#=GF ID CpgS_C
#=GF AC PF29746.1
#=GF DE Cyclic 2,3-diphosphoglycerate synthetase C-terminal domain
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE TED:Q1AVG0_TED03
#=GF GA 27.00 27.00;
#=GF TC 40.60 88.60;
#=GF NC 25.80 21.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch --cpu 8 -E 1000 -Z 90746521 HMM pfamseq
#=GF TP Domain
#=GF DR SO; 0000417; polypeptide_domain;
#=GF CC This entry represents the C-terminal domain of cyclic
#=GF CC 2,3-diphosphoglycerate synthetase (cDPGS, EC 6.5.1.9). The
#=GF CC full-length enzyme catalyses the formation of cyclic
#=GF CC 2,3-diphosphoglycerate by formation of an intramolecular
#=GF CC phosphoanhydride bond. The function of this domain remains to be
#=GF CC determined.
#=GF SQ 43
#=GS CPGS_THEGJ/320-408 AC C5A4R5.1
#=GS A0A166E948_9EURY/339-430 AC A0A166E948.1
#=GS A0A0U2L4X1_9EURY/338-429 AC A0A0U2L4X1.1
#=GS A0A328S2C1_9EURY/338-429 AC A0A328S2C1.1
#=GS A0A540WAJ8_9ACTN/341-430 AC A0A540WAJ8.1
#=GS A0A8J7X7P5_9EURY/328-420 AC A0A8J7X7P5.1
#=GS A0A1Q6DSD4_METT1/355-446 AC A0A1Q6DSD4.1
#=GS CPGS_METKA/337-428 AC Q8TY02.1
#=GS A0A1V1RG67_9ACTN/326-417 AC A0A1V1RG67.1
#=GS A0A023X335_RUBRA/326-416 AC A0A023X335.1
#=GS A0A1D3L1X8_9EURY/339-430 AC A0A1D3L1X8.1
#=GS A0A5D0MDR6_9BACT/351-442 AC A0A5D0MDR6.1
#=GS U6EDM6_9EURY/339-430 AC U6EDM6.1
#=GS A0A6G8QA90_9ACTN/320-410 AC A0A6G8QA90.1
#=GS A0AA43ZVZ6_9EURY/341-432 AC A0AA43ZVZ6.1
#=GS CPGS_METTH/341-432 AC O26325.1
#=GS A0A166CR67_9EURY/339-430 AC A0A166CR67.1
#=GS A0A942JWY2_9FIRM/327-418 AC A0A942JWY2.1
#=GS A0A7M2YY08_9ACTN/307-396 AC A0A7M2YY08.1
#=GS A0A7J9WHM3_9ACTN/366-456 AC A0A7J9WHM3.1
#=GS A0A1V6N2Z8_METAZ/339-430 AC A0A1V6N2Z8.1
#=GS R9SKC5_9EURY/336-427 AC R9SKC5.1
#=GS A0A2U1S8I4_9EURY/344-435 AC A0A2U1S8I4.1
#=GS CPGS_THEKO/319-407 AC Q5JDW8.1
#=GS A0A166FD03_9EURY/339-430 AC A0A166FD03.1
#=GS A0A328SCL7_9EURY/337-428 AC A0A328SCL7.1
#=GS CPGS_PYRFU/318-405 AC Q8U4K6.1
#=GS A0A328SHD9_9EURY/341-432 AC A0A328SHD9.1
#=GS A0A328P8M7_9EURY/339-430 AC A0A328P8M7.1
#=GS CPGS_METFV/339-430 AC O93732.1
#=GS CPGS_METST/341-432 AC Q2NHT6.1
#=GS A0A1D2RCE0_9ARCH/336-427 AC A0A1D2RCE0.1
#=GS A0A8T8K822_9EURY/339-430 AC A0A8T8K822.1
#=GS A0A366MDN7_9EURY/339-430 AC A0A366MDN7.1
#=GS A0A4V2NX06_9ACTN/325-415 AC A0A4V2NX06.1
#=GS CPGS_THESM/319-409 AC C6A0T3.1
#=GS A0A126QZ55_METOL/339-430 AC A0A126QZ55.1
#=GS A0A328S7K6_9EURY/107-198 AC A0A328S7K6.1
#=GS A0A6I4MQ00_9ACTN/334-426 AC A0A6I4MQ00.1
#=GS CPGS_RUBXD/325-415 AC Q1AVG0.1
#=GS F0T7P1_METLA/339-430 AC F0T7P1.1
#=GS A0A6G8PWW8_9ACTN/1-74 AC A0A6G8PWW8.1
#=GS A0A942QJ99_9ACTN/327-418 AC A0A942QJ99.1
CPGS_THEGJ/320-408 .PLGDVSGKRIGLVMTS-EEALES.SARHLEA-LGAEVLHSSGNLSRRKALLRDLEGFSGI.-EGIAVELKAAAVDVVTRWALERGIEVIYLDNE.
A0A166E948_9EURY/339-430 .PLGDIKNKKVLFATTAPEAIKSV.LVSHLEKKYGCTVVGTTPHLSNRPLLQKDIAKYIDN.VDVMLTELKAAAVDVATKDSLEAGLEVVYCDNI.
A0A0U2L4X1_9EURY/338-429 .PLEDISGKKVLFATTAPEEVKDK.LVDYLEEKYSCEVVGTTSHLSNRPLLKEDMEKYMDK.ADVMLTELKAAAVDVATKDAINAGLEVVYCDNI.
A0A328S2C1_9EURY/338-429 .PVDNIENKNILFATTAPESVQHL.LKEYLEDNFNCNVVAISSNLSNRPLLQEDIDNNIDK.VDIMLTELKAAAVDVATKDALTKGLEVVYCDNI.
A0A540WAJ8_9ACTN/341-430 .PVSDVSGRRVAFFTTAAPHLLPG.MIDHLRTRYGTCVVHATGALADRNRLQAELAEVD--.ADVYLVELKAAAIDVVAEHAEQRGIPVVFCDT-e
A0A8J7X7P5_9EURY/328-420 .PLADVSDRKIFLATTAPPAILEStLVPYLEQNYHCDIVKASPHLSNRPRLRKDLEQFLPQ.VDTLLTEIKASAIDVATREALALHRDVVFMDN-v
A0A1Q6DSD4_METT1/355-446 .PLDEVARRDVFVATTASDQSNKS.IKAYLEEEYGCRVKEISNNLSNRIKLKKDLNRSISS.CDILLTEIKAASIDVAAKKAKKEGLEIVFLHNR.
CPGS_METKA/337-428 .PTEDVEGKRAMFVTTAPEEVVSR.LVEHLEEEYGCEIVGTSPHLSNRPKLRKDLEKYIDD.ADILLTELKAAAVDVATREALKAGLGVVYVDN-v
A0A1V1RG67_9ACTN/326-417 .PLEPIEGARVFFASTAPEALLER.LGRHLEAAYGCEVVATSPDLSNRAKLRDAIAAVAGK.VDVYVTELKAAAIDVVAALGEEMGVRTVLADN-v
A0A023X335_RUBRA/326-416 .PVESVEGAKVAYVSTAPEAVLKK.LAGYLEESFGCEVVGTSGNLSNRVRLEEDLRKLREA.-EVYLTEIKAAAVDVVTARGAEEGKRVVYCDND.
A0A1D3L1X8_9EURY/339-430 .PLGNINNKNVLFATTAPDSIKDV.LIEHLEDNYGCKVVGTTPYLSNRPLLQKDIEKYIDE.ADVMLTELKAAAVDVATKDALKAGLEVVYCDNI.
A0A5D0MDR6_9BACT/351-442 .PLGNIRKKKVFVATTAPGKIRDK.ILNYLEKQYSCEVVGYSKHLSNREKLRKDLDKNLDE.CDILLTEIKAASIDVAAKKAEKMDVDIIFMHNE.
U6EDM6_9EURY/339-430 .PLESVEGKRVLFATTAPDSVKEV.LIKHLEEEHGCTVVGTTPYLSNRPLLQKDIERYIDQ.VDVMLTELKAAAVDVATKDALQAGLEVVYCDNI.
A0A6G8QA90_9ACTN/320-410 .PVGDVSGLRLAYVSTAPESVLNK.LARHLETRYGCEVAAASGNLSDRRRLAADLDGMPPV.-DAYLTEIKAAAIDVITRRGAEEGRPVLYCDND.
A0AA43ZVZ6_9EURY/341-432 .PLESIENKRVLFTTTAPESMKGV.LKKYLEEEYNCIIVDISTNLSDRPLLEEDIERNIND.IDLMLTEVKAAAIDVATKLALDKNLKVVYCDNI.
CPGS_METTH/341-432 .PLGEIEGKNVLFATTAPDSVKDL.LVEYLESEYSCRVVGTTPHLSNRPLLQRDIERYIED.ADVMLTELKAAAVDVATKDALEAGLEVIYCDNI.
A0A166CR67_9EURY/339-430 .PLGDITGKSVLFATTAPKTIQKV.LVEHIESEYNCKVIGTTPHLSNRPLLQKDLDKYIGE.ADVMLTELKAAAVDVATKDALKYGLEVIYCDNI.
A0A942JWY2_9FIRM/327-418 .PIEPVDGARVFFATTAPAEALGL.MTAHLEAEYGCTVVGASASLSNRSLLRREMAACAGR.YDVLLTELKAAAIDVVAAVGEEVGVPTVLCDN-v
A0A7M2YY08_9ACTN/307-396 .PTTSIVGRTIAYFGTAPATQHER.IARHLSDGHGAVVAHVSGSLCDRGALRRELARVD--.ADTFVVELKAAAVDVVVEEASRRGVDVVLTGN-d
A0A7J9WHM3_9ACTN/366-456 .PLDQVSGERVFFATTAPAAVGAS.LVEALEDTYGCDVVATSSRLADRPGLRSDLYAAPAF.-DVLLVELKAAAVDVATRIAAQAGARVVFCDNR.
A0A1V6N2Z8_METAZ/339-430 .PHGDINGKNVLFATTAPDEVKDV.LVSHLEENYGCKVVGTTPHLSNRPLLQKDIEKYIDH.VDVMLTELKAAAVDVATKDSLEAGLEVVYCDNI.
R9SKC5_9EURY/336-427 .PLKSIKGKKVLFATTAPNAVKDK.LVEYLEGVYECEIIGTTPYLSNRPLLKKDIGKYIND.VDCMLTELKAAAVDVATKEAINAGLEVVYCDNI.
A0A2U1S8I4_9EURY/344-435 .PLGDIAGKKVLFATTAPEAVQDK.LVEYLELNYDCKIVGITSHLSNRPLLKKDIEEHMDE.ADVMLTELKAAAVDVATKDSIDAGLEVVYCDNI.
CPGS_THEKO/319-407 .PLGNISGKKLGLVMTS-QSALPK.AKEHLEG-LGAEVVATSGNLSNRPKLREDLEKFRGI.-DAVAVELKAAAVDVVTKWALERGIEVIYLDNE.
A0A166FD03_9EURY/339-430 .PLGDISGKNVLFATTAPDGIKEV.LVNHLQDNYNCNVVGITSHLSNRPLLQEDINKYIDK.ADVMLTELKAAAVDVATKDSLDAGLEVVYCDNI.
A0A328SCL7_9EURY/337-428 .PVEDITGRNILFATTAPETVQPL.LKKYLEENFNCNVVDISSNLSNRPLLQEDIERNIDN.IDTMLTELKAAAVDVATKDALERQLEVVYCDNI.
CPGS_PYRFU/318-405 l-IGEVDGKAI-IATTNPQSA-KK.FSEELEK-MGIEVVYYTGNLAKRNILKDELAKVNYD.-DTAIVELKAGAVDVVIRHAFSRGKRVVFLDNE.
A0A328SHD9_9EURY/341-432 .PVESIENKRVLFATTAPENVQPL.LKSYLEDNFKCTVVDISSHLSNRPLLQEDIERNIDN.VDVMLTEIKAAAIDVATKDALDRNLEVVYCDNI.
A0A328P8M7_9EURY/339-430 .PLQDIKDKNVLFATTAPESIMDV.LVAYLEDKYKCNIVGTTTHLSNRPLLQKDIEKYINE.AEVMLTELKAAAVDVATKDALDAGLDVVYSDNI.
CPGS_METFV/339-430 .PVGNVEGKKVLFATTAPKVVVGK.LVNYLESKYGCDVVGVTPHLSNRPLLRRDLKKYINK.ADLMLTELKAAAVDVATRVAIEAGLDVVYCDNI.
CPGS_METST/341-432 .PVDDISNKNILFATTAPESVQHL.LKDYLEENFNCNVVAISSHLSNRPLLQRDIEENIDN.IDCMLTELKAAAVDVATKDALNKGLEVVYCDNI.
A0A1D2RCE0_9ARCH/336-427 .PLGNINGKKVLFATTAPEGVLHK.LVSFLEEEFDCKVIGSTHHLSDQAKLKKDIDKYIDK.ADVVLTELKAAAVKVVTKEAVSAGIDVVYCDNI.
A0A8T8K822_9EURY/339-430 .PLGDIQNKNVLFATTAPDSVKKV.LVDHLESEYGCKVIGTTPHLSNRPLLQKDIQKYIDE.VDVMLTELKAAAVDVATKDALEAGLEVVYCDNI.
A0A366MDN7_9EURY/339-430 .PLGDISGKNVLFATTAPDEIKDV.LVNHLEENHDCKVVGTTPHLSNRPLLQADIEKYINH.ADVMLTELKAAAVDVATKDSLEAGLEVVYCDNI.
A0A4V2NX06_9ACTN/325-415 .PAESVEGLRVAYVSTAPGSMLEK.LAGYLEREFGCEVAAVSGNLSNRRLLAQDLEAVGE-.VDAYLTEIKAAAVDVVTRRAAERGVGVVYCDNE.
CPGS_THESM/319-409 .PLSEIKGKKAILVMTAPPEGLEK.AARHLENRYDVEIVGKSANLANRPKLIEDLSRFKYY.-DTVLVELKAAAVDVATKEALKYGKEVIYIDNE.
A0A126QZ55_METOL/339-430 .PLGDISGKKVLFVTTAPDSVRDV.LSNYLEETYDCKVVGLSSHLSNRPLLKEDIDKYKDD.VDCIVTELKAAAVDVVTNEAIELGIELIYCDNI.
A0A328S7K6_9EURY/107-198 .PLNNIENKNVLFATTAPDSVKDV.LIDYLEENYNCNIVGVTPHLSNRPLLQADIEKYIDE.VDLILTELKAAAVDVVTKDSLEAGLDVVYCDNI.
A0A6I4MQ00_9ACTN/334-426 .PLDGVAGKRVWFATTADPRYGPV.LRQHLEDAHGAEVTGLSHALADRDRLRVDLDTQAARgAEVLAVELKAAAVDVVTQCATERDVEVVYVENR.
CPGS_RUBXD/325-415 .PVGEVRGMRVAYVSTAPPAVLKR.LAGHLEEGYGCEVVAVSGNLSNRSKLAEDLEGMPGV.-DAYLTEIKAAAVDVVTRRGAEEGRRVIYCDND.
F0T7P1_METLA/339-430 .PLGDVKGKNVLFATTAPDSIKSV.LIEHLEDFYGCKVVGTTPYLSNRPLLQKDIEKYIDE.ADVMLTELKAAAVDVATKDALKAGLEVIYCDNI.
A0A6G8PWW8_9ACTN/1-74 m--------------------LPK.LAGHLEERYGCEVVASSGNLSDRKALARDLDAARDLpFDAYLTEIKAAAIDVVTRRGAEEGRPVLYCDND.
A0A942QJ99_9ACTN/327-418 .PIESVEGARVFFATTAPPEVLPN.LVAHLESVHGCEVVGFSPHLSNRTLLRQDMRAAEGR.YDLLLTELKAAAIDVVAAVGEETGVRTVLCDN-v
#=GC seq_cons .PLsslpGK+VhFATTAP-slhch.LspaLEcpYuCcVVusospLSNRPlLpcDl-+hhsp.sDlhLTELKAAAVDVAT+cAlctGl-VVYCDNh.
//
