GenomeNet

Database: Pfam
Entry: DUF4318
LinkDB: DUF4318
Original site: DUF4318 
#=GF ID   DUF4318
#=GF AC   PF14201.9
#=GF DE   Domain of unknown function (DUF4318)
#=GF AU   Eberhardt R;0000-0001-6152-1369
#=GF SE   Jackhmmer:B0PDG9
#=GF GA   27.00 27.00;
#=GF TC   29.50 29.90;
#=GF NC   26.30 25.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 61295632 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR025467;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family of proteins is functionally uncharacterised. This
#=GF CC   family of proteins is found in bacteria. Proteins in this family
#=GF CC   are approximately 80 amino acids in length. There is a single
#=GF CC   completely conserved residue F that may be functionally
#=GF CC   important.
#=GF SQ   55
#=GS R5WPL6_9FIRM/3-73         AC R5WPL6.1
#=GS U2EGJ0_9FIRM/139-212      AC U2EGJ0.1
#=GS R5RHZ8_9FIRM/148-220      AC R5RHZ8.1
#=GS A0A6L7HKM9_BACAN/14-84    AC A0A6L7HKM9.1
#=GS A0A417HK33_9FIRM/3-73     AC A0A417HK33.1
#=GS A0A173X260_9CLOT/149-221  AC A0A173X260.1
#=GS B6FXK9_CLOHT/5-75         AC B6FXK9.1
#=GS A0A386PFR4_CLOSE/2-74     AC A0A386PFR4.1
#=GS A0A367GFG7_9FIRM/3-73     AC A0A367GFG7.1
#=GS A0A1B8ULG7_9BACL/11-80    AC A0A1B8ULG7.1
#=GS R8W0X2_9CLOT/5-74         AC R8W0X2.1
#=GS R6Z521_9CLOT/6-76         AC R6Z521.1
#=GS B0PHJ1_9FIRM/3-73         AC B0PHJ1.1
#=GS A0A416JM35_9FIRM/3-73     AC A0A416JM35.1
#=GS A0A396PU27_9CLOT/3-73     AC A0A396PU27.1
#=GS A0A2Z4UEK7_9FIRM/146-217  AC A0A2Z4UEK7.1
#=GS A0A1L8ZRI1_9BACI/14-84    AC A0A1L8ZRI1.1
#=GS U2AZI2_9CLOT/136-207      AC U2AZI2.1
#=GS K8ESY8_CARML/6-77         AC K8ESY8.2
#=GS R8W248_9CLOT/148-218      AC R8W248.1
#=GS A0A4R4ELH5_9BACL/13-83    AC A0A4R4ELH5.1
#=GS F7K8A0_9FIRM/136-207      AC F7K8A0.1
#=GS Q81E39_BACCR/14-84        AC Q81E39.1
#=GS R6N801_9FIRM/145-217      AC R6N801.1
#=GS A0A2U1AU98_9FIRM/3-73     AC A0A2U1AU98.1
#=GS A0A373BJA7_9FIRM/3-73     AC A0A373BJA7.1
#=GS F3BCP9_9FIRM/137-210      AC F3BCP9.1
#=GS A0A412LAI8_9FIRM/144-216  AC A0A412LAI8.1
#=GS H3SLC5_9BACL/11-80        AC H3SLC5.1
#=GS A0A1T2X4R3_9BACL/11-80    AC A0A1T2X4R3.1
#=GS A0A2K2TZE0_9CLOT/3-73     AC A0A2K2TZE0.1
#=GS A0A395YKX3_9CLOT/20-88    AC A0A395YKX3.1
#=GS A0A2Y9C5A2_9FIRM/141-213  AC A0A2Y9C5A2.1
#=GS B0PDG9_9FIRM/3-73         AC B0PDG9.1
#=GS D9R3D8_CLOSW/139-211      AC D9R3D8.1
#=GS A0A1I0V544_9CLOT/6-76     AC A0A1I0V544.1
#=GS A0A4S2DM28_9CLOT/9-82     AC A0A4S2DM28.1
#=GS A0A544QT05_9FIRM/3-71     AC A0A544QT05.1
#=GS U2DBG3_9FIRM/14-83        AC U2DBG3.1
#=GS A0A2Y9BEF2_9FIRM/6-76     AC A0A2Y9BEF2.1
#=GS A0A1M6R8F1_9CLOT/10-80    AC A0A1M6R8F1.1
#=GS A0A429ZP06_9ENTE/17-92    AC A0A429ZP06.1
#=GS A0A1Y4UIC4_9FIRM/3-73     AC A0A1Y4UIC4.1
#=GS A0A1M6LTK8_9CLOT/139-212  AC A0A1M6LTK8.1
#=GS L1QBY7_9CLOT/131-204      AC L1QBY7.1
#=GS F7KCT2_9FIRM/6-75         AC F7KCT2.1
#=GS A0A395YKC2_9CLOT/3-73     AC A0A395YKC2.1
#=GS A0A1Y4NCF6_9FIRM/3-73     AC A0A1Y4NCF6.1
#=GS A0A1Y4LAG2_9FIRM/3-73     AC A0A1Y4LAG2.1
#=GS A0A1Y4SWW4_9FIRM/6-76     AC A0A1Y4SWW4.1
#=GS A0A2A7MEX1_9CLOT/3-73     AC A0A2A7MEX1.1
#=GS F0Z029_9CLOT/141-213      AC F0Z029.1
#=GS B6G281_CLOHT/149-220      AC B6G281.1
#=GS U2B0Z0_9CLOT/21-90        AC U2B0Z0.1
#=GS A0A0J1FY60_9FIRM/136-209  AC A0A0J1FY60.1
R5WPL6_9FIRM/3-73                    ..............KKAFWIPYED.SAeYPTMVKAM-QAISEYCEKNGDSCTFTGD..D---EVEINGKVY--EICRGYEN.GSRGnYGIKCKEK.............
U2EGJ0_9FIRM/139-212                 ....rvtliedlla----------.--.RPQTEDMFMKEIEVYCNKNHLTLEVIKS..GIPAKVKMDNTPYLVKLGQYYSM.IGTIvYTLEFS--si...........
R5RHZ8_9FIRM/148-220                 .............t-KTLLVDLEG.R-.-PKNVDEFCSYIEAYCSENQITLEFLHR..GVPALILMDGKECTVELESYYSQ.FGPV.YGMKFIE-t............
A0A6L7HKM9_BACAN/14-84               .............s-KSFFIELDD.ALtYPSGE-VITSAIESYTAECNEQLKFESK..VKPIIFYLEEVLYRAEVKM--AR.GG--.YYISCSEV.............
A0A417HK33_9FIRM/3-73                ..............KKAFWVPYED.STnYPTLAKTM-EAISKYCEENGESYTFIND..D---EVEINGKRY--EIYRGYEN.GSRGnYGIKCKEK.............
A0A173X260_9CLOT/149-221             .............g-RTLIIDLDE.K-.-PRSPEAFFDLLETYCRKSSVTLEYVKK..DIPATVKLEGRLHTVTLTESYMY.GGPV.WSMEIREI.............
B6FXK9_CLOHT/5-75                    ..............KKSIILDIED.PT.KPRNLVETIKAVEKYCEENHQTCKFISD..N---EVEIDGVLY--EVAEPEGT.IMRGnYFVKIKE-k............
A0A386PFR4_CLOSE/2-74                ..............KKCFVINLNE.K-.-PNNSQEICEYISKYCNKQNQYFEFTSR..KTPISFYLENTLYRVKLGKSFKN.FYYR.WILYCNE-v............
A0A367GFG7_9FIRM/3-73                ..............KKSIWIPYED.STvYPTVAKAQ-QAIIKYCEDNGFLYEFTAD..D---EVVIDGIKH--EIYRGYDS.GSRGnYGIKCREK.............
A0A1B8ULG7_9BACL/11-80               ..............KKGFSVELDQ.L-.-PQNKQQFLDEIERYCVQEKVNYKFIEY..DRPAVISIDGVVYKCHVENA---.GRPG.FVLHFKE-v............
R8W0X2_9CLOT/5-74                    ............hp--SFWVTYDK.ST.YPTVADAQ-QAIERYCRENGHTCRFLED..D---TVEIDGVPH--EIYRGYEP.GSRGnYGIKCRK-l............
R6Z521_9CLOT/6-76                    ..............KKSFWIPYED.STvYPTMAKAM-EEISRYCEERGETCVFTGD..D---EVEIEGKRY--EIYRGYEN.GSRGnYGIKCREK.............
B0PHJ1_9FIRM/3-73                    .............r-KSFQIELED.SLtYPS-ARIICEAVESYAAGSKERLTFVSR..EMPVSFYLDQDLY--EVKIIMIR.GG--.YELSCRK-r............
A0A416JM35_9FIRM/3-73                ..............KKAFWVPYED.SAnYPTLAKTM-EAISKYCEENGKSYTFIND..D---EVEINGKRY--EIYRGYEN.GSRGnYGIKCKEK.............
A0A396PU27_9CLOT/3-73                ..............KKAFWVPYED.SAnYPTLAKTM-EAISKYCEENGKSYTFIND..D---EVEINGKRY--EIYRGYEN.GSRGnYGIKCKEK.............
A0A2Z4UEK7_9FIRM/146-217             .............r-QVFLADLEE.C-.-PQSVEAFCIEIERYCLKNHRSLEFVKR..DKPAEICMDGEHYFVELDSYYSQ.FGPM.YSLKFI--h............
A0A1L8ZRI1_9BACI/14-84               .............s-KSFFIELDE.ALtYPSSKVIT-SAIEGYATECNERLKFESK..VKPITFYLENAMYRAEIKM--AR.GG--.YYISCTEV.............
U2AZI2_9CLOT/136-207                 .............y--TLRIDLKE.K-.-PSSKEDFLRQFEAYCVKENIDLVYEVK..DVPAVVLMNGVRCEVSLDSTPGF.GGAD.YVMKVTE-r............
K8ESY8_CARML/6-77                    ..............KRGFLVEATG.EV.YPSSDQSVCQSIEEFISPSQK-LEFLSQ..KKPVTFYLDGILYQAEVNEAQSR.GG--.YFINCTEV.............
R8W248_9CLOT/148-218                 .............a--SLIVDLDD.C-.-PKGIEAFCIEIERYCIKNHIDYQFIER..DKPAIVLMNGVKHRVELGVYYG-.YVPG.WFLKFTE-l............
A0A4R4ELH5_9BACL/13-83               ..............KKGFHIEIDD.ALtYPS-KQTICQAIEQYAAENKKQVQFVSS..VQPLTFLYESRQYYVDI--RMSR.GG--.YTIFCREV.............
F7K8A0_9FIRM/136-207                 ............ya---LCISLKE.K-.-PSSKEDFLRKFEDYCYRENISLEYEVK..DVPAIVLMDGIRCEVRLDSTPGF.GGAE.YMMKVTE-e............
Q81E39_BACCR/14-84                   .............s-KSFFIELDE.ALtYPSSKVIT-SAIEGYATECNERLKFESK..VKPITFYLENAMYRAEIKM--AR.GG--.YYISCTEV.............
R6N801_9FIRM/145-217                 ..............KRVMLVDLDE.C-.-PKSVEAFCIEIERYCIKNGRSLKFVKR..EKPAEIYMDNEHYMVELDSFYQR.FGPM.YALKFIQI.............
A0A2U1AU98_9FIRM/3-73                ..............KKAFWVPYED.SAnYPTLAKTM-EAISKYCEENGESYTFIND..D---EVEINGKRY--EIYRGYEN.GSRGnYGIKCKEK.............
A0A373BJA7_9FIRM/3-73                ..............KKAFWVPYED.SAnYPTLAKTM-EAISKYCEENGKSYTFIND..D---EVEINGKRY--EIYRGYEN.GSRGnYGIKCKEK.............
F3BCP9_9FIRM/137-210                 .......kdfvlie------DLKR.--.KPRNEEEFIKFIILYCEKNALELEILQY..GEPAKVKMGGRVYTVKIVEYCSL.SNGVaYAMEFR--c............
A0A412LAI8_9FIRM/144-216             .............t-KTLLVDLEE.K-.-PESVEEFCNQIRSYCEKNHQTVEFLTK..GRTCEILLDGKPCTVELDSYYSQ.FGPM.YSMKFI--wk...........
H3SLC5_9BACL/11-80                   ..............KKGFSVELDQ.L-.-PKNKQAFLDEIERYCIKEKVTYEFIER..DRPAIISIDNVVYQCQVENA---.GRPG.FVLHF---kem..........
A0A1T2X4R3_9BACL/11-80               ..............KKGFSIELDQ.L-.-PKSKEEFLQAIECYCIKEEVPYEFIER..DRPAIISIDRVVYKCQVEN---K.GLPG.FVLHFKE-i............
A0A2K2TZE0_9CLOT/3-73                ..............KKAFWVPYET.SDvYPTVKKAQ-QAISKYCEENGYSYSFPGD..D---EVVIDEKTY--EIYRGYQL.GSRGnYGIKCREK.............
A0A395YKX3_9CLOT/20-88               ...........erv----LIETLN.R-.KPENADEFYNEIEEYCRKNHKELEFVEK..AVPALVRIDGRIHRVELRFFYVT.----.YVLKFTQ-l............
A0A2Y9C5A2_9FIRM/141-213             .............g-RYLVVDLEE.C-.-PRSVDAFCREIEDYCRKNRITLEFITR..GKPAVVKMDGQTYHVELDSFYSQ.FGPM.YALKFGQ-y............
B0PDG9_9FIRM/3-73                    ..............KKAFWVPYED.STnYPTLAKTM-EAISKYCEENGESYTFIND..D---EVEINGKRY--EIYRGYEN.GSRGnYGIKCKEK.............
D9R3D8_CLOSW/139-211                 .............g-RTLVIDLKD.K-.-PGTKEEFFSVLEDYCIKNRLSLEYVKR..EIPAVVKLDGVLHEVDLRSYYTY.GGAI.YTMDIT--kl...........
A0A1I0V544_9CLOT/6-76                ..............KKSFLVDLDD.SLtYPS-AQIICNAIEKYCVGSKEKCHFVST..EKPVTFYLKDKLFSAKI--IMAR.GG--.YIINCRE-d............
A0A4S2DM28_9CLOT/9-82                ...........kis---IDIPYEN.YTvYPTVSITK-DAIINYCIKENIDFEFLENnsDNNMQVKLDNKLY--EILRFNAG.RG-G.YGIKCR--pv...........
A0A544QT05_9FIRM/3-71                ..............RKSFWIPYENgDV.YPTVSIAH-IEIEKYCIKNGHKYSFVSD..D---EVEIDGKVY--EIYRGCEV.RG-N.YGIKCTEK.............
U2DBG3_9FIRM/14-83                   .............s-KSWVIDLKD.CTsLPSSNTII-ETIQEWASNSHKKITFIST..EKPVTFMLDGTKYIANINKE---.----.--------rwaytlyitd...
A0A2Y9BEF2_9FIRM/6-76                ..............KNSFGVPYEN.GGiYPTVAKAQ-QAISKYCEENGYSYSFNGD..D---EVIINEKTY--EIYRGYEN.GSRGsYGIKCRE-r............
A0A1M6R8F1_9CLOT/10-80               ..............KKAFYIDLED.SLnYPSP-KKICEAVTKYCIANKETFEIIKS..STPVTFRLDNTLY--EATVGMAR.GG--.YILHCKEI.............
A0A429ZP06_9ENTE/17-92               lfiepyqqeetllt----------.--.----DSLICTSIEHYAQKNNLELSFTSQ..ESPITFELADVAYVANVDSLLNQ.IG--.--------gttplasiacrqi
A0A1Y4UIC4_9FIRM/3-73                ..............KKSFIIELDD.SLkYP-NAETICNLVEKYAVKNNEILKWESK..EEIIKFYLSNVLY--EVKIHMIR.GG--.YEILCKEV.............
A0A1M6LTK8_9CLOT/139-212             .........srtli-----EDLPR.K-.-PQTEDIFMQEIENYCTKNYLSFEIINY..GIPAEVKIDNTLYTVKLGQYYSVlGSPI.YTLEFHN-i............
L1QBY7_9CLOT/131-204                 .............h-KTLIVDLKS.K-.-PKTKEEFFRVLEENCMSNGDSLEYIER..DIPAVIRINGILYKAEIGYYYSV.AGEAvYTLRITE-f............
F7KCT2_9FIRM/6-75                    ..............KKAFDVPYED.ISeYPTPAKAM-EAISKYCEANGETCVFTGD..D---EVEISGIKY--EICRGVSP.LNLG.YGIACKEK.............
A0A395YKC2_9CLOT/3-73                ..............KKSFWVPYEE.SGtYPTVTKAM-AAISKYCDDNGDSYMFTGD..D---EVEINGKKY--EIYRGYEN.GSRGnYGIKCKEK.............
A0A1Y4NCF6_9FIRM/3-73                ..............RKSFWVPYED.GTsYPTVSKAK-EAISKYCEESGETCVFISD..E---EVKIGEKLY--EIYRGYES.GSRGnYGIKCTEK.............
A0A1Y4LAG2_9FIRM/3-73                ..............KKAFWVPYDE.SDiFPTIVNAH-QAISKYCEENGYSYSFSSD..D---EVVINDKLY--EIYRGYEN.GSRGnYGIKCTEK.............
A0A1Y4SWW4_9FIRM/6-76                ..............KKAFWVPYEP.ADvYPTVQKAH-QAIAAYCEKNGLSCTFPSD..D---EVLIDEKLY--EIYRGYES.GSRGnYGVKCREK.............
A0A2A7MEX1_9CLOT/3-73                ..............KKAFWVPYED.SGsYPTLTKAI-EAISKYCDENGDSCIFTGD..D---EVEINGKKY--EIYRGYEN.CSRGnYGIKCREK.............
F0Z029_9CLOT/141-213                 .............g-RYLVVDLEE.C-.-PKGAEAFCREIEDYCRKNRSSLEFLKR..EKPAEILMDGERYHVELDFFYSQ.FGPM.YALKFRK-e............
B6G281_CLOHT/149-220                 .............n-KTLYIEVDR.R-.-IETIEEFFEEINKYCSQFEN-VEYVSM..DLPALIRIDGVLYEADIVEYYSV.VG--.--------tpitaisikt...
U2B0Z0_9CLOT/21-90                   ............hv--TFDVPYEE.ISeYPTPAKAM-EAISRYCEASGESCVFTGD..D---EVEIAGRKY--EVCRGANP.LNLG.YGIICREK.............
A0A0J1FY60_9FIRM/136-209             ............rs--ALVVDLDE.K-.-PATMEAYFHEIEKYCEANHWNLEYIKK..EKPALIRINGKKYAVKMGLYYTP.IGTIvYTMTFS--sa...........
#=GC seq_cons                        ...............KuFhlsh--.s..hPssscsh.psIpcYCpcNspohpFlsc..-.shplpl-GphY..Eltphapp.Gu.h.Ysl+spE..............
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