GenomeNet

Database: Pfam
Entry: CoV_NSP8
LinkDB: CoV_NSP8
Original site: CoV_NSP8 
#=GF ID   CoV_NSP8
#=GF AC   PF08717.12
#=GF DE   Coronavirus replicase NSP8
#=GF PI   nsp8;
#=GF AU   Mistry J;0000-0003-2479-5322
#=GF AU   Chuguransky S;0000-0002-0520-0736
#=GF SE   pdb_2ahm
#=GF GA   72.80 72.80;
#=GF TC   119.00 119.00;
#=GF NC   26.70 25.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   16228002
#=GF RT   Insights into SARS-CoV transcription and replication from the
#=GF RT   structure of the nsp7-nsp8 hexadecamer. 
#=GF RA   Zhai Y, Sun F, Li X, Pang H, Xu X, Bartlam M, Rao Z; 
#=GF RL   Nat Struct Mol Biol. 2005;12:980-986.
#=GF RN   [2]
#=GF RM   31138817
#=GF RT   Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and
#=GF RT   nsp8 co-factors.
#=GF RA   Kirchdoerfer RN, Ward AB;
#=GF RL   Nat Commun. 2019;10:2342.
#=GF RN   [3]
#=GF RM   30918070
#=GF RT   Identification and Characterization of a Human Coronavirus 229E
#=GF RT   Nonstructural Protein 8-Associated RNA 3'-Terminal
#=GF RT   Adenylyltransferase Activity.
#=GF RA   Tvarogova J, Madhugiri R, Bylapudi G, Ferguson LJ, Karl N,
#=GF RA   Ziebuhr J;
#=GF RL   J Virol. 2019; [Epub ahead of print]
#=GF RN   [4]
#=GF RM   22039154
#=GF RT   The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric
#=GF RT   RNA polymerase capable of both de novo initiation and primer
#=GF RT   extension.
#=GF RA   te Velthuis AJ, van den Worm SH, Snijder EJ;
#=GF RL   Nucleic Acids Res. 2012;40:1737-1747.
#=GF DR   INTERPRO; IPR014829;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   Viral NSP8 (non structural protein 8) forms a hexadecameric
#=GF CC   supercomplex with NSP7 that adopts a hollow cylinder-like
#=GF CC   structure [1]. The dimensions of the central channel and
#=GF CC   positive electrostatic properties of the cylinder imply that it
#=GF CC   confers processivity on RNA-dependent RNA polymerase [1]. NSP7
#=GF CC   and NSP8 heterodimers play a role in the stabilisation of NSP12
#=GF CC   regions involved in RNA binding and are essential for a highly
#=GF CC   active NSP12 polymerase complex [2]. It has been demonstrated
#=GF CC   that NSP8 acts as an oligo(U)-templated polyadenylyltransferase
#=GF CC   but also has robust (mono/oligo) adenylate transferase
#=GF CC   activities [3]. NSP8 has N- and C-terminal D/ExD/E conserved
#=GF CC   motifs, being the N-terminal motif critical for RNA polymerase
#=GF CC   activity as these residues are part of the Mg2-binding active
#=GF CC   site [4].
#=GF SQ   111
#=GS Q6UZF5_SARS/3920-4116       AC Q6UZF5.1
#=GS A0A0U1UZ20_9ALPC/3775-3968  AC A0A0U1UZ20.1
#=GS B8Q8U6_SARS/3920-4116       AC B8Q8U6.1
#=GS D9J203_9ALPC/3547-3742      AC D9J203.1
#=GS R1AB_BC512/3674-3868        AC P0C6W0.1
#=GS R1A_IBVB/3463-3671          AC P0C6V3.1
#=GS B8Q8S5_SARS/3920-4116       AC B8Q8S5.1
#=GS R1A_SARS2/3943-4139         AC P0DTC1.1
#=GS R1A_CVM2/3959-4154          AC P0C6U9.1
#=GS A0A0U1UZ65_BCHK4/3981-4178  AC A0A0U1UZ65.1
#=GS R1A_CVMJH/4017-4212         AC P0C6V1.1
#=GS R1AB_CVHOC/3926-4121        AC P0C6X6.1
#=GS B1PHI6_9ALPC/3868-4062      AC B1PHI6.1
#=GS R1AB_SARS/3920-4116         AC P0C6X7.1
#=GS R1AB_SARS/3920-4116         DR PDB; 2AHM E; 43-197;
#=GS R1AB_SARS/3920-4116         DR PDB; 2AHM G; 6-196;
#=GS R1AB_SARS/3920-4116         DR PDB; 2AHM H; 7-197;
#=GS R1AB_SARS/3920-4116         DR PDB; 5F22 B; 82-196;
#=GS R1AB_SARS/3920-4116         DR PDB; 2AHM F; 55-197;
#=GS A0A059VJE6_9ALPC/3663-3857  AC A0A059VJE6.1
#=GS R1AB_CVMA5/4011-4206        AC P0C6X9.1
#=GS S5Z1D1_9ALPC/3705-3900      AC S5Z1D1.1
#=GS Q0PL14_9ALPC/3555-3750      AC Q0PL14.1
#=GS B1PHJ3_9ALPC/3812-4006      AC B1PHJ3.1
#=GS R1A_CVPPU/3558-3753         AC P0C6V2.1
#=GS A0A125R5A3_9ALPC/3570-3765  AC A0A125R5A3.1
#=GS A0A0U1WHD1_9ALPC/3768-3961  AC A0A0U1WHD1.1
#=GS R1AB_FIPV/3583-3778         AC Q98VG9.2
#=GS R1AB_FIPV/3583-3778         DR PDB; 3UB0 A; 1-192;
#=GS R1AB_FIPV/3583-3778         DR PDB; 3UB0 D; 1-191;
#=GS R1AB_BC279/3926-4122        AC P0C6V9.1
#=GS A3EXE7_BCHK5/4019-4216      AC A3EXE7.1
#=GS R1A_CVHOC/3926-4121         AC P0C6U7.1
#=GS B1PHK1_9ALPC/3775-3968      AC B1PHK1.1
#=GS R1AB_CVM2/3959-4154         AC P0C6X8.1
#=GS H9BZX6_9BETC/4014-4209      AC H9BZX6.1
#=GS A0A0K1RLM9_9ALPC/3554-3749  AC A0A0K1RLM9.1
#=GS R1AB_BCHK4/3973-4170        AC P0C6W3.1
#=GS A0A0U2UMS4_9ALPC/3556-3751  AC A0A0U2UMS4.1
#=GS Q0ZJB1_CVHK1/4013-4208      AC Q0ZJB1.1
#=GS A0A0F6SKM6_9GAMC/3493-3699  AC A0A0F6SKM6.1
#=GS R1A_BCHK4/3973-4170         AC P0C6T4.1
#=GS A0A0K1Z0N1_SARS/3920-4116   AC A0A0K1Z0N1.1
#=GS A0A1X9JQL5_9ALPC/3521-3715  AC A0A1X9JQL5.1
#=GS R1A_BCHK9/3783-3981         AC P0C6T6.1
#=GS A0A1B3Q5W8_9BETC/3825-4023  AC A0A1B3Q5W8.1
#=GS V5TFR4_9GAMC/3449-3641      AC V5TFR4.1
#=GS A0A140ESF0_9NIDO/3189-3356  AC A0A140ESF0.1
#=GS R1A_BCHK5/4020-4217         AC P0C6T5.1
#=GS A0A0U1WHG1_9ALPC/3479-3673  AC A0A0U1WHG1.1
#=GS H9BR16_9NIDO/3154-3335      AC H9BR16.1
#=GS A3EXA2_BCHK4/3973-4170      AC A3EXA2.1
#=GS R1A_BC512/3674-3868         AC P0C6F6.1
#=GS R1AB_CVMJH/4017-4212        AC P0C6Y0.1
#=GS B7U2M9_9BETC/3926-4121      AC B7U2M9.1
#=GS B2BW31_9GAMC/3449-3641      AC B2BW31.1
#=GS C0KYZ6_9BETC/4016-4211      AC C0KYZ6.1
#=GS R1AB_SARS2/3943-4139        AC P0DTD1.1
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BTF D; 84-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6WIQ B; 77-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BV1 D; 85-189;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6M5I B; 82-196;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7C2K D; 53-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BTF B; 67-192;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6XIP D; 78-194;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BV1 B; 78-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BZF B; 79-192;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6M71 D; 84-132;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6XIP B; 78-192;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BW4 B; 78-192;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6YYT B; 6-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6WQD D; 79-192;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BZF D; 84-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6WQD B; 78-197;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BW4 D; 84-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6YYT D; 6-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6M71 B; 78-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7BV2 B; 78-191;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6WTC D; 78-193;
#=GS R1AB_SARS2/3943-4139        DR PDB; 7C2K B; 76-192;
#=GS R1AB_SARS2/3943-4139        DR PDB; 6WTC B; 79-194;
#=GS F2YDB2_SARS/3920-4116       AC F2YDB2.1
#=GS R1AB_CVPPU/3558-3753        AC P0C6Y5.1
#=GS B8Q8U7_SARS/3920-4116       AC B8Q8U7.1
#=GS R9QTB2_SARS/3912-4108       AC R9QTB2.1
#=GS H9BR24_9NIDO/3134-3318      AC H9BR24.1
#=GS R1A_BC279/3926-4122         AC P0C6F5.1
#=GS A0A096XNJ3_9ALPC/3625-3819  AC A0A096XNJ3.2
#=GS R1AB_BCHK9/3783-3981        AC P0C6W5.1
#=GS H9BQZ9_9NIDO/3199-3366      AC H9BQZ9.1
#=GS U5KNA9_9BETC/3992-4189      AC U5KNA9.1
#=GS A0A088DIE1_9BETC/4087-4283  AC A0A088DIE1.1
#=GS A0A0F6WGL5_9GAMC/3493-3699  AC A0A0F6WGL5.1
#=GS A0A240FW17_9ALPC/3214-3406  AC A0A240FW17.1
#=GS R1A_CVMA5/4011-4206         AC P0C6V0.1
#=GS A3EXC0_BCHK4/3983-4180      AC A3EXC0.1
#=GS A0A0P0LKV0_CVH22/3635-3829  AC A0A0P0LKV0.1
#=GS F2YDB1_SARS/3920-4116       AC F2YDB1.1
#=GS T2B9I2_MERS/3929-4126       AC T2B9I2.1
#=GS E0ZN51_BCHK9/3778-3976      AC E0ZN51.1
#=GS S5YAF0_9ALPC/3705-3900      AC S5YAF0.1
#=GS R1AB_CVH22/3630-3824        AC P0C6X1.1
#=GS H9TEW9_9ALPC/3559-3754      AC H9TEW9.1
#=GS A0A0K1YZY7_SARS/3920-4116   AC A0A0K1YZY7.1
#=GS A0A0U1WHG0_SARS/3915-4111   AC A0A0U1WHG0.1
#=GS K4K1U5_9ALPC/3659-3853      AC K4K1U5.1
#=GS T2B9U0_MERS/3929-4126       AC T2B9U0.1
#=GS U5LR11_9BETC/3992-4189      AC U5LR11.1
#=GS A0A0U1WHG4_9ALPC/3621-3815  AC A0A0U1WHG4.1
#=GS A0A0U1UZC3_9ALPC/3534-3728  AC A0A0U1UZC3.1
#=GS H9BZX5_9BETC/4014-4209      AC H9BZX5.1
#=GS A0A023YA54_MERS/4030-4227   AC A0A023YA54.1
#=GS R1A_SARS/3920-4116          AC P0C6U8.1
#=GS R1A_SARS/3920-4116          DR PDB; 6NUR B; 77-191;
#=GS R1A_SARS/3920-4116          DR PDB; 6NUR D; 84-192;
#=GS R1A_SARS/3920-4116          DR PDB; 6NUS B; 80-191;
#=GS A0A0K2RW65_9BETC/3961-4156  AC A0A0K2RW65.1
#=GS B1PHJ4_9ALPC/3812-4006      AC B1PHJ4.1
#=GS A0A0P0ILY9_CVH22/3635-3829  AC A0A0P0ILY9.1
#=GS A0A0A7UXR0_9BETC/3973-4168  AC A0A0A7UXR0.1
#=GS A0A0K2RVJ3_9BETC/3961-4156  AC A0A0K2RVJ3.1
#=GS Q06BE1_9BETC/3926-4121      AC Q06BE1.2
#=GS A8JNZ1_9ALPC/3605-3799      AC A8JNZ1.1
#=GS B2BW32_9GAMC/3449-3641      AC B2BW32.1
#=GS B1PHI7_9ALPC/3868-4062      AC B1PHI7.1
#=GS A8JNZ0_9ALPC/3605-3799      AC A8JNZ0.1
#=GS D9J202_9ALPC/3547-3742      AC D9J202.1
#=GS B6VDX7_THCOV/3168-3337      AC B6VDX7.1
#=GS R1AB_BCHK5/4020-4217        AC P0C6W4.1
#=GS A0A0U1WHK4_SARS/3920-4116   AC A0A0U1WHK4.1
#=GS H9BR34_9NIDO/3092-3261      AC H9BR34.1
#=GS A0A125R5A4_9ALPC/3570-3765  AC A0A125R5A4.1
#=GS E0XIZ2_9BETC/3911-4107      AC E0XIZ2.1
#=GS Q9J3E9_9BETC/4010-4205      AC Q9J3E9.1
#=GS R1A_CVH22/3630-3824         AC P0C6U2.1
#=GS H9TEX0_9ALPC/3559-3754      AC H9TEX0.1
#=GS H9BR07_9NIDO/3177-3344      AC H9BR07.1
#=GS A0A0U1UZA8_9ALPC/3811-4005  AC A0A0U1UZA8.1
#=GS B1PHK0_9ALPC/3775-3968      AC B1PHK0.1
#=GS R1AB_IBVB/3463-3671         AC P0C6Y1.1
#=GS B8Q8S4_SARS/3920-4116       AC B8Q8S4.1
#=GS E0ZN59_BCHK9/3758-3956      AC E0ZN59.1
#=GS H9AA60_9BETC/3947-4142      AC H9AA60.1
#=GS A3EXI9_BCHK9/3778-3976      AC A3EXI9.1
Q6UZF5_SARS/3920-4116                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
A0A0U1UZ20_9ALPC/3775-3968             ...SVASTFVNMPSFIAYETARQNYEDA...TNNGSS.PQLVKQLKRAMNIAKAEFDHEAAVQRKIQRMAEQAASQMYKEARAVNRKSKVISSMHALLFGMLRKLDMSAIDTILNLARGGVVPLNIIPAACATKLVVVASDHESFTRVYQQGAVHYAGAVWTLSEVKDNDGKPVHVKEITKD.....N-TALTWPLVLNCERV---..V--klq...........
B8Q8U6_SARS/3920-4116                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
D9J203_9ALPC/3547-3742                 ...SVASAYASLPSWVAYEQARDAYMEG...KKNDVA.PQVLKQLQKAMNIAKAEFDREASVQKKLDRMAEQAASNMFKEARAVDRKSKIIGAMHSLLFSMLKRLDMSSVNTLIDQARNGCLPLSIIPAASATRLVVVTPNIDVFSKVRLENNVHYAGAVWSIIEVRDSNSSIVHLKEVTQA.....NEQNLCWPLTVTCERVS--..---klqn..........
R1AB_BC512/3674-3868                   ...SVAATYVNLPSYLAYETARQSYEDA...LANGSP.PQLVKQLRHAMNVAKSEFDREASTQRKLDRMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSIIPAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTS.....NVESLAWPLFLNCERI---..---iklq..........
R1A_IBVB/3463-3671                     ...SVTQEFSHIPSYAEYERAKNLYEKVlvdSKNGGVtQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGltyciSGANIAWPLKVNLTRNGHN.kV--dvvl..........
B8Q8S5_SARS/3920-4116                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
R1A_SARS2/3943-4139                    ...AIASEFSSLPSYAAFATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD.....NSPNLAWPLIVTALRANSA..VKL..............
R1A_CVM2/3959-4154                     ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV-.....---NITWPLVIAANRHNEVssVV-l.............
A0A0U1UZ65_BCHK4/3981-4178             atl---TEFSHLATYAELETAQSSYQKA...LNSGDAsPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDVVET.....N-ESLTWPLVIECSRASSS.aVKL..............
R1A_CVMJH/4017-4212                    ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVN.....S----TWPLVISANRHNEVstV--vl............
R1AB_CVHOC/3926-4121                   ...ALQSEFVNMASFVEYEVAKKNLDEA...RFSGSAnQQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDD.....C----NWPLVIIANRYNEV..---satvl.........
B1PHI6_9ALPC/3868-4062                 ...SVASTFVNMPSFMAYENARQSYEEA...INNGSS.PQLVKQLKRAMNIAKAELDHESSVQRKLNRMAEQAAAQMYKEARAVNKKSKVISSLHTLLFGMLRKLDMSSVDNILSLARDGVVPLSIIPAACATKLTIVVSDFESFKRIFQLGNVQYAGVVWSLIEVKDNDGKPVHVKEITAT.....N-TALTWPLILNCERV---..V--klqn..........
R1AB_SARS/3920-4116                    ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
#=GR R1AB_SARS/3920-4116         SS    ...XXGGCSTTSHHHHHHHHHHHHHHHH...HHTTXX.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHT-HHHHHHHHHHHTT-EESS----STT-EEEEEE-SHHHHHHHEETTEEEETTEEEEEEEEE-TTS-B--GGG-STT.....TGGGS-SSEEEEEEEE-XX..XXX..............
A0A059VJE6_9ALPC/3663-3857             ...SVASTYVGLPSYVIYENARQQYEDA...VNNGSP.PQLVKQLRHAMNVAKSEFDREASTQRKLDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSVIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQ.....NAESLSWPLVLGCERI---..---vklq..........
R1AB_CVMA5/4011-4206                   ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVN.....S----TWPLVIAANRHNEVstV--vl............
S5Z1D1_9ALPC/3705-3900                 ...AVATTYANMPSYIMYENARQAYEEA...ISNRSS.PQLIKQLKHAMNRAKGEFDHEAATQRKIDRMAEQAAAQMFKEARAVNKKSKVTSAMHAMLFSMLRRLDMSSVDIILNLARNGTVPLSIIPALCATRLSIIVSDFESYAKLFREGCIHYAGTIWSVADIKNNDGKPVHQKEVTSS.....NAENLSWPLCINAERI---..---vklqn.........
Q0PL14_9ALPC/3555-3750                 ...SVASAYAALPSWIALEKAHADLEEA...KKNDVS.PQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAA.....NELNLTWPLSITCERTT--..---klqn..........
B1PHJ3_9ALPC/3812-4006                 ...SVASTFVNMPSFIAYESARQSYEEA...INNGSS.PQLVKQLKRAMNIAKAELDHESSVQRKLNRMAEQAAAQMYKEARAVNKKSKVISSLHTLLFGMLRKLDMSSVDNILSLARDGVVPLSIIPAACATKLTIVVSDFESFKRIFQLGNVQYAGVVWSLTEVKDNDGKPVHIKEITAN.....N-TALTWPLILNCERI---..---vklqn.........
R1A_CVPPU/3558-3753                    ...SVASAYAALPSWIALEKARADLEEA...KKNDVS.PQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAA.....NELNLTWPLSITCERTT--..---klqn..........
A0A125R5A3_9ALPC/3570-3765             ...SVASAYAALPSWIAYEKARADLEEA...KKNDVS.PQLLKQLTKACNIAKSEFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSIIPAAAATRLIVVTPNLEVLSKIRQENNVHYAGAIWSIVEVKDANGASVHLKEVTAT.....NELNITWPLSLTCERTT--..---klqn..........
A0A0U1WHD1_9ALPC/3768-3961             ...SVASTFVNMPSFIAYETARQNYEDA...TNNGSS.PQLVKQLKRAMNIAKAEFDHEAAVQRKIQRMAEQAASQMYKEARAVNRKSKVISSMHALLFGMLRKLDMSAIDTILNLARGGVVPLNIIPAACATKLVVVASDFESFKRIYQYGAVHYAGAVWTLAEVKDNDGKPVHVKEITND.....N-TALTWPLVLNCERV---..V--klq...........
R1AB_FIPV/3583-3778                    ...SVASAYAALPSWIAYEKARADLEEA...KKNDVS.PQLLKQLTKACNIAKSEFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSIIPAASATRLIVVTPNLEVLSKVRQENNVHYAGAIWSIVEVKDANGAQVHLKEVTAA.....NELNITWPLSITCERTT--..---klqn..........
#=GR R1AB_FIPV/3583-3778         SS    ...SSS-HHHHHHHHHHHHHHHHHHHHH...HHCT--.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHCCHHHH---HHHHHHHHHHHHHHHHHHH--HHHHHHHHHHHTT-EEEEEE--TTS-EEEEEE-SHHHHHHHEETTEEEETTEEEEEEEEE-TTS-B--CCC--GG.....GGGGS-S-EEEEEEE-X--..---XXXX..........
R1AB_BC279/3926-4122                   ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSQNLAWPLIVTALRANSA..VKL..............
A3EXE7_BCHK5/4019-4216                 .at--LSEFSHLASYAELEAAQSSYQKA...LNSGDAsPQVLKALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVLPDITIWNKVVTWPSLSYAGALWDISLINNVDGEVVKSSDVTET.....N-ESLTWPLVLECTRAASS..---avtl..........
R1A_CVHOC/3926-4121                    ...ALQSEFVNMASFVEYEVAKKNLDEA...RFSGSAnQQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDD.....C----NWPLVIIANRYNEV..---satvl.........
B1PHK1_9ALPC/3775-3968                 ...SVASTFVNMPSFIAYETARQNYEDA...TNNGSS.PQLVKQLKRAMNIAKAEFDHEAAVQRKIQRMAEQAASQMYKEARAVNRKSKVISSMHALLFGMLRKLDMSAIDTILNLARGGVVPLNIIPAACATKLVVVASDHESFTRVYQQGAVHYAGAVWTLSEVKDNDGKPVHVKEITKD.....N-TALTWPLVLNCERV---..V--klq...........
R1AB_CVM2/3959-4154                    ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV-.....---NITWPLVIAANRHNEVssVV-l.............
H9BZX6_9BETC/4014-4209                 ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDVN.....S----TWPLVIAANRHNEVstV--vl............
A0A0K1RLM9_9ALPC/3554-3749             ...SVASAYAALPSWIALEKARADLEEA...KKNDVS.PQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQDNNVHYAGAIWTIVEVKDANGSHVHLKEVTAA.....NELNLTWPLSITCERTT--..---klqn..........
R1AB_BCHK4/3973-4170                   atl---TEFSHLATYAELETAQSSYQKA...LNSGDAsPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDVVET.....N-ESLTWPLVIECSRSSSS.aVKL..............
A0A0U2UMS4_9ALPC/3556-3751             ...SVASAYAALPSWIALEKARADLEEA...KKNDVS.PQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAA.....NELNLTWPLSITCERTT--..---klqn..........
Q0ZJB1_CVHK1/4013-4208                 ...ALQSEFVNMASFVEYEVAKKNLADA...KNSGSVnQQQIKQLEKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADGINKQLTDISVD.....S----NWPLVIIANRYNEV..---anavm.........
A0A0F6SKM6_9GAMC/3493-3699             ...SVTQEFSHIPSYAEYERAKDLYEKVladSKNGSVtQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVVPDPETWVKCVEGMLVTYSTVVWNIDTVFDADGVEIQPSSNGQSlvyhiGGDRIAWPLKVNLTRNVHN..---kvea..........
R1A_BCHK4/3973-4170                    atl---TEFSHLATYAELETAQSSYQKA...LNSGDAsPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDVVET.....N-ESLTWPLVIECSRSSSS.aVKL..............
A0A0K1Z0N1_SARS/3920-4116              ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIIQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
A0A1X9JQL5_9ALPC/3521-3715             ...SVASTFASMPSYIAYEKAKMDYEQA...KQNGTS.DQVVRQLLKAMNIAKSEFDLELSVQRKLNRMADNAAAQMFKDARNVDRKAKVVSSMHGLLVAMLRRLDMSSINELMDLAKDGILPLAVIPAAASNRLVVVTPSIEAFDKIRHDNSICYAGSVWTITAIKDVDGTSVQLAEVCAG.....CDGALNWPLHIEAERI---..---vklq..........
R1A_BCHK9/3783-3981                    ...AVASEFSNLSSYVDYENAQKAYDTA...VATGAP.ASTVNALKKAMNVAKSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRE.....NSVNLAWPLVVTAQRQQATspV--kl............
A0A1B3Q5W8_9BETC/3825-4023             ...AVASEFSNLSSYVDYENAQKAYDTA...VTTGAP.VSTIKALKKAMNVAKSVLDKDVATARKLERMSEMAMTAMYKQARAEDKRSKVTSAMQTMLFNMIRRLDSDALNSILTNARNGIVPLGVIPRTAANKLLLVVPDYSVFSSTVVLPTLTYAGSAWDVTQVSDADGKNVNVTDITRE.....NSANLAWPLVITAVRQVA-..---tspvkl........
V5TFR4_9GAMC/3449-3641                 ...AVTDEFCALPSYVDYEKARAAYEEI...QKNSTN.PQEIKAYKKAMNIAKSVLDRDIAVQKKLDAMAERAMSTMYKEAKSSEKKTRLVSSLHALLFSMIKRLDSDQVADVFEKARNGVVPLASVPITCSNKLTIVIPDMSLWEKVVVHDYVVYGNIVWDINEVVDMDGNQILPCRVSGE.....A----SWPLEVRLVRNGKL..---vgd...........
A0A140ESF0_9NIDO/3189-3356             ..a-VADININLDSYRIYKEADAIYKRS...VEMNES.PQXQKKKLKAVNIAKAEWEREAASQRKLEKLADAAMKSMYLAERAEDRRIKLTSGLTAMLYHMLRRLDSDRVKALFECAKAQILPIHAVVGISNDNLKVIFNDKDSYSHYVEGNTLIHKGVRYTIVK-----------------.....-------------------..---klsldnapie....
R1A_BCHK5/4020-4217                    .at--LSEFSHLASYAELEAAQSSYQKA...LNSGDAsPQVLKALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLINNVDGEVVKSSDVTET.....N-ESLTWPLVLECTRAASS..---avtl..........
A0A0U1WHG1_9ALPC/3479-3673             ...SVAATFVNMPSYIAYETARQEYENA...VNTDAS.QSVVKQLRKAMNVAKAEFDKEASVQRKINRMAEAAATQMYKEARAVNKKSKVISSLHAMLFSMLRRLDMSSIDNILSLARDGTVPLSIIPTACATKLTVVCSDIESFSKVVFDNCVQYAGVVWNIIDIRDGDGKIVHLKEVNKD.....NVDVLSWPLFVNCERM---..---vklq..........
H9BR16_9NIDO/3154-3335                 ..v-VADAFIHLDSYKIYKDAQQAYDEA...VERGAE.ASEIKKALKAVNIAKAEYDRDVAAEKKLAKLADSALKSMYLAERSEDRKAKLTSGLTAMLYHMLRRVDSDKVKALFELAKSDVIPLHAITGSSTDGLKVIIGDQQTYEQYVTGNQVIFRGRTYVINTMYDLDNQILQEK-----.....-------------------..---pqsfpivlectk..
A3EXA2_BCHK4/3973-4170                 atl---TEFSHLATYAELETAQSSYQKA...LNSGDAsPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDVVET.....N-ESLTWPLVIECSRSSSS.aVKL..............
R1A_BC512/3674-3868                    ...SVAATYVNLPSYLAYETARQSYEDA...LANGSP.PQLVKQLRHAMNVAKSEFDREASTQRKLDRMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSIIPAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTS.....NVESLAWPLFLNCERI---..---iklq..........
R1AB_CVMJH/4017-4212                   ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVN.....S----TWPLVISANRHNEVstV--vl............
B7U2M9_9BETC/3926-4121                 ...ALQSEFVNMASFVEYEVAKKNLDEA...RSSGSAnQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDD.....C----NWPLVIIANRHNEV..---satvl.........
B2BW31_9GAMC/3449-3641                 ...AVTDEFCALPSYVDYEKARAAYEEI...QKNSTN.PQEIKAYKKAMNIAKSVLDRDIAVQKKLDAMAERAMSTMYKEAKSSEKKTRLVSSLHALLFSMIKRLDSDQVADVFEKARNGVVPLASVPITCSNKLTIVIPDMSLWEKVVVHDYVVYGNIVWDINEVVDMDGNQILPCRVSGE.....A----SWPLEVRLVRNGKL..---vgd...........
C0KYZ6_9BETC/4016-4211                 ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDVN.....S----TWPLVISANRHNEVstV--vl............
R1AB_SARS2/3943-4139                   ...AIASEFSSLPSYAAFATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD.....NSPNLAWPLIVTALRANSA..VKL..............
#=GR R1AB_SARS2/3943-4139        SS    ...XXXXXXTTSHHHHHHHHHHHHHHHH...HHHTXX.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSHHHHHHHHHHHTTEEESSHHHHSTTSEEEEEESSHHHHHHHEETTEEEETTEEEEEEEEEETTSSBE-GGGSSTT.....TGGGS-SSEEEEEEEES-S..XTT..............
F2YDB2_SARS/3920-4116                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
R1AB_CVPPU/3558-3753                   ...SVASAYAALPSWIALEKARADLEEA...KKNDVS.PQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAA.....NELNLTWPLSITCERTT--..---klqn..........
B8Q8U7_SARS/3920-4116                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
R9QTB2_SARS/3912-4108                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
H9BR24_9NIDO/3134-3318                 vvs---DSAIALDSYRVFKDAEAVYLKS...VEDNEP.LAEQKRKLKIANIAKSEWDRDAAANRKLEKLADQAMKAMYLAERSEDRRIKLTSGLTSMLYHMLRRVNSDRIAALFECAKSHVVPIHAIAGSSTEGLKLIIDNQETYNKYVINNGVVYRGTCYNIVKVVDLDNANVTLPP----.....-------------------..---ttypvvvectaair
R1A_BC279/3926-4122                    ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSQNLAWPLIVTALRANSA..VKL..............
A0A096XNJ3_9ALPC/3625-3819             ...SVASTFASMPSYIAYEKAKMDYELA...KQNGTS.DQVVRQLLKAMNIAKSEFDLELSVQRKLNRMADNAAAQMFKDARNVDRKAKVVSSMHGLLVGMLRRLDMSSITELMDLAKDGILPLAVIPAAASNRLIVVTPSIEAFDKIRHDNSICYAGAAWAITAIKDVDGTTVQLAEVCSN.....NDKTLNWPLHIEAERV---..V--klq...........
R1AB_BCHK9/3783-3981                   ...AVASEFSNLSSYVDYENAQKAYDTA...VATGAP.ASTVNALKKAMNVAKSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRE.....NSVNLAWPLVVTAQRQQATspV--kl............
H9BQZ9_9NIDO/3199-3366                 ..a-VADININLDSYRIYKEADAIYKRS...VEMNES.PQEQKKKLKAVNIAKAEWEREAASQRKLEKLADAAMKSMYLAERAEDRRIKLTSGLTAMLYHMLRRLDSDRVKALFECAKQQILPIHAVVGISNDNLKVIFNDKDSYSHYVEGNTLIHKGVRYTIVK-----------------.....-------------------..---klsldnalie....
U5KNA9_9BETC/3992-4189                 stl---TEFSHLASYAELETAQKSYQEA...VASGDAsPQMLKALQKAVNVAKNTYEKDKSIARKLERMAEQAMTSMYKQARAEDKKSKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCVPLSIIPLCASNKLRVVIPDMQIWKQVVTYPVLSYAGALWDITLINNVDGEVVRPSDVIDT.....N-EGLTWPLLLECTRAVAS.aVK-l.............
A0A088DIE1_9BETC/4087-4283             ...AVSNEFNNLPTFVEYECAQKAYDEA...LANGEG.PIVLKQLKKAVNCAKSAFERDAAVARKLERMADLAMTQMYKEARAEDKRARVTSAMQSMLFSMLRRLDNDALNNIITNARDGCVPLNVIPMLASSKLLIVVPDISVYNNTVEGTLLTYAGAVWDVVQVTDADNKPIAMGDITID.....TAPTLAWPLVLSAVRRVSA..TKL..............
A0A0F6WGL5_9GAMC/3493-3699             ...SVTQEFSHIPSYAEYERAKDLYEKVladSKNGSVtQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVVPDPETWVKCVEGMLVTYSTVVWNIDTVFDADGVEIQPSSNGQSlvyhiGGDRIAWPLKVNLTRNVHN..---kvea..........
A0A240FW17_9ALPC/3214-3406             ...SVASTFASLPSFVAYETAREAYEKA...LKEEAN.AVLLKQLKKAMNIAKSEHEQEVAVQRKLERLAETAAAQMYKDVRASDKKAKVISAMHSMLFSMLRRLDMSSVDNVLNLAKDGVVPLSIVPVTSASRMIVVVPTKDVLDRIVTDNSVIYAGVVWTIIDIKDVDNKVINLKEVMIG.....D--DIAYPLHITVERF---..---vklq..........
R1A_CVMA5/4011-4206                    ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVN.....S----TWPLVIAANRHNEVstV--vl............
A3EXC0_BCHK4/3983-4180                 atl---TEFSHLATYAELETAQSSYQKA...LNSGDAsPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDVVET.....N-ESLTWPLVIECSRSSSS.aVKL..............
A0A0P0LKV0_CVH22/3635-3829             ...SVASSFVSMPSFVAYETARQEYENA...VANGSS.PQIIKQLKKAMNVAKAEFDRESSVQKKISRMAEQAAAAMYKEARAVNRKSKVVSAMHRLLFGMLRRLDMSSVDTILNMARNGVVPLSVIPATSASKLVVVVPDYESFAKMLVDGFVHYAGVVWTLQEVKDNDGRNVHLKDVTKE.....NQETLVWPLVLTCERV---..V--klq...........
F2YDB1_SARS/3920-4116                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
T2B9I2_MERS/3929-4126                  .at--LSEFSHLATFAELEAAQKAYQEA...MDSGDTsPQVLKALQKAVNIAKNAYEKDKAVARKLERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVIPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDVVD-.....SNENLTWPLVLECTRASTS.aVKL..............
E0ZN51_BCHK9/3778-3976                 ...AVASEFSNLSSYVDYENAQKAYDTA...VATGAP.ASTVNALKKAMNIAKSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTSANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKPVNATDITRE.....NSVNLAWPLVVTAQRQQATspV--kl............
S5YAF0_9ALPC/3705-3900                 ...AVATTYANMPSYIMYENARQAYEEA...ISNRSS.PQLIKQLKHAMNRAKGEFDHEAATQRKIDRMAEQAAAQMFKEARAVNKKSKVTSAMHAMLFSMLRRLDMSSVDIILNLARNGTVPLSIIPALCATRLSIIVSDFESYAKLFREGCIHYAGTIWSVADIKNNDGKPVHQKEVTSS.....NAENLSWPLCINAERI---..---vklqn.........
R1AB_CVH22/3630-3824                   ...SVASSFVGMPSFVAYETARQEYENA...VANGSS.PQIIKQLKKAMNVAKAEFDRESSVQKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVIPATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKE.....NQEILVWPLILTCERV---..V--klq...........
H9TEW9_9ALPC/3559-3754                 ...SVASAYAALPSWIALEKARADLEEA...KKNDVS.PQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIISAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVVTPSLEVFSRIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAA.....NELNLTWPLSITCERTT--..---klqn..........
A0A0K1YZY7_SARS/3920-4116              ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIIQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
A0A0U1WHG0_SARS/3915-4111              ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVILKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVPLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
K4K1U5_9ALPC/3659-3853                 ...SVASTFVNMPSFIAYENARQAYEDA...IANDSA.PQLVKQLKTAMNIAKSEFDREVSVQKKISRMAEQAAAQMYKEARAVNRKSKVIGAMHSLLMGMLRKLDMSNVDTILNLAKDGVVPLSIIPAACSTKLNVVSADLDSYYKICRDGCVHYAGVIWNVIDIRDNDGKIVHAKEIAPE.....NVENIAWPIFLNCERI---..---vklq..........
T2B9U0_MERS/3929-4126                  .at--LSEFSHLATFAELEAAQKAYQEA...MDSGDTsPQVLKALQKAVNIAKNAYEKDKAVARKLERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVIPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDVVD-.....SNENLTWPLVLECTRASTS.aVKL..............
U5LR11_9BETC/3992-4189                 stl---TEFSHLASYAELETAQKSYQEA...VASGDAsPQMLKALQKAVNVAKNTYEKDKSIARKLERMAEQAMTSMYKQARAEDKKSKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCVPLSIIPLCASNKLRVVIPDMQIWKQVVTYPVLSYAGALWDITLINNVDGEVVRPSDVIDT.....N-EGLTWPLLLECTRAVAS.aVK-l.............
A0A0U1WHG4_9ALPC/3621-3815             ...SVASTFVNMPSFIAYENARQAYEDA...INSGAA.QQLVKQLKRAMNIAKSEFDHEASVQKKISRMAEQAAAQMYKEARAVNRKSKVISAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSIIPAASATKLNVVSADLESYLKICKEGCVHYAGVIWNVIDIRDNDGKLVHMKEVTQE.....NVENLAWPLFLNCERI---..---vklq..........
A0A0U1UZC3_9ALPC/3534-3728             ...SVANTYVNLPSFVAYESARQNYEEA...VNNGSS.PQIIKQMRRAMHLAKAEYDREVSVQRKIERMAENAAAQMYKEARAENRKSKIISSMHALLFGMLRKLDMSSVDTILNLAKNGVVPLSIIPATSATRLCVVCPDHEAYAKIIFGQCLHYAGVVWNIVEVKDNDGKTVHQKEIVKA.....NEETLSWPLSINCERV---..V--klq...........
H9BZX5_9BETC/4014-4209                 ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDVN.....S----TWPLVIAANRHNEVstV--vl............
A0A023YA54_MERS/4030-4227              atl---NEFSHLASFAELEAAQRSYQEA...LDSGDAsPQVLKALQKAVNVAKNAYEKDKSVARKLERMAEQAMTSMYKQARAEDKKSKIVSAMQTMLFGMIKKLDNDVLNGIIANARNGCIPLSIVPLCASNKLRVVIPDFTVWNQVVTYPALNYAGALWDIASINNVDNEIIKSSDVSEN.....N-EHLTWPLVLECTRAAAS.aVKL..............
R1A_SARS/3920-4116                     ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
#=GR R1A_SARS/3920-4116          SS    ...XXXXXXXXXXXXXXXXXXXXXXXXX...XXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHHHHHHHHHHHHHHHHHHHHH-SHHHHHHHHTSSSSEEEGGGSHHHHTSEEEEEESSHHHHHTTEESSEEEETTEEEEEEEEE-TTS-EE-GGG-SST.....TGGGS-SSEEEEEEE-XXX..XXX..............
A0A0K2RW65_9BETC/3961-4156             ...ALQSEFVNMASFVEYEVAKKNLDEA...RSSGSAnQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDD.....C----NWPLVIIANRHNEV..---satvl.........
B1PHJ4_9ALPC/3812-4006                 ...SVASTFVNMPSFIAYESARQSYEEA...INNGSS.PQLVKQLKRAMNIAKAELDHESSVQRKLNRMAEQAAAQMYKEARAVNKKSKVISSLHTLLFGMLRKLDMSSVDNILSLARDGVVPLSIIPAACATKLTIVVSDFESFKRIFQLGNVQYAGVVWSLTEVKDNDGKPVHIKEITAN.....N-TALTWPLILNCERI---..---vklqn.........
A0A0P0ILY9_CVH22/3635-3829             ...SVASSFVSMPSFVAYETARQEYENA...VANGSS.PQIIKQLKKAMNVAKAEFDRESSVQKKISRMAEQAAAAMYKEARAVNRKSKVVSAMHRLLFGMLRRLDMSSVDTILNMARNGVVPLSVIPATSASKLVVVVPDYESFAKMLVDGFVHYAGVVWTLQEVKDNDGRNVHLKDVTKE.....NQETLVWPLVLTCERV---..V--klq...........
A0A0A7UXR0_9BETC/3973-4168             ...ALQSEFVNMASFVEYEIAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSAIPSLTANSLTIIVPDKTVYDQVVDNVYIAYAGNVWHIQSIQDADGTVKQLNEINES.....----VNWPIVVTATRYNEV..---sttvm.........
A0A0K2RVJ3_9BETC/3961-4156             ...ALQSEFVNMASFVEYEVAKKNLDEA...RSSGSAnQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDD.....C----NWPLVIIANRHNEV..---satvl.........
Q06BE1_9BETC/3926-4121                 ...ALQSEFVNMASFVEYEVAKKNLDEA...RSSGSAnQQQLKQLEKACNIAKSAYERDLAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDD.....C----NWPLVIIANRHNEV..---satvl.........
A8JNZ1_9ALPC/3605-3799                 ...SVASAFANMPSFIAYEKARMNYEDA...IANDAA.PAVVKQLKKAMNTAKGEFDHEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDMSSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYAGAAWSITDVQDADGRVTILKEINAD.....NKDALVWPLHVTCERV---..V--klq...........
B2BW32_9GAMC/3449-3641                 ...AVTDEFCALPSYVDYEKARAAYEEI...QKNSTN.PQEIKAYKKAMNIAKSVLDRDIAVQKKLDAMAERAMSTMYKEAKSSEKKTRLVSSLHALLFSMIKRLDSDQVADVFEKARNGVVPLASVPITCSNKLTIVIPDMSLWEKVVVHDYVVYGNIVWDINEVVDMDGNQILPCRVSGE.....A----SWPLEVRLVRNGKL..---vgd...........
B1PHI7_9ALPC/3868-4062                 ...SVASTFVNMPSFMAYENARQSYEEA...INNGSS.PQLVKQLKRAMNIAKAELDHESSVQRKLNRMAEQAAAQMYKEARAVNKKSKVISSLHTLLFGMLRKLDMSSVDNILSLARDGVVPLSIIPAACATKLTIVVSDFESFKRIFQLGNVQYAGVVWSLIEVKDNDGKPVHVKEITAT.....N-TALTWPLILNCERV---..V--klqn..........
A8JNZ0_9ALPC/3605-3799                 ...SVASAFANMPSFIAYEKARMNYEDA...IANDAA.PAVVKQLKKAMNTAKGEFDHEASVQKKIQRMADAAAAQMYKDARAVDRKSKVVSAMHSLLFGMLRKLDMSSINQLMELAKDGCIPMAIIPAAAATKLTVITPDLESFSKIRVDNNIYYAGAAWSITDVQDADGRVTILKEINAD.....NKDALVWPLHVTCERV---..V--klq...........
D9J202_9ALPC/3547-3742                 ...SVASAYASLPSWVAYEQARDAYMEG...KKNDVA.PQVLKQLQKAMNIAKAEFDREASVQKKLDRMAEQAASNMFKEARAVDRKSKIIGAMHSLLFSMLKRLDMSSVNTLIDQARNGCLPLSIIPAASATRLVVVTPNIDVFSKVRLENNVHYAGAVWSIIEVRDSNSSIVHLKEVTQA.....NEQNLCWPLTVTCERVS--..---klqn..........
B6VDX7_THCOV/3168-3337                 ..a-VVDANINLDSYRIYKEADAIYKKS...VDMDEP.LQIQKKKLKAVNIAKAEWEREAASQRKLEKLADAAMKSMYLAERAEDRRIKLTSGLTAMLYHMLRRLDSDRVKALFECAKQQILPIHAIVGVSNDNLKVIFNDKDSYIQYVDGNTLFYKGQRYTIVK-----------------.....-------------------..---klsldnapiegt..
R1AB_BCHK5/4020-4217                   .at--LSEFSHLASYAELEAAQSSYQKA...LNSGDAsPQVLKALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLINNVDGEVVKSSDVTET.....N-ESLTWPLVLECTRAASS..---avtl..........
A0A0U1WHK4_SARS/3920-4116              ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
H9BR34_9NIDO/3092-3261                 ..a-VVDANIHMDSYRIFKEAEQAYKKS...VELNEP.IQEQKKKLKAVNIAKSEWERDAASQKKLEKLADAAMKSMYLAERAEDRRIKLTSGLTAMLYHMLRRIDSDKVKALFECAKQSILPIHAVVGVSSDALKVIFNDKESYMQYITGNILIYKGVSYNILKVTSLDN-----------.....-------------------..---spiegi........
A0A125R5A4_9ALPC/3570-3765             ...SVASAYAALPSWIAYEKARADLEEA...KKNDVS.PQLLKQLTKACNIAKSEFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSIIPAAAATRLIVVTPNLEVLSKIRQENNVHYAGAIWSIVEVKDANGASVHLKEVTAT.....NELNITWPLSLTCERTT--..---klqn..........
E0XIZ2_9BETC/3911-4107                 ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYNTYKNTCDGNTFTYASALWEIQQVVDADSKVVQLSEINMD.....NSQNLAWPLIVTALRSNSA..VKL..............
Q9J3E9_9BETC/4010-4205                 ...ALQSEFVNMASFVEYELAKKNLDEA...KASGSAnQQQIKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVN.....S----TWPLVIAANRHNEVstV--vl............
R1A_CVH22/3630-3824                    ...SVASSFVGMPSFVAYETARQEYENA...VANGSS.PQIIKQLKKAMNVAKAEFDRESSVQKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVIPATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKE.....NQEILVWPLILTCERV---..V--klq...........
H9TEX0_9ALPC/3559-3754                 ...SVASAYAALPSWIALEKARADLEEA...KKNDVS.PQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIISAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVVTPSLEVFSRIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAA.....NELNLTWPLSITCERTT--..---klqn..........
H9BR07_9NIDO/3177-3344                 ...AVADANVNLDSYRIYKEADAAYKRS...VEMNES.PQEQKKKLKAVNIAKAEWERDAASQRKLEKLADAAMKSMYLAERAEDRRVKLTSGLTAMLYHMLRRLDSDRVKALFECAKQQILPIHAIVGISNDNFKVIFNDKDSYLQYVDGNTLIYKGVRYTIVK-----------------.....-------------------..---klsldnapie....
A0A0U1UZA8_9ALPC/3811-4005             ...SVASTFVNMPSFIAYESARQSYEEA...INNGSS.PQLVKQLKRAMNIAKAELDHESSVQRKLNRMAEQAAAQMYKEARAVNKKSKVISSLHTLLFGMLRKLDMSSVDNILSLARDGVVPLSIIPAACATKLTIVVSDFESFKRIFQLGNVQYAGVVWSLTEVKDNDGKPVHIKEITAN.....N-TALTWPLVLNCERI---..---vklqn.........
B1PHK0_9ALPC/3775-3968                 ...SVASTFVNMPSFIAYETARQNYEDA...TNNGSS.PQLVKQLKRAMNIAKAEFDHEAAVQRKIQRMAEQAASQMYKEARAVNRKSKVISSMHALLFGMLRKLDMSAIDTILNLARGGVVPLNIIPAACATKLVVVASDHESFTRVYQQGAVHYAGAVWTLSEVKDNDGKPVHVKEITKD.....N-TALTWPLVLNCERV---..V--klq...........
R1AB_IBVB/3463-3671                    ...SVTQEFSHIPSYAEYERAKNLYEKVlvdSKNGGVtQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGltyciSGANIAWPLKVNLTRNGHN.kV--dvvl..........
B8Q8S4_SARS/3920-4116                  ...AIASEFSSLPSYAAYATAQEAYEQA...VANGDS.EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD.....NSPNLAWPLIVTALRANSA..VKL..............
E0ZN59_BCHK9/3758-3956                 ...AVASEFSNLSSYVDYENAQKAYDTA...VSTGAP.ESTVKALKKAMNVAKSVLDKDIATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVPDYSVFTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRE.....NSANLAWPLVVTAQRQL--..---atspvkl.......
H9AA60_9BETC/3947-4142                 ...ALQSEFVNMASFVEYEVAKKNLDEA...RSSGSAnQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPLLTANTLTIIVPDKQVFDQVVDNVYVAYAGNVWHIQSVQDADGTNKQLNEISED.....S----NWPLVIVANRHNEV..---sqavl.........
A3EXI9_BCHK9/3778-3976                 ...AVASEFSNLSSYVDYENAQKAYDTA...VATGAP.ASTVKALKKAMNVAKSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRE.....NSVNLAWPLVVTAQRQQATspV--kl............
#=GC SS_cons                           ...SSCGCCTTSHHHHHHHHHHHHHHHH...HHCTXX.HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSHHHHHHHHHHHTTEEESSCCHHSTTSEEEEEESSHHHHHHHEETTEEEETTEEEEEEEEEETTSSBE-GGGSSTT.....TGGGS-SSEEEEEEEESXS..XTT..............
#=GC seq_cons                          ...ulASpFsslsSastYEsAcpsY-cA...hssGsu..QllKpLcKAhNlAKSpa-RDsAVQRKL-RMA-pAhosMYKpARupD+KoKVlSAMpoMLFuMLRKLDssulNsIlspARsGsVPLslIPhssAs+LhVVlPDhpsasplsstsslsYAGslWsIpplpDsDGp.VplsElsts.....N..sLsWPLllsspRts.......hh............
//
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