#=GF ID   DUF3573
#=GF AC   PF12097.11
#=GF DE   Protein of unknown function (DUF3573)
#=GF AU   Assefa S;0000-0003-2178-533X
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   PFAM-B_2286 (release 23.0)
#=GF GA   26.60 26.60;
#=GF TC   26.90 28.80;
#=GF NC   26.30 26.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0193
#=GF DR   INTERPRO; IPR021956;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   protein is found in bacteria. Proteins in this family are
#=GF CC   typically between 372 to 530 amino acids in length.
#=GF SQ   8
#=GS A0A1E3GDA8_9GAMM/83-291   AC A0A1E3GDA8.1
#=GS Q5NI23_FRATT/16-237       AC Q5NI23.1
#=GS A0A371RF89_9PROT/62-240   AC A0A371RF89.1
#=GS Q5NGC6_FRATT/100-341      AC Q5NGC6.1
#=GS Q5NH68_FRATT/10-373       AC Q5NH68.1
#=GS Q5NIP1_FRATT/1-374        AC Q5NIP1.1
#=GS Q5NGC7_FRATT/4-422        AC Q5NGC7.1
#=GS A0A0K2DUN8_PISSA/101-299  AC A0A0K2DUN8.1
A0A1E3GDA8_9GAMM/83-291              lkllkkagedaprftlggileadisygkdttaadsgvagdgiynt------------------------..........................--------------------------------------------.......----------------------------------...------------------------------------------------------------------------------------------------------------....----NGYAEGQtasSI..YLDTVRLDILAKLNDWVLVDWQLDIAKS......SPLRT--GFVTFGNLSKSPVYFSLGKIV.PYFGDFGGHTYNNPLST..DYFriSKGKLA-GTLGYYQDNLNISASVFE....T....DRGTAA----DNHVNDWTLQANYAFKVGQVKAKVGAG---------------------yvrditghalrgmtakdt.......
Q5NI23_FRATT/16-237                  ..........................................mkn------------------------..........................--------------------------------------------.......----------------------------------...----------------------------------------------------------------RISKNLYASTIIGQRDKFPNYSMFFGGYFEGDAQTWFGSQINRA....GGTSDFPATGQ...NI..YMTTVDLYFLANVGEYMTAVFDFLTDDN......SDFGLRNGFVILGNLDTSPFFVTVGKNRrISVGTYGGGGPWSNGLS.eDFL..APGSVTNISLNYKTSSINANVTTFG....T....QNNHLDFSAAIFYANKLTTDLSYGLNFGYIFNLAGADNTSISKFLDSIDKGNDSVGT-i........................
A0A371RF89_9PROT/62-240              .....................................eagelktn------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------------------------------------------------------------SIYVGGLIRGGLYKEQTNTAGKFpilsRFPFQHDSDTD...NTeaLIQNAAVTFTGNFGKWITGFAQIEHSEVfyrpdqDNVQLREAYVIFGNLEQSPFYAAVGRKT.VDFGQFDTFTPFTHSVNqhYFW..TLSDDPVVEVGYIGDTFRVS-----....-....----------------------------------------------------------gtlingsrqmrvaysdnddvfgnfa
Q5NGC6_FRATT/100-341                 .........................................sssd------------------------..........................--------------------------------------------.......----------------------------------...-------------------------------DREVDVGNQVKITTQGEISYVGSFSSNNTVPIGQLPSNLFASSILRQRAFFDDYSIFFGGFIQADAQIWNGTDITT-....RNGGNFTGNGE...NI..YLTSATLYFLANLGHYVTANLDFVANQN......NNYDLQDAFVIFGNLDTTPVFVSVGKYR.PSVGSFGGGGPWTSGIT.aNMF..RPLRVTNAAINYRGDTSNANFTVFD....A....K-NHATFSVAYFDAVSIPNIAQVGFNLGYMHDIRGANNR-------------------fnfidkrv.................
Q5NH68_FRATT/10-373                  .............................................YIYKKLLIY-SFFMCSIC------..........................HSYAELNNQIS---------ILELQKQIKELQTEINHFEETKI-.......NENFEFTTYSSEVVDSK---SKLRNKETKVLYTV...QNNNVDIIQNISPESTIIDLRGKPLGKIFNQNGSIDVGNAPAITTDGQAAYLGSYSGNNSIPIGMIPGKLFASTIILQKEKFDQYSIFLGGLIRVDAQTWFGDSIPRVdfnnNPTTSFDSKGQ...NI..YPSTARLFFLANMGNYITAAYNVSTSEL......NNFNIGDAFVIIGNMDVSPYFITVGKST.LTIANLGGGGPSTSGIA..NFL..NTGRATNISLNYKTSTLNVSVAFFS....T....NDQKANFSAGLFYADKWTDNLSVGFNTGYVYDLAGAENSSIPRIALN-----KTIGAFsi.......................
Q5NIP1_FRATT/1-374                   .............................................MLNKINIVFICFLVLSITPFMGFS..........................NSFKNSNEQSQKSNSIDKQGITQLQSQIANIQAEINHLTQIKNS.......NNSAQFATYSSKVENIGLPNSLPDN---------...NKLTLDIMTNIDSDSSIINLSDCSIGGIFDKDGGINVGGAPAITTQGEVTFLGAYSGNNTVPIGMISSNLFASTVMGLRNKFDSYSIFFGGKIEADAQLWFGSSTIS-....NKATNLASNGQ...NI..SLTAANLYFLSNVGHYVTAEIEFNTTEL......NNFSLGNAFVIFGNLDTSPFFLTAGRNK.LSVGAFGGGGPWTGGIT.kNFL..SPGKVTNVSLNYKSDVWNANVAVFG....S....NDNQFNFSTGLFYAQKWTQDIAVGFNTGYVYNMAGAGNPSLSRFLQSQGHPTDTIGSF.........................
Q5NGC7_FRATT/4-422                   ...........................................kf--KKTCLIVSSLLACSGLAYSEDSpqvvsqggplgatsigdqnlgqpdpnASGASSTTQTTGSNLNDRELLLKLQQQVQQLQGQLQQLKAQGNGgglqntyNGSSQFTTYSSKVDGNKNPRTLGGNGESKDLSQAligGQTSSDIMGNVNASNSIINLASEPLGGVFNQKGGIDVGGAPAITTQGQVTYLGSYSGNNSIPIGQISSNLFASTLLGQREKFDDYSVFFGGFIEADAQAWFGSAVTKV....QNAGQLSSNGQ...NI..YLTSANLYFLSNLGHYVTAQFDFDTNES......GSFSLGNAFVIFGNLDISPFFVTAGRNK.LSVGSYGGGGTWTSGIT..KFL..SPNQVTNVSIDYKDQVWNANIAVFG....S....DDRRANFSTGLFYADSWTPNLAAGFNVGYVFNIAGAGNSSIANSLANLNRSSDNVGAL.........................
A0A0K2DUN8_PISSA/101-299             ...........llsigglletdigygrntnldadyfhksqslshs------------------------..........................--------------------------------------------.......----------------------------------...------------------------------------------------------------------------------------------------------------....-----------...DA..EVTAARLHIMANINDWTTGFFYYDML-A......NNLRTGK--ITFGNLNETPFYASIGKSY.SYFGNWSGPNIITTDVD..ASL..FESRSNNAMLGYTQGGFNAQVGLTSpastVntpnHNNHAGFLTQAHYTLDLGNNNSAYLGAGYMSDLHGTEVSALSQAQAADGH--------tripaa...................
#=GC seq_cons                        ...........................................ps...........................................................................................................................................................................................................lstpLaASolhh.+thFspYSlFhGGhIcuDAQhW.Gsshsp.....p.ssshsusGQ...NI..YlToAsLaFLANlGcYlTAtapasss-s......sNasLtsAFVIFGNLDpSPFFlolGKsp.lolGsaGGGGPaTsGlo..sFL..ssu+lTNloLsY+ssshNAslulFu....o....pss+AsFSsuhFYAschTsshusGFNsGYlaslsGAsNsulsp...s...........h........................
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