GenomeNet

Database: Pfam
Entry: DUF2175
LinkDB: DUF2175
Original site: DUF2175 
#=GF ID   DUF2175
#=GF AC   PF09943.12
#=GF DE   Uncharacterized protein conserved in archaea (DUF2175)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4847)
#=GF GA   25.10 25.10;
#=GF TC   25.10 28.70;
#=GF NC   25.00 25.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR018686;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This domain, found in various hypothetical archaeal proteins,
#=GF CC   has no known function.
#=GF SQ   30
#=GS A0A2K5AP70_9ARCH/3-99   AC A0A2K5AP70.1
#=GS T0LEJ2_9ARCH/2-99       AC T0LEJ2.1
#=GS A0A218ZTR3_9ARCH/2-100  AC A0A218ZTR3.1
#=GS A8MAU7_CALMQ/2-101      AC A8MAU7.1
#=GS A0A2U9IFL8_9CREN/6-105  AC A0A2U9IFL8.1
#=GS Q4J6F1_SULAC/6-105      AC Q4J6F1.1
#=GS A0A0Q0XG23_9ARCH/1-98   AC A0A0Q0XG23.1
#=GS Q8ZW53_PYRAE/5-102      AC Q8ZW53.1
#=GS A0A550D458_9CREN/6-104  AC A0A550D458.1
#=GS T0LZY7_9ARCH/2-99       AC T0LZY7.1
#=GS A0A2R4ZNA2_9CREN/1-89   AC A0A2R4ZNA2.1
#=GS G0ED30_PYRF1/3-100      AC G0ED30.1
#=GS W7KYI0_9CREN/1-84       AC W7KYI0.1
#=GS A0A510DWB1_9CREN/6-104  AC A0A510DWB1.1
#=GS S0ATM0_FERAC/1-98       AC S0ATM0.1
#=GS E1QS86_VULDI/4-103      AC E1QS86.1
#=GS G4RLB9_THETK/2-99       AC G4RLB9.1
#=GS A0A2T9X6N3_9CREN/6-106  AC A0A2T9X6N3.1
#=GS A0A348B0V9_9CREN/6-105  AC A0A348B0V9.1
#=GS A0A2H5VD43_9ARCH/3-99   AC A0A2H5VD43.1
#=GS C5BJX0_TERTT/24-103     AC C5BJX0.1
#=GS T0NBF4_9ARCH/2-93       AC T0NBF4.1
#=GS Q96YF7_SULTO/6-106      AC Q96YF7.1
#=GS Q9YG14_AERPE/4-100      AC Q9YG14.2
#=GS A0A031LQF1_9CREN/6-105  AC A0A031LQF1.1
#=GS Q6L0P6_PICTO/1-98       AC Q6L0P6.1
#=GS A4YHY1_METS5/8-107      AC A4YHY1.1
#=GS A0A2T9WWK5_9CREN/1-85   AC A0A2T9WWK5.1
#=GS H2C9I3_9CREN/6-105      AC H2C9I3.1
#=GS F4BA85_ACIHW/7-106      AC F4BA85.1
A0A2K5AP70_9ARCH/3-99              ...t-RWSCAICSRQIAWSELFTFY.SKGAVHFTCFKETTISKD.KSD..EVKVLLDALEHELKMIVAYKGYITMV..KN-DD.AKRLLEENEKDAEKHAALLTKLID-r........
T0LEJ2_9ARCH/2-99                  ...a-EFKCYICSEKAATGEKFTFT.SNGAVHYDCFIAHKRKEL.GN-..QNAELLSELAVILDAELTHLLALLRV.eVHTED.GKKHLQTKYKEIEKAAGETTKLIN-g........
A0A218ZTR3_9ARCH/2-100             ...a-EFICYSCKKLVITGEKFTFT.AKGAVHFDCFVSEKRKSI.SE-..DKVQKLRILSSVLESELDHLLNLLSArsGESEE.YKEEMRIKYKDIEKAAGETTSLISK.........
A8MAU7_CALMQ/2-101                 ...a-EWKCMVCGGNVVDGQLFTFI.KGGPIHWSCLVKAINDKF.NGKvpSDVLAILTINRHIHEGIVLAKESEQV..ISDDS.VKQVISSRRKLLEGEAAKLNVDML-k........
A0A2U9IFL8_9CREN/6-105             ....TKWNCDICKNPIYWDELFTFTsKKAVVHYTCFRDKALKTS.KIDenQLKSILDSLEDELKMITVYKQRISGL..SN-EE.AKKYMEQAEKDAEKNASLLTRLAE-k........
Q4J6F1_SULAC/6-105                 ....TKWNCGLCGKPIYWDELFTFMsNKAVVHYTCFKEKASSTS.KVDkdVMKVILDSLEDELNKIVVYKQRLSKV..ND-EE.IKKVLDQTEKDAEKNAALFTRLVEK.........
A0A0Q0XG23_9ARCH/1-98              ...m-EYNCYLCNKTIKTGEKFTFT.KEGSVHLDCFISNKRKSL.DE-..GRLEYLRTLSLILDYELTYLIQLLSL.rTDDKE.SQELVRKRITAIEKESGETTNLIY-n........
Q8ZW53_PYRAE/5-102                 ....KKWKCAVCGEEIIEGQVFTFY.SKGPVHWECLERELSGKV.YKD..ADLAALLRLDHFLHEGIVLAKELEYL..AQGEV.AKERIREIRKQLEVLAAKLTNEIT-s........
A0A550D458_9CREN/6-104             ....TKWKCALCNNTIYWDELFTYM.KKGVVHYTCLRDLALKNS.KIDnkELQNILDALEEELKLIVYYKQKISSL..QN-EE.IKKTFDQIEKDAEKNAGILTRLVEK.........
T0LZY7_9ARCH/2-99                  ...a-QFKCYECSKDVNTGQKFTFT.KKGSVHYDCFVSSKRKTI.DP-..EKAEMLRTLSLILDSELTHLLNLLRI.sPEDEA.SKEIEKSKYKEIEKAAGETTRRID-e........
A0A2R4ZNA2_9CREN/1-89              ...m------------IEGQRFLVIkNIGFAHLECVVEELVKKHpNIS..RDALSLIEANEAITYAIVRLKTAELQ..AQSDT.QRSMISAARKDLEKHSAFLGNEL--gk.......
G0ED30_PYRF1/3-100                 ...r-KWRCVICGDEIIEGQRFTVL.RDGFVHLECLFEKLVKEG.RLS..QDIAALMDAVEVLNYLIVRIKEAKRL..ASSRE.VIDMLEAVRIDAEKHAAQISSLLE-r........
W7KYI0_9CREN/1-84                  ....----------------MFTFTsKKTVVHYTCFKDKAMKTA.KVDesQMKAVLDSLEDELRLITVYKQRMSVV..NN-EE.AKKYMEQAEKDAEKNAAMFTRAVEK.........
A0A510DWB1_9CREN/6-104             ....TKWACAFCGNTIYWDELFTFM.KSGVVHYTCFRDRAIKTS.KVPpeEMKVVLDMLEKELLRITEYKKTMSSI..AN-EE.IKKSLDQIEKDAEKQSGVLTRL---asn......
S0ATM0_FERAC/1-98                  ...m-EYGCYTCNKIIKTGEKFTFT.KEGPVHLDCFVATQRKKV.PE-..EKQEYLRNLSMVLDYELTYLVELLGL..KSDDKpTSEFIKRRITAIEKQAGETTGLI--yn.......
E1QS86_VULDI/4-103                 ...k-IWKCYRCGEEVVEGMKFTFT.KQGPIHWECFRAEVRDRF.NGSipEDVNIMLELLDYLADGIVKIKELETR..ASSDE.LRQVLMARRKIIEGEMAKLMSELNK.........
G4RLB9_THETK/2-99                  ....KKWVCYVCGKDIVEGQMFTFT.NKGPVHQACLQRAIAPKL.YQS..ATDAALFELLSLANEGIVKIKSLEEL..IADEE.AKRLAAEFRKSLEGFAARLTNKLV-e........
A0A2T9X6N3_9CREN/6-106             ....TKWSCGLCGNPIYWDELFTFLsNKAVVHFTCLKEKALKTA.RVSqdTMNIVLDSLQDELNKIVVYKQRMSKA..GDNEE.VKKALEQTEKDAEKNSAILTRLVEK.........
A0A348B0V9_9CREN/6-105             ....TKWKCGFCENQIAWEEPFTYMsNKTVVHFTCLKDRALRTP.KGDqeTLRAVLDSLEEELTSIQNYKARLSKI..TN-DE.VRKVLDQAEKDAEKNAGILTRMIEK.........
A0A2H5VD43_9ARCH/3-99              ....TKWSCAICSRQIAWSELFTFY.SKGAVHFTCFKETTISKD.KSD..EVKVLLDALEHELKMIVAYKGYITMV..KN-DD.AKRLLEENEKDAEKHAALLTKLID-r........
C5BJX0_TERTT/24-103                ..ms--LKCIFCKKPVFGGNGMTVP.KQGPAHLVCFQADQALRR.TFQ.hLDISALNDEELRELKELVLAEENFRS..RD---.-------------------------eesrssdie
T0NBF4_9ARCH/2-93                  yapg----------PVKTGEKFTFT.RDGSVHFDCFVSKRRQEV.SP-..EKQEDLRILANILDSELQHLLNILAL.qNTPES.VKEKVRVKYKDVEKAAGETTRMIS-e........
Q96YF7_SULTO/6-106                 ....TKWTCGFCGKPIYWDELFTFLsNKAVVHYTCLRERATKTS.KINpeVLKVVLDSLEDELNKIVIYKQRLNQV..GDNED.IKKVLDQTEKDAEKNAAQLTRLVEK.........
Q9YG14_AERPE/4-100                 ....KTWECSICGGTIIEGQRFTFIpGQGAVHFECLAESTLKKP.SG-..-DAVALLDANEVLLYTIVRLKEAARI..AESEE.IKNSIDNVRIEVERLAGILSKKLV-e........
A0A031LQF1_9CREN/6-105             ....TKWKCDLCNNAIYWDELFTYTsKKNVVHFNCFKDKALKTT.KIDekQIRAIVDSLEDELKMITLYKQRIPLV..TD-EE.VKKFMEQAEKDAEKNSAMLTRAVEK.........
Q6L0P6_PICTO/1-98                  ...m-EYKCYICKKAFRSGEKFTFT.KEGSVHLDCFVSDKRLKI.EE-..NKIEKLRTLSLILDYELTYLVELLNI.kPEDDE.SKEITRQKIKELEKASGETTKMIY-e........
A4YHY1_METS5/8-107                 ....TKWTCDICKNKIYWDELFTFTsKKAVVHYTCFRDKASKTA.KIEpaQLEIVLDMLEDELRDITIYKQKINVV..KE-EE.IKKVLEQAEKDAEKNSALLTRVVEK.........
A0A2T9WWK5_9CREN/1-85              ...m----------------RFTFT.RNGAIHWECFRLNVSEAF.KGSipEDVNVLMELMDYLNEGIVRLRELEMR..ALSDG.VREGIINRRKILEGEAARVMKDLE-s........
H2C9I3_9CREN/6-105                 ....TKWTCDLCKSKIYWDELFTFTsKKTVVHYTCFRDKATKTA.KLEpnQMKIILDSLEDELTDITVYKQRMSSN..LE-ED.VKKTLEQAEKDAEKNAALLTRLVEK.........
F4BA85_ACIHW/7-106                 ....TKWTCDICKNTIYWDELFTFTsKKTVVHYTCFREKALKTA.KVDqeQLTAILDSLEDELKMIVVYKQRLGKI..KD-EE.VKKYMEQAEKDAEKNSAMLTRAVEK.........
#=GC seq_cons                      .....cWpChlCsptIhhsEhFTFh.+cGsVHasCFpccthKps.chs..phtshLcsLpc.Lphhllahpclppl..ss.E-.sKchlcptcKDhEKpAuhLT+hlp..........
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