#=GF ID DUF16
#=GF AC PF01519.19
#=GF DE Protein of unknown function DUF16
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Pfam-B_764 (release 4.0)
#=GF GA 30.40 30.40;
#=GF TC 30.40 30.90;
#=GF NC 30.30 30.30;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Coiled-coil
#=GF WK Domain_of_unknown_function
#=GF RN [1]
#=GF RM 8948633
#=GF RT Complete sequence analysis of the genome of the bacterium
#=GF RT Mycoplasma pneumoniae.
#=GF RA Himmelreich R, Hilbert H, Plagens H, Pirkl E, Li BC, Herrmann R;
#=GF RL Nucleic Acids Res 1996;24:4420-4449.
#=GF RN [2]
#=GF RM 16522803
#=GF RT Crystal structure of the DUF16 domain of MPN010 from Mycoplasma
#=GF RT pneumoniae.
#=GF RA Shin DH, Kim JS, Yokota H, Kim R, Kim SH;
#=GF RL Protein Sci. 2006;15:921-928.
#=GF DR INTERPRO; IPR002862;
#=GF DR SO; 0001080; coiled_coil;
#=GF CC The function of this protein is unknown. It appears to only
#=GF CC occur in Mycoplasma pneumoniae. The crystal structure revealed
#=GF CC that this domain is composed of two separated homotrimeric
#=GF CC coiled-coils [2].
#=GF SQ 36
#=GS Y501_MYCPN/39-113 AC P75286.1
#=GS Y524_MYCPN/40-125 AC P75254.1
#=GS A0A1M6CJZ4_9CLOT/2-77 AC A0A1M6CJZ4.1
#=GS Y410_MYCPN/39-146 AC P75374.1
#=GS Y287_MYCPN/2-116 AC P75490.1
#=GS Y100_MYCPN/110-181 AC P75592.1
#=GS Y655_MYCPN/97-195 AC P75136.1
#=GS A0A0Q5TCD4_9BACT/2-121 AC A0A0Q5TCD4.1
#=GS Y010_MYCPN/37-130 AC P75103.1
#=GS Y010_MYCPN/37-130 DR PDB; 2BA2 C; 205-285;
#=GS Y010_MYCPN/37-130 DR PDB; 2BA2 A; 5-85;
#=GS Y010_MYCPN/37-130 DR PDB; 2BA2 B; 106-185;
#=GS Y484_MYCPN/2-102 AC P75301.1
#=GS Y504_MYCPN/39-125 AC P75282.1
#=GS A0A559KC87_9BACL/17-100 AC A0A559KC87.1
#=GS Y137_MYCPN/43-170 AC P75261.1
#=GS Y104_MYCPN/3-103 AC P75565.1
#=GS Y130_MYCPN/39-139 AC P75345.1
#=GS Y013_MYCPN/179-256 AC P75100.1
#=GS R9MH93_9FIRM/34-128 AC R9MH93.1
#=GS A0A4Z0R8R3_9FIRM/8-75 AC A0A4Z0R8R3.1
#=GS Y138_MYCPN/39-157 AC P75260.1
#=GS Y344_MYCPN/86-194 AC P75434.1
#=GS Y100_MYCPN/39-114 AC P75592.1
#=GS A0A4R1QQV7_9FIRM/119-190 AC A0A4R1QQV7.1
#=GS A0A5M6CFR4_9BACT/3-80 AC A0A5M6CFR4.1
#=GS Y139_MYCPN/39-154 AC P75259.1
#=GS Y204_MYCPN/39-146 AC P75572.1
#=GS Y151_MYCPN/2-110 AC P75035.1
#=GS Y094_MYCPN/39-139 AC P75598.1
#=GS Y368_MYCPN/39-157 AC P75413.1
#=GS Y501_MYCPN/110-167 AC P75286.1
#=GS Y127_MYCPN/77-166 AC P75348.1
#=GS Y038_MYCPN/29-115 AC P75076.1
#=GS Y013_MYCPN/108-216 AC P75100.1
#=GS Y283_MYCPN/40-115 AC P75494.1
#=GS Y145_MYCPN/37-164 AC P75141.1
#=GS A0A4R2RZD1_9FIRM/82-156 AC A0A4R2RZD1.1
#=GS A0A4Z0R8R3_9FIRM/66-155 AC A0A4Z0R8R3.1
Y501_MYCPN/39-113 ..........................................EFSG..KFNRQFKLnkpvIPVNTEYVTRKEFNE....YKNS..........NDQRLTKIETTLA..................AQGEQINKLTQTVEKQGEQINQLVQ----------..............-------------------------vv..........................
Y524_MYCPN/40-125 ...................................elrkykl----..------KP....-PVKVKYVTQEQFQE....YKDS..........NNQRLIKIETTLA..................AQGEQI-------RIQVEQIKELQIEQKAQGE---..............----TLKLILQTLQKMSDRLDKME-v...........................
A0A1M6CJZ4_9CLOT/2-77 .......................................tdq----..--------....---------------....---D..........LQHTLNQIVGMID..................TLGKKIDRLEEKVDRIEERLDRIEERLDRVEERLD..............RVEERLDRVEERLDRVEARLDSLE-............................
Y410_MYCPN/39-146 ..........................................EFSG..SFNRQFKLnkpiIPVNTEYVTRKEFNE....YKDS..........NDQRLIKIETTLT..................AQGEQINKLTQTVEKQGEQIRELQVEQKAQGEQIK..............AQGETLKLILQTLQKMSDRLDKID-p...........................
Y287_MYCPN/2-116 .........................................g-FSD..NLNHMEKR....---KSGYVTQKQFSE....FKDA..........NNQRLIKIETTLA..................TQGEQLNQLIKVVILQGEQIKELQVEQKAQGEQIKakgeqikaqseqikTQGETLKLILQALGGINKRLDKVD-p...........................
Y100_MYCPN/110-181 .......................................vqv----..--------....---------------....----..........-----------VL..................LHGEQINKLTQTVEKQGEQIKELQVEQKAQGEQIKaqg.......kqikAQGKTLKSILQALGGINKRLDKID-p...........................
Y655_MYCPN/97-195 .......................................qpg---GpdNPNAGNKK....MPTPEEYVTRKEFNE....FKDS..........NNQRLTKIENKVD..................KLEVKVDKLAEIVQTQGEEIKELKVEQKAQSE---..............----TLQLILKTLQKMNDRLDRMET............................
A0A0Q5TCD4_9BACT/2-121 yieeridlaeislvehgkqiemiatglatlttlvytgfaemr----..--------....---------------....----..........--EEFVQVHKRID..................NLEIRFNKLEDKVDRLEIRIDRLEVRLDKVEARLD..............KVEERLDKIEERLDKIEERLDKIE-arldnles....................
Y010_MYCPN/37-130 .........................................w-LKG..VFEEIVKT....-P-GTRYVTHKQLDE...kLKNF.........vTKTEFKEFQTVVM..................---ESFAVQNQNIDAQGEQIKELQVEQKAQGK---..............----TLQLILEALQGINKRLDNLES............................
#=GR Y010_MYCPN/37-130 SS .........................................X-XXX..XXXXXXXX....-X-XTTB-BHHHHHH...HHTTB.........-BHHHHHHHHHHHH..................---HHHHHHHHHHHHHHHHHHHHHHHHHHHHH---..............----HHHHHHHHHHHHHHHHHHHC-............................
Y484_MYCPN/2-102 .........................................g-FYG..NLNHMEKR....---KSGYVTQKQFND....FKNS..........NNQRLIKIENTLV..................SQGEQISQLIKVSILQGEQINKLTETVEKQGEQIQ..............TQGETLKLILETLQVINKRLDRLES............................
Y504_MYCPN/39-125 ..................................yelrkykl----..------KP....-PVKVKYVTQEQFQE....YKDS..........NNQRLIKIENKVD..................-------KLVEIVQIHGEQI-------KAQGE---..............----TLQLILQTLQKMSDRLDKME-kridkles....................
A0A559KC87_9BACL/17-100 .......................................lsh----..--------....-----------DLSE....FRIE..........VDQRFAGLEHRMD..................RLEERMVKLEARMDRLEERMVKLEARMDRLKERME..............KLEERMNKLEERMSKLEERMDRL--ge..........................
Y137_MYCPN/43-170 .........................................s-FNG..DFEVVTKK....-P-STKYVTHKQLDQklkeFKQDlmvelhdtfaTKADLRDSEARINqklea.......lvqvvlLHGEQINKLTQIVEKQGEQIRELQVEQKAQRQEFN.............aRMDRLENLLVESIESTNKRFDSIEG............................
Y104_MYCPN/3-103 ....................................eldgkf----..--------....---------------....---A..........TKADLKRVEDKVDvlfelqk....tqgeqikVQGKQIEQLTETVQKQGEQIKELQVQVKAQGEEIKeik.......veqkAQGQTLQLILKALEGINKRLDNLES............................
Y130_MYCPN/39-139 ..........................................EFSG..NFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLIKIETTLA..................AQGEQ-------IRIQGEQIKELQIEQKAQSE---..............----TLKLILQTLQKMSDRLDKMD-vrldkles....................
Y013_MYCPN/179-256 ........................................kq----..--------....---------------....----..........----IEQLTETVK..................VQGEQIRAQGEQIKAQSEEIKEIKVEQKAQGEQIKelq.......veqkAQGKTLQLILKTLEKMNERLEKLES............................
R9MH93_9FIRM/34-128 ..................................leekldak----..--------....------------LQF....YMEK..........TNQRFDKLENKVE..................KVGQRLDSLEEKVEKVEQRLDSLEEKVEKVEQRLDsle.......ekveKVEQRLDSLEEKVEKVEQRLDSLE-e...........................
A0A4Z0R8R3_9FIRM/8-75 .................................ekilqaieg----..--------....---------------....LKND..........MDHKFDKLSEKVD..................NQGSQIDKLSEKVDNQGSQIDKLSEKVDNQGSQID..............KLSEK--------------------vd..........................
Y138_MYCPN/39-157 ..........................................EFSG..NFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIENKVD..................KLEVKVDKLEEKVDKLEAKVDKLEEKVDKLEAKVDkleek...vdkleaKVDSGFEMLAKILAAINKRLDSIEG............................
Y344_MYCPN/86-194 ....................................qpggpd----..DPNSGNKK....MPKPDEFVTHRQLQE....FKKDllvelheifpTKPELKRVEEKVD..................VLFELQKAQGEQIRIQGEQIKELKVEQKAQGE---..............----TLQLILQTLQKMNDRLDKIEG............................
Y100_MYCPN/39-114 ..........................................EFSG..SFNRQFKLnkpvIPVNTEYVTRKEFNE....YKVS..........NDQRLTKIETTLA..................AQGEQINKLTQTVEKQGEQINQLVQ----------..............-------------------------vvl.........................
A0A4R1QQV7_9FIRM/119-190 ......................................evkv----..--------....---------------....----..........-----DSLEAKVG..................SLETKVDSLETKVDSLETKVNSLETKVDSLEVKTN..............GLIEDMDIIKPSLVKMSNRLDNIEG............................
A0A5M6CFR4_9BACT/3-80 ......................................kvcr----..--------....------------FKE....WVNR..........LKGRVNRLEERVN..................KLEERVNRLEERVNKLEERVNRLEERVNRLEERMN..............RLKERVNGLEERVNK----------lrpp........................
Y139_MYCPN/39-154 ..........................................EFSG..SFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIETELK..................SQGQRIQVVEDKVDRLTEVVMVQSQQIKTQGEAMNarmd......rfesLVLKSLESIGNTLTDFGKRLDVIET............................
Y204_MYCPN/39-146 ..........................................EFSG..KFNRQFKLnkpvITVNTEYVTRKELNE....YKDS..........NDQRLTKIETTLA..................AQGEQINKLTQTVEKQGEQIRELQVEQKAQGEQIK..............AQGETLKLILQTLQKMSDRLDKID-p...........................
Y151_MYCPN/2-110 ..........................................EFNG..NLNHMEKR....---KSGYVTQKQFNE....YKDS..........NDQRLIKIETTLA..................AQGEQISQLVQIVFLQGKQIKELQAEQKAQRVEFNarmd......rfesLVLKSLESIGNTLTDFGKRFDSMET............................
Y094_MYCPN/39-139 ..........................................EFSG..NFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIETTLA..................AQGEQ-------IRIQGEQIKELQIEQKAQGETLK..............LILQTLQKMSDRLNKMDVRLDKLE-s...........................
Y368_MYCPN/39-157 ..........................................EFSG..SFNRQFKLnkpvIPVNTEYVTRKEFNE....YKDS..........NDQRLTKIENKVD..................KLEIKVDKLEKKVDKLEVKVDKLVETVNAQGEDLNnfkve...vrgtlqSQGETLQLILQTLQGMSKRLDSVEG............................
Y501_MYCPN/110-167 .......................................vqv----..--------....---------------....----..........-----------VL..................LHGEQINKLTQTVEKQGEQIKELQIEQKAQGE---..............----TLKLILQTLQKMSDRLDKME-v...........................
Y127_MYCPN/77-166 .........................................g-FNG..NFNHMEKR....---KSGYVTQKQFSE....FKDA..........NNQRLIKIETTLA..................IQGEQINKLTQTVEKQGEQINQLVQVVLLQGA---..............-------------------------sklenfkwskkhkdksl...........
Y038_MYCPN/29-115 .........................................g-FHG..NLNHMEKG....---KSGYVTHKQLDKklevFKQ-..........---DL-----LVE..................-LSEKF-VTKEEFRAQGKQIKELQIEQKAQGK---..............----TLQLILEALQGINKRLDKLES............................
Y013_MYCPN/108-216 ..................................pggpddps----..---EGKQK....VSKPDKYVTHRELDE...kLK-Df........aTKADFKRVEDKVDvlf...........elqkTQGEQIKVQGEQIKAQGKQIEQLTETVKVQGEQIR..............AQGEQIKAQSEEIKEI---------kveq........................
Y283_MYCPN/40-115 ...................................elrkykl----..------KP....-PVKVKYVTQEEFGE....FKDA..........TNQRLTKIENALV..................AQGEQIRAQGEQLSQLIKVVLLQGEQIKSQGEQIK..............-------------------------s...........................
Y145_MYCPN/37-164 .........................................s-LNG..VFEEIVKT....-PGKTRYVTHKQLDQklkdFKQDlmvelhdtfaTKTDLKESEARINqklealiqivmvqgeqikVHGEQINKLTQAVEKQGEKI-------EAQGQQIQ..............KVNETLNFVVESLGSIHKRLDSMEG............................
A0A4R2RZD1_9FIRM/82-156 .......................................dkv----..--------....---------------....----..........-EERLSKVEGRLD..................KVEERLNKMDERFDKVEERLDKMDERFDKVEERLD..............KMDERFDKVEEQFDKMDERFDQMDG............................
A0A4Z0R8R3_9FIRM/66-155 ........................................qi----..--------....---------------....----..........-----DKLSEKVD..................NQGSQIDKLSEKVDNQGSQIDKLSEKVDHQGSQIK..............ENTQILKAL-EHLAQVNK-------aehdkmsfniaeisgeikairkdlsnve
#=GC SS_cons .........................................X-XXX..XXXXXXXX....-X-XTTB-BHHHHHH...HHTTB.........-BHHHHHHHHHHHH..................---HHHHHHHHHHHHHHHHHHHHHHHHHHHHH---..............----HHHHHHHHHHHHHHHHHHHC-............................
#=GC seq_cons ......................................................K.........stYVTpcphp-....aKps..........spp+Lp+lEspls..................spGEplspLpppVcpQGEQIccLp.c.csQGEphp..............h..psLphlhppLpphscRLDph-.............................
//
