GenomeNet

Database: Pfam
Entry: DUF2118
LinkDB: DUF2118
Original site: DUF2118 
#=GF ID   DUF2118
#=GF AC   PF09891.11
#=GF DE   Uncharacterized protein conserved in archaea (DUF2118)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4072)
#=GF GA   20.50 20.50;
#=GF TC   20.50 20.50;
#=GF NC   20.40 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0105
#=GF DR   INTERPRO; IPR019217;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain, found in various hypothetical archaeal proteins,
#=GF CC   has no known function.
#=GF SQ   23
#=GS B8D6F0_DESA1/4-152        AC B8D6F0.1
#=GS Q9YB32_AERPE/20-168       AC Q9YB32.1
#=GS A0A075LQD5_9EURY/2-163    AC A0A075LQD5.1
#=GS A0A5C8Z3C1_9GAMM/248-310  AC A0A5C8Z3C1.1
#=GS A0A0U3EEE1_9CREN/4-149    AC A0A0U3EEE1.1
#=GS A2BK90_HYPBU/13-160       AC A2BK90.1
#=GS D7DV81_METV3/5-160        AC D7DV81.1
#=GS F6BEB9_METIK/1-152        AC F6BEB9.1
#=GS A3DMR4_STAMF/4-160        AC A3DMR4.1
#=GS C6A019_THESM/2-163        AC C6A019.1
#=GS Q8TXA2_METKA/1-162        AC Q8TXA2.1
#=GS A8ABP2_IGNH4/4-149        AC A8ABP2.1
#=GS Q6M171_METMP/1-150        AC Q6M171.1
#=GS Q6M171_METMP/1-150        DR PDB; 3D4R D; 1-150;
#=GS Q6M171_METMP/1-150        DR PDB; 3D4R B; 1-150;
#=GS Q6M171_METMP/1-150        DR PDB; 3D4R E; 1-150;
#=GS Q6M171_METMP/1-150        DR PDB; 3D4R A; 1-150;
#=GS Q6M171_METMP/1-150        DR PDB; 3D4R F; 1-150;
#=GS Q6M171_METMP/1-150        DR PDB; 3D4R C; 1-150;
#=GS A0A2R4ZU92_9CREN/9-160    AC A0A2R4ZU92.1
#=GS A0A0V8RTM4_PYROC/12-160   AC A0A0V8RTM4.1
#=GS Q8U1K5_PYRFU/2-163        AC Q8U1K5.1
#=GS G0EE93_PYRF1/11-160       AC G0EE93.1
#=GS D5U3E6_THEAM/4-158        AC D5U3E6.1
#=GS Q5JEN4_THEKO/2-163        AC Q5JEN4.1
#=GS Y859_METJA/4-156          AC Q58269.1
#=GS R7PSJ1_9FIRM/21-94        AC R7PSJ1.1
#=GS I0A0D6_FERFK/6-145        AC I0A0D6.1
#=GS E0SQA2_IGNAA/15-153       AC E0SQA2.1
B8D6F0_DESA1/4-152                   ...................................................................................YSFPQLFVEDVDSE...............--RIICLKNSEYAwAGI..PEK......N.NC..TKYY...GSIPY.EE-ILKYID.LEKAIL.K.RSTILFNT...gEPSKALFFSENT.QLCLQEAKG.RRVFYIGSM-KHVRKNDLIAYIVTGKNEV.RNIYSTCEGFI..LAVIDLTW...ERPERIIVVVA--ie........................
Q9YB32_AERPE/20-168                  ...................................................................................YRFPELYLEGYVSE...............---RAIWVDEEEG.KYY..RRP......V.EG..LKRY...GLAVY.EHAIKEAID.LVGSRV.S.RGFVVVIP...wKGMRGLMLREGT.RVKLVEAAG.VQVSHYSLEGTRVGERSVLSYVLTGKGET.RTLRAGVEGVV..AIILTDHN...RQPPAYIYVIADE..........................
A0A075LQD5_9EURY/2-163               ..................................................................................e-KMPMLFVEKSYDEcfeeekakneciiiqDNIEVKLSKGDKL.PNF..IDK......N.KA..KFLT...-KEVY.DR-FHLYVD.KNEMKM.L.RDAIIVLP....GRRTQIKLKKGD.KLMILPVEG.FVSTLIAGVGNRVRKSDAFAAVTTKKGEV.HYLKPPKSGVV..VYIDEFTN...--RPHYLYYLLPE..........................
A0A5C8Z3C1_9GAMM/248-310             ...............................................................................dsgi--------------...............-------------.---..---......-.--..----...-----.---------.------.-.--------....------------.---------.--VSHIVQLGDRVRAGDLLAVIRSPMGEVlDEVRASREGIV..IGKQNIPL...TH-----------egeamyhvaf................
A0A0U3EEE1_9CREN/4-149               ...................................................................................YEFPKLFVEGIDGE...............----EYLEITDNS.AKI..SKE......P.SS..PK-L...GKVPL.EIDLEEIVD.LLGERV.K.RSFAVYNP....RKKVVIYVREGT.PIKILRVDH.KKVLIELSEGDEINLDSTYAHGITSKGEY.RRFRSKVKGIV..VLVHWKPL...GGRDIYHVIVAE-r.........................
A2BK90_HYPBU/13-160                  ...................................................................................YHIPRIYIEGIGSD...............----EYLELVDST.ARR..TDR......C.SG..RRCF...GKAIY.GTLLDEIAD.LLAKKA.T.RSFIVVLP...pDYRKGLLVEAGS.YLEPVPLEG.MRVVIHVCEGDRVEEGSTLGFIATRKFEV.RHIRSHVEGVV..VYIYSSPE...GPPDRNIVFIAPE..........................
D7DV81_METV3/5-160                   ...................................................................................MKIPKLYVENNIFEd.............nEPCEKIAVSEKEI.IFLdsDEV......V.DN..YKNT...HKILY.KVRYDDIRS.YIDNDVlK.KDIFVKYP....GNHTFTHIKAGT.YITCVLADS.KTTYPILDAGSVVLRDGILATLKSNKGVI.RYLKSPVSGTV..FFMNEIFE...GNNSIYLFAIVE-n.........................
F6BEB9_METIK/1-152                   ...................................................................................MKIPRLYVEGETEK..............nEGRKVVIENDGKV.IRF..LDE......D.EE..YEGE...GKVLY.QVIYDDFDKyILLSKL.T.RDVLIQYP....DKRTITYLKKGT.ELLEIPAEG.YEVHPIVDFGCRVLEGHRLAALVTKKGEI.RFVNTPVTGTV..VFMKEVPA...-KRANYVFYILPE..........................
A3DMR4_STAMF/4-160                   ...................................................................................YRYPEVFVEGVESD...............---KYVLEINEHY.ILV..LTKedlekyV.NY..KRVF...GHIIY.EH-IINYID.LVKPAT.K.KAFIVIPEysgeKEMNGFLIDENK.KLCLIEVKG.IQPYVFPREGDEIEERDKVAYIITGKGEV.RTIRSPCKGVV..LLVINFPW...EKPEKYVLAVV--nk........................
C6A019_THESM/2-163                   ...................................................................................EKIPQLFVESNLEEcvdgekarvdcriiqDNIEVKVKKGEKI.PEF..IDP......K.RA..KFMK...-KEVY.DR-FHFYVD.KYEHKM.M.CNAIIILP....DRRTEIRLYKGD.ELMLLPVEG.YVSSIIAGVGNRVRKSDAFAAITTKKGEV.HYLKPPKTGVV..VYIDEFTN...--RPHYVYYILPE..........................
Q8TXA2_METKA/1-162                   ...................................................................................MALPRIYVETDEVPesgk......illtdPEFEVIVRSRELA.EKI..AEE......L.DE..PIFY...EQVVY.EE-ARSVFD.VPEAKV.T.RHVVIEPV....DRRSLVFLKPGD.RVYQIPVEG.YVVTPIADVGDRLRKGDPLAAVTTRSGNV.RYVEAPQDCLV..VYVCEQPAirtQRRPNYEYYIAPT..........................
A8ABP2_IGNH4/4-149                   ...................................................................................YKFPRLFVEGKEGE...............---EYAVVEGDEV.VFV..KEK......V.PG..AL--...GKVPY.EIPLDEIVD.KLKEEA.K.VTFLIHLP....NEDKAILVPKGS.KVKLFKVSH.VKVGVTVKEGDELEEGDTYAYGLTGKGEV.RRFRSIVKGKV..VMVHWEPY...GGRDDYHVLVVPE..........................
Q6M171_METMP/1-150                   ...................................................................................MKIPKIYVEGELND...............-GDRVAIEKDGNA.IIF..LEK......D.EE..YSGN...GKLLY.QVIYDDLAKyMSLDTL.K.KDVLIQYP....DKHTFTYLKAGT.KLISVPAEG.YKVYPIMDFGFRVLKGYRLATLESKKGDL.RYVNSPVSGTV..IFMNEIPS...-ERANYVFYMLEE..........................
#=GR Q6M171_METMP/1-150        SS    ...................................................................................SE--EEEEET--SS...............-S-EEEEEGGGTE.EEE..E-T......T.--..--SS...SEEEE.EESSS-GGGGEETTEE.S.S-EEEEET....TSSEEEEE-TT-.B-EEEEEES.SEEEESS-TSEEE-TT-EEEEEE-TTS-E.EEEE-SSSEEE..EEEEEETT...-CEEEEEEEEEE-..........................
A0A2R4ZU92_9CREN/9-160               ................................................................fpyiavssrcvedpdrygk--------------...............---RYCVEDPGEN.PVV..TAG......C.SSncSDCY...VEVPY.EEAEQLI--.MGSGVI.K.CGFIIMWE....GSDQCLLVREGV.AAHNIEIEG.YRVYGIVSEGESVTKGDRIAYIVTGKGEV.RTVRSSFAGVV..AYAAQKPE...SKPEKLLLII---ig........................
A0A0V8RTM4_PYROC/12-160              ..................................................................................y-LIPQLFIEGLESS...............---DYLVLRNGVA.QRS..RGC......P.EG..ERCF...GKAIY.GVELESIVD.LVAKKS.R.RSFIVVLP...rEYRRGLLVEAGS.PVEPIPLEG.MRVVLEVCEGSRVGVQSTLGFIATRKLEV.RRIRSHVKGVV..VYIYSSPE...AGPDKNIVLVAPE..........................
Q8U1K5_PYRFU/2-163                   ..................................................................................s-RTPQLYVEVPKEEclegrrvkhdciviqDNIEVRLREGEEV.PEF..IQV......D.KA..KFLA...-KEIY.DR-FHFYVD.HYEHRM.K.VDAIIVYP....DRRTKIYLKKGD.ELLLLPVEG.YVVTLIADVGNRVRKGDAFAAVTTRKGEV.HYLKPPKPGTV..VYIDEFTN...--RPHYIYYILPE..........................
G0EE93_PYRF1/11-160                  ..................................................................................y-LIPRLYIEGIKGD...............---EYLVESGEGV.YKR..SKS......CpSG..SRCY...GKAIY.GVELDSILD.LLEKKV.K.RSFIVEPG...dKPGEGILVESGV.HAEPIPVSG.KRAVIEVLEGDEVKEGDVLGLIVTGKYEL.RKVRSHVDGIV..VYIYSSPM...GPPDENIVFIVP-r.........................
D5U3E6_THEAM/4-158                   ..................................................................................y-FFPEAYVENGLES...............-GRSICFKGNDIY.IAF..AKN......A.GT..GECVktfVNTPF.EK-LVEYMD.LEKPCF.T.RDVIIVHRe.egGYYKGFLIEKGE.KLYLLEASG.STIAVSKREGDAVEPHEKIGYIITNKREV.RVIKAPLKGIL..LAVIDLTW...EKPEKIIM-----vftge.....................
Q5JEN4_THEKO/2-163                   ...................................................................................EKLPKLYVETTQEEcvkdgktlaecvvimGNVEVWLKENEEL.PDF..IDP......S.RA..KFLK...-REVY.DR-FYLYVD.RTEQKM.T.ADVILVLP....DGRTRIYLKKGD.ELMILPVEG.FTKTLIANVGNRVRTGDAFAAVTTRKGEV.HYLKPPKTGTV..VFIDEITN...--RPHYLYYILPE..........................
Y859_METJA/4-156                     ...................................................................................MRIPRLYVENAEKH...............EGRKVVIENGGKV.IKF..LDK......D.EE..YEGD...GKVLY.QVIYDDFDNyVLMGTV.T.KDMIIEYEv..gGVRQITYIKKGT.KLLEIPAEG.YKVYPIVDFGCRILGGHRIAALQSRKGDI.RFVNTPVNGIV..LFLKEVPA...-KRENYVFYILPE..........................
R7PSJ1_9FIRM/21-94                   ......................................................................gesfafvpqmsvl--------------...............-------------.---..---......-.--..----...-----.---------.------.-.--------....------------.-------SG.KTVSVIA-EGTRVKEGDVLVLVDSLVGPV.PAARATVDGVV..IEVT----...-------------vgngqiidqndqvavi..........
I0A0D6_FERFK/6-145                   ................................................................................yrl--------EDDKKI...............PSVKNYLKSNENI.ESK..LDI......S.LD..RIAC...EEIIF.NN--ISFGE.RNICVS.K.GNFIIKTP....KN--SFLIERNE.ELKYFIIEA.SQINTRKKPGDSVKKWDEIAVSKSKKGIL.RRIKIPFEGQI..ILVEQDPT...-YKPERIVFIL--k.........................
E0SQA2_IGNAA/15-153                  ..............................................................vsynsklyvdlekkifcdkpm--------------...............-------------.---..---......A.DD..NRVF...VEIVY.EKLPEIAID.FENNIL.R.IDVAIYIP....SKDIVLFIKRGS.NVDILEAQG.KIIIPLVNSGESVESNTKVFYRITKKYET.RTHRAETVGLV..VYIGEMFI...-------------gdsekmiavtvge.............
#=GC SS_cons                         ...................................................................................SE--EEEEET--SS...............-S-EEEEEGGGTE.EEE..E-T......T.--..--SS...SEEEE.EESSS-GGGGEETTEE.S.S-EEEEET....TSSEEEEE-TT-.B-EEEEEES.SEEEESS-TSEEE-TT-EEEEEE-TTS-E.EEEE-SSSEEE..EEEEEETT...-CEEEEEEEEEE-..........................
#=GC seq_cons                        ....................................................................................phPplaVEs..pc..................chhlcps-ph..th..hct......s.ps..tphh...s+hlY.ch.hcphhD.hhtpph.p.+shllhhP....ctcptlhlccGs.clh.l.s-G.hpVshlss.Gs+Vccu-tlAhlhTpKGEV.Rhl+usspGlV..lalpphst....t.sphlhhlh............................
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