KALEQP.....FDVANIPGPKM.ATL..L.EK....GKPVANMIKKAKRPLLIVGPDM-..T....D...E-..M.....FE.....R.....V.....K.......KFV.E.K.....DITVVATGsa..........itrFIDAGL..G..-...-E.K...V.Ny..aVLHELTQFLLDPDWKGFDGQG.N..YDLVLMLGSIYYHGSQMLAAIKNFA..PHIRALAIDRYYHPNADM..SFGNLW.KKE.EDYLKLLDEIL...............................................................
#=GR ACDE2_ARCFU/2-172         SS    ...........................................................X-XXXXXX.....XXXXXXXXXX-.-EE..E.--....SHHHHHHHHHSSSEEEEE-S---..-....H...H-..H.....HH.....H.....H.....H.......HHH.T.S.....SSEEEEETTH..........HHHHHHTT-..G..-...-G.G...S.EE..E-HHHHHHHHHSTT--TTTSS-.-..-SEEEEES--HHHHHHHHHHHHHH-..TT-EEEE-SSS--TTSSE..EE---G.GGH.HHHHHHHHHHH...............................................................
A0A2U0S5Q7_9ARCH/2-175               ......................................................sakaes-------.....WQTAEIAGPTK.ANV..I.VK....PEIAAAMVKRAKRPILIVGYLST..K....T...DK..D.....TG.....K.....MieyaiR.......MNK.A.S.....GIPIVATAht..........ikeFVKQGF..N..D...AT.Q...M.N....AM-DIGNRLKDSTWNGLDGKG.P..YDIALFMGLPFYMEFVILAGLKHFS..TNLKTISLDRYYNPHASW..SFPNLK.AEE.--WNQSF----etii...........................................................
Q2FQF8_METHJ/6-174                   .......................................................swira-------.....----EMGGTKQ.ASV..I.SK....PEVLMALLKKAKRPLIIIGHETI..S....D...RV..R.....TD.....IlirmvS.....E.......FQK.T.Q.....RIPILTTShi..........agqVMERGI..R..-...LS.G...V.L....GSMEIIDRLRDPTWNGCDGNG.Q..YDLVFIAGFSYALGSLLFSALKQNA..PQTKVISLDPKYHPHATW..SYANMK.TDS.-----------wkaeidrli......................................................
A0A2K9EBJ3_9FIRM/27-188              ............................................lpekgeslvegcvlpe-------.....-----------.---..T.DG....MKKAAEKLLSAKNPVFVPGPLIL..W....N...WM..D.....GV.....E.....E.....K.......AKA.F.I.....ELANTVGA...............-KIIPM..P..D...YR.P...K.Y....PKIEPEVELNPIHSNLTIMHH.N..IDVCVFAGVHSHYANIALKLIRGGT..SCYTISLSTETGNEDAMI..SIRDVD.AAK.IRQLTEI----tknm...........................................................
A0A133VQM0_9EURY/3-155               ........................................................gett-------.....------SGSKS.AID..L.KP....-KAAGKLLARAKSVLFILGSDLN..E....Y...P-..P.....KT.....I.....K.....K.......IIK.K.A.....NSIIVETGs............akASDIGI..E..-...AN.S...R.Y....GIVEVVDLLCSDD----GWRG.R..YDYIVFVGVPYHIESRMLSGLRLCN..-VGSTITLNRRHQQYADF..SFPNIL.RPK.-FW--------ekslkeia.......................................................
Q0W882_METAR/2-174                   ........................................................aile------P.....WQIAEISGPRK.AAA..I.SK....PEVVVAMIKRSKRPVMIIGHLAA..E....I...--..A.....AG.....D.....R.....KlldylidLGN.T.K.....NIPIIATGht..........nrnLVSRGY..T..-...--.K...A.Ti..lPAVEAAHRLADSGWQGLDGKG.P..HDLAFFAGLPYYLEWTILSGLKHFA..PHVRTVSLGNGYQPHAGY..SFASIP.TEQ.--WLESLKA--vi.............................................................
I2K9Y3_9PROT/19-185                  ........................................................amgv----ELP.....KEGEALLYGNV.VTP..E.EA....MRDAARALLTRDNPTIFPGPQVL..W....D...WK..D.....DV.....A.....E.....K.......AAA.I.L.....DLASEIPN...............CKIIPM..P..D...YR.P...K.Y....PKIDVKAEINPNHPNLTILDN.R..IKACIFVGVHCHYANLSLRMIRAGT..DCYTTALCAYMGHEEAMA..SIRDLH.ASD.IQKFKE-----ivie...........................................................
L0KWZ4_METHD/8-166                   .....................................................tmiyttw-------.....-------GTRN.AKP..V.QP....-LVAAKLISKAKRPLLVVGADVL..E....S...D-..V.....LS.....K.....A.....I.......ELG.K.K.....GMQIAATG...............HSMQGF..KdqD...VN.A...K.Y...iNIHFLATYLGDKTWKGLDGLG.P..YDLLIFLAHKKYYLNQVLSGLKNFT..-DIKTLAIDRHYFQNADM..SFGNLK.PDD.--HLAALDEL-i..............................................................
A0A0S4LJG8_9BACT/21-181              .......................................................rgvvg------P.....SKDEGLVMGKR.VPE..Q.QA....IDEAARRLFQARNPTIFPGPLVL..W....A...WN..Q.....RA.....I.....R.....E.......SEV.V.R.....ALAEAVPA...............-KLIPM..A..D...YR.P...K.Y....PKIVAEKEINPNHPNLTIWKN.K..IDVCLFVGVHCHQSNIALKIIRGGT..DCFTIALCTFSGDDEAHI..TIRDLT.ADT.-----------iqrivd.........................................................
A0A1F2P981_9EURY/11-169              ..................................................pggylsthid-------.....-----------.---..-.--....GATAGRMIKEAKNPLLIVGGLAR..KidlgG...KR..L.....ID.....Y.....A.....I.......EIT.K.K.....GIPTVATAg.............sS-KEYP..E..D...VDiK...M.M....GAVEIVNRLQNPEYG--VNGK.P..HDLVITMGIQYYLASQSLSTLKNFA..PHLKTIALCARNHPNATW..AFPYMP.DYK.--WKEELEKL-lekl...........................................................
ACDE1_ARCFU/7-181                    ...........................................................a-KEEKFPta.krFDIADIQVSRE.ATA..V.KP....-KVVANMIKRAKRPLLVTGGQLL..K....D...EK..L.....VE.....F.....A.....V.......KFA.E.K.....GIPIAATAgs..........skpLIERGI..K..P...VS.K...T.Y....TLHQITQFLQDEEFQGFDGNG.N..YDTVIFLGFLPYYLSRMLSSLKHFS..-KITTIAIDEFYQPHAKF..SFTNLT.KDR.ELYYSMLQEVL...............................................................
A0A0S4LHE8_9BACT/31-192              ....................................................thpdsgfg-------.....-----LCYGQH.APA..D.EV....IAESARQLYTRKNPTIFPGPLYL..W....A...WN..P.....DW.....I.....A.....K.......GQA.L.L.....RLAAEIPN...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEGINPNHPNLTIWHN.K..IEVALFIGIHCHYANLALRMIRAGT..NCLT-IAFCHDIHEDAML..SLQDLD.VT-.-----------ymnhvieifra....................................................
C1DU52_SULAA/19-183                  ........................................................fvln----PPP.....--GKALLFDEI.VDE..E.IA....MKEAAKAMLTRENPTIFPGPQVL..Y....A...WS..E.....DA.....K.....K.....K.......AKL.I.K.....ELANVLGA...............-KIIPM..Y..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.N..IKACIFIGVHCHYANVALKIIRAET..DCFTIAMCSMEGHEDAMI..TLRDQH.PEE.LEKFIEIAK--qv.............................................................
A0A0E3NW84_9EURY/8-167               .................................................tkvftsygvtt-------.....-----------.SRT..V.TP....-AVAAKMIAKAKRPLLVVGTAAA..E....Q...GL..L.....ER.....I.....I.....S.......ISR.T.L.....NLPIAATGs.............sMPAFVG..K..D...VD.A...R.Y...iNLHALGFYLPDPEWPGLDGNG.S..YDTLIVLAHKKYYINQVLSGLRNFS..-SIKTIAIDRNYIQNASV..SFGNLG.KKE.--HIEALDEL-i..............................................................
A0A133VH21_9EURY/1-156               ........................................................mpdp-------.....YMYGETSGRKK.ATE..L.RA....-EALGNMLNSAENVLFVLGSELG..E...yP...ENtlK.....EI.....I.....S.....K.......IEA.T.V.....YKTEAAGA...............-EDFDI..E..-...AE.V...R.L....GLMEIVQRLCD------YLAE.E..FDYIIFVGIPYHIETRVLSGLRSYD..-VKTVVTLNWRHQQYADF..SFKNIS.EKD.-EWKK------elkth..........................................................
A0A133VF34_9EURY/1-156               ........................................................mpdp-------.....YMYGETSGRKK.ATE..L.RA....-EALGNMLNSAENVLFVLGSELG..E...yP...ENtlK.....EI.....I.....S.....K.......IEA.T.V.....YKTEAAGA...............-EDFDI..E..-...AE.V...R.L....GLMEIVQRLCD------YLAE.E..FDYIIFVGIPYHIETRVLSGLRSYD..-VKTVVTLNWRHQQYADF..SFKNIS.EKD.-EWKK------elkth..........................................................
A0A2V3J7Y3_9EURY/1-185               ........................................................mvkm----EIA.....FDVANIPGPDT.GEV..V.SP....-EVVGRYISRARRPLLVVGSEIL..R....D...EF..F.....IQ.....I.....A.....I.......DIG.K.K.....GIPIAATGhsirgfvergydgggEGGDGV..S..V...SV.R...Y.Y....NLHELTNCLRDPNWRGLDGQG.S..YDVVIFFGIVYYYASQMLSCIKNFAiePLIRTVSIDRYYHPHARM..SFRNIP.PNR.EEEYKALLK--rvv............................................................
A0A1D3L4C9_9EURY/2-169               ...........................................................s-KERVIP.....WQPTVIAGPKQ.ALL..V.TP....-ETAKMMIKKSKRPLMVVGPLVK..E....E...PL..T.....DY.....A.....A.....D.......IAA.K.W.....GLPMVSTGda..........ykaFNEKGV..K..-...-T.K...S.Y....GLVEITNLLQDPNWKGVQGEG.Q..HDLVIFMGCIYYMASQGLSTLKHFA..PHLKTLTICKFFHSNADA..SFPNMD.DDE.--WFRYLEKM-k..............................................................
D8PBI3_9BACT/44-198                  ....................................................epnedtvi-------.....-----------.---..-.--....-EEMARKMLTSPNATIFPGPLVL..W....A...WN..N.....HA.....V.....E.....K.......AQA.V.L.....EIAAQIPD...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFIGVHCHYANLTLKMIRAGT..NCCTMAICAEQGHEDAML..TIRDSD.TLK.LK---------ktaqifkkvreem..................................................
F6BF45_METIK/5-144                   .........................................................mid---RTTP.....YQPTAGTNLNH.ADV..V.SP....-TILIQMIKRSKNPILIVGCKLD..K....D...V-..E.....E-.....-.....-.....-.......ILS.K.L.....NMKKIHTP...............------..-..-...-K.E...M.N....LLDIMKYLAK----------G.E..HDLALFIGITYYYLAQALTHLKHFS..-SVITVTIDPYYHPNACY..SLPNME.KNE.--HVEVIKKL-v..............................................................
A0B5W4_METTP/5-177                   ..........................................................tt--KNPIP.....FEMAQIPGPEM.AKA..Y.PV....-KVIGAIIKKAKRPLLVVGAELF..D....D...PV..M.....FD.....K.....A.....I.......EIA.KaK.....NMTIAATAht..........ikgFIERGY..T..-...-T.N...V.Yq..iGLHPLTNYLRFKDWKGLDGQG.H..YDVVIFMGIFYKFANAMFSALKHFN..RDIKRVSIDRYYHVNADM..TFGNLA.FDS.AGYHEAIDEL-i..............................................................
A0A165Z8J4_9EURY/1-167               ..........................................................mn--ERLIP.....WQPTAIAGPKQ.PLL..V.TP....-ETAKHMIKKSKRPLFVVGPYAK..N....E...PL..L.....DF.....V.....S.....K.......IAE.K.W.....NLPIVTTAdt..........yktFSDVEI..D..-...-S.T...P.Y....GIVEIVNLLKDPQWQGVNGEG.Q..HDLVIFVGVIYYIASQGLSTLKHFA..PHLKTLTICKYFHFNADA..SFPNMN.DKE.--WHNYLDK--l..............................................................
ACDE_METTH/4-171                     ...........................................................l-NDRIIP.....WQPTVIAGPKQ.AML..V.TP....-ETATMMIKKARRPLMVVGPLAK..R....Q...EV..L.....EH.....T.....V.....K.......IIR.H.F.....DLPVVATAdt..........yraLSEAGI..E..-...-S.E...P.H....GIVEITNLLKDPSWEGIRGEG.Q..HDLVIFIGCIYYIASQGLSSLKHFA..PHIKTLTICKTFHSNADA..SFPNMD.DDE.--WFRYLEKMY...............................................................
A0A562S9H4_9DELT/24-185              ........................................................gvml----PDP.....--GQAIMEGES.VDR..D.TA....LRAAALKLIEARNPVFFPGPLIL..W....D...WK..P.....GV.....A.....E.....K.......ATA.L.K.....ELAEAVGA...............-KMIPM..P..D...YR.P...K.Y....PMINPAIEVNPNHPNLTIWHN.K..IDVCLFIGVHCHYANLALKIIRGGT..DCYTIAVCAEAGHEEAMI..SLRDAG.LCE.---LQR-----lrelv..........................................................
A0A0F7IDL1_9EURY/4-178               ...........................................................k-KEEKYPva.rrYQVADIQVSRD.ATP..V.KP....-SVVVNLVKKAKHPVLVTGGKLL..K....E...EK..L.....VE.....Y.....A.....V.......KFY.E.K.....GIPIIATGgs..........skpLIERGV..K..P...QS.I...V.F....PLHYVTQFMLDEEWQGFDGKG.N..YDVVLYLGFLPYYLSRMLSALKHFS..-KITTISLDEFYQPHAKF..SFTNLT.ANK.EMHYQMLEEVL...............................................................
A0A1D2W7Y7_9EURY/1-168               ..........................................................mn--ERVIP.....WQPTVIAGPKQ.ALL..V.TP....-ETAEMMLKKAKRPLMIMGPLIK..E....S...SA..L.....PF.....A.....V.....L.......IAE.K.R.....NIPIVSTGdm..........fktLNESDI..K..-...-S.K...P.Y....GVVEIVNLLKDPDWGGINGEG.Q..HDLVLFIGVIYYIGSQGLSTLKHFA..PHLKTLTLCKFFHSNADA..SFPNMK.DEE.--WIKYLEKL-a..............................................................
A0A133U9T6_9EURY/11-116              ...................eiiersnatvfktesagaeeinvetdarfglmeivdrlcng-------.....-----------.---..-.--....-----------------------..-....-...--..-.....--.....-.....-.....-.......---.-.-.....--------...............------..-..-...--.-...-.-....------------------MEE.E..YDFIVLAGVPYHIETRVLSGLRSYG..-VGTVITLNWRHQQYADF..SYRNMT.NLE.-DWKKELKEVL...............................................................
A0A1F2P2R6_9EURY/7-180               .........................................................spq---SSIP.....FDVGNIPGPES.GRL..V.TP....-ETIGRLIKSAKRPLLIVGAEIL..E....D...R-..M.....IE.....R.....A.....I.......AIG.K.K.....GVPIAATGpa..........irgFVEREY..D..-...-G.E...V.Yy..cQLHELTNCLLDPEWKGLDGKG.S..YDVVVFFGVTYYYASAMLSAIKNFAtnPLIRGVSIDRYYHPHARM..TFGNYGpKRE.EEYLRMIDKL-i..............................................................
A0A3M0BIC1_9AQUI/18-183              ........................................................egvl----NPP.....-QGKALLFDKV.VDK..E.TA....MREAAKAMLTRENPTIFVGPLVL..Y....A...WN..E.....DA.....E.....K.....K.......AKL.V.K.....EMAEVLNA...............-RIIPM..Y..D...YR.P...K.Y....PKVDPEVEINPNHPNLTIWQN.N..IKACIFIGVHDHYASVALKIIRCET..DCFTISLDTPSGHEDAMI..TIRSTD.VED.LEKFIEIAKE-v..............................................................
J9ZEC3_LEPFM/39-199                  ......................................................itlpdp-------.....--GQGHIEGRI.VSE..D.EA....IEEAARKLSAAKVPTFFPGPQVL..W....K...WN..E.....KS.....A.....K.....M.......AKV.I.K.....K-ASVEGG...............IKIIPM..S..D...YR.P...K.Y....PKIDPETEINPNHPNLTIWHN.K..IDVCLFVGVHCHQANLALKIIRGGT..SCYTLAFCSFAGHEDANL..SIRDTG.PEK.---FEKLTEF-l..............................................................
E3GYE4_METFV/2-157                   .........................................................yti-------.....--------RKN.AMR..L.KP....-ETFKSMLKRFDRPLLVAGPLVI..E....N...SV..L.....DL.....V.....I.....N.......IIK.R.W.....NLPVVATAnt..........ykfFAEKNV..E..-...-A.K...A.Y....GLVEIVNLLQDKQWKGLDGKG.Q..YNLVIFIGCNYNVLLQCLSSLKHFA..PHIKTITICKHYYPNAYA..SFPNMD.NRR.--WLKYLKKIL...............................................................
A0A166DE02_9EURY/1-168               ..........................................................mn--ERVIP.....WQPTVIAGPKQ.ALL..V.TP....-ETAKLMLQKAKRPLFVVGPYAK..D....E...PL..M.....SH.....V.....V.....D.......ISK.E.W.....NLPIVTTAdt..........ykkFNDNEI..E..-...-T.D...S.Y....GIVEITNLLKDPEWKGVKGEG.Q..HDLAIFVGCIYYIASQGLSTLKHFA..PHLKTLTICKYFHSNADA..SFPNMK.DKE.--WYAYLEKL-k..............................................................
C4FIQ3_9AQUI/19-183                  .........................................................gil---TPPP.....--GKALIFNEI.VDE..D.IA....MREAAKAMLTRQNPTIFPGPQVL..Y....A...WN..E.....EA.....K.....E.....K.......AKL.V.R.....KMAEVLGA...............-KIIPM..Y..D...YR.P...K.Y....PKINPSVEINPNHPNLTIWHN.K..IKACIFVGVHCHYANVALKIIRAET..DCFTIAMCSMAGHEDAMI..TLRDQH.AED.MERFIKIAEEV...............................................................
A0A2V3JNJ2_9EURY/10-166              ....................................................myttfgik-------.....----------S.ATP..L.KT....-GVAAKLISKAKRPLLIVGAGIL..E....D...E-..L.....LK.....R.....A.....L.......SMS.V.L.....GIPIAATGds..........lkgFVEAEV..D..-...--.A...S.Y...vNLHSIAQFMADPDWPGLDGCG.S..YDLAIFLGHKKYYVNQVLSGFKNFI..-PIKTMAIDRHYIQNANM..SFGNLS.VKD.--HLQALDEL-i..............................................................
T0XR13_9BACT/24-142                  ............................................gldlpvvgtgtvegrv-------.....-----------.LPE..A.QV....LEEAARKLAHAKVPTFFPGPMVL..W....Q...FT..P.....ES.....R.....Q.....V.......ADA.V.L.....EVAESNGI...............-RIIPM..P..D...YR.P...K.Y....PKIEPESEINPKHPNLTIWHN.K..IDVCLFVGVHCS-------------..------------------..------.---.-----------llqhc..........................................................
I0IRF5_LEPFC/39-203                  .....................................................gnilpep-------.....--GFGHIEGRI.VNE..D.QA....VEEAARMFVGAKVPTIFPGPLVL..W....G...WN..E.....KA.....I.....K.....T.......AEA.V.E.....RLSIAGG-...............INIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTIWHN.K..IDVCMFIGVHCHYANLSLKIIRGGT..ACYTMAFCAEAGHEDANL..SVRDMS.PTK.LDKVTE-----ivkkl..........................................................
A0A2U0RWS8_9ARCH/4-178               .......................................................msikv-----DP.....WQTAEVAGPKK.ANV..I.MK....AEVIAAMIKRAKRPILVIGYLST..K....A...DK..E.....TG.....K.....M.....L.......DYA.I.RmnkacGIPVVATAht..........ikeLVKLGF..T..-...-S.A...V.Q...mSAMDIGNRLKDPDWQGLDGKG.P..YDVALFMGWPYYMEYVILSGLKHFS..QNLKTISLNRYYNPNASW..SFPNLK.VEE.--WTQSFE---tii............................................................
A0A0D8IAM4_9CLOT/24-188              .........................................................gve-----LP.....EKGEALVEGTV.VFE..E.EA....MEKIAEKILAAKNPVFFPGPLIL..W....A...WK..E.....GV.....I.....E.....K.......AEA.V.K.....ELAETAGA...............-RIIPM..P..D...YR.P...K.Y....PMIDPEVEINPNHPNLTIWHN.K..IDLCVFVGVHCHYANLALKIIRGGT..DCYTVALCGEMGHEDAMI..SLRDVN.IST.I---KKLTEM-ikva...........................................................
D3DIA0_HYDTT/21-183                  ........................................................gvel----PPP.....--GKALLYGKI.VDE..E.TA....MREAAKAMLTRRNPTIFPGPLVL..W....G...WN..A.....SA.....M.....E.....K.......AKA.V.L.....ELAMEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.K..IEAAIFVGIHCHYANLSLRMIRAGT..NCFTIALCAEMGHEDAMV..SLRDQH.AEE.IRRF-------rdvl...........................................................
A0A2V2N613_9EURY/7-174               ......................................................wiraem-------.....------GGTSH.ASV..I.GK....PEVIVALLNRVKRPIFIIGHEIA..A....T...SP..D.....CEsltgfI.....S.....T.......VSR.V.R.....HIPVLGTSpa..........vkgLISHGI..S..-...IE.A...I.M....GGMEIADRLRDPEWKGFDNLG.Q..YDLVLFAAIPYSFCWTILSGLRNSA..PHLNTINLNRKYQPHATW..SFGNIA.VDP.--WK-------kqlqaaa........................................................
A0A1M6TGC0_9AQUI/552-726             ............................................ptpqedrtrtamqeev-------.....FKGEATIGDRA.VSY..K.EA....LEYIAKLIKESKRPTLVVGPLLL..W....D...FG.eE.....EL.....R.....Q.....K.......AQA.V.R.....ELLEKLDK...............VMVKIL..P..D...YR.P...K.L....KKYDPTVEMDPPNPYHTILHT.Q..NDLTLLVGVHCYRTDFVIRMLRKHT..PTTIVTLCGLYGHPEAHAstSFTDAE.K--.-----------irdltkll.......................................................
N0BI82_9EURY/2-173                   ...........................................................a-KAFEQP.....FDAANIPGPKM.ATL..L.EK....GKPVANMIKRAKRPLLIVGPDM-..T....D...A-..M.....FE.....R.....V.....L.......RFA.E.K.....GMTIVATGsa..........itrFVEAGY..K..G...NN.V...K.Y...aVLHELTQFLLDPEWKGLDGNG.N..YDLVLMLGTIYYHGSQMLAAIKNFA..PHIRALAIDRYYHPNAAM..SFGNLW.KKE.EDYLKLLDEIL...............................................................
A0A177QHS2_9BACT/43-195              ...................................................leenedkvi-------.....-----------.---..-.--....-EEMARKMLTSPNATIFPGPLVL..W....A...WN..E.....HA.....I.....E.....K.......AKA.V.L.....EIAAQIPD...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFVGVHCHYANLTLKMIRAGT..NCLTMAICAEQGHEDAML..TIRDSD.TVK.-----------lrktaqvfkrvr...................................................
A0A4C1WX79_EUMVA/108-223             ...................................................adhladllk-------.....-----------.---..-.--....-----------------------..-....-...--..-.....EV.....V.....T.....D.......SKL.I.K.....EIELKRTK...............LQEILL..R..Y...LQ.R...E.Y....VMRQNLGEINPE----SQQHQ.L..HDAALYLGVKVYELLKHPDVIRNPA..DITVLLMLQNFYKAAA--..------.---.-----------teikkynmedpvlskll..............................................
W9DTU2_METTI/5-167                   ..................................................tkntqiyatw-------.....-------GRNV.AKP..V.NP....-NVAGKLITKAKRPLMVVGSEIL..K....D...EK..L.....VE.....K.....T.....I.......AIA.R.K.....GVPVAATG...............HSITALvdK..D...IG.A...K.Y...iNVHSLGHFLGDKNWGGLDGQG.S..YDTILFIGHKKYYLNQVLAGIKNFT..-DLKTIAIERNFMQNATL..SFGNLK.PEV.--YLEALDEF-i..............................................................
A0A133UGI6_9EURY/15-110              .............................teatgtknvdveadaryglmeivdrlcnelg-------.....-----------.---..-.--....-----------------------..-....-...--..-.....--.....-.....-.....-.......---.-.-.....--------...............------..-..-...--.-...-.-....--------------------T.S..YKYIILAGIPYHIESRVLAGLRSYS..-VETVVTFNWRHQQYADI..SFNNLN.QKQ.--WKKSL----ktiakql........................................................
A0A1Q6DUX4_9EURY/4-111               eekvkkllsklkymyykteldgrevefeefleglsegesfkgvihtetevkennkirdgy-------.....-----------.---..-.--....-----------------------..-....-...--..-.....--.....-.....-.....-.......---.-.-.....--------...............------..-..-...--.-...-.-....---------------ILIDEG.E..IKLVIFMGKDIYYGSEALDMIKNP-..------------------..------.---.-----------dkinytrlkeskkeeil..............................................
A0A133VET1_9EURY/3-152               ........................................................getc-------.....-------GRKK.ASE..L.KP....-KALGKMLARAENVLFILASEVD..R....Y...--..P.....SD.....I.....L.....K.......EIV.E.K.....SNATVYKTea...........agTEKVDI..-..D...TD.A...R.Y....GLMEIVDRLCN------EMGE.E..YDYIVLAGVPYHIETRVLSGLRSYG..-MKKVVTLNWRHQQYADL..SFPNMP.DAE.-RWKKSLNEI-a..............................................................
O67252_AQUAE/19-183                  ..........................................................gv--LTPPP.....--GKALMFNEI.VDE..E.IA....MREAAKAMLTRDNPTIFPGPQVL..Y....A...WN..E.....EA.....K.....E.....K.......AKL.V.R.....KMAEVLGA...............-KIIPM..Y..D...YR.P...K.Y....PKIDPEKEINPNHPNLTIWHN.K..IKACIFIGVHCHYANVALKIIRAET..DCFTIAMCSMAGHEDAMI..TLRDQH.VED.LEKFIKIAEEV...............................................................
F2KT92_ARCVS/7-159                   ................................................lprgykqselqc-------.....---------EK.AAC..V.TP....-KEAADIISY-SRPVLITGGMLL..E....N...SR..L.....VE.....Y.....A.....V.......KL-.S.E.....HMPVIATGas..........skvLVSRGV..K..P...LS.C...V.F....TMHHIAQFILD---GGWDVTK.R..FDTAVFLGFRPYYLSRVLSTLKHFS..-GMTTISLDELYQPNAHY..SLTTL-.---.-----------aivide.........................................................
A0A133UUD4_9EURY/1-157               ........................................................mpdp-------.....YMYGETSGRKS.ATQ..L.RA....-KALGNMLSRAENVLFILASEVG..R....Y...P-..-.....ED.....T.....L.....K.......KII.E.K.....TGATVYKT...............-ESAGS..N..D...LD.I...E.A...dERLALMEIV-D---RLCDGMGeE..YDYIILAGVPYHIETRVLSSLRSYG..-VDTVVTLNWRHQQYADF..SFKNTP.DKE.-KWE-------kelkvil........................................................
A0A330L3J0_9BACT/22-194              ........................................................girl------P.....NPGEAHINGVI.VSE..E.KA....YEEAARQFLMAKVPTLFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......ATA.I.R.....HLYNTLKEcvq........pgqkPMLIPM..P..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.K..IDCCMFIGVHCHQANLSLKIIRGGT..SCYTIAMCAQAGHEDAML..SFRDAS.VEK.I----------mtladwvrkl.....................................................
A0A177Q8F3_9BACT/22-180              .........................................................gvv-----LP.....SKGEGLVLGKI.VPE..Q.QA....IDEAARRLLNAKNPTIFPGPLVL..W....A...WN..A.....QA.....K.....Q.....E.......AKV.V.K.....ALAKAITA...............-KLIPM..P..D...YR.P...K.Y....PKIFPEKEINPNHPNLTIWQN.K..IDVCLFVGVHCHQSNIALKIIRGGT..NCFTIALCTFNGDDEAHI..TIRDLT.VA-.-----------tiqriv.........................................................
A0A0K2G932_NITMO/43-196              .....................................................gllepne-------.....-----------.---..E.KV....IEEMARKMLTSPNATIFPGPLVL..W....A...WN..E.....HA.....V.....E.....K.......AKA.T.L.....EIAAQVPD...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFIGVHCHYANLTLKMIRAGT..NCCTMAICAEQGHEDAML..TIRDSD.TAK.L----------krvaqifkrv.....................................................
B1I5X8_DESAP/23-188                  .........................................................mgv----ELP.....QRGEALVEGRV.VPE..E.DA....FRVIAEKLLTARNPVFFPGPKIL..W....A...WK..D.....GA.....V.....E.....K.......ARA.V.L.....KLMEAVGA...............-RAIPM..P..D...YR.P...K.Y....PMINPAVEINPNHPNLTIWHN.R..IDVGVFVGVHCHYANLALKIIRGGT..DCYTIALCGEVGHEDAMI..TLRDVD.AGK.LERL---TE--varal..........................................................
A0A497XQP2_9AQUI/18-183              ........................................................edil---TPPP.....--GKALLFNEI.VDE..E.IA....MREAAKAMLTRENPTIFPGPQVL..Y....A...WN..E.....EA.....K.....E.....K.......ARL.V.R.....KIAETLGA...............-KIIPM..Y..D...YR.P...K.Y....PKIDPEKEINPNHPNLTIWHN.N..IKACIFIGVHCHYANVALKIIRAET..DCFTIAMCGNAGHEDAMI..TLRDQH.TEE.LEKFIRVAEE-v..............................................................
L0HDF9_METFS/1-174                   ......................................................mpmtda-------.....WQTAEIAGPKK.ASL..I.LK....PDIADALISRAKRPIMIVGHGIV..E....Y...EV..NgkpmiEC.....L.....I.....A.......LAR.K.A.....VIPVVVSAst..........nreF---LS..R..E...FE.P...A.Av..mSAVEISSRLTDPEWKGLDGKE.P..YDLAIFVGLPYSMEWTILSGLKHFA..PNVKTMTFDCVYQPNASW..SFPNST.IKD.--WA-------anlkgiv........................................................
D8PBX5_9BACT/22-117                  ........................................................giyl------P.....NPGEAHINGVI.VPE..E.KA....YEEAARQFLMAQVPTIFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......AAA.V.R.....KLYEILKEcvq........pgqkPMLIPM..P..D...YR.P...K.Y....PKINPE---------------.-..-------------------------..------------------..------.---.-----------ve.............................................................
A0A2C6MBJ6_9FIRM/24-186              ........................................................gvml------P.....EKGESLVEGRV.VPE..E.EA....LQKIAEKLLAAKNPTFFPGPLIL..W....D...WK..A.....GV.....A.....E.....K.......AAA.I.K.....ELAETVGA...............-KIIPM..P..D...YR.P...K.Y....PMINPAVEINPNHPNLTIWHN.K..IDVCIFVGVHCHYANVALKIIRGGT..DCFTIALCGEAGHEDAMI..TLRDVN.LAK.---IKRLN---evik...........................................................
D3SNX7_THEAH/561-726                 .................................................tavqeevflge-------.....----ATIEDRI.VSS..S.EA....LATLADWIKRAERPTLVVGPLLV..W....D...WG..E.....EE....lR.....Q.....K.......AEA.L.R.....TLIEKIPH...............LKVKVL..P..D...YR.P...K.L....GKYDPSVEMDPPNPHQCVLHD.R..NDLTLLVGVHCYRTDFVIRLLRKHT..PTRVVTLCGLYGHPTAHL..SVSFTD.AEK.LYYLSR-----ll.............................................................
A8UTN3_9AQUI/557-728                 ..............................................edrtrlpivkekdk-------.....--NVGFINGEK.TEY..D.RA....LDLAVDMLLKAERPTIIVGPLVL..W....S...WN..E.....EA.....R.....K.....K.......AEL.V.R.....KLKDLFPY...............LNVHIL..P..D...YR.P...K.N....KEFDPAREIDPPNPHISILHG.K..HDLTLMLGVHCYRTDFVIRLLRKHT..DTKIVTLCNLYGHPEADV..SLSGMN.PEK.LERF-------vkraqk.........................................................
G7WQP4_METH6/5-176                   .........................................................ttk---NAVP.....FEMAQIPGPEM.AKA..Y.NT....-AVIGAIIKKAKRPLLVVGAELF..E....D...PV..M.....FD.....K.....A.....I.......AIG.K.T.....GVPIAATAhs..........ikgFVERGY..T..E...NV.T...M.I....GLHPLTNYLRFKDWQGLDGKG.Q..YDVVIFTGIFYKFASAMFSTLKNFN..RDIKRVSIDRYYHVNADM..TFGNLA.FDP.EKYHEAIDEV-i..............................................................
A0A4Q3E4U7_9RICK/1-38                ...........................................................m-------.....-----------.---..-.--....-----------------------..-....-...--..-.....--.....-.....-.....-.......---.-.-.....--------...............------..-..-...--.-...-.-....---------------------.-..---AVFIGRHYYIIAQKINKLKHFK..YSLIVISII---------..------.---.-----------nncysq.........................................................
O67557_AQUAE/619-788                 ...........................................................e-DMSRLPivretSTEIGFINGQK.VSF..E.EA....LQVAVELLSKAKRPTLIVGPLVL..W....A...WN..E.....EA.....K.....K.....K.......GEI.I.K.....RLKEKYPN...............LNIHLL..P..D...YK.P...K.N....KKVDFSREVDPPNPHLSVLYG.E..HDLTLMIGVHCYRTDFTIRMLKKYT..DTKIVTLCTLYGHPDADV..SLAGVN.SKK.---LEMFYEM-a..............................................................
B4U665_HYDS0/21-186                  .......................................................gvqia-----PP.....--GKALLYGEW.VDE..E.TA....MREAALAMLTRKNPTIFPGPLVL..W....G...YN..A.....SA.....I.....E.....K.......AQA.V.L.....ELAKEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.R..IEACIFVGVHCHYANLSLRMIRAGT..NCFTIALCAEMGHEDAMV..SIRDTH.AEK.LLEF-------rdvvvkl........................................................
M1Z137_NITG3/23-184                  ....................................................qpekgsrk-------.....----QLLEGEP.VDE..E.KV....YETAAVKLLTRRNPTLFPGPQII..W....G...WN..E.....EA.....R.....H.....K.......AEL.I.L.....NFVKEVPG...............MNIIPM..P..D...YR.P...I.Y....PKIDPEAVINPCHPNLTVLHN.K..IHVCILIGVHCHFANITLKMIRANT..PCYTQAWCAYDGHEDALL..SIRDTD.SEV.--ILK------mtetv..........................................................
I2KA06_9PROT/19-183                  ........................................................gvit-----PP.....-EGKALLLEDV.VDE..E.TA....MREVARVMLTSENATIFPGPQVL..Y....G...WN..E.....EA.....K.....K.....K.......ATL.I.K.....EMSEVLNA...............-KMIPM..Y..D...YR.P...K.Y....PKIDAEVEINPNHPNLTIWHN.N..IKAAIFIGVHCHYANVALKIVRAET..DCYTIAICGLSGHEDAMA..TLRDQH.SHE.LEKFIKIAKE-v..............................................................
F0T9G7_METLA/1-168                   ..........................................................mn--ERVIP.....WQPTVIAGPKQ.ALL..V.TP....-ETAKMMMKKAKRPLLVIGPLAK..E....E...PL..L.....TH.....S.....I.....E.......IAE.K.W.....DLPVVTTAdt..........fkiFSERNV..E..-...-T.K...S.Y....GTVEILNLLKDPEWKGIRGEG.Q..HDLVIFVGGIYYMASQGLSTLKHFA..PHLKTLTLCKYFHSNADA..SFPNMN.DEE.--WSKYLEKM-k..............................................................
A7I829_METB6/1-175                   ........................................................mssa-----DP.....WQTAEVGGPKK.ATV..I.TK....PAMAKAVIGRARSPVLLLGNQSA..S....A...EI..G.....DR.....K.....LvdyllV.......LAR.A.Y.....RIPVIATG..............nV-NRAL..V..E...RG.Y...M.NalilPAVVAGQRIADPVWEGPGGKG.P..CDLAIIAGLPYPMAWTLLSGLKHFA..PHTRTITLDNKYQPNATW..SFANLS.EKD.--WQENLE---aiie...........................................................
F2KTA2_ARCVS/6-176                   ...........................................................k-KVRKPPe..klFNTADIQASRS.AKL..I.KP....-DVLAKMVGRAKNPVLVTGGKLL..E....D...EK..L.....VE.....Y.....A.....V.......KLY.E.N.....GVAIIATGas..........srpLIERGV..E..P...QA.C...V.F....TLHHVTQFLLDESWSGFKGE-.P..YDLVLFLGFEPYYLSRMLSALKHFS..-KLTTVSIDAFYQPHARF..SFPNTL.DLH.-----------heileefvt......................................................
A0A2V3JP39_9EURY/3-163               .....................................................rayqcan-------.....-----VPGPHL.GKV..A.TS....-ASVAAAIKRAERPVLIVGSELR..H...lD...W-..-.....--.....A.....L.....N.......LAK.E.M.....DIPIVATAqv..........agvMREKGV..R..P...DR.E...M.-....GVIEITNLLKSPEWGGVRAEG.Q..HDLAIFADVLYYMEAQMLSALKHFA..PHIKTISLTRGHQPNANQ..SLPNLS.EKK.--LAEFLAE--iv.............................................................
A0A2V3JRY2_9EURY/14-114              ................................................rkgsggrkvats-------.....-----------.---..-.--....-ASVAAAIKRAERPILIVGSELR..H...lD...WV..L.....--.....-.....-.....D.......LAK.D.L.....DIPVVATAqv..........agvMREKGV..R..P...DR.E...M.-....GVIEITNLLKSPEWGGVRGEG.W..ADEK---------------------..------------------..------.---.-----------tfiq...........................................................
A0A0S4KN86_9BACT/52-203              ...................................................lepneevvi-------.....-----------.---..-.--....-EEMARKMLTSQNPTIFPGPLIL..W....A...WN..D.....HA.....V.....E.....K.......AKA.T.L.....EIAAQIPE...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFVGVHCHYANLTLKMIRAGT..NCCTMAICAEQGHEDAML..TIRDAD.TAK.L----------rrvaqifkrv.....................................................
I0IS74_LEPFC/23-185                  .....................................................vilpdpg-------.....---ESLVQGSI.FNE..E.EA....LIIAADKILAAKNPTLFPGPLVI..W....N...WS..K.....ES.....Q.....E.....M.......AKA.V.R.....KLAEA-GN...............MNIIPM..T..D...YR.P...K.Y....PKINPESEINPNHPNITIWHN.A..IDVCLFVGVHCHYSNIALKIIRGGT..DCFTIALCSFSGDDEAHL..TVRDVS.PEK.VDRLSQI----lre............................................................
D3DJP9_HYDTT/551-727                 ..........................................aaptpeedmtrtsmqkev-------.....FKGEATIGEEA.VSF..K.EA....VKLLVKWIKESKNPTLVIGPLLF..W....D...WK..E....kEL.....L.....E.....K.......GEV.L.R.....RLIEKVGR...............FNVKVM..P..D...YR.P...K.L....KKYDPTVEMDPPNPHHAVLYG.K..HDLTLLVGVHCYRTDFVIRLLKKHT..DTKVVALCGLYGHPTADLstSFTDAQ.KLE.-EILKML----...............................................................
A0A133V8E3_9EURY/3-154               .........................................................get-------.....------SGSKS.AID..L.KP....-KVAEKLLAKAKSVLFILGSDLN..E....Y...P-..P.....KT.....L.....K.....K.......IIE.K.A.....NSTVVETGs............akASDIGI..E..-...AD.S...R.Y....GIVEVVDLLCSDD----GWRG.R..HDYVVFVGVPYHIESRMLSGLRLCN..-VGRTITLNRRHQQYADF..SFPNIL.RPK.-FW--------ekslkeia.......................................................
B1I1E9_DESAP/5-180                   .......................................................eflfv------P....yYTVNTLTGTKA.AQV..V.SD....PVEAAEIIDRARNPLYILGPEAI..T....AavgEK..L.....LL.....E.....Y.....V.......LEI.V.Ka...sSILTCATA..............hVKKKML..E..F...GK.KpdcV.Y....DIIEIIHFLKMPDWQGVRGRG.P..HDLVLFTGIRCDLAERGLATLKHFA..PHLKTFAVCRRGHPNADY..TTPVIP.RME.-KWRDYLEEI-i..............................................................
A0A177QA95_9BACT/16-185              ........................................................girl------P.....NPGEAHINGVI.VPE..E.KA....YEEAAKQFLMAKVPTLFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......ATA.I.R.....HLYNTLKEcvq........pgqtPMLIPM..P..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.K..IDCCMFIGVHCHQANLSLKIIRGGT..SCYTIAMCAQAGHEDAML..SFRDAS.VEK.-----------imtladav.......................................................
A0A1V6N5A4_9EURY/1-169               ..........................................................mn--DRVIP.....WQPTVIAGPKQ.ALL..A.TP....-ETAKLMLRKSKRPLFVVGPYAK..N....E...PL..M.....GL.....I.....K.....D.......IAE.A.W.....DLPIVTTAdt..........fksFNENGI..E..-...-S.N...Y.Y....GIVEITNLLKDPEWKGIRGEG.P..HDLVMFVGCIYYIASQGLSTLKHFA..PHLKTLTICKYFHSNADA..SFPNMK.DEE.--WENYLEKM-se.............................................................
ACDE_METBU/8-168                     ....................................................tqihctyg-------.....--------CKS.SKA..V.QP....-DVAGKMISKAKRPLFIVGSQIL..K....D...EE..L.....LK.....R.....S.....I.......EIA.K.K....aDLPVAATGhs..........msgLVDQGV..N..-...--.A...K.Y...iNVHALATYLCDPNWTGLDGKG.Q..YDTIIVLGHFKYYIDQVLSGLKSFS..-KLKSIAIEREYIQNATM..SFGNIT.PA-.-----------vhiealdeli.....................................................
D7E801_METEZ/8-168                   .....................................................trvyttw-------.....-------GTKN.AKP..V.QP....-KVAAKTISKAKRPLMIVGAELL..K....N...KE..V.....LD.....R.....A.....V.......TIAkT.A.....GIPVAATGhs..........ikeLVDKGV..-..-...-N.A...K.Y...iNIHSLGLYLCDPNWGGLDGNG.C..YDMAIILGHKKYYINQVLSGLKNFT..-NLKTISIDKHYLQNATM..SFGNLN.DEK.--HIEALDEL-i..............................................................
U6EBR4_9EURY/2-169                   ...........................................................a-NDRVTP.....WQPTVIAGPKQ.ALL..V.TP....-ETAELMIKKAKRPLLVLGPLVK..E....E...PV..L.....SL.....A.....T.....G.......IAK.K.W.....DLPVVTTAda..........ykpFKEKGL..E..-...-P.T...A.Y....GVVEIVNLLKDPEWSGIKGEG.Q..HDLVIFLGCIYYIGSQGLSTLKHFA..PHLKTLTLCKFFHSNADA..SFPNMK.HEE.--WLSYLEKM-g..............................................................
C4FIH7_9AQUI/19-181                  ........................................................gvel----PPP.....--GKSLLYGKI.VDE..E.MA....MREAAKAMLTRKNPTIFPGPLVL..W....G...WN..A.....GA.....M.....E.....K.......AKA.V.L.....ELAMEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.K..IEACIFVGVHCHYANLSLRMIRAGT..NCFTIAMCAEMGHEDAMV..SLRDVH.ADE.IRRFK------dvl............................................................
D3RWN9_FERPA/4-178                   ...........................................................k-KEDKYPva.rrYQIADVQVSRE.ATA..V.KP....-QVVVNLIKKAKHPVLITGGQLL..K....D...EK..L.....VE.....I.....A.....V.......KFY.E.K.....GIPIIATGgs..........skpLIEKGV..N..P...QS.V...V.F....TLHQVTQFLLDEEWKGFDGKG.N..YDLVLFMGFLPYYLSRMLSALKHFS..-KITTVALEEFYQPHAKF..SFTNLT.ANK.DMYYSMLEEIV...............................................................
ACDE2_METAC/9-167                    ..................................................klftsygvtt-------.....-----------.SKT..T.TP....-EIAAKLISKAKRPLLVVGTKVL..D....P...EL..L.....DR.....A.....V.....K.......IAQ.K.A.....NIPIAATGs.............sMPGFVG..K..D...VD.A...K.Y...iNLHQLGFYVTDPNWPGLDGNG.T..YDTLIVLGHIKYYINQVLSGTKNFS..-TVKAIAIERNYIQNATM..SFGNLS.KAD.--HYAALDEL-i..............................................................
A0A0E3NUM5_9EURY/8-167               ................................................tklftsygvtts-------.....-----------.-KA..I.NP....-DMAAKMIKKAKRPLLVVGSGIL..K....P...EL..L.....DR.....A.....V.....K.......IAQ.K.A.....NLPIAATG...............HSHVGFldK..D...VD.A...K.Y...iNVHQLGFYLTDPNWPGIDGNG.N..YDMVIVLEFKKYYINQVLSGTKNFS..-NLKAISIGRDYIQNATM..SFGNIS.RED.--HYVALDEL-i..............................................................
D3SQJ0_THEAH/19-183                  .........................................................gvl---NPPP.....--GKALMFNEI.VDE..E.IA....MREAAKAMLTLPNATIFPGPQVL..Y....A...WN..E.....EA.....K.....Q.....K.......AKL.V.K.....KMAEVLNA...............-KIIPM..Y..D...YR.P...K.Y....PKINPEIEINPNHPNLTIWHN.K..IKACIFVGVHCHYANVALKIIRAET..DCFTIAMCGMAGHEDAMI..TLRDQH.VEE.MEKFIRIAQE-v..............................................................
B4U695_HYDS0/494-667                 ............................................ptpeedrtrsamqidv-------.....FKGEATIKDSV.VSY..K.EA....FKELASLIKSSKNPTVVVGPLLF..W....D...FN..E.....KD....lQ.....E.....K.......AYI.T.R.....LLIEKINA...............-NVKIL..P..D...YR.P...K.L....KNYDPNVEMDPPNPHEAILHG.N..HDITILIGTHCYRTDFVIRLLKKHT..PTKVVALCGLYGHPEADLstSFTDAN.KLK.-ELLDML----...............................................................
F7XMA1_METZD/13-174                  ..................................................tkntaisttw-------.....-------GTKI.AKP..V.QP....-KVAGKLISKAKRPLLVVGGDVL..-....D...ED..L.....LK.....R.....A.....I.......QIG.K.K.....GIPIAATG...............HSMKGFvdA..D...VD.A...K.Y...vNIHSLGLYLGDPQWHGLDGNG.Q..YDLIIVLAHKKYYINQVLSGIRNFT..-DLKTLSIDRNYIQNADM..SFGKLD.KET.--HLKALDEL-i..............................................................
C6HUY7_9BACT/22-186                  .....................................................gvappep-------.....--GFALIEGVA.ASE..E.EA....IETAARKLATAKVPTFFPGPMVL..W....E...WS..-.....-E.....K.....T.....R.......KVA.D.A.....VLRCAETN..............nIKIIPM..A..D...YR.P...K.Y....PKIEPELEINPNHPNLTIWHN.K..IDACLFVGVHCHYANLSLKIIRGGT..SCYTMAFCSYAGHEDANL..TIRDNS.AEK.FDRL-------saaikkm........................................................
ACDE_METJA/4-144                     ..........................................................rf--IAYIP.....---TAGSNVAH.AEI..T.SP....-TLVKMMIRRAKKPILILGENLE..E....N...E-..K.....EL.....I.....S.....K.......LIE.K.F.....NLKTIKTP...............------..-..-...-E.E...M.N....LMAIMKYLASS----------.D..YDLALFTGITYYYLAQAATHLKQFS..-NVVTISIDKYYQPNTLY..SFPNLS.KEE.--YLDYLRKLL...............................................................
A0A0K2G8I3_NITMO/22-195              ........................................................girl------P.....NPGEAHINGVI.VPE..E.KA....YEEAAKQFLMASVPTIFPGPLVL..W....A...WN..E.....KA.....A.....K.....K.......ATA.V.R.....HLYNTLKEcvq........pgqkPMLIPM..P..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.K..IDCCMFIGVHCHQANLSLKIIRGGT..SCYTIAMCAQAGHEDAML..SFRDAS.VEK.I----------mtladwvkklk....................................................
A0A497XSR2_9AQUI/23-185              ........................................................gvel----PPP.....--GKALLYGEI.VDE..E.TA....MREAAKAMLTRKNPTIFPGPLVL..W....G...WN..A.....GA.....M.....E.....K.......AKA.V.L.....ELAMEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.K..IEACIFVGVHCHYANLSLRMIRAGT..NCFTIALCAEMGHEDAMV..SLRDVH.AEE.IRRFK------dvl............................................................
A0A1M6S155_9AQUI/19-183              .........................................................gvl---NPPP.....--GKALMFNQI.VDE..E.IA....MREAAKAMLTRQNPTIFPGPQVL..Y....A...WN..E.....EA.....K.....E.....K.......AKL.V.K.....KMAEVLNA...............-RIIPM..Y..D...YR.P...K.Y....PKINPAVEINPNHPNLTIWHN.K..IKACIFVGVHCHYANVALKIIRAET..DCFTIAMCGMAGHEDAMI..TLRDQH.IEE.MEKFIKIAEEV...............................................................
Q6LYK7_METMP/3-170                   ..........................................................gd---RTTP.....WQPTVIAGPKH.GML..V.TP....-AIAKMMLKKAKNPLFVIGPLIK..D....D...EE..L.....IS.....L.....C.....K.......SIV.EaW.....NLPVVATGni..........yksLTEKGI..K..-...-S.K...R.Y....GTIEIVNLLKDSEWKGINGEG.S..YDLVLFIGVTYYLASQGLSSLKHFA..PHLKTVTLCKYFHSNADA..SFPNMS.DSE.--WTNYLEKM-s..............................................................
A0A133UIV2_9EURY/78-173              ............................kteatgtknvdveadaryglmeivdrlcnelg-------.....-----------.---..-.--....-----------------------..-....-...--..-.....--.....-.....-.....-.......---.-.-.....--------...............------..-..-...--.-...-.-....--------------------T.S..YKYIILAGIPYHIESRVLAGLRSYG..-VETVVTFNWRHQQYADI..SFNNLN.QKQ.--WKKSL----ktiakq.........................................................
A0A330L2K1_9BACT/44-198              ....................................................epnedkvi-------.....-----------.---..-.--....-EEMARKMLTSPNATLFPGPMVL..W....A...WN..E.....HA.....I.....E.....K.......AKA.T.L.....EIAAQIPN...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFIGVHCHYANLTLKMIRAGT..NCCTMAICAEQGHEDAML..TIRDSD.VLK.LKK--------taqifkkireem...................................................
D5EBX1_METMS/8-167                   ......................................................lkvytt-------.....------YGPKT.AKG..T.KP....-SIVAKMIEKAKRPLFVVGSEVL..E....E...E-..L.....LA.....R.....A.....K.......AIA.K.K.....GIPVAATG...............HSIKGF..I..DedgVD.A...K.Y...iNIHFLGTFLCDPKWAGLDDNG.C..YDLIILLGHKKYYINQVLSGLKNFS..-DLKTINIGRHYTQNATL..SFGNIT.PEV.--HLEALDEL-i..............................................................
A0A0S4L8E4_9BACT/43-197              ...................................................lepneevvi-------.....-----------.---..-.--....-EEMARKMLTSPNATLFPGPLLL..W....A...WN..D.....HA.....V.....E.....K.......AKA.T.L.....EIAAQIPE...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFIGVHCHYANLTLKMIRAGT..NCCTMAICAEQGHEDAML..TIRDSD.T--.-----------lkikrvaqifkriree...............................................
B4U6S5_HYDS0/19-183                  .........................................................gvl---TPPP.....--GKGLLYNEI.VDE..E.VA....MREAAKEMLTRENPTIFVGPLVI..Y....A...WN..E.....EA.....K.....E.....M.......AKL.V.R.....EMAEVLNA...............-KIIPM..P..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.N..IKACIFIGVHCHFANIALKIIRAET..DCLTIAMCAKMGHEDAMI..TVRDQH.PED.VRKFIEIAK--qv.............................................................
C6HUZ5_9BACT/23-186                  .....................................................islpdpg-------.....---QGHIEGAI.VPQ..E.QA....IEESARILSRAKVPTFFPGPLVL..W....K...WN..E.....KS.....A.....K.....M.......AAA.I.K.....N-AAVEGG...............IKIIPM..S..D...YR.P...K.Y....PKIDPETEINPNHPNLTIWHN.K..IDACLFVGVHCHQANLALKIIRGGT..DCYTMAFCSMSGHEDANL..SVRDTS.PET.---FLKL----tealkkm........................................................
A0A133UCH0_9EURY/11-116              ...................eiiersnatvfktesagaeeinvetdarfglmeivdrlcng-------.....-----------.---..-.--....-----------------------..-....-...--..-.....--.....-.....-.....-.......---.-.-.....--------...............------..-..-...--.-...-.-....------------------MEE.E..YDFIVLAGVPYHIETRVLSGLRSYG..-VGTVITLNWRHQQYADF..SYRNMT.NLE.-DWKKELKEVL...............................................................
A8V491_9AQUI/19-183                  ........................................................gvln-----PP.....-YGKALLFDEV.VDK..E.VA....MREAAKAMLTRENATIFPGPLVL..Y....A...WN..E.....EA.....T.....K.....K.......AKL.V.K.....EMAEVLNA...............-RIIPM..Y..D...YR.P...K.Y....PAVNPEVEINPNHPNLTIWHN.N..IKACIFIGVHDHYAEVALKIIRAET..DCLTISMDTYSGHEDAMI..TIRSAE.IED.LERFIEIAKE-v..............................................................
A0A497XN64_9AQUI/557-729             ...............................................edrtrlpivkekd-------.....-KNVGFINGEK.VRY..E.EA....FREAVKLLMKAERPTIIVGPLVL..W....R...WS..E.....ET.....E.....R.....K.......AEL.V.K.....KLKELFPN...............LNVHVL..P..D...YR.P...K.N....KNFDPSREIDPPNPHISILHG.N..HDLTLMIGVHCYRTDFVIRLLKKHT..DTKIVTLCNLYGHPDADV..SLSGIN.AEK.LEEF-------vnypsml........................................................
A0A0S4LAA9_9BACT/43-192              ...................................................lepneevvi-------.....-----------.---..-.--....-EEMARKMLTSPNATIFPGPLLL..W....A...WN..D.....HA.....V.....E.....K.......AKA.T.L.....EIAAQIPE...............VMIIPM..P..D...YR.P...K.Y....PKIDPEEVINPNHPNLTIWGN.K..IEACIFIGVHCHYANLTLKMIRAGT..NCCTMAICAEQGHEDAML..TIRDSD.---.-----------tlkikrvaqifk...................................................
D3SQ60_THEAH/22-184                  ........................................................gvel----PPP.....--GKALLYGEI.VDE..E.VA....MREAAKALLTRRNPTIFPGPLVL..W....G...WN..A.....SA.....M.....E.....K.......AKA.V.L.....ELAMEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.K..IEVAIFVGVHCHYANLSLRMIRAGT..NCFTIALCAEMGHEDAMV..SLRDVH.AEE.IRRFK------nvv............................................................
A0A062VAK5_9EURY/10-175              .........................................................ttr---QAVP.....FDTGNIPGPKM.AKA..V.MP....-SVAGKMLAKAKRPLLIVGSEVH..D....R...D-..V.....LE.....R.....A.....V.......AIG.Q.T.....GVQIAAVGna..........ytsLGDKGL..D..-...-V.H...Y.E....NMHALASYLCDPGWPGFDGKG.G..YDLVAFFGITYYYASQAISAIKNFS..-GIKVISMDRYYHPNADM..SFGNLK.NDV.--FIAALDEI-i..............................................................
A0A0J6YXM9_9BACT/23-185              ...................................................qpekgsgyq-------.....-----LVEGEH.VPE..D.KA....IETLATKLLTLRNPTLFPGPLIV..W....G...WN..K.....EA.....E.....H.....K.......AEL.S.L.....KLAEEVPG...............MNIIPM..P..D...YR.P...I.Y....PKIDPEAVINPCHPNLTIQHN.K..IKVCTFIGVHCHFANITLKMIRANT..NCYTMALCQYDGHEDALL..SIRDLD.SAK.LEK--------iidtvk.........................................................
A0A133UV11_9EURY/1-157               ........................................................mpdp-------.....YMYGETSGRKS.ATQ..L.RA....-KALGNMLSRAENVLFILASEVG..R....Y...P-..-.....ED.....T.....L.....K.......KII.E.K.....TGATVYKT...............-ESAGS..N..D...LD.I...E.A...dERLALMEIV-D---RLCDGMGeE..YDYIILAGVPYHIETRVLSSLRSYG..-VDTVVTLNWRHQQYADF..SFKNTP.DKE.-KWE-------kelkvil........................................................
F8ADR8_THEID/370-536                 .........................................................sda---YKLP.....EKDKALVEGEM.VSV..D.EA....LEKIAEKLLAAKYPVFFPGPTVI..W....K...TE..E.....RA.....K.....K.....A.......TAI.I.R.....KIVEEVGA...............-NIIPM..P..K...YW.K...P.P....VENPLVEEEARRFWTDNIWFN.R..IDVCVFVGVPCPYADVGLKILREET..DCYTIALCAHAGHKDAII..TLRDVT.PEV.LEKL-------yqavrei........................................................
R5KHL0_9BACT/182-256                 ..............................................ithqrvirsvsssl-------.....-----------.-DI..E.VF....RRFVSHMLSTAKRPMLLVGQICE..R....M...D-..E.....VE.....K.....A.....L.......KII.E.R.....SIAVLAEP...............LS----..-..-...--.-...-.-....---------------------.-..-------------------------..------------------..------.---.-----------sggqrlfdl......................................................
A8UW23_9AQUI/23-185                  ........................................................gvel------P.....EPGKALLYGEI.VDE..E.TA....MREAAKAMLTKRNPTIFPGPLVL..W....G...WN..A.....GA.....M.....E.....K.......AKA.V.L.....ELAMEIPN...............CRIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTILHN.K..IEACIFVGVHCHYANLSLRMIRAGT..NCFTIALCAEMGHEDAMV..SLRDVH.AEE.IRKFK------dvl............................................................
M1Z2F6_NITG3/23-185                  ......................................................ivlpdp-------.....--GQAHIEGRL.VDE..D.EA....VEYAARKILGAKVPTIFPGPLVL..W....K...WN..E.....KA.....A.....K.....K.......AKA.L.R.....RLADTAPM...............-RLIPM..A..D...YR.P...K.Y....PKIDPEIEINPNHPNLTIWHN.R..IDVCIFVGVHCHQANLALKIIRGGT..DCYTIAYCAQAGHEDACL..SLRDIG.VDT.I----------nnltdtier......................................................
J9ZG37_LEPFM/21-186                  ........................................................agni-----LP.....EEGQGHFEGQI.VSE..E.QA....IEESARKFASAKVPTIFPGPLVL..W....G...WN..E.....KA.....L.....R.....T.......AEA.V.E.....RLSVA-GG...............INIIPM..P..D...YR.P...K.Y....PKIDPEAEINPNHPNLTIWHN.K..IDVCMFIGVHCHYANLSLKIIRGGT..SCFTMAFCAHAGHEDANL..TVRDMS.PEK.VDKVTAI----lkkl...........................................................
A0A0J6YUB3_9BACT/23-186              ......................................................ivlpdp-------.....--GEAHIEGKI.VPE..E.EA....MECAARKFLEARVPTIFPGPLVL..W....K...WN..E.....KA.....A.....K.....K.......AKA.L.R.....KLANAIPA...............-RLIPM..A..D...YR.P...K.Y....PKINPEVEINPNHPNLTIWHN.K..IDVCMFVGVHCHQANLALKIIRGGT..GCYTIAMCAQAGHEDACL..SFRDAT.AEK.IDKLT------etierl.........................................................
#=GC SS_cons                         ...........................................................X-XXXXXX.....XXXXXXXXXX-.-EE..E.--....SHHHHHHHHHSSSEEEEE-S---..-....H...H-..H.....HH.....H.....H.....H.......HHH.T.S.....SSEEEEETTH..........HHHHHHTT-..G..-...-G.G...S.EE..E-HHHHHHHHHSTT--TTTSS-.-..-SEEEEES--HHHHHHHHHHHHHH-..TT-EEEE-SSS--TTSSE..EE---G.GGH.HHHHHHHHHHH...............................................................
#=GC seq_cons                        .........................................................hhh................th..sch.sp.....ps.....ctsAchlhpA+pPhlhsGPhll..h....s....p........ps.....h.....p.....c.......stt.h.t.....plshshsu...............hthhsh.....D...hc.s...+.Y....shlp.pt.lsssc.shhhhcs.p..hDhslFlGlchahushsLphl+sho..sshphshhsphhHpsAth..Shtshs.scc...hh.......h..............................................................
//
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