GenomeNet

Database: Pfam
Entry: DUF2321
LinkDB: DUF2321
Original site: DUF2321 
#=GF ID   DUF2321
#=GF AC   PF10083.12
#=GF DE   Uncharacterized protein conserved in bacteria (DUF2321)
#=GF AU   COGs;
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF AU   Sammut SJ;0000-0003-4472-904X
#=GF SE   COGs (COG4306)
#=GF GA   24.00 24.00;
#=GF TC   24.10 26.40;
#=GF NC   23.90 23.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR016891;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Members of this family of hypothetical bacterial proteins have
#=GF CC   no known function.
#=GF SQ   47
#=GS A0A6C2YL05_9BACT/5-158   AC A0A6C2YL05.1
#=GS Q3A032_PELCD/5-159       AC Q3A032.2
#=GS A0A5B9W6G0_9BACT/22-173  AC A0A5B9W6G0.1
#=GS A0A135L5H7_9BACI/4-139   AC A0A135L5H7.1
#=GS A0A1N6EYL4_9BRAD/86-162  AC A0A1N6EYL4.1
#=GS A0A242JYK3_9ENTE/2-157   AC A0A242JYK3.1
#=GS A0A0F5FMF3_9RHIZ/5-155   AC A0A0F5FMF3.1
#=GS Q97HR5_CLOAB/3-160       AC Q97HR5.1
#=GS A0A3N1UQR3_9DELT/5-159   AC A0A3N1UQR3.1
#=GS A0A1I4HIZ6_9FIRM/1-73    AC A0A1I4HIZ6.1
#=GS A0A0M0XD86_9BACI/3-157   AC A0A0M0XD86.1
#=GS M0BZZ7_9EURY/6-92        AC M0BZZ7.1
#=GS A0A1Q8QJK5_9FIRM/1-68    AC A0A1Q8QJK5.1
#=GS A0A3N1KRN6_9PROT/1-67    AC A0A3N1KRN6.1
#=GS A0A0R1RJ08_9LACO/3-155   AC A0A0R1RJ08.1
#=GS Q88LJ9_PSEPK/3-96        AC Q88LJ9.2
#=GS A0A2P8E3X9_9ACTN/21-154  AC A0A2P8E3X9.1
#=GS A0A1I0R250_9BACT/3-103   AC A0A1I0R250.1
#=GS Q8XW60_RALSO/3-158       AC Q8XW60.1
#=GS Q9PFM7_XYLFA/3-158       AC Q9PFM7.1
#=GS A0A6A7LF99_9ARCH/1-79    AC A0A6A7LF99.1
#=GS A3ZP13_9BACT/1-118       AC A3ZP13.1
#=GS L9VEB5_9EURY/1-101       AC L9VEB5.1
#=GS R6DLN7_9FIRM/3-153       AC R6DLN7.1
#=GS Q65PN4_LACJO/3-155       AC Q65PN4.1
#=GS A1ZK27_9BACT/8-97        AC A1ZK27.1
#=GS B2A6L3_NATTJ/23-177      AC B2A6L3.1
#=GS I4D747_DESAJ/20-98       AC I4D747.1
#=GS Q2RQ80_RHORT/14-169      AC Q2RQ80.1
#=GS A0A6B9YR26_9BACT/6-156   AC A0A6B9YR26.1
#=GS A0A660E224_9LACO/1-64    AC A0A660E224.1
#=GS G9ZRP6_9LACO/3-162       AC G9ZRP6.1
#=GS A0A5C5U7X0_9GAMM/3-158   AC A0A5C5U7X0.1
#=GS A0A658JIF6_9CLOT/3-152   AC A0A658JIF6.1
#=GS A0A0R1N080_9LACO/1-70    AC A0A0R1N080.1
#=GS A0A0G2ZGW2_9BACT/3-156   AC A0A0G2ZGW2.1
#=GS A0A1Q1PVY6_9CAUD/4-154   AC A0A1Q1PVY6.1
#=GS A0A2T4V0Y6_9DELT/7-149   AC A0A2T4V0Y6.1
#=GS A0A561QDP1_9BACL/3-161   AC A0A561QDP1.1
#=GS E8X823_GRATM/3-155       AC E8X823.1
#=GS U3PDZ3_9CAUD/3-153       AC U3PDZ3.1
#=GS C0GE89_9FIRM/3-158       AC C0GE89.1
#=GS V7FLP4_9RHIZ/12-166      AC V7FLP4.1
#=GS A0A5C6E4T6_9BACT/8-128   AC A0A5C6E4T6.1
#=GS Q6SEF3_9CAUD/3-155       AC Q6SEF3.1
#=GS A0A0R1HFY6_9LACO/44-198  AC A0A0R1HFY6.1
#=GS A0A5B2Z4C7_9ARCH/8-161   AC A0A5B2Z4C7.1
A0A6C2YL05_9BACT/5-158              .....................................YYDVAQVCPNGHVASSMAE.TCPQHRKPFCDKCGEATITSCPKCD.ARIRGY....YHVP.....GV-MLG....H..NYDPPGFCLSCGSPFPWTER..K.QQAAIDLfIEETQ--DQEARREFKESVEQIAKD..TPQAQVASLRITRLLEPIG.KFTAQAIRDILVDVASEMAKKF-l.....................................
Q3A032_PELCD/5-159                  .....................................YYDVAQICINGHVINSMAK.DYPQSNQKYCSDCGEETITACPSCG.SNIRGH....YHVP.....GVISFS....-..NFHAPSYCFNCGSPYPWTAI..R.LEAAAEL.ADELDGLTTDEKEKLKSSLPDLVKD..GPKTVVAETRFKKIIKKAG.ADAYEGMKTILVDVVSETVKKS-m.....................................
A0A5B9W6G0_9BACT/22-173             ....................................g-YDVAQVCMNGHMMNSASR.GMPDGNKSFCDRCGEKTITSCPSCN.NCISGL....DW-D.....GP---S....P..EPEPALHCEHCGKSYPWTER..K.KAAALEL.FAELLDLDNKQKEQLSQDLDAVASD..VPRTKVAAVRIDTLLAKVK.DQGADMLKGVLVEVMSESAKKM-m.....................................
A0A135L5H7_9BACI/4-139              ..................................sea---KVKVCLNGHIVK----.---ELEQNVCPKCGSQIITECPACH.SAFQEY....DH--.....------....-..---LPTVCVKCGHLYPWTKE..K.LQYLKEL.AEKMDYLTRDERNILEDSICEIIRE..TPFTPVAAIRVKKIIEKLG.PK-TSIFKDQLLDISSETAKEII......................................
A0A1N6EYL4_9BRAD/86-162             .......................hreaemrkliglle-------------------.-------------------------.------....----.....------....-..--------------------..-.-------.----EPLDHSEKAAVPAVVQNVMTE..TSFTPLAAERLKSMLSRLG.KSAYDVAIKIISDIGSATVKKM-l.....................................
A0A242JYK3_9ENTE/2-157              ...................................gq--QFQKVCINGHQISV-VS.TDPKAPEEFCQKCGKKVISTCQECH.YPIEGY....YKVE.....GIVDLR....A.rTAELPYYCKKCANPYPWTQL..I.MESATEL.LALDDEISDTDKELIKTAIPDLLVD..TPKTKLAEAKFKKGFSKAS.ALVKDSLYNLLVDVLSESVKKTI......................................
A0A0F5FMF3_9RHIZ/5-155              ..................................hfl---TGQACLNGHIVTGNIN.--DRDSTPFCAECGEATINACLSCT.KPLRGA....YETE.....YG----....Y.yPMKLPAFCYACGRPFPWTER..R.VQTAKDL.ADEVEGLDGAELTKAKDSFIVLVSD..TPQTPVAAARVTKLLQKAG.PVIGGGIRDIVVSIATDAAKRM-m.....................................
Q97HR5_CLOAB/3-160                  .....................................TYRTAQICLNGHEITTSAN.TSPELMENFCSKCGAATITNCPICN.TPIRGS....YHVE.....GVLSLG....H..EYKIPSYCHNCGKPYPWTKT..A.LESANAL.IEEDENLNSDEKKQFCETLPDLIVEspTPKTQLATARFKRLISKAA.TYTTDGVKGIIVNIASEAIKKS-l.....................................
A0A3N1UQR3_9DELT/5-159              .....................................YYDMAQICRNGHVITSMAQ.SSPQSKQKFFSKCGEETVTACDSRG.APIRGY....YHVP.....GVIAP-....L..DYQKPAYCYNCGSPYSWTVK..G.IEAASEL.ADELEGLTDDEKAQLKNSLPDLVNN..SARRTVAEIKFKKIMKKAG.SQAIAAMKEILFNVVNETVKKS-l.....................................
A0A1I4HIZ6_9FIRM/1-73               ....................................m-------------------.-------------------------.------....----.....------....-..--------------------..-.--AAKEY.VDFMEELSSEEKEALKNNIDDIITD..SPRTKLASQKVKYYLTKVG.KGLATGLKDILIDFASETAKKII......................................
A0A0M0XD86_9BACI/3-157              ....................................s-FDIAQICLNGHVINDTYV.KYPETNQKYCDKCGEKTIISCQNCH.TDIRGY....QYFE.....NVISMS....-..MVEPPSFCHECGKPYPWTEE..K.MAAAMEL.ADLLDELTEQEKDDLKKSLDELVKD..GPRTVVAATKFKRILSKTG.PEIATGFKDILVDVVSETVKKSI......................................
M0BZZ7_9EURY/6-92                   ................................dfdes-----------------TE.PDYEISSDYCPDCGGKVLTECRNCQ.SNIQIE....YNGP.....PY---P....N..LTHIPDFCDSCGESYPWVD-..-.-------.-------------------------..-------------------.-----------------------pvesekqregdfieiddtdidg................
A0A1Q8QJK5_9FIRM/1-68               ...................................mv-------------------.-------------------------.------....----.....------....-..--------------------..-.-------.--EYSKLNAADKKEFVDNIEIIASD..NPRTSLAAIKIKSIGKKLAgGLWNDVAKPLIVEIASETAKKS-m.....................................
A0A3N1KRN6_9PROT/1-67               ....................................m-------------------.-------------------------.------....----.....------....-..--------------------..-.-------.-DEMDELSDDEKRTLKQSVAEMTRD..TSATELASVRYKKLLGKAG.KGIGTALNSVTVSVITEAAKRL-l.....................................
A0A0R1RJ08_9LACO/3-155              ....................................t-KHKQLVCLNGHQIKDAME.-LSDSESGFCNKCGQPLISSCPKCG.HYIPGT....TDYE.....GVISFF....-..QEPVPKYCSNCGAPYPWTES..V.LKSATEL.IE-LTDLSQQDKDSFSKTIPDLVTD..TPKTKVAIAKFKIFSAKAG.KTVASGLKDLLVDVASEAVKKAI......................................
Q88LJ9_PSEPK/3-96                   ....................................q-QDAQQVCLNGHQITDSYH.RSREFRQRHCSQCGAETIHQCQSCG.IEIRGD....YHVE.....GFLALG....D..PTPIPANCEGCGTQFPWAQR..K.QEL----.-------------------------..-------------------.-----------------------aasagdpta.............................
A0A2P8E3X9_9ACTN/21-154             ....................................f-YLGAAVCKRGHVETVDLEpGGPVTVSDACPSCGARMLTACRSCG.VRIRGD....QFVP.....GVVSFS....-..TPRRPSFCDGCGAAMPWATRqeR.IHELENL.LDEAEEIDEADLVVIQDHLER----..-------------------.-----------------------lresslserdekaawsevkrrs................
A0A1I0R250_9BACT/3-103              ....................................k-QDTQEVCLNGHQITDRYY.SSPEFRKKFCTTCGEKTIHTCPSCA.KDIKGH....MIYE.....NVIDLS....G.rSTPVPNICDNCGADFPWREK..K.Q-KIKE-.-------------------------..-------------------.-----------------------lsnptnvekdatf.........................
Q8XW60_RALSO/3-158                  .....................................TYRVAQVCPNGHVATTAAD.QNPELREAFCSKCGEETIMQCPSCS.ASIRGD....FYVE.....GVFGLG....G..DYEPPSFCHNCGSRFPWTER..K.IAGAVEL.VEAGAELSPEEVQQFRTDLTELTKD..SPKTQVASLRFKKVMTKVG.ASVASGVRDIVVDVLSEAAKKAI......................................
Q9PFM7_XYLFA/3-158                  .....................................TYRAAQICTNGHVATTAAD.QKHELWEAFCSHSGEATILQYPKCS.ASIRGD....DYVE.....GVLGFG....G..DYEPPTFCNNCGSRFPWAER..K.IAGTVEL.VEAGTDLTPDEVQQFRTDLTQLTKD..SPKTQVTCLRFKKVMAKVR.TSVASGVRDIVVDVLSEAAKKAI......................................
A0A6A7LF99_9ARCH/1-79               .....................................-------------------.-----------------MTECQNCQ.YNVPGD....KYKP.....YFQSIG....-..-IHPPSYCDSCGSKFPRVKE..L.TKT----.-------------------------..-------------------.-----------------------lrkdelsrtdsaqswvesllsrfhsivktles......
A3ZP13_9BACT/1-118                  ....................................m-------------------.-------------------ACPDCQ.SPIQGH....YHCP.....GVIGFF....-..DYDAPHYCQNCGKAFPWTTR..A.LEAARQL.ATDDDTLSADESERFAKDLEEITRE..TPQAKASAGRIKKMLGKMT.AGTGAAIRDILIDIASESVRKMI......................................
L9VEB5_9EURY/1-101                  ..................................mtv----GAVCEDGHIRVIEAE.HEDIEHDPYCRKCGNQLHSVCPNCNnAPVKLD....GYTR.....DN---G....S.pHWRVQEYCHNCGEAYPWGPS..RfMEVTREV.AKRL---------------------..-------------------.-----------------------pepqdsrps.............................
R6DLN7_9FIRM/3-153                  ....................................p-YHIAQVCTSGHLITDCFD.VLEYERRNFCPKCGAPTITKCPACG.SEIYGA....--IE.....GS---R....C..DTTVDAYCSFCGTPYPWTSA..A.LQSAKAI.IEEAPELSDELKANTSGSLSDILVE..TPGTNLAIVRLKKVLQCAE.KFTCDALRQFVIDFGCELAKRS-l.....................................
Q65PN4_LACJO/3-155                  ....................................t-QYKQSICLNGHQITDEFS.-PNETVTGYCEQCGAKLIDSCPHCK.YPIEGF....YYPD.....GVVYLRs..pN.dKLPVPKYCKKCGTPYPWTKD..S.LDALNEV.IQ-LSNLSIQDKESLQASTPDLLVD..TPRTKVAVLKWKTI----G.KSILNLAHDIIVEVASESITKAI......................................
A1ZK27_9BACT/8-97                   ....................................n-QDVMQVCLNGHQITDSYL.RSPHLAEDYCQKCGKETIVACPNCQ.TPIKGD....YYYP.....GVVDLT....G.fRTPVPKRCSNCGKYYPWGKK..-.-------.-------------------------..-------------------.-----------------------lekvqrsk..............................
B2A6L3_NATTJ/23-177                 ....................................w-YDVAEICMNGHVTNSSVN.KNSQHCQDYCEKCGEKTIRECQDCS.TPIRGK....LHVE.....G--GFG....S.tHYYAPSYCHKCGNPFPWTEA..T.LKAAKEL.AQEVEEFSQEDIDIFTASLDDLIVD..NPHTKVAAVKFKKILSKAQ.QPMKDAIYQLLIDTVSETARKIV......................................
I4D747_DESAJ/20-98                  .................tyyminrssmkvtesetkdf-------------------.----------ETFNAKNISNCIKCN.AFIGGV....----.....------....-..---ESSYCHQCGTPYPWALN..K.YNDLIKM.VE-YFELNPEDA-------------..-------------------.-----------------------ec....................................
Q2RQ80_RHORT/14-169                 .....................................YYLTAQVCGNGHHTTSSVE.HSPNLMANFCDKCGSETMTKCPSCS.TKIRGK....YYVD.....DFAIIG....Q..NYTAPSFCHACGKAFPWTTT..K.IEAAKEM.VEEIDELSPDEREKLKGAIDDIVIE..GARTELGANRFKKLLTKMG.SASASAMRDIVVDVISETAKKII......................................
A0A6B9YR26_9BACT/6-156              ....................................e-YYGQVTCINGHVATNFYE.--GGDYQRWCGSCGKQTIAACPSCH.WPLRGS....-YRD.....L----I....H..SREPDAYCLHCGKALPWTES..K.LDAVREV.AKLVDGLTDNDRKTLNEILPDLISTeaTPSTQVAALKMKSLVKKGG.KVFAESVQKIIVDVISETAKKT-l.....................................
A0A660E224_9LACO/1-64               ....................................m-------------------.-------------------------.------....----.....------....-..--------------------..-.-------.----SDLNQNDKEDFKETIPNILTD..TPKTKVATTKFTVYAKKIS.SSLGSAIHDILVDVVSEAVKKAI......................................
G9ZRP6_9LACO/3-162                  ....................................i-QYAQSVCLNGHQASDNVS.-WGVQTTGFCDKCGAKLISICPSCK.NPIPGSidpnDYNS.....DVFILG....GptVTPVPKYCNSCGKPYPWTQS..A.IDSAKEL.IE-MSELDSTDKESFNESIPDLLVD..TPKTKLAITKFKIYTSKIG.SGIADGLKEVLVDVVSETVKRAI......................................
A0A5C5U7X0_9GAMM/3-158              .....................................TYRVAQVCPNGHVATTAAD.QNPELREAFCSKCGEATILQCPSCS.ASIRGD....YYVE.....GVFGFG....G..DYEPPSFCYNCGGRFPWTER..K.IAGAVEL.VEAGAELSPEEVQQFRTDLTELTKD..SPKTQVASLRFKKVMTKVG.TSVASGVRDIVVDVLSEAAKKAI......................................
A0A658JIF6_9CLOT/3-152              ....................................i-YNSATICLNGHVISSTRF.----DYTSYCDKCGNKSISICPSCN.TVIRGA....YENE.....--IAID....F..HYQAPSFCYSCGNPFPWIET..L.INNAVEL.IALDDNLSEENKAIIKSALPDLIVE..TPTTPLAAAKYKKFVPKAA.KYIQDGLRNLLVDVASEAVKKS-l.....................................
A0A0R1N080_9LACO/1-70               ...................................mq-------------------.-------------------------.------....----.....------....-..--------------------..-.------L.LNRSSKFSDQDQAEFAQIIPHLIIE..TEYTKSAKNKYQCLIRKAG.PATTNGLKEILAKVCSADVRKS-l.....................................
A0A0G2ZGW2_9BACT/3-156              .....................................TYHKALICKNGHIITDTID.TQPEKYEKYCSKCGAETIKKCEHCG.AFIRGD....YEIP.....GFVTIG....F..PPELPKYCHNCGKPYPWTEK..S.IEAAKEL.LMELDSG--YGEDFLNKTVEDLISD..DPETKVAIVRIKKMLAKAS.PEIGKLLKDILVGVVSEGVRKMI......................................
A0A1Q1PVY6_9CAUD/4-154              .....................................YYENATICLNGHVASSQVS.----NYIKFCKTCGESTISNCLKCE.FPIEGS....YRTR.....DFIDFT....-..TYNPPNYCHECGTAYPWTEK..I.LNNIIEL.VSLDDELSQEHRTIIKNAIPDLIID..SPTTPLAQAKYKKYMSQAA.EYVQEGARNLLIDLVSEAVKKS-l.....................................
A0A2T4V0Y6_9DELT/7-149              .................................pgda-------------------.-------AFCRDCGARAVKTCGQCS.AHIQGV....RIPPlhtrrDFSMLPspeaQ..PYRIPAHCPQCGHAYPWTEA..R.LKAAAEL.VDLAEALSAEERAQLKADLPALANE..GPQSPVTAQRWKKGLAKVG.GDLYGVRMKVLGDLVTASVK---gql...................................
A0A561QDP1_9BACL/3-161              ....................................q-FDVAQICLNGHIINYHAK.NESFLNKDFCTSCGEKTITQCQCCT.HEIRGE....YSGS.....SWYGYDa.ysG..LFNCPSYCEKCGKAFPWTLS..R.IEAAQEL.ARELEGLTEEEREILANSINDIVKD..SPRTIVATTRFKKVVSKVG.LPVANAFKEILTDVVSETVKKS-l.....................................
E8X823_GRATM/3-155                  faaycknghlvgivqsprtgsdlrrlaerhatgipff-------------------.------SPFCKECGEATVSQCPHCE.ARIELN....----.....------....-..----AKYCGSCGKVLPWTEN..A.LAAARAY.TDDLDEFTSDEKEKLNENFKVLTKD..SPSVPLAVRLLQKAVAKAG.PVVGSAILEIAKTLATAEAKK--hl....................................
U3PDZ3_9CAUD/3-153                  .....................................YYENATICLNGHVSSS-IN.---AKYRKFCKECGESTISNCLNCG.SAIQGS....YCIP.....NFIGPS....-..DFQFPNYCHECGNPYPWTEK..L.LNNAVEL.VSLDEELNENQKEIIKNAIPDLIIE..SSSTPVAQAKYKKYMSLAA.EYVQEGTRNLLIDVVSETVKKS-l.....................................
C0GE89_9FIRM/3-158                  ....................................r-YDEALICKNGHVINESAN.RNPEFNTKFCDKCGAETIRKCLNCG.TGIRGE....YHVE.....GVFDLT....G..HSPAPSYCHDCGKPYPWIEE..Q.LNALDEI.VDLMDELSELEKQEFKQSAREVTTE..NPRTSLAALKIKKFGIKVG.SEVYGAARDILVQIAVEAALKS-s.....................................
V7FLP4_9RHIZ/12-166                 ....................................i-YKVGQVCVNGHAITGNVE.--AAASSKFCPRCGEETIVTCPSCR.ASIRGN....RIIR....sDFGNIS....S..GMHIPAFCHACGKPFPWTER..A.VAAAKEL.VDEVEGIETDEREKAKSSFIALASD..TAQTTVAATRVNKLIAKAG.PILGKGIRDIVVSIATDAAKKA-m.....................................
A0A5C6E4T6_9BACT/8-128              ....................................w-YDTMQVCYNGHQITNFVE.SQPESTRKRCDECGEPTTDHCLKCK.AKIIGY....HHIP.....GVIGFS....-..GPDPPAHCHECGEAHPWTER..R.KE-----.-------------------------..-------------------.-----------------------igdnttkvkseqtnkifivhghddamkeavarvvsklg
Q6SEF3_9CAUD/3-155                  ....................................t-QYKQSICLNGHQITDEFS.-PNETVTGYCEQCGAKLIDSCPHCK.YPIEGF....YYPD.....GVVYLRs..pN.dKLPVPKYCKKCGTPYPWTKD..S.LDALNEV.IQ-LSNLSIQDKESLQASTPDLLVD..TPRTKVAVLKWKTI----G.KSILNLAHDIIVEVASESITKAI......................................
A0A0R1HFY6_9LACO/44-198             ....................................t-QYSQSVCLKGHQISSFIT.TSSENPKEFCEDCGSEVITHCPSCN.KSINGY....LQLD.....GV--FG....G.yDVPVPSYCRNCSSPYPWTST..A.LESLKEL.INLQDELNDEEKDDFSSSLPDLISN..GPKSKVAITKFNKYSSKIS.SGFRNFAVEIISSIASDVIVKS-l.....................................
A0A5B2Z4C7_9ARCH/8-161              .....................................TYYHAIICLNGHIISDSIE.-SFETKMGFCKDCGKPTINKCQNCK.NPIHGD....MYIP.....NFVNAI....-..QMESPSFCYGCGNPYPWTKS..K.INALEEL.IDFEEKLSETNKEDLKKNINDIINE..TPRTKIATIKFKHLLTKMG.KETGIMAKNLAVEMASETAKK--yf....................................
#=GC seq_cons                       ........................................httlChNGH.hss.hp....t..ptaCpcCGtpsIspC.pCp.ssIpGt....hhh......sh..ht.......th..PsaCppCGpsaPWTpp..t.lpshhEl.hp.hppLstp-+pthppslsclh.-..sPpT.lAth+hKphhtKhu.t.htssh+plllclsSEssKK........................................
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