GenomeNet

Database: Pfam
Entry: CoV_NSP2_N
LinkDB: CoV_NSP2_N
Original site: CoV_NSP2_N 
#=GF ID   CoV_NSP2_N
#=GF AC   PF19211.2
#=GF DE   Coronavirus replicase NSP2, N-terminal
#=GF PI   Corona_NS2_N;
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   Bateman A
#=GF GA   29.70 29.70;
#=GF TC   30.10 35.90;
#=GF NC   27.30 29.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16227261
#=GF RT   The nsp2 replicase proteins of murine hepatitis virus and severe
#=GF RT   acute respiratory syndrome coronavirus are dispensable for viral
#=GF RT   replication.
#=GF RA   Graham RL, Sims AC, Brockway SM, Baric RS, Denison MR;
#=GF RL   J Virol. 2005;79:13399-13411.
#=GF DR   INTERPRO; IPR043615;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This entry corresponds to the N-terminal region of coronavirus
#=GF CC   non-structural protein 2. NSP2 is encoded by ORF1a/1ab and
#=GF CC   proteolytically released from the pp1a/1ab polyprotein. The
#=GF CC   function of this protein is uncertain. This region contains
#=GF CC   numerous conserved and semi-conserved cysteine residues.
#=GF SQ   79
#=GS A0A0U1UZ20_9ALPC/113-316  AC A0A0U1UZ20.1
#=GS B1PHI7_9ALPC/111-318      AC B1PHI7.1
#=GS R1A_CVPPU/110-310         AC P0C6V2.1
#=GS B8Q8S5_SARS/182-423       AC B8Q8S5.1
#=GS H9TEW9_9ALPC/110-310      AC H9TEW9.1
#=GS E0ZN59_BCHK9/191-395      AC E0ZN59.1
#=GS Q6UZF5_SARS/182-423       AC Q6UZF5.1
#=GS R1A_BCHK5/196-441         AC P0C6T5.1
#=GS F2YDB1_SARS/182-423       AC F2YDB1.1
#=GS R1AB_SARS2/182-423        AC P0DTD1.1
#=GS A0A125R5A3_9ALPC/110-310  AC A0A125R5A3.1
#=GS R1AB_BC279/182-423        AC P0C6V9.1
#=GS B1PHJ4_9ALPC/111-318      AC B1PHJ4.1
#=GS R1AB_FIPV/110-310         AC Q98VG9.2
#=GS A8JNZ0_9ALPC/111-315      AC A8JNZ0.1
#=GS R1A_BC279/182-423         AC P0C6F5.1
#=GS B8Q8U6_SARS/182-423       AC B8Q8U6.1
#=GS A8JNZ1_9ALPC/111-315      AC A8JNZ1.1
#=GS A0A0U1UZA8_9ALPC/111-318  AC A0A0U1UZA8.1
#=GS S5Z1D1_9ALPC/111-314      AC S5Z1D1.1
#=GS A3EXE7_BCHK5/196-441      AC A3EXE7.1
#=GS R1A_SARS2/182-423         AC P0DTC1.1
#=GS R1AB_BC512/111-320        AC P0C6W0.1
#=GS A3EXI9_BCHK9/191-395      AC A3EXI9.1
#=GS R1A_BC512/111-320         AC P0C6F6.1
#=GS A3EXC0_BCHK4/196-440      AC A3EXC0.1
#=GS B1PHI6_9ALPC/111-318      AC B1PHI6.1
#=GS A3EXA2_BCHK4/196-440      AC A3EXA2.1
#=GS A0A0K1Z0N1_SARS/182-423   AC A0A0K1Z0N1.1
#=GS B1PHK0_9ALPC/113-316      AC B1PHK0.1
#=GS B1PHJ3_9ALPC/111-318      AC B1PHJ3.1
#=GS H9TEX0_9ALPC/110-310      AC H9TEX0.1
#=GS B8Q8S4_SARS/182-423       AC B8Q8S4.1
#=GS A0A0K1YZY7_SARS/182-423   AC A0A0K1YZY7.1
#=GS D9J203_9ALPC/111-312      AC D9J203.1
#=GS D9J202_9ALPC/111-312      AC D9J202.1
#=GS E0ZN51_BCHK9/191-395      AC E0ZN51.1
#=GS A0A1X9JQL5_9ALPC/114-205  AC A0A1X9JQL5.1
#=GS R1AB_BCHK5/196-441        AC P0C6W4.1
#=GS A0A096XNJ3_9ALPC/114-290  AC A0A096XNJ3.2
#=GS A0A1X9JQL5_9ALPC/195-287  AC A0A1X9JQL5.1
#=GS A0A023YA54_MERS/196-445   AC A0A023YA54.1
#=GS A0A125R5A4_9ALPC/110-310  AC A0A125R5A4.1
#=GS R1AB_BCHK9/191-395        AC P0C6W5.1
#=GS R1AB_CVH22/112-316        AC P0C6X1.1
#=GS A0A0U1UZC3_9ALPC/112-317  AC A0A0U1UZC3.1
#=GS A0A0P0LKV0_CVH22/112-316  AC A0A0P0LKV0.1
#=GS B1PHK1_9ALPC/113-316      AC B1PHK1.1
#=GS R1A_SARS/182-423          AC P0C6U8.1
#=GS E0XIZ2_9BETC/182-423      AC E0XIZ2.1
#=GS R1AB_BCHK4/196-440        AC P0C6W3.1
#=GS A0A1B3Q5W8_9BETC/191-395  AC A0A1B3Q5W8.1
#=GS A0A0P0ILY9_CVH22/112-316  AC A0A0P0ILY9.1
#=GS A0A0U1UZ65_BCHK4/196-440  AC A0A0U1UZ65.1
#=GS R1A_CVH22/112-316         AC P0C6U2.1
#=GS A0A0U1WHG0_SARS/182-423   AC A0A0U1WHG0.1
#=GS A0A0U1WHK4_SARS/182-423   AC A0A0U1WHK4.1
#=GS A0A0K1RLM9_9ALPC/110-310  AC A0A0K1RLM9.1
#=GS T2B9U0_MERS/194-443       AC T2B9U0.1
#=GS A0A0U1WHG4_9ALPC/111-315  AC A0A0U1WHG4.1
#=GS A0A0U2UMS4_9ALPC/110-310  AC A0A0U2UMS4.1
#=GS R1AB_SARS/182-423         AC P0C6X7.1
#=GS B8Q8U7_SARS/182-423       AC B8Q8U7.1
#=GS T2B9I2_MERS/194-443       AC T2B9I2.1
#=GS U5LR11_9BETC/201-450      AC U5LR11.1
#=GS S5YAF0_9ALPC/111-314      AC S5YAF0.1
#=GS A0A0U1WHD1_9ALPC/113-316  AC A0A0U1WHD1.1
#=GS A0A088DIE1_9BETC/176-416  AC A0A088DIE1.1
#=GS Q0PL14_9ALPC/110-310      AC Q0PL14.1
#=GS U5KNA9_9BETC/201-450      AC U5KNA9.1
#=GS K4K1U5_9ALPC/111-315      AC K4K1U5.1
#=GS A0A059VJE6_9ALPC/111-316  AC A0A059VJE6.1
#=GS R9QTB2_SARS/182-423       AC R9QTB2.1
#=GS F2YDB2_SARS/182-423       AC F2YDB2.1
#=GS R1AB_CVPPU/110-310        AC P0C6Y5.1
#=GS R1A_BCHK4/196-440         AC P0C6T4.1
#=GS A0A240FW17_9ALPC/111-292  AC A0A240FW17.1
#=GS R1A_BCHK9/191-395         AC P0C6T6.1
#=GS A0A0U1WHG1_9ALPC/109-313  AC A0A0U1WHG1.1
A0A0U1UZ20_9ALPC/113-316             ..........gp--VYVDNYMCGANGKPVLPADVWVFQD...YFGDETE-...........LIVNGVKHVKV.......WHVTRT.DIPYQFQSLGAIESIEWL-...TDIPHTL..RSGSKLSAARAVKHSKNVVLSEPLKTLYQACGSPFVTNgstlreavPKPVFAHAYVACK-CGRKSWSVGDWS.GYKSTCCGVFG.KPQCV..-VFGEVVPGDV-..........................FITTSSVGS...GTRY...YNGLTVKHV......VTVDGLACW.............................
B1PHI7_9ALPC/111-318                 ...........t-SIPVDNYMCGANGKPVITEDMWYFCD...YFGDDGDK...........ITINGQEYHKA.......WNVTRS.DVPYQFQNAGTILSIEYV-...STEAHVL..PDGAIAKTAKPPKFSKNVVLSEKCKALYDACGSPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWS.GFKSVCCGTPG.RVLCT..-VFGGVTPGSI-..........................LLTSTRVDAtpgATRY...YHGLTLKHI......CNVDDVACW.............................
R1A_CVPPU/110-310                    ..........ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN-...LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQYA......GDVEGVSIW.............................
B8Q8S5_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
H9TEW9_9ALPC/110-310                 ..........ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDV-...........IEFEGEDYHCA.......WTVVRD.EKPLNQQTLFTIQEIQYN-...LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYRKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDVKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQHA......GDVENVSIW.............................
E0ZN59_BCHK9/191-395                 ...........l-VKPVQDLLGDIKPDLTLEKLTLALSD...YRKDDG--...........YDLPGGFVKIA.......VTVIRK.PVAVVKQTIFTVQGVVEQHvegYYYPYA-..PLGVVKQTKPAAGGPIGKTVEAIMLSLYGTSG------........YKPATPVARLKCSYCDHFGWTPLKDMgTVVCLCGAEYQlTSSCVdaESAGLIKPGCVM..........................LLDKSPGMRvipGNRTyvaFGGAIWSPI......GKVNDVTVW.............................
Q6UZF5_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
R1A_BCHK5/196-441                    ...........d-FTPIDQYMCGKNGKPIAEFAALMASEgitKLADVEAEvksrt.dsdryIVFKNKLYRIV.......WNVQRK.DVAYSKQSAFTMNSIVQLDt.mEDVPRHSftIGSEIQVIAPSTAVQANGHLNLKQRLLYAFYGKQAVSE........PNYIYHSAYVDCTSCGKGSWLTGNAVqGFACDCGAHYCaNDVDL..QSSGLVRKNAVLlttcpcnkdge....ckhtlpqlvsmMTDKCDVEV..vGKTFiltYGGVIYAYM......GCSGGTMHF.............................
F2YDB1_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
R1AB_SARS2/182-423                   ...........y-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKAsctls.eqldfIDTKRGVYCCReheheiaWYTERS.EKSYELQTPFEIKLAKKFDtfnGECPNFVfpLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQ........---MCLSTLMKCDHCGETSWQTGDFV.KATCEFCGTENlTKEGA..TTCGYLPQNAVVkiycpachnsevgpehslaeyhnesgLKTILRKGG...RTIA...FGGCVFSYV......GCHNKCAYW.............................
A0A125R5A3_9ALPC/110-310             ..........ga--IYVDQYMCGADGKPVIEG---EFKD...YFGDEDV-...........IIYEGEEYHCA.......WLTVRD.EKPLCQQNLLTIKEIQYN-...LDIPHKL..PNCAIREVAPPVKKNSKVVLSEDYRKLYDIFGSPFMGNgdslnkcfANLHFIAATLKCP-CGAESSGVGDWT.GFKTACCGLHG.KVKGV..-TLGAVKPGDA-..........................VITSMSAGK...GVKF...FANSVLQYA......GDVENVSVW.............................
R1AB_BC279/182-423                   ...........f-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKSmctls.eqldyIESKRGVYCCReheheivWFTERS.EKSYERQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVATPQECND........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEQCGTE-.NLVCEgpTTCGYLPANAVVkmpcpacqdpevgpehsvadyhnhsnIETRLRKGG...RTKC...FGGCVFAYV......GCYNKRAYW.............................
B1PHJ4_9ALPC/111-318                 ...........t-SIPVDNYMCGANGKPVLPEDMWCFCD...YFGDDGDN...........ITVNGQAYHKA.......WNVTRG.DVPYQFQNASTILSIEYL-...ADEKHVL..PDGAVAKSAKPPKFSKNIVLSEKYKALYDACGNPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWA.GFKSVCCGIPG.RVLCT..-VFGGVAPGSV-..........................LLTSTRVDAspgATRY...YHGLTLKHI......CNVDGVACW.............................
R1AB_FIPV/110-310                    ..........ga--IYVDQYMCGADGKPVIEG---EFKD...YFGDEDV-...........IIYEGEEYHCA.......WLTVRD.EKPLWQQTLLTIREIQYN-...LDIPHKL..PNCAIREVAPPVKKNSKVVLSEEYRKLYDIFGSPFMGNgdslntcfDSLHFIAATLKCP-CGAESSGVGDWT.GFKTACCGLHG.KVKGV..-TLGAVKPGDA-..........................IVTSMSAGK...GVKF...FANSVLQYA......GDVENVSVW.............................
A8JNZ0_9ALPC/111-315                 ............DVVPVDNYMCGADGKPAVPSEQWSFVE...HFDDDTDE...........ITVNGVTFRHA.......WNTVRA.DDPYEKQGLLSIKFIEYI-...SNVPHKL..PNGSVLGVAGTPKKRKAVVLDEKYSKLYDACGVPFVTNgksisevvTKPLFLHALVECK-CGNESWTVGDWT.GFKTTCCGVTG.KVITL..-AVGDVTPGDI-..........................VFTTPGAGK...GTKF...FCGLVLTFV......DTLEGVSAW.............................
R1A_BC279/182-423                    ...........f-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKSmctls.eqldyIESKRGVYCCReheheivWFTERS.EKSYERQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVATPQECND........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEQCGTE-.NLVCEgpTTCGYLPANAVVkmpcpacqdpevgpehsvadyhnhsnIETRLRKGG...RTKC...FGGCVFAYV......GCYNKRAYW.............................
B8Q8U6_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
A8JNZ1_9ALPC/111-315                 ............DVVPVDNYMCGADGKPAVPSEQWSFVE...HFDDDTDE...........ITVNGVTFRHA.......WNTVRA.DDPYEKQGLLSIKFIEYI-...SNVPHKL..PNGSVLGVAGTPKKRKAVVLDEKYSKLYDACGVPFVTNgksisevvTKPLFLHALVECK-CGNESWTVGDWT.GFKTTCCGVTG.KVITL..-AVGDVTPGDI-..........................VFTTPGAGK...GTKF...FCGLVLTFV......DTLEGVSAW.............................
A0A0U1UZA8_9ALPC/111-318             ...........t-SIPVDNYMCGANGKPVLPEDMWCFCD...YFGDDGDN...........ITVNGQAYHKA.......WNVTRS.DVPYQFQNASTILSIEYL-...ADEKHVL..PDGAVAKTAKPPKFSKNIVLSEKYKALYDACGSPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWA.GFKSVCCGIPG.RVLCT..-VFGGVAPGSV-..........................LLTSTRVDAspgAARY...YHGLTLKHI......CNVDGVACW.............................
S5Z1D1_9ALPC/111-314                 ............NTIYVDQYLCGADGKPVVPEEFWDFKD...YFVDDDQ-...........VVVNGTTYIKA.......WVVERA.NVAYEAQNVTAINGITYC-...AKIPHTL..PDGSVVRVARKPKIKKSIVLSDVYKPLLEGLGAPFVKNgdtlasilTEPVFLHALVKCT-CGKTMWTVGDWS.CYKSLCCGVVC.KPLCN..-VAGIVNPGSA-..........................VVTRTGLGS...GIKY...YCGMFLRHI......LDVDGVSVW.............................
A3EXE7_BCHK5/196-441                 ...........d-FTPIDQYMCGKNGKPIAEFAALMASEgitKLADVEAEvksrt.dsdryIVLKNKLYRIV.......WNVQRK.DVAYSKQSAFTMNSIVQLDt.mEDVPRHSftIGSEIQVIAPSTAVQANGHLNLKQRLLYAFYGKQAVSE........PNYIYHSAYVDCTSCGKGSWLTGNAVqGFACDCGAHYCaNDVDL..QSSGLVRKNAVLlttcpcnkdge....ckhtlpqlvsmMTDKCDVEV..vGKTFiltYGGVIYAYM......GCSGGTMHF.............................
R1A_SARS2/182-423                    ...........y-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKAsctls.eqldfIDTKRGVYCCReheheiaWYTERS.EKSYELQTPFEIKLAKKFDtfnGECPNFVfpLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQ........---MCLSTLMKCDHCGETSWQTGDFV.KATCEFCGTENlTKEGA..TTCGYLPQNAVVkiycpachnsevgpehslaeyhnesgLKTILRKGG...RTIA...FGGCVFSYV......GCHNKCAYW.............................
R1AB_BC512/111-320                   ...........t-TIPVDQFMCGADGAPVIQEGDWTFMD...YFQDSNQ-...........FTLNGITYVKA.......WDVDRK.PNDYAKQNVTCIRRITYI-...TDHRHVL..ADGTTMKTARHPKVNKSVVLDSPFDQIYKEVGSPFMGNgstfvemlKDPAFFHALITCE-CGRSEWTVGDWK.GYNSLCCNIKC.KPITI..-VTPKAVPGAV-..........................VITKAGIGA...GLKC...YNNVFLKHIidlvvpGTNLGWGVW.............................
A3EXI9_BCHK9/191-395                 ...........l-VKPVQDLLGDIRPDFTLEELTLCLSD...YRTDDG--...........YDLLGGYVKVA.......VKVVRK.PVPVVKQTIFTVQGVIEQCvegYYYPFP-..PMSAVKHTKPRSDKPLGKTVDSIMLSLYGTSG------........YNPATPVVRLRCSHCDFYGWVPLKDMgTVSCSCSAVHQlTSSCIdaESAGAIKPGCVM..........................LLDKSPGMRvipGNRTyvaFGGAIWSPI......GKVGDVTVW.............................
R1A_BC512/111-320                    ...........t-TIPVDQFMCGADGAPVIQEGDWTFMD...YFQDSNQ-...........FTLNGITYVKA.......WDVDRK.PNDYAKQNVTCIRRITYI-...TDHRHVL..ADGTTMKTARHPKVNKSVVLDSPFDQIYKEVGSPFMGNgstfvemlKDPAFFHALITCE-CGRSEWTVGDWK.GYNSLCCNIKC.KPITI..-VTPKAVPGAV-..........................VITKAGIGA...GLKC...YNNVFLKHIidlvvpGTNLGWGVW.............................
A3EXC0_BCHK4/196-440                 ...........d-CVPVDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dsdrfIVLNKKLYRVV.......WNVTRR.NVPYSKQTAFTVVSVVQFDd.kESVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLYTFYGKDAVQQ........PGYIYHSAYVDCNACGKGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPRNALFlancpcannga....cshsaaqvysiLDGKACVEV..gGKSFtltFGGVVYAYM......GCCDGTMYF.............................
B1PHI6_9ALPC/111-318                 ...........t-SIPVDNYMCGANGKPVITEDMWYFCD...YFGDDGDK...........ITINGQEYHKA.......WNVTRS.DVPYQFQNAGTILSIEYV-...STEAHVL..PDGAIAKTAKPPKFSKNVVLSEKCKALYDACGSPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWS.GFKSVCCGTPG.RVLCT..-VFGGVTPGSI-..........................LLTSTRVDAtpgATRY...YHGLTLKHI......CNVDDVACW.............................
A3EXA2_BCHK4/196-440                 ............DCIPIDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dsdrfIVLNKKLYRVV.......WNVTRR.NVPYPKQTAFTIVSVVQCDd.kDSVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLYTFYGKDAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPRNALFlancpcannga....cshsaaqvyniLDGKACVEV..gGKSFtltFGGVVYAYM......GCCDGTMYF.............................
A0A0K1Z0N1_SARS/182-423              ...........v-TRYVDNNFCGPDGYPLE-----CIKG...LLARAGKSmctls.eqldfIESKRGVYCCReheheiaWYTERS.DKSYEHQTPFDIKSAKKFDtfkEECPKFVfpLNSTVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCSHCDEVSWQTCDFL.KATCEHCGTEN.LVVEG.pTTCGYLPINAVVkmpcpacqnkevgpehsvadyhnysnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW.............................
B1PHK0_9ALPC/113-316                 ..........sp--VYVDNYMCGANGKPVLPADVWVYQD...YFGEETE-...........LIVNGVKHVKV.......WHVTRT.DIPYQFQSLGAIESIEWL-...TDIPHTL..RNGSRLSAARAVKHSKNVVLSEPLKTLYQACGSPFVTNgstlreavPKPVFAHAYVACK-CGRKAWSVGDWS.GYKSTCCGVFG.KPQCV..-VFGEVVPGDV-..........................FITTSSVGS...GTRY...YNGLTVKHV......VTVDGLACW.............................
B1PHJ3_9ALPC/111-318                 ...........t-SIPVDNYMCGANGKPVLPEDMWCFCD...YFGDDGDN...........ITVNGQAYHKA.......WNVTRG.DVPYQFQNASTILSIEYL-...ADEKHVL..PDGAVAKSAKPPKFSKNIVLSEKYKALYDACGNPFVTNgtnvlevvTNPIFAHGFVQCK-CGSKHWTTGDWA.GFKSVCCGIPG.RVLCT..-VFGGVAPGSV-..........................LLTSTRVDAspgATRY...YHGLTLKHI......CNVDGVACW.............................
H9TEX0_9ALPC/110-310                 ..........ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDV-...........IEFEGEDYHCA.......WTVVRD.EKPLNQQTLFTIQEIQYN-...LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYRKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDVKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQHA......GDVENVSIW.............................
B8Q8S4_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
A0A0K1YZY7_SARS/182-423              ...........v-TRYVDNNFCGPDGYPLE-----CIKG...LLARAGKSmctls.eqldfIESKRGVYCCReheheiaWYTERS.DKSYEHQTPFDIKSAKKFDtfkEECPKFVfpLNSTVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCSHCDEVSWQTCDFL.KATCEHCGTEN.LVVEG.pTTCGYLPINAVVkmpcpacqnkevgpehsvadyhnysnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW.............................
D9J203_9ALPC/111-312                 ...........t-VVHVDQFLCGADGKPVRQG---DMKD...YFGDLEE-...........IVIDGITYQHA.......WDVVRDvEVPHAKQTALNVQSIMYL-...MDVDHKL..VNGATRQRAAPVKISSKVCLTEPYNSLYKHFGSPYMQNggnlnecfAKLNFIVANVKCK-CGGESSGVGDWT.GFKSACCGTPG.KVIGV..-SIGDASVGEA-..........................VITSKGCGT...GTKF...YAGAVLKYV......GDAEGVSVW.............................
D9J202_9ALPC/111-312                 ...........t-VVHVDQFLCGADGKPVRQG---DMKD...YFGDLEE-...........IVIDGITYQHA.......WDVVRDvEVPHAKQTALNVQSIMYL-...MDVDHKL..VNGATRQRAAPVKISSKVCLTEPYNSLYKHFGSPYMQNggnlnecfAKLNFIVANVKCK-CGGESSGVGDWT.GFKSACCGTPG.KVIGV..-SIGDASVGEA-..........................VITSKGCGT...GTKF...YAGAVLKYV......GDAEGVSVW.............................
E0ZN51_BCHK9/191-395                 ...........l-VKPVLELLGGIKPDLTLEKLTLALSE...YRNSDG--...........YDLPGGFVRVA.......VSVIRK.PVPVVKQTIFTVQGVVEQHvegFYYPYS-..TMSVVKHTKPRSDKPLGKTVESIMLSLYGTSG------........YSPATPVVRLRCSYCDFYGWVPPRDMgTVVCSCGAEFQlTSACVdaESAGAIKPGCVM..........................LLDRSPGMRlipGNRIyvaFGGAIWSPI......GTVNGVSVW.............................
A0A1X9JQL5_9ALPC/114-205             ..........np--IFVDQYLCGADGTPVK--RDVEFKN...YFTDGDT-...........YVEPGKTYKLV.......WNVERK.PGDL---TLSGILSIKYL-...SDKPHKL..RDGVVQEVADAVS-------------------------........--------------------------.-----------.-----..------------..........................---------...----...---------......---------elndtkql.....................
R1AB_BCHK5/196-441                   ...........d-FTPIDQYMCGKNGKPIAEFAALMASEgitKLADVEAEvksrt.dsdryIVFKNKLYRIV.......WNVQRK.DVAYSKQSAFTMNSIVQLDt.mEDVPRHSftIGSEIQVIAPSTAVQANGHLNLKQRLLYAFYGKQAVSE........PNYIYHSAYVDCTSCGKGSWLTGNAVqGFACDCGAHYCaNDVDL..QSSGLVRKNAVLlttcpcnkdge....ckhtlpqlvsmMTDKCDVEV..vGKTFiltYGGVIYAYM......GCSGGTMHF.............................
A0A096XNJ3_9ALPC/114-290             ...........n-PIYVDQYLCGPDGTPVKKG--LEFKD...YFMNGGDI...........YVEPGKTYVRV.......WDVERK.QDDL---TLDGILSIKYL-...SDKPHKL..RDGAIQGVADAVSE-----LN-------DTN-------........QMVRFIHAFVSCP-CGKSAFTVGSWM.GFATVCCGKIVkTPMCV..KFSGEAGSIFAL..........................PVGSRGFSA..nGKRS...YAGAEFQFC......CELSGVEIW.............................
A0A1X9JQL5_9ALPC/195-287             avselndtkqlv---------------------------...--------...........-----------.......------.-------------------...-------..--------------------------------------........---RFIHGFVSCP-CGKSAFTVGGWN.GFATVCCGVTVkSPICV..KFSGKA--GSIF.........................aLPLGSRVFG...TKRI...YAGAEFQYC......CDLSGVEIW.............................
A0A023YA54_MERS/196-445              ...........d-FIPIDQFMCGKDGAPVPDYATLAASEnliSLADVATDvsara.dsdgyIDFKSKLYRIV.......WHVERK.NVPYAKQTIFTINSVVQCDgiqDVPPHTF.tLGGKVDLIVPRNKWTGKTALNLKQKILYTFYGKDALDN........HSYIYHSAYADCTSCGKGSWLTGNAVqGFACDCGAQYSaNDVEL..QSSGVVNPNAIFcatcpfakgdscsssckhtlaqmvsqLSEKCDVAP..dGKSFtlaFGGVVYAYL......GCLEGTMYF.............................
A0A125R5A4_9ALPC/110-310             ..........ga--IYVDQYMCGADGKPVIEG---EFKD...YFGDEDV-...........IIYEGEEYHCA.......WLTVRD.EKPLCQQNLLTIKEIQYN-...LDIPHKL..PNCAIREVAPPVKKNSKVVLSEDYRKLYDIFGSPFMGNgdslnkcfANLHFIAATLKCP-CGAESSGVGDWT.GFKTACCGLHG.KVKGV..-TLGAVKPGDA-..........................VITSMSAGK...GVKF...FANSVLQYA......GDVENVSVW.............................
R1AB_BCHK9/191-395                   ...........l-VEPVMKLLGVIKSDFTLEQLLAALGK...YRTEDG--...........YDLPDGYVKVA.......IKVGRK.AVPVLKQSIFTVVGVTEQLvpgYYYPFS-..TSSVVEHTKPTRGGPVGKTVEAVMLSLYGTNN------........YNPATPVARLKCSYCDYYGWTPLKDIgTVNCLCGAEFQlTSSCVdaESAGVIKPGCVM..........................LLDKSPGMRlipGNRTyvsFGGAIWSPI......GKVNGVTVW.............................
R1AB_CVH22/112-316                   ............NVTYTDQYLCGADGKPVMSEDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYVH...GDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnileafTKPVFISALVQCT-CGTKSWSVGDWT.GFKSSCCNVIS.NKLCV..-VPGNVKPGDA-..........................VITTQQAGA...GIKY...FCGMTLKFV......ANIEGVSVW.............................
A0A0U1UZC3_9ALPC/112-317             ..........pp--IYVDNYLCGADGTPVVQESMWSYTD...HFGEDCDE...........ITLCGITYVHA.......WNVQRA.DVPYEQQNVTSIFSIEYL-...LDVDHAL..QNGAVLNVASGVKYKKSVVLSEGFKKLYDACGVPAVQNgntlvdilTKPAFFHAIVSCS-CGLSSYTVGDWKiGFRSLCCGKRL.EPITV..-VVGDVKPGDI-..........................VVTSANAGD...GVRY...FNGLTLQYV......GDWEGVSCW.............................
A0A0P0LKV0_CVH22/112-316             ...........t-VTYTDQYLCGADGKPVINEDLWQFVD...YFGENEE-...........VVINGQTYVCA.......WLTKRK.PLDHKRQNNLAIEEINYVR...GDALHTL..RNGSVLETAKDLKTSSKVVLSAELDKLYKMLGSPFMTNgstileaiVKPVFISALVQCT-CGKKGWSVGDWT.GFKSSCCNNLS.KRLCV..-VPGVVKPGDA-..........................VITTQKAGV...GIKY...FCGMTLKFV......ASIEGVSVW.............................
B1PHK1_9ALPC/113-316                 ..........sp--VYVDNYMCGANGKPVLPADVWVYQD...YFGEETE-...........LIVNGVKHVKV.......WHVTRT.DIPYQFQSLGAIESIEWL-...TDIPHTL..RNGSRLSAARAVKHSKNVVLSEPLKTLYQACGSPFVTNgstlreavPKPVFAHAYVACK-CGRKAWSVGDWS.GYKSTCCGVFG.KPQCV..-VFGEVVPGDV-..........................FITTSSVGS...GTRY...YNGLTVKHV......VTVDGLACW.............................
R1A_SARS/182-423                     ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
E0XIZ2_9BETC/182-423                 ...........y-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKSsapla.eqldfLESKRGVYCCReheheiaWYTERS.DKSYELQTPFDITNAKKFDsfkGECPKFVfpLNSTVKVLQPRVEKKKTEGFLGRIRTVYQVASPGEC--........-NSMHLSTYMNCNHCGEKSWQTCDFL.TATCEMCGNQ-.NTVEEgpTTCGYVPSNAVVkmvcpacqnpeigpdhsvadyhnnskIETRLRKGG...RIKS...FGGCVFSYV......GCYNKRAFW.............................
R1AB_BCHK4/196-440                   ............DCIPIDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dsdrfIVLNKKLYRVV.......WNVTRR.NVPYPKQTAFTIVSVVQCDd.kDSVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLYTFYGKDAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPRNALFlancpcannga....cshsaaqvyniLDGKACVEV..gGKSFtltFGGVVYAYM......GCCDGTMYF.............................
A0A1B3Q5W8_9BETC/191-395             ..........la--APIKEVLGGKGAGMSLVELTKFLGK...YRTADG--...........YELPSGIVKVA.......VKVVRK.NLPVSKQSIFTVLGVTERVvdgFYYPYS-..TNSVVSYTKPRAGATVGNTVQSVMLSMYGTEA------........YNPVTPVVRLRCSSCDFYGWVPVKDLgCVTCSCAAVHQiTSSCIdaESAGLIKQGAVM..........................LVDRSPSMRvvpGNRLyvaFGGAIWSPI......GKVNGVQVW.............................
A0A0P0ILY9_CVH22/112-316             ...........t-VTYTDQYLCGADGKPVINEDLWQFVD...YFGENEE-...........VVINGQTYVCA.......WLTKRK.PLDHKRQNNLAIEEINYVR...GDALHTL..RNGSVLETAKDLKTSSKVVLSAELDKLYKMLGSPFMTNgstileaiVKPVFISALVQCT-CGKKGWSVGDWT.GFKSSCCNNLS.KRLCV..-VPGVVKPGDA-..........................VITTQKAGV...GIKY...FCGMTLKFV......ASIEGVSVW.............................
A0A0U1UZ65_BCHK4/196-440             ............DCIPVDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dldrfIVLNKKLYRVV.......WNVTRR.NVPYSKQTAFTVVSVVQCDd.kESVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLHTFYGKEAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPKNALFlancpcanngs....cshsaaqvysiLDGKACVEF..gGKSFtltFGGVVYAYM......GCCDGTMYF.............................
R1A_CVH22/112-316                    ............NVTYTDQYLCGADGKPVMSEDLWQFVD...HFGENEE-...........IIINGHTYVCA.......WLTKRK.PLDYKRQNNLAIEEIEYVH...GDALHTL..RNGSVLEMAKEVKTSSKVVLSDALDKLYKVFGSPVMTNgsnileafTKPVFISALVQCT-CGTKSWSVGDWT.GFKSSCCNVIS.NKLCV..-VPGNVKPGDA-..........................VITTQQAGA...GIKY...FCGMTLKFV......ANIEGVSVW.............................
A0A0U1WHG0_SARS/182-423              ...........v-TRYVDNNFCGPDGYPLD-----CIKD...LLARAGKSmctlp.eqldfIESKRGVYCCReheheiaWYTERS.DKSYEHQTPFEVKIAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKNTEGFMGRIRSVYQVATPNECND........---MHLSVFMKCNHCDEASWQTCDFL.KATCEYCGTE-.NPVSEgpTTCGYLPTNAVVkmpcpacqnkevgpehsvadyhnhssIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW.............................
A0A0U1WHK4_SARS/182-423              ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdhehevaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTE-.NSIAEgpTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRRGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
A0A0K1RLM9_9ALPC/110-310             ...........g-VIYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN-...LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMNAGK...GVKF...FANCVLQYA......GDVEGVSIW.............................
T2B9U0_MERS/194-443                  ............DVTPVDQYMCGVDGKPISAYAFLMAKDgitKLADVEADvaara.ddegfITLKNNLYRLV.......WHVERK.DVPYPKQSIFTINSVVQKDgveNTPPHYF.tLGCKILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLEN........PTYIYHSAFIECGSCGNDSWLTGNAIqGFACGCGASYTaNDVEV..QSSGMIKPNALLcatcpfakgdscssnckhsvaqlvsyLSERCNVIA..dSKSFtliFGGVAYAYF......GCEEGTMYF.............................
A0A0U1WHG4_9ALPC/111-315             ............NTVYVDNYMCGSNGVPVLPEDQWEFVD...YFGELTE-...........VSIGDTTYIKA.......WNVDRV.EGPYKSQTLLSINAISYC-...GEVIHAL..ADGSTMSYATAVKKNSKTVVNKTYQKLYDNIGVPFVTNgkvlteiiPKPVFNHGLVKCH-CGKVSWTVGDWS.CYKSTCCGTVC.KPIAI..-VNGDVNPGDV-..........................VITSKQVAT..nGVKY...YNGMVLKYV......DTIEDVHLW.............................
A0A0U2UMS4_9ALPC/110-310             ..........gi--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN-...MDIPHKL..SNCAIRHVAPPVKKNSKIVLSEDYKKLYEIFGSPFMGNgdclskcfNTLHFIVATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQYA......GDVEGVSIW.............................
R1AB_SARS/182-423                    ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
B8Q8U7_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
T2B9I2_MERS/194-443                  ............DVTPVDQYMCGVDGKPISAYAFLMAKDgitKLADVEADvaara.ddegfITLKNNLYRLV.......WHVERK.DVPYPKQSIFTINSVVQKDgveNTPPHYF.tLGCKILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLEN........PTYIYHSAFIECGSCGNDSWLTGNAIqGFACGCGASYTaNDVEV..QSSGMIKPNALLcatcpfakgdscssnckhsvaqlvsyLSERCNVIA..dSKSFtliFGGVAYAYF......GCEEGTMYF.............................
U5LR11_9BETC/201-450                 ............DVIPVDQYMCGFDGSPIKPYLDLANKEgltKLADVEADvcsrv.dkqgfLIFKGTTYRVV.......WFTERK.DVDYSKQTLFTVICVMQRNg.vHDIPAHPftLGSKVEQLKPHVAKGNLVGLTLKAKILYTMYGEDAVEE........PSYIYHSAFVDCVKCNEGKWCTGNAVaGFACECGAAYTaKQVLL..QSSGLVKSNALFcatcpfaqgdrcsldckhtvpqvvsyLSEKCVVFP..sGKSFvlaFGGALYTYM......GCAEGTMYF.............................
S5YAF0_9ALPC/111-314                 ............NTIYVDQYLCGADGKPVVPEEFWDFKD...YFVDDDQ-...........VVVNGTTYIKA.......WVVERA.NVAYEAQNVTAINGITYC-...AKIPHTL..PDGSVVRVARKPKIKKSIVLSDVYKPLLEGLGAPFVKNgdtlasilTEPVFLHALVKCT-CGKTMWTVGDWS.CYKSLCCGVVC.KPLCN..-VAGIVNPGSA-..........................VVTRTGLGS...GIKY...YCGMFLRHI......LDVDGVSVW.............................
A0A0U1WHD1_9ALPC/113-316             ..........ep--VYVDNYMCGANGKPVLPADVWCFQD...YFGDETE-...........LVVNGVRHVKA.......WDVVRT.NLPYQFQSTGAIESIIWL-...SDVPHVL..RNGSKLSVCKAPKFSKNVKLSEPLNTLYQACGSPFVSNgtdlagavGKPVFAHSYVACK-CGSKCWSVGDWS.GYKSTCCGTFG.KVLCT..-VFGDVVPGDV-..........................LMTSAAVGS...GTRY...YNGLTIKHV......VTVQNIACW.............................
A0A088DIE1_9BETC/176-416             .........dfh--RYVDNYYCTGDGKPLP-----CIVT...LLEKAGHAnkplddamdylRGLNRMGQPCRdhdhervWEVERD.NAPYPEQSLFSISAIKTL-...GEIPHCVfaPDCAVKVMKPRKVKRGADGFMTKLRRVYNINGFDEV--........-KPMALCALHYCEDCGMEMWCHSNFE.EAYCPCGKIYT.NTPCT.lTSAGYVVEGSVVampcdacksdsd.hsngtfydsckylAEDKAEPGN...RENFv.yFGGCCFAYV......GCRNGNAIW.............................
Q0PL14_9ALPC/110-310                 ...........g-VIYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN-...LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQYA......GDVEGVSIW.............................
U5KNA9_9BETC/201-450                 ............DVIPVDQYMCGFDGSPIKPYLDLANKEgltKLADVEADvcsrv.dkqgfLIFKGTTYRVV.......WFTERK.DVDYSKQTLFTVICVMQRNg.vHDIPAHPftLGSKVEQLKPHVAKGNLVGLTLKAKILYTMYGEDAVEE........PSYIYHSAFVDCVKCNEGKWCTGNAVaGFACECGAAYTaKQVLL..QSSGLVKSNALFcatcpfaqgdrcsldckhtvpqvvsyLSEKCVVFP..sGKSFvlaFGGALYTYM......GCAEGTMYF.............................
K4K1U5_9ALPC/111-315                 ...........t-TVFVDNFLCGANGLPACSEQEWEFKD...HFGELDE-...........VTINGTTFVKA.......WNVDRT.PGPYSTQNLLSINSISWC-...GEIPHSL..ADGSIRRVAKVVKKSKSVLLGKQFQQLYDSVGSPFVTNgknlsdvlVKPIYCHALVKCQ-CGKTSWTVGDWS.CYKSMCCGFNC.KPLAI..-VNGEVVPGDV-..........................LVTSDKVSA..sGTKY...YNGMVLKFV......DKIDNACLW.............................
A0A059VJE6_9ALPC/111-316             ...........n-IVPVDQYMCGADGKPVLQESEWEYTD...FFADSEDG..........qLNIAGITYVKA.......WIVERS.DVSYASQNLTSIKSITYC-...STYEHTF..PDGTAMKVARTPKIKKTVVLSEPLATIYREIGSPFVDNgsdarsiiKRPVFLHAFVKCK-CGSYHWTVGDWT.SYVSTCCGFKC.KPVLV..-ASCSATPGSV-..........................VVTRAGAGT...GVKY...YNNMFLRHV......ADIDGLAFW.............................
R9QTB2_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLE-----CIKD...LLARAGKSmctls.eqldyIESKRGVYCCReheheivWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVATPQECND........---MHLSTLMKCNHCDEVSWQTCDFI.KATCEQCGTE-.NPVCEgpTTCGYLPTNAVVkmpcpacqdpevgpehsvadyhnhsnIETRLRKGG...RTKC...FGGCVFSYV......GCYNKRAYW.............................
F2YDB2_SARS/182-423                  ...........v-TRYVDNNFCGPDGYPLD-----CIKD...FLARAGKSmctls.eqldyIESKRGVYCCRdheheiaWFTERS.DKSYEHQTPFEIKSAKKFDtfkGECPKFVfpLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN........---MHLSTLMKCNHCDEVSWQTCDFL.KATCEHCGTEN.LVIEG.pTTCGYLPTNAVVkmpcpacqdpeigpehsvadyhnhsnIETRLRKGG...RTRC...FGGCVFAYV......GCYNKRAYW.............................
R1AB_CVPPU/110-310                   ..........ga--IYVDQYMCGADGKPVIEG---DFKD...YFGDEDI-...........IEFEGEEYHCA.......WTTVRD.EKPLNQQTLFTIQEIQYN-...LDIPHKL..PNCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNgdclskcfDTLHFIAATLRCP-CGSESSGVGDWT.GFKTACCGLSG.KVKGV..-TLGDIKPGDA-..........................VVTSMSAGK...GVKF...FANCVLQYA......GDVEGVSIW.............................
R1A_BCHK4/196-440                    ............DCIPIDQYMCGKNGKPIADYAKIVAKEgltTLADIEVDvksrm.dsdrfIVLNKKLYRVV.......WNVTRR.NVPYPKQTAFTIVSVVQCDd.kDSVPEHTftIGSQILMVSP-LKATNNKNFNLKQRLLYTFYGKDAVQQ........PGYIYHSAYVDCNACGRGTWCTGNAIqGFACDCGANYSaNDVDL..QSSGLVPRNALFlancpcannga....cshsaaqvyniLDGKACVEV..gGKSFtltFGGVVYAYM......GCCDGTMYF.............................
A0A240FW17_9ALPC/111-292             ...........k-VVYVDNYLCGNNGKPVVPKDKWKILS...K---GQQG...........LLADNVYYKVV.......WDVKRD.DVPYEKQNMSSIVSIRYL-...IDIPHFL..ADGAVREKKRPPQDYTTML----------VKGFPFLMA........YDWKFVNHAVKCGKCDNHVVEAGAFE.SVITSCCRDEI.VHQGV..---VTAKAGEL-..........................V--------...----...---------......---------ltplsnkklilvgstvlrnigtahnlsiw
R1A_BCHK9/191-395                    ...........l-VEPVMKLLGVIKSDFTLEQLLAALGK...YRTEDG--...........YDLPDGYVKVA.......IKVGRK.AVPVLKQSIFTVVGVTEQLvpgYYYPFS-..TSSVVEHTKPTRGGPVGKTVEAVMLSLYGTNN------........YNPATPVARLKCSYCDYYGWTPLKDIgTVNCLCGAEFQlTSSCVdaESAGVIKPGCVM..........................LLDKSPGMRlipGNRTyvsFGGAIWSPI......GKVNGVTVW.............................
A0A0U1WHG1_9ALPC/109-313             ..........ae--VYVDNYMCDQTGKPVLAADVWTFKD...YFGESDT-...........IVIDGVVYRKA.......WEVVRL.DVPYKAQSVSAISSIEWL-...CGVQHVL..PSGTVLDVAKSVSKSKVVLLSDPYADIYDQVGSPFMTNgknlleivVKPCFLHGYVKCN-CGNTHWAVGDWRaGYKSVCCGLNC.NPICV..-AAGYVEPGDV-..........................LFTSKGAGT...GLKY...YKGLTLKFV......GEVENVAVW.............................
#=GC seq_cons                        ...........s.shaVDpahCGsDGcPlh.....shpD...ahu-ssp............IphpsthYpps.......WhspRs.-hsYppQohhsIpulphh....s-hP+hl..hsuslptlsPtlcpppshslstch+pLYshhGsshhsN.........p.hahsuhlcCs.CGptoWssGDah.uapssCCGs.s.pslsl...osGhl.sssl...........................lhTphpsGs...Gs+a...FuGslhpal......GshsssuhW.............................
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